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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Creb3l2

Z-value: 2.46

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Transcription factors associated with Creb3l2

Gene Symbol	Gene ID	Gene Info
Creb3l2 Ensembl NCBI MGI UniProt	ENSMUSG00000038648.5	Creb3l2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Creb3l2	chr6_37480097_37480265	38035	0.166799	-0.90	1.5e-02	Click!
Creb3l2	chr6_37431530_37431865	10449	0.271981	-0.88	2.0e-02	Click!
Creb3l2	chr6_37441336_37441654	651	0.801531	0.84	3.7e-02	Click!
Creb3l2	chr6_37426047_37426198	16024	0.258549	-0.79	6.2e-02	Click!
Creb3l2	chr6_37448065_37448224	5998	0.285415	0.78	6.5e-02	Click!

Activity of the Creb3l2 motif across conditions

Conditions sorted by the z-value of the Creb3l2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_112103112_112103298	1.87	Mir128-2	microRNA 128-2	15506	0.25
chr4_138981088_138981239	1.85	Tmco4	transmembrane and coiled-coil domains 4	8254	0.16
chr19_46056737_46057343	1.81	Pprc1	peroxisome proliferative activated receptor, gamma, coactivator-related 1	176	0.92
chr9_60982764_60983106	1.59	Gm5122	predicted gene 5122	30546	0.14
chr2_163515893_163516044	1.41	Gm25881	predicted gene, 25881	1452	0.28
chr10_93077177_93077387	1.40	Cfap54	cilia and flagella associated protein 54	4314	0.23
chr15_62044174_62044346	1.40	Pvt1	Pvt1 oncogene	5003	0.28
chr4_117120836_117121181	1.38	Btbd19	BTB (POZ) domain containing 19	257	0.77
chr2_52298505_52298656	1.37	Gm22095	predicted gene, 22095	15503	0.19
chr18_60848442_60848618	1.36	Tcof1	treacle ribosome biogenesis factor 1	84	0.96
chr4_148591704_148592085	1.32	Srm	spermidine synthase	24	0.95
chr9_106234042_106234256	1.31	Alas1	aminolevulinic acid synthase 1	2935	0.14
chr15_97035420_97035580	1.30	Slc38a4	solute carrier family 38, member 4	4289	0.32
chr9_21367416_21367785	1.27	Ilf3	interleukin enhancer binding factor 3	271	0.81
chr10_77902990_77903176	1.25	Lrrc3	leucine rich repeat containing 3	547	0.54
chr5_64298676_64298855	1.25	Tbc1d1	TBC1 domain family, member 1	235	0.91
chr1_180223322_180223519	1.21	Psen2	presenilin 2	6148	0.15
chr2_174343758_174344168	1.21	Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	349	0.83
chr4_142337823_142337991	1.20	Gm13052	predicted gene 13052	8568	0.28
chr10_59295146_59295479	1.20	P4ha1	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide	27984	0.16
chr5_31094198_31094360	1.20	Slc30a3	solute carrier family 30 (zinc transporter), member 3	522	0.44
chr9_83834067_83834712	1.20	Ttk	Ttk protein kinase	300	0.91
chr2_78656286_78656827	1.19	Gm14463	predicted gene 14463	873	0.71
chr8_93179883_93180034	1.16	Ces1d	carboxylesterase 1D	4669	0.15
chr7_142533086_142533550	1.16	Mrpl23	mitochondrial ribosomal protein L23	156	0.91
chr10_127063341_127063519	1.15	Cdk4	cyclin-dependent kinase 4	104	0.9
chr11_113148197_113148382	1.14	2610035D17Rik	RIKEN cDNA 2610035D17 gene	24788	0.24
chr8_14911524_14911687	1.13	Arhgef10	Rho guanine nucleotide exchange factor (GEF) 10	58	0.97
chr3_52622106_52622284	1.12	Gm10293	predicted pseudogene 10293	9360	0.25
chr11_60199988_60200509	1.12	Mir6921	microRNA 6921	369	0.65
chr3_106482771_106483037	1.12	Dennd2d	DENN/MADD domain containing 2D	454	0.49
chr11_46085325_46085478	1.11	Mir8100	microRNA 8100	16869	0.12
chr10_127373842_127374054	1.10	Inhbc	inhibin beta-C	3517	0.11
chr2_150786904_150787055	1.09	Pygb	brain glycogen phosphorylase	244	0.91
chr8_70551140_70551291	1.08	Ell	elongation factor RNA polymerase II	11527	0.08
chr17_24163699_24163861	1.05	Amdhd2	amidohydrolase domain containing 2	14	0.94
chr9_106238027_106238241	1.05	Alas1	aminolevulinic acid synthase 1	596	0.58
chr5_147071140_147071411	1.03	Lnx2	ligand of numb-protein X 2	5311	0.17
chr2_84840241_84840491	1.03	Slc43a1	solute carrier family 43, member 1	167	0.91
chr12_29894783_29894948	1.03	Myt1l	myelin transcription factor 1-like	249	0.95
chr12_103328324_103328502	1.02	Asb2	ankyrin repeat and SOCS box-containing 2	7171	0.11
chr9_94705088_94705258	1.01	Gm16262	predicted gene 16262	2854	0.25
chr19_20610921_20611108	1.00	Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1	9053	0.22
chr10_128909533_128909836	1.00	Cd63	CD63 antigen	15	0.95
chr11_5899422_5899614	0.99	Myl7	myosin, light polypeptide 7, regulatory	736	0.5
chr17_87570754_87570962	0.98	Gm46587	predicted gene, 46587	796	0.62
chr11_98754743_98754913	0.98	Thra	thyroid hormone receptor alpha	1242	0.28
chr2_168721341_168721659	0.97	Atp9a	ATPase, class II, type 9A	8538	0.2
chr2_155067847_155068055	0.97	Gm45609	predicted gene 45609	6230	0.14
chr10_59149959_59150116	0.96	Septin10	septin 10	28820	0.16
chr9_78154656_78154974	0.95	Cilk1	ciliogenesis associated kinase 1	508	0.69
chr6_139577165_139577358	0.94	4930443G03Rik	RIKEN cDNA 4930443G03 gene	56	0.98
chr3_94412685_94412888	0.94	1700040D17Rik	RIKEN cDNA 1700040D17 gene	133	0.72
chr4_137795816_137796289	0.94	Alpl	alkaline phosphatase, liver/bone/kidney	178	0.96
chr4_149978768_149979375	0.93	H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	22194	0.13
chr17_28517484_28517972	0.93	Fkbp5	FK506 binding protein 5	201	0.84
chr17_24960376_24960530	0.89	Jpt2	Jupiter microtubule associated homolog 2	183	0.91
chr9_24420554_24420746	0.88	Dpy19l1	dpy-19-like 1 (C. elegans)	3309	0.28
chr5_139427163_139427327	0.88	Gper1	G protein-coupled estrogen receptor 1	3965	0.14
chr1_190822997_190823215	0.87	Rps6kc1	ribosomal protein S6 kinase polypeptide 1	10930	0.24
chr4_148168418_148168586	0.86	Fbxo2	F-box protein 2	7881	0.11
chr5_137641169_137641333	0.85	Sap25	sin3 associated polypeptide	83	0.9
chr18_76242274_76242708	0.85	Smad2	SMAD family member 2	317	0.89
chr11_117780625_117780787	0.85	Tmc6	transmembrane channel-like gene family 6	48	0.93
chr7_101085910_101086353	0.84	Fchsd2	FCH and double SH3 domains 2	6732	0.17
chr2_72157539_72157839	0.84	Rapgef4os1	Rap guanine nucleotide exchange factor (GEF) 4, opposite strand 1	8893	0.2
chr10_62833072_62833249	0.84	Tet1	tet methylcytosine dioxygenase 1	18619	0.11
chr12_28700387_28700829	0.84	Trappc12	trafficking protein particle complex 12	1001	0.46
chr11_5909915_5910066	0.83	Gck	glucokinase	5134	0.12
chr14_118040435_118040621	0.83	Dct	dopachrome tautomerase	2601	0.27
chr10_63339095_63339253	0.83	Sirt1	sirtuin 1	139	0.94
chr19_23074772_23074923	0.83	C330002G04Rik	RIKEN cDNA C330002G04 gene	1006	0.54
chr1_75142621_75142779	0.83	Cnppd1	cyclin Pas1/PHO80 domain containing 1	3	0.54
chr8_80821631_80821838	0.82	Gab1	growth factor receptor bound protein 2-associated protein 1	9150	0.2
chr8_105798853_105799004	0.82	Ranbp10	RAN binding protein 10	28277	0.08
chr3_132815131_132815356	0.82	Gm42876	predicted gene 42876	8990	0.14
chr5_4960222_4960441	0.82	Gm22897	predicted gene, 22897	24906	0.18
chr11_117341816_117342087	0.79	Septin9	septin 9	9523	0.19
chr7_141293897_141294068	0.79	Drd4	dopamine receptor D4	851	0.35
chr19_20726917_20727068	0.78	Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7	570	0.83
chr6_108140829_108140991	0.78	Rpl36-ps12	ribosomal protein L36, pseudogene 12	401	0.86
chr10_80340392_80340718	0.77	Adamtsl5	ADAMTS-like 5	470	0.56
chr9_74850759_74851075	0.77	Gm16551	predicted gene 16551	1922	0.24
chr6_140368798_140368983	0.77	n-R5s168	nuclear encoded rRNA 5S 168	49260	0.11
chr16_97913947_97914098	0.77	C2cd2	C2 calcium-dependent domain containing 2	8584	0.18
chr5_66135628_66135793	0.76	Rbm47	RNA binding motif protein 47	15246	0.11
chr7_24928137_24928288	0.76	Arhgef1	Rho guanine nucleotide exchange factor (GEF) 1	4849	0.1
chr1_105998118_105998303	0.75	Zcchc2	zinc finger, CCHC domain containing 2	5912	0.17
chr1_51878776_51878948	0.74	Gm28323	predicted gene 28323	746	0.61
chr9_113122162_113122366	0.74	Gm36251	predicted gene, 36251	765	0.76
chr11_28698214_28698534	0.74	2810471M01Rik	RIKEN cDNA 2810471M01 gene	16810	0.16
chr4_148038831_148039191	0.74	Mthfr	methylenetetrahydrofolate reductase	66	0.66
chr18_75675824_75676322	0.73	Ctif	CBP80/20-dependent translation initiation factor	21481	0.23
chr4_144917193_144917364	0.73	Dhrs3	dehydrogenase/reductase (SDR family) member 3	1601	0.41
chr17_28812253_28812687	0.73	Brpf3	bromodomain and PHD finger containing, 3	1919	0.2
chr1_171195959_171196110	0.73	Pcp4l1	Purkinje cell protein 4-like 1	234	0.84
chr2_27572911_27573062	0.73	Gm13421	predicted gene 13421	32557	0.13
chr7_123196570_123196734	0.72	Tnrc6a	trinucleotide repeat containing 6a	16731	0.19
chr11_70000432_70000600	0.71	Dvl2	dishevelled segment polarity protein 2	79	0.9
chr19_44405361_44405580	0.71	Scd1	stearoyl-Coenzyme A desaturase 1	1220	0.39
chr10_78426542_78426693	0.70	Cstb	cystatin B	948	0.28
chr6_90568565_90568716	0.70	Aldh1l1	aldehyde dehydrogenase 1 family, member L1	934	0.49
chr10_117145636_117145926	0.70	Frs2	fibroblast growth factor receptor substrate 2	2714	0.21
chr2_173159829_173160580	0.69	Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	7122	0.18
chr8_120113112_120113406	0.69	6430548M08Rik	RIKEN cDNA 6430548M08 gene	893	0.44
chr19_44985600_44985928	0.69	4930414N06Rik	RIKEN cDNA 4930414N06 gene	1214	0.29
chr11_60196530_60196694	0.69	Mir6921	microRNA 6921	4005	0.13
chr8_111854325_111854488	0.69	Cfdp1	craniofacial development protein 1	115	0.96
chr9_102732818_102732969	0.69	Amotl2	angiomotin-like 2	2162	0.21
chr11_75769198_75769770	0.68	Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	17880	0.14
chr15_83349552_83350074	0.68	Arfgap3	ADP-ribosylation factor GTPase activating protein 3	361	0.84
chr8_41069792_41069999	0.68	Mtus1	mitochondrial tumor suppressor 1	12881	0.16
chr12_103949173_103949487	0.68	Serpina1e	serine (or cysteine) peptidase inhibitor, clade A, member 1E	7568	0.11
chr3_157912600_157912930	0.67	Cth	cystathionase (cystathionine gamma-lyase)	7040	0.14
chr10_20148225_20148689	0.67	Map7	microtubule-associated protein 7	14	0.98
chr14_59200883_59201288	0.67	Rcbtb1	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1	124	0.96
chr8_116268180_116268552	0.67	4930422C21Rik	RIKEN cDNA 4930422C21 gene	80997	0.1
chr11_51584956_51585449	0.67	Phykpl	5-phosphohydroxy-L-lysine phospholyase	391	0.8
chr3_152396303_152396479	0.66	Zzz3	zinc finger, ZZ domain containing 3	259	0.84
chr17_31521089_31521268	0.66	Ndufv3	NADH:ubiquinone oxidoreductase core subunit V3	993	0.26
chr9_58582090_58582367	0.66	Nptn	neuroplastin	12	0.98
chr12_55831200_55831355	0.66	Brms1l	breast cancer metastasis-suppressor 1-like	5047	0.15
chr7_19877096_19877247	0.66	Gm44659	predicted gene 44659	5733	0.08
chr3_133544844_133545488	0.65	Tet2	tet methylcytosine dioxygenase 2	27	0.53
chr15_76227819_76227970	0.65	Plec	plectin	1603	0.17
chr11_81370078_81370386	0.64	4930527B05Rik	RIKEN cDNA 4930527B05 gene	14781	0.29
chr5_121338798_121338949	0.64	Gm24671	predicted gene, 24671	17971	0.11
chr12_84970404_84970739	0.64	Arel1	apoptosis resistant E3 ubiquitin protein ligase 1	253	0.56
chr6_128438925_128439109	0.64	Gm10069	predicted gene 10069	260	0.53
chr2_144369139_144369688	0.64	Kat14	lysine acetyltransferase 14	414	0.43
chr5_9032304_9032484	0.63	Gm40264	predicted gene, 40264	2386	0.22
chr11_120627879_120628086	0.62	Mafg	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)	2166	0.09
chr11_119258845_119259008	0.62	Ccdc40	coiled-coil domain containing 40	1	0.96
chr14_70443158_70443325	0.62	Polr3d	polymerase (RNA) III (DNA directed) polypeptide D	49	0.76
chr17_56233947_56234106	0.61	Gm49879	predicted gene, 49879	4883	0.1
chr9_57439182_57439333	0.61	Ppcdc	phosphopantothenoylcysteine decarboxylase	834	0.49
chr17_86144597_86145055	0.61	Srbd1	S1 RNA binding domain 1	349	0.89
chr16_17922186_17922530	0.61	AA914427	EST AA914427	315	0.77
chr18_60243095_60243283	0.60	Gm5970	predicted gene 5970	22346	0.13
chr13_90089026_90089404	0.60	Tmem167	transmembrane protein 167	92	0.56
chr8_123232613_123232964	0.60	Gm45842	predicted gene 45842	1989	0.12
chr13_43252482_43252652	0.59	Gfod1	glucose-fructose oxidoreductase domain containing 1	50838	0.13
chr15_34238004_34238174	0.59	Laptm4b	lysosomal-associated protein transmembrane 4B	60	0.97
chr10_68094854_68095005	0.58	Arid5b	AT rich interactive domain 5B (MRF1-like)	41697	0.15
chr9_87255292_87255453	0.58	Cep162	centrosomal protein 162	84	0.98
chr2_31477009_31477347	0.58	Ass1	argininosuccinate synthetase 1	6971	0.19
chr2_164073997_164074164	0.58	Stk4	serine/threonine kinase 4	58	0.96
chr5_137314174_137314330	0.58	Trip6	thyroid hormone receptor interactor 6	45	0.93
chr13_51946235_51946429	0.58	Gm26651	predicted gene, 26651	26882	0.2
chr9_120492375_120492774	0.57	D830035M03Rik	RIKEN cDNA D830035M03 gene	27	0.55
chr14_70351384_70351576	0.57	Slc39a14	solute carrier family 39 (zinc transporter), member 14	55	0.96
chr11_62557761_62557924	0.57	Ubb	ubiquitin B	6166	0.09
chr3_21936262_21936525	0.55	Gm43674	predicted gene 43674	62075	0.12
chr9_103761868_103762039	0.55	Tmem108	transmembrane protein 108	116	0.98
chr10_99209224_99209646	0.55	Gm34574	predicted gene, 34574	13631	0.11
chr6_9078648_9078799	0.55	Gm35736	predicted gene, 35736	68043	0.14
chr2_121449025_121449188	0.54	Serf2	small EDRK-rich factor 2	89	0.9
chr6_8209868_8210031	0.54	Mios	meiosis regulator for oocyte development	727	0.65
chr4_154864284_154864460	0.54	Ttc34	tetratricopeptide repeat domain 34	3820	0.16
chr2_167496630_167496810	0.53	Spata2	spermatogenesis associated 2	3833	0.16
chr2_180725008_180725370	0.53	Slc17a9	solute carrier family 17, member 9	74	0.95
chr13_21171668_21171974	0.53	Trim27	tripartite motif-containing 27	7624	0.14
chr17_22361357_22361742	0.53	Zfp758	zinc finger protein 758	27	0.65
chr3_40540672_40540830	0.53	Intu	inturned planar cell polarity protein	16	0.98
chr11_69088418_69088577	0.53	Vamp2	vesicle-associated membrane protein 2	7	0.93
chr19_25542114_25542287	0.52	Dmrt1	doublesex and mab-3 related transcription factor 1	36493	0.15
chr10_95685288_95685475	0.52	Anapc15-ps	anaphase promoting complex C subunit 15, pseudogene	11930	0.11
chr5_110102038_110102206	0.52	Plcxd1	phosphatidylinositol-specific phospholipase C, X domain containing 1	918	0.36
chr4_109419168_109419344	0.51	Ttc39a	tetratricopeptide repeat domain 39A	1686	0.32
chr3_116236671_116236856	0.51	Gpr88	G-protein coupled receptor 88	16326	0.17
chr5_72168137_72168298	0.51	Commd8	COMM domain containing 8	28	0.98
chr9_63989489_63989681	0.51	Smad6	SMAD family member 6	27402	0.13
chr17_80625437_80625624	0.50	Map4k3	mitogen-activated protein kinase kinase kinase kinase 3	544	0.81
chr2_170007586_170007998	0.50	AY702102	cDNA sequence AY702102	44605	0.18
chr7_123186591_123187282	0.50	Tnrc6a	trinucleotide repeat containing 6a	7015	0.22
chr16_84955565_84955728	0.50	App	amyloid beta (A4) precursor protein	7735	0.18
chr7_128617191_128617383	0.50	Inpp5f	inositol polyphosphate-5-phosphatase F	5927	0.13
chr3_138221221_138221499	0.50	Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	111	0.95
chr5_123172881_123173032	0.50	Hpd	4-hydroxyphenylpyruvic acid dioxygenase	45	0.94
chrX_42013544_42013707	0.50	Xiap	X-linked inhibitor of apoptosis	46054	0.13
chr14_58788638_58788797	0.49	Gm9022	predicted gene 9022	90598	0.08
chrX_163908846_163909025	0.49	Ap1s2	adaptor-related protein complex 1, sigma 2 subunit	82	0.98
chr11_94653911_94654072	0.49	Mrpl27	mitochondrial ribosomal protein L27	20	0.49
chr6_52172625_52172818	0.49	Gm15050	predicted gene 15050	160	0.83
chr9_106369294_106369462	0.49	Dusp7	dual specificity phosphatase 7	234	0.89
chr15_85337324_85337483	0.48	Atxn10	ataxin 10	1158	0.51
chr9_53596608_53596772	0.48	Acat1	acetyl-Coenzyme A acetyltransferase 1	12933	0.14
chr1_134419856_134420043	0.48	Adipor1	adiponectin receptor 1	4385	0.12
chr11_117072260_117072440	0.48	Snhg20	small nucleolar RNA host gene 20	3658	0.12
chr5_74401642_74401799	0.48	Scfd2	Sec1 family domain containing 2	3982	0.2
chr13_23526499_23526651	0.48	Gm11335	predicted gene 11335	4368	0.06
chr13_47014530_47014726	0.48	Nhlrc1	NHL repeat containing 1	222	0.86
chr2_17644701_17644889	0.48	Mir6419	microRNA 6419	81281	0.09
chr13_101746510_101746927	0.48	Gm36638	predicted gene, 36638	5170	0.24
chr6_115804879_115805037	0.48	Snora7a	small nucleolar RNA, H/ACA box 7A	3156	0.12
chr18_5010031_5010219	0.47	Svil	supervillin	15189	0.28
chr7_111122949_111123134	0.47	1700012D14Rik	RIKEN cDNA 1700012D14 gene	357	0.84
chr6_101377687_101377878	0.47	Pdzrn3	PDZ domain containing RING finger 3	115	0.96
chr13_23504004_23504163	0.47	n-TStga1	nuclear encoded tRNA serine 1 (anticodon TGA)	14059	0.05
chr6_118479189_118479349	0.46	Zfp9	zinc finger protein 9	51	0.97

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Creb3l2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
0.3	0.8	GO:1904179	positive regulation of adipose tissue development(GO:1904179)
0.3	0.8	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.3	1.0	GO:0010288	response to lead ion(GO:0010288)
0.2	0.9	GO:2000680	regulation of rubidium ion transport(GO:2000680)
0.2	0.6	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.2	1.0	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.2	0.6	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2	0.5	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2	0.5	GO:0006068	ethanol catabolic process(GO:0006068)
0.2	0.7	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2	0.3	GO:2000619	negative regulation of histone H4-K16 acetylation(GO:2000619)
0.2	0.5	GO:0070827	chromatin maintenance(GO:0070827)
0.2	0.6	GO:0014022	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2	0.8	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.1	1.3	GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1	0.4	GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.1	0.5	GO:0043308	eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.1	0.4	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.1	0.4	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
0.1	0.5	GO:0019388	galactose catabolic process(GO:0019388)
0.1	0.6	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.1	0.3	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1	0.3	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.1	0.2	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.1	0.5	GO:1903887	motile primary cilium assembly(GO:1903887)
0.1	0.5	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.1	0.5	GO:0006572	tyrosine catabolic process(GO:0006572)
0.1	0.3	GO:1905216	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.1	0.4	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.3	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.1	0.5	GO:0097501	stress response to metal ion(GO:0097501)
0.1	0.8	GO:0006228	UTP biosynthetic process(GO:0006228)
0.1	0.3	GO:0008050	female courtship behavior(GO:0008050)
0.1	0.2	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1	0.4	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
0.1	0.6	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.1	0.2	GO:0072429	response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1	0.5	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.1	0.2	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.1	0.4	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1	0.3	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1	0.1	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.1	0.2	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.1	0.3	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.1	0.4	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.1	0.3	GO:0008355	olfactory learning(GO:0008355)
0.1	0.2	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	0.2	GO:0001543	ovarian follicle rupture(GO:0001543)
0.1	0.2	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1	0.3	GO:0098535	de novo centriole assembly(GO:0098535)
0.1	0.3	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1	0.2	GO:0032741	positive regulation of interleukin-18 production(GO:0032741)
0.1	0.2	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.1	0.3	GO:0006824	cobalt ion transport(GO:0006824)
0.1	1.0	GO:0009251	glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1	1.1	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.1	0.2	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1	0.3	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.1	0.4	GO:1903441	protein localization to ciliary membrane(GO:1903441)
0.1	0.1	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1	0.2	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1	0.4	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.2	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.1	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.1	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.1	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0	0.2	GO:1903964	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.1	GO:0009202	deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.0	0.5	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.1	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0	0.9	GO:0042573	retinoic acid metabolic process(GO:0042573)
0.0	1.1	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.1	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.0	0.2	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.3	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.2	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.4	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.1	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.0	0.3	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.2	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.0	0.2	GO:0032532	regulation of microvillus length(GO:0032532)
0.0	0.2	GO:1905063	regulation of vascular smooth muscle cell differentiation(GO:1905063) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.0	0.2	GO:0032811	negative regulation of epinephrine secretion(GO:0032811)
0.0	0.2	GO:0009115	xanthine catabolic process(GO:0009115)
0.0	0.9	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.1	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.2	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	1.3	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.0	0.1	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0	0.2	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.0	0.1	GO:0071873	response to norepinephrine(GO:0071873)
0.0	0.1	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0	0.1	GO:2000152	regulation of ubiquitin-specific protease activity(GO:2000152)
0.0	0.1	GO:0031508	pericentric heterochromatin assembly(GO:0031508)
0.0	0.1	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.5	GO:0006465	signal peptide processing(GO:0006465)
0.0	1.2	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.0	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
0.0	0.2	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.0	0.1	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0	0.2	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.1	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.0	0.2	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	0.1	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.1	GO:0060331	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.4	GO:0033866	nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0	0.2	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.6	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.3	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0	0.3	GO:0038166	angiotensin-activated signaling pathway(GO:0038166)
0.0	0.1	GO:0090310	negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0	0.5	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.2	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:0014858	positive regulation of skeletal muscle cell proliferation(GO:0014858)
0.0	0.1	GO:0045472	response to ether(GO:0045472)
0.0	0.1	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.0	0.2	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.0	0.2	GO:0051256	mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0	0.1	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	1.3	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.1	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.3	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.0	0.1	GO:1901662	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0	0.1	GO:0051031	tRNA transport(GO:0051031)
0.0	0.1	GO:0002741	positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.0	0.2	GO:0060693	regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0	0.2	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.2	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.3	GO:0060294	cilium movement involved in cell motility(GO:0060294)
0.0	0.2	GO:0009650	UV protection(GO:0009650)
0.0	0.1	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.0	0.1	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.0	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.3	GO:0032793	positive regulation of CREB transcription factor activity(GO:0032793)
0.0	0.1	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.1	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.0	GO:0048696	regulation of collateral sprouting in absence of injury(GO:0048696)
0.0	0.0	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.0	0.6	GO:0019432	triglyceride biosynthetic process(GO:0019432)
0.0	0.1	GO:0042939	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0	0.1	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.0	0.1	GO:0060613	fat pad development(GO:0060613)
0.0	0.1	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	0.0	GO:0030421	defecation(GO:0030421)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.2	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.0	0.0	GO:2000974	negative regulation of pro-B cell differentiation(GO:2000974)
0.0	0.1	GO:0006548	histidine metabolic process(GO:0006547) histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.0	GO:1902730	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0	0.5	GO:0036465	synaptic vesicle recycling(GO:0036465)
0.0	1.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.3	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.1	GO:0001828	inner cell mass cellular morphogenesis(GO:0001828)
0.0	0.1	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.1	GO:2000188	regulation of cholesterol homeostasis(GO:2000188)
0.0	0.5	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.1	GO:0009162	deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0	0.3	GO:0045836	positive regulation of meiotic nuclear division(GO:0045836)
0.0	0.1	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.1	GO:2001275	positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0	0.1	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.1	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0	0.2	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.0	0.1	GO:0014053	negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.0	0.1	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.0	0.0	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0	0.1	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.0	0.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.0	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.3	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	0.5	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.1	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.0	GO:0090187	positive regulation of pancreatic juice secretion(GO:0090187)
0.0	0.1	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.0	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.0	0.0	GO:0035483	gastric motility(GO:0035482) gastric emptying(GO:0035483)
0.0	0.0	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.1	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.0	0.0	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.0	GO:2000392	regulation of lamellipodium morphogenesis(GO:2000392)
0.0	0.1	GO:0002636	positive regulation of germinal center formation(GO:0002636)
0.0	0.1	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0034627	'de novo' NAD biosynthetic process(GO:0034627)
0.0	0.0	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.0	GO:0048102	autophagic cell death(GO:0048102)
0.0	0.1	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.0	1.0	GO:0051304	chromosome separation(GO:0051304)
0.0	0.1	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.0	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.1	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.0	0.2	GO:0035278	miRNA mediated inhibition of translation(GO:0035278)
0.0	0.1	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.0	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.1	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.0	0.1	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.3	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.0	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.0	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.1	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0	0.0	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
0.0	0.1	GO:1904587	glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.3	GO:0061512	protein localization to cilium(GO:0061512)
0.0	0.2	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.1	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.1	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.0	GO:1902534	single-organism membrane invagination(GO:1902534)
0.0	0.0	GO:0060264	regulation of respiratory burst involved in inflammatory response(GO:0060264)
0.0	0.1	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0	0.1	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.1	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.1	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.0	0.0	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0	0.2	GO:0043046	DNA methylation involved in gamete generation(GO:0043046)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.3	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.1	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0	0.0	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.0	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.0	GO:1903333	negative regulation of protein folding(GO:1903333)
0.0	0.1	GO:0036089	cleavage furrow formation(GO:0036089)
0.0	0.0	GO:0043096	purine nucleobase salvage(GO:0043096)
0.0	0.1	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
0.0	0.1	GO:0001765	membrane raft assembly(GO:0001765)
0.0	0.0	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.0	GO:0007208	phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.0	0.1	GO:0060283	negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0	0.0	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0	0.0	GO:0006285	base-excision repair, AP site formation(GO:0006285)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.0	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.1	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.0	GO:0006901	vesicle coating(GO:0006901)
0.0	0.0	GO:1900157	regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.0	GO:1900377	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0	0.2	GO:0042772	DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0	0.1	GO:0032875	regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.0	0.0	GO:0040033	negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0	0.0	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0	0.0	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.2	GO:0019430	removal of superoxide radicals(GO:0019430)
0.0	0.0	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0	0.1	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	0.0	GO:0019471	4-hydroxyproline metabolic process(GO:0019471)
0.0	0.0	GO:0033210	leptin-mediated signaling pathway(GO:0033210)
0.0	0.0	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.0	0.1	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.0	0.1	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.0	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.1	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.4	GO:1904029	regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0	0.4	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.3	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0015936	coenzyme A metabolic process(GO:0015936)
0.0	0.0	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.0	0.0	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.0	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.0	GO:0010886	positive regulation of cholesterol storage(GO:0010886)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.3	0.8	GO:0032444	activin responsive factor complex(GO:0032444)
0.2	0.6	GO:0005879	axonemal microtubule(GO:0005879)
0.2	0.8	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	0.4	GO:1990812	growth cone filopodium(GO:1990812)
0.1	0.5	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1	0.3	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1	0.3	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	0.3	GO:0032010	phagolysosome(GO:0032010)
0.1	0.3	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.1	0.3	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.1	0.3	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1	0.3	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.1	0.9	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.1	0.2	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1	0.3	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1	0.7	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1	0.2	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1	1.0	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.2	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.0	0.3	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.2	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	1.4	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.4	GO:0001527	microfibril(GO:0001527)
0.0	0.2	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.0	0.3	GO:0061700	GATOR2 complex(GO:0061700)
0.0	1.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.2	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.6	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.1	GO:0070939	Dsl1p complex(GO:0070939)
0.0	0.4	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.0	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.1	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.0	0.2	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.2	GO:0045180	basal cortex(GO:0045180)
0.0	0.1	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.2	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.2	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.2	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.2	GO:0032009	early phagosome(GO:0032009)
0.0	0.2	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.2	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.2	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.2	GO:0033263	CORVET complex(GO:0033263)
0.0	0.1	GO:0000805	X chromosome(GO:0000805)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0035363	histone locus body(GO:0035363)
0.0	0.3	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.3	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.5	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.1	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.0	0.6	GO:0031672	A band(GO:0031672)
0.0	0.1	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.0	GO:0019815	B cell receptor complex(GO:0019815)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.2	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.3	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.0	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.0	0.0	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.7	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.0	GO:0043293	apoptosome(GO:0043293)
0.0	0.3	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.0	GO:0098827	endoplasmic reticulum subcompartment(GO:0098827)
0.0	0.5	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139)
0.0	0.0	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.0	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.0	GO:1990246	uniplex complex(GO:1990246)
0.0	0.0	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.2	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.2	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.2	GO:0015030	Cajal body(GO:0015030)
0.0	0.1	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.2	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.3	0.9	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3	1.1	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.3	0.8	GO:0043398	HLH domain binding(GO:0043398)
0.2	0.9	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.2	1.0	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.2	0.5	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2	0.5	GO:0019776	Atg8 ligase activity(GO:0019776)
0.1	0.8	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1	0.4	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.1	0.4	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.1	0.3	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1	0.4	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.1	0.3	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1	0.5	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.1	0.3	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.1	0.3	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1	0.4	GO:0047105	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.1	0.4	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1	0.4	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	0.5	GO:0004673	protein histidine kinase activity(GO:0004673)
0.1	0.3	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.3	GO:0005534	galactose binding(GO:0005534)
0.1	0.4	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.1	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	0.2	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.1	0.2	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1	0.2	GO:0032767	copper-dependent protein binding(GO:0032767)
0.1	0.3	GO:0004945	angiotensin type II receptor activity(GO:0004945)
0.1	0.3	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.1	0.3	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.1	0.2	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.1	0.2	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1	0.3	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.2	GO:0016623	aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1	0.2	GO:0004849	uridine kinase activity(GO:0004849)
0.1	0.4	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.3	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.9	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	0.2	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1	0.3	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.1	0.3	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	0.2	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.2	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.2	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0	0.2	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.0	0.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.2	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	1.8	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	1.2	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	0.8	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.0	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.0	0.2	GO:0031779	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.1	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.6	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.4	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.4	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.6	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.1	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.4	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	1.4	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	0.6	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.3	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.2	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0030572	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.5	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	1.2	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	1.0	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0016453	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0	0.2	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.5	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.2	GO:0016936	galactoside binding(GO:0016936)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.8	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.0	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.6	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.2	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.0	0.1	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.3	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.1	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.1	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.2	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.2	GO:0005351	sugar:proton symporter activity(GO:0005351)
0.0	0.1	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.7	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.5	GO:0080031	prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.5	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.1	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	1.0	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.1	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.6	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.0	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.2	GO:0044466	2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.0	0.1	GO:0001164	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.2	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.4	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.3	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.2	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0070635	single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.0	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.0	GO:0016015	morphogen activity(GO:0016015)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.2	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.0	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.0	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.0	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.8	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.0	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.0	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.0	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.0	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.6	GO:0042281	dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281)
0.0	2.0	GO:0008766	UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.0	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.1	GO:0015215	nucleotide transmembrane transporter activity(GO:0015215)
0.0	0.0	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0	0.6	GO:0008565	protein transporter activity(GO:0008565)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.8	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.5	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.6	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.8	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.4	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	1.0	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.9	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	1.4	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.3	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.9	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.4	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.3	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.0	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.5	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.0	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.5	PID P73PATHWAY	p73 transcription factor network
0.0	0.2	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.4	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.0	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.3	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	1.0	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	1.0	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	0.5	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	1.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	0.8	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	0.7	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	1.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	1.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.9	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	1.2	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.4	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.4	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	1.0	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.5	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.6	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.2	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.5	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.3	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.5	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.1	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.6	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.1	REACTOME CELL CYCLE CHECKPOINTS	Genes involved in Cell Cycle Checkpoints
0.0	0.1	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.3	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.1	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery