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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Bhlhe40

Z-value: 1.50

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Transcription factors associated with Bhlhe40

Gene Symbol	Gene ID	Gene Info
Bhlhe40 Ensembl NCBI MGI UniProt	ENSMUSG00000030103.5	Bhlhe40

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Bhlhe40	chr6_108709314_108709465	46343	0.116291	0.73	9.9e-02	Click!
Bhlhe40	chr6_108668460_108668647	5507	0.177493	-0.71	1.2e-01	Click!
Bhlhe40	chr6_108704850_108705008	41883	0.123574	-0.69	1.3e-01	Click!
Bhlhe40	chr6_108670913_108671087	7954	0.168584	-0.65	1.6e-01	Click!
Bhlhe40	chr6_108664929_108665106	1971	0.278122	0.65	1.6e-01	Click!

Activity of the Bhlhe40 motif across conditions

Conditions sorted by the z-value of the Bhlhe40 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_93323421_93323587	1.31	Ccng2	cyclin G2	54796	0.1
chr5_25015695_25015994	1.25	Prkag2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	20091	0.17
chr19_4201629_4201786	1.07	Rad9a	RAD9 checkpoint clamp component A	45	0.5
chr19_7240751_7240928	1.03	Naa40	N(alpha)-acetyltransferase 40, NatD catalytic subunit	195	0.89
chr7_81002031_81002182	0.97	Gm44967	predicted gene 44967	7423	0.11
chr19_23074772_23074923	0.95	C330002G04Rik	RIKEN cDNA C330002G04 gene	1006	0.54
chr3_121735675_121736039	0.95	F3	coagulation factor III	6310	0.11
chr4_149426608_149426780	0.91	Ube4b	ubiquitination factor E4B	55	0.96
chr2_103592357_103592552	0.90	Abtb2	ankyrin repeat and BTB (POZ) domain containing 2	26144	0.17
chr13_38849595_38849761	0.86	Gm46392	predicted gene, 46392	12052	0.18
chr6_115838132_115838303	0.85	Efcab12	EF-hand calcium binding domain 12	195	0.88
chr5_136170628_136170833	0.82	Orai2	ORAI calcium release-activated calcium modulator 2	17	0.96
chr17_24205766_24206106	0.81	Tbc1d24	TBC1 domain family, member 24	374	0.68
chr9_44079482_44079643	0.81	Usp2	ubiquitin specific peptidase 2	5377	0.08
chr5_115010965_115011126	0.80	Sppl3	signal peptide peptidase 3	92	0.94
chr17_12769661_12769836	0.78	Igf2r	insulin-like growth factor 2 receptor	84	0.95
chr10_43742623_43743061	0.76	Gm40634	predicted gene, 40634	245	0.89
chr9_49365685_49366095	0.75	Drd2	dopamine receptor D2	25263	0.2
chr1_143739744_143740319	0.73	Glrx2	glutaredoxin 2 (thioltransferase)	344	0.84
chr11_117780625_117780787	0.72	Tmc6	transmembrane channel-like gene family 6	48	0.93
chr19_30096271_30096642	0.71	Uhrf2	ubiquitin-like, containing PHD and RING finger domains 2	4495	0.24
chr15_58972603_58972890	0.70	Mtss1	MTSS I-BAR domain containing 1	207	0.92
chr6_50588087_50588294	0.69	4921507P07Rik	RIKEN cDNA 4921507P07 gene	8442	0.09
chr7_45466827_45467004	0.68	Bax	BCL2-associated X protein	17	0.91
chr1_89940488_89940663	0.67	Gbx2	gastrulation brain homeobox 2	9396	0.19
chr6_9078648_9078799	0.66	Gm35736	predicted gene, 35736	68043	0.14
chr1_39102289_39102448	0.65	Gm37091	predicted gene, 37091	19030	0.18
chr3_67582623_67582799	0.64	Mfsd1	major facilitator superfamily domain containing 1	30	0.96
chr5_104046470_104046646	0.64	Nudt9	nudix (nucleoside diphosphate linked moiety X)-type motif 9	32	0.92
chrX_134600952_134601288	0.63	Gla	galactosidase, alpha	5	0.52
chr11_120493774_120493943	0.62	Gm11788	predicted gene 11788	1464	0.16
chr8_11730299_11730450	0.62	Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	2197	0.17
chr18_12168562_12168722	0.61	Rmc1	regulator of MON1-CCZ1	75	0.96
chr7_46795972_46796137	0.60	Hps5	HPS5, biogenesis of lysosomal organelles complex 2 subunit 2	10	0.51
chr13_102013412_102013573	0.58	Gm17832	predicted gene, 17832	93072	0.08
chr8_124569182_124569523	0.57	Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	354	0.86
chr9_40638323_40638501	0.56	Gm48284	predicted gene, 48284	22026	0.1
chr10_40371945_40372096	0.56	Cdk19os	cyclin-dependent kinase 19, opposite strand	21917	0.13
chr2_22998932_22999118	0.56	Gm13357	predicted gene 13357	20642	0.15
chr6_121886502_121886729	0.53	Mug1	murinoglobulin 1	1038	0.53
chr1_21261382_21261702	0.53	Gsta3	glutathione S-transferase, alpha 3	8021	0.11
chr4_118620306_118620678	0.53	Cfap57	cilia and flagella associated protein 57	87	0.76
chr8_70766641_70767079	0.52	Ifi30	interferon gamma inducible protein 30	197	0.55
chr17_28517484_28517972	0.52	Fkbp5	FK506 binding protein 5	201	0.84
chr18_32287263_32287414	0.52	Ercc3	excision repair cross-complementing rodent repair deficiency, complementation group 3	30069	0.16
chr9_21367416_21367785	0.52	Ilf3	interleukin enhancer binding factor 3	271	0.81
chr9_35125828_35126176	0.51	St3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	6734	0.13
chr7_55911807_55911995	0.51	Cyfip1	cytoplasmic FMR1 interacting protein 1	3529	0.15
chr18_76089817_76090552	0.50	2900057B20Rik	RIKEN cDNA 2900057B20 gene	8287	0.21
chr14_57746066_57746227	0.49	Lats2	large tumor suppressor 2	23	0.51
chr10_128923444_128923601	0.49	Bloc1s1	biogenesis of lysosomal organelles complex-1, subunit 1	2	0.9
chr2_144369139_144369688	0.49	Kat14	lysine acetyltransferase 14	414	0.43
chr5_90338287_90338461	0.48	Ankrd17	ankyrin repeat domain 17	1369	0.45
chr19_41560568_41560719	0.47	Lcor	ligand dependent nuclear receptor corepressor	11004	0.2
chr9_107618752_107619076	0.47	Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	1442	0.16
chr14_79488949_79489435	0.47	Wbp4	WW domain binding protein 4	7672	0.16
chr10_75510858_75511147	0.46	Gucd1	guanylyl cyclase domain containing 1	262	0.86
chr16_35769456_35769643	0.46	Slc49a4	solute carrier family 49 member 4	193	0.86
chr19_54115140_54115291	0.45	Gm50186	predicted gene, 50186	30656	0.18
chr13_18121582_18121957	0.45	4930448F12Rik	RIKEN cDNA 4930448F12 gene	21567	0.15
chr5_66042796_66042956	0.44	Rbm47	RNA binding motif protein 47	11676	0.12
chr11_52000637_52000943	0.44	Ube2b	ubiquitin-conjugating enzyme E2B	28	0.52
chr10_4334368_4334532	0.42	Akap12	A kinase (PRKA) anchor protein (gravin) 12	95	0.97
chr14_50924662_50925001	0.42	Osgep	O-sialoglycoprotein endopeptidase	1	0.62
chr5_74401642_74401799	0.41	Scfd2	Sec1 family domain containing 2	3982	0.2
chr3_153906036_153906187	0.41	Msh4	mutS homolog 4	27	0.94
chr19_5610162_5610532	0.41	Kat5	K(lysine) acetyltransferase 5	110	0.91
chr10_77101414_77101603	0.41	Col18a1	collagen, type XVIII, alpha 1	12080	0.17
chr13_46735806_46736396	0.41	Nup153	nucleoporin 153	8161	0.17
chr5_103778320_103778486	0.40	Aff1	AF4/FMR2 family, member 1	5956	0.23
chr17_44350675_44350826	0.39	Gm49872	predicted gene, 49872	17153	0.27
chr10_22731916_22732212	0.39	Tbpl1	TATA box binding protein-like 1	126	0.9
chr15_80255398_80255563	0.38	Atf4	activating transcription factor 4	43	0.95
chr19_55593151_55593306	0.37	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box	148592	0.04
chr7_5062430_5062624	0.37	U2af2	U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2	223	0.65
chr2_84742449_84742615	0.37	Gm19426	predicted gene, 19426	1123	0.24
chr17_22361357_22361742	0.36	Zfp758	zinc finger protein 758	27	0.65
chr10_61143381_61143586	0.36	Sgpl1	sphingosine phosphate lyase 1	3415	0.19
chr5_116419061_116419437	0.35	Hspb8	heat shock protein 8	3357	0.16
chr15_97285773_97285959	0.35	Gm4383	predicted gene 4383	17108	0.2
chr9_77961400_77961736	0.35	Elovl5	ELOVL family member 5, elongation of long chain fatty acids (yeast)	20277	0.12
chr13_111532342_111532493	0.35	Gm15290	predicted gene 15290	17494	0.13
chr15_77520533_77520827	0.34	Apol11a	apolipoprotein L 11a	12409	0.11
chr1_132586686_132587343	0.34	Nfasc	neurofascin	126	0.97
chr4_127077236_127077665	0.34	Zmym6	zinc finger, MYM-type 6	8	0.96
chr1_13171208_13171385	0.34	Gm38376	predicted gene, 38376	8418	0.16
chr12_84222439_84222605	0.34	Elmsan1	ELM2 and Myb/SANT-like domain containing 1	3641	0.14
chr18_34572683_34572834	0.34	Nme5	NME/NM23 family member 5	6325	0.14
chr10_128322189_128322510	0.34	Cnpy2	canopy FGF signaling regulator 2	110	0.9
chr1_40085784_40085959	0.34	Gm16894	predicted gene, 16894	20	0.6
chr2_130424229_130424389	0.33	Pced1a	PC-esterase domain containing 1A	1	0.5
chr14_30714856_30715239	0.33	Sfmbt1	Scm-like with four mbt domains 1	120	0.96
chr11_55204221_55204382	0.33	Slc36a1	solute carrier family 36 (proton/amino acid symporter), member 1	49	0.97
chr6_34176282_34176719	0.33	Slc35b4	solute carrier family 35, member B4	470	0.78
chr8_105773166_105773381	0.33	Gfod2	glucose-fructose oxidoreductase domain containing 2	14609	0.1
chr6_91707022_91707254	0.32	Gm45828	predicted gene 45828	2268	0.2
chr13_41001139_41001299	0.32	Pak1ip1	PAK1 interacting protein 1	19	0.53
chr12_99208180_99208477	0.32	Gm19898	predicted gene, 19898	37343	0.14
chr9_123717598_123717778	0.32	Lztfl1	leucine zipper transcription factor-like 1	9	0.96
chr5_72241549_72241735	0.32	Atp10d	ATPase, class V, type 10D	23002	0.17
chr7_90129909_90130310	0.32	Picalm	phosphatidylinositol binding clathrin assembly protein	104	0.52
chr8_35707942_35708100	0.32	1700015I17Rik	RIKEN cDNA 1700015I17 gene	11928	0.15
chr9_46036951_46037323	0.31	Sik3	SIK family kinase 3	24137	0.13
chr14_41013764_41013924	0.31	Prxl2a	peroxiredoxin like 2A	56	0.97
chr7_46795676_46795831	0.31	Hps5	HPS5, biogenesis of lysosomal organelles complex 2 subunit 2	50	0.81
chr10_89490631_89490857	0.31	Nr1h4	nuclear receptor subfamily 1, group H, member 4	15905	0.21
chr12_65036195_65036354	0.31	Prpf39	pre-mRNA processing factor 39	59	0.96
chr9_43545212_43545661	0.31	Gm36855	predicted gene, 36855	24432	0.17
chr3_116329378_116329892	0.30	Gm29151	predicted gene 29151	20468	0.17
chr10_19015307_19015840	0.30	Tnfaip3	tumor necrosis factor, alpha-induced protein 3	84	0.98
chr2_6338002_6338625	0.30	Usp6nl	USP6 N-terminal like	14420	0.18
chr15_97018730_97018892	0.30	Slc38a4	solute carrier family 38, member 4	1140	0.62
chr16_91255820_91256295	0.30	Gm37016	predicted gene, 37016	6441	0.13
chr11_101553520_101553877	0.29	Nbr1	NBR1, autophagy cargo receptor	797	0.4
chr9_87255292_87255453	0.29	Cep162	centrosomal protein 162	84	0.98
chr6_128362234_128363003	0.29	Rhno1	RAD9-HUS1-RAD1 interacting nuclear orphan 1	39	0.8
chr7_81004740_81004957	0.29	Gm44967	predicted gene 44967	10165	0.11
chr8_84792517_84792893	0.29	Nfix	nuclear factor I/X	7319	0.1
chr6_94104151_94104302	0.29	Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	178799	0.03
chr7_35802959_35803128	0.29	Zfp507	zinc finger protein 507	40	0.88
chr5_87086248_87086432	0.29	Ugt2b36	UDP glucuronosyltransferase 2 family, polypeptide B36	4817	0.13
chr3_89202795_89202962	0.29	Gba	glucosidase, beta, acid	50	0.9
chr13_85189268_85189450	0.28	Ccnh	cyclin H	49	0.98
chr6_99523725_99523876	0.28	Foxp1	forkhead box P1	1079	0.57
chr11_58033500_58033932	0.28	Larp1	La ribonucleoprotein domain family, member 1	7897	0.15
chr8_125669724_125669887	0.28	Map10	microtubule-associated protein 10	13	0.98
chr4_135420119_135420277	0.28	Mir700	microRNA 700	3565	0.12
chr4_8799595_8799756	0.28	Chd7	chromodomain helicase DNA binding protein 7	40647	0.2
chr5_150774025_150774397	0.28	Pds5b	PDS5 cohesin associated factor B	14847	0.15
chr9_94053316_94053467	0.28	Gm5369	predicted gene 5369	86071	0.11
chr12_102878478_102878658	0.27	Btbd7	BTB (POZ) domain containing 7	97	0.95
chr9_22389111_22389373	0.27	Anln	anillin, actin binding protein	54	0.95
chr17_66077011_66077179	0.27	Ankrd12	ankyrin repeat domain 12	6	0.96
chr13_69531330_69531517	0.27	Tent4a	terminal nucleotidyltransferase 4A	1009	0.41
chr3_81386912_81387263	0.27	Gm37300	predicted gene, 37300	18485	0.28
chr7_19629444_19629613	0.27	Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	90	0.93
chr2_36159845_36160023	0.27	Mrrf	mitochondrial ribosome recycling factor	12831	0.12
chr17_56479539_56479705	0.27	Ptprs	protein tyrosine phosphatase, receptor type, S	3139	0.2
chr5_124425319_124425853	0.27	Sbno1	strawberry notch 1	2	0.38
chr19_9977949_9978176	0.27	Fth1	ferritin heavy polypeptide 1	2536	0.15
chr2_166126070_166126225	0.26	Sulf2	sulfatase 2	28276	0.15
chr6_21823423_21823592	0.26	Tspan12	tetraspanin 12	28321	0.16
chr19_46661548_46661819	0.26	Gm36602	predicted gene, 36602	4443	0.14
chr14_31172747_31173116	0.26	Nisch	nischarin	797	0.47
chr1_64690615_64690946	0.26	Ccnyl1	cyclin Y-like 1	42	0.59
chr11_70000432_70000600	0.26	Dvl2	dishevelled segment polarity protein 2	79	0.9
chr16_45158641_45158816	0.26	Slc35a5	solute carrier family 35, member A5	22	0.52
chr17_24163699_24163861	0.26	Amdhd2	amidohydrolase domain containing 2	14	0.94
chr5_146792230_146792423	0.26	Usp12	ubiquitin specific peptidase 12	2680	0.19
chr4_139109272_139109459	0.26	Micos10	mitochondrial contact site and cristae organizing system subunit 10	1878	0.25
chr3_121214666_121215038	0.25	Tlcd4	TLC domain containing 4	16681	0.14
chr16_92826008_92826183	0.25	Runx1	runt related transcription factor 1	21	0.98
chr10_95685288_95685475	0.25	Anapc15-ps	anaphase promoting complex C subunit 15, pseudogene	11930	0.11
chr17_32943503_32943656	0.25	Cyp4f13	cytochrome P450, family 4, subfamily f, polypeptide 13	3756	0.12
chr5_87562697_87562848	0.24	Sult1d1	sulfotransferase family 1D, member 1	2581	0.17
chr17_65886042_65886193	0.24	Gm49870	predicted gene, 49870	224	0.43
chr11_5917118_5917412	0.24	Gm11967	predicted gene 11967	1950	0.2
chr6_6577877_6578251	0.24	Sem1	SEM1, 26S proteasome complex subunit	594	0.79
chr5_72259392_72259543	0.24	Atp10d	ATPase, class V, type 10D	5177	0.21
chr1_130826570_130826742	0.23	Pigr	polymeric immunoglobulin receptor	28	0.96
chr5_97090249_97090465	0.23	Paqr3	progestin and adipoQ receptor family member III	7414	0.19
chr16_97610441_97610883	0.23	Tmprss2	transmembrane protease, serine 2	307	0.91
chr10_81176435_81176616	0.23	Eef2	eukaryotic translation elongation factor 2	106	0.89
chr19_42779893_42780058	0.23	Hps1	HPS1, biogenesis of lysosomal organelles complex 3 subunit 1	1	0.95
chr2_25356295_25356463	0.23	Dpp7	dipeptidylpeptidase 7	20	0.93
chr7_126583293_126583667	0.23	Cln3	ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)	43	0.92
chr14_61680870_61681697	0.23	Gm37472	predicted gene, 37472	211	0.83
chr15_99723268_99723456	0.23	Gm16537	predicted gene 16537	1112	0.24
chr14_63066975_63067226	0.23	Defb42	defensin beta 42	12027	0.11
chr16_35770249_35770414	0.23	Hspbap1	Hspb associated protein 1	44	0.94
chr3_95754384_95754717	0.23	Tars2	threonyl-tRNA synthetase 2, mitochondrial (putative)	78	0.94
chr4_138981088_138981239	0.23	Tmco4	transmembrane and coiled-coil domains 4	8254	0.16
chr13_35036409_35036560	0.22	Gm48626	predicted gene, 48626	4538	0.14
chr3_10439906_10440215	0.22	Snx16	sorting nexin 16	27	0.98
chr5_143622347_143622510	0.22	Cyth3	cytohesin 3	19	0.98
chr4_59254499_59254704	0.22	Gm12596	predicted gene 12596	5450	0.21
chr7_27196105_27196414	0.22	Snrpa	small nuclear ribonucleoprotein polypeptide A	12	0.86
chr9_107666466_107666787	0.22	Slc38a3	solute carrier family 38, member 3	748	0.41
chr8_93234472_93234646	0.22	Ces1e	carboxylesterase 1E	4940	0.15
chr2_11441861_11442106	0.22	Gm13296	predicted gene 13296	21759	0.11
chr14_52197392_52197558	0.22	Gm26590	predicted gene, 26590	27	0.52
chr1_106178120_106178315	0.22	Phlpp1	PH domain and leucine rich repeat protein phosphatase 1	6465	0.19
chr8_11477778_11477940	0.21	E230013L22Rik	RIKEN cDNA E230013L22 gene	70	0.92
chr18_6136125_6136303	0.21	Arhgap12	Rho GTPase activating protein 12	116	0.97
chr8_48740269_48740425	0.21	Tenm3	teneurin transmembrane protein 3	65657	0.13
chr11_78964690_78964876	0.21	Lgals9	lectin, galactose binding, soluble 9	5547	0.2
chr2_30133618_30133793	0.21	Tbc1d13	TBC1 domain family, member 13	41	0.95
chr14_25396821_25396972	0.21	Gm26660	predicted gene, 26660	17287	0.16
chr13_93612829_93612980	0.21	Gm15622	predicted gene 15622	12478	0.16
chr3_30792776_30792939	0.21	Sec62	SEC62 homolog (S. cerevisiae)	18	0.93
chr3_107278861_107279068	0.21	Lamtor5	late endosomal/lysosomal adaptor, MAPK and MTOR activator 5	35	0.97
chr14_59200883_59201288	0.21	Rcbtb1	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1	124	0.96
chr11_50431056_50431230	0.21	Rufy1	RUN and FYVE domain containing 1	18	0.98
chr8_85025239_85025399	0.21	Asna1	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)	38	0.91
chr12_28899893_28900063	0.21	Gm31508	predicted gene, 31508	10251	0.18
chr2_152729731_152729890	0.20	Id1	inhibitor of DNA binding 1, HLH protein	6441	0.11
chr4_134468257_134468415	0.20	Stmn1	stathmin 1	16	0.5
chr14_40934609_40934760	0.20	Tspan14	tetraspanin 14	363	0.88
chr3_152396303_152396479	0.20	Zzz3	zinc finger, ZZ domain containing 3	259	0.84
chr17_25240096_25240257	0.20	Tsr3	TSR3 20S rRNA accumulation	6	0.51

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Bhlhe40

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2	0.7	GO:0006808	regulation of nitrogen utilization(GO:0006808)
0.2	0.5	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1	0.6	GO:0009169	ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.6	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.4	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1	0.3	GO:0046075	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.1	0.6	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.1	0.3	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.1	0.3	GO:0001827	inner cell mass cell fate commitment(GO:0001827)
0.1	0.3	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1	0.3	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1	0.3	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
0.1	0.2	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336)
0.1	0.8	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1	0.2	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.1	0.2	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.1	0.4	GO:0015808	L-alanine transport(GO:0015808)
0.1	0.2	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
0.1	0.2	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1	0.2	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.1	0.5	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1	0.2	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1	0.2	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1	0.3	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.1	0.3	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.1	0.2	GO:0051182	coenzyme transport(GO:0051182)
0.1	0.2	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1	0.2	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.1	0.2	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.1	0.2	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
0.1	0.3	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0	0.1	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0	0.2	GO:1904684	negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0	0.3	GO:0000022	mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0	0.1	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.0	0.3	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0	0.2	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.3	GO:1903441	protein localization to ciliary membrane(GO:1903441)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.3	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.2	GO:0051122	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0	0.2	GO:0048069	eye pigmentation(GO:0048069)
0.0	0.1	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.0	0.1	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.2	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.4	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.4	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	0.4	GO:0099514	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0	0.1	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.4	GO:0061462	protein localization to lysosome(GO:0061462)
0.0	0.2	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.2	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0090148	membrane fission(GO:0090148)
0.0	0.1	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.0	0.1	GO:1902416	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0	0.1	GO:0072429	response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0	0.1	GO:0015744	succinate transport(GO:0015744)
0.0	0.1	GO:0034182	regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
0.0	0.1	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	0.1	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	0.1	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.0	0.1	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:2000015	regulation of determination of dorsal identity(GO:2000015)
0.0	0.4	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.0	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.0	0.2	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.0	0.4	GO:0006298	mismatch repair(GO:0006298)
0.0	0.1	GO:0034473	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0	0.1	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.0	0.1	GO:0006407	rRNA export from nucleus(GO:0006407)
0.0	0.1	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.1	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0051105	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.1	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.4	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	0.1	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:0034287	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.0	GO:0006210	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.0	0.0	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.0	0.0	GO:2001025	positive regulation of response to drug(GO:2001025)
0.0	0.1	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0	0.0	GO:0038027	apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.0	0.8	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.0	0.1	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.0	0.0	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.1	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.0	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.0	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.0	0.4	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.0	GO:0060988	lipid tube assembly(GO:0060988)
0.0	0.1	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.1	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.0	0.1	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.0	0.1	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.1	GO:0042256	mature ribosome assembly(GO:0042256)
0.0	0.1	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.0	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.0	GO:0040023	establishment of nucleus localization(GO:0040023)
0.0	0.2	GO:0097352	autophagosome maturation(GO:0097352)
0.0	0.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.2	GO:0097237	cellular response to toxic substance(GO:0097237)
0.0	0.2	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.0	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.1	GO:0072673	lamellipodium morphogenesis(GO:0072673)
0.0	0.0	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
0.0	0.0	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.0	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.0	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.0	GO:0006597	spermine biosynthetic process(GO:0006597)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.2	0.5	GO:0031084	BLOC-2 complex(GO:0031084)
0.1	0.8	GO:0071556	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1	0.4	GO:0097413	Lewy body(GO:0097413)
0.1	0.3	GO:0097454	Schwann cell microvillus(GO:0097454)
0.1	0.3	GO:0005879	axonemal microtubule(GO:0005879)
0.1	0.5	GO:0030896	checkpoint clamp complex(GO:0030896)
0.1	0.4	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.2	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.1	0.3	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.1	0.5	GO:0000243	commitment complex(GO:0000243)
0.1	0.5	GO:0000439	core TFIIH complex(GO:0000439)
0.1	0.3	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	0.8	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.3	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	0.2	GO:0032010	phagolysosome(GO:0032010)
0.1	0.2	GO:0097418	neurofibrillary tangle(GO:0097418)
0.1	0.2	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.1	0.3	GO:0043202	lysosomal lumen(GO:0043202)
0.1	0.3	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.2	GO:0033503	HULC complex(GO:0033503)
0.0	0.6	GO:0031082	BLOC complex(GO:0031082)
0.0	0.1	GO:1990812	growth cone filopodium(GO:1990812)
0.0	0.3	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.2	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.2	GO:0033263	CORVET complex(GO:0033263)
0.0	0.3	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.1	GO:0000322	storage vacuole(GO:0000322)
0.0	0.2	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.2	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0097422	tubular endosome(GO:0097422)
0.0	0.0	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.1	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0031209	SCAR complex(GO:0031209)
0.0	0.1	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.2	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.2	GO:0043194	axon initial segment(GO:0043194)
0.0	0.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	0.2	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.1	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.0	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.5	GO:0000795	synaptonemal complex(GO:0000795)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0061617	MICOS complex(GO:0061617)
0.0	0.1	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.0	GO:0032299	ribonuclease H2 complex(GO:0032299)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0051434	BH3 domain binding(GO:0051434)
0.1	0.6	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.1	0.5	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.1	0.7	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.8	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1	0.3	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1	0.8	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1	0.2	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.1	0.3	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1	0.4	GO:0016936	galactoside binding(GO:0016936)
0.1	0.8	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	0.2	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.1	0.2	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1	0.3	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	0.2	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.5	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0	0.2	GO:0030619	U1 snRNA binding(GO:0030619)
0.0	0.1	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.2	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.4	GO:0030983	mismatched DNA binding(GO:0030983)
0.0	0.6	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.2	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.1	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.2	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.9	GO:0015036	disulfide oxidoreductase activity(GO:0015036)
0.0	0.3	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	1.0	GO:0016414	O-octanoyltransferase activity(GO:0016414)
0.0	0.6	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.4	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.3	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.2	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.1	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.2	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021)
0.0	0.2	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.1	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0	0.2	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0	0.1	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0	0.4	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0015141	succinate transmembrane transporter activity(GO:0015141)
0.0	0.1	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.1	GO:0015186	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.1	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.0	0.1	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.3	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0016015	morphogen activity(GO:0016015)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.2	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.0	GO:1904288	BAT3 complex binding(GO:1904288)
0.0	0.3	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.0	GO:0005350	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.0	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.0	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.0	GO:0015216	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.1	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.0	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0000182	rDNA binding(GO:0000182)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0005351	sugar:proton symporter activity(GO:0005351)
0.0	0.1	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	1.0	PID ATM PATHWAY	ATM pathway
0.0	0.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.5	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.3	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.6	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.8	PID P73PATHWAY	p73 transcription factor network
0.0	0.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.3	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.1	ST G ALPHA I PATHWAY	G alpha i Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.7	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
1.4	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.8	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.7	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.4	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.5	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.3	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.3	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.2	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation