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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Cdc5l

Z-value: 1.96

Motif logo

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Transcription factors associated with Cdc5l

Gene Symbol Gene ID Gene Info
Cdc5l
ENSMUSG00000023932.8 cell division cycle 5-like (S. pombe)

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr17_45432981_45433132Cdc5l4850.473916-0.815.0e-02Click!
chr17_45322913_45323086Cdc5l926850.062487-0.767.7e-02Click!
chr17_45402203_45402541Cdc5l133120.1647630.532.8e-01Click!
chr17_45402856_45403089Cdc5l127120.1652370.522.9e-01Click!
chr17_45433278_45433437Cdc5l1840.565485-0.513.0e-01Click!

Activity of the Cdc5l motif across conditions

Conditions sorted by the z-value of the Cdc5l motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr13_96674138_96674322 2.44 Hmgcr
 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
 3294
 0.19
chr8_40878264_40878415 1.98 Slc7a2
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
 3391
 0.2
chr9_19622407_19622600 1.79 Zfp317
 zinc finger protein 317
 199
 0.91
chr2_65167070_65167237 1.60 Cobll1
 Cobl-like 1
 61294
 0.12
chr19_36263973_36264136 1.60 Gm32027
 predicted gene, 32027
 383
 0.85
chr7_73542824_73542975 1.46 Chd2
 chromodomain helicase DNA binding protein 2
 1069
 0.35
chr11_16803107_16803282 1.33 Egfros
 epidermal growth factor receptor, opposite strand
 27508
 0.17
chr6_119883269_119883450 1.27 Gm15532
 predicted gene 15532
 9561
 0.15
chr1_172159886_172160228 1.23 Dcaf8
 DDB1 and CUL4 associated factor 8
 11109
 0.1
chr2_52575707_52576080 1.20 Cacnb4
 calcium channel, voltage-dependent, beta 4 subunit
 17326
 0.18
chr19_40153581_40153732 1.19 Cyp2c70
 cytochrome P450, family 2, subfamily c, polypeptide 70
 33630
 0.13
chr10_52420605_52420773 1.07 Nus1
 NUS1 dehydrodolichyl diphosphate synthase subunit
 3142
 0.15
chr16_72808282_72808697 1.02 Robo1
 roundabout guidance receptor 1
 145285
 0.05
chr15_6218493_6218848 0.97 Gm23139
 predicted gene, 23139
 67322
 0.11
chr10_42723053_42723245 0.96 Gm15200
 predicted gene 15200
 24631
 0.14
chr17_50378350_50378501 0.94 Gm49906
 predicted gene, 49906
 39173
 0.17
chr17_24209788_24209956 0.94 Ntn3
 netrin 3
 341
 0.67
chr6_144070883_144071211 0.92 Sox5os1
 SRY (sex determining region Y)-box 5, opposite strand 1
 49139
 0.17
chr5_102010547_102010959 0.91 Wdfy3
 WD repeat and FYVE domain containing 3
 29195
 0.16
chr3_60034453_60034756 0.89 Aadac
 arylacetamide deacetylase
 2728
 0.23
chr4_4131153_4131310 0.86 A830012C17Rik
 RIKEN cDNA A830012C17 gene
 7090
 0.2
chr14_122602774_122602990 0.85 Pcca
 propionyl-Coenzyme A carboxylase, alpha polypeptide
 37
 0.98
chr7_132967481_132967632 0.84 Zranb1
 zinc finger, RAN-binding domain containing 1
 13303
 0.14
chr9_116136291_116136469 0.81 Tgfbr2
 transforming growth factor, beta receptor II
 38885
 0.15
chr15_42296635_42296795 0.78 Gm49452
 predicted gene, 49452
 23631
 0.17
chr8_48663447_48663609 0.76 Tenm3
 teneurin transmembrane protein 3
 11156
 0.25
chr9_83726172_83726335 0.75 Gm2109
 predicted gene 2109
 34778
 0.15
chr4_53099364_53099515 0.75 Abca1
 ATP-binding cassette, sub-family A (ABC1), member 1
 58513
 0.11
chr13_63113927_63114104 0.74 Aopep
 aminopeptidase O
 6493
 0.16
chr1_67168769_67168980 0.73 Cps1
 carbamoyl-phosphate synthetase 1
 45848
 0.15
chr1_13374931_13375133 0.70 Ncoa2
 nuclear receptor coactivator 2
 949
 0.34
chr17_43276058_43276209 0.68 Adgrf1
 adhesion G protein-coupled receptor F1
 5804
 0.29
chr6_149149841_149149992 0.68 Etfbkmt
 electron transfer flavoprotein beta subunit lysine methyltransferase
 8270
 0.13
chr13_21236545_21236716 0.67 Trim27
 tripartite motif-containing 27
 46769
 0.08
chr2_58782122_58782273 0.66 Upp2
 uridine phosphorylase 2
 16872
 0.2
chr2_72752692_72753055 0.65 6430710C18Rik
 RIKEN cDNA 6430710C18 gene
 2020
 0.38
chr9_106235817_106235968 0.65 Alas1
 aminolevulinic acid synthase 1
 1192
 0.3
chr3_77832077_77832234 0.64 Gm37576
 predicted gene, 37576
 40998
 0.19
chr5_147320087_147320238 0.63 Urad
 ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5) decarboxylase
 2278
 0.17
chr9_107305345_107305527 0.63 Gm17041
 predicted gene 17041
 3598
 0.12
chr15_53146756_53146975 0.62 Ext1
 exostosin glycosyltransferase 1
 38997
 0.23
chr18_66001524_66001695 0.62 Lman1
 lectin, mannose-binding, 1
 1009
 0.44
chr13_114974629_114975014 0.62 Gm47776
 predicted gene, 47776
 39753
 0.15
chr8_76152735_76152886 0.61 Gm45742
 predicted gene 45742
 35783
 0.19
chr4_61807807_61807958 0.61 Mup-ps16
 major urinary protein, pseudogene 16
 10400
 0.12
chr13_19395072_19395660 0.60 Gm42683
 predicted gene 42683
 87
 0.82
chr1_45922232_45922396 0.58 Slc40a1
 solute carrier family 40 (iron-regulated transporter), member 1
 995
 0.45
chr11_118201294_118201477 0.58 Gm11737
 predicted gene 11737
 3794
 0.18
chr8_69396075_69396226 0.58 Gm10033
 predicted gene 10033
 611
 0.64
chr1_67192772_67192960 0.58 Gm15668
 predicted gene 15668
 56334
 0.12
chr8_22893059_22893230 0.58 Gm45555
 predicted gene 45555
 19555
 0.14
chrX_101952539_101952717 0.57 Nhsl2
 NHS-like 2
 9169
 0.17
chr1_67213641_67214357 0.57 Gm15668
 predicted gene 15668
 35201
 0.17
chr3_52011351_52011543 0.57 Gm37465
 predicted gene, 37465
 7422
 0.13
chr2_144550194_144550414 0.56 Rbbp9
 retinoblastoma binding protein 9, serine hydrolase
 486
 0.71
chr19_36781247_36781436 0.56 Gm50112
 predicted gene, 50112
 37307
 0.14
chr2_160797467_160797706 0.56 Plcg1
 phospholipase C, gamma 1
 37468
 0.11
chr6_138156558_138156709 0.55 Mgst1
 microsomal glutathione S-transferase 1
 13779
 0.27
chr9_74791015_74791321 0.55 Gm22315
 predicted gene, 22315
 9098
 0.19
chr10_40511211_40511581 0.55 Gm18671
 predicted gene, 18671
 37496
 0.14
chr14_59443633_59443793 0.55 Cab39l
 calcium binding protein 39-like
 2732
 0.21
chr6_26490665_26490857 0.52 Gm24691
 predicted gene, 24691
 30331
 0.26
chr10_86690190_86690443 0.52 Gm15344
 predicted gene 15344
 2779
 0.1
chr10_107325957_107326150 0.51 Lin7a
 lin-7 homolog A (C. elegans)
 53659
 0.14
chr11_79884650_79884847 0.51 Gm24454
 predicted gene, 24454
 8967
 0.14
chr8_93073771_93073922 0.51 Ces1b
 carboxylesterase 1B
 6171
 0.16
chr18_9732141_9732318 0.51 Gm17430
 predicted gene, 17430
 5559
 0.13
chr18_59092890_59093288 0.51 Minar2
 membrane integral NOTCH2 associated receptor 2
 30578
 0.22
chr18_12760468_12760619 0.50 Osbpl1a
 oxysterol binding protein-like 1A
 6594
 0.15
chr14_62921769_62921931 0.50 Gm21021
 predicted gene, 21021
 51940
 0.08
chr2_73278335_73278505 0.50 Sp9
 trans-acting transcription factor 9
 6454
 0.16
chr6_119681087_119681251 0.50 Erc1
 ELKS/RAB6-interacting/CAST family member 1
 59064
 0.13
chr2_84648708_84648914 0.50 Ctnnd1
 catenin (cadherin associated protein), delta 1
 274
 0.82
chr19_31896510_31896684 0.50 Gm19241
 predicted gene, 19241
 17047
 0.2
chr14_47295909_47296231 0.50 Mapk1ip1l
 mitogen-activated protein kinase 1 interacting protein 1-like
 2196
 0.13
chr2_126934579_126934730 0.50 Sppl2a
 signal peptide peptidase like 2A
 1419
 0.4
chr1_67153777_67153928 0.50 Cps1
 carbamoyl-phosphate synthetase 1
 30826
 0.19
chr14_11125061_11125216 0.49 Fhit
 fragile histidine triad gene
 41
 0.98
chr9_35060528_35060679 0.49 St3gal4
 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
 4809
 0.2
chr12_32936719_32936876 0.49 Gm47961
 predicted gene, 47961
 5065
 0.13
chr2_167841674_167841862 0.48 1200007C13Rik
 RIKEN cDNA 1200007C13 gene
 8122
 0.16
chr15_10177985_10178196 0.48 Prlr
 prolactin receptor
 309
 0.94
chr13_37831757_37832025 0.48 Rreb1
 ras responsive element binding protein 1
 4498
 0.22
chr15_36595891_36596298 0.48 Pabpc1
 poly(A) binding protein, cytoplasmic 1
 1332
 0.34
chr4_53222171_53222454 0.48 4930412L05Rik
 RIKEN cDNA 4930412L05 gene
 4455
 0.21
chr4_6268102_6268325 0.48 Gm11798
 predicted gene 11798
 7248
 0.2
chr10_121501382_121501572 0.47 Gm46204
 predicted gene, 46204
 3874
 0.13
chr10_85957276_85957442 0.47 Rtcb
 RNA 2',3'-cyclic phosphate and 5'-OH ligase
 464
 0.7
chr3_63962435_63962754 0.47 Gm26850
 predicted gene, 26850
 1039
 0.38
chr2_18435403_18435565 0.46 Dnajc1
 DnaJ heat shock protein family (Hsp40) member C1
 42654
 0.16
chr1_67207008_67207510 0.46 Gm15668
 predicted gene 15668
 41941
 0.15
chr11_16915471_16915622 0.46 Egfr
 epidermal growth factor receptor
 10361
 0.18
chr13_24889964_24890115 0.45 D130043K22Rik
 RIKEN cDNA D130043K22 gene
 3042
 0.18
chr1_67150788_67150939 0.45 Cps1
 carbamoyl-phosphate synthetase 1
 27837
 0.2
chr1_162878367_162878530 0.45 Fmo2
 flavin containing monooxygenase 2
 2283
 0.28
chr15_3470264_3470480 0.45 Ghr
 growth hormone receptor
 1272
 0.6
chr6_94083257_94083610 0.44 Magi1
 membrane associated guanylate kinase, WW and PDZ domain containing 1
 169743
 0.03
chr5_131533929_131534082 0.44 Auts2
 autism susceptibility candidate 2
 392
 0.86
chr10_68090841_68090992 0.44 Arid5b
 AT rich interactive domain 5B (MRF1-like)
 45710
 0.14
chr17_77735813_77735964 0.44 Gm4711
 predicted gene 4711
 48539
 0.17
chr16_24103845_24103996 0.43 Gm31583
 predicted gene, 31583
 13831
 0.17
chr16_77461400_77461565 0.43 Mir99ahg
 Mir99a and Mirlet7c-1 host gene (non-protein coding)
 4439
 0.14
chr3_138375535_138375764 0.43 Adh6-ps1
 alcohol dehydrogenase 6 (class V), pseudogene 1
 1459
 0.3
chr19_26778570_26778772 0.43 Smarca2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
 7075
 0.21
chr19_32509968_32510223 0.42 Minpp1
 multiple inositol polyphosphate histidine phosphatase 1
 24172
 0.13
chr3_24595827_24596029 0.42 Gm24704
 predicted gene, 24704
 33854
 0.24
chr2_138258025_138258203 0.42 Btbd3
 BTB (POZ) domain containing 3
 1444
 0.6
chr15_38115472_38115623 0.42 Gm49312
 predicted gene, 49312
 36445
 0.12
chr7_114788616_114788767 0.41 Insc
 INSC spindle orientation adaptor protein
 3362
 0.24
chr18_76254862_76255034 0.40 Smad2
 SMAD family member 2
 6173
 0.2
chr8_105811176_105811604 0.40 Ranbp10
 RAN binding protein 10
 15815
 0.09
chr18_69659921_69660072 0.40 Tcf4
 transcription factor 4
 3329
 0.36
chr17_24861821_24861975 0.40 Hagh
 hydroxyacyl glutathione hydrolase
 3697
 0.1
chr15_36592351_36592502 0.39 Pabpc1
 poly(A) binding protein, cytoplasmic 1
 5000
 0.15
chr17_88304125_88304285 0.39 1700116H05Rik
 RIKEN cDNA 1700116H05 gene
 1173
 0.51
chr9_29643377_29643540 0.39 Gm15521
 predicted gene 15521
 50948
 0.19
chr2_152733626_152733777 0.39 Id1
 inhibitor of DNA binding 1, HLH protein
 2550
 0.16
chr14_17728323_17728474 0.38 Gm48320
 predicted gene, 48320
 42724
 0.19
chr9_55324808_55324982 0.38 Nrg4
 neuregulin 4
 292
 0.88
chr15_59430473_59430639 0.38 Nsmce2
 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
 56269
 0.12
chr14_21181534_21181685 0.38 Adk
 adenosine kinase
 105457
 0.06
chr3_116204045_116204241 0.38 Gm31651
 predicted gene, 31651
 3735
 0.2
chr3_138455131_138455312 0.38 Adh5
 alcohol dehydrogenase 5 (class III), chi polypeptide
 816
 0.51
chr17_84480594_84480759 0.37 Thada
 thyroid adenoma associated
 14471
 0.18
chr9_57525829_57526000 0.37 Cox5a
 cytochrome c oxidase subunit 5A
 4581
 0.1
chr9_70271019_70271199 0.37 Myo1e
 myosin IE
 63741
 0.11
chr15_96686781_96687182 0.37 Slc38a2
 solute carrier family 38, member 2
 11710
 0.16
chr4_131890254_131890430 0.37 Srsf4
 serine and arginine-rich splicing factor 4
 5134
 0.11
chr11_50312756_50312907 0.36 Canx
 calnexin
 11841
 0.12
chr11_19830960_19831117 0.36 Gm12029
 predicted gene 12029
 47386
 0.15
chr6_124709647_124709812 0.36 Emg1
 EMG1 N1-specific pseudouridine methyltransferase
 1316
 0.16
chr3_129606663_129606955 0.35 Elovl6
 ELOVL family member 6, elongation of long chain fatty acids (yeast)
 54429
 0.09
chr6_51720618_51721036 0.35 Gm38811
 predicted gene, 38811
 9746
 0.26
chr1_162571667_162571910 0.35 Vamp4
 vesicle-associated membrane protein 4
 562
 0.74
chr17_46026823_46026974 0.35 Vegfa
 vascular endothelial growth factor A
 2017
 0.29
chr4_3318885_3319036 0.35 Gm11786
 predicted gene 11786
 8215
 0.21
chr11_75754732_75754970 0.35 Ywhae
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
 3247
 0.21
chr6_100848852_100849036 0.34 Ppp4r2
 protein phosphatase 4, regulatory subunit 2
 3541
 0.26
chr19_56519861_56520029 0.34 Dclre1a
 DNA cross-link repair 1A
 17437
 0.17
chr7_46719930_46720314 0.34 Saa3
 serum amyloid A 3
 4422
 0.1
chr6_149147053_149147326 0.34 Etfbkmt
 electron transfer flavoprotein beta subunit lysine methyltransferase
 5543
 0.14
chr13_24144521_24144672 0.34 Carmil1
 capping protein regulator and myosin 1 linker 1
 10613
 0.19
chr10_87582564_87582726 0.33 Pah
 phenylalanine hydroxylase
 35972
 0.17
chr8_36319827_36320137 0.33 Gm5787
 predicted gene 5787
 53651
 0.12
chr1_13646788_13647045 0.33 Gm38319
 predicted gene, 38319
 4168
 0.2
chr5_103799401_103799738 0.33 Aff1
 AF4/FMR2 family, member 1
 15210
 0.19
chr2_59159714_59159865 0.33 Ccdc148
 coiled-coil domain containing 148
 745
 0.51
chr8_60947880_60948031 0.33 Clcn3
 chloride channel, voltage-sensitive 3
 6793
 0.17
chr16_91829363_91829514 0.33 Itsn1
 intersectin 1 (SH3 domain protein 1A)
 1901
 0.33
chr13_96795211_96795384 0.33 Ankrd31
 ankyrin repeat domain 31
 8701
 0.18
chr8_47708640_47708855 0.33 E030037K01Rik
 RIKEN cDNA E030037K01 gene
 4519
 0.12
chr13_43548363_43548529 0.33 Mcur1
 mitochondrial calcium uniporter regulator 1
 2326
 0.24
chr9_92251108_92251259 0.32 Plscr1
 phospholipid scramblase 1
 841
 0.56
chr11_83721035_83721187 0.32 Wfdc18
 WAP four-disulfide core domain 18
 11986
 0.08
chrX_42198771_42199059 0.32 Stag2
 stromal antigen 2
 46735
 0.14
chr6_91582630_91582782 0.32 Gm45215
 predicted gene 45215
 12052
 0.14
chr3_96562255_96562584 0.32 Txnip
 thioredoxin interacting protein
 2365
 0.12
chr4_6274068_6274223 0.32 Cyp7a1
 cytochrome P450, family 7, subfamily a, polypeptide 1
 1486
 0.41
chr11_113138785_113138971 0.32 2610035D17Rik
 RIKEN cDNA 2610035D17 gene
 34199
 0.21
chr13_81323962_81324134 0.32 Adgrv1
 adhesion G protein-coupled receptor V1
 18788
 0.24
chr5_87377364_87377538 0.32 Gm21049
 predicted gene, 21049
 2469
 0.16
chr6_17252773_17253114 0.31 Cav2
 caveolin 2
 28242
 0.16
chr16_93354892_93355097 0.31 1810053B23Rik
 RIKEN cDNA 1810053B23 gene
 892
 0.57
chr2_4929917_4930068 0.31 Phyh
 phytanoyl-CoA hydroxylase
 7491
 0.13
chr5_107369592_107369801 0.31 Brdt
 bromodomain, testis-specific
 9859
 0.11
chr12_59382932_59383083 0.31 Gm48268
 predicted gene, 48268
 27398
 0.14
chr19_56652542_56652727 0.31 Gm32441
 predicted gene, 32441
 11977
 0.17
chr5_123185860_123186059 0.31 Hpd
 4-hydroxyphenylpyruvic acid dioxygenase
 3232
 0.12
chr5_45278745_45278901 0.31 Gm43303
 predicted gene 43303
 26894
 0.18
chr17_78269187_78269367 0.31 Crim1
 cysteine rich transmembrane BMP regulator 1 (chordin like)
 10906
 0.19
chr6_119681279_119681450 0.31 Erc1
 ELKS/RAB6-interacting/CAST family member 1
 59259
 0.13
chr18_76752705_76752870 0.31 Skor2
 SKI family transcriptional corepressor 2
 103618
 0.07
chr14_120355831_120355991 0.31 Mbnl2
 muscleblind like splicing factor 2
 23330
 0.21
chr1_156558196_156558347 0.31 Abl2
 v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
 515
 0.76
chr13_91756942_91757255 0.31 Gm27656
 predicted gene, 27656
 4992
 0.17
chr9_111124362_111124513 0.30 Lrrfip2
 leucine rich repeat (in FLII) interacting protein 2
 4762
 0.17
chr1_107939897_107940125 0.30 D830032E09Rik
 RIKEN cDNA D830032E09 gene
 3302
 0.23
chr2_58755277_58755512 0.30 Upp2
 uridine phosphorylase 2
 182
 0.95
chr15_97048203_97048354 0.30 Slc38a4
 solute carrier family 38, member 4
 1809
 0.47
chr4_105116678_105116829 0.30 Prkaa2
 protein kinase, AMP-activated, alpha 2 catalytic subunit
 6863
 0.27
chr15_66613033_66613221 0.30 Phf20l1
 PHD finger protein 20-like 1
 967
 0.61
chr5_89352355_89352713 0.30 Gc
 vitamin D binding protein
 83094
 0.1
chr3_14841128_14841305 0.30 Car3
 carbonic anhydrase 3
 22296
 0.15
chr6_120686819_120687199 0.30 Cecr2
 CECR2, histone acetyl-lysine reader
 20427
 0.18
chr7_73549643_73549987 0.29 1810026B05Rik
 RIKEN cDNA 1810026B05 gene
 2950
 0.15
chr2_52613475_52613626 0.29 Bloc1s2-ps
 biogenesis of lysosomal organelles complex-1, subunit 2, pseudogene
 6204
 0.24
chr8_68060407_68060639 0.29 Psd3
 pleckstrin and Sec7 domain containing 3
 1704
 0.46
chrX_14897302_14897453 0.29 Gm9435
 predicted gene 9435
 58597
 0.15
chr11_77516276_77516445 0.29 Abhd15
 abhydrolase domain containing 15
 376
 0.44
chr13_113767020_113767171 0.29 Gm47463
 predicted gene, 47463
 2480
 0.19
chr19_8218872_8219037 0.29 Slc22a29
 solute carrier family 22. member 29
 54
 0.97
chr15_85766704_85766873 0.29 Ppara
 peroxisome proliferator activated receptor alpha
 5426
 0.16
chr10_19878984_19879150 0.29 Gm48714
 predicted gene, 48714
 4620
 0.19
chr2_27768705_27768856 0.28 Rxra
 retinoid X receptor alpha
 28579
 0.21
chr11_107473047_107473198 0.28 Pitpnc1
 phosphatidylinositol transfer protein, cytoplasmic 1
 2423
 0.19
chr9_110084221_110084372 0.27 Dhx30
 DEAH (Asp-Glu-Ala-His) box polypeptide 30
 695
 0.58
chr9_83576757_83576932 0.27 Sh3bgrl2
 SH3 domain binding glutamic acid-rich protein like 2
 13
 0.98
chr16_25967441_25967597 0.27 Gm4524
 predicted gene 4524
 11044
 0.22
chr12_35265470_35265829 0.27 Gm44396
 predicted gene, 44396
 43242
 0.16
chr7_73608284_73608633 0.27 Gm44734
 predicted gene 44734
 490
 0.68

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Cdc5l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.1 0.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.5 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.1 0.3 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.4 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.4 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.1 0.2 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.1 0.2 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.5 GO:0045908 negative regulation of vasodilation(GO:0045908)
0.1 0.2 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.2 GO:0015819 lysine transport(GO:0015819)
0.1 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.2 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.3 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.2 GO:0035627 ceramide transport(GO:0035627)
0.1 0.2 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.2 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.2 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0035523 protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.1 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.3 GO:0071397 cellular response to cholesterol(GO:0071397)
0.0 0.2 GO:1903367 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 0.3 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.0 GO:1900084 regulation of peptidyl-tyrosine autophosphorylation(GO:1900084)
0.0 0.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.2 GO:0046146 tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.1 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.0 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.0 GO:0014858 positive regulation of skeletal muscle cell proliferation(GO:0014858)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.6 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.0 0.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 0.1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.1 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
0.0 0.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.1 GO:0045794 negative regulation of cell volume(GO:0045794)
0.0 0.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:0090188 negative regulation of pancreatic juice secretion(GO:0090188)
0.0 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:1901970 positive regulation of mitotic sister chromatid separation(GO:1901970)
0.0 0.0 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.1 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0 0.1 GO:0015838 amino-acid betaine transport(GO:0015838)
0.0 0.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.0 0.0 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.0 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.0 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.0 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.0 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.0 GO:1903972 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.0 0.0 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0045176 apical protein localization(GO:0045176)
0.0 0.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:1900045 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.0 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.2 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.0 GO:0015817 histidine transport(GO:0015817)
0.0 0.0 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0030836 positive regulation of actin filament depolymerization(GO:0030836)
0.0 0.0 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.0 0.0 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.0 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.2 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.1 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.0 GO:0070375 ERK5 cascade(GO:0070375)
0.0 0.0 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.0 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:0051457 maintenance of protein location in nucleus(GO:0051457)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.4 GO:0005915 zonula adherens(GO:0005915)
0.1 0.2 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0045293 mRNA editing complex(GO:0045293)
0.0 0.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.3 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 0.0 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0034364 high-density lipoprotein particle(GO:0034364)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0004075 biotin carboxylase activity(GO:0004075)
0.1 0.6 GO:0016151 nickel cation binding(GO:0016151)
0.1 0.3 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 0.2 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0015189 arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.6 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.3 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.0 0.1 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0 0.5 GO:0052770 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.0 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.6 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.0 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.0 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.0 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.4 GO:0052767 prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.0 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0 0.0 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics