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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Bhlhe40

Z-value: 1.50

Motif logo

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Transcription factors associated with Bhlhe40

Gene Symbol Gene ID Gene Info
Bhlhe40
ENSMUSG00000030103.5 basic helix-loop-helix family, member e40

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_108709314_108709465Bhlhe40463430.1162910.739.9e-02Click!
chr6_108668460_108668647Bhlhe4055070.177493-0.711.2e-01Click!
chr6_108704850_108705008Bhlhe40418830.123574-0.691.3e-01Click!
chr6_108670913_108671087Bhlhe4079540.168584-0.651.6e-01Click!
chr6_108664929_108665106Bhlhe4019710.2781220.651.6e-01Click!

Activity of the Bhlhe40 motif across conditions

Conditions sorted by the z-value of the Bhlhe40 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_93323421_93323587 1.31 Ccng2
 cyclin G2
 54796
 0.1
chr5_25015695_25015994 1.25 Prkag2
 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
 20091
 0.17
chr19_4201629_4201786 1.07 Rad9a
 RAD9 checkpoint clamp component A
 45
 0.5
chr19_7240751_7240928 1.03 Naa40
 N(alpha)-acetyltransferase 40, NatD catalytic subunit
 195
 0.89
chr7_81002031_81002182 0.97 Gm44967
 predicted gene 44967
 7423
 0.11
chr19_23074772_23074923 0.95 C330002G04Rik
 RIKEN cDNA C330002G04 gene
 1006
 0.54
chr3_121735675_121736039 0.95 F3
 coagulation factor III
 6310
 0.11
chr4_149426608_149426780 0.91 Ube4b
 ubiquitination factor E4B
 55
 0.96
chr2_103592357_103592552 0.90 Abtb2
 ankyrin repeat and BTB (POZ) domain containing 2
 26144
 0.17
chr13_38849595_38849761 0.86 Gm46392
 predicted gene, 46392
 12052
 0.18
chr6_115838132_115838303 0.85 Efcab12
 EF-hand calcium binding domain 12
 195
 0.88
chr5_136170628_136170833 0.82 Orai2
 ORAI calcium release-activated calcium modulator 2
 17
 0.96
chr17_24205766_24206106 0.81 Tbc1d24
 TBC1 domain family, member 24
 374
 0.68
chr9_44079482_44079643 0.81 Usp2
 ubiquitin specific peptidase 2
 5377
 0.08
chr5_115010965_115011126 0.80 Sppl3
 signal peptide peptidase 3
 92
 0.94
chr17_12769661_12769836 0.78 Igf2r
 insulin-like growth factor 2 receptor
 84
 0.95
chr10_43742623_43743061 0.76 Gm40634
 predicted gene, 40634
 245
 0.89
chr9_49365685_49366095 0.75 Drd2
 dopamine receptor D2
 25263
 0.2
chr1_143739744_143740319 0.73 Glrx2
 glutaredoxin 2 (thioltransferase)
 344
 0.84
chr11_117780625_117780787 0.72 Tmc6
 transmembrane channel-like gene family 6
 48
 0.93
chr19_30096271_30096642 0.71 Uhrf2
 ubiquitin-like, containing PHD and RING finger domains 2
 4495
 0.24
chr15_58972603_58972890 0.70 Mtss1
 MTSS I-BAR domain containing 1
 207
 0.92
chr6_50588087_50588294 0.69 4921507P07Rik
 RIKEN cDNA 4921507P07 gene
 8442
 0.09
chr7_45466827_45467004 0.68 Bax
 BCL2-associated X protein
 17
 0.91
chr1_89940488_89940663 0.67 Gbx2
 gastrulation brain homeobox 2
 9396
 0.19
chr6_9078648_9078799 0.66 Gm35736
 predicted gene, 35736
 68043
 0.14
chr1_39102289_39102448 0.65 Gm37091
 predicted gene, 37091
 19030
 0.18
chr3_67582623_67582799 0.64 Mfsd1
 major facilitator superfamily domain containing 1
 30
 0.96
chr5_104046470_104046646 0.64 Nudt9
 nudix (nucleoside diphosphate linked moiety X)-type motif 9
 32
 0.92
chrX_134600952_134601288 0.63 Gla
 galactosidase, alpha
 5
 0.52
chr11_120493774_120493943 0.62 Gm11788
 predicted gene 11788
 1464
 0.16
chr8_11730299_11730450 0.62 Arhgef7
 Rho guanine nucleotide exchange factor (GEF7)
 2197
 0.17
chr18_12168562_12168722 0.61 Rmc1
 regulator of MON1-CCZ1
 75
 0.96
chr7_46795972_46796137 0.60 Hps5
 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
 10
 0.51
chr13_102013412_102013573 0.58 Gm17832
 predicted gene, 17832
 93072
 0.08
chr8_124569182_124569523 0.57 Agt
 angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
 354
 0.86
chr9_40638323_40638501 0.56 Gm48284
 predicted gene, 48284
 22026
 0.1
chr10_40371945_40372096 0.56 Cdk19os
 cyclin-dependent kinase 19, opposite strand
 21917
 0.13
chr2_22998932_22999118 0.56 Gm13357
 predicted gene 13357
 20642
 0.15
chr6_121886502_121886729 0.53 Mug1
 murinoglobulin 1
 1038
 0.53
chr1_21261382_21261702 0.53 Gsta3
 glutathione S-transferase, alpha 3
 8021
 0.11
chr4_118620306_118620678 0.53 Cfap57
 cilia and flagella associated protein 57
 87
 0.76
chr8_70766641_70767079 0.52 Ifi30
 interferon gamma inducible protein 30
 197
 0.55
chr17_28517484_28517972 0.52 Fkbp5
 FK506 binding protein 5
 201
 0.84
chr18_32287263_32287414 0.52 Ercc3
 excision repair cross-complementing rodent repair deficiency, complementation group 3
 30069
 0.16
chr9_21367416_21367785 0.52 Ilf3
 interleukin enhancer binding factor 3
 271
 0.81
chr9_35125828_35126176 0.51 St3gal4
 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
 6734
 0.13
chr7_55911807_55911995 0.51 Cyfip1
 cytoplasmic FMR1 interacting protein 1
 3529
 0.15
chr18_76089817_76090552 0.50 2900057B20Rik
 RIKEN cDNA 2900057B20 gene
 8287
 0.21
chr14_57746066_57746227 0.49 Lats2
 large tumor suppressor 2
 23
 0.51
chr10_128923444_128923601 0.49 Bloc1s1
 biogenesis of lysosomal organelles complex-1, subunit 1
 2
 0.9
chr2_144369139_144369688 0.49 Kat14
 lysine acetyltransferase 14
 414
 0.43
chr5_90338287_90338461 0.48 Ankrd17
 ankyrin repeat domain 17
 1369
 0.45
chr19_41560568_41560719 0.47 Lcor
 ligand dependent nuclear receptor corepressor
 11004
 0.2
chr9_107618752_107619076 0.47 Gnai2
 guanine nucleotide binding protein (G protein), alpha inhibiting 2
 1442
 0.16
chr14_79488949_79489435 0.47 Wbp4
 WW domain binding protein 4
 7672
 0.16
chr10_75510858_75511147 0.46 Gucd1
 guanylyl cyclase domain containing 1
 262
 0.86
chr16_35769456_35769643 0.46 Slc49a4
 solute carrier family 49 member 4
 193
 0.86
chr19_54115140_54115291 0.45 Gm50186
 predicted gene, 50186
 30656
 0.18
chr13_18121582_18121957 0.45 4930448F12Rik
 RIKEN cDNA 4930448F12 gene
 21567
 0.15
chr5_66042796_66042956 0.44 Rbm47
 RNA binding motif protein 47
 11676
 0.12
chr11_52000637_52000943 0.44 Ube2b
 ubiquitin-conjugating enzyme E2B
 28
 0.52
chr10_4334368_4334532 0.42 Akap12
 A kinase (PRKA) anchor protein (gravin) 12
 95
 0.97
chr14_50924662_50925001 0.42 Osgep
 O-sialoglycoprotein endopeptidase
 1
 0.62
chr5_74401642_74401799 0.41 Scfd2
 Sec1 family domain containing 2
 3982
 0.2
chr3_153906036_153906187 0.41 Msh4
 mutS homolog 4
 27
 0.94
chr19_5610162_5610532 0.41 Kat5
 K(lysine) acetyltransferase 5
 110
 0.91
chr10_77101414_77101603 0.41 Col18a1
 collagen, type XVIII, alpha 1
 12080
 0.17
chr13_46735806_46736396 0.41 Nup153
 nucleoporin 153
 8161
 0.17
chr5_103778320_103778486 0.40 Aff1
 AF4/FMR2 family, member 1
 5956
 0.23
chr17_44350675_44350826 0.39 Gm49872
 predicted gene, 49872
 17153
 0.27
chr10_22731916_22732212 0.39 Tbpl1
 TATA box binding protein-like 1
 126
 0.9
chr15_80255398_80255563 0.38 Atf4
 activating transcription factor 4
 43
 0.95
chr19_55593151_55593306 0.37 Tcf7l2
 transcription factor 7 like 2, T cell specific, HMG box
 148592
 0.04
chr7_5062430_5062624 0.37 U2af2
 U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
 223
 0.65
chr2_84742449_84742615 0.37 Gm19426
 predicted gene, 19426
 1123
 0.24
chr17_22361357_22361742 0.36 Zfp758
 zinc finger protein 758
 27
 0.65
chr10_61143381_61143586 0.36 Sgpl1
 sphingosine phosphate lyase 1
 3415
 0.19
chr5_116419061_116419437 0.35 Hspb8
 heat shock protein 8
 3357
 0.16
chr15_97285773_97285959 0.35 Gm4383
 predicted gene 4383
 17108
 0.2
chr9_77961400_77961736 0.35 Elovl5
 ELOVL family member 5, elongation of long chain fatty acids (yeast)
 20277
 0.12
chr13_111532342_111532493 0.35 Gm15290
 predicted gene 15290
 17494
 0.13
chr15_77520533_77520827 0.34 Apol11a
 apolipoprotein L 11a
 12409
 0.11
chr1_132586686_132587343 0.34 Nfasc
 neurofascin
 126
 0.97
chr4_127077236_127077665 0.34 Zmym6
 zinc finger, MYM-type 6
 8
 0.96
chr1_13171208_13171385 0.34 Gm38376
 predicted gene, 38376
 8418
 0.16
chr12_84222439_84222605 0.34 Elmsan1
 ELM2 and Myb/SANT-like domain containing 1
 3641
 0.14
chr18_34572683_34572834 0.34 Nme5
 NME/NM23 family member 5
 6325
 0.14
chr10_128322189_128322510 0.34 Cnpy2
 canopy FGF signaling regulator 2
 110
 0.9
chr1_40085784_40085959 0.34 Gm16894
 predicted gene, 16894
 20
 0.6
chr2_130424229_130424389 0.33 Pced1a
 PC-esterase domain containing 1A
 1
 0.5
chr14_30714856_30715239 0.33 Sfmbt1
 Scm-like with four mbt domains 1
 120
 0.96
chr11_55204221_55204382 0.33 Slc36a1
 solute carrier family 36 (proton/amino acid symporter), member 1
 49
 0.97
chr6_34176282_34176719 0.33 Slc35b4
 solute carrier family 35, member B4
 470
 0.78
chr8_105773166_105773381 0.33 Gfod2
 glucose-fructose oxidoreductase domain containing 2
 14609
 0.1
chr6_91707022_91707254 0.32 Gm45828
 predicted gene 45828
 2268
 0.2
chr13_41001139_41001299 0.32 Pak1ip1
 PAK1 interacting protein 1
 19
 0.53
chr12_99208180_99208477 0.32 Gm19898
 predicted gene, 19898
 37343
 0.14
chr9_123717598_123717778 0.32 Lztfl1
 leucine zipper transcription factor-like 1
 9
 0.96
chr5_72241549_72241735 0.32 Atp10d
 ATPase, class V, type 10D
 23002
 0.17
chr7_90129909_90130310 0.32 Picalm
 phosphatidylinositol binding clathrin assembly protein
 104
 0.52
chr8_35707942_35708100 0.32 1700015I17Rik
 RIKEN cDNA 1700015I17 gene
 11928
 0.15
chr9_46036951_46037323 0.31 Sik3
 SIK family kinase 3
 24137
 0.13
chr14_41013764_41013924 0.31 Prxl2a
 peroxiredoxin like 2A
 56
 0.97
chr7_46795676_46795831 0.31 Hps5
 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
 50
 0.81
chr10_89490631_89490857 0.31 Nr1h4
 nuclear receptor subfamily 1, group H, member 4
 15905
 0.21
chr12_65036195_65036354 0.31 Prpf39
 pre-mRNA processing factor 39
 59
 0.96
chr9_43545212_43545661 0.31 Gm36855
 predicted gene, 36855
 24432
 0.17
chr3_116329378_116329892 0.30 Gm29151
 predicted gene 29151
 20468
 0.17
chr10_19015307_19015840 0.30 Tnfaip3
 tumor necrosis factor, alpha-induced protein 3
 84
 0.98
chr2_6338002_6338625 0.30 Usp6nl
 USP6 N-terminal like
 14420
 0.18
chr15_97018730_97018892 0.30 Slc38a4
 solute carrier family 38, member 4
 1140
 0.62
chr16_91255820_91256295 0.30 Gm37016
 predicted gene, 37016
 6441
 0.13
chr11_101553520_101553877 0.29 Nbr1
 NBR1, autophagy cargo receptor
 797
 0.4
chr9_87255292_87255453 0.29 Cep162
 centrosomal protein 162
 84
 0.98
chr6_128362234_128363003 0.29 Rhno1
 RAD9-HUS1-RAD1 interacting nuclear orphan 1
 39
 0.8
chr7_81004740_81004957 0.29 Gm44967
 predicted gene 44967
 10165
 0.11
chr8_84792517_84792893 0.29 Nfix
 nuclear factor I/X
 7319
 0.1
chr6_94104151_94104302 0.29 Magi1
 membrane associated guanylate kinase, WW and PDZ domain containing 1
 178799
 0.03
chr7_35802959_35803128 0.29 Zfp507
 zinc finger protein 507
 40
 0.88
chr5_87086248_87086432 0.29 Ugt2b36
 UDP glucuronosyltransferase 2 family, polypeptide B36
 4817
 0.13
chr3_89202795_89202962 0.29 Gba
 glucosidase, beta, acid
 50
 0.9
chr13_85189268_85189450 0.28 Ccnh
 cyclin H
 49
 0.98
chr6_99523725_99523876 0.28 Foxp1
 forkhead box P1
 1079
 0.57
chr11_58033500_58033932 0.28 Larp1
 La ribonucleoprotein domain family, member 1
 7897
 0.15
chr8_125669724_125669887 0.28 Map10
 microtubule-associated protein 10
 13
 0.98
chr4_135420119_135420277 0.28 Mir700
 microRNA 700
 3565
 0.12
chr4_8799595_8799756 0.28 Chd7
 chromodomain helicase DNA binding protein 7
 40647
 0.2
chr5_150774025_150774397 0.28 Pds5b
 PDS5 cohesin associated factor B
 14847
 0.15
chr9_94053316_94053467 0.28 Gm5369
 predicted gene 5369
 86071
 0.11
chr12_102878478_102878658 0.27 Btbd7
 BTB (POZ) domain containing 7
 97
 0.95
chr9_22389111_22389373 0.27 Anln
 anillin, actin binding protein
 54
 0.95
chr17_66077011_66077179 0.27 Ankrd12
 ankyrin repeat domain 12
 6
 0.96
chr13_69531330_69531517 0.27 Tent4a
 terminal nucleotidyltransferase 4A
 1009
 0.41
chr3_81386912_81387263 0.27 Gm37300
 predicted gene, 37300
 18485
 0.28
chr7_19629444_19629613 0.27 Relb
 avian reticuloendotheliosis viral (v-rel) oncogene related B
 90
 0.93
chr2_36159845_36160023 0.27 Mrrf
 mitochondrial ribosome recycling factor
 12831
 0.12
chr17_56479539_56479705 0.27 Ptprs
 protein tyrosine phosphatase, receptor type, S
 3139
 0.2
chr5_124425319_124425853 0.27 Sbno1
 strawberry notch 1
 2
 0.38
chr19_9977949_9978176 0.27 Fth1
 ferritin heavy polypeptide 1
 2536
 0.15
chr2_166126070_166126225 0.26 Sulf2
 sulfatase 2
 28276
 0.15
chr6_21823423_21823592 0.26 Tspan12
 tetraspanin 12
 28321
 0.16
chr19_46661548_46661819 0.26 Gm36602
 predicted gene, 36602
 4443
 0.14
chr14_31172747_31173116 0.26 Nisch
 nischarin
 797
 0.47
chr1_64690615_64690946 0.26 Ccnyl1
 cyclin Y-like 1
 42
 0.59
chr11_70000432_70000600 0.26 Dvl2
 dishevelled segment polarity protein 2
 79
 0.9
chr16_45158641_45158816 0.26 Slc35a5
 solute carrier family 35, member A5
 22
 0.52
chr17_24163699_24163861 0.26 Amdhd2
 amidohydrolase domain containing 2
 14
 0.94
chr5_146792230_146792423 0.26 Usp12
 ubiquitin specific peptidase 12
 2680
 0.19
chr4_139109272_139109459 0.26 Micos10
 mitochondrial contact site and cristae organizing system subunit 10
 1878
 0.25
chr3_121214666_121215038 0.25 Tlcd4
 TLC domain containing 4
 16681
 0.14
chr16_92826008_92826183 0.25 Runx1
 runt related transcription factor 1
 21
 0.98
chr10_95685288_95685475 0.25 Anapc15-ps
 anaphase promoting complex C subunit 15, pseudogene
 11930
 0.11
chr17_32943503_32943656 0.25 Cyp4f13
 cytochrome P450, family 4, subfamily f, polypeptide 13
 3756
 0.12
chr5_87562697_87562848 0.24 Sult1d1
 sulfotransferase family 1D, member 1
 2581
 0.17
chr17_65886042_65886193 0.24 Gm49870
 predicted gene, 49870
 224
 0.43
chr11_5917118_5917412 0.24 Gm11967
 predicted gene 11967
 1950
 0.2
chr6_6577877_6578251 0.24 Sem1
 SEM1, 26S proteasome complex subunit
 594
 0.79
chr5_72259392_72259543 0.24 Atp10d
 ATPase, class V, type 10D
 5177
 0.21
chr1_130826570_130826742 0.23 Pigr
 polymeric immunoglobulin receptor
 28
 0.96
chr5_97090249_97090465 0.23 Paqr3
 progestin and adipoQ receptor family member III
 7414
 0.19
chr16_97610441_97610883 0.23 Tmprss2
 transmembrane protease, serine 2
 307
 0.91
chr10_81176435_81176616 0.23 Eef2
 eukaryotic translation elongation factor 2
 106
 0.89
chr19_42779893_42780058 0.23 Hps1
 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
 1
 0.95
chr2_25356295_25356463 0.23 Dpp7
 dipeptidylpeptidase 7
 20
 0.93
chr7_126583293_126583667 0.23 Cln3
 ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
 43
 0.92
chr14_61680870_61681697 0.23 Gm37472
 predicted gene, 37472
 211
 0.83
chr15_99723268_99723456 0.23 Gm16537
 predicted gene 16537
 1112
 0.24
chr14_63066975_63067226 0.23 Defb42
 defensin beta 42
 12027
 0.11
chr16_35770249_35770414 0.23 Hspbap1
 Hspb associated protein 1
 44
 0.94
chr3_95754384_95754717 0.23 Tars2
 threonyl-tRNA synthetase 2, mitochondrial (putative)
 78
 0.94
chr4_138981088_138981239 0.23 Tmco4
 transmembrane and coiled-coil domains 4
 8254
 0.16
chr13_35036409_35036560 0.22 Gm48626
 predicted gene, 48626
 4538
 0.14
chr3_10439906_10440215 0.22 Snx16
 sorting nexin 16
 27
 0.98
chr5_143622347_143622510 0.22 Cyth3
 cytohesin 3
 19
 0.98
chr4_59254499_59254704 0.22 Gm12596
 predicted gene 12596
 5450
 0.21
chr7_27196105_27196414 0.22 Snrpa
 small nuclear ribonucleoprotein polypeptide A
 12
 0.86
chr9_107666466_107666787 0.22 Slc38a3
 solute carrier family 38, member 3
 748
 0.41
chr8_93234472_93234646 0.22 Ces1e
 carboxylesterase 1E
 4940
 0.15
chr2_11441861_11442106 0.22 Gm13296
 predicted gene 13296
 21759
 0.11
chr14_52197392_52197558 0.22 Gm26590
 predicted gene, 26590
 27
 0.52
chr1_106178120_106178315 0.22 Phlpp1
 PH domain and leucine rich repeat protein phosphatase 1
 6465
 0.19
chr8_11477778_11477940 0.21 E230013L22Rik
 RIKEN cDNA E230013L22 gene
 70
 0.92
chr18_6136125_6136303 0.21 Arhgap12
 Rho GTPase activating protein 12
 116
 0.97
chr8_48740269_48740425 0.21 Tenm3
 teneurin transmembrane protein 3
 65657
 0.13
chr11_78964690_78964876 0.21 Lgals9
 lectin, galactose binding, soluble 9
 5547
 0.2
chr2_30133618_30133793 0.21 Tbc1d13
 TBC1 domain family, member 13
 41
 0.95
chr14_25396821_25396972 0.21 Gm26660
 predicted gene, 26660
 17287
 0.16
chr13_93612829_93612980 0.21 Gm15622
 predicted gene 15622
 12478
 0.16
chr3_30792776_30792939 0.21 Sec62
 SEC62 homolog (S. cerevisiae)
 18
 0.93
chr3_107278861_107279068 0.21 Lamtor5
 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
 35
 0.97
chr14_59200883_59201288 0.21 Rcbtb1
 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
 124
 0.96
chr11_50431056_50431230 0.21 Rufy1
 RUN and FYVE domain containing 1
 18
 0.98
chr8_85025239_85025399 0.21 Asna1
 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
 38
 0.91
chr12_28899893_28900063 0.21 Gm31508
 predicted gene, 31508
 10251
 0.18
chr2_152729731_152729890 0.20 Id1
 inhibitor of DNA binding 1, HLH protein
 6441
 0.11
chr4_134468257_134468415 0.20 Stmn1
 stathmin 1
 16
 0.5
chr14_40934609_40934760 0.20 Tspan14
 tetraspanin 14
 363
 0.88
chr3_152396303_152396479 0.20 Zzz3
 zinc finger, ZZ domain containing 3
 259
 0.84
chr17_25240096_25240257 0.20 Tsr3
 TSR3 20S rRNA accumulation
 6
 0.51

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Bhlhe40

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2 0.7 GO:0006808 regulation of nitrogen utilization(GO:0006808)
0.2 0.5 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.6 GO:0009169 ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.6 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.4 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.3 GO:0046075 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.1 0.6 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.3 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.1 0.3 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.3 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.1 0.2 GO:0071336 regulation of hair follicle cell proliferation(GO:0071336)
0.1 0.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.2 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.1 0.2 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.1 0.4 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.2 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.1 0.2 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 0.2 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 0.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.2 GO:0051182 coenzyme transport(GO:0051182)
0.1 0.2 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.2 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.1 0.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.2 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.3 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0 0.1 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0 0.2 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0 0.3 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.3 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0 0.3 GO:1903441 protein localization to ciliary membrane(GO:1903441)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.4 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.4 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.4 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.0 GO:0090148 membrane fission(GO:0090148)
0.0 0.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:0015744 succinate transport(GO:0015744)
0.0 0.1 GO:0034182 regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.1 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.0 0.1 GO:0006714 sesquiterpenoid metabolic process(GO:0006714)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.0 GO:0043321 regulation of natural killer cell degranulation(GO:0043321)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.4 GO:0006298 mismatch repair(GO:0006298)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.0 0.1 GO:0006407 rRNA export from nucleus(GO:0006407)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.0 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.0 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.0 GO:2001025 positive regulation of response to drug(GO:2001025)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.0 GO:0038027 apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 0.0 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.0 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.0 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.4 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.0 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.1 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.1 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.0 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.2 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0097237 cellular response to toxic substance(GO:0097237)
0.0 0.2 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.0 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.0 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
0.0 0.0 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 0.0 GO:0006597 spermine biosynthetic process(GO:0006597)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 0.5 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.8 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.4 GO:0097413 Lewy body(GO:0097413)
0.1 0.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.2 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.1 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.5 GO:0000243 commitment complex(GO:0000243)
0.1 0.5 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.2 GO:0032010 phagolysosome(GO:0032010)
0.1 0.2 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.3 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.6 GO:0031082 BLOC complex(GO:0031082)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.0 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.2 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.0 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.5 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.6 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.1 0.5 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.8 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.3 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.2 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.1 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.2 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.9 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.0 GO:0016414 O-octanoyltransferase activity(GO:0016414)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.0 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.1 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0015186 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.2 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.0 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.0 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.0 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.0 PID ATM PATHWAY ATM pathway
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 PID P73PATHWAY p73 transcription factor network
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.1 ST G ALPHA I PATHWAY G alpha i Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation