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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for E2f1

Z-value: 1.89

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Transcription factors associated with E2f1

Gene Symbol	Gene ID	Gene Info
E2f1 Ensembl NCBI MGI UniProt	ENSMUSG00000027490.11	E2F transcription factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_154584077_154584353	E2f1	14323	0.095175	0.84	3.5e-02	Click!
chr2_154585868_154586214	E2f1	16149	0.092810	0.80	5.8e-02	Click!
chr2_154570264_154570435	E2f1	457	0.695875	0.78	6.6e-02	Click!
chr2_154585580_154585751	E2f1	15773	0.093298	0.69	1.3e-01	Click!
chr2_154585359_154585533	E2f1	15554	0.093582	0.55	2.6e-01	Click!

Activity of the E2f1 motif across conditions

Conditions sorted by the z-value of the E2f1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_28886991_28887442	2.58	Gm48080	predicted gene, 48080	834	0.6
chr17_32493567_32493723	1.07	Cyp4f39	cytochrome P450, family 4, subfamily f, polypeptide 39	1487	0.3
chr16_20621460_20621649	0.81	Camk2n2	calcium/calmodulin-dependent protein kinase II inhibitor 2	267	0.75
chr9_65333970_65334121	0.73	Gm39363	predicted gene, 39363	1525	0.2
chr6_47453879_47454048	0.68	Cul1	cullin 1	59	0.83
chr7_46795972_46796137	0.65	Hps5	HPS5, biogenesis of lysosomal organelles complex 2 subunit 2	10	0.51
chr1_182495703_182495872	0.64	Gm37069	predicted gene, 37069	1631	0.28
chr11_4104740_4104947	0.60	Gm11955	predicted gene 11955	2912	0.12
chr17_28523067_28523337	0.57	Gm20109	predicted gene, 20109	54	0.53
chr9_110246098_110246279	0.56	Cspg5	chondroitin sulfate proteoglycan 5	123	0.94
chr6_145767466_145768203	0.54	Rassf8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8	17263	0.18
chr2_154436614_154436770	0.53	Cbfa2t2	CBFA2/RUNX1 translocation partner 2	150	0.95
chr8_124751800_124751970	0.52	Fam89a	family with sequence similarity 89, member A	53	0.96
chr6_121865645_121865799	0.52	Mug1	murinoglobulin 1	19855	0.18
chr1_135375014_135375173	0.51	Shisa4	shisa family member 4	16	0.96
chr1_120111811_120112043	0.51	Dbi	diazepam binding inhibitor	8211	0.18
chr13_51992355_51992528	0.51	Gm26651	predicted gene, 26651	19227	0.2
chr1_136781576_136781746	0.46	Gm8762	predicted gene 8762	7859	0.14
chr11_119913957_119914303	0.44	Chmp6	charged multivesicular body protein 6	115	0.95
chr10_40301571_40301722	0.44	Amd1	S-adenosylmethionine decarboxylase 1	70	0.95
chr7_116039656_116039813	0.44	1110004F10Rik	RIKEN cDNA 1110004F10 gene	22	0.95
chr16_10989648_10989826	0.43	Litaf	LPS-induced TN factor	3334	0.14
chr1_78511963_78512114	0.43	BC035947	cDNA sequence BC035947	120	0.57
chr13_98352948_98353139	0.42	Foxd1	forkhead box D1	1199	0.4
chr2_28840041_28840192	0.42	Gtf3c4	general transcription factor IIIC, polypeptide 4	170	0.65
chr8_122550942_122551215	0.42	Piezo1	piezo-type mechanosensitive ion channel component 1	251	0.84
chr17_35861076_35861404	0.41	Nrm	nurim (nuclear envelope membrane protein)	78	0.9
chr18_39693461_39693788	0.41	Gm50398	predicted gene, 50398	32747	0.16
chr6_83473330_83473495	0.41	Dguok	deoxyguanosine kinase	13598	0.11
chr16_32670450_32670601	0.41	Tnk2	tyrosine kinase, non-receptor, 2	1132	0.39
chr8_13889986_13890137	0.40	Coprs	coordinator of PRMT5, differentiation stimulator	71	0.95
chr12_64918124_64918389	0.39	Gm527	predicted gene 527	287	0.89
chr10_61719422_61719586	0.37	Aifm2	apoptosis-inducing factor, mitochondrion-associated 2	1145	0.39
chr1_133508090_133508255	0.37	Gm8596	predicted gene 8596	21307	0.18
chr13_47105847_47106030	0.37	Dek	DEK oncogene (DNA binding)	108	0.84
chr3_90465954_90466142	0.37	Npr1	natriuretic peptide receptor 1	182	0.87
chr15_78803027_78803209	0.37	Card10	caspase recruitment domain family, member 10	76	0.95
chr4_53440696_53440847	0.36	Slc44a1	solute carrier family 44, member 1	87	0.98
chr1_43827441_43827643	0.36	Uxs1	UDP-glucuronate decarboxylase 1	199	0.93
chr13_23761471_23761669	0.36	H4c1	H4 clustered histone 1	340	0.53
chr14_61173133_61173377	0.35	Sacs	sacsin	265	0.93
chr7_112208684_112208908	0.35	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	17060	0.24
chr1_51815131_51815349	0.35	Myo1b	myosin IB	5306	0.21
chr11_96075628_96076164	0.35	Atp5g1	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)	226	0.86
chr15_76369014_76369269	0.35	Hgh1	HGH1 homolog	243	0.79
chr4_63215885_63216054	0.35	Col27a1	collagen, type XXVII, alpha 1	534	0.76
chr10_63339095_63339253	0.34	Sirt1	sirtuin 1	139	0.94
chr9_15357682_15357986	0.34	Cep295	centrosomal protein 295	46	0.92
chr1_136893539_136893740	0.34	Nr5a2	nuclear receptor subfamily 5, group A, member 2	46944	0.13
chr17_63863193_63863441	0.34	Fer	fer (fms/fps related) protein kinase	255	0.71
chr10_122986042_122986255	0.33	D630033A02Rik	RIKEN cDNA D630033A02 gene	317	0.58
chr8_84872118_84872282	0.33	Syce2	synaptonemal complex central element protein 2	7	0.93
chr11_61342814_61342965	0.33	Slc47a2	solute carrier family 47, member 2	29	0.97
chr14_115040574_115040725	0.33	Mir17hg	Mir17 host gene (non-protein coding)	2230	0.14
chr4_45470057_45470208	0.33	Shb	src homology 2 domain-containing transforming protein B	12670	0.16
chr11_116110160_116110352	0.33	Trim47	tripartite motif-containing 47	10	0.95
chr18_74065170_74065346	0.32	Mapk4	mitogen-activated protein kinase 4	101	0.58
chr5_23787298_23787449	0.32	Rint1	RAD50 interactor 1	338	0.77
chr6_72788306_72788457	0.32	Tcf7l1	transcription factor 7 like 1 (T cell specific, HMG box)	217	0.93
chr8_84011360_84011540	0.32	Misp3	MISP family member 3	39	0.66
chr10_67051361_67051540	0.32	Reep3	receptor accessory protein 3	14128	0.18
chr2_163419076_163419281	0.32	Oser1	oxidative stress responsive serine rich 1	34	0.91
chr5_125441019_125441180	0.31	Bri3bp	Bri3 binding protein	469	0.7
chr1_181475926_181476204	0.31	Ccdc121	coiled-coil domain containing 121	35386	0.14
chr17_29050362_29051086	0.31	Gm41556	predicted gene, 41556	2612	0.13
chr9_22467821_22467972	0.31	Rp9	retinitis pigmentosa 9 (human)	274	0.86
chr6_134929015_134929166	0.31	Lockd	lncRNA downstream of Cdkn1b	2	0.94
chr18_44381017_44381212	0.31	Dcp2	decapping mRNA 2	587	0.78
chr12_69372296_69372449	0.31	Gm9887	predicted gene 9887	86	0.68
chr11_80476499_80476662	0.31	Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	443	0.82
chr1_88491899_88492050	0.31	Glrp1	glutamine repeat protein 1	18092	0.14
chr1_128359251_128359552	0.31	Mcm6	minichromosome maintenance complex component 6	246	0.91
chr9_47531410_47531633	0.31	Cadm1	cell adhesion molecule 1	1148	0.49
chr1_72171187_72171446	0.30	Mreg	melanoregulin	40991	0.1
chr18_65247932_65248083	0.30	Mir122	microRNA 122	854	0.54
chr9_119148405_119148556	0.30	Acaa1b	acetyl-Coenzyme A acyltransferase 1B	1583	0.25
chr2_52858397_52858587	0.30	Fmnl2	formin-like 2	624	0.82
chr7_48881274_48881434	0.30	Gm2788	predicted gene 2788	54	0.74
chr8_64767198_64767355	0.30	Klhl2	kelch-like 2, Mayven	12305	0.16
chr4_135516112_135516333	0.30	Gm25317	predicted gene, 25317	3743	0.16
chr6_87590696_87590858	0.30	Prokr1	prokineticin receptor 1	34	0.97
chr2_157007239_157007486	0.30	Dsn1	DSN1 homolog, MIS12 kinetochore complex component	208	0.9
chr4_135420119_135420277	0.29	Mir700	microRNA 700	3565	0.12
chr1_169919370_169919536	0.29	Ccdc190	coiled-coil domain containing 190	9195	0.17
chr1_79857847_79858438	0.29	Serpine2	serine (or cysteine) peptidase inhibitor, clade E, member 2	493	0.83
chrX_168795419_168795570	0.29	Arhgap6	Rho GTPase activating protein 6	395	0.89
chr13_31559718_31559877	0.29	A530084C06Rik	RIKEN cDNA A530084C06 gene	464	0.73
chr11_106249671_106250177	0.29	Ftsj3	FtsJ RNA methyltransferase homolog 3 (E. coli)	774	0.42
chr2_167570275_167570599	0.29	Gm11476	predicted gene 11476	17123	0.11
chr2_132252667_132252827	0.29	Pcna	proliferating cell nuclear antigen	145	0.85
chr2_167574964_167575153	0.29	Gm11475	predicted gene 11475	16337	0.11
chr4_153957077_153957238	0.28	A430005L14Rik	RIKEN cDNA A430005L14 gene	80	0.95
chr1_93135406_93135557	0.28	Agxt	alanine-glyoxylate aminotransferase	87	0.95
chr12_59219022_59219224	0.28	Fbxo33	F-box protein 33	322	0.86
chr6_29917136_29917315	0.28	Strip2	striatin interacting protein 2	212	0.88
chr3_19895212_19895377	0.28	4632415L05Rik	RIKEN cDNA 4632415L05 gene	312	0.89
chr17_29056624_29056784	0.28	Gm41556	predicted gene, 41556	156	0.9
chr5_140701925_140702124	0.28	Iqce	IQ motif containing E	55	0.97
chr7_143599568_143599932	0.28	Cars	cysteinyl-tRNA synthetase	69	0.82
chr11_5541916_5542088	0.28	Ccdc117	coiled-coil domain containing 117	185	0.92
chr4_129600776_129601168	0.28	Tmem234	transmembrane protein 234	11	0.81
chr12_21112057_21112211	0.28	Asap2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	180	0.96
chr5_8622651_8622802	0.28	Rundc3b	RUN domain containing 3B	226	0.94
chr9_24499400_24499590	0.28	Dpy19l1	dpy-19-like 1 (C. elegans)	2323	0.31
chr10_91082443_91082594	0.28	Apaf1	apoptotic peptidase activating factor 1	89	0.84
chr1_21079589_21079810	0.28	Gm28287	predicted gene 28287	415	0.51
chr7_30535115_30535276	0.27	Arhgap33	Rho GTPase activating protein 33	135	0.85
chr13_55329990_55330168	0.27	Mxd3	Max dimerization protein 3	256	0.85
chr4_133369891_133370073	0.27	Mir5122	microRNA 5122	206	0.57
chr9_21010755_21010906	0.27	Icam1	intercellular adhesion molecule 1	5155	0.08
chr8_84893555_84893706	0.27	Gcdh	glutaryl-Coenzyme A dehydrogenase	155	0.87
chr13_22006021_22006172	0.27	Prss16	protease, serine 16 (thymus)	316	0.68
chr17_85091006_85091157	0.27	Camkmt	calmodulin-lysine N-methyltransferase	475	0.65
chr4_141663419_141663714	0.27	Plekhm2	pleckstrin homology domain containing, family M (with RUN domain) member 2	552	0.67
chr2_181287544_181287702	0.27	Gmeb2	glucocorticoid modulatory element binding protein 2	393	0.73
chr2_114099402_114099798	0.27	Aqr	aquarius	19587	0.16
chr11_49847095_49847246	0.27	Mapk9	mitogen-activated protein kinase 9	277	0.9
chr1_179847829_179847985	0.27	Ahctf1	AT hook containing transcription factor 1	44227	0.13
chr18_60601453_60601636	0.27	Synpo	synaptopodin	1047	0.47
chr2_151996379_151996542	0.27	Slc52a3	solute carrier protein family 52, member 3	51	0.96
chr2_38286777_38287020	0.26	Dennd1a	DENN/MADD domain containing 1A	290	0.86
chr13_95618213_95618364	0.26	F2r	coagulation factor II (thrombin) receptor	199	0.93
chr6_100670825_100671026	0.26	Shq1	SHQ1 homolog (S. cerevisiae)	208	0.92
chr13_21180068_21180231	0.26	Trim27	tripartite motif-containing 27	75	0.96
chr15_75862455_75863017	0.26	Gsdmd	gasdermin D	357	0.74
chr11_21080920_21081322	0.26	Peli1	pellino 1	10170	0.2
chr15_98805374_98805536	0.26	B130046B21Rik	RIKEN cDNA B130046B21 gene	1569	0.19
chr1_133163770_133164045	0.26	Plekha6	pleckstrin homology domain containing, family A member 6	303	0.89
chr12_40596271_40596511	0.26	Dock4	dedicator of cytokinesis 4	150055	0.04
chr18_60848442_60848618	0.26	Tcof1	treacle ribosome biogenesis factor 1	84	0.96
chr17_6316978_6317224	0.26	Dynlt1a	dynein light chain Tctex-type 1A	317	0.82
chr17_53567606_53567787	0.26	Kat2b	K(lysine) acetyltransferase 2B	725	0.62
chr7_100492974_100493189	0.26	Ucp2	uncoupling protein 2 (mitochondrial, proton carrier)	256	0.83
chr13_29945538_29945696	0.26	Gm11365	predicted gene 11365	5334	0.25
chr12_111759014_111759441	0.26	Klc1	kinesin light chain 1	214	0.89
chr2_103565693_103566028	0.26	Abtb2	ankyrin repeat and BTB (POZ) domain containing 2	450	0.83
chr7_64048693_64048852	0.26	Gm45054	predicted gene 45054	7946	0.16
chr11_17953583_17953741	0.26	Etaa1	Ewing tumor-associated antigen 1	213	0.61
chr18_4956286_4956555	0.26	Svil	supervillin	34694	0.22
chr5_110110403_110110732	0.25	Zfp605	zinc finger protein 605	216	0.85
chr4_136177846_136177997	0.25	E2f2	E2F transcription factor 2	2862	0.19
chr18_54953610_54953761	0.25	Zfp608	zinc finger protein 608	3072	0.28
chr1_36535791_36536054	0.25	Ankrd23	ankyrin repeat domain 23	183	0.87
chr4_34730156_34730312	0.25	Cfap206	cilia and flagella associated protein 206	28	0.97
chr11_20831246_20831415	0.25	Lgalsl	lectin, galactoside binding-like	274	0.72
chr4_148140591_148140767	0.25	Mad2l2	MAD2 mitotic arrest deficient-like 2	45	0.95
chr15_98092785_98093187	0.25	Senp1	SUMO1/sentrin specific peptidase 1	99	0.64
chr13_12257493_12257701	0.25	Mtr	5-methyltetrahydrofolate-homocysteine methyltransferase	498	0.74
chr19_45805094_45805257	0.25	Kcnip2	Kv channel-interacting protein 2	1601	0.31
chr11_89999415_89999783	0.25	Pctp	phosphatidylcholine transfer protein	3295	0.3
chr2_84744034_84744230	0.25	Gm19426	predicted gene, 19426	477	0.61
chr3_158036818_158036969	0.25	Lrrc40	leucine rich repeat containing 40	33	0.72
chr7_81706851_81707046	0.25	Homer2	homer scaffolding protein 2	4	0.97
chr17_21753956_21754159	0.25	Zfp229	zinc finger protein 229	18145	0.11
chr11_98294523_98294694	0.25	Gm20644	predicted gene 20644	9226	0.1
chr4_133241348_133241936	0.25	Map3k6	mitogen-activated protein kinase kinase kinase 6	824	0.47
chr19_44742201_44742385	0.25	Gm35610	predicted gene, 35610	940	0.5
chr8_122678212_122678419	0.25	Cbfa2t3	CBFA2/RUNX1 translocation partner 3	140	0.92
chr17_34586879_34587070	0.25	Notch4	notch 4	29	0.91
chr3_129531047_129531198	0.25	Gm35986	predicted gene, 35986	987	0.39
chr13_100744587_100744752	0.25	Mrps36	mitochondrial ribosomal protein S36	10	0.96
chr9_119357444_119357603	0.25	Xylb	xylulokinase homolog (H. influenzae)	46	0.96
chr11_51916701_51916882	0.25	Gm39822	predicted gene, 39822	17825	0.14
chr7_30360114_30360296	0.25	Lrfn3	leucine rich repeat and fibronectin type III domain containing 3	2567	0.1
chr7_128010040_128010379	0.25	Gm19366	predicted gene, 19366	2975	0.09
chr4_120825407_120825586	0.25	Nfyc	nuclear transcription factor-Y gamma	188	0.91
chr5_107437718_107438041	0.24	Btbd8	BTB (POZ) domain containing 8	118	0.93
chr19_44563003_44563199	0.24	Hif1an	hypoxia-inducible factor 1, alpha subunit inhibitor	251	0.88
chr3_59006560_59006721	0.24	Med12l	mediator complex subunit 12-like	153	0.8
chr17_30601575_30601726	0.24	Glo1	glyoxalase 1	705	0.46
chr7_118518801_118518969	0.24	Coq7	demethyl-Q 7	7849	0.15
chr8_44937447_44937668	0.24	Fat1	FAT atypical cadherin 1	2110	0.3
chr8_17664781_17664932	0.24	Csmd1	CUB and Sushi multiple domains 1	129270	0.06
chr10_30200075_30200299	0.24	Cenpw	centromere protein W	305	0.92
chr1_59684305_59684456	0.24	Nop58	NOP58 ribonucleoprotein	591	0.56
chr5_124352244_124352411	0.24	Cdk2ap1	CDK2 (cyclin-dependent kinase 2)-associated protein 1	94	0.95
chr13_117024345_117024496	0.24	Parp8	poly (ADP-ribose) polymerase family, member 8	853	0.64
chr17_26602801_26603141	0.24	Ergic1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	747	0.54
chr1_78657322_78657585	0.24	Acsl3	acyl-CoA synthetase long-chain family member 3	372	0.62
chr16_17210099_17210269	0.24	Rimbp3	RIMS binding protein 3	1581	0.21
chr15_84855689_84855840	0.24	Phf21b	PHD finger protein 21B	13	0.97
chr8_95807155_95807326	0.24	Cnot1	CCR4-NOT transcription complex, subunit 1	141	0.65
chr7_143978352_143978545	0.24	Shank2	SH3 and multiple ankyrin repeat domains 2	23480	0.16
chr4_145246125_145246511	0.23	Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	552	0.79
chr8_12672095_12672260	0.23	4931415C17Rik	RIKEN cDNA 4931415C17 gene	9	0.52
chr15_50361351_50361717	0.23	Gm49198	predicted gene, 49198	74636	0.13
chr13_73733026_73733394	0.23	Slc12a7	solute carrier family 12, member 7	116	0.96
chr6_6210752_6211010	0.23	Slc25a13	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13	6237	0.25
chr6_47920220_47920375	0.23	Zfp212	Zinc finger protein 212	179	0.92
chr10_52690737_52690888	0.23	Slc35f1	solute carrier family 35, member F1	279	0.9
chr19_5038948_5039147	0.23	B4gat1	beta-1,4-glucuronyltransferase 1	140	0.49
chr1_133045746_133045897	0.23	Pik3c2b	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta	154	0.94
chr11_107547459_107547712	0.23	Helz	helicase with zinc finger domain	345	0.7
chr2_70509001_70509542	0.23	Erich2os	glutamate rich 2, opposite strand	72	0.66
chr11_104571330_104571492	0.23	Gm11663	predicted gene 11663	146	0.92
chr11_3408533_3408935	0.23	Limk2	LIM motif-containing protein kinase 2	440	0.75
chr7_101741464_101741615	0.23	Clpb	ClpB caseinolytic peptidase B	22040	0.13
chr4_114909130_114909304	0.23	Foxd2os	forkhead box D2, opposite strand	40	0.83
chr4_143161589_143161992	0.23	Gm13039	predicted gene 13039	4813	0.16
chr14_55671605_55671777	0.23	Nedd8	neural precursor cell expressed, developmentally down-regulated gene 8	182	0.53

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0046439	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.1	0.4	GO:0006597	spermine biosynthetic process(GO:0006597)
0.1	0.4	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.1	0.4	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1	0.3	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1	0.3	GO:0009826	unidimensional cell growth(GO:0009826)
0.1	0.1	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.3	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	0.3	GO:1902990	mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1	0.3	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.1	0.4	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1	0.3	GO:1902263	apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1	0.3	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1	0.3	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.1	0.3	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.1	0.4	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.1	0.4	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.2	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1	0.2	GO:0045297	mating plug formation(GO:0042628) post-mating behavior(GO:0045297)
0.1	0.2	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
0.1	0.2	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.1	0.2	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.1	0.2	GO:1903849	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1	0.2	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1	0.3	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.1	0.4	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.1	0.3	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.1	0.2	GO:2000409	positive regulation of T cell extravasation(GO:2000409)
0.1	0.2	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1	0.3	GO:2001280	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1	0.3	GO:0061113	pancreas morphogenesis(GO:0061113)
0.1	0.1	GO:0090069	regulation of ribosome biogenesis(GO:0090069)
0.1	0.3	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1	0.2	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.1	0.2	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.1	0.2	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1	0.1	GO:0016095	polyprenol catabolic process(GO:0016095)
0.1	0.2	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.1	0.2	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	0.2	GO:0021564	vagus nerve development(GO:0021564)
0.1	0.4	GO:0015871	choline transport(GO:0015871)
0.1	0.2	GO:0042732	D-xylose metabolic process(GO:0042732)
0.1	0.3	GO:1900133	regulation of renin secretion into blood stream(GO:1900133)
0.1	0.4	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.1	0.2	GO:0072076	nephrogenic mesenchyme development(GO:0072076)
0.1	0.2	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1	0.2	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1	0.2	GO:0021586	pons maturation(GO:0021586)
0.1	0.2	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.1	0.2	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.1	0.2	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.1	0.2	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.1	0.2	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.1	0.2	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.1	0.2	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.1	0.2	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.1	0.2	GO:1901421	positive regulation of response to alcohol(GO:1901421)
0.1	0.1	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0	0.2	GO:0007066	female meiosis sister chromatid cohesion(GO:0007066)
0.0	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.2	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:0002432	granuloma formation(GO:0002432)
0.0	0.0	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0	0.2	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.3	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.2	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.1	GO:0042851	L-alanine metabolic process(GO:0042851)
0.0	0.1	GO:2000047	regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.0	0.1	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.0	0.2	GO:0033216	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.0	0.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.2	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.0	0.1	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0	0.1	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.0	0.2	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.2	GO:1990000	amyloid fibril formation(GO:1990000)
0.0	0.1	GO:1904431	positive regulation of t-circle formation(GO:1904431)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.1	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.0	0.2	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	0.0	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	0.4	GO:0039702	viral budding via host ESCRT complex(GO:0039702)
0.0	0.1	GO:0032439	endosome localization(GO:0032439)
0.0	0.2	GO:1903333	negative regulation of protein folding(GO:1903333)
0.0	0.1	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0	0.2	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0	0.9	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.0	0.4	GO:0070202	regulation of establishment of protein localization to chromosome(GO:0070202)
0.0	0.1	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	0.2	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
0.0	0.5	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.0	0.5	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.0	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0	0.2	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0	0.1	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.0	0.3	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0	0.1	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.1	GO:0006210	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.2	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.3	GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0	0.2	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.0	GO:0046137	negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.2	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.1	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.4	GO:0030828	positive regulation of cGMP biosynthetic process(GO:0030828)
0.0	0.1	GO:0071462	cellular response to water stimulus(GO:0071462)
0.0	0.3	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.1	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.0	0.1	GO:2000152	regulation of ubiquitin-specific protease activity(GO:2000152)
0.0	0.2	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0	0.1	GO:0071725	response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0	0.3	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.2	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.0	0.1	GO:1903423	positive regulation of synaptic vesicle recycling(GO:1903423)
0.0	0.1	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.1	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0	0.1	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.0	0.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.0	0.2	GO:0007619	courtship behavior(GO:0007619)
0.0	0.4	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0	0.2	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.1	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.0	0.0	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.0	0.2	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.0	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.0	0.1	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.0	0.1	GO:0048295	positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0	0.1	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.1	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0	0.3	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.1	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.1	GO:1901529	positive regulation of anion channel activity(GO:1901529)
0.0	0.1	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.1	GO:0051136	regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.2	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.2	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.2	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0	0.1	GO:1902570	protein localization to nucleolus(GO:1902570)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.1	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.1	GO:0009169	ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0035630	bone mineralization involved in bone maturation(GO:0035630)
0.0	0.2	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0010481	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0	0.1	GO:0032202	telomere assembly(GO:0032202)
0.0	0.1	GO:0070200	establishment of protein localization to telomere(GO:0070200)
0.0	0.1	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0	0.1	GO:0071033	nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0	0.4	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.1	GO:0045472	response to ether(GO:0045472)
0.0	0.1	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.0	0.1	GO:0072697	protein localization to cell cortex(GO:0072697)
0.0	0.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.1	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.0	0.3	GO:0009208	pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208)
0.0	0.1	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.1	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.0	0.1	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.0	0.2	GO:0032875	regulation of DNA endoreduplication(GO:0032875)
0.0	0.0	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.0	GO:0019064	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.1	GO:0002071	glandular epithelial cell maturation(GO:0002071)
0.0	0.2	GO:0060613	fat pad development(GO:0060613)
0.0	0.1	GO:0042738	exogenous drug catabolic process(GO:0042738)
0.0	0.1	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.0	0.1	GO:0031642	negative regulation of myelination(GO:0031642)
0.0	0.1	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.0	0.3	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.2	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.1	GO:0070666	mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0	0.0	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
0.0	0.2	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.1	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.0	0.1	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.0	0.3	GO:0035337	fatty-acyl-CoA metabolic process(GO:0035337)
0.0	0.1	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0	0.1	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
0.0	0.2	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.2	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0007418	ventral midline development(GO:0007418)
0.0	0.1	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0	0.2	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0	0.2	GO:0070269	pyroptosis(GO:0070269)
0.0	0.2	GO:0070166	enamel mineralization(GO:0070166)
0.0	0.1	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.0	0.1	GO:1900378	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0	0.1	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.2	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.0	0.2	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0051013	microtubule severing(GO:0051013)
0.0	0.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.1	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.0	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.0	GO:0002424	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0	0.1	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
0.0	0.1	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0051799	negative regulation of hair follicle development(GO:0051799)
0.0	0.1	GO:1904177	regulation of adipose tissue development(GO:1904177)
0.0	0.0	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0	0.0	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0	0.1	GO:0033762	response to glucagon(GO:0033762)
0.0	0.1	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.1	GO:0031034	myosin filament assembly(GO:0031034)
0.0	0.1	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
0.0	0.1	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0	0.0	GO:0046061	dATP catabolic process(GO:0046061)
0.0	0.0	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.1	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.0	0.1	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.1	GO:0051031	tRNA transport(GO:0051031)
0.0	0.1	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.1	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282)
0.0	0.0	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.3	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.0	0.1	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.0	0.1	GO:0070932	histone H3 deacetylation(GO:0070932)
0.0	0.1	GO:0016115	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	0.1	GO:1904415	regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.0	0.3	GO:0010669	epithelial structure maintenance(GO:0010669)
0.0	0.1	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.1	GO:1903054	negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.1	GO:0035878	nail development(GO:0035878)
0.0	0.1	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.1	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.2	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:1904526	regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.0	0.1	GO:0035754	B cell chemotaxis(GO:0035754)
0.0	0.1	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.0	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.0	0.0	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.0	0.1	GO:0060283	negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0	0.1	GO:0042761	very long-chain fatty acid biosynthetic process(GO:0042761)
0.0	0.2	GO:0051383	kinetochore organization(GO:0051383)
0.0	0.2	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.1	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.1	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.1	GO:0000338	protein deneddylation(GO:0000338) cullin deneddylation(GO:0010388)
0.0	0.0	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.0	0.0	GO:0035087	siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0	0.0	GO:0019287	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.2	GO:0097237	cellular response to toxic substance(GO:0097237)
0.0	0.0	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.0	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	0.3	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.0	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0	0.0	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)
0.0	0.1	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.0	GO:0010635	regulation of mitochondrial fusion(GO:0010635)
0.0	0.1	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.0	0.1	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.0	0.0	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.3	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.1	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.2	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.0	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.0	0.0	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.0	0.1	GO:0006056	cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
0.0	0.0	GO:0034086	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.0	0.0	GO:1904222	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.0	0.0	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.0	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.0	GO:0051081	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0	0.2	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.0	GO:0060279	positive regulation of ovulation(GO:0060279)
0.0	0.1	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0	0.1	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.0	GO:0072205	metanephric collecting duct development(GO:0072205)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.1	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.0	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.0	0.1	GO:0001927	exocyst assembly(GO:0001927)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.0	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.0	0.0	GO:0046618	drug export(GO:0046618)
0.0	0.1	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.1	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	0.0	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.2	GO:0061462	protein localization to lysosome(GO:0061462)
0.0	0.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0043173	nucleotide salvage(GO:0043173)
0.0	0.3	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.0	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.0	0.0	GO:0021540	corpus callosum morphogenesis(GO:0021540)
0.0	0.1	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.0	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.2	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.0	0.0	GO:0097501	stress response to metal ion(GO:0097501)
0.0	0.0	GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0	0.1	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0	0.4	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.0	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.0	0.0	GO:0017085	response to insecticide(GO:0017085)
0.0	0.0	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0	0.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.0	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.0	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.0	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation(GO:0003198)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0046098	guanine metabolic process(GO:0046098)
0.0	0.0	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.5	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.1	GO:0033750	ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.0	0.0	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.0	0.2	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.0	GO:0051661	maintenance of centrosome location(GO:0051661)
0.0	0.0	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.0	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0	0.2	GO:0071451	cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
0.0	0.1	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.0	0.0	GO:0071351	response to interleukin-18(GO:0070673) cellular response to interleukin-18(GO:0071351)
0.0	0.2	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.0	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.0	0.0	GO:0019896	axonal transport of mitochondrion(GO:0019896)
0.0	0.0	GO:0061622	glycolytic process through glucose-1-phosphate(GO:0061622)
0.0	0.2	GO:0048246	macrophage chemotaxis(GO:0048246)
0.0	0.0	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.0	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.0	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.0	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.0	0.0	GO:1902592	viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.0	0.0	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.0	GO:0097694	establishment of RNA localization to telomere(GO:0097694)
0.0	0.1	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.1	GO:0042635	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0	0.0	GO:0009202	deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.0	0.2	GO:0010259	multicellular organism aging(GO:0010259)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.0	0.2	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.0	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.0	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.0	GO:0090399	replicative senescence(GO:0090399)
0.0	0.0	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.1	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.0	0.1	GO:0090220	chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0031084	BLOC-2 complex(GO:0031084)
0.1	0.4	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.1	0.3	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.1	0.2	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.1	0.3	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	0.4	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.1	0.2	GO:0070939	Dsl1p complex(GO:0070939)
0.1	0.4	GO:0000801	central element(GO:0000801)
0.1	0.3	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.1	0.2	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.1	0.2	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	0.2	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1	0.2	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.1	0.5	GO:0000815	ESCRT III complex(GO:0000815)
0.1	0.5	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.2	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.2	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.2	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.1	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0	0.2	GO:0030689	Noc complex(GO:0030689)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	0.1	GO:0043293	apoptosome(GO:0043293)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.2	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.0	0.2	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.2	GO:0000805	X chromosome(GO:0000805)
0.0	0.2	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.3	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.3	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.2	GO:0044214	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0	0.3	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.2	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.3	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.3	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	0.3	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.1	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.0	0.2	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.1	GO:0044308	axonal spine(GO:0044308)
0.0	0.2	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.2	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0036449	microtubule minus-end(GO:0036449)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.1	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.2	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.1	GO:0000235	astral microtubule(GO:0000235)
0.0	0.1	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.0	0.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0071439	clathrin complex(GO:0071439)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.1	GO:0000938	GARP complex(GO:0000938)
0.0	0.3	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.0	GO:0042585	germinal vesicle(GO:0042585)
0.0	0.1	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.6	GO:0030894	replisome(GO:0030894)
0.0	0.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.2	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.2	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.2	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	1.1	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.3	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.4	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.2	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	0.2	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.2	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.2	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0001651	dense fibrillar component(GO:0001651)
0.0	0.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.3	GO:0043196	varicosity(GO:0043196)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.1	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.0	0.1	GO:0038037	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.3	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.2	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.3	GO:0030904	retromer complex(GO:0030904)
0.0	0.2	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.0	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.2	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.0	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.0	0.5	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	0.2	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.0	0.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.0	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.0	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:0031502	dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0	0.0	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	0.1	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.1	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.0	GO:0097443	sorting endosome(GO:0097443)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.3	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.0	GO:0097543	ciliary inversin compartment(GO:0097543)
0.0	0.0	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.1	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.1	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.2	GO:0043596	nuclear replication fork(GO:0043596)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.1	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.1	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.2	GO:0097440	apical dendrite(GO:0097440)
0.0	0.0	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.0	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.1	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.0	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0030686	90S preribosome(GO:0030686)
0.0	0.0	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.0	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.1	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.1	GO:0002177	manchette(GO:0002177)
0.0	0.2	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1	0.1	GO:0016662	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662)
0.1	0.4	GO:0019808	polyamine binding(GO:0019808)
0.1	0.3	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.3	GO:0043398	HLH domain binding(GO:0043398)
0.1	0.5	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	0.1	GO:0008193	tRNA guanylyltransferase activity(GO:0008193)
0.1	0.3	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.3	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	0.2	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	0.3	GO:0070878	primary miRNA binding(GO:0070878)
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.2	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	0.4	GO:0001727	lipid kinase activity(GO:0001727)
0.1	0.2	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	0.3	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.2	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1	0.5	GO:0016004	phospholipase activator activity(GO:0016004)
0.1	0.2	GO:1990715	mRNA CDS binding(GO:1990715)
0.1	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.3	GO:0032405	MutLalpha complex binding(GO:0032405)
0.1	0.2	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1	0.2	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.0	0.2	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0016649	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0	0.1	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0089720	caspase binding(GO:0089720)
0.0	0.1	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.2	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.1	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.1	GO:0004793	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0	0.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.2	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.3	GO:0016885	ligase activity, forming carbon-carbon bonds(GO:0016885)
0.0	0.2	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.1	GO:1990188	euchromatin binding(GO:1990188)
0.0	0.3	GO:0046790	virion binding(GO:0046790)
0.0	0.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.2	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.2	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.4	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.3	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.1	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.1	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.0	0.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.2	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0	0.1	GO:0047751	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0	0.5	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.2	GO:0008410	CoA-transferase activity(GO:0008410)
0.0	0.3	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.3	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0	0.2	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.5	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.3	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.3	GO:0031432	titin binding(GO:0031432)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.3	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.2	GO:1990446	U1 snRNP binding(GO:1990446)
0.0	0.2	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.2	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.1	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.3	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.3	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.2	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.1	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.2	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.2	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.2	GO:0018644	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0	0.2	GO:0033677	DNA/RNA helicase activity(GO:0033677)
0.0	0.1	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.0	GO:0015087	cobalt ion transmembrane transporter activity(GO:0015087)
0.0	0.1	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.1	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	0.2	GO:0045545	syndecan binding(GO:0045545)
0.0	0.3	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.4	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.2	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.0	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.4	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.2	GO:0031386	protein tag(GO:0031386)
0.0	0.1	GO:0102345	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.1	GO:0035514	DNA demethylase activity(GO:0035514)
0.0	0.4	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.3	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.0	0.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.3	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.4	GO:0008483	transaminase activity(GO:0008483)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0016015	morphogen activity(GO:0016015)
0.0	0.2	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.2	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.2	GO:0051765	inositol tetrakisphosphate kinase activity(GO:0051765)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.3	GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
0.0	0.1	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.0	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.1	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.1	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.2	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.0	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.0	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.0	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.0	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.0	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0	0.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.0	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.1	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0	0.2	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.0	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0	0.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.5	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.0	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.0	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.0	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.0	0.0	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.1	GO:0004945	angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.0	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0071253	connexin binding(GO:0071253)
0.0	0.1	GO:0032027	myosin light chain binding(GO:0032027)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.0	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.0	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.0	0.3	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.0	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0	0.0	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.0	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.1	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
0.0	0.1	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.0	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.2	GO:0051183	vitamin transporter activity(GO:0051183)
0.0	0.2	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0	0.1	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.4	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:1990939	ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.0	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.2	PID IL3 PATHWAY	IL3-mediated signaling events
0.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.5	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.6	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.6	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.5	PID BARD1 PATHWAY	BARD1 signaling events
0.9	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.5	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.2	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.2	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.3	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.4	PID FOXO PATHWAY	FoxO family signaling
0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.1	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.2	PID ARF 3PATHWAY	Arf1 pathway
0.1	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	PID AURORA A PATHWAY	Aurora A signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.6	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.2	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.9	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.8	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.4	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.3	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.4	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.6	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.8	REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.4	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.2	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.1	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.5	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.1	REACTOME MITOTIC G2 G2 M PHASES	Genes involved in Mitotic G2-G2/M phases
0.3	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.2	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade

Results for E2f1

Z-value: 1.89

Motif logo

Transcription factors associated with E2f1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the E2f1 motif across conditions

Conditions sorted by the z-value of the E2f1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: