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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Creb1

Z-value: 2.94

Motif logo

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Transcription factors associated with Creb1

Gene Symbol Gene ID Gene Info
Creb1
ENSMUSG00000025958.8 cAMP responsive element binding protein 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr1_64532638_64532840Creb1580.9791070.796.1e-02Click!
chr1_64532373_64532537Creb11900.9542260.749.1e-02Click!
chr1_64533839_64534218Creb111340.542687-0.522.9e-01Click!
chr1_64544062_64544226Creb1112500.2046640.513.1e-01Click!
chr1_64533549_64533792Creb17760.6868970.443.9e-01Click!

Activity of the Creb1 motif across conditions

Conditions sorted by the z-value of the Creb1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr18_67610813_67610964 1.45 Spire1
 spire type actin nucleation factor 1
 98
 0.96
chr4_130275585_130275744 1.33 Serinc2
 serine incorporator 2
 78
 0.97
chr14_18238484_18238667 1.00 Nr1d2
 nuclear receptor subfamily 1, group D, member 2
 436
 0.77
chr4_119294177_119294328 0.85 Ybx1
 Y box protein 1
 228
 0.82
chr9_96119153_96119334 0.82 Gk5
 glycerol kinase 5 (putative)
 119
 0.97
chr2_168731544_168731695 0.76 Atp9a
 ATPase, class II, type 9A
 2720
 0.27
chr17_34031956_34032112 0.76 Rxrb
 retinoid X receptor beta
 162
 0.56
chr5_110652988_110653519 0.74 Noc4l
 NOC4 like
 6
 0.71
chr5_112342985_112343154 0.73 Hps4
 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2
 14
 0.5
chr9_121995692_121995846 0.70 Pomgnt2
 protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2
 236
 0.59
chr12_87200154_87200311 0.68 Tmed8
 transmembrane p24 trafficking protein 8
 222
 0.58
chr13_113035052_113035231 0.68 Cdc20b
 cell division cycle 20B
 30
 0.91
chr13_73603860_73604045 0.68 Clptm1l
 CLPTM1-like
 54
 0.97
chr1_153154371_153154533 0.66 Lamc2
 laminin, gamma 2
 2366
 0.31
chr11_96034634_96034968 0.64 Snf8
 SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
 84
 0.93
chr12_70111679_70111850 0.64 Nin
 ninein
 135
 0.94
chr4_108780712_108780909 0.64 Zfyve9
 zinc finger, FYVE domain containing 9
 12
 0.97
chr6_124712105_124712263 0.61 Emg1
 EMG1 N1-specific pseudouridine methyltransferase
 6
 0.63
chr3_19311274_19311435 0.60 Pde7a
 phosphodiesterase 7A
 32
 0.98
chr5_44226591_44226765 0.59 Tapt1
 transmembrane anterior posterior transformation 1
 52
 0.54
chr9_123113166_123113328 0.59 Exosc7
 exosome component 7
 0
 0.51
chr10_44268265_44268427 0.58 Atg5
 autophagy related 5
 12
 0.98
chr19_61226557_61226761 0.57 Csf2ra
 colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
 24
 0.96
chr1_185362884_185363044 0.56 Eprs
 glutamyl-prolyl-tRNA synthetase
 80
 0.51
chr10_94688514_94688673 0.55 Cep83os
 centrosomal protein 83, opposite strand
 17
 0.53
chr17_35979910_35980068 0.55 Gnl1
 guanine nucleotide binding protein-like 1
 138
 0.53
chr11_59948102_59948262 0.55 Med9
 mediator complex subunit 9
 24
 0.5
chr13_38635056_38635216 0.54 Bloc1s5
 biogenesis of lysosomal organelles complex-1, subunit 5, muted
 27
 0.67
chr11_69008415_69008579 0.53 Pfas
 phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)
 37
 0.94
chr1_134361941_134362097 0.52 Tmem183a
 transmembrane protein 183A
 40
 0.96
chr12_4907675_4907836 0.51 Ubxn2a
 UBX domain protein 2A
 50
 0.97
chr7_60622702_60622860 0.50 Gm3198
 predicted gene 3198
 21110
 0.24
chr18_31910656_31910818 0.50 Sft2d3
 SFT2 domain containing 3
 1087
 0.41
chr18_36280963_36281137 0.50 Pura
 purine rich element binding protein A
 47
 0.98
chr11_93995780_93995964 0.49 Spag9
 sperm associated antigen 9
 219
 0.92
chr7_67951713_67951868 0.48 Igf1r
 insulin-like growth factor I receptor
 1037
 0.59
chr9_113741327_113741516 0.48 Clasp2
 CLIP associating protein 2
 52
 0.98
chr16_18248879_18249038 0.48 Trmt2a
 TRM2 tRNA methyltransferase 2A
 44
 0.71
chr5_30869500_30869676 0.47 Tmem214
 transmembrane protein 214
 43
 0.93
chr16_76372938_76373097 0.46 Nrip1
 nuclear receptor interacting protein 1
 20
 0.98
chr9_103092268_103092439 0.46 Gm47468
 predicted gene, 47468
 6816
 0.16
chr13_46727890_46728179 0.46 Nup153
 nucleoporin 153
 94
 0.97
chr2_112454883_112455043 0.46 Emc7
 ER membrane protein complex subunit 7
 34
 0.97
chr12_3235659_3235825 0.44 Rab10os
 RAB10, member RAS oncogene family, opposite strand
 49
 0.97
chr16_4419831_4420028 0.44 Adcy9
 adenylate cyclase 9
 121
 0.97
chr17_28280441_28280673 0.43 Ppard
 peroxisome proliferator activator receptor delta
 8438
 0.11
chr8_94696147_94696319 0.43 Pllp
 plasma membrane proteolipid
 45
 0.96
chr7_60244322_60244473 0.43 Gm18129
 predicted gene, 18129
 28463
 0.13
chr5_98167616_98167767 0.42 Prdm8
 PR domain containing 8
 493
 0.78
chr5_135064073_135064243 0.42 Dnajc30
 DnaJ heat shock protein family (Hsp40) member C30
 44
 0.51
chr5_124032266_124032428 0.42 Gm34086
 predicted gene, 34086
 14
 0.54
chr17_71598722_71598884 0.42 Trmt61b
 tRNA methyltransferase 61B
 48
 0.95
chr10_62920435_62920743 0.41 Slc25a16
 solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
 44
 0.95
chr4_131843361_131843528 0.41 Mecr
 mitochondrial trans-2-enoyl-CoA reductase
 26
 0.96
chr12_71016661_71016812 0.41 Arid4a
 AT rich interactive domain 4A (RBP1-like)
 28
 0.95
chr4_117737643_117737808 0.41 Gm12844
 predicted gene 12844
 8426
 0.13
chr12_73286678_73286838 0.41 Slc38a6
 solute carrier family 38, member 6
 21
 0.51
chr9_104574587_104574746 0.41 Cpne4
 copine IV
 4879
 0.3
chr8_60983261_60983420 0.41 Clcn3
 chloride channel, voltage-sensitive 3
 40
 0.56
chr5_140777102_140777260 0.40 Amz1
 archaelysin family metallopeptidase 1
 27898
 0.16
chr10_30200517_30200678 0.40 Cenpw
 centromere protein W
 37
 0.98
chr8_109737758_109738093 0.40 Atxn1l
 ataxin 1-like
 186
 0.93
chr7_127708585_127708750 0.40 Bcl7c
 B cell CLL/lymphoma 7C
 28
 0.67
chr13_21735165_21735383 0.39 H4c11
 H4 clustered histone 11
 210
 0.76
chr5_3543702_3543859 0.39 Fam133b
 family with sequence similarity 133, member B
 53
 0.75
chr1_165772571_165772722 0.39 Creg1
 cellular repressor of E1A-stimulated genes 1
 3170
 0.12
chr2_181287544_181287702 0.39 Gmeb2
 glucocorticoid modulatory element binding protein 2
 393
 0.73
chr4_131825946_131826107 0.38 Ptpru
 protein tyrosine phosphatase, receptor type, U
 4510
 0.17
chr2_144270828_144271000 0.38 Snx5
 sorting nexin 5
 8
 0.49
chr5_24164869_24165024 0.38 Nupl2
 nucleoporin like 2
 17
 0.97
chr17_47360088_47360253 0.38 Mrps10
 mitochondrial ribosomal protein S10
 8717
 0.13
chr2_28908586_28908768 0.38 Barhl1
 BarH like homeobox 1
 3818
 0.2
chr2_33887473_33887624 0.38 Mvb12b
 multivesicular body subunit 12B
 66
 0.98
chr5_139668626_139668800 0.38 Gm42424
 predicted gene 42424
 32934
 0.14
chr8_111027673_111027836 0.38 Ddx19b
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b
 10
 0.95
chr5_35582848_35583008 0.38 Acox3
 acyl-Coenzyme A oxidase 3, pristanoyl
 112
 0.95
chr3_116333321_116333755 0.37 Gm29151
 predicted gene 29151
 16565
 0.18
chr4_108619791_108619963 0.37 Gm12743
 predicted gene 12743
 28
 0.52
chr10_30618403_30618566 0.36 Hint3
 histidine triad nucleotide binding protein 3
 5
 0.97
chr17_56584499_56584660 0.36 Safb2
 scaffold attachment factor B2
 6
 0.76
chr6_100287706_100287857 0.36 Rybp
 RING1 and YY1 binding protein
 296
 0.89
chr13_23757082_23757302 0.35 H4c2
 H4 clustered histone 2
 179
 0.65
chr8_123065343_123065509 0.35 Spg7
 SPG7, paraplegin matrix AAA peptidase subunit
 50
 0.95
chr11_83964056_83964464 0.35 Synrg
 synergin, gamma
 168
 0.95
chr2_34826169_34826329 0.35 Fbxw2
 F-box and WD-40 domain protein 2
 14
 0.96
chr1_157086221_157086390 0.35 Tex35
 testis expressed 35
 22083
 0.15
chr1_16105755_16105912 0.34 Rdh10
 retinol dehydrogenase 10 (all-trans)
 59
 0.95
chr7_15967498_15967678 0.34 Ehd2
 EH-domain containing 2
 21
 0.95
chr8_79711664_79711818 0.34 Abce1
 ATP-binding cassette, sub-family E (OABP), member 1
 1
 0.55
chr9_118149943_118150094 0.34 Cmc1
 COX assembly mitochondrial protein 1
 145
 0.6
chr19_8735721_8735876 0.34 Wdr74
 WD repeat domain 74
 29
 0.89
chr17_3557456_3557629 0.34 Tfb1m
 transcription factor B1, mitochondrial
 192
 0.61
chr1_36512638_36512794 0.34 Cnnm3
 cyclin M3
 381
 0.72
chr8_11312731_11312901 0.34 Col4a1
 collagen, type IV, alpha 1
 10
 0.49
chr11_57404263_57404414 0.33 Gm12242
 predicted gene 12242
 44769
 0.17
chr2_25272346_25272512 0.33 Ssna1
 SS nuclear autoantigen 1
 9
 0.5
chr9_99243254_99243431 0.33 Cep70
 centrosomal protein 70
 25
 0.77
chr13_23551341_23551537 0.33 H4c6
 H4 clustered histone 6
 209
 0.74
chr6_28215446_28215622 0.33 6530409C15Rik
 RIKEN cDNA 6530409C15 gene
 21
 0.93
chr4_123750282_123750439 0.33 Akirin1
 akirin 1
 15
 0.97
chr5_29195771_29195928 0.33 Rnf32
 ring finger protein 32
 143
 0.97
chr11_73281551_73281730 0.32 Trpv3
 transient receptor potential cation channel, subfamily V, member 3
 14252
 0.1
chr8_127064425_127064598 0.32 Pard3
 par-3 family cell polarity regulator
 164
 0.95
chr16_31948445_31948606 0.32 Ncbp2
 nuclear cap binding protein subunit 2
 12
 0.49
chr7_35318364_35318519 0.32 Gpatch1
 G patch domain containing 1
 1
 0.97
chr9_110266411_110266569 0.32 Gm43622
 predicted gene 43622
 12346
 0.11
chr2_69647092_69647250 0.32 Bbs5
 Bardet-Biedl syndrome 5 (human)
 0
 0.97
chr7_116307395_116307559 0.32 Plekha7
 pleckstrin homology domain containing, family A member 7
 573
 0.66
chr7_119720730_119720890 0.32 Thumpd1
 THUMP domain containing 1
 12
 0.96
chr18_80934002_80934172 0.32 Atp9b
 ATPase, class II, type 9B
 27
 0.97
chr5_88565662_88565841 0.32 Rufy3
 RUN and FYVE domain containing 3
 711
 0.61
chr7_60391337_60391492 0.32 Gm30196
 predicted gene, 30196
 98210
 0.06
chr5_74531693_74531850 0.32 Scfd2
 Sec1 family domain containing 2
 12
 0.98
chr5_114859386_114859551 0.32 Gm9936
 predicted gene 9936
 85
 0.69
chr12_40037787_40037938 0.32 Arl4a
 ADP-ribosylation factor-like 4A
 163
 0.6
chr2_122348624_122348786 0.32 Shf
 Src homology 2 domain containing F
 5426
 0.14
chr3_41742215_41742378 0.31 Sclt1
 sodium channel and clathrin linker 1
 109
 0.76
chr2_60881028_60881212 0.31 Rbms1
 RNA binding motif, single stranded interacting protein 1
 318
 0.93
chr11_6476090_6476255 0.31 Purb
 purine rich element binding protein B
 255
 0.71
chrX_20961951_20962111 0.31 Uxt
 ubiquitously expressed prefoldin like chaperone
 14
 0.55
chr11_53957956_53958400 0.31 Slc22a21
 solute carrier family 22 (organic cation transporter), member 21
 5032
 0.13
chr11_121354408_121354566 0.31 Wdr45b
 WD repeat domain 45B
 42
 0.97
chr4_129742335_129742505 0.31 Khdrbs1
 KH domain containing, RNA binding, signal transduction associated 1
 117
 0.94
chr7_100520780_100520948 0.31 Gm8463
 predicted gene 8463
 3152
 0.12
chr5_113735843_113736024 0.31 Ficd
 FIC domain containing
 130
 0.93
chr8_124751800_124751970 0.31 Fam89a
 family with sequence similarity 89, member A
 53
 0.96
chr3_51560826_51560999 0.31 Setd7
 SET domain containing (lysine methyltransferase) 7
 33
 0.92
chr10_53751073_53751417 0.31 Fam184a
 family with sequence similarity 184, member A
 122
 0.97
chr2_160366069_160366220 0.30 Mafb
 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
 921
 0.67
chr5_106696519_106696703 0.30 Zfp644
 zinc finger protein 644
 14
 0.51
chr11_117072260_117072440 0.30 Snhg20
 small nucleolar RNA host gene 20
 3658
 0.12
chr13_100104015_100104175 0.30 Bdp1
 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
 25
 0.97
chr1_134455392_134455553 0.29 Gm37935
 predicted gene, 37935
 1
 0.52
chr5_76905448_76905617 0.29 Aasdh
 aminoadipate-semialdehyde dehydrogenase
 18
 0.97
chr3_98013379_98013570 0.29 Notch2
 notch 2
 53
 0.98
chr13_23423804_23423964 0.29 Abt1
 activator of basal transcription 1
 18
 0.95
chr17_26561346_26561508 0.29 Ergic1
 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
 62
 0.5
chr11_86807573_86807779 0.29 Dhx40
 DEAH (Asp-Glu-Ala-His) box polypeptide 40
 70
 0.98
chr7_132656702_132656878 0.29 Gm15582
 predicted gene 15582
 3094
 0.23
chr15_64060280_64060431 0.29 Fam49b
 family with sequence similarity 49, member B
 12
 0.98
chr6_128300445_128300614 0.28 Tead4
 TEA domain family member 4
 209
 0.86
chr2_119873217_119873398 0.28 Gm13998
 predicted gene 13998
 5096
 0.17
chr3_101604078_101604260 0.28 Atp1a1
 ATPase, Na+/K+ transporting, alpha 1 polypeptide
 515
 0.77
chr8_22398390_22398541 0.28 Slc25a15
 solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15
 79
 0.72
chr2_157457536_157457702 0.28 Src
 Rous sarcoma oncogene
 534
 0.77
chr2_127584633_127584807 0.28 Zfp661
 zinc finger protein 661
 43
 0.96
chr10_82629543_82629854 0.28 Tdg
 thymine DNA glycosylase
 130
 0.95
chr6_91440858_91441030 0.28 4930471M09Rik
 RIKEN cDNA 4930471M09 gene
 32
 0.5
chr11_102437613_102437783 0.28 Fam171a2
 family with sequence similarity 171, member A2
 2079
 0.16
chr11_113648293_113648452 0.27 Cog1
 component of oligomeric golgi complex 1
 797
 0.48
chr3_87930109_87930271 0.27 Rrnad1
 ribosomal RNA adenine dimethylase domain containing 1
 46
 0.59
chr17_87672565_87672807 0.27 Msh2
 mutS homolog 2
 77
 0.98
chr9_119983715_119983880 0.27 Csrnp1
 cysteine-serine-rich nuclear protein 1
 18
 0.89
chr8_77549121_77549479 0.27 Prmt9
 protein arginine methyltransferase 9
 97
 0.95
chr17_47789741_47789893 0.27 Tfeb
 transcription factor EB
 376
 0.81
chr7_79737777_79737928 0.27 Pex11a
 peroxisomal biogenesis factor 11 alpha
 872
 0.37
chr8_57511296_57511457 0.27 Hmgb2
 high mobility group box 2
 531
 0.63
chr11_115153727_115153896 0.27 Rab37
 RAB37, member RAS oncogene family
 346
 0.8
chr6_113891230_113891419 0.27 Atp2b2
 ATPase, Ca++ transporting, plasma membrane 2
 46
 0.98
chr1_72711174_72711330 0.27 Rpl37a
 ribosomal protein L37a
 38
 0.97
chr16_5049903_5050066 0.27 Ubn1
 ubinuclein 1
 73
 0.56
chr8_20557619_20557786 0.27 Gm21182
 predicted gene, 21182
 216
 0.93
chr7_28278076_28278248 0.26 Eid2b
 EP300 interacting inhibitor of differentiation 2B
 423
 0.66
chr9_67633987_67634159 0.26 Gm47110
 predicted gene, 47110
 66108
 0.09
chr5_48372237_48372392 0.26 5730480H06Rik
 RIKEN cDNA 5730480H06 gene
 15
 0.98
chr9_63398821_63399040 0.26 2300009A05Rik
 RIKEN cDNA 2300009A05 gene
 103
 0.77
chr8_25719944_25720110 0.26 Plpp5
 phospholipid phosphatase 5
 10
 0.95
chr5_130266836_130266987 0.25 Tyw1
 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
 7981
 0.13
chr8_86745528_86745751 0.25 Gm10638
 predicted gene 10638
 60
 0.79
chr10_19015048_19015233 0.25 Tnfaip3
 tumor necrosis factor, alpha-induced protein 3
 236
 0.94
chr11_17953844_17954011 0.25 Etaa1os
 Ewing tumor-associated antigen 1, opposite strand
 43
 0.5
chr15_58135155_58135324 0.25 Atad2
 ATPase family, AAA domain containing 2
 157
 0.93
chr15_59374120_59374279 0.25 Washc5
 WASH complex subunit 5
 32
 0.51
chr9_66158117_66158276 0.25 Dapk2
 death-associated protein kinase 2
 27
 0.98
chr11_77508148_77508326 0.25 Git1
 GIT ArfGAP 1
 3101
 0.14
chr7_74554787_74554949 0.25 Slco3a1
 solute carrier organic anion transporter family, member 3a1
 88
 0.98
chr11_69803793_69804128 0.25 Tmem102
 transmembrane protein 102
 1664
 0.12
chr11_52396312_52396469 0.25 9530068E07Rik
 RIKEN cDNA 9530068E07 gene
 38
 0.97
chr1_189007804_189007963 0.25 Kctd3
 potassium channel tetramerisation domain containing 3
 42
 0.98
chr7_80402754_80402960 0.25 Furin
 furin (paired basic amino acid cleaving enzyme)
 95
 0.93
chr6_131293140_131293327 0.24 Magohb
 mago homolog B, exon junction complex core component
 11
 0.94
chr12_84408979_84409147 0.24 Bbof1
 basal body orientation factor 1
 8
 0.5
chr6_134927326_134927497 0.24 Lockd
 lncRNA downstream of Cdkn1b
 1681
 0.22
chr5_24908509_24908696 0.24 Prkag2
 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
 93
 0.96
chr16_32246842_32247035 0.24 Fbxo45
 F-box protein 45
 220
 0.55
chr4_151996577_151996775 0.24 Phf13
 PHD finger protein 13
 418
 0.72
chr10_62449694_62449858 0.24 Supv3l1
 suppressor of var1, 3-like 1 (S. cerevisiae)
 38
 0.79
chr1_53313553_53313713 0.24 Osgepl1
 O-sialoglycoprotein endopeptidase-like 1
 9
 0.95
chr12_40038017_40038432 0.24 Arl4aos
 ADP-ribosylation factor-like 4A, opposite strand
 125
 0.61
chr13_23760889_23761164 0.24 H4c1
 H4 clustered histone 1
 204
 0.73
chr12_111677976_111678157 0.24 Trmt61a
 tRNA methyltransferase 61A
 39
 0.95
chr12_4907452_4907633 0.24 Ubxn2a
 UBX domain protein 2A
 103
 0.96
chrX_57053455_57053640 0.24 Htatsf1
 HIV TAT specific factor 1
 36
 0.98
chr17_28622423_28622608 0.24 Srpk1
 serine/arginine-rich protein specific kinase 1
 28
 0.96
chr18_10181554_10181776 0.24 Rock1
 Rho-associated coiled-coil containing protein kinase 1
 127
 0.94
chr12_116281041_116281204 0.24 Esyt2
 extended synaptotagmin-like protein 2
 74
 0.93
chr10_21295922_21296083 0.24 Hbs1l
 Hbs1-like (S. cerevisiae)
 7
 0.97
chr5_137601486_137601690 0.24 Gm7285
 predicted gene 7285
 5
 0.87
chr1_57377477_57377640 0.24 4930558J18Rik
 RIKEN cDNA 4930558J18 gene
 14
 0.53
chr5_124579024_124579188 0.23 Eif2b1
 eukaryotic translation initiation factor 2B, subunit 1 (alpha)
 25
 0.5

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Creb1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.4 1.3 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.3 0.8 GO:0035973 aggrephagy(GO:0035973)
0.2 0.8 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 0.6 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.2 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 0.5 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.3 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.1 0.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 0.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.4 GO:0002432 granuloma formation(GO:0002432)
0.1 0.6 GO:0048840 otolith development(GO:0048840)
0.1 0.3 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.3 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.3 GO:1902488 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.1 0.2 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.1 0.4 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.9 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.1 0.3 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.1 0.3 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 0.4 GO:0060431 primary lung bud formation(GO:0060431)
0.1 0.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.3 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.5 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.1 0.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.2 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 0.3 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.2 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.1 0.1 GO:1901859 negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.1 0.3 GO:0000966 RNA 5'-end processing(GO:0000966)
0.1 0.4 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.2 GO:1902564 negative regulation of neutrophil activation(GO:1902564)
0.1 0.5 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.3 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.2 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.2 GO:1903261 regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.1 0.2 GO:0032439 endosome localization(GO:0032439)
0.1 0.2 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.8 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.1 0.1 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.2 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.2 GO:1903416 response to glycoside(GO:1903416)
0.1 0.3 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.1 0.8 GO:0006071 glycerol metabolic process(GO:0006071)
0.1 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.2 GO:0071503 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0045472 response to ether(GO:0045472)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.3 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.0 0.1 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.0 0.1 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.3 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0 0.1 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.2 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.8 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.0 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:1901874 regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.0 0.2 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.2 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 0.1 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.4 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.4 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.0 GO:0061047 positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.3 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0042851 L-alanine metabolic process(GO:0042851)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.4 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.0 0.2 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0 0.1 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.2 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.0 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 0.1 GO:0001806 type IV hypersensitivity(GO:0001806)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.5 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.0 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.0 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.1 GO:1902033 regulation of hematopoietic stem cell proliferation(GO:1902033)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:1902566 regulation of eosinophil degranulation(GO:0043309) regulation of eosinophil activation(GO:1902566)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.0 GO:0015819 lysine transport(GO:0015819)
0.0 0.4 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.0 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.0 0.1 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:2000173 negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.1 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0010534 regulation of activation of JAK2 kinase activity(GO:0010534)
0.0 0.1 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.4 GO:0034508 centromere complex assembly(GO:0034508)
0.0 0.0 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 0.1 GO:0030578 PML body organization(GO:0030578)
0.0 0.1 GO:0003139 secondary heart field specification(GO:0003139)
0.0 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.3 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.3 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.0 0.1 GO:0071316 cellular response to nicotine(GO:0071316)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.0 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.0 GO:0061083 regulation of protein refolding(GO:0061083)
0.0 0.1 GO:0007619 courtship behavior(GO:0007619)
0.0 0.2 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.0 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.2 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.0 0.1 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.0 0.0 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.2 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.1 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0 0.3 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.0 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.0 0.1 GO:0072282 metanephric nephron tubule morphogenesis(GO:0072282)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.0 GO:1990791 dorsal root ganglion development(GO:1990791)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.4 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.0 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0006458 'de novo' protein folding(GO:0006458) 'de novo' posttranslational protein folding(GO:0051084)
0.0 0.1 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0015822 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0 0.1 GO:0048617 embryonic foregut morphogenesis(GO:0048617)
0.0 0.2 GO:0000154 rRNA modification(GO:0000154)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.2 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.0 GO:0019400 alditol metabolic process(GO:0019400)
0.0 0.0 GO:0071440 regulation of histone H3-K14 acetylation(GO:0071440)
0.0 0.0 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.0 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:0015879 carnitine transport(GO:0015879)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.0 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.2 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.0 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0032986 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.0 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
0.0 0.0 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.0 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.2 GO:0006110 regulation of glycolytic process(GO:0006110)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.1 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.0 0.2 GO:0006907 pinocytosis(GO:0006907)
0.0 0.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.1 GO:0033572 transferrin transport(GO:0033572)
0.0 0.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0072666 establishment of protein localization to vacuole(GO:0072666)
0.0 0.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.4 GO:0006611 protein export from nucleus(GO:0006611)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0000814 ESCRT II complex(GO:0000814)
0.2 0.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.2 0.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.2 0.6 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.6 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 0.4 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.5 GO:0030689 Noc complex(GO:0030689)
0.1 0.3 GO:0097452 GAIT complex(GO:0097452)
0.1 0.4 GO:0042827 platelet dense granule(GO:0042827)
0.1 0.3 GO:0033269 internode region of axon(GO:0033269)
0.1 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.4 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 1.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.3 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.6 GO:0043218 compact myelin(GO:0043218)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.0 GO:0043259 laminin-10 complex(GO:0043259)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0045495 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.0 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.6 GO:0044438 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0071565 nBAF complex(GO:0071565)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.0 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 0.0 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 0.8 GO:0004370 glycerol kinase activity(GO:0004370)
0.2 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.2 0.6 GO:0019776 Atg8 ligase activity(GO:0019776)
0.2 0.8 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 1.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.4 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.4 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.4 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.3 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.1 0.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.3 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 0.3 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.4 GO:0043495 protein anchor(GO:0043495)
0.1 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.7 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.3 GO:1990239 steroid hormone binding(GO:1990239)
0.1 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.3 GO:0043559 insulin binding(GO:0043559)
0.1 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 1.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.2 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0018638 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0052687 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0 0.0 GO:0016436 rRNA methyltransferase activity(GO:0008649) rRNA (uridine) methyltransferase activity(GO:0016436)
0.0 0.6 GO:0004119 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0043820 4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.8 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.0 GO:0015181 arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 1.5 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.0 1.2 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:1990188 euchromatin binding(GO:1990188)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.0 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.0 GO:1904680 peptide transmembrane transporter activity(GO:1904680)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.0 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.0 GO:0032564 dATP binding(GO:0032564)
0.0 0.3 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.0 0.0 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.0 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)
0.0 0.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0016443 bidentate ribonuclease III activity(GO:0016443)
0.0 0.4 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.0 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.0 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.1 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 1.3 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.1 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes