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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for E2f2_E2f5

Z-value: 1.86

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Transcription factors associated with E2f2_E2f5

Gene Symbol	Gene ID	Gene Info
E2f2 Ensembl NCBI MGI UniProt	ENSMUSG00000018983.9	E2F transcription factor 2
E2f5 Ensembl NCBI MGI UniProt	ENSMUSG00000027552.8	E2F transcription factor 5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr4_136177846_136177997	E2f2	2862	0.194744	0.96	2.8e-03	Click!
chr4_136173497_136173667	E2f2	1188	0.390876	0.91	1.2e-02	Click!
chr4_136174892_136175046	E2f2	2575	0.206801	0.89	1.6e-02	Click!
chr4_136174341_136174511	E2f2	2032	0.244623	0.81	5.3e-02	Click!
chr4_136171513_136171701	E2f2	787	0.552850	0.78	6.5e-02	Click!
chr3_14578527_14578688	E2f5	34	0.966994	0.93	6.8e-03	Click!
chr3_14578695_14579303	E2f5	328	0.845097	0.85	3.0e-02	Click!
chr3_14579339_14579539	E2f5	768	0.561548	-0.77	7.5e-02	Click!
chr3_14579545_14579724	E2f5	963	0.468221	-0.38	4.6e-01	Click!
chr3_14579749_14579900	E2f5	1153	0.399227	-0.33	5.3e-01	Click!

Activity of the E2f2_E2f5 motif across conditions

Conditions sorted by the z-value of the E2f2_E2f5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_98146443_98146601	0.99	Omp	olfactory marker protein	1020	0.47
chr2_156447550_156447712	0.94	Gm14225	predicted gene 14225	23	0.96
chr5_148674254_148674405	0.79	Gm36186	predicted gene, 36186	37137	0.13
chr18_46341760_46341934	0.67	4930415P13Rik	RIKEN cDNA 4930415P13 gene	1418	0.34
chr12_99269518_99269669	0.64	Foxn3	forkhead box N3	21684	0.14
chr5_23413691_23413875	0.58	Gm42509	predicted gene 42509	17680	0.11
chr5_121838276_121838548	0.57	Sh2b3	SH2B adaptor protein 3	766	0.47
chr13_111796213_111796385	0.57	Map3k1	mitogen-activated protein kinase kinase kinase 1	12016	0.14
chr19_7217620_7217775	0.56	Cox8a	cytochrome c oxidase subunit 8A	81	0.95
chr8_33913458_33913624	0.54	Rbpms	RNA binding protein gene with multiple splicing	15735	0.16
chr5_102775781_102775953	0.52	Arhgap24	Rho GTPase activating protein 24	7096	0.31
chr5_139835784_139835950	0.52	Psmg3	proteasome (prosome, macropain) assembly chaperone 3	8982	0.13
chr2_173162438_173162602	0.49	Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	9438	0.17
chr2_22623304_22623471	0.49	Gad2	glutamic acid decarboxylase 2	83	0.96
chr15_79883594_79883768	0.49	AC113595.1	novel transcript, antisense to Apobec3	5851	0.11
chr15_55090420_55090606	0.49	Dscc1	DNA replication and sister chromatid cohesion 1	22	0.97
chr8_49012977_49013144	0.49	Gm45830	predicted gene 45830	31220	0.18
chr11_62487650_62487823	0.48	Gm12278	predicted gene 12278	4939	0.13
chr14_47188793_47188954	0.48	Gch1	GTP cyclohydrolase 1	540	0.62
chr3_96571864_96572239	0.48	Gm16253	predicted gene 16253	4933	0.08
chr4_56961559_56961774	0.48	Tmem245	transmembrane protein 245	14229	0.15
chr15_79683713_79683872	0.47	Gm49520	predicted gene, 49520	2470	0.13
chr7_30360114_30360296	0.46	Lrfn3	leucine rich repeat and fibronectin type III domain containing 3	2567	0.1
chr7_132574591_132574901	0.46	Oat	ornithine aminotransferase	972	0.5
chr6_117758642_117759021	0.45	1700030F04Rik	RIKEN cDNA 1700030F04 gene	7062	0.19
chr11_112779929_112780096	0.45	BC006965	cDNA sequence BC006965	1964	0.28
chr8_12709584_12709755	0.45	Gm15348	predicted gene 15348	9458	0.15
chr7_68915875_68916026	0.44	Gm34664	predicted gene, 34664	56	0.98
chr15_78174003_78174159	0.44	Ift27	intraflagellar transport 27	26	0.85
chr8_70904582_70904751	0.43	Map1s	microtubule-associated protein 1S	1266	0.23
chr19_41661137_41661296	0.43	Slit1	slit guidance ligand 1	52686	0.12
chr9_62358912_62359088	0.43	Anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	7938	0.21
chr19_38930814_38930975	0.42	Hells	helicase, lymphoid specific	21	0.98
chr6_21949358_21949518	0.42	Ing3	inhibitor of growth family, member 3	133	0.97
chr11_79647043_79647213	0.41	Gm24887	predicted gene, 24887	8000	0.11
chr7_28796738_28796906	0.41	Rinl	Ras and Rab interactor-like	116	0.91
chr13_23761471_23761669	0.41	H4c1	H4 clustered histone 1	340	0.53
chr1_36535791_36536054	0.41	Ankrd23	ankyrin repeat domain 23	183	0.87
chr9_77707832_77708042	0.41	Gm47789	predicted gene, 47789	55	0.97
chr2_129800360_129800704	0.40	Stk35	serine/threonine kinase 35	15	0.98
chr2_181288071_181288225	0.39	Gmeb2	glucocorticoid modulatory element binding protein 2	113	0.93
chr11_7215786_7215938	0.39	Igfbp3	insulin-like growth factor binding protein 3	1939	0.32
chr11_119314655_119314806	0.39	Card14	caspase recruitment domain family, member 14	57	0.96
chr6_4747270_4747444	0.39	Peg10	paternally expressed 10	49	0.63
chr17_35736688_35736839	0.39	Gm20443	predicted gene 20443	3043	0.11
chr19_3208419_3208579	0.38	Gm50432	predicted gene, 50432	2706	0.16
chr18_35887757_35887908	0.38	Gm36315	predicted gene, 36315	2505	0.16
chr1_182143366_182143524	0.38	Srp9	signal recognition particle 9	12746	0.15
chr12_84064755_84064929	0.38	Acot5	acyl-CoA thioesterase 5	4483	0.1
chr14_26006324_26006475	0.37	Gm2260	predicted gene 2260	10032	0.12
chr14_26145943_26146094	0.37	Gm2274	predicted gene 2274	10018	0.12
chr14_26285592_26285743	0.37	Gm18578	predicted gene, 18578	17038	0.12
chr4_138972772_138972945	0.37	Tmco4	transmembrane and coiled-coil domains 4	30	0.97
chr11_113619444_113619605	0.36	Sstr2	somatostatin receptor 2	48	0.97
chr12_69228128_69228315	0.36	Pole2	polymerase (DNA directed), epsilon 2 (p59 subunit)	26	0.78
chr4_150087496_150087672	0.36	Gpr157	G protein-coupled receptor 157	219	0.88
chr12_57230408_57230581	0.36	Mipol1	mirror-image polydactyly 1	3	0.56
chr15_89210193_89210346	0.36	Ppp6r2	protein phosphatase 6, regulatory subunit 2	1284	0.29
chr7_110121546_110121775	0.35	Wee1	WEE 1 homolog 1 (S. pombe)	386	0.76
chr13_98352948_98353139	0.35	Foxd1	forkhead box D1	1199	0.4
chr1_51852458_51852609	0.35	Myo1b	myosin IB	1427	0.36
chr1_38130022_38130190	0.35	Rev1	REV1, DNA directed polymerase	305	0.87
chr1_191641728_191641952	0.35	Gm37349	predicted gene, 37349	44193	0.11
chr11_31841101_31841288	0.35	Gm12107	predicted gene 12107	8534	0.19
chr7_141436148_141436439	0.34	Slc25a22	solute carrier family 25 (mitochondrial carrier, glutamate), member 22	896	0.28
chr11_98907623_98907912	0.34	Cdc6	cell division cycle 6	34	0.96
chr4_115497333_115497797	0.34	Cyp4a14	cytochrome P450, family 4, subfamily a, polypeptide 14	1423	0.29
chr14_55822818_55822969	0.34	Nfatc4	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4	251	0.83
chr5_142929156_142929325	0.34	Actb	actin, beta	22486	0.13
chr1_39535294_39535562	0.33	Cnot11	CCR4-NOT transcription complex, subunit 11	374	0.78
chr12_112644432_112644593	0.33	Siva1	SIVA1, apoptosis-inducing factor	167	0.91
chr10_128923068_128923230	0.33	Bloc1s1	biogenesis of lysosomal organelles complex-1, subunit 1	123	0.66
chr16_85801512_85801670	0.33	Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	110	0.97
chr8_114535625_114535816	0.33	Gm16116	predicted gene 16116	59180	0.12
chr4_32615201_32615368	0.33	Casp8ap2	caspase 8 associated protein 2	167	0.93
chr10_53629362_53629531	0.33	Mcm9	minichromosome maintenance 9 homologous recombination repair factor	513	0.69
chr4_19992397_19992575	0.33	4930480G23Rik	RIKEN cDNA 4930480G23 gene	13087	0.19
chr18_75234415_75234580	0.32	Gm8807	predicted gene 8807	51683	0.12
chr7_127477693_127477849	0.32	Fbrs	fibrosin	1428	0.16
chr9_67633131_67633282	0.32	Gm47110	predicted gene, 47110	66975	0.09
chr2_167260546_167260697	0.32	Ptgis	prostaglandin I2 (prostacyclin) synthase	20017	0.13
chr10_127342400_127342556	0.32	Gli1	GLI-Kruppel family member GLI1	504	0.57
chr17_26114147_26114341	0.32	Tmem8	transmembrane protein 8	901	0.34
chr7_113207183_113207355	0.31	Arntl	aryl hydrocarbon receptor nuclear translocator-like	196	0.95
chr9_43742856_43743217	0.31	Nectin1	nectin cell adhesion molecule 1	948	0.41
chr12_85785468_85785654	0.31	Flvcr2	feline leukemia virus subgroup C cellular receptor 2	10731	0.15
chr3_36475062_36475233	0.31	Mir7009	microRNA 7009	377	0.48
chr10_71347555_71347729	0.30	Ipmk	inositol polyphosphate multikinase	121	0.94
chr5_136135624_136135808	0.30	Lrwd1	leucine-rich repeats and WD repeat domain containing 1	281	0.58
chr8_25602056_25602234	0.30	Nsd3	nuclear receptor binding SET domain protein 3	139	0.91
chr15_73512893_73513074	0.30	Dennd3	DENN/MADD domain containing 3	311	0.89
chr11_101376283_101376946	0.30	G6pc	glucose-6-phosphatase, catalytic	9053	0.06
chr12_85473320_85473671	0.30	Fos	FBJ osteosarcoma oncogene	395	0.83
chr2_29035019_29035395	0.29	Cfap77	cilia and flagella associated protein 77	4153	0.2
chr2_34530230_34530406	0.29	Gm13408	predicted gene 13408	34681	0.16
chr5_99233257_99233431	0.29	Rasgef1b	RasGEF domain family, member 1B	722	0.73
chr5_23251952_23252119	0.29	Gm28022	predicted gene, 28022	27876	0.16
chr4_148144119_148144275	0.29	Mad2l2	MAD2 mitotic arrest deficient-like 2	593	0.55
chr13_21263739_21263906	0.28	Gpx5	glutathione peroxidase 5	28909	0.1
chr13_47105847_47106030	0.28	Dek	DEK oncogene (DNA binding)	108	0.84
chr7_102513169_102513356	0.28	Gm8556	predicted gene 8556	7747	0.07
chr14_75776661_75776851	0.28	Slc25a30	solute carrier family 25, member 30	4428	0.18
chr15_89378320_89378514	0.28	Odf3b	outer dense fiber of sperm tails 3B	191	0.83
chr7_19003930_19004083	0.28	Irf2bp1	interferon regulatory factor 2 binding protein 1	38	0.93
chr4_136144637_136144812	0.28	Id3	inhibitor of DNA binding 3	250	0.89
chr4_106910825_106910982	0.28	Ssbp3	single-stranded DNA binding protein 3	202	0.95
chr5_31093528_31093698	0.28	Slc30a3	solute carrier family 30 (zinc transporter), member 3	2	0.93
chr19_55315246_55315409	0.28	Zdhhc6	zinc finger, DHHC domain containing 6	661	0.54
chr2_156457486_156457755	0.28	Gm14224	predicted gene 14224	1969	0.21
chr4_117279354_117279512	0.28	Rnf220	ring finger protein 220	5650	0.12
chr9_66154137_66154300	0.28	Dapk2	death-associated protein kinase 2	4005	0.21
chr8_70798408_70798701	0.27	Mir7240	microRNA 7240	419	0.6
chr17_65884967_65885131	0.27	Ralbp1	ralA binding protein 1	95	0.87
chr13_59769326_59769477	0.27	Isca1	iron-sulfur cluster assembly 1	76	0.51
chr5_65698209_65698394	0.27	Pds5a	PDS5 cohesin associated factor A	28	0.96
chr19_47348741_47348901	0.27	Sh3pxd2a	SH3 and PX domains 2A	34070	0.15
chr17_80096445_80096646	0.27	Gm23125	predicted gene, 23125	8392	0.15
chr3_121885017_121885175	0.27	Gm42593	predicted gene 42593	22254	0.15
chr7_127260691_127261039	0.27	Dctpp1	dCTP pyrophosphatase 1	156	0.87
chr17_29094634_29094798	0.27	1700023B13Rik	RIKEN cDNA 1700023B13 gene	255	0.77
chrX_101386546_101386756	0.27	Gjb1	gap junction protein, beta 1	2915	0.19
chr11_26593152_26593346	0.26	Gm6899	predicted gene 6899	8	0.85
chr13_60735844_60736400	0.26	Dapk1	death associated protein kinase 1	17874	0.15
chr2_119594156_119594317	0.26	Oip5os1	Opa interacting protein 5, opposite strand 1	61	0.95
chr18_76378806_76378977	0.26	Gm50360	predicted gene, 50360	57067	0.14
chr9_37250045_37250299	0.26	Gm10177	predicted gene 10177	2750	0.13
chr9_108913748_108913914	0.26	Tmem89	transmembrane protein 89	788	0.4
chr4_123587519_123587873	0.26	Macf1	microtubule-actin crosslinking factor 1	14636	0.16
chr5_8998054_8998225	0.26	Crot	carnitine O-octanoyltransferase	815	0.35
chr3_52401175_52401340	0.26	Gm38098	predicted gene, 38098	24151	0.2
chr14_73325714_73325873	0.26	Rb1	RB transcriptional corepressor 1	29	0.98
chr1_10038112_10038275	0.26	Cspp1	centrosome and spindle pole associated protein 1	24	0.49
chr11_57983626_57984029	0.26	Gm12249	predicted gene 12249	10693	0.15
chr18_20946424_20946594	0.26	Rnf125	ring finger protein 125	1884	0.37
chr10_75411837_75412000	0.26	Upb1	ureidopropionase, beta	1875	0.32
chr4_97775109_97775447	0.26	Nfia	nuclear factor I/A	2330	0.28
chr4_119338935_119339105	0.26	Ldha-ps2	lactate dehydrogenase A, pseudogene 2	3575	0.13
chr13_23533566_23533905	0.25	H2ac10	H2A clustered histone 10	171	0.69
chr7_84152712_84152872	0.25	Gm26708	predicted gene, 26708	434	0.66
chr11_8456578_8456775	0.25	Tns3	tensin 3	11999	0.28
chr17_24360969_24361287	0.25	Gm25618	predicted gene, 25618	1416	0.24
chr19_55851785_55852196	0.25	Ppnr	per-pentamer repeat gene	10318	0.25
chr13_41240987_41241148	0.25	Gm32063	predicted gene, 32063	4722	0.13
chr5_138171911_138172068	0.25	Ap4m1	adaptor-related protein complex AP-4, mu 1	13	0.66
chr13_97439501_97439676	0.25	Lncenc1	long non-coding RNA, embryonic stem cells expressed 1	4618	0.2
chr7_48881274_48881434	0.25	Gm2788	predicted gene 2788	54	0.74
chr11_3124565_3124716	0.25	Pisd-ps1	phosphatidylserine decarboxylase, pseudogene 1	1264	0.37
chrX_134757024_134757175	0.25	Armcx3	armadillo repeat containing, X-linked 3	452	0.46
chr9_22071373_22071540	0.25	Zfp653	zinc finger protein 653	80	0.59
chr8_104007719_104007879	0.24	Gm8748	predicted gene 8748	63350	0.1
chr9_36767746_36767915	0.24	Gm26787	predicted gene, 26787	57	0.62
chr10_75475521_75475953	0.24	Gm48158	predicted gene, 48158	7655	0.13
chr17_26115707_26115872	0.24	Tmem8	transmembrane protein 8	842	0.37
chr7_141327534_141327875	0.24	Deaf1	DEAF1, transcription factor	14	0.5
chr17_34632326_34632509	0.24	Prrt1	proline-rich transmembrane protein 1	1013	0.22
chr9_100643293_100643491	0.24	Stag1	stromal antigen 1	56	0.97
chr16_91045477_91045695	0.24	4931406G06Rik	RIKEN cDNA 4931406G06 gene	930	0.33
chr1_190175489_190175675	0.24	Prox1	prospero homeobox 1	4868	0.2
chr4_44016840_44017006	0.24	Clta	clathrin, light polypeptide (Lca)	4237	0.17
chr6_21850864_21851024	0.24	Tspan12	tetraspanin 12	884	0.5
chr2_167574964_167575153	0.24	Gm11475	predicted gene 11475	16337	0.11
chr12_82914756_82914931	0.24	1700085C21Rik	RIKEN cDNA 1700085C21 gene	24312	0.21
chr2_157204467_157204627	0.24	Rbl1	RB transcriptional corepressor like 1	13	0.97
chr11_98770256_98770457	0.24	Nr1d1	nuclear receptor subfamily 1, group D, member 1	70	0.94
chr4_136116896_136117047	0.24	Gm26001	predicted gene, 26001	20525	0.12
chr17_23564159_23564327	0.24	Zfp213	zinc finger protein 213	5	0.94
chr3_132917460_132917629	0.23	Npnt	nephronectin	11185	0.16
chr19_57404259_57404416	0.23	Gm50271	predicted gene, 50271	19157	0.15
chr13_112067503_112067855	0.23	Gm15323	predicted gene 15323	62177	0.1
chr11_74832597_74832764	0.23	Mnt	max binding protein	1760	0.25
chr2_158154122_158154310	0.23	Tgm2	transglutaminase 2, C polypeptide	7780	0.16
chr8_115705724_115706077	0.23	Gm15655	predicted gene 15655	822	0.53
chr17_7284590_7284752	0.23	Rps6ka2	ribosomal protein S6 kinase, polypeptide 2	24035	0.14
chr14_61046171_61046349	0.23	Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	209	0.95
chr3_57510454_57510634	0.23	Gm16016	predicted gene 16016	17688	0.18
chr3_127552939_127553105	0.23	Larp7	La ribonucleoprotein domain family, member 7	175	0.73
chr11_99265900_99266173	0.23	Krt24	keratin 24	19226	0.1
chr11_53299774_53299939	0.23	Hspa4	heat shock protein 4	555	0.71
chr10_20313109_20313327	0.23	Bclaf1	BCL2-associated transcription factor 1	681	0.44
chr8_14246635_14246869	0.23	Gm26184	predicted gene, 26184	26559	0.19
chr7_101821639_101821825	0.23	Phox2a	paired-like homeobox 2a	986	0.33
chr1_181475926_181476204	0.23	Ccdc121	coiled-coil domain containing 121	35386	0.14
chr4_155560766_155560966	0.23	Nadk	NAD kinase	1512	0.26
chr1_121297951_121298102	0.23	Gm38283	predicted gene, 38283	2805	0.24
chr11_9011065_9011245	0.23	Hus1	HUS1 checkpoint clamp component	5	0.98
chr8_41173404_41173555	0.23	Mtus1	mitochondrial tumor suppressor 1	39753	0.13
chr2_126566874_126567095	0.23	Slc27a2	solute carrier family 27 (fatty acid transporter), member 2	2224	0.3
chr14_54417307_54417458	0.22	Slc7a7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7	297	0.79
chr6_47191400_47191564	0.22	Cntnap2	contactin associated protein-like 2	52905	0.16
chr11_109473897_109474065	0.22	Slc16a6	solute carrier family 16 (monocarboxylic acid transporters), member 6	383	0.59
chr2_126152340_126152692	0.22	Dtwd1	DTW domain containing 1	375	0.59
chr19_3669127_3669720	0.22	Lrp5	low density lipoprotein receptor-related protein 5	17133	0.12
chr4_34613649_34613810	0.22	Orc3	origin recognition complex, subunit 3	1164	0.36
chr16_18248703_18248876	0.22	Ranbp1	RAN binding protein 1	57	0.51
chr18_77714097_77714328	0.22	4930465K10Rik	RIKEN cDNA 4930465K10 gene	2	0.75
chr7_19495565_19495804	0.22	Exoc3l2	exocyst complex component 3-like 2	6628	0.08
chr2_168735267_168735535	0.22	Atp9a	ATPase, class II, type 9A	1062	0.52
chr11_97745116_97745280	0.22	Mir8102	microRNA 8102	301	0.57
chr3_24333217_24333384	0.22	Gm7536	predicted gene 7536	232	0.97
chr11_116808351_116808519	0.22	Mxra7	matrix-remodelling associated 7	19568	0.1

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f2_E2f5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.1	0.4	GO:0034421	post-translational protein acetylation(GO:0034421)
0.1	0.9	GO:0097501	stress response to metal ion(GO:0097501)
0.1	0.6	GO:0031508	pericentric heterochromatin assembly(GO:0031508)
0.1	0.4	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.3	GO:0060137	maternal process involved in parturition(GO:0060137)
0.1	0.4	GO:0006538	glutamate catabolic process(GO:0006538)
0.1	0.3	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1	0.2	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1	0.3	GO:0001543	ovarian follicle rupture(GO:0001543)
0.1	0.2	GO:0097360	chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1	0.3	GO:1904217	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1	0.3	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.1	0.2	GO:0048320	axial mesoderm formation(GO:0048320)
0.1	0.3	GO:0006285	base-excision repair, AP site formation(GO:0006285)
0.1	0.7	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1	0.3	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1	0.2	GO:0044778	meiotic DNA integrity checkpoint(GO:0044778)
0.1	0.2	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1	0.2	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.1	0.2	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1	0.2	GO:0030242	pexophagy(GO:0030242)
0.1	0.2	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.1	0.2	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1	0.2	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.1	0.2	GO:0032789	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.1	0.2	GO:0021558	trochlear nerve development(GO:0021558)
0.1	0.2	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.1	0.2	GO:0046292	formaldehyde metabolic process(GO:0046292)
0.1	1.0	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.1	0.4	GO:0060897	neural plate regionalization(GO:0060897)
0.1	0.2	GO:0034214	protein hexamerization(GO:0034214)
0.1	0.1	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1	0.2	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.1	0.2	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1	0.1	GO:0035983	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.1	0.2	GO:0007418	ventral midline development(GO:0007418)
0.1	0.2	GO:0048254	snoRNA localization(GO:0048254)
0.1	0.3	GO:0051775	response to redox state(GO:0051775)
0.1	0.2	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.1	0.2	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.1	0.2	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.1	0.2	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1	0.3	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.0	0.4	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.0	0.1	GO:0018992	germ-line sex determination(GO:0018992)
0.0	0.1	GO:0010911	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	0.2	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.2	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	0.2	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.1	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.2	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.1	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.0	0.2	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.2	GO:0033762	response to glucagon(GO:0033762)
0.0	0.4	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.3	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.2	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.1	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:0060066	oviduct development(GO:0060066)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.2	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
0.0	0.4	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.2	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.3	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.2	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.2	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045)
0.0	0.2	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:2000409	positive regulation of T cell extravasation(GO:2000409)
0.0	0.0	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.0	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.0	0.1	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0	0.1	GO:1902512	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.2	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.2	GO:0000820	regulation of glutamine family amino acid metabolic process(GO:0000820)
0.0	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0070900	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0	0.5	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.0	0.1	GO:0040031	snRNA modification(GO:0040031)
0.0	0.1	GO:0010909	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0	0.1	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.0	GO:0007403	glial cell fate determination(GO:0007403)
0.0	0.2	GO:0060033	anatomical structure regression(GO:0060033)
0.0	0.1	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.3	GO:0030432	peristalsis(GO:0030432)
0.0	0.1	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210)
0.0	0.2	GO:0006621	protein retention in ER lumen(GO:0006621)
0.0	0.3	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
0.0	0.2	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0	0.2	GO:0002154	thyroid hormone mediated signaling pathway(GO:0002154)
0.0	0.1	GO:0021586	pons maturation(GO:0021586)
0.0	0.2	GO:1904415	regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.0	0.2	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.1	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0090306	spindle assembly involved in meiosis(GO:0090306)
0.0	0.1	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.0	0.2	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0	0.1	GO:0010159	specification of organ position(GO:0010159)
0.0	0.1	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.0	0.3	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.1	GO:0009115	xanthine catabolic process(GO:0009115)
0.0	0.4	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.1	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0015744	succinate transport(GO:0015744)
0.0	0.1	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.1	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.0	0.3	GO:1902895	positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0	0.1	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0	0.1	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0	0.2	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.2	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.0	0.1	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.3	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.1	GO:0045472	response to ether(GO:0045472)
0.0	0.1	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.0	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.0	0.3	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.0	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.1	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.2	GO:0002934	desmosome organization(GO:0002934)
0.0	0.0	GO:0046864	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0	0.1	GO:0060264	regulation of respiratory burst involved in inflammatory response(GO:0060264)
0.0	0.1	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.1	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.0	GO:1902065	response to L-glutamate(GO:1902065)
0.0	0.1	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
0.0	0.1	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.0	0.1	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.1	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.1	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.1	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	0.1	GO:1903999	negative regulation of eating behavior(GO:1903999)
0.0	0.0	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0	0.1	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.0	0.1	GO:0061623	galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.1	GO:0061156	pulmonary artery morphogenesis(GO:0061156)
0.0	0.1	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.0	GO:0003166	bundle of His development(GO:0003166)
0.0	0.1	GO:0071888	macrophage apoptotic process(GO:0071888) regulation of macrophage apoptotic process(GO:2000109)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.2	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0019287	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.1	GO:1904502	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0	0.0	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.0	GO:0021888	hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0	0.6	GO:0071398	cellular response to fatty acid(GO:0071398)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.1	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.1	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0	0.2	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.2	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	0.1	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.0	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0	0.2	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:1990928	response to amino acid starvation(GO:1990928)
0.0	0.1	GO:1903894	regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.0	0.1	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0	0.1	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.2	GO:0097237	cellular response to toxic substance(GO:0097237)
0.0	0.0	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.1	GO:0072429	response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0	0.1	GO:1903242	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0	0.3	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.1	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.0	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.0	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0086042	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
0.0	0.0	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282)
0.0	0.1	GO:0015888	thiamine transport(GO:0015888)
0.0	0.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.1	GO:0090166	Golgi disassembly(GO:0090166)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.0	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.0	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.0	0.1	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.2	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.1	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.1	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.0	0.1	GO:1903802	L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.0	0.1	GO:0002277	myeloid dendritic cell activation involved in immune response(GO:0002277)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.0	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	0.1	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.2	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.0	0.1	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.0	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0	0.1	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.0	0.1	GO:1905065	regulation of vascular smooth muscle cell differentiation(GO:1905063) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.0	0.1	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0090579	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0	0.0	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.0	GO:0042167	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.1	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.1	GO:0031441	negative regulation of mRNA 3'-end processing(GO:0031441)
0.0	0.4	GO:0051875	pigment granule localization(GO:0051875)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.0	0.1	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.1	GO:0048023	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0	0.0	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0	0.1	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	0.1	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.0	0.1	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.0	0.1	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0	0.1	GO:0046070	dGTP metabolic process(GO:0046070)
0.0	0.1	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.0	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.1	GO:1903660	complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.1	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.0	0.0	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.0	GO:0060268	negative regulation of respiratory burst(GO:0060268)
0.0	0.0	GO:0051204	protein insertion into mitochondrial membrane(GO:0051204)
0.0	0.1	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.0	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.0	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.0	0.0	GO:1904683	regulation of metalloendopeptidase activity(GO:1904683) negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0	0.0	GO:0090360	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.0	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.0	GO:0061144	alveolar secondary septum development(GO:0061144)
0.0	0.0	GO:0009080	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
0.0	0.1	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	0.0	GO:0032348	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0	0.1	GO:1901317	regulation of sperm motility(GO:1901317)
0.0	0.0	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
0.0	0.2	GO:0042407	cristae formation(GO:0042407)
0.0	0.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.1	GO:0070126	mitochondrial translational termination(GO:0070126)
0.0	0.0	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.1	GO:2000002	negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002)
0.0	0.2	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.0	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:1901679	nucleotide transmembrane transport(GO:1901679)
0.0	0.0	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0	0.0	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
0.0	0.0	GO:0006566	threonine metabolic process(GO:0006566)
0.0	0.1	GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0	0.2	GO:0048490	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0	0.1	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.0	0.0	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.1	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.1	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.1	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.1	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.0	0.2	GO:0030497	fatty acid elongation(GO:0030497)
0.0	0.1	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0	0.1	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.0	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0	0.0	GO:0043201	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0	0.1	GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0	0.1	GO:0061668	mitochondrial ribosome assembly(GO:0061668)
0.0	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.0	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.0	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.0	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.0	GO:0035425	autocrine signaling(GO:0035425)
0.0	0.0	GO:0070268	cornification(GO:0070268)
0.0	0.2	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0	0.1	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0	0.0	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	0.1	GO:0010528	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0	0.1	GO:0010994	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0	0.1	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0	0.0	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.1	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.0	GO:1905097	regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0	0.0	GO:1990791	dorsal root ganglion development(GO:1990791)
0.0	0.4	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.0	0.0	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.0	0.1	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0	0.0	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.0	GO:0046146	tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.0	GO:1903599	positive regulation of mitophagy(GO:1903599)
0.0	0.0	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.0	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:0002741	positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.0	0.1	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.0	GO:0051660	establishment of centrosome localization(GO:0051660)
0.0	0.0	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.2	GO:0071548	response to dexamethasone(GO:0071548) cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.0	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.1	GO:0043312	neutrophil degranulation(GO:0043312)
0.0	0.1	GO:0006744	ubiquinone biosynthetic process(GO:0006744)
0.0	0.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.1	GO:0030828	positive regulation of cGMP biosynthetic process(GO:0030828)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0044362	modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.0	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0	0.0	GO:0071638	negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0	0.0	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.0	0.1	GO:0000478	endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0060242	contact inhibition(GO:0060242)
0.0	0.0	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0	0.0	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.0	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.0	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.0	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.0	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.0	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.0	GO:0021636	trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637)
0.0	0.1	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
0.0	0.1	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.1	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.0	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.1	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.0	0.0	GO:0034476	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0	0.1	GO:0014857	regulation of skeletal muscle satellite cell proliferation(GO:0014842) regulation of skeletal muscle cell proliferation(GO:0014857)
0.0	0.1	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.0	GO:0006235	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0	0.0	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.0	GO:0051795	regulation of catagen(GO:0051794) positive regulation of catagen(GO:0051795)
0.0	0.0	GO:0019042	viral latency(GO:0019042)
0.0	0.2	GO:0060074	synapse maturation(GO:0060074)
0.0	0.1	GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872)
0.0	0.0	GO:0072697	protein localization to cell cortex(GO:0072697)
0.0	0.0	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.0	0.0	GO:0010288	response to lead ion(GO:0010288)
0.0	0.0	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.1	GO:0001553	luteinization(GO:0001553)
0.0	0.0	GO:0048382	mesendoderm development(GO:0048382)
0.0	0.1	GO:0035493	SNARE complex assembly(GO:0035493)
0.0	0.0	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.0	GO:0034140	negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0	0.1	GO:0002484	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.0	0.0	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0	0.0	GO:0098535	de novo centriole assembly(GO:0098535)
0.0	0.1	GO:0006536	glutamate metabolic process(GO:0006536)
0.0	0.2	GO:0051443	positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0	0.1	GO:0034382	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.0	GO:0098596	vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.0	0.0	GO:0002035	brain renin-angiotensin system(GO:0002035)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0002432	granuloma formation(GO:0002432)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.0	0.0	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.0	0.0	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.2	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.1	0.5	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.1	0.3	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1	0.6	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.1	0.3	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.1	0.2	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.2	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.2	GO:0031261	DNA replication preinitiation complex(GO:0031261)
0.0	0.2	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0031523	Myb complex(GO:0031523)
0.0	0.1	GO:0043293	apoptosome(GO:0043293)
0.0	0.1	GO:0044393	microspike(GO:0044393)
0.0	0.3	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.2	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.3	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.5	GO:0033391	chromatoid body(GO:0033391)
0.0	0.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.2	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.2	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.3	GO:0097542	ciliary tip(GO:0097542)
0.0	0.1	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.5	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0032021	NELF complex(GO:0032021)
0.0	0.1	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.2	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.4	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.4	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.1	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.1	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.2	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.3	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.2	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0071439	clathrin complex(GO:0071439)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.1	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.1	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.1	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.0	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.0	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.1	GO:0000235	astral microtubule(GO:0000235)
0.0	0.2	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.3	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.0	GO:0005712	chiasma(GO:0005712)
0.0	0.1	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.0	0.0	GO:1990761	growth cone lamellipodium(GO:1990761)
0.0	0.0	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0061617	MICOS complex(GO:0061617)
0.0	0.0	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.0	0.0	GO:0098553	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0	0.9	GO:0016605	PML body(GO:0016605)
0.0	0.1	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.1	GO:0031415	NatA complex(GO:0031415)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.1	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	0.0	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.0	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.0	0.7	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.0	GO:0038037	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.2	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.4	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.2	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.1	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.4	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	0.2	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.0	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	0.3	GO:0070840	dynein complex binding(GO:0070840)
0.1	0.4	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.2	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1	0.4	GO:0004994	somatostatin receptor activity(GO:0004994)
0.1	0.3	GO:0003933	GTP cyclohydrolase activity(GO:0003933)
0.1	0.2	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1	0.2	GO:0046979	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1	0.2	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1	0.2	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.1	0.4	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.2	GO:0036033	mediator complex binding(GO:0036033)
0.1	0.5	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1	0.2	GO:0034511	U3 snoRNA binding(GO:0034511)
0.1	0.2	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.1	0.2	GO:1901612	cardiolipin binding(GO:1901612)
0.0	0.3	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.6	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.4	GO:0031432	titin binding(GO:0031432)
0.0	0.3	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.3	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0019961	interferon binding(GO:0019961)
0.0	0.0	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.5	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0070698	type I activin receptor binding(GO:0070698)
0.0	0.3	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.1	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0	0.1	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0	0.4	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.3	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.4	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.1	GO:0004854	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0	0.1	GO:0015087	cobalt ion transmembrane transporter activity(GO:0015087)
0.0	0.1	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.2	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.1	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.0	0.0	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.0	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.0	0.2	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.2	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0	0.1	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.0	0.1	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.3	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.1	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0	0.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.1	GO:0070051	fibrinogen binding(GO:0070051)
0.0	0.1	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0	0.1	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0	0.1	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.5	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.0	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.0	0.1	GO:0070538	oleic acid binding(GO:0070538)
0.0	0.1	GO:1990188	euchromatin binding(GO:1990188)
0.0	0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.5	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0000150	recombinase activity(GO:0000150)
0.0	0.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0089720	caspase binding(GO:0089720)
0.0	0.0	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0052630	CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.0	0.2	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.1	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.0	0.1	GO:0070905	serine binding(GO:0070905)
0.0	0.1	GO:0030572	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.0	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.0	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0045340	mercury ion binding(GO:0045340)
0.0	0.1	GO:0043842	Kdo transferase activity(GO:0043842)
0.0	0.1	GO:0046977	TAP binding(GO:0046977)
0.0	0.1	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.7	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.2	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.0	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.3	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.0	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.3	GO:0008483	transaminase activity(GO:0008483)
0.0	0.0	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.4	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.0	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.0	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.0	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.0	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.0	0.1	GO:1990932	5.8S rRNA binding(GO:1990932)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.0	GO:0019770	IgG receptor activity(GO:0019770)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.0	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.2	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0034891	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0	0.2	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.1	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0	0.0	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.2	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.0	GO:0035514	DNA demethylase activity(GO:0035514)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.0	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.0	GO:2001069	glycogen binding(GO:2001069)
0.0	0.0	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.0	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.0	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.0	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.0	0.1	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.1	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.0	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0071253	connexin binding(GO:0071253)
0.0	0.0	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.6	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.1	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.0	GO:0071209	U7 snRNA binding(GO:0071209)
0.0	0.0	GO:0005350	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.1	GO:0034869	2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.0	0.3	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.0	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.2	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.0	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.0	GO:1990239	steroid hormone binding(GO:1990239)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.7	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.7	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.3	PID ATR PATHWAY	ATR signaling pathway
0.4	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.4	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.2	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.3	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.4	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	PID ATM PATHWAY	ATM pathway
0.8	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.3	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.5	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.2	PID MYC PATHWAY	C-MYC pathway
0.0	PID ALK2 PATHWAY	ALK2 signaling events
0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.2	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.3	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX	Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.1	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1	1.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.2	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.0	REACTOME SIGNALING BY ERBB4	Genes involved in Signaling by ERBB4
0.0	0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.5	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.5	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.4	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.0	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.1	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.4	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.0	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.1	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.2	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.3	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.1	REACTOME GPCR DOWNSTREAM SIGNALING	Genes involved in GPCR downstream signaling
0.0	0.3	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.0	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.0	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	0.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.0	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.0	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.0	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.0	REACTOME NEGATIVE REGULATION OF FGFR SIGNALING	Genes involved in Negative regulation of FGFR signaling
0.0	0.3	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling

Results for E2f2_E2f5

Z-value: 1.86

Motif logo

Transcription factors associated with E2f2_E2f5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the E2f2_E2f5 motif across conditions

Conditions sorted by the z-value of the E2f2_E2f5 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f2_E2f5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: