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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for E2f7

Z-value: 1.17

Motif logo

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Transcription factors associated with E2f7

Gene Symbol Gene ID Gene Info
E2f7
ENSMUSG00000020185.10 E2f7

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

GenePromoterDistanceAssociation probabilityPearson corr. coef.P-valuePlot
E2f7chr10_110706332_110706497390250.1594920.843.7e-02Click!
E2f7chr10_110717608_110717759277560.1901090.758.7e-02Click!
E2f7chr10_110707855_110708037374930.1636880.701.3e-01Click!
E2f7chr10_110727913_110728070174480.2147570.671.5e-01Click!
E2f7chr10_110717138_110717467281370.1891070.661.6e-01Click!

Activity of the E2f7 motif across conditions

Conditions sorted by the z-value of the E2f7 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_40356895_40357462 0.58 Sorbs1
 sorbin and SH3 domain containing 1
 6087
 0.23
chr3_63976545_63977103 0.47 Gmps
 guanine monophosphate synthetase
 718
 0.59
chr14_62506079_62506243 0.38 Gm6076
 predicted gene 6076
 9134
 0.13
chr19_55315497_55315669 0.35 Zdhhc6
 zinc finger, DHHC domain containing 6
 405
 0.66
chr12_12941753_12942056 0.34 Mycn
 v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
 10
 0.97
chr12_104088559_104088873 0.33 Serpina4-ps1
 serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1
 8067
 0.1
chr7_99157033_99157184 0.32 Dgat2
 diacylglycerol O-acyltransferase 2
 12998
 0.12
chr10_3973243_3973628 0.32 Mthfd1l
 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
 291
 0.88
chr6_13654409_13654594 0.28 Bmt2
 base methyltransferase of 25S rRNA 2
 23437
 0.21
chr9_96983440_96983591 0.28 Spsb4
 splA/ryanodine receptor domain and SOCS box containing 4
 680
 0.66
chrX_113185187_113185419 0.28 Chm
 choroidermia (RAB escort protein 1)
 206
 0.95
chr9_102732216_102732808 0.26 Amotl2
 angiomotin-like 2
 1781
 0.24
chr2_156548213_156548364 0.26 Aar2
 AAR2 splicing factor homolog
 664
 0.6
chr4_108425790_108426145 0.25 Gpx7
 glutathione peroxidase 7
 19006
 0.1
chr7_116307697_116308006 0.25 Plekha7
 pleckstrin homology domain containing, family A member 7
 199
 0.91
chr2_12963573_12963747 0.24 Pter
 phosphotriesterase related
 14279
 0.16
chr11_90389300_90389483 0.24 Hlf
 hepatic leukemia factor
 199
 0.96
chr13_107888283_107888446 0.24 Zswim6
 zinc finger SWIM-type containing 6
 1700
 0.45
chr7_44815923_44816372 0.24 Nup62
 nucleoporin 62
 59
 0.66
chrX_12761746_12762400 0.24 Med14
 mediator complex subunit 14
 0
 0.73
chr3_18191923_18192090 0.23 Gm23686
 predicted gene, 23686
 14381
 0.22
chr1_187609763_187609931 0.23 Esrrg
 estrogen-related receptor gamma
 151
 0.97
chr1_84186357_84186508 0.22 Gm18304
 predicted gene, 18304
 18244
 0.2
chr15_96769798_96769949 0.22 Gm8888
 predicted gene 8888
 2795
 0.32
chr14_21088077_21088228 0.22 Adk
 adenosine kinase
 12000
 0.21
chr2_140774319_140774470 0.22 Flrt3
 fibronectin leucine rich transmembrane protein 3
 102925
 0.08
chr5_125525361_125525537 0.22 Tmem132b
 transmembrane protein 132B
 6325
 0.17
chr12_111587380_111587547 0.21 Mark3
 MAP/microtubule affinity regulating kinase 3
 687
 0.55
chr1_190168785_190169209 0.21 Gm28172
 predicted gene 28172
 327
 0.53
chr13_98263629_98263787 0.21 Ankra2
 ankyrin repeat, family A (RFXANK-like), 2
 466
 0.55
chr4_108143871_108144489 0.21 Scp2
 sterol carrier protein 2, liver
 814
 0.57
chr8_13890196_13890558 0.21 Coprs
 coordinator of PRMT5, differentiation stimulator
 96
 0.94
chr7_116039656_116039813 0.21 1110004F10Rik
 RIKEN cDNA 1110004F10 gene
 22
 0.95
chr13_80892174_80892325 0.21 Arrdc3
 arrestin domain containing 3
 1731
 0.32
chr11_77077912_77078299 0.21 Mir423
 microRNA 423
 67
 0.49
chr18_44545771_44545978 0.21 Mcc
 mutated in colorectal cancers
 26358
 0.23
chr2_158865458_158865629 0.20 Dhx35
 DEAH (Asp-Glu-Ala-His) box polypeptide 35
 14914
 0.24
chr11_44519752_44519982 0.20 Rnf145
 ring finger protein 145
 425
 0.83
chr2_11712487_11713017 0.20 Il15ra
 interleukin 15 receptor, alpha chain
 5575
 0.16
chr17_86789278_86789488 0.20 Gm50008
 predicted gene, 50008
 16113
 0.17
chr14_21210943_21211105 0.20 Adk
 adenosine kinase
 107101
 0.06
chrX_140493888_140494053 0.20 Prps1
 phosphoribosyl pyrophosphate synthetase 1
 37357
 0.14
chr11_72945131_72945282 0.20 Gm44467
 predicted gene, 44467
 7901
 0.13
chr17_35866032_35866679 0.19 Ppp1r18
 protein phosphatase 1, regulatory subunit 18
 260
 0.6
chr6_17185802_17185953 0.19 D830026I12Rik
 RIKEN cDNA D830026I12 gene
 11874
 0.2
chr8_110939430_110939581 0.19 St3gal2
 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
 1399
 0.28
chr11_94321337_94321604 0.19 Luc7l3
 LUC7-like 3 (S. cerevisiae)
 425
 0.79
chr14_8326780_8326935 0.19 Fam107a
 family with sequence similarity 107, member A
 8834
 0.19
chr8_104596455_104596703 0.19 Pdp2
 pyruvate dehyrogenase phosphatase catalytic subunit 2
 5128
 0.1
chr6_121308313_121308464 0.19 Slc6a13
 solute carrier family 6 (neurotransmitter transporter, GABA), member 13
 7606
 0.14
chr8_93277574_93277784 0.18 Ces1f
 carboxylesterase 1F
 2048
 0.26
chr6_94687247_94687564 0.18 Lrig1
 leucine-rich repeats and immunoglobulin-like domains 1
 6775
 0.25
chr2_114174645_114174811 0.18 Aqr
 aquarius
 518
 0.79
chr5_129955394_129955708 0.18 Gm43482
 predicted gene 43482
 8815
 0.1
chr11_97689932_97690097 0.18 Pcgf2
 polycomb group ring finger 2
 2393
 0.12
chr15_81871616_81871774 0.18 Phf5a
 PHD finger protein 5A
 30
 0.9
chr11_19925104_19925272 0.18 Spred2
 sprouty-related EVH1 domain containing 2
 746
 0.76
chr19_11912873_11913201 0.18 Patl1
 protein associated with topoisomerase II homolog 1 (yeast)
 594
 0.54
chr11_120231077_120231228 0.17 2900052L18Rik
 RIKEN cDNA 2900052L18 gene
 433
 0.67
chr1_21257119_21257270 0.17 Gsta3
 glutathione S-transferase, alpha 3
 3673
 0.13
chr9_100535718_100535869 0.17 Gm28586
 predicted gene 28586
 4722
 0.16
chr9_21367950_21368210 0.17 Ilf3
 interleukin enhancer binding factor 3
 77
 0.92
chr19_44395706_44395857 0.17 Scd1
 stearoyl-Coenzyme A desaturase 1
 10909
 0.14
chr6_83433566_83433908 0.17 Tet3
 tet methylcytosine dioxygenase 3
 7895
 0.12
chr7_30094964_30095448 0.17 Zfp260
 zinc finger protein 260
 21
 0.94
chr3_129444095_129444246 0.17 Gm5712
 predicted gene 5712
 10497
 0.17
chr2_129101432_129101630 0.17 Polr1b
 polymerase (RNA) I polypeptide B
 504
 0.68
chr16_97763100_97763270 0.17 Ripk4
 receptor-interacting serine-threonine kinase 4
 602
 0.75
chr2_38430021_38430183 0.17 Gm13589
 predicted gene 13589
 6100
 0.16
chr19_21481435_21481596 0.17 Gda
 guanine deaminase
 8070
 0.26
chr5_45450154_45450875 0.17 Qdpr
 quinoid dihydropteridine reductase
 278
 0.86
chr8_40995175_40995326 0.17 Mtus1
 mitochondrial tumor suppressor 1
 4955
 0.19
chr9_91362060_91362437 0.17 Zic4
 zinc finger protein of the cerebellum 4
 165
 0.86
chr11_74638791_74638959 0.17 Cluh
 clustered mitochondria (cluA/CLU1) homolog
 10620
 0.15
chr13_31808871_31809301 0.16 Foxc1
 forkhead box C1
 2453
 0.26
chr7_79789753_79789904 0.16 Gm44705
 predicted gene 44705
 797
 0.44
chr4_9825489_9825685 0.16 Gdf6
 growth differentiation factor 6
 18785
 0.21
chr13_3634179_3634726 0.16 Asb13
 ankyrin repeat and SOCS box-containing 13
 353
 0.85
chr12_51811916_51812067 0.16 Hectd1
 HECT domain E3 ubiquitin protein ligase 1
 17327
 0.18
chr17_12665076_12665233 0.16 Slc22a1
 solute carrier family 22 (organic cation transporter), member 1
 10542
 0.17
chr6_95675108_95675466 0.16 Suclg2
 succinate-Coenzyme A ligase, GDP-forming, beta subunit
 17595
 0.29
chr2_157007239_157007486 0.16 Dsn1
 DSN1 homolog, MIS12 kinetochore complex component
 208
 0.9
chr4_40205002_40205156 0.16 Ddx58
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
 3464
 0.22
chrX_140599839_140600148 0.16 Tsc22d3
 TSC22 domain family, member 3
 666
 0.67
chr13_21364400_21364561 0.16 Zscan12
 zinc finger and SCAN domain containing 12
 1195
 0.26
chr9_96652901_96653065 0.16 Rasa2
 RAS p21 protein activator 2
 21366
 0.15
chr5_25705756_25706065 0.16 Xrcc2
 X-ray repair complementing defective repair in Chinese hamster cells 2
 85
 0.96
chr2_130667701_130668092 0.16 Itpa
 inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
 31
 0.95
chr9_77776976_77777127 0.16 Gclc
 glutamate-cysteine ligase, catalytic subunit
 10909
 0.14
chr11_50388012_50388306 0.16 Hnrnph1
 heterogeneous nuclear ribonucleoprotein H1
 3196
 0.18
chr4_135516112_135516333 0.16 Gm25317
 predicted gene, 25317
 3743
 0.16
chr16_38621171_38621322 0.15 Tmem39a
 transmembrane protein 39a
 33207
 0.12
chr5_32470156_32470325 0.15 Gm43313
 predicted gene 43313
 3045
 0.16
chr10_67051361_67051540 0.15 Reep3
 receptor accessory protein 3
 14128
 0.18
chr4_105206975_105207547 0.15 Plpp3
 phospholipid phosphatase 3
 49914
 0.17
chr12_79969197_79969348 0.15 Gm8275
 predicted gene 8275
 10579
 0.18
chr9_110170831_110171182 0.15 Smarcc1
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
 14726
 0.15
chr9_74991465_74991644 0.15 Fam214a
 family with sequence similarity 214, member A
 15443
 0.18
chr8_88362626_88362796 0.15 Brd7
 bromodomain containing 7
 517
 0.8
chr16_30386539_30386690 0.15 Atp13a3
 ATPase type 13A3
 1871
 0.37
chr5_123720048_123720199 0.15 Zcchc8
 zinc finger, CCHC domain containing 8
 608
 0.62
chr15_38298706_38299133 0.15 Klf10
 Kruppel-like factor 10
 80
 0.96
chr14_75154835_75154992 0.15 Gm15628
 predicted gene 15628
 18001
 0.14
chr9_77933320_77933504 0.15 Elovl5
 ELOVL family member 5, elongation of long chain fatty acids (yeast)
 7879
 0.15
chr15_77153517_77153722 0.15 Rbfox2
 RNA binding protein, fox-1 homolog (C. elegans) 2
 63
 0.97
chr1_74034473_74034624 0.15 Tns1
 tensin 1
 2585
 0.32
chrX_140457137_140457466 0.15 Prps1
 phosphoribosyl pyrophosphate synthetase 1
 688
 0.7
chr19_44554722_44555277 0.15 Ndufb8
 NADH:ubiquinone oxidoreductase subunit B8
 13
 0.96
chr17_33254646_33254995 0.15 Zfp955a
 zinc finger protein 955A
 325
 0.83
chr3_21634214_21634369 0.15 Gm17935
 predicted gene, 17935
 14096
 0.22
chr11_32532281_32532432 0.15 Efcab9
 EF-hand calcium binding domain 9
 275
 0.84
chr1_21255692_21256129 0.15 Gsta3
 glutathione S-transferase, alpha 3
 2389
 0.17
chr11_108254530_108254689 0.15 Gm11655
 predicted gene 11655
 72759
 0.09
chr12_64966293_64966672 0.15 Togaram1
 TOG array regulator of axonemal microtubules 1
 426
 0.67
chr13_101719143_101719316 0.15 Pik3r1
 phosphoinositide-3-kinase regulatory subunit 1
 17125
 0.2
chr5_142814483_142814698 0.15 Tnrc18
 trinucleotide repeat containing 18
 2790
 0.25
chr8_35257088_35257239 0.14 Gm34597
 predicted gene, 34597
 11684
 0.17
chr11_96887053_96887204 0.14 Gm11523
 predicted gene 11523
 13174
 0.08
chr3_122888651_122888824 0.14 Fabp2
 fatty acid binding protein 2, intestinal
 6335
 0.14
chr7_101301283_101301902 0.14 Atg16l2
 autophagy related 16-like 2 (S. cerevisiae)
 435
 0.73
chr17_84740428_84740579 0.14 Lrpprc
 leucine-rich PPR-motif containing
 9319
 0.17
chr14_18369590_18369741 0.14 Ube2e1
 ubiquitin-conjugating enzyme E2E 1
 37806
 0.15
chr19_45805094_45805257 0.14 Kcnip2
 Kv channel-interacting protein 2
 1601
 0.31
chr14_74947553_74947749 0.14 Lrch1
 leucine-rich repeats and calponin homology (CH) domain containing 1
 215
 0.94
chr9_87740016_87740167 0.14 Gm37374
 predicted gene, 37374
 71
 0.97
chr4_133241348_133241936 0.14 Map3k6
 mitogen-activated protein kinase kinase kinase 6
 824
 0.47
chr7_29211431_29211967 0.14 Catsperg1
 cation channel sperm associated auxiliary subunit gamma 1
 204
 0.86
chr18_84881160_84881318 0.14 Cyb5a
 cytochrome b5 type A (microsomal)
 3638
 0.2
chr13_12650352_12650636 0.14 Gpr137b-ps
 G protein-coupled receptor 137B, pseudogene
 106
 0.94
chr8_121829970_121830295 0.14 Gm24283
 predicted gene, 24283
 304
 0.64
chr9_86710183_86710334 0.14 Gm37484
 predicted gene, 37484
 1746
 0.22
chr4_98396272_98396452 0.14 Patj
 PATJ, crumbs cell polarity complex component
 470
 0.78
chr2_127070770_127071004 0.14 Blvra
 biliverdin reductase A
 194
 0.93
chr1_78510560_78510953 0.14 Mogat1
 monoacylglycerol O-acyltransferase 1
 235
 0.88
chr5_92525314_92525505 0.14 Scarb2
 scavenger receptor class B, member 2
 18576
 0.14
chr1_131620226_131620377 0.14 Gm8532
 predicted gene 8532
 12668
 0.14
chr4_34886892_34887287 0.14 Zfp292
 zinc finger protein 292
 4129
 0.16
chr12_71042601_71042779 0.14 Arid4a
 AT rich interactive domain 4A (RBP1-like)
 5651
 0.18
chr17_34114308_34114459 0.14 Brd2
 bromodomain containing 2
 327
 0.65
chr13_23560777_23560941 0.14 H3c6
 H3 clustered histone 6
 1510
 0.11
chr15_8169422_8169573 0.14 Cplane1
 ciliogenesis and planar polarity effector 1
 391
 0.86
chr7_4739556_4740137 0.14 Kmt5c
 lysine methyltransferase 5C
 269
 0.73
chr13_54323124_54323298 0.14 Gm48622
 predicted gene, 48622
 4669
 0.18
chr5_22587487_22587999 0.14 Gm9057
 predicted gene 9057
 23786
 0.11
chr1_21242608_21242925 0.14 Gsta3
 glutathione S-transferase, alpha 3
 2137
 0.2
chr11_82764474_82764643 0.14 Zfp830
 zinc finger protein 830
 213
 0.5
chr17_27555746_27555972 0.14 Hmga1
 high mobility group AT-hook 1
 638
 0.34
chr11_116477086_116477269 0.14 Prpsap1
 phosphoribosyl pyrophosphate synthetase-associated protein 1
 562
 0.6
chr11_87704950_87705126 0.14 1110028F11Rik
 RIKEN cDNA 1110028F11 gene
 2915
 0.14
chr2_90536611_90536782 0.13 Ptprj
 protein tyrosine phosphatase, receptor type, J
 43951
 0.13
chr5_129701203_129701458 0.13 Septin14
 septin 14
 2929
 0.16
chr7_49525838_49525989 0.13 Nav2
 neuron navigator 2
 22279
 0.22
chr4_141325202_141325608 0.13 Epha2
 Eph receptor A2
 8492
 0.1
chr1_39577801_39577984 0.13 Rnf149
 ring finger protein 149
 487
 0.69
chr8_123040127_123040722 0.13 Ankrd11
 ankyrin repeat domain 11
 1596
 0.22
chr4_149980056_149980645 0.13 H6pd
 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
 20915
 0.13
chr15_58942719_58942985 0.13 Ndufb9
 NADH:ubiquinone oxidoreductase subunit B9
 9044
 0.13
chr2_70798248_70798536 0.13 Tlk1
 tousled-like kinase 1
 26836
 0.18
chr12_100629644_100629796 0.13 Gm48585
 predicted gene, 48585
 2927
 0.22
chrX_48623364_48623778 0.13 Slc25a14
 solute carrier family 25 (mitochondrial carrier, brain), member 14
 7
 0.97
chr14_8003568_8003795 0.13 Abhd6
 abhydrolase domain containing 6
 715
 0.66
chr2_11464949_11465110 0.13 Pfkfb3
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
 17082
 0.12
chr11_88194414_88194594 0.13 Cuedc1
 CUE domain containing 1
 6683
 0.18
chr6_108456531_108456780 0.13 Itpr1
 inositol 1,4,5-trisphosphate receptor 1
 2048
 0.31
chr3_107808036_107808187 0.13 Gm36211
 predicted gene, 36211
 25428
 0.1
chr8_54925357_54925725 0.13 Gpm6a
 glycoprotein m6a
 29302
 0.13
chr1_171215629_171216025 0.13 Nr1i3
 nuclear receptor subfamily 1, group I, member 3
 1478
 0.19
chr15_82704114_82704796 0.13 Cyp2d38-ps
 cytochrome P450, family 2, subfamily d, member 38, pseudogene
 2810
 0.12
chr2_91636079_91636258 0.13 F2
 coagulation factor II
 227
 0.88
chr2_75608717_75608911 0.13 Gm13655
 predicted gene 13655
 24568
 0.15
chr10_99264296_99264649 0.13 Dusp6
 dual specificity phosphatase 6
 195
 0.9
chr4_58912910_58913089 0.13 Ecpas
 Ecm29 proteasome adaptor and scaffold
 250
 0.91
chr2_39140389_39140542 0.13 Gm18791
 predicted gene, 18791
 13499
 0.12
chr5_9101079_9101755 0.13 Tmem243
 transmembrane protein 243, mitochondrial
 670
 0.68
chr1_67039034_67039385 0.13 Lancl1
 LanC (bacterial lantibiotic synthetase component C)-like 1
 337
 0.9
chr3_32511301_32511465 0.13 Zfp639
 zinc finger protein 639
 487
 0.61
chr12_17401853_17402148 0.13 Gm36752
 predicted gene, 36752
 34618
 0.12
chr15_54612739_54612908 0.13 Mal2
 mal, T cell differentiation protein 2
 41631
 0.18
chr9_15307654_15307814 0.13 Taf1d
 TATA-box binding protein associated factor, RNA polymerase I, D
 8
 0.89
chr3_122729656_122729846 0.13 Pde5a
 phosphodiesterase 5A, cGMP-specific
 181
 0.95
chr14_17725657_17725828 0.13 Gm48320
 predicted gene, 48320
 45380
 0.18
chr15_75893944_75894142 0.13 Naprt
 nicotinate phosphoribosyltransferase
 247
 0.81
chr3_89410971_89411311 0.13 Flad1
 flavin adenine dinucleotide synthetase 1
 640
 0.44
chr11_100505644_100505795 0.13 Acly
 ATP citrate lyase
 6621
 0.1
chr13_24281700_24281890 0.13 Carmil1
 capping protein regulator and myosin 1 linker 1
 1000
 0.43
chr19_37442280_37442502 0.13 Hhex
 hematopoietically expressed homeobox
 5652
 0.13
chr7_114431752_114431903 0.13 Pde3b
 phosphodiesterase 3B, cGMP-inhibited
 16546
 0.2
chr5_142421234_142421418 0.13 Foxk1
 forkhead box K1
 19826
 0.19
chr3_98290887_98291082 0.13 Gm43189
 predicted gene 43189
 3996
 0.17
chr4_103394349_103394515 0.13 Gm12718
 predicted gene 12718
 11911
 0.2
chr13_117024345_117024496 0.13 Parp8
 poly (ADP-ribose) polymerase family, member 8
 853
 0.64
chr10_20071278_20071572 0.13 Map3k5
 mitogen-activated protein kinase kinase kinase 5
 28100
 0.19
chr17_83514778_83514946 0.13 Cox7a2l
 cytochrome c oxidase subunit 7A2 like
 532
 0.84
chr7_28951879_28952178 0.13 Actn4
 actinin alpha 4
 2269
 0.17
chr5_24597266_24597434 0.12 Smarcd3
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
 361
 0.74
chr15_59062348_59062499 0.12 Mtss1
 MTSS I-BAR domain containing 1
 6959
 0.24
chr7_28104816_28105003 0.12 Fcgbp
 Fc fragment of IgG binding protein
 4100
 0.13
chr5_63788784_63789107 0.12 Nwd2
 NACHT and WD repeat domain containing 2
 11517
 0.21
chr6_144503491_144503691 0.12 Sox5os2
 SRY (sex determining region Y)-box 5, opposite strand 2
 22366
 0.26
chr8_23207373_23207572 0.12 Gpat4
 glycerol-3-phosphate acyltransferase 4
 873
 0.36

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of E2f7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1 0.3 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.2 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.2 GO:0071926 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.1 0.2 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.1 0.1 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.1 0.2 GO:0046149 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.2 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.1 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 0.3 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.1 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.1 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:0006714 sesquiterpenoid metabolic process(GO:0006714)
0.0 0.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.1 GO:0003289 atrial septum primum morphogenesis(GO:0003289)
0.0 0.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.2 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.1 GO:0042148 strand invasion(GO:0042148)
0.0 0.1 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.0 0.1 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.2 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.3 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.0 0.1 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.1 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.0 GO:1903977 positive regulation of glial cell migration(GO:1903977)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0032513 negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.0 0.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.1 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.1 GO:2000834 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.1 GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.1 GO:0043173 nucleotide salvage(GO:0043173)
0.0 0.1 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.1 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.0 0.0 GO:2000437 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.1 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.1 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.0 0.0 GO:0061010 gall bladder development(GO:0061010)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.1 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.1 GO:0009092 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0 0.1 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.0 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.0 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:2000698 positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698)
0.0 0.0 GO:1903333 negative regulation of protein folding(GO:1903333)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 0.0 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0 0.1 GO:1903961 positive regulation of anion transmembrane transport(GO:1903961)
0.0 0.1 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 0.1 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.0 0.1 GO:0071462 cellular response to water stimulus(GO:0071462)
0.0 0.2 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.0 GO:0007403 glial cell fate determination(GO:0007403)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.0 GO:0009173 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0099515 actin filament-based transport(GO:0099515)
0.0 0.1 GO:0031627 telomeric loop formation(GO:0031627)
0.0 0.1 GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0061144 alveolar secondary septum development(GO:0061144)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.0 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.0 GO:1990314 cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0 0.0 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.0 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.0 GO:0034137 positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.0 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0044597 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.0 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.0 GO:0060931 sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.0 0.0 GO:0010912 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.2 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.0 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.0 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.0 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.0 GO:0071035 polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.0 0.2 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.1 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.1 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0 0.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.0 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.0 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.0 0.0 GO:0090155 negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156)
0.0 0.0 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 0.1 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.1 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.1 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0 0.0 GO:0032056 positive regulation of translation in response to stress(GO:0032056) positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.0 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.0 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.0 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.0 0.1 GO:0060546 negative regulation of necroptotic process(GO:0060546)
0.0 0.0 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.0 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.0 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.0 GO:0003099 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.2 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.0 GO:0060486 Clara cell differentiation(GO:0060486)
0.0 0.0 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.0 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.0 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.0 GO:0009629 response to gravity(GO:0009629)
0.0 0.1 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.0 GO:0072602 interleukin-4 secretion(GO:0072602)
0.0 0.0 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.0 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.0 0.0 GO:0061643 chemorepulsion of axon(GO:0061643)
0.0 0.1 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.1 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.0 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.0 GO:0006069 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.1 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.0 GO:0009169 ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.0 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.2 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.0 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.0 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.0 GO:0036258 multivesicular body assembly(GO:0036258)
0.0 0.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.3 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.4 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.0 GO:0097413 Lewy body(GO:0097413)
0.0 0.0 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.0 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.0 GO:0031523 Myb complex(GO:0031523)
0.0 0.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.0 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.0 GO:0033269 internode region of axon(GO:0033269)
0.0 0.0 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.0 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.0 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.0 GO:0046691 intracellular canaliculus(GO:0046691)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0001939 female pronucleus(GO:0001939)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1 0.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.1 GO:0035276 ethanol binding(GO:0035276)
0.0 0.2 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.2 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.2 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0032564 dATP binding(GO:0032564)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.0 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.0 0.0 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.5 GO:0051723 protein methylesterase activity(GO:0051723)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.0 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.0 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.1 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.0 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.0 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.0 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.0 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.0 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.0 GO:0032190 acrosin binding(GO:0032190)
0.0 0.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.0 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.0 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination