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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for E2f2_E2f5

Z-value: 1.86

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Transcription factors associated with E2f2_E2f5

Gene Symbol Gene ID Gene Info
ENSMUSG00000018983.9 E2f2
ENSMUSG00000027552.8 E2f5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

GenePromoterDistanceAssociation probabilityPearson corr. coef.P-valuePlot
E2f2chr4_136177846_13617799728620.1947440.962.8e-03Click!
E2f2chr4_136173497_13617366711880.3908760.911.2e-02Click!
E2f2chr4_136174892_13617504625750.2068010.891.6e-02Click!
E2f2chr4_136174341_13617451120320.2446230.815.3e-02Click!
E2f2chr4_136171513_1361717017870.5528500.786.5e-02Click!
E2f5chr3_14578527_14578688340.9669940.936.8e-03Click!
E2f5chr3_14578695_145793033280.8450970.853.0e-02Click!
E2f5chr3_14579339_145795397680.561548-0.777.5e-02Click!
E2f5chr3_14579545_145797249630.468221-0.384.6e-01Click!
E2f5chr3_14579749_1457990011530.399227-0.335.3e-01Click!

Activity of the E2f2_E2f5 motif across conditions

Conditions sorted by the z-value of the E2f2_E2f5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_98146443_98146601 0.99 Omp
olfactory marker protein
1020
0.47
chr2_156447550_156447712 0.94 Gm14225
predicted gene 14225
23
0.96
chr5_148674254_148674405 0.79 Gm36186
predicted gene, 36186
37137
0.13
chr18_46341760_46341934 0.67 4930415P13Rik
RIKEN cDNA 4930415P13 gene
1418
0.34
chr12_99269518_99269669 0.64 Foxn3
forkhead box N3
21684
0.14
chr5_23413691_23413875 0.58 Gm42509
predicted gene 42509
17680
0.11
chr5_121838276_121838548 0.57 Sh2b3
SH2B adaptor protein 3
766
0.47
chr13_111796213_111796385 0.57 Map3k1
mitogen-activated protein kinase kinase kinase 1
12016
0.14
chr19_7217620_7217775 0.56 Cox8a
cytochrome c oxidase subunit 8A
81
0.95
chr8_33913458_33913624 0.54 Rbpms
RNA binding protein gene with multiple splicing
15735
0.16
chr5_102775781_102775953 0.52 Arhgap24
Rho GTPase activating protein 24
7096
0.31
chr5_139835784_139835950 0.52 Psmg3
proteasome (prosome, macropain) assembly chaperone 3
8982
0.13
chr2_173162438_173162602 0.49 Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic
9438
0.17
chr2_22623304_22623471 0.49 Gad2
glutamic acid decarboxylase 2
83
0.96
chr15_79883594_79883768 0.49 AC113595.1
novel transcript, antisense to Apobec3
5851
0.11
chr15_55090420_55090606 0.49 Dscc1
DNA replication and sister chromatid cohesion 1
22
0.97
chr8_49012977_49013144 0.49 Gm45830
predicted gene 45830
31220
0.18
chr11_62487650_62487823 0.48 Gm12278
predicted gene 12278
4939
0.13
chr14_47188793_47188954 0.48 Gch1
GTP cyclohydrolase 1
540
0.62
chr3_96571864_96572239 0.48 Gm16253
predicted gene 16253
4933
0.08
chr4_56961559_56961774 0.48 Tmem245
transmembrane protein 245
14229
0.15
chr15_79683713_79683872 0.47 Gm49520
predicted gene, 49520
2470
0.13
chr7_30360114_30360296 0.46 Lrfn3
leucine rich repeat and fibronectin type III domain containing 3
2567
0.1
chr7_132574591_132574901 0.46 Oat
ornithine aminotransferase
972
0.5
chr6_117758642_117759021 0.45 1700030F04Rik
RIKEN cDNA 1700030F04 gene
7062
0.19
chr11_112779929_112780096 0.45 BC006965
cDNA sequence BC006965
1964
0.28
chr8_12709584_12709755 0.45 Gm15348
predicted gene 15348
9458
0.15
chr7_68915875_68916026 0.44 Gm34664
predicted gene, 34664
56
0.98
chr15_78174003_78174159 0.44 Ift27
intraflagellar transport 27
26
0.85
chr8_70904582_70904751 0.43 Map1s
microtubule-associated protein 1S
1266
0.23
chr19_41661137_41661296 0.43 Slit1
slit guidance ligand 1
52686
0.12
chr9_62358912_62359088 0.43 Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
7938
0.21
chr19_38930814_38930975 0.42 Hells
helicase, lymphoid specific
21
0.98
chr6_21949358_21949518 0.42 Ing3
inhibitor of growth family, member 3
133
0.97
chr11_79647043_79647213 0.41 Gm24887
predicted gene, 24887
8000
0.11
chr7_28796738_28796906 0.41 Rinl
Ras and Rab interactor-like
116
0.91
chr13_23761471_23761669 0.41 H4c1
H4 clustered histone 1
340
0.53
chr1_36535791_36536054 0.41 Ankrd23
ankyrin repeat domain 23
183
0.87
chr9_77707832_77708042 0.41 Gm47789
predicted gene, 47789
55
0.97
chr2_129800360_129800704 0.40 Stk35
serine/threonine kinase 35
15
0.98
chr2_181288071_181288225 0.39 Gmeb2
glucocorticoid modulatory element binding protein 2
113
0.93
chr11_7215786_7215938 0.39 Igfbp3
insulin-like growth factor binding protein 3
1939
0.32
chr11_119314655_119314806 0.39 Card14
caspase recruitment domain family, member 14
57
0.96
chr6_4747270_4747444 0.39 Peg10
paternally expressed 10
49
0.63
chr17_35736688_35736839 0.39 Gm20443
predicted gene 20443
3043
0.11
chr19_3208419_3208579 0.38 Gm50432
predicted gene, 50432
2706
0.16
chr18_35887757_35887908 0.38 Gm36315
predicted gene, 36315
2505
0.16
chr1_182143366_182143524 0.38 Srp9
signal recognition particle 9
12746
0.15
chr12_84064755_84064929 0.38 Acot5
acyl-CoA thioesterase 5
4483
0.1
chr14_26006324_26006475 0.37 Gm2260
predicted gene 2260
10032
0.12
chr14_26145943_26146094 0.37 Gm2274
predicted gene 2274
10018
0.12
chr14_26285592_26285743 0.37 Gm18578
predicted gene, 18578
17038
0.12
chr4_138972772_138972945 0.37 Tmco4
transmembrane and coiled-coil domains 4
30
0.97
chr11_113619444_113619605 0.36 Sstr2
somatostatin receptor 2
48
0.97
chr12_69228128_69228315 0.36 Pole2
polymerase (DNA directed), epsilon 2 (p59 subunit)
26
0.78
chr4_150087496_150087672 0.36 Gpr157
G protein-coupled receptor 157
219
0.88
chr12_57230408_57230581 0.36 Mipol1
mirror-image polydactyly 1
3
0.56
chr15_89210193_89210346 0.36 Ppp6r2
protein phosphatase 6, regulatory subunit 2
1284
0.29
chr7_110121546_110121775 0.35 Wee1
WEE 1 homolog 1 (S. pombe)
386
0.76
chr13_98352948_98353139 0.35 Foxd1
forkhead box D1
1199
0.4
chr1_51852458_51852609 0.35 Myo1b
myosin IB
1427
0.36
chr1_38130022_38130190 0.35 Rev1
REV1, DNA directed polymerase
305
0.87
chr1_191641728_191641952 0.35 Gm37349
predicted gene, 37349
44193
0.11
chr11_31841101_31841288 0.35 Gm12107
predicted gene 12107
8534
0.19
chr7_141436148_141436439 0.34 Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
896
0.28
chr11_98907623_98907912 0.34 Cdc6
cell division cycle 6
34
0.96
chr4_115497333_115497797 0.34 Cyp4a14
cytochrome P450, family 4, subfamily a, polypeptide 14
1423
0.29
chr14_55822818_55822969 0.34 Nfatc4
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4
251
0.83
chr5_142929156_142929325 0.34 Actb
actin, beta
22486
0.13
chr1_39535294_39535562 0.33 Cnot11
CCR4-NOT transcription complex, subunit 11
374
0.78
chr12_112644432_112644593 0.33 Siva1
SIVA1, apoptosis-inducing factor
167
0.91
chr10_128923068_128923230 0.33 Bloc1s1
biogenesis of lysosomal organelles complex-1, subunit 1
123
0.66
chr16_85801512_85801670 0.33 Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
110
0.97
chr8_114535625_114535816 0.33 Gm16116
predicted gene 16116
59180
0.12
chr4_32615201_32615368 0.33 Casp8ap2
caspase 8 associated protein 2
167
0.93
chr10_53629362_53629531 0.33 Mcm9
minichromosome maintenance 9 homologous recombination repair factor
513
0.69
chr4_19992397_19992575 0.33 4930480G23Rik
RIKEN cDNA 4930480G23 gene
13087
0.19
chr18_75234415_75234580 0.32 Gm8807
predicted gene 8807
51683
0.12
chr7_127477693_127477849 0.32 Fbrs
fibrosin
1428
0.16
chr9_67633131_67633282 0.32 Gm47110
predicted gene, 47110
66975
0.09
chr2_167260546_167260697 0.32 Ptgis
prostaglandin I2 (prostacyclin) synthase
20017
0.13
chr10_127342400_127342556 0.32 Gli1
GLI-Kruppel family member GLI1
504
0.57
chr17_26114147_26114341 0.32 Tmem8
transmembrane protein 8
901
0.34
chr7_113207183_113207355 0.31 Arntl
aryl hydrocarbon receptor nuclear translocator-like
196
0.95
chr9_43742856_43743217 0.31 Nectin1
nectin cell adhesion molecule 1
948
0.41
chr12_85785468_85785654 0.31 Flvcr2
feline leukemia virus subgroup C cellular receptor 2
10731
0.15
chr3_36475062_36475233 0.31 Mir7009
microRNA 7009
377
0.48
chr10_71347555_71347729 0.30 Ipmk
inositol polyphosphate multikinase
121
0.94
chr5_136135624_136135808 0.30 Lrwd1
leucine-rich repeats and WD repeat domain containing 1
281
0.58
chr8_25602056_25602234 0.30 Nsd3
nuclear receptor binding SET domain protein 3
139
0.91
chr15_73512893_73513074 0.30 Dennd3
DENN/MADD domain containing 3
311
0.89
chr11_101376283_101376946 0.30 G6pc
glucose-6-phosphatase, catalytic
9053
0.06
chr12_85473320_85473671 0.30 Fos
FBJ osteosarcoma oncogene
395
0.83
chr2_29035019_29035395 0.29 Cfap77
cilia and flagella associated protein 77
4153
0.2
chr2_34530230_34530406 0.29 Gm13408
predicted gene 13408
34681
0.16
chr5_99233257_99233431 0.29 Rasgef1b
RasGEF domain family, member 1B
722
0.73
chr5_23251952_23252119 0.29 Gm28022
predicted gene, 28022
27876
0.16
chr4_148144119_148144275 0.29 Mad2l2
MAD2 mitotic arrest deficient-like 2
593
0.55
chr13_21263739_21263906 0.28 Gpx5
glutathione peroxidase 5
28909
0.1
chr13_47105847_47106030 0.28 Dek
DEK oncogene (DNA binding)
108
0.84
chr7_102513169_102513356 0.28 Gm8556
predicted gene 8556
7747
0.07
chr14_75776661_75776851 0.28 Slc25a30
solute carrier family 25, member 30
4428
0.18
chr15_89378320_89378514 0.28 Odf3b
outer dense fiber of sperm tails 3B
191
0.83
chr7_19003930_19004083 0.28 Irf2bp1
interferon regulatory factor 2 binding protein 1
38
0.93
chr4_136144637_136144812 0.28 Id3
inhibitor of DNA binding 3
250
0.89
chr4_106910825_106910982 0.28 Ssbp3
single-stranded DNA binding protein 3
202
0.95
chr5_31093528_31093698 0.28 Slc30a3
solute carrier family 30 (zinc transporter), member 3
2
0.93
chr19_55315246_55315409 0.28 Zdhhc6
zinc finger, DHHC domain containing 6
661
0.54
chr2_156457486_156457755 0.28 Gm14224
predicted gene 14224
1969
0.21
chr4_117279354_117279512 0.28 Rnf220
ring finger protein 220
5650
0.12
chr9_66154137_66154300 0.28 Dapk2
death-associated protein kinase 2
4005
0.21
chr8_70798408_70798701 0.27 Mir7240
microRNA 7240
419
0.6
chr17_65884967_65885131 0.27 Ralbp1
ralA binding protein 1
95
0.87
chr13_59769326_59769477 0.27 Isca1
iron-sulfur cluster assembly 1
76
0.51
chr5_65698209_65698394 0.27 Pds5a
PDS5 cohesin associated factor A
28
0.96
chr19_47348741_47348901 0.27 Sh3pxd2a
SH3 and PX domains 2A
34070
0.15
chr17_80096445_80096646 0.27 Gm23125
predicted gene, 23125
8392
0.15
chr3_121885017_121885175 0.27 Gm42593
predicted gene 42593
22254
0.15
chr7_127260691_127261039 0.27 Dctpp1
dCTP pyrophosphatase 1
156
0.87
chr17_29094634_29094798 0.27 1700023B13Rik
RIKEN cDNA 1700023B13 gene
255
0.77
chrX_101386546_101386756 0.27 Gjb1
gap junction protein, beta 1
2915
0.19
chr11_26593152_26593346 0.26 Gm6899
predicted gene 6899
8
0.85
chr13_60735844_60736400 0.26 Dapk1
death associated protein kinase 1
17874
0.15
chr2_119594156_119594317 0.26 Oip5os1
Opa interacting protein 5, opposite strand 1
61
0.95
chr18_76378806_76378977 0.26 Gm50360
predicted gene, 50360
57067
0.14
chr9_37250045_37250299 0.26 Gm10177
predicted gene 10177
2750
0.13
chr9_108913748_108913914 0.26 Tmem89
transmembrane protein 89
788
0.4
chr4_123587519_123587873 0.26 Macf1
microtubule-actin crosslinking factor 1
14636
0.16
chr5_8998054_8998225 0.26 Crot
carnitine O-octanoyltransferase
815
0.35
chr3_52401175_52401340 0.26 Gm38098
predicted gene, 38098
24151
0.2
chr14_73325714_73325873 0.26 Rb1
RB transcriptional corepressor 1
29
0.98
chr1_10038112_10038275 0.26 Cspp1
centrosome and spindle pole associated protein 1
24
0.49
chr11_57983626_57984029 0.26 Gm12249
predicted gene 12249
10693
0.15
chr18_20946424_20946594 0.26 Rnf125
ring finger protein 125
1884
0.37
chr10_75411837_75412000 0.26 Upb1
ureidopropionase, beta
1875
0.32
chr4_97775109_97775447 0.26 Nfia
nuclear factor I/A
2330
0.28
chr4_119338935_119339105 0.26 Ldha-ps2
lactate dehydrogenase A, pseudogene 2
3575
0.13
chr13_23533566_23533905 0.25 H2ac10
H2A clustered histone 10
171
0.69
chr7_84152712_84152872 0.25 Gm26708
predicted gene, 26708
434
0.66
chr11_8456578_8456775 0.25 Tns3
tensin 3
11999
0.28
chr17_24360969_24361287 0.25 Gm25618
predicted gene, 25618
1416
0.24
chr19_55851785_55852196 0.25 Ppnr
per-pentamer repeat gene
10318
0.25
chr13_41240987_41241148 0.25 Gm32063
predicted gene, 32063
4722
0.13
chr5_138171911_138172068 0.25 Ap4m1
adaptor-related protein complex AP-4, mu 1
13
0.66
chr13_97439501_97439676 0.25 Lncenc1
long non-coding RNA, embryonic stem cells expressed 1
4618
0.2
chr7_48881274_48881434 0.25 Gm2788
predicted gene 2788
54
0.74
chr11_3124565_3124716 0.25 Pisd-ps1
phosphatidylserine decarboxylase, pseudogene 1
1264
0.37
chrX_134757024_134757175 0.25 Armcx3
armadillo repeat containing, X-linked 3
452
0.46
chr9_22071373_22071540 0.25 Zfp653
zinc finger protein 653
80
0.59
chr8_104007719_104007879 0.24 Gm8748
predicted gene 8748
63350
0.1
chr9_36767746_36767915 0.24 Gm26787
predicted gene, 26787
57
0.62
chr10_75475521_75475953 0.24 Gm48158
predicted gene, 48158
7655
0.13
chr17_26115707_26115872 0.24 Tmem8
transmembrane protein 8
842
0.37
chr7_141327534_141327875 0.24 Deaf1
DEAF1, transcription factor
14
0.5
chr17_34632326_34632509 0.24 Prrt1
proline-rich transmembrane protein 1
1013
0.22
chr9_100643293_100643491 0.24 Stag1
stromal antigen 1
56
0.97
chr16_91045477_91045695 0.24 4931406G06Rik
RIKEN cDNA 4931406G06 gene
930
0.33
chr1_190175489_190175675 0.24 Prox1
prospero homeobox 1
4868
0.2
chr4_44016840_44017006 0.24 Clta
clathrin, light polypeptide (Lca)
4237
0.17
chr6_21850864_21851024 0.24 Tspan12
tetraspanin 12
884
0.5
chr2_167574964_167575153 0.24 Gm11475
predicted gene 11475
16337
0.11
chr12_82914756_82914931 0.24 1700085C21Rik
RIKEN cDNA 1700085C21 gene
24312
0.21
chr2_157204467_157204627 0.24 Rbl1
RB transcriptional corepressor like 1
13
0.97
chr11_98770256_98770457 0.24 Nr1d1
nuclear receptor subfamily 1, group D, member 1
70
0.94
chr4_136116896_136117047 0.24 Gm26001
predicted gene, 26001
20525
0.12
chr17_23564159_23564327 0.24 Zfp213
zinc finger protein 213
5
0.94
chr3_132917460_132917629 0.23 Npnt
nephronectin
11185
0.16
chr19_57404259_57404416 0.23 Gm50271
predicted gene, 50271
19157
0.15
chr13_112067503_112067855 0.23 Gm15323
predicted gene 15323
62177
0.1
chr11_74832597_74832764 0.23 Mnt
max binding protein
1760
0.25
chr2_158154122_158154310 0.23 Tgm2
transglutaminase 2, C polypeptide
7780
0.16
chr8_115705724_115706077 0.23 Gm15655
predicted gene 15655
822
0.53
chr17_7284590_7284752 0.23 Rps6ka2
ribosomal protein S6 kinase, polypeptide 2
24035
0.14
chr14_61046171_61046349 0.23 Tnfrsf19
tumor necrosis factor receptor superfamily, member 19
209
0.95
chr3_57510454_57510634 0.23 Gm16016
predicted gene 16016
17688
0.18
chr3_127552939_127553105 0.23 Larp7
La ribonucleoprotein domain family, member 7
175
0.73
chr11_99265900_99266173 0.23 Krt24
keratin 24
19226
0.1
chr11_53299774_53299939 0.23 Hspa4
heat shock protein 4
555
0.71
chr10_20313109_20313327 0.23 Bclaf1
BCL2-associated transcription factor 1
681
0.44
chr8_14246635_14246869 0.23 Gm26184
predicted gene, 26184
26559
0.19
chr7_101821639_101821825 0.23 Phox2a
paired-like homeobox 2a
986
0.33
chr1_181475926_181476204 0.23 Ccdc121
coiled-coil domain containing 121
35386
0.14
chr4_155560766_155560966 0.23 Nadk
NAD kinase
1512
0.26
chr1_121297951_121298102 0.23 Gm38283
predicted gene, 38283
2805
0.24
chr11_9011065_9011245 0.23 Hus1
HUS1 checkpoint clamp component
5
0.98
chr8_41173404_41173555 0.23 Mtus1
mitochondrial tumor suppressor 1
39753
0.13
chr2_126566874_126567095 0.23 Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
2224
0.3
chr14_54417307_54417458 0.22 Slc7a7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
297
0.79
chr6_47191400_47191564 0.22 Cntnap2
contactin associated protein-like 2
52905
0.16
chr11_109473897_109474065 0.22 Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
383
0.59
chr2_126152340_126152692 0.22 Dtwd1
DTW domain containing 1
375
0.59
chr19_3669127_3669720 0.22 Lrp5
low density lipoprotein receptor-related protein 5
17133
0.12
chr4_34613649_34613810 0.22 Orc3
origin recognition complex, subunit 3
1164
0.36
chr16_18248703_18248876 0.22 Ranbp1
RAN binding protein 1
57
0.51
chr18_77714097_77714328 0.22 4930465K10Rik
RIKEN cDNA 4930465K10 gene
2
0.75
chr7_19495565_19495804 0.22 Exoc3l2
exocyst complex component 3-like 2
6628
0.08
chr2_168735267_168735535 0.22 Atp9a
ATPase, class II, type 9A
1062
0.52
chr11_97745116_97745280 0.22 Mir8102
microRNA 8102
301
0.57
chr3_24333217_24333384 0.22 Gm7536
predicted gene 7536
232
0.97
chr11_116808351_116808519 0.22 Mxra7
matrix-remodelling associated 7
19568
0.1

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of E2f2_E2f5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.4 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.9 GO:0097501 stress response to metal ion(GO:0097501)
0.1 0.6 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.3 GO:0060137 maternal process involved in parturition(GO:0060137)
0.1 0.4 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.2 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.3 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.2 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1 0.3 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.2 GO:0048320 axial mesoderm formation(GO:0048320)
0.1 0.3 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 0.2 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.2 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.2 GO:0030242 pexophagy(GO:0030242)
0.1 0.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.2 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.2 GO:0032789 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.1 0.2 GO:0021558 trochlear nerve development(GO:0021558)
0.1 0.2 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.1 0.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 1.0 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.4 GO:0060897 neural plate regionalization(GO:0060897)
0.1 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.1 0.1 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1 0.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.1 GO:0035983 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.1 0.2 GO:0007418 ventral midline development(GO:0007418)
0.1 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.3 GO:0051775 response to redox state(GO:0051775)
0.1 0.2 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.1 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.2 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 0.2 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 0.3 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.4 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.0 0.1 GO:0018992 germ-line sex determination(GO:0018992)
0.0 0.1 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.2 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.2 GO:0033762 response to glucagon(GO:0033762)
0.0 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0060066 oviduct development(GO:0060066)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.4 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.0 0.2 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 0.0 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.0 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0000820 regulation of glutamine family amino acid metabolic process(GO:0000820)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.5 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031)
0.0 0.1 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.0 GO:0007403 glial cell fate determination(GO:0007403)
0.0 0.2 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.1 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.3 GO:0030432 peristalsis(GO:0030432)
0.0 0.1 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.3 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 0.2 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.2 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.1 GO:0021586 pons maturation(GO:0021586)
0.0 0.2 GO:1904415 regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.2 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.1 GO:0010159 specification of organ position(GO:0010159)
0.0 0.1 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0009115 xanthine catabolic process(GO:0009115)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0015744 succinate transport(GO:0015744)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.3 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.1 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.3 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0045472 response to ether(GO:0045472)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.0 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.2 GO:0002934 desmosome organization(GO:0002934)
0.0 0.0 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0 0.1 GO:0060264 regulation of respiratory burst involved in inflammatory response(GO:0060264)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.0 GO:1902065 response to L-glutamate(GO:1902065)
0.0 0.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.1 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.1 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.0 0.0 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0061623 galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0061156 pulmonary artery morphogenesis(GO:0061156)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.0 GO:0003166 bundle of His development(GO:0003166)
0.0 0.1 GO:0071888 macrophage apoptotic process(GO:0071888) regulation of macrophage apoptotic process(GO:2000109)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.0 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 0.6 GO:0071398 cellular response to fatty acid(GO:0071398)
0.0 0.1 GO:0001842 neural fold formation(GO:0001842)
0.0 0.1 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.1 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0006553 lysine metabolic process(GO:0006553)
0.0 0.0 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0 0.2 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.0 0.1 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.2 GO:0097237 cellular response to toxic substance(GO:0097237)
0.0 0.0 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:1903242 regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.0 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.0 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
0.0 0.0 GO:0072282 metanephric nephron tubule morphogenesis(GO:0072282)
0.0 0.1 GO:0015888 thiamine transport(GO:0015888)
0.0 0.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.0 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.1 GO:1903802 L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.0 0.1 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.0 0.1 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.0 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.1 GO:1905065 regulation of vascular smooth muscle cell differentiation(GO:1905063) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.0 0.1 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.0 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.0 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441)
0.0 0.4 GO:0051875 pigment granule localization(GO:0051875)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.0 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.1 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.0 0.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0046070 dGTP metabolic process(GO:0046070)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.0 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.1 GO:1903660 complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.0 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.0 GO:0060268 negative regulation of respiratory burst(GO:0060268)
0.0 0.0 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.0 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.0 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.0 GO:1904683 regulation of metalloendopeptidase activity(GO:1904683) negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0 0.0 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.0 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.0 GO:0061144 alveolar secondary septum development(GO:0061144)
0.0 0.0 GO:0009080 alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.0 GO:0032348 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0 0.1 GO:1901317 regulation of sperm motility(GO:1901317)
0.0 0.0 GO:0060948 cardiac vascular smooth muscle cell development(GO:0060948)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.0 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0 0.1 GO:2000002 negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.2 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.0 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:1901679 nucleotide transmembrane transport(GO:1901679)
0.0 0.0 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.0 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.0 0.0 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.1 GO:2000794 regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.2 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.0 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.2 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.1 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.0 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.0 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0 0.1 GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.0 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.0 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.0 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.0 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.0 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.1 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.0 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.0 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 0.0 GO:1990791 dorsal root ganglion development(GO:1990791)
0.0 0.4 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.0 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.0 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.0 GO:0046146 tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.0 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.0 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:0071548 response to dexamethasone(GO:0071548) cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.0 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:0043312 neutrophil degranulation(GO:0043312)
0.0 0.1 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0044362 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.0 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.0 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.0 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.1 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.0 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.0 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.0 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.0 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.0 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.0 GO:0021636 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637)
0.0 0.1 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 0.1 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.1 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.0 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0014857 regulation of skeletal muscle satellite cell proliferation(GO:0014842) regulation of skeletal muscle cell proliferation(GO:0014857)
0.0 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.0 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0 0.0 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.0 GO:0051795 regulation of catagen(GO:0051794) positive regulation of catagen(GO:0051795)
0.0 0.0 GO:0019042 viral latency(GO:0019042)
0.0 0.2 GO:0060074 synapse maturation(GO:0060074)
0.0 0.1 GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872)
0.0 0.0 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.0 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.0 GO:0010288 response to lead ion(GO:0010288)
0.0 0.0 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.1 GO:0001553 luteinization(GO:0001553)
0.0 0.0 GO:0048382 mesendoderm development(GO:0048382)
0.0 0.1 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.1 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.0 0.0 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.0 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 0.2 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.1 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.0 GO:0098596 vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.0 0.0 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0002432 granuloma formation(GO:0002432)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.0 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.0 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.5 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.3 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.3 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.0 GO:0005712 chiasma(GO:0005712)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.0 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.0 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.0 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.0 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.9 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.0 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.0 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.2 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.0 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.3 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.3 GO:0003933 GTP cyclohydrolase activity(GO:0003933)
0.1 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.2 GO:0046979 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1 0.2 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.5 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.4 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.3 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.0 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.1 GO:0004854 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0 0.1 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.0 0.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.2 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.0 0.0 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.0 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.1 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.0 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:1990188 euchromatin binding(GO:1990188)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0052630 CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.0 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0045340 mercury ion binding(GO:0045340)
0.0 0.1 GO:0043842 Kdo transferase activity(GO:0043842)
0.0 0.1 GO:0046977 TAP binding(GO:0046977)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.0 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.0 GO:0031711 bradykinin receptor binding(GO:0031711)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.0 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.0 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.0 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0034891 pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0 0.2 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0 0.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.0 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.0 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.0 GO:2001069 glycogen binding(GO:2001069)
0.0 0.0 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.0 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.0 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.0 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.0 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.0 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.0 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.0 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0 0.1 GO:0034869 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.0 GO:1990239 steroid hormone binding(GO:1990239)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.0 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.1 PID ATM PATHWAY ATM pathway
0.0 0.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 0.0 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.1 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.0 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.4 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.0 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.0 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.1 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.0 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME GPCR DOWNSTREAM SIGNALING Genes involved in GPCR downstream signaling
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.0 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.0 REACTOME NEGATIVE REGULATION OF FGFR SIGNALING Genes involved in Negative regulation of FGFR signaling
0.0 0.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling