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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Clock

Z-value: 0.95

Motif logo

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Transcription factors associated with Clock

Gene Symbol Gene ID Gene Info
Clock
ENSMUSG00000029238.8 circadian locomotor output cycles kaput

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr5_76304107_76304258Clock3660.632461-0.872.3e-02Click!
chr5_76303540_76303814Clock8710.362384-0.796.4e-02Click!
chr5_76303922_76304075Clock5500.511694-0.758.5e-02Click!
chr5_76304752_76304909Clock380.497417-0.612.0e-01Click!
chr5_76256521_76256672Clock174160.1235110.443.8e-01Click!

Activity of the Clock motif across conditions

Conditions sorted by the z-value of the Clock motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr4_124005727_124005878 1.93 Gm12902
 predicted gene 12902
 79568
 0.07
chr16_48765285_48765461 1.64 Trat1
 T cell receptor associated transmembrane adaptor 1
 6583
 0.2
chr9_74331308_74331508 1.27 Gm24141
 predicted gene, 24141
 31202
 0.18
chr11_118265609_118265912 0.98 Usp36
 ubiquitin specific peptidase 36
 288
 0.89
chr19_33489637_33489788 0.89 Lipo5
 lipase, member O5
 16521
 0.14
chr19_33480626_33480777 0.88 Lipo5
 lipase, member O5
 7510
 0.16
chr1_186358132_186358570 0.82 Gm37491
 predicted gene, 37491
 11036
 0.28
chr17_71616884_71617050 0.78 Wdr43
 WD repeat domain 43
 752
 0.37
chr14_20479878_20480231 0.75 Anxa7
 annexin A7
 67
 0.96
chr4_101176228_101176401 0.75 Jak1
 Janus kinase 1
 9111
 0.15
chr5_8157542_8157699 0.68 Gm21759
 predicted gene, 21759
 22016
 0.16
chr10_95152509_95152710 0.58 Gm29684
 predicted gene, 29684
 6784
 0.16
chr6_148833285_148833458 0.58 Ipo8
 importin 8
 1904
 0.22
chr5_54060085_54060253 0.58 Stim2
 stromal interaction molecule 2
 14568
 0.23
chr18_60922022_60922173 0.57 Camk2a
 calcium/calmodulin-dependent protein kinase II alpha
 3521
 0.17
chr3_57435352_57435577 0.56 Tm4sf4
 transmembrane 4 superfamily member 4
 10150
 0.22
chr7_68311256_68311435 0.47 4930405G09Rik
 RIKEN cDNA 4930405G09 gene
 5687
 0.14
chr18_38406873_38407073 0.44 Ndfip1
 Nedd4 family interacting protein 1
 3423
 0.18
chr3_96092507_96092658 0.43 Gm43554
 predicted gene 43554
 5711
 0.11
chr19_37433970_37434137 0.41 Gm38345
 predicted gene, 38345
 603
 0.45
chr10_89484240_89484407 0.41 Nr1h4
 nuclear receptor subfamily 1, group H, member 4
 22326
 0.19
chrX_52044793_52044944 0.39 1700080O16Rik
 RIKEN cDNA 1700080O16 gene
 72096
 0.11
chr3_65663297_65663473 0.39 Lekr1
 leucine, glutamate and lysine rich 1
 2843
 0.19
chr2_156065132_156065865 0.37 Spag4
 sperm associated antigen 4
 55
 0.94
chr11_61974443_61974594 0.37 Gm12274
 predicted gene 12274
 168
 0.92
chr14_21832226_21832384 0.37 Vdac2
 voltage-dependent anion channel 2
 142
 0.94
chr11_61092676_61092849 0.37 Kcnj12
 potassium inwardly-rectifying channel, subfamily J, member 12
 26958
 0.13
chr9_107674967_107675413 0.36 Gnat1
 guanine nucleotide binding protein, alpha transducing 1
 1251
 0.24
chr4_63268906_63269081 0.35 Mir455
 microRNA 455
 12142
 0.16
chr6_50526613_50527019 0.35 Gm26289
 predicted gene, 26289
 13218
 0.13
chr11_44518397_44518764 0.35 Rnf145
 ring finger protein 145
 384
 0.85
chr11_120811562_120811973 0.35 Fasn
 fatty acid synthase
 2066
 0.16
chr10_96778362_96778523 0.34 Gm6859
 predicted gene 6859
 8614
 0.17
chr6_28895214_28895400 0.34 Snd1
 staphylococcal nuclease and tudor domain containing 1
 15264
 0.21
chr18_51128419_51128586 0.34 Prr16
 proline rich 16
 10764
 0.3
chr7_144940237_144940434 0.33 Ccnd1
 cyclin D1
 410
 0.78
chr1_131716457_131716608 0.32 Rab7b
 RAB7B, member RAS oncogene family
 19894
 0.14
chr19_26764962_26765268 0.32 Smarca2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
 5376
 0.24
chr8_46216985_46217176 0.31 Slc25a4
 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
 5796
 0.11
chr2_134486534_134486685 0.31 Hao1
 hydroxyacid oxidase 1, liver
 67698
 0.14
chr5_87373500_87373711 0.31 Gm35570
 predicted gene, 35570
 3122
 0.14
chr14_69729450_69729663 0.31 Chmp7
 charged multivesicular body protein 7
 1319
 0.33
chr7_79363538_79363689 0.31 Rlbp1
 retinaldehyde binding protein 1
 14090
 0.13
chr11_5912275_5912428 0.30 Gck
 glucokinase
 2773
 0.16
chr6_117577945_117578096 0.29 Gm9946
 predicted gene 9946
 10348
 0.2
chr4_150218378_150218529 0.29 Gm13094
 predicted gene 13094
 9582
 0.13
chr13_63665698_63665976 0.29 Gm47387
 predicted gene, 47387
 4040
 0.18
chr19_40417273_40417445 0.29 Sorbs1
 sorbin and SH3 domain containing 1
 15092
 0.22
chr16_43552061_43552212 0.29 Zbtb20
 zinc finger and BTB domain containing 20
 41828
 0.16
chr11_82845122_82845302 0.28 Rffl
 ring finger and FYVE like domain containing protein
 880
 0.45
chr8_109681119_109681276 0.28 Ist1
 increased sodium tolerance 1 homolog (yeast)
 3603
 0.19
chr4_117981260_117981475 0.27 9530034E10Rik
 RIKEN cDNA 9530034E10 gene
 6331
 0.16
chr10_19443595_19443775 0.27 Gm33104
 predicted gene, 33104
 43030
 0.15
chr3_27283500_27283672 0.26 Gm37191
 predicted gene, 37191
 5526
 0.2
chr10_62647927_62648078 0.26 Ddx50
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
 221
 0.89
chr15_93628063_93628509 0.26 Prickle1
 prickle planar cell polarity protein 1
 32395
 0.18
chr1_88316757_88316908 0.25 Trpm8
 transient receptor potential cation channel, subfamily M, member 8
 2081
 0.23
chr4_150119850_150120001 0.25 Slc2a5
 solute carrier family 2 (facilitated glucose transporter), member 5
 642
 0.38
chr1_92834707_92834858 0.25 Gpc1
 glypican 1
 2813
 0.15
chr3_129589919_129590070 0.24 Elovl6
 ELOVL family member 6, elongation of long chain fatty acids (yeast)
 37614
 0.13
chr2_172511032_172511203 0.24 Gm14303
 predicted gene 14303
 1426
 0.37
chr2_94430791_94430942 0.24 Api5
 apoptosis inhibitor 5
 1122
 0.47
chr6_85919471_85919834 0.24 Gm18290
 predicted gene, 18290
 1766
 0.16
chr7_137068941_137069100 0.24 Gm45499
 predicted gene 45499
 98800
 0.07
chr16_87710092_87710297 0.24 Bach1
 BTB and CNC homology 1, basic leucine zipper transcription factor 1
 11190
 0.21
chr1_131619346_131619811 0.23 Gm8532
 predicted gene 8532
 13391
 0.14
chr3_19225975_19226148 0.23 Gm16093
 predicted gene 16093
 1719
 0.33
chr7_19675959_19676128 0.23 Apoc2
 apolipoprotein C-II
 821
 0.36
chr5_124236533_124236706 0.22 Gm42425
 predicted gene 42425
 1105
 0.35
chr8_45264437_45264634 0.22 F11
 coagulation factor XI
 2504
 0.25
chr1_128440773_128440930 0.22 Dars
 aspartyl-tRNA synthetase
 23483
 0.14
chr8_121967787_121967995 0.22 Gm17709
 predicted gene, 17709
 5931
 0.11
chr1_194361449_194361616 0.22 4930503O07Rik
 RIKEN cDNA 4930503O07 gene
 138773
 0.05
chr9_55277532_55277801 0.22 Nrg4
 neuregulin 4
 5906
 0.19
chr8_95360199_95360374 0.21 Mmp15
 matrix metallopeptidase 15
 8018
 0.13
chr10_21328387_21328563 0.21 4930455C13Rik
 RIKEN cDNA 4930455C13 gene
 13582
 0.14
chr11_49233858_49234036 0.21 Mgat1
 mannoside acetylglucosaminyltransferase 1
 10244
 0.12
chr7_16615699_16615891 0.21 Gm44589
 predicted gene 44589
 556
 0.43
chr6_88737581_88737810 0.21 Gm44005
 predicted gene, 44005
 497
 0.7
chr3_10174352_10174597 0.21 Pmp2
 peripheral myelin protein 2
 9455
 0.12
chr18_50139098_50139320 0.20 Hsd17b4
 hydroxysteroid (17-beta) dehydrogenase 4
 3160
 0.23
chr16_90282950_90283226 0.20 Scaf4
 SR-related CTD-associated factor 4
 1220
 0.43
chr18_44540279_44540430 0.20 Mcc
 mutated in colorectal cancers
 20838
 0.24
chr13_5714270_5714464 0.20 Gm35330
 predicted gene, 35330
 10075
 0.27
chr9_106235574_106235761 0.20 Alas1
 aminolevulinic acid synthase 1
 1417
 0.25
chr4_57250984_57251161 0.20 Ptpn3
 protein tyrosine phosphatase, non-receptor type 3
 29018
 0.17
chr1_13312454_13312771 0.20 Ncoa2
 nuclear receptor coactivator 2
 12890
 0.11
chr2_11513206_11513376 0.19 Gm10851
 predicted gene 10851
 8415
 0.14
chr8_126309380_126309531 0.19 Slc35f3
 solute carrier family 35, member F3
 10897
 0.27
chr6_91424316_91424467 0.19 Gm4575
 predicted gene 4575
 4492
 0.12
chr5_124424178_124424509 0.19 Gm37415
 predicted gene, 37415
 354
 0.67
chr5_45857473_45857990 0.19 4930449I04Rik
 RIKEN cDNA 4930449I04 gene
 89
 0.53
chr9_72260390_72260691 0.19 Gm25163
 predicted gene, 25163
 3401
 0.12
chr7_140767390_140767578 0.18 Cyp2e1
 cytochrome P450, family 2, subfamily e, polypeptide 1
 3003
 0.12
chr5_144370961_144371328 0.18 Dmrt1i
 Dmrt1 interacting ncRNA
 12619
 0.16
chr9_13681735_13681905 0.18 Maml2
 mastermind like transcriptional coactivator 2
 19360
 0.18
chr15_77928675_77928831 0.18 Txn2
 thioredoxin 2
 215
 0.92
chr2_30545170_30545343 0.18 Gm14487
 predicted gene 14487
 10527
 0.17
chr4_124682416_124682588 0.17 Utp11
 UTP11 small subunit processome component
 11032
 0.09
chr2_122075180_122075331 0.17 Spg11
 SPG11, spatacsin vesicle trafficking associated
 43041
 0.09
chr16_78371572_78371756 0.16 Btg3
 BTG anti-proliferation factor 3
 1672
 0.33
chr16_7144291_7144454 0.16 Rbfox1
 RNA binding protein, fox-1 homolog (C. elegans) 1
 49375
 0.2
chr2_119476960_119477373 0.16 Ino80
 INO80 complex subunit
 447
 0.8
chr7_24850067_24850266 0.16 Gm18207
 predicted gene, 18207
 10780
 0.08
chr3_97642273_97642480 0.16 Fmo5
 flavin containing monooxygenase 5
 13493
 0.12
chr6_17463758_17464495 0.16 Met
 met proto-oncogene
 19
 0.98
chr2_27675051_27675434 0.15 Rxra
 retinoid X receptor alpha
 1198
 0.58
chr4_136675586_136676002 0.15 Ephb2
 Eph receptor B2
 14142
 0.15
chr14_61125286_61125469 0.15 Sacs
 sacsin
 13080
 0.21
chr2_152360517_152360697 0.15 Gm14165
 predicted gene 14165
 6992
 0.09
chr1_153691155_153691333 0.15 Gm29529
 predicted gene 29529
 1412
 0.3
chr5_127615097_127615417 0.15 Slc15a4
 solute carrier family 15, member 4
 1626
 0.29
chr5_122239684_122239867 0.15 Tctn1
 tectonic family member 1
 11903
 0.12
chrX_7422915_7423070 0.15 2010204K13Rik
 RIKEN cDNA 2010204K13 gene
 4
 0.97
chr8_70395705_70396002 0.15 Crtc1
 CREB regulated transcription coactivator 1
 6945
 0.12
chr19_43813317_43813611 0.15 Abcc2
 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
 2942
 0.21
chr5_114951424_114951834 0.15 2210016L21Rik
 RIKEN cDNA 2210016L21 gene
 5824
 0.09
chr4_46868313_46868486 0.14 Gabbr2
 gamma-aminobutyric acid (GABA) B receptor, 2
 8497
 0.27
chr12_73353785_73353952 0.14 Gm48653
 predicted gene, 48653
 1213
 0.43
chr11_51859695_51859870 0.14 Jade2
 jade family PHD finger 2
 2129
 0.29
chr5_146967227_146967378 0.14 Mtif3
 mitochondrial translational initiation factor 3
 3502
 0.21
chr4_122977007_122977265 0.14 4933421A08Rik
 RIKEN cDNA 4933421A08 gene
 15827
 0.12
chr15_55122695_55122962 0.14 Gm9920
 predicted gene 9920
 9151
 0.15
chrX_60008756_60008925 0.14 F9
 coagulation factor IX
 9376
 0.21
chr4_123960615_123960766 0.14 Gm12902
 predicted gene 12902
 34456
 0.11
chr19_32524150_32524376 0.14 Gm36419
 predicted gene, 36419
 19085
 0.15
chr8_71700006_71700195 0.14 B3gnt3
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
 1689
 0.18
chr9_106447373_106447582 0.14 Abhd14b
 abhydrolase domain containing 14b
 18
 0.49
chr3_138256816_138256967 0.14 Adh1
 alcohol dehydrogenase 1 (class I)
 4100
 0.14
chr5_39219850_39220015 0.13 Gm40293
 predicted gene, 40293
 87152
 0.08
chr7_141064386_141064940 0.13 B4galnt4
 beta-1,4-N-acetyl-galactosaminyl transferase 4
 169
 0.88
chr5_100430036_100430187 0.13 Gm42690
 predicted gene 42690
 385
 0.59
chrX_38423271_38423435 0.13 Lamp2
 lysosomal-associated membrane protein 2
 19797
 0.15
chr12_54405210_54405378 0.13 Gm46328
 predicted gene, 46328
 5118
 0.16
chr5_20704249_20704400 0.13 Magi2
 membrane associated guanylate kinase, WW and PDZ domain containing 2
 2655
 0.3
chr19_57368390_57368551 0.13 Fam160b1
 family with sequence similarity 160, member B1
 7440
 0.16
chr15_7154102_7154264 0.13 Lifr
 LIF receptor alpha
 170
 0.97
chr15_39111986_39112168 0.12 Slc25a32
 solute carrier family 25, member 32
 555
 0.51
chr11_116483917_116484077 0.12 Prpsap1
 phosphoribosyl pyrophosphate synthetase-associated protein 1
 5677
 0.11
chr5_64114340_64114507 0.12 Pgm2
 phosphoglucomutase 2
 2322
 0.2
chr1_153697619_153697798 0.12 Gm29529
 predicted gene 29529
 5052
 0.13
chr10_42524541_42524692 0.12 Snx3
 sorting nexin 3
 22326
 0.16
chr2_91242516_91242810 0.12 Ddb2
 damage specific DNA binding protein 2
 5681
 0.11
chr18_68062225_68062529 0.12 Gm41764
 predicted gene, 41764
 55997
 0.13
chr11_65131461_65131612 0.12 1700086D15Rik
 RIKEN cDNA 1700086D15 gene
 28354
 0.12
chr10_44321957_44322108 0.12 Mir1929
 microRNA 1929
 37644
 0.15
chr15_76594336_76594507 0.12 Adck5
 aarF domain containing kinase 5
 128
 0.89
chr1_167746804_167746963 0.12 Lmx1a
 LIM homeobox transcription factor 1 alpha
 57326
 0.15
chr8_70372073_70372256 0.11 Comp
 cartilage oligomeric matrix protein
 1394
 0.28
chr11_120491297_120491754 0.11 Slc25a10
 solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
 315
 0.64
chr2_120348240_120348405 0.11 Vps39
 VPS39 HOPS complex subunit
 4115
 0.19
chr18_75502781_75502947 0.11 Gm10532
 predicted gene 10532
 11781
 0.26
chr12_105000981_105001188 0.11 Syne3
 spectrin repeat containing, nuclear envelope family member 3
 2407
 0.18
chr5_123023127_123023430 0.11 Orai1
 ORAI calcium release-activated calcium modulator 1
 7940
 0.09
chr6_114918998_114919299 0.11 Vgll4
 vestigial like family member 4
 2668
 0.32
chr6_100636259_100636566 0.11 Gm44108
 predicted gene, 44108
 9472
 0.15
chr8_3277578_3277729 0.11 Insr
 insulin receptor
 1898
 0.34
chr2_18543019_18543179 0.11 Gm13353
 predicted gene 13353
 25027
 0.2
chr13_80894659_80894898 0.11 Arrdc3
 arrestin domain containing 3
 4260
 0.19
chr16_33966526_33966697 0.11 Gm15829
 predicted gene 15829
 372
 0.48
chr4_59438657_59438836 0.11 Susd1
 sushi domain containing 1
 113
 0.97
chr16_52129443_52129606 0.11 Cblb
 Casitas B-lineage lymphoma b
 23002
 0.21
chr11_99105971_99106266 0.10 Tns4
 tensin 4
 16812
 0.14
chr11_101569721_101569872 0.10 Nbr1
 NBR1, autophagy cargo receptor
 1109
 0.3
chr1_88411027_88411203 0.10 Spp2
 secreted phosphoprotein 2
 3709
 0.2
chr4_6908644_6908795 0.10 Tox
 thymocyte selection-associated high mobility group box
 81764
 0.11
chr1_168357153_168357454 0.10 Gm38381
 predicted gene, 38381
 6495
 0.24
chr1_170815209_170815368 0.10 Gm25235
 predicted gene, 25235
 17583
 0.12
chr17_34898174_34898489 0.10 C2
 complement component 2 (within H-2S)
 66
 0.57
chr7_114461865_114462041 0.10 Pde3b
 phosphodiesterase 3B, cGMP-inhibited
 44225
 0.15
chr8_62184095_62184246 0.10 Gm2961
 predicted gene 2961
 10042
 0.27
chr5_111509539_111510088 0.10 C130026L21Rik
 RIKEN cDNA C130026L21 gene
 71609
 0.09
chr12_31950204_31950930 0.10 Hbp1
 high mobility group box transcription factor 1
 32
 0.98
chr1_52499794_52500020 0.10 Nab1
 Ngfi-A binding protein 1
 393
 0.8
chr6_99145207_99145385 0.10 Foxp1
 forkhead box P1
 17722
 0.26
chr7_81588668_81588888 0.10 Gm45698
 predicted gene 45698
 2116
 0.19
chr2_35211769_35211922 0.09 Rab14
 RAB14, member RAS oncogene family
 10725
 0.14
chr6_95163817_95164232 0.09 Kbtbd8
 kelch repeat and BTB (POZ) domain containing 8
 46040
 0.12
chr3_35892773_35892978 0.09 Dcun1d1
 DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)
 16970
 0.12
chr8_120046377_120046540 0.09 Gm15684
 predicted gene 15684
 1171
 0.4
chr8_13055180_13055331 0.09 Proz
 protein Z, vitamin K-dependent plasma glycoprotein
 5659
 0.1
chr6_116015696_116015857 0.09 Plxnd1
 plexin D1
 20771
 0.14
chr6_108662142_108662337 0.09 Bhlhe40
 basic helix-loop-helix family, member e40
 807
 0.49
chr4_141452237_141452709 0.09 Zbtb17
 zinc finger and BTB domain containing 17
 7767
 0.11
chr11_101700898_101701098 0.09 Dhx8
 DEAH (Asp-Glu-Ala-His) box polypeptide 8
 31921
 0.08
chr2_3424682_3424836 0.09 Dclre1c
 DNA cross-link repair 1C
 557
 0.63
chr18_61373998_61374172 0.08 Gm25301
 predicted gene, 25301
 23728
 0.12
chr7_49351868_49352264 0.08 Gm44913
 predicted gene 44913
 5972
 0.24
chr11_55468108_55468290 0.08 G3bp1
 GTPase activating protein (SH3 domain) binding protein 1
 1486
 0.25
chr11_82852598_82853205 0.08 Rffl
 ring finger and FYVE like domain containing protein
 6809
 0.12
chr2_48442189_48442365 0.08 Gm13481
 predicted gene 13481
 14968
 0.23
chr9_54844002_54844168 0.08 Rab7-ps1
 RAB7, member RAS oncogene family, pseudogene 1
 18803
 0.15
chr8_40907855_40908028 0.08 Slc7a2
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
 9503
 0.16
chr3_32399514_32399821 0.08 Pik3ca
 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
 1996
 0.29
chr9_18293076_18293227 0.08 Chordc1
 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
 763
 0.59
chr19_40471969_40472156 0.08 Sorbs1
 sorbin and SH3 domain containing 1
 15493
 0.2
chr6_144311505_144311701 0.08 Sox5
 SRY (sex determining region Y)-box 5
 102035
 0.08
chr2_101831932_101832083 0.08 Prr5l
 proline rich 5 like
 6973
 0.23
chr11_88181207_88181562 0.08 Cuedc1
 CUE domain containing 1
 919
 0.56
chr18_33780213_33780407 0.08 Epb41l4aos
 erythrocyte membrane protein band 4.1 like 4a, opposite strand
 14582
 0.18

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Clock

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.3 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 0.3 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 0.7 GO:0009992 cellular water homeostasis(GO:0009992)
0.0 0.4 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0061010 gall bladder development(GO:0061010)
0.0 0.1 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.1 GO:0015755 fructose transport(GO:0015755)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.0 0.1 GO:0010915 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 0.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.8 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.1 GO:0015817 histidine transport(GO:0015817)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0015888 thiamine transport(GO:0015888)
0.0 0.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.1 GO:0046049 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.0 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.0 GO:0036166 phenotypic switching(GO:0036166)
0.0 0.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.1 GO:0042414 epinephrine metabolic process(GO:0042414)
0.0 0.0 GO:0015744 succinate transport(GO:0015744)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.0 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.0 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.0 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.0 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.0 GO:0030167 proteoglycan catabolic process(GO:0030167)
0.0 0.0 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:0051031 tRNA transport(GO:0051031)
0.0 0.1 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.0 GO:0009838 abscission(GO:0009838)
0.0 0.0 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.0 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.1 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.0 GO:0048254 snoRNA localization(GO:0048254)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.0 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.0 GO:0097441 basilar dendrite(GO:0097441)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0070061 fructose binding(GO:0070061)
0.0 0.1 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.0 0.0 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.0 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.0 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.0 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.0 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0034902 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 0.0 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.0 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.0 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling