Project

ENCSR904DTN: DNase-seq of mouse liver in constant darkness

Navigation

Downloads

CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for E2f6

Z-value: 1.76

Motif logo

Transcription factors associated with E2f6

Gene Symbol	Gene ID	Gene Info
E2f6 Ensembl NCBI MGI UniProt	ENSMUSG00000057469.7	E2f6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
E2f6	chr12_16810873_16811068	1	0.968976	-0.95	4.1e-03	Click!
E2f6	chr12_16811105_16811267	22	0.968365	-0.83	4.3e-02	Click!
E2f6	chr12_16811292_16811447	205	0.916756	-0.72	1.1e-01	Click!
E2f6	chr12_16836304_16836455	12228	0.137491	0.42	4.1e-01	Click!
E2f6	chr12_16828657_16829045	4700	0.162460	-0.07	9.0e-01	Click!

Activity of the E2f6 motif across conditions

Conditions sorted by the z-value of the E2f6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr19_29806024_29806429	1.25	9930021J03Rik	RIKEN cDNA 9930021J03 gene	237	0.69
chrY_90784776_90785079	1.01	Gm47283	predicted gene, 47283	16	0.98
chr3_37419572_37419987	0.96	Spata5	spermatogenesis associated 5	117	0.59
chr15_102470710_102471029	0.93	Pcbp2	poly(rC) binding protein 2	84	0.94
chr1_37864873_37865372	0.89	Tsga10	testis specific 10	43	0.67
chrX_170009846_170010189	0.84	Erdr1	erythroid differentiation regulator 1	22	0.97
chr9_44709221_44709515	0.84	Phldb1	pleckstrin homology like domain, family B, member 1	941	0.33
chr12_110381296_110381622	0.74	Gm47195	predicted gene, 47195	56074	0.08
chr7_127026907_127027653	0.70	Maz	MYC-associated zinc finger protein (purine-binding transcription factor)	243	0.69
chr6_17636992_17637388	0.70	Capza2	capping protein (actin filament) muscle Z-line, alpha 2	77	0.97
chrX_12761746_12762400	0.70	Med14	mediator complex subunit 14	0	0.73
chr14_31217734_31217896	0.69	Sema3g	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G	45	0.92
chr11_120378223_120379003	0.60	Faap100	Fanconi anemia core complex associated protein 100	96	0.92
chr12_25140626_25140792	0.59	Gm36287	predicted gene, 36287	10206	0.16
chr5_129941480_129942081	0.58	Vkorc1l1	vitamin K epoxide reductase complex, subunit 1-like 1	190	0.89
chr3_89090782_89091135	0.56	Rusc1	RUN and SH3 domain containing 1	913	0.34
chr11_53818731_53818912	0.54	Gm12216	predicted gene 12216	22946	0.11
chr7_44815923_44816372	0.54	Nup62	nucleoporin 62	59	0.66
chr9_98424555_98424727	0.54	Rbp1	retinol binding protein 1, cellular	1680	0.4
chr14_25378261_25378665	0.54	Gm26660	predicted gene, 26660	172	0.96
chr9_107657905_107658551	0.52	Slc38a3	solute carrier family 38, member 3	967	0.31
chr13_24316648_24316847	0.50	Gm23340	predicted gene, 23340	105	0.94
chr6_147638472_147638628	0.48	1700049E15Rik	RIKEN cDNA 1700049E15 gene	51691	0.14
chr18_65989569_65989860	0.48	Lman1	lectin, mannose-binding, 1	3946	0.15
chr6_120665412_120665778	0.48	Cecr2	CECR2, histone acetyl-lysine reader	774	0.66
chr4_59549239_59549668	0.47	Ptbp3	polypyrimidine tract binding protein 3	89	0.76
chr11_119052774_119052944	0.47	Cbx8	chromobox 8	11890	0.15
chr11_58199124_58199368	0.47	Igtp	interferon gamma induced GTPase	310	0.51
chr5_138857853_138858235	0.46	Gm5294	predicted gene 5294	37964	0.15
chrX_42068446_42068784	0.46	Xiap	X-linked inhibitor of apoptosis	140	0.97
chr15_102098310_102098461	0.44	Tns2	tensin 2	2028	0.2
chr15_98732323_98732512	0.43	Fkbp11	FK506 binding protein 11	4219	0.11
chr10_126900802_126900994	0.42	Atp23	ATP23 metallopeptidase and ATP synthase assembly factor homolog	450	0.74
chrX_162888665_162888826	0.42	Syap1	synapse associated protein 1	298	0.83
chr8_74993902_74994396	0.41	Hmgxb4	HMG box domain containing 4	437	0.82
chr5_86172358_86172795	0.41	Uba6	ubiquitin-like modifier activating enzyme 6	65	0.97
chr7_31008253_31008404	0.41	Fam187b	family with sequence similarity 187, member B	26458	0.06
chr11_90418039_90418197	0.41	Hlf	hepatic leukemia factor	27223	0.21
chr15_79690269_79690868	0.41	Gtpbp1	GTP binding protein 1	277	0.78
chr4_57916402_57916601	0.40	D630039A03Rik	RIKEN cDNA D630039A03 gene	204	0.94
chr11_97798801_97799320	0.40	Lasp1	LIM and SH3 protein 1	60	0.94
chrX_94234532_94234995	0.39	Klhl15	kelch-like 15	159	0.94
chr11_16817302_16817617	0.39	Egfros	epidermal growth factor receptor, opposite strand	13243	0.21
chr6_67267595_67268050	0.38	Serbp1	serpine1 mRNA binding protein 1	492	0.74
chr11_120814677_120814902	0.38	Fasn	fatty acid synthase	666	0.5
chr13_36736119_36736534	0.38	Nrn1	neuritin 1	1195	0.44
chr10_108161776_108162265	0.38	Ppp1r12a	protein phosphatase 1, regulatory subunit 12A	173	0.96
chr8_105170716_105171167	0.38	Cbfb	core binding factor beta	4	0.94
chr1_151500754_151501127	0.37	Rnf2	ring finger protein 2	15	0.95
chr9_51008973_51009376	0.37	Sik2	salt inducible kinase 2	101	0.97
chr2_68873804_68874167	0.36	Cers6	ceramide synthase 6	12399	0.14
chr5_22344788_22344947	0.36	Reln	reelin	165	0.94
chr11_70653511_70654114	0.36	Pfn1	profilin 1	786	0.31
chr8_91706641_91706804	0.35	Gm36325	predicted gene, 36325	7691	0.14
chr19_41482156_41482948	0.35	Lcor	ligand dependent nuclear receptor corepressor	85	0.98
chr9_59036274_59036848	0.35	Neo1	neogenin	120	0.98
chr3_107256063_107256233	0.34	Prok1	prokineticin 1	16441	0.12
chr18_76301148_76301315	0.34	Gm50360	predicted gene, 50360	20593	0.19
chr7_36697808_36698005	0.34	Tshz3	teashirt zinc finger family member 3	212	0.9
chr6_99734849_99735003	0.34	Prok2	prokineticin 2	8534	0.15
chr13_23551584_23551775	0.33	H4c6	H4 clustered histone 6	31	0.89
chr12_102757157_102757358	0.33	Gm28051	predicted gene, 28051	508	0.32
chr5_113148745_113149067	0.33	Gm42161	predicted gene, 42161	3578	0.14
chr2_25698782_25698956	0.33	Obp2a	odorant binding protein 2A	1174	0.24
chr15_27487150_27487338	0.33	Tiaf2	TGF-beta1-induced anti-apoptotic factor 2	8238	0.16
chr7_28957656_28957827	0.33	Actn4	actinin alpha 4	4482	0.12
chr6_146155065_146155230	0.32	Itpr2	inositol 1,4,5-triphosphate receptor 2	7939	0.27
chr9_64340286_64341080	0.32	Dis3l	DIS3 like exosome 3'-5' exoribonuclease	80	0.97
chr3_8753511_8753662	0.32	Gm37647	predicted gene, 37647	6762	0.19
chr10_53378945_53379463	0.32	Gm47641	predicted gene, 47641	248	0.79
chr10_81524333_81524508	0.32	Gna15	guanine nucleotide binding protein, alpha 15	195	0.8
chr5_135573104_135573267	0.32	Ccl24	chemokine (C-C motif) ligand 24	136	0.94
chr10_86923470_86923734	0.32	Gm16270	predicted gene 16270	14123	0.13
chr8_109737291_109737613	0.32	Atxn1l	ataxin 1-like	270	0.89
chr1_190169557_190169709	0.32	Prox1	prospero homeobox 1	234	0.76
chr2_79254950_79255348	0.32	Itga4	integrin alpha 4	277	0.94
chr4_133967208_133967543	0.31	Hmgn2	high mobility group nucleosomal binding domain 2	66	0.96
chr7_31128675_31128826	0.31	Scn1b	sodium channel, voltage-gated, type I, beta	1747	0.19
chr12_118301006_118301192	0.31	Sp4	trans-acting transcription factor 4	269	0.95
chr2_121427610_121427761	0.31	Pdia3	protein disulfide isomerase associated 3	3055	0.1
chr15_38299429_38299762	0.31	Klf10	Kruppel-like factor 10	200	0.91
chr15_59012963_59013142	0.31	Mtss1	MTSS I-BAR domain containing 1	27544	0.15
chr5_144255609_144256174	0.31	2900089D17Rik	RIKEN cDNA 2900089D17 gene	295	0.71
chr13_74121256_74121414	0.31	Slc9a3	solute carrier family 9 (sodium/hydrogen exchanger), member 3	122	0.96
chr11_5906116_5906267	0.31	Gck	glucokinase	4104	0.13
chr17_45882790_45882986	0.30	4930542M03Rik	RIKEN cDNA 4930542M03 gene	1436	0.35
chr2_128698686_128698859	0.30	Mertk	MER proto-oncogene tyrosine kinase	184	0.94
chr8_107096349_107096693	0.29	Terf2	telomeric repeat binding factor 2	7	0.86
chr10_18368209_18368416	0.29	Nhsl1	NHS-like 1	22010	0.18
chr13_9764358_9764721	0.29	Zmynd11	zinc finger, MYND domain containing 11	51	0.97
chr17_80728516_80728734	0.29	Map4k3	mitogen-activated protein kinase kinase kinase kinase 3	140	0.84
chr3_130410150_130410482	0.29	Col25a1	collagen, type XXV, alpha 1	68500	0.11
chr8_95357230_95357503	0.29	Mmp15	matrix metallopeptidase 15	5098	0.14
chr5_108694583_108695258	0.29	Fgfrl1	fibroblast growth factor receptor-like 1	418	0.74
chr3_88621762_88621937	0.29	Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2	294	0.7
chr3_135854687_135854847	0.28	Gm43429	predicted gene 43429	5581	0.15
chr8_123982695_123983176	0.28	Abcb10	ATP-binding cassette, sub-family B (MDR/TAP), member 10	187	0.9
chr4_156197388_156197813	0.27	Agrn	agrin	112	0.92
chr9_63757921_63758461	0.27	Smad3	SMAD family member 3	197	0.95
chr18_74805142_74805295	0.27	Acaa2	acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)	11835	0.15
chr17_46131074_46131225	0.27	Rsph9	radial spoke head 9 homolog (Chlamydomonas)	5646	0.11
chr3_90265438_90266011	0.27	Dennd4b	DENN/MADD domain containing 4B	539	0.55
chr8_69867698_69867908	0.27	Pbx4	pre B cell leukemia homeobox 4	1518	0.25
chr7_98815262_98816052	0.26	Wnt11	wingless-type MMTV integration site family, member 11	19455	0.15
chr7_112953811_112954004	0.26	Rassf10	Ras association (RalGDS/AF-6) domain family (N-terminal) member 10	55	0.98
chr10_118141645_118141959	0.26	Mdm1	transformed mouse 3T3 cell double minute 1	9	0.97
chr5_142678131_142678282	0.26	Slc29a4	solute carrier family 29 (nucleoside transporters), member 4	14306	0.16
chr6_145865476_145865643	0.26	Bhlhe41	basic helix-loop-helix family, member e41	1	0.97
chr4_133753896_133754062	0.26	Arid1a	AT rich interactive domain 1A (SWI-like)	3	0.97
chr10_128918325_128918482	0.26	Rdh5	retinol dehydrogenase 5	302	0.78
chr8_111729657_111729830	0.26	Bcar1	breast cancer anti-estrogen resistance 1	2362	0.27
chr2_78868942_78869388	0.26	Ube2e3	ubiquitin-conjugating enzyme E2E 3	75	0.98
chr15_25622272_25622843	0.26	Myo10	myosin X	8	0.98
chr15_35155344_35155973	0.26	Stk3	serine/threonine kinase 3	11	0.98
chr17_5958348_5958506	0.26	Synj2	synaptojanin 2	17024	0.17
chr19_55120958_55121109	0.26	Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	6170	0.21
chr12_86498924_86499075	0.26	Esrrb	estrogen related receptor, beta	5410	0.28
chr2_154790667_154791197	0.26	Raly	hnRNP-associated with lethal yellow	164	0.79
chr18_39362507_39362658	0.25	Arhgap26	Rho GTPase activating protein 26	1	0.98
chr2_148045849_148046021	0.25	Foxa2	forkhead box A2	13	0.97
chr9_35045000_35045333	0.25	St3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	10628	0.18
chr13_24802074_24802420	0.25	BC005537	cDNA sequence BC005537	227	0.89
chr8_31525478_31525629	0.25	Gm45303	predicted gene 45303	33577	0.2
chr16_59639807_59639972	0.25	Arl6	ADP-ribosylation factor-like 6	498	0.57
chr7_80993275_80993641	0.25	Gm44899	predicted gene 44899	43	0.72
chr10_81416920_81417099	0.25	Mir1191b	microRNA 1191b	712	0.37
chr18_56707488_56708012	0.25	Lmnb1	lamin B1	63	0.97
chr6_71271410_71271731	0.25	Mir8112	microRNA 8112	101	0.49
chr1_93214373_93214535	0.25	Sned1	sushi, nidogen and EGF-like domains 1	21387	0.12
chr17_15381768_15382106	0.24	Dll1	delta like canonical Notch ligand 1	5065	0.17
chr14_62177648_62177815	0.24	Gm35419	predicted gene, 35419	6605	0.23
chr5_107986937_107987463	0.24	Dipk1a	divergent protein kinase domain 1A	115	0.95
chr11_19925489_19925868	0.24	Spred2	sprouty-related EVH1 domain containing 2	1236	0.59
chr4_62999426_62999588	0.24	Zfp618	zinc finger protein 618	33933	0.15
chr4_101647476_101647833	0.24	Leprot	leptin receptor overlapping transcript	64	0.98
chr4_141324590_141325156	0.24	Epha2	Eph receptor A2	7960	0.1
chr13_62879517_62879679	0.24	Fbp1	fructose bisphosphatase 1	6840	0.14
chr11_90249449_90249792	0.24	Mmd	monocyte to macrophage differentiation-associated	144	0.97
chr2_25983198_25983706	0.24	Camsap1	calmodulin regulated spectrin-associated protein 1	170	0.93
chr17_6742196_6742355	0.24	Ezr	ezrin	546	0.75
chr15_7201350_7201501	0.24	Egflam	EGF-like, fibronectin type III and laminin G domains	21644	0.23
chr1_192137129_192137636	0.24	Gm10516	predicted gene 10516	37	0.76
chr15_77929026_77929198	0.24	Txn2	thioredoxin 2	106	0.96
chr8_88122421_88122584	0.23	Cnep1r1	CTD nuclear envelope phosphatase 1 regulatory subunit 1	3695	0.15
chr9_14275987_14276328	0.23	Sesn3	sestrin 3	144	0.95
chr11_120804472_120804662	0.23	Fasn	fatty acid synthase	4038	0.1
chr19_10065348_10065653	0.23	Fads2	fatty acid desaturase 2	5687	0.14
chr2_165826093_165826253	0.23	Zmynd8	zinc finger, MYND-type containing 8	25949	0.14
chr19_44401904_44402310	0.23	Scd1	stearoyl-Coenzyme A desaturase 1	4583	0.17
chr13_107021812_107022148	0.23	Kif2a	kinesin family member 2A	47	0.9
chr3_89378414_89378785	0.23	Zbtb7b	zinc finger and BTB domain containing 7B	8590	0.06
chr17_35866032_35866679	0.23	Ppp1r18	protein phosphatase 1, regulatory subunit 18	260	0.6
chr4_53203800_53203965	0.23	4930412L05Rik	RIKEN cDNA 4930412L05 gene	13679	0.18
chr15_99772368_99772764	0.22	Cers5	ceramide synthase 5	35	0.94
chr11_100388061_100388239	0.22	Jup	junction plakoglobin	1380	0.21
chr14_25460512_25460899	0.22	Zmiz1os1	Zmiz1 opposite strand 1	423	0.57
chr9_45042346_45042523	0.22	Mpzl2	myelin protein zero-like 2	9	0.95
chr8_84647459_84647654	0.22	Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	8565	0.11
chr10_85102143_85102819	0.22	Fhl4	four and a half LIM domains 4	14	0.65
chr3_146614890_146615260	0.22	Dnase2b	deoxyribonuclease II beta	521	0.7
chr4_125084927_125085557	0.22	Meaf6	MYST/Esa1-associated factor 6	19	0.8
chr9_107649565_107649816	0.22	Slc38a3	solute carrier family 38, member 3	6330	0.08
chr11_55077358_55077552	0.22	Ccdc69	coiled-coil domain containing 69	652	0.62
chr7_67634879_67635046	0.22	Gm45100	predicted gene 45100	2803	0.19
chr4_133197958_133198109	0.22	Mir7017	microRNA 7017	2378	0.19
chr9_106453538_106453842	0.22	Pcbp4	poly(rC) binding protein 4	152	0.83
chr9_8003649_8004083	0.22	Yap1	yes-associated protein 1	91	0.94
chr19_46484470_46484829	0.22	Sufu	SUFU negative regulator of hedgehog signaling	1552	0.33
chr13_73320140_73320291	0.22	Gm10263	predicted gene 10263	2371	0.22
chr15_81523743_81523926	0.22	Gm5218	predicted gene 5218	24289	0.11
chr18_53266456_53266641	0.21	Snx24	sorting nexing 24	20779	0.21
chr4_82513106_82513454	0.21	Gm11266	predicted gene 11266	5264	0.22
chr2_160715771_160715932	0.21	Top1	topoisomerase (DNA) I	1618	0.36
chr18_38938372_38938544	0.21	Fgf1	fibroblast growth factor 1	8986	0.19
chr18_80704875_80705052	0.21	Gm50211	predicted gene, 50211	227	0.92
chr1_153332770_153333177	0.21	Lamc1	laminin, gamma 1	187	0.94
chr11_102316988_102317304	0.21	Ubtf	upstream binding transcription factor, RNA polymerase I	141	0.92
chr15_76461284_76461460	0.21	Scx	scleraxis	3852	0.1
chr15_78845338_78845568	0.21	Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	2829	0.13
chr8_122324060_122324293	0.21	Zfpm1	zinc finger protein, multitype 1	9522	0.13
chr3_123508261_123508839	0.21	Snhg8	small nucleolar RNA host gene 8	146	0.8
chr5_53213263_53213555	0.21	Sel1l3	sel-1 suppressor of lin-12-like 3 (C. elegans)	43	0.98
chr2_165969012_165969173	0.21	Gm11462	predicted gene 11462	9303	0.13
chr2_173218906_173219070	0.21	Zbp1	Z-DNA binding protein 1	65	0.97
chr19_8757228_8757608	0.21	Nxf1	nuclear RNA export factor 1	268	0.68
chr15_78928152_78928339	0.21	Lgals1	lectin, galactose binding, soluble 1	1519	0.18
chr8_83742379_83742550	0.21	Adgre5	adhesion G protein-coupled receptor E5	1138	0.36
chr13_59615637_59615804	0.21	Naa35	N(alpha)-acetyltransferase 35, NatC auxiliary subunit	2191	0.21
chr7_75848190_75848358	0.21	Klhl25	kelch-like 25	36	0.98
chr4_152086599_152087188	0.20	Plekhg5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5	35	0.96
chr6_82041430_82042014	0.20	Eva1a	eva-1 homolog A (C. elegans)	34	0.97
chr15_10211526_10211677	0.20	Prlr	prolactin receptor	1864	0.47
chr2_32451966_32452185	0.20	Slc25a25	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25	630	0.52
chr8_35654772_35654964	0.20	Mfhas1	malignant fibrous histiocytoma amplified sequence 1	47591	0.11
chr9_94696793_94696976	0.20	Gm16262	predicted gene 16262	5435	0.19
chr12_54862458_54862874	0.20	1700081N11Rik	RIKEN cDNA 1700081N11 gene	19	0.51
chr17_56123743_56124087	0.20	Lrg1	leucine-rich alpha-2-glycoprotein 1	1914	0.16
chr6_73251429_73251599	0.20	Suclg1	succinate-CoA ligase, GDP-forming, alpha subunit	2846	0.25
chr11_72265561_72265712	0.20	1700051A21Rik	RIKEN cDNA 1700051A21 gene	785	0.37
chr3_97275847_97276077	0.20	Gm43073	predicted gene 43073	898	0.56

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f6

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.1	0.5	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.1	0.5	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.1	0.4	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.1	0.9	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.1	0.6	GO:0021764	amygdala development(GO:0021764)
0.1	0.2	GO:1901382	chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1	0.3	GO:0009730	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1	0.3	GO:0072194	kidney smooth muscle tissue development(GO:0072194)
0.1	0.3	GO:0031627	telomeric loop formation(GO:0031627)
0.1	0.2	GO:1901674	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1	0.2	GO:1902075	cellular response to salt(GO:1902075)
0.1	0.3	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1	0.3	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.1	0.2	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.1	0.2	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.2	GO:0032910	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.1	0.3	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.1	0.2	GO:0072092	ureteric bud invasion(GO:0072092)
0.1	0.3	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.1	0.2	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1	0.3	GO:1903276	regulation of sodium ion export(GO:1903273) regulation of sodium ion export from cell(GO:1903276)
0.1	0.4	GO:0001842	neural fold formation(GO:0001842)
0.1	0.2	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.1	0.2	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	0.2	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	0.2	GO:1902896	terminal web assembly(GO:1902896)
0.1	0.2	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.1	0.1	GO:0006808	regulation of nitrogen utilization(GO:0006808)
0.1	0.3	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1	0.3	GO:0006776	vitamin A metabolic process(GO:0006776)
0.1	0.2	GO:0071288	cellular response to mercury ion(GO:0071288)
0.1	0.2	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.3	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.1	GO:0061144	alveolar secondary septum development(GO:0061144)
0.0	0.1	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.0	0.1	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.2	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
0.0	0.1	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.1	GO:0042938	dipeptide transport(GO:0042938)
0.0	0.1	GO:1903660	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.7	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.1	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.1	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0	0.2	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0	0.3	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.1	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.3	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0	0.2	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.0	0.2	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
0.0	0.1	GO:0003347	epicardial cell to mesenchymal cell transition(GO:0003347)
0.0	0.1	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.0	0.2	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0000087	mitotic M phase(GO:0000087)
0.0	0.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0003383	apical constriction(GO:0003383)
0.0	0.1	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.0	0.1	GO:0021648	vestibulocochlear nerve morphogenesis(GO:0021648)
0.0	0.1	GO:0003166	bundle of His development(GO:0003166)
0.0	0.1	GO:0046909	intermembrane transport(GO:0046909)
0.0	0.1	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.1	GO:2000383	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0	0.1	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.0	0.1	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.1	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.0	0.4	GO:0040034	regulation of development, heterochronic(GO:0040034)
0.0	0.1	GO:0040031	snRNA modification(GO:0040031)
0.0	0.3	GO:1902033	regulation of hematopoietic stem cell proliferation(GO:1902033)
0.0	0.3	GO:0060068	vagina development(GO:0060068)
0.0	0.1	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	0.1	GO:0001834	trophectodermal cell proliferation(GO:0001834)
0.0	0.2	GO:0072257	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0	0.3	GO:0006662	glycerol ether metabolic process(GO:0006662)
0.0	0.1	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.4	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.3	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.2	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.0	GO:0021590	cerebellum maturation(GO:0021590)
0.0	0.1	GO:0042706	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0	0.2	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.0	0.2	GO:2000015	regulation of determination of dorsal identity(GO:2000015)
0.0	0.1	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.1	GO:0061550	cranial ganglion development(GO:0061550)
0.0	0.3	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	0.7	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0	0.1	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.0	GO:1903726	negative regulation of phospholipid biosynthetic process(GO:0071072) negative regulation of phospholipid metabolic process(GO:1903726)
0.0	0.1	GO:0046083	adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.1	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0	0.3	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.0	0.1	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0	0.1	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.1	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.0	0.1	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.0	0.1	GO:0061010	gall bladder development(GO:0061010)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0018992	germ-line sex determination(GO:0018992)
0.0	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0	0.3	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.2	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.2	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.0	0.1	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.2	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.1	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.0	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.1	GO:0003348	cardiac endothelial cell differentiation(GO:0003348)
0.0	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.0	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
0.0	0.0	GO:0002424	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0	0.1	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	1.0	GO:0035019	somatic stem cell population maintenance(GO:0035019)
0.0	0.1	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.1	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.1	GO:0031508	pericentric heterochromatin assembly(GO:0031508)
0.0	0.1	GO:0042097	interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402)
0.0	0.1	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.1	GO:2000591	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0	0.2	GO:0048680	positive regulation of axon regeneration(GO:0048680)
0.0	0.1	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.0	0.1	GO:0071492	cellular response to UV-A(GO:0071492)
0.0	0.1	GO:0061156	pulmonary artery morphogenesis(GO:0061156)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0	0.1	GO:0045950	negative regulation of mitotic recombination(GO:0045950)
0.0	0.1	GO:0039530	MDA-5 signaling pathway(GO:0039530)
0.0	0.2	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0	0.0	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.2	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.1	GO:0046208	spermine catabolic process(GO:0046208)
0.0	0.3	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.1	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.0	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.1	GO:0090188	negative regulation of pancreatic juice secretion(GO:0090188)
0.0	0.1	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.0	0.1	GO:1903964	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.1	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0	0.2	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0	0.3	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.1	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.0	0.2	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.0	GO:0060681	ureteric bud elongation(GO:0060677) branch elongation involved in ureteric bud branching(GO:0060681)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402) Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0	0.0	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0	0.1	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	0.2	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.1	GO:0035279	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0	0.1	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0046684	response to pyrethroid(GO:0046684)
0.0	0.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.0	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.0	0.1	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.1	GO:0006068	ethanol catabolic process(GO:0006068)
0.0	0.1	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0	0.1	GO:0071139	resolution of recombination intermediates(GO:0071139)
0.0	0.1	GO:0021776	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0	0.1	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0	0.1	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.1	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.0	GO:0000436	carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991) positive regulation of transcription by glucose(GO:0046016)
0.0	0.1	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.1	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.1	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.0	0.1	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.0	GO:0038027	apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.0	0.1	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:0015879	carnitine transport(GO:0015879)
0.0	0.1	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0	0.2	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.0	0.1	GO:2000474	regulation of opioid receptor signaling pathway(GO:2000474)
0.0	0.1	GO:0035459	cargo loading into vesicle(GO:0035459)
0.0	0.1	GO:2000327	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0	0.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.0	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.0	0.1	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
0.0	0.0	GO:0030222	eosinophil differentiation(GO:0030222)
0.0	0.1	GO:0030836	positive regulation of actin filament depolymerization(GO:0030836)
0.0	0.1	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.1	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.2	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.0	GO:1903753	negative regulation of p38MAPK cascade(GO:1903753)
0.0	0.0	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.0	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.1	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.0	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.0	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.0	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.0	GO:0006848	pyruvate transport(GO:0006848)
0.0	0.1	GO:0002159	desmosome assembly(GO:0002159)
0.0	0.1	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.1	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0	0.1	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.0	0.0	GO:0048320	axial mesoderm morphogenesis(GO:0048319) axial mesoderm formation(GO:0048320)
0.0	0.0	GO:0006222	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.3	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.0	0.0	GO:0002572	pro-T cell differentiation(GO:0002572)
0.0	0.1	GO:0061727	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.1	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.1	GO:0035729	response to hepatocyte growth factor(GO:0035728) cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0	0.1	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0	0.3	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.0	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.0	0.0	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.2	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0	0.0	GO:0046078	dUMP metabolic process(GO:0046078)
0.0	0.1	GO:1900273	positive regulation of long-term synaptic potentiation(GO:1900273)
0.0	0.0	GO:0045054	constitutive secretory pathway(GO:0045054)
0.0	0.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.1	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.0	GO:0033686	positive regulation of luteinizing hormone secretion(GO:0033686)
0.0	0.1	GO:0042436	tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0	0.1	GO:0071361	cellular response to ethanol(GO:0071361)
0.0	0.0	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
0.0	0.1	GO:0039694	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0	0.0	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.3	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:0009756	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.2	GO:1903846	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.0	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.0	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.0	0.1	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.0	GO:0045764	positive regulation of cellular amino acid metabolic process(GO:0045764)
0.0	0.1	GO:0017014	protein nitrosylation(GO:0017014)
0.0	0.1	GO:0002488	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:1901026	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0	0.0	GO:1990144	intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
0.0	0.0	GO:0035696	monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0	0.0	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.0	GO:0018904	ether metabolic process(GO:0018904)
0.0	0.2	GO:0042832	defense response to protozoan(GO:0042832)
0.0	0.1	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.0	GO:0002155	regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0	0.0	GO:0010288	response to lead ion(GO:0010288)
0.0	0.0	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.0	GO:0019042	viral latency(GO:0019042)
0.0	0.1	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	0.1	GO:0090383	phagosome acidification(GO:0090383)
0.0	0.0	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0	0.1	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.2	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.0	GO:1902414	protein localization to cell junction(GO:1902414)
0.0	0.1	GO:0060746	parental behavior(GO:0060746)
0.0	0.1	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
0.0	0.0	GO:1902965	protein localization to early endosome(GO:1902946) regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0	0.4	GO:0006414	translational elongation(GO:0006414)
0.0	0.2	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.1	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
0.0	0.1	GO:0019359	nicotinamide nucleotide biosynthetic process(GO:0019359)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.2	GO:0035458	cellular response to interferon-beta(GO:0035458)
0.0	0.0	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.2	GO:0048305	immunoglobulin secretion(GO:0048305)
0.0	0.4	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.0	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.0	0.2	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.0	0.0	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.0	0.0	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0070847	core mediator complex(GO:0070847)
0.1	0.4	GO:0005642	annulate lamellae(GO:0005642)
0.1	0.7	GO:0008290	F-actin capping protein complex(GO:0008290)
0.1	0.3	GO:0071141	SMAD protein complex(GO:0071141)
0.1	0.7	GO:0031010	ISWI-type complex(GO:0031010)
0.1	0.2	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.4	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.1	0.2	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.2	GO:0044393	microspike(GO:0044393)
0.1	0.2	GO:0032127	dense core granule membrane(GO:0032127)
0.1	0.3	GO:0005638	lamin filament(GO:0005638)
0.0	0.6	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.2	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.3	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.6	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.1	GO:1903349	omegasome membrane(GO:1903349)
0.0	0.1	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.2	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)
0.0	0.2	GO:0001652	granular component(GO:0001652)
0.0	0.2	GO:0001650	fibrillar center(GO:0001650)
0.0	0.2	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.2	GO:0045180	basal cortex(GO:0045180)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.1	GO:0036449	microtubule minus-end(GO:0036449)
0.0	0.2	GO:0030430	host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0	0.2	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.1	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.2	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.1	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.2	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0000346	transcription export complex(GO:0000346)
0.0	0.1	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.0	0.2	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0036396	MIS complex(GO:0036396)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.2	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.1	GO:0042583	chromaffin granule(GO:0042583)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.0	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:1990246	uniplex complex(GO:1990246)
0.0	0.1	GO:0043203	axon hillock(GO:0043203)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	0.2	GO:0046930	pore complex(GO:0046930)
0.0	0.8	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.6	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.2	GO:0005605	basal lamina(GO:0005605)
0.0	0.2	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0032437	cuticular plate(GO:0032437)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.0	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.0	0.1	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.2	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.7	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.0	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.0	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.2	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.1	0.5	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.1	0.3	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.1	0.4	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1	0.3	GO:0051425	PTB domain binding(GO:0051425)
0.1	0.2	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.1	0.7	GO:0038191	neuropilin binding(GO:0038191)
0.1	0.2	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1	0.4	GO:0043426	MRF binding(GO:0043426)
0.1	0.2	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.3	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.2	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.2	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.2	GO:0032551	UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.2	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.2	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.3	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.2	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.0	0.1	GO:0048408	epidermal growth factor binding(GO:0048408)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.4	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0015186	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.2	GO:0033142	progesterone receptor binding(GO:0033142)
0.0	0.2	GO:0045340	mercury ion binding(GO:0045340)
0.0	0.3	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.0	0.1	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.5	GO:0048038	quinone binding(GO:0048038)
0.0	0.3	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.1	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.1	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.2	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.2	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.2	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.1	GO:0030519	snoRNP binding(GO:0030519)
0.0	0.1	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.4	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0	0.2	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.0	0.2	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.6	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.2	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.0	0.3	GO:0036222	XTP diphosphatase activity(GO:0036222)
0.0	0.1	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.2	GO:0001164	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.2	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.2	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.3	GO:0019841	retinol binding(GO:0019841)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.1	GO:0045503	dynein light chain binding(GO:0045503)
0.0	0.2	GO:0045322	unmethylated CpG binding(GO:0045322)
0.0	0.1	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:1901612	cardiolipin binding(GO:1901612)
0.0	0.6	GO:0030507	spectrin binding(GO:0030507)
0.0	0.4	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.4	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.1	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.2	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.4	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.2	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.1	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.2	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0019961	interferon binding(GO:0019961)
0.0	0.1	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.0	GO:0032557	pyrimidine ribonucleotide binding(GO:0032557)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.0	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.0	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.0	GO:0048030	disaccharide binding(GO:0048030)
0.0	0.3	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.0	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.0	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.0	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.7	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.0	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.0	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.1	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.0	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.1	GO:0035473	lipase binding(GO:0035473)
0.0	0.1	GO:0071253	connexin binding(GO:0071253)
0.0	0.0	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	0.1	GO:0031779	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.1	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0001055	RNA polymerase II activity(GO:0001055)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.2	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.3	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.0	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.0	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.0	0.0	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.1	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	0.3	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.0	GO:0019002	GMP binding(GO:0019002)
0.0	0.0	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	0.0	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.3	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.1	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.0	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0	0.1	GO:0004673	protein histidine kinase activity(GO:0004673)
0.0	0.1	GO:0019869	chloride channel inhibitor activity(GO:0019869)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.5	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.5	PID REELIN PATHWAY	Reelin signaling pathway
0.4	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.7	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.5	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.5	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.8	PID RHOA PATHWAY	RhoA signaling pathway
0.7	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.2	PID NECTIN PATHWAY	Nectin adhesion pathway
0.5	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.6	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.4	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.3	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.5	PID LKB1 PATHWAY	LKB1 signaling events
0.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.6	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.5	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.3	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.1	SIG CHEMOTAXIS	Genes related to chemotaxis
0.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.3	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	0.6	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.2	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.9	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.1	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.0	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.9	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.8	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.0	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.3	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	0.6	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.6	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.1	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.2	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.2	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.2	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.1	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.1	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.1	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.5	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.2	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.1	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.2	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.1	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.2	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.1	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.1	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha