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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for E2f6

Z-value: 1.76

Motif logo

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Transcription factors associated with E2f6

Gene Symbol Gene ID Gene Info
E2f6
ENSMUSG00000057469.7 E2F transcription factor 6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr12_16810873_16811068E2f610.968976-0.954.1e-03Click!
chr12_16811105_16811267E2f6220.968365-0.834.3e-02Click!
chr12_16811292_16811447E2f62050.916756-0.721.1e-01Click!
chr12_16836304_16836455E2f6122280.1374910.424.1e-01Click!
chr12_16828657_16829045E2f647000.162460-0.079.0e-01Click!

Activity of the E2f6 motif across conditions

Conditions sorted by the z-value of the E2f6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_29806024_29806429 1.25 9930021J03Rik
 RIKEN cDNA 9930021J03 gene
 237
 0.69
chrY_90784776_90785079 1.01 Gm47283
 predicted gene, 47283
 16
 0.98
chr3_37419572_37419987 0.96 Spata5
 spermatogenesis associated 5
 117
 0.59
chr15_102470710_102471029 0.93 Pcbp2
 poly(rC) binding protein 2
 84
 0.94
chr1_37864873_37865372 0.89 Tsga10
 testis specific 10
 43
 0.67
chrX_170009846_170010189 0.84 Erdr1
 erythroid differentiation regulator 1
 22
 0.97
chr9_44709221_44709515 0.84 Phldb1
 pleckstrin homology like domain, family B, member 1
 941
 0.33
chr12_110381296_110381622 0.74 Gm47195
 predicted gene, 47195
 56074
 0.08
chr7_127026907_127027653 0.70 Maz
 MYC-associated zinc finger protein (purine-binding transcription factor)
 243
 0.69
chr6_17636992_17637388 0.70 Capza2
 capping protein (actin filament) muscle Z-line, alpha 2
 77
 0.97
chrX_12761746_12762400 0.70 Med14
 mediator complex subunit 14
 0
 0.73
chr14_31217734_31217896 0.69 Sema3g
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
 45
 0.92
chr11_120378223_120379003 0.60 Faap100
 Fanconi anemia core complex associated protein 100
 96
 0.92
chr12_25140626_25140792 0.59 Gm36287
 predicted gene, 36287
 10206
 0.16
chr5_129941480_129942081 0.58 Vkorc1l1
 vitamin K epoxide reductase complex, subunit 1-like 1
 190
 0.89
chr3_89090782_89091135 0.56 Rusc1
 RUN and SH3 domain containing 1
 913
 0.34
chr11_53818731_53818912 0.54 Gm12216
 predicted gene 12216
 22946
 0.11
chr7_44815923_44816372 0.54 Nup62
 nucleoporin 62
 59
 0.66
chr9_98424555_98424727 0.54 Rbp1
 retinol binding protein 1, cellular
 1680
 0.4
chr14_25378261_25378665 0.54 Gm26660
 predicted gene, 26660
 172
 0.96
chr9_107657905_107658551 0.52 Slc38a3
 solute carrier family 38, member 3
 967
 0.31
chr13_24316648_24316847 0.50 Gm23340
 predicted gene, 23340
 105
 0.94
chr6_147638472_147638628 0.48 1700049E15Rik
 RIKEN cDNA 1700049E15 gene
 51691
 0.14
chr18_65989569_65989860 0.48 Lman1
 lectin, mannose-binding, 1
 3946
 0.15
chr6_120665412_120665778 0.48 Cecr2
 CECR2, histone acetyl-lysine reader
 774
 0.66
chr4_59549239_59549668 0.47 Ptbp3
 polypyrimidine tract binding protein 3
 89
 0.76
chr11_119052774_119052944 0.47 Cbx8
 chromobox 8
 11890
 0.15
chr11_58199124_58199368 0.47 Igtp
 interferon gamma induced GTPase
 310
 0.51
chr5_138857853_138858235 0.46 Gm5294
 predicted gene 5294
 37964
 0.15
chrX_42068446_42068784 0.46 Xiap
 X-linked inhibitor of apoptosis
 140
 0.97
chr15_102098310_102098461 0.44 Tns2
 tensin 2
 2028
 0.2
chr15_98732323_98732512 0.43 Fkbp11
 FK506 binding protein 11
 4219
 0.11
chr10_126900802_126900994 0.42 Atp23
 ATP23 metallopeptidase and ATP synthase assembly factor homolog
 450
 0.74
chrX_162888665_162888826 0.42 Syap1
 synapse associated protein 1
 298
 0.83
chr8_74993902_74994396 0.41 Hmgxb4
 HMG box domain containing 4
 437
 0.82
chr5_86172358_86172795 0.41 Uba6
 ubiquitin-like modifier activating enzyme 6
 65
 0.97
chr7_31008253_31008404 0.41 Fam187b
 family with sequence similarity 187, member B
 26458
 0.06
chr11_90418039_90418197 0.41 Hlf
 hepatic leukemia factor
 27223
 0.21
chr15_79690269_79690868 0.41 Gtpbp1
 GTP binding protein 1
 277
 0.78
chr4_57916402_57916601 0.40 D630039A03Rik
 RIKEN cDNA D630039A03 gene
 204
 0.94
chr11_97798801_97799320 0.40 Lasp1
 LIM and SH3 protein 1
 60
 0.94
chrX_94234532_94234995 0.39 Klhl15
 kelch-like 15
 159
 0.94
chr11_16817302_16817617 0.39 Egfros
 epidermal growth factor receptor, opposite strand
 13243
 0.21
chr6_67267595_67268050 0.38 Serbp1
 serpine1 mRNA binding protein 1
 492
 0.74
chr11_120814677_120814902 0.38 Fasn
 fatty acid synthase
 666
 0.5
chr13_36736119_36736534 0.38 Nrn1
 neuritin 1
 1195
 0.44
chr10_108161776_108162265 0.38 Ppp1r12a
 protein phosphatase 1, regulatory subunit 12A
 173
 0.96
chr8_105170716_105171167 0.38 Cbfb
 core binding factor beta
 4
 0.94
chr1_151500754_151501127 0.37 Rnf2
 ring finger protein 2
 15
 0.95
chr9_51008973_51009376 0.37 Sik2
 salt inducible kinase 2
 101
 0.97
chr2_68873804_68874167 0.36 Cers6
 ceramide synthase 6
 12399
 0.14
chr5_22344788_22344947 0.36 Reln
 reelin
 165
 0.94
chr11_70653511_70654114 0.36 Pfn1
 profilin 1
 786
 0.31
chr8_91706641_91706804 0.35 Gm36325
 predicted gene, 36325
 7691
 0.14
chr19_41482156_41482948 0.35 Lcor
 ligand dependent nuclear receptor corepressor
 85
 0.98
chr9_59036274_59036848 0.35 Neo1
 neogenin
 120
 0.98
chr3_107256063_107256233 0.34 Prok1
 prokineticin 1
 16441
 0.12
chr18_76301148_76301315 0.34 Gm50360
 predicted gene, 50360
 20593
 0.19
chr7_36697808_36698005 0.34 Tshz3
 teashirt zinc finger family member 3
 212
 0.9
chr6_99734849_99735003 0.34 Prok2
 prokineticin 2
 8534
 0.15
chr13_23551584_23551775 0.33 H4c6
 H4 clustered histone 6
 31
 0.89
chr12_102757157_102757358 0.33 Gm28051
 predicted gene, 28051
 508
 0.32
chr5_113148745_113149067 0.33 Gm42161
 predicted gene, 42161
 3578
 0.14
chr2_25698782_25698956 0.33 Obp2a
 odorant binding protein 2A
 1174
 0.24
chr15_27487150_27487338 0.33 Tiaf2
 TGF-beta1-induced anti-apoptotic factor 2
 8238
 0.16
chr7_28957656_28957827 0.33 Actn4
 actinin alpha 4
 4482
 0.12
chr6_146155065_146155230 0.32 Itpr2
 inositol 1,4,5-triphosphate receptor 2
 7939
 0.27
chr9_64340286_64341080 0.32 Dis3l
 DIS3 like exosome 3'-5' exoribonuclease
 80
 0.97
chr3_8753511_8753662 0.32 Gm37647
 predicted gene, 37647
 6762
 0.19
chr10_53378945_53379463 0.32 Gm47641
 predicted gene, 47641
 248
 0.79
chr10_81524333_81524508 0.32 Gna15
 guanine nucleotide binding protein, alpha 15
 195
 0.8
chr5_135573104_135573267 0.32 Ccl24
 chemokine (C-C motif) ligand 24
 136
 0.94
chr10_86923470_86923734 0.32 Gm16270
 predicted gene 16270
 14123
 0.13
chr8_109737291_109737613 0.32 Atxn1l
 ataxin 1-like
 270
 0.89
chr1_190169557_190169709 0.32 Prox1
 prospero homeobox 1
 234
 0.76
chr2_79254950_79255348 0.32 Itga4
 integrin alpha 4
 277
 0.94
chr4_133967208_133967543 0.31 Hmgn2
 high mobility group nucleosomal binding domain 2
 66
 0.96
chr7_31128675_31128826 0.31 Scn1b
 sodium channel, voltage-gated, type I, beta
 1747
 0.19
chr12_118301006_118301192 0.31 Sp4
 trans-acting transcription factor 4
 269
 0.95
chr2_121427610_121427761 0.31 Pdia3
 protein disulfide isomerase associated 3
 3055
 0.1
chr15_38299429_38299762 0.31 Klf10
 Kruppel-like factor 10
 200
 0.91
chr15_59012963_59013142 0.31 Mtss1
 MTSS I-BAR domain containing 1
 27544
 0.15
chr5_144255609_144256174 0.31 2900089D17Rik
 RIKEN cDNA 2900089D17 gene
 295
 0.71
chr13_74121256_74121414 0.31 Slc9a3
 solute carrier family 9 (sodium/hydrogen exchanger), member 3
 122
 0.96
chr11_5906116_5906267 0.31 Gck
 glucokinase
 4104
 0.13
chr17_45882790_45882986 0.30 4930542M03Rik
 RIKEN cDNA 4930542M03 gene
 1436
 0.35
chr2_128698686_128698859 0.30 Mertk
 MER proto-oncogene tyrosine kinase
 184
 0.94
chr8_107096349_107096693 0.29 Terf2
 telomeric repeat binding factor 2
 7
 0.86
chr10_18368209_18368416 0.29 Nhsl1
 NHS-like 1
 22010
 0.18
chr13_9764358_9764721 0.29 Zmynd11
 zinc finger, MYND domain containing 11
 51
 0.97
chr17_80728516_80728734 0.29 Map4k3
 mitogen-activated protein kinase kinase kinase kinase 3
 140
 0.84
chr3_130410150_130410482 0.29 Col25a1
 collagen, type XXV, alpha 1
 68500
 0.11
chr8_95357230_95357503 0.29 Mmp15
 matrix metallopeptidase 15
 5098
 0.14
chr5_108694583_108695258 0.29 Fgfrl1
 fibroblast growth factor receptor-like 1
 418
 0.74
chr3_88621762_88621937 0.29 Arhgef2
 rho/rac guanine nucleotide exchange factor (GEF) 2
 294
 0.7
chr3_135854687_135854847 0.28 Gm43429
 predicted gene 43429
 5581
 0.15
chr8_123982695_123983176 0.28 Abcb10
 ATP-binding cassette, sub-family B (MDR/TAP), member 10
 187
 0.9
chr4_156197388_156197813 0.27 Agrn
 agrin
 112
 0.92
chr9_63757921_63758461 0.27 Smad3
 SMAD family member 3
 197
 0.95
chr18_74805142_74805295 0.27 Acaa2
 acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)
 11835
 0.15
chr17_46131074_46131225 0.27 Rsph9
 radial spoke head 9 homolog (Chlamydomonas)
 5646
 0.11
chr3_90265438_90266011 0.27 Dennd4b
 DENN/MADD domain containing 4B
 539
 0.55
chr8_69867698_69867908 0.27 Pbx4
 pre B cell leukemia homeobox 4
 1518
 0.25
chr7_98815262_98816052 0.26 Wnt11
 wingless-type MMTV integration site family, member 11
 19455
 0.15
chr7_112953811_112954004 0.26 Rassf10
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
 55
 0.98
chr10_118141645_118141959 0.26 Mdm1
 transformed mouse 3T3 cell double minute 1
 9
 0.97
chr5_142678131_142678282 0.26 Slc29a4
 solute carrier family 29 (nucleoside transporters), member 4
 14306
 0.16
chr6_145865476_145865643 0.26 Bhlhe41
 basic helix-loop-helix family, member e41
 1
 0.97
chr4_133753896_133754062 0.26 Arid1a
 AT rich interactive domain 1A (SWI-like)
 3
 0.97
chr10_128918325_128918482 0.26 Rdh5
 retinol dehydrogenase 5
 302
 0.78
chr8_111729657_111729830 0.26 Bcar1
 breast cancer anti-estrogen resistance 1
 2362
 0.27
chr2_78868942_78869388 0.26 Ube2e3
 ubiquitin-conjugating enzyme E2E 3
 75
 0.98
chr15_25622272_25622843 0.26 Myo10
 myosin X
 8
 0.98
chr15_35155344_35155973 0.26 Stk3
 serine/threonine kinase 3
 11
 0.98
chr17_5958348_5958506 0.26 Synj2
 synaptojanin 2
 17024
 0.17
chr19_55120958_55121109 0.26 Gpam
 glycerol-3-phosphate acyltransferase, mitochondrial
 6170
 0.21
chr12_86498924_86499075 0.26 Esrrb
 estrogen related receptor, beta
 5410
 0.28
chr2_154790667_154791197 0.26 Raly
 hnRNP-associated with lethal yellow
 164
 0.79
chr18_39362507_39362658 0.25 Arhgap26
 Rho GTPase activating protein 26
 1
 0.98
chr2_148045849_148046021 0.25 Foxa2
 forkhead box A2
 13
 0.97
chr9_35045000_35045333 0.25 St3gal4
 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
 10628
 0.18
chr13_24802074_24802420 0.25 BC005537
 cDNA sequence BC005537
 227
 0.89
chr8_31525478_31525629 0.25 Gm45303
 predicted gene 45303
 33577
 0.2
chr16_59639807_59639972 0.25 Arl6
 ADP-ribosylation factor-like 6
 498
 0.57
chr7_80993275_80993641 0.25 Gm44899
 predicted gene 44899
 43
 0.72
chr10_81416920_81417099 0.25 Mir1191b
 microRNA 1191b
 712
 0.37
chr18_56707488_56708012 0.25 Lmnb1
 lamin B1
 63
 0.97
chr6_71271410_71271731 0.25 Mir8112
 microRNA 8112
 101
 0.49
chr1_93214373_93214535 0.25 Sned1
 sushi, nidogen and EGF-like domains 1
 21387
 0.12
chr17_15381768_15382106 0.24 Dll1
 delta like canonical Notch ligand 1
 5065
 0.17
chr14_62177648_62177815 0.24 Gm35419
 predicted gene, 35419
 6605
 0.23
chr5_107986937_107987463 0.24 Dipk1a
 divergent protein kinase domain 1A
 115
 0.95
chr11_19925489_19925868 0.24 Spred2
 sprouty-related EVH1 domain containing 2
 1236
 0.59
chr4_62999426_62999588 0.24 Zfp618
 zinc finger protein 618
 33933
 0.15
chr4_101647476_101647833 0.24 Leprot
 leptin receptor overlapping transcript
 64
 0.98
chr4_141324590_141325156 0.24 Epha2
 Eph receptor A2
 7960
 0.1
chr13_62879517_62879679 0.24 Fbp1
 fructose bisphosphatase 1
 6840
 0.14
chr11_90249449_90249792 0.24 Mmd
 monocyte to macrophage differentiation-associated
 144
 0.97
chr2_25983198_25983706 0.24 Camsap1
 calmodulin regulated spectrin-associated protein 1
 170
 0.93
chr17_6742196_6742355 0.24 Ezr
 ezrin
 546
 0.75
chr15_7201350_7201501 0.24 Egflam
 EGF-like, fibronectin type III and laminin G domains
 21644
 0.23
chr1_192137129_192137636 0.24 Gm10516
 predicted gene 10516
 37
 0.76
chr15_77929026_77929198 0.24 Txn2
 thioredoxin 2
 106
 0.96
chr8_88122421_88122584 0.23 Cnep1r1
 CTD nuclear envelope phosphatase 1 regulatory subunit 1
 3695
 0.15
chr9_14275987_14276328 0.23 Sesn3
 sestrin 3
 144
 0.95
chr11_120804472_120804662 0.23 Fasn
 fatty acid synthase
 4038
 0.1
chr19_10065348_10065653 0.23 Fads2
 fatty acid desaturase 2
 5687
 0.14
chr2_165826093_165826253 0.23 Zmynd8
 zinc finger, MYND-type containing 8
 25949
 0.14
chr19_44401904_44402310 0.23 Scd1
 stearoyl-Coenzyme A desaturase 1
 4583
 0.17
chr13_107021812_107022148 0.23 Kif2a
 kinesin family member 2A
 47
 0.9
chr3_89378414_89378785 0.23 Zbtb7b
 zinc finger and BTB domain containing 7B
 8590
 0.06
chr17_35866032_35866679 0.23 Ppp1r18
 protein phosphatase 1, regulatory subunit 18
 260
 0.6
chr4_53203800_53203965 0.23 4930412L05Rik
 RIKEN cDNA 4930412L05 gene
 13679
 0.18
chr15_99772368_99772764 0.22 Cers5
 ceramide synthase 5
 35
 0.94
chr11_100388061_100388239 0.22 Jup
 junction plakoglobin
 1380
 0.21
chr14_25460512_25460899 0.22 Zmiz1os1
 Zmiz1 opposite strand 1
 423
 0.57
chr9_45042346_45042523 0.22 Mpzl2
 myelin protein zero-like 2
 9
 0.95
chr8_84647459_84647654 0.22 Cacna1a
 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
 8565
 0.11
chr10_85102143_85102819 0.22 Fhl4
 four and a half LIM domains 4
 14
 0.65
chr3_146614890_146615260 0.22 Dnase2b
 deoxyribonuclease II beta
 521
 0.7
chr4_125084927_125085557 0.22 Meaf6
 MYST/Esa1-associated factor 6
 19
 0.8
chr9_107649565_107649816 0.22 Slc38a3
 solute carrier family 38, member 3
 6330
 0.08
chr11_55077358_55077552 0.22 Ccdc69
 coiled-coil domain containing 69
 652
 0.62
chr7_67634879_67635046 0.22 Gm45100
 predicted gene 45100
 2803
 0.19
chr4_133197958_133198109 0.22 Mir7017
 microRNA 7017
 2378
 0.19
chr9_106453538_106453842 0.22 Pcbp4
 poly(rC) binding protein 4
 152
 0.83
chr9_8003649_8004083 0.22 Yap1
 yes-associated protein 1
 91
 0.94
chr19_46484470_46484829 0.22 Sufu
 SUFU negative regulator of hedgehog signaling
 1552
 0.33
chr13_73320140_73320291 0.22 Gm10263
 predicted gene 10263
 2371
 0.22
chr15_81523743_81523926 0.22 Gm5218
 predicted gene 5218
 24289
 0.11
chr18_53266456_53266641 0.21 Snx24
 sorting nexing 24
 20779
 0.21
chr4_82513106_82513454 0.21 Gm11266
 predicted gene 11266
 5264
 0.22
chr2_160715771_160715932 0.21 Top1
 topoisomerase (DNA) I
 1618
 0.36
chr18_38938372_38938544 0.21 Fgf1
 fibroblast growth factor 1
 8986
 0.19
chr18_80704875_80705052 0.21 Gm50211
 predicted gene, 50211
 227
 0.92
chr1_153332770_153333177 0.21 Lamc1
 laminin, gamma 1
 187
 0.94
chr11_102316988_102317304 0.21 Ubtf
 upstream binding transcription factor, RNA polymerase I
 141
 0.92
chr15_76461284_76461460 0.21 Scx
 scleraxis
 3852
 0.1
chr15_78845338_78845568 0.21 Cdc42ep1
 CDC42 effector protein (Rho GTPase binding) 1
 2829
 0.13
chr8_122324060_122324293 0.21 Zfpm1
 zinc finger protein, multitype 1
 9522
 0.13
chr3_123508261_123508839 0.21 Snhg8
 small nucleolar RNA host gene 8
 146
 0.8
chr5_53213263_53213555 0.21 Sel1l3
 sel-1 suppressor of lin-12-like 3 (C. elegans)
 43
 0.98
chr2_165969012_165969173 0.21 Gm11462
 predicted gene 11462
 9303
 0.13
chr2_173218906_173219070 0.21 Zbp1
 Z-DNA binding protein 1
 65
 0.97
chr19_8757228_8757608 0.21 Nxf1
 nuclear RNA export factor 1
 268
 0.68
chr15_78928152_78928339 0.21 Lgals1
 lectin, galactose binding, soluble 1
 1519
 0.18
chr8_83742379_83742550 0.21 Adgre5
 adhesion G protein-coupled receptor E5
 1138
 0.36
chr13_59615637_59615804 0.21 Naa35
 N(alpha)-acetyltransferase 35, NatC auxiliary subunit
 2191
 0.21
chr7_75848190_75848358 0.21 Klhl25
 kelch-like 25
 36
 0.98
chr4_152086599_152087188 0.20 Plekhg5
 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
 35
 0.96
chr6_82041430_82042014 0.20 Eva1a
 eva-1 homolog A (C. elegans)
 34
 0.97
chr15_10211526_10211677 0.20 Prlr
 prolactin receptor
 1864
 0.47
chr2_32451966_32452185 0.20 Slc25a25
 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
 630
 0.52
chr8_35654772_35654964 0.20 Mfhas1
 malignant fibrous histiocytoma amplified sequence 1
 47591
 0.11
chr9_94696793_94696976 0.20 Gm16262
 predicted gene 16262
 5435
 0.19
chr12_54862458_54862874 0.20 1700081N11Rik
 RIKEN cDNA 1700081N11 gene
 19
 0.51
chr17_56123743_56124087 0.20 Lrg1
 leucine-rich alpha-2-glycoprotein 1
 1914
 0.16
chr6_73251429_73251599 0.20 Suclg1
 succinate-CoA ligase, GDP-forming, alpha subunit
 2846
 0.25
chr11_72265561_72265712 0.20 1700051A21Rik
 RIKEN cDNA 1700051A21 gene
 785
 0.37
chr3_97275847_97276077 0.20 Gm43073
 predicted gene 43073
 898
 0.56

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.1 0.5 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.5 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.4 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 0.9 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 0.6 GO:0021764 amygdala development(GO:0021764)
0.1 0.2 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1 0.3 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.3 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.1 0.3 GO:0031627 telomeric loop formation(GO:0031627)
0.1 0.2 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 0.2 GO:1902075 cellular response to salt(GO:1902075)
0.1 0.3 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.2 GO:0032910 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.1 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.3 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.3 GO:1903276 regulation of sodium ion export(GO:1903273) regulation of sodium ion export from cell(GO:1903276)
0.1 0.4 GO:0001842 neural fold formation(GO:0001842)
0.1 0.2 GO:0072131 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.1 0.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.1 GO:0006808 regulation of nitrogen utilization(GO:0006808)
0.1 0.3 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.2 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.2 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0061144 alveolar secondary septum development(GO:0061144)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.2 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.1 GO:1903660 regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.2 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.3 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.3 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.2 GO:0071225 cellular response to muramyl dipeptide(GO:0071225)
0.0 0.1 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0000087 mitotic M phase(GO:0000087)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.1 GO:0021648 vestibulocochlear nerve morphogenesis(GO:0021648)
0.0 0.1 GO:0003166 bundle of His development(GO:0003166)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.1 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.4 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031)
0.0 0.3 GO:1902033 regulation of hematopoietic stem cell proliferation(GO:1902033)
0.0 0.3 GO:0060068 vagina development(GO:0060068)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.1 GO:0001834 trophectodermal cell proliferation(GO:0001834)
0.0 0.2 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.3 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.1 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.2 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.0 GO:0021590 cerebellum maturation(GO:0021590)
0.0 0.1 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.2 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0061550 cranial ganglion development(GO:0061550)
0.0 0.3 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.7 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.0 GO:1903726 negative regulation of phospholipid biosynthetic process(GO:0071072) negative regulation of phospholipid metabolic process(GO:1903726)
0.0 0.1 GO:0046083 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.3 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.0 0.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.1 GO:0061010 gall bladder development(GO:0061010)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0018992 germ-line sex determination(GO:0018992)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0003348 cardiac endothelial cell differentiation(GO:0003348)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.0 GO:0060948 cardiac vascular smooth muscle cell development(GO:0060948)
0.0 0.0 GO:0002424 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0 0.1 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 1.0 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.1 GO:0042097 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402)
0.0 0.1 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 0.1 GO:2000591 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0 0.2 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.0 0.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:0061156 pulmonary artery morphogenesis(GO:0061156)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.1 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.1 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.0 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:0090188 negative regulation of pancreatic juice secretion(GO:0090188)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.2 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.0 GO:0060681 ureteric bud elongation(GO:0060677) branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402) Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.0 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.2 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.0 GO:0090230 regulation of centromere complex assembly(GO:0090230)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0 0.1 GO:0071139 resolution of recombination intermediates(GO:0071139)
0.0 0.1 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.1 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.0 0.1 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.0 GO:0000436 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991) positive regulation of transcription by glucose(GO:0046016)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.1 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.0 GO:0038027 apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0015879 carnitine transport(GO:0015879)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.1 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.0 0.1 GO:0035459 cargo loading into vesicle(GO:0035459)
0.0 0.1 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.0 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
0.0 0.0 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.1 GO:0030836 positive regulation of actin filament depolymerization(GO:0030836)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.0 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
0.0 0.0 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.0 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.0 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.0 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.0 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:0006848 pyruvate transport(GO:0006848)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.1 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0 0.1 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.0 GO:0048320 axial mesoderm morphogenesis(GO:0048319) axial mesoderm formation(GO:0048320)
0.0 0.0 GO:0006222 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.2 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 0.0 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.1 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.1 GO:0035729 response to hepatocyte growth factor(GO:0035728) cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.3 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.0 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.0 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.0 GO:0046078 dUMP metabolic process(GO:0046078)
0.0 0.1 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.0 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.1 GO:0042436 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0 0.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.0 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.1 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.0 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:0009756 carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.0 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.0 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.0 GO:0045764 positive regulation of cellular amino acid metabolic process(GO:0045764)
0.0 0.1 GO:0017014 protein nitrosylation(GO:0017014)
0.0 0.1 GO:0002488 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591)
0.0 0.1 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:1901026 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0 0.0 GO:1990144 intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
0.0 0.0 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0 0.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.0 GO:0018904 ether metabolic process(GO:0018904)
0.0 0.2 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.0 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 0.0 GO:0010288 response to lead ion(GO:0010288)
0.0 0.0 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.0 GO:0019042 viral latency(GO:0019042)
0.0 0.1 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.0 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.0 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.1 GO:0060746 parental behavior(GO:0060746)
0.0 0.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.0 GO:1902965 protein localization to early endosome(GO:1902946) regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 0.4 GO:0006414 translational elongation(GO:0006414)
0.0 0.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.1 GO:0019359 nicotinamide nucleotide biosynthetic process(GO:0019359)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.4 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.0 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.2 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.0 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.0 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0070847 core mediator complex(GO:0070847)
0.1 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.7 GO:0031010 ISWI-type complex(GO:0031010)
0.1 0.2 GO:0043259 laminin-10 complex(GO:0043259)
0.1 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.2 GO:0044393 microspike(GO:0044393)
0.1 0.2 GO:0032127 dense core granule membrane(GO:0032127)
0.1 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:1903349 omegasome membrane(GO:1903349)
0.0 0.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0036396 MIS complex(GO:0036396)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.0 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0005605 basal lamina(GO:0005605)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.0 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.0 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.0 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.3 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.4 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.4 GO:0043426 MRF binding(GO:0043426)
0.1 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.2 GO:0032551 UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.2 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.3 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.2 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0015186 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.2 GO:0045340 mercury ion binding(GO:0045340)
0.0 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.5 GO:0048038 quinone binding(GO:0048038)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.1 GO:0030519 snoRNP binding(GO:0030519)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.0 0.1 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0016215 acyl-CoA desaturase activity(GO:0016215)
0.0 0.3 GO:0036222 XTP diphosphatase activity(GO:0036222)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.0 GO:0032557 pyrimidine ribonucleotide binding(GO:0032557)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.0 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.0 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.0 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.0 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.0 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.0 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.0 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.0 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.0 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0070402 NADPH binding(GO:0070402)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.0 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.0 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.0 0.0 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0019002 GMP binding(GO:0019002)
0.0 0.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.0 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.1 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.1 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.0 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.0 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.3 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.1 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.1 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.5 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha