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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Ebf3

Z-value: 1.91

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Transcription factors associated with Ebf3

Gene Symbol	Gene ID	Gene Info
Ebf3 Ensembl NCBI MGI UniProt	ENSMUSG00000010476.7	Ebf3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Ebf3	chr7_137319831_137319983	5462	0.203989	-0.97	1.0e-03	Click!
Ebf3	chr7_137312803_137312954	1038	0.541003	-0.78	6.9e-02	Click!
Ebf3	chr7_137221777_137222201	4813	0.198531	0.73	9.7e-02	Click!
Ebf3	chr7_137288505_137288677	21053	0.175898	-0.73	1.0e-01	Click!
Ebf3	chr7_137223230_137223397	3489	0.222007	0.56	2.5e-01	Click!

Activity of the Ebf3 motif across conditions

Conditions sorted by the z-value of the Ebf3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_108330984_108331146	1.63	Apoh	apolipoprotein H	12289	0.18
chr5_113152964_113153205	1.56	Gm42161	predicted gene, 42161	7756	0.11
chr8_119416007_119416158	1.54	Osgin1	oxidative stress induced growth inhibitor 1	18042	0.13
chr18_81199291_81199673	1.29	4930594M17Rik	RIKEN cDNA 4930594M17 gene	36584	0.17
chr8_119415579_119415730	1.12	Osgin1	oxidative stress induced growth inhibitor 1	18470	0.13
chr4_141347370_141347546	1.11	Gm13074	predicted gene 13074	356	0.71
chr11_98767399_98767584	1.07	Nr1d1	nuclear receptor subfamily 1, group D, member 1	2935	0.14
chr10_80071687_80071929	1.06	Sbno2	strawberry notch 2	3592	0.11
chr8_119418852_119419003	1.06	Osgin1	oxidative stress induced growth inhibitor 1	15197	0.14
chr10_80589579_80589735	1.04	Gm29093	predicted gene 29093	133	0.83
chr6_142459054_142459205	1.02	Gys2	glycogen synthase 2	13980	0.16
chr17_84048784_84048940	1.01	Gm49967	predicted gene, 49967	11972	0.13
chr19_40661223_40661381	0.99	Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	809	0.55
chr11_75459071_75459222	0.99	Mir22hg	Mir22 host gene (non-protein coding)	2393	0.12
chr2_72117636_72117826	0.98	Rapgef4	Rap guanine nucleotide exchange factor (GEF) 4	22980	0.18
chr19_42659380_42659560	0.97	Gm25216	predicted gene, 25216	40432	0.13
chr1_72255173_72255368	0.89	Gm25939	predicted gene, 25939	262	0.86
chr4_107617669_107617841	0.87	Glis1	GLIS family zinc finger 1	2755	0.26
chr1_156996616_156996772	0.87	Gm10531	predicted gene 10531	46853	0.11
chr5_63839973_63840346	0.87	0610040J01Rik	RIKEN cDNA 0610040J01 gene	27639	0.17
chr4_149798966_149799139	0.86	Gm13065	predicted gene 13065	5633	0.1
chr2_132221652_132221803	0.86	Tmem230	transmembrane protein 230	25927	0.13
chr2_91476449_91476629	0.82	Lrp4	low density lipoprotein receptor-related protein 4	220	0.92
chr8_119442578_119443025	0.81	Necab2	N-terminal EF-hand calcium binding protein 2	3918	0.18
chr11_101658377_101658659	0.81	Rnu2-10	U2 small nuclear RNA 10	280	0.81
chr5_110797818_110798001	0.80	Ulk1	unc-51 like kinase 1	2075	0.19
chr4_155245715_155246079	0.80	Faap20	Fanconi anemia core complex associated protein 20	3905	0.19
chr10_93736289_93736487	0.80	Gm15963	predicted gene 15963	8181	0.16
chr9_43467006_43467175	0.79	Gm28215	predicted gene 28215	2332	0.29
chr15_72833192_72833390	0.79	Peg13	paternally expressed 13	22967	0.22
chr3_85991904_85992061	0.79	Prss48	protease, serine 48	10509	0.12
chr11_59885731_59885882	0.78	Gm12714	predicted gene 12714	12568	0.11
chr19_57118911_57119062	0.78	Ablim1	actin-binding LIM protein 1	21	0.99
chr3_95905207_95905371	0.78	Car14	carbonic anhydrase 14	598	0.51
chr5_96222210_96222544	0.78	Mrpl1	mitochondrial ribosomal protein L1	12233	0.22
chr14_65376633_65376799	0.77	Zfp395	zinc finger protein 395	1323	0.42
chr12_25416673_25416856	0.76	Gm36723	predicted gene, 36723	22009	0.24
chr7_99168829_99169197	0.74	Dgat2	diacylglycerol O-acyltransferase 2	1093	0.4
chr9_40456362_40456513	0.74	Gramd1b	GRAM domain containing 1B	673	0.66
chr5_116445735_116445902	0.73	Srrm4	serine/arginine repetitive matrix 4	1026	0.42
chr2_50143549_50143721	0.73	Lypd6	LY6/PLAUR domain containing 6	15266	0.28
chr5_112486568_112486719	0.73	Sez6l	seizure related 6 homolog like	11516	0.16
chr6_108233581_108233762	0.72	Itpr1	inositol 1,4,5-trisphosphate receptor 1	19287	0.22
chr14_117648617_117648937	0.72	Mir6239	microRNA 6239	305070	0.01
chr7_112202260_112202451	0.72	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	23501	0.22
chr15_102004327_102004492	0.71	Krt8	keratin 8	73	0.67
chr1_168682011_168682173	0.71	1700063I16Rik	RIKEN cDNA 1700063I16 gene	6210	0.33
chr14_20892049_20892245	0.71	Gm6128	predicted pseudogene 6128	35726	0.13
chr5_113133182_113133354	0.70	2900026A02Rik	RIKEN cDNA 2900026A02 gene	4718	0.12
chr13_56648096_56648259	0.70	Tgfbi	transforming growth factor, beta induced	16964	0.19
chr2_174818226_174818391	0.70	Gm14617	predicted gene 14617	20326	0.16
chr19_55229779_55229947	0.69	Gucy2g	guanylate cyclase 2g	11373	0.16
chr15_82671135_82671600	0.69	Cyp2d36-ps	cytochrome P450, family 2, subfamily d, polypeptide 36, pseudogene	11890	0.08
chr19_23150997_23151148	0.68	Mir1192	microRNA 1192	1641	0.33
chr11_101952845_101953096	0.68	4930417O22Rik	RIKEN cDNA 4930417O22 gene	549	0.6
chr10_128247108_128247286	0.68	Timeless	timeless circadian clock 1	88	0.92
chr14_40914867_40915027	0.68	Tspan14	tetraspanin 14	19369	0.18
chr9_105809628_105809794	0.67	Col6a6	collagen, type VI, alpha 6	63	0.98
chr5_36814696_36814866	0.66	Man2b2	mannosidase 2, alpha B2	1818	0.27
chr2_30242678_30242858	0.66	Gm28035	predicted gene, 28035	2201	0.15
chr5_125226466_125226633	0.66	Gm32585	predicted gene, 32585	46266	0.11
chr15_66845461_66845621	0.66	Sla	src-like adaptor	13712	0.19
chr1_72244368_72244519	0.66	Gm24497	predicted gene, 24497	230	0.88
chr2_59629848_59630022	0.65	Tanc1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1	128	0.98
chr1_172312776_172313173	0.65	Igsf8	immunoglobulin superfamily, member 8	607	0.57
chr7_63765119_63765297	0.65	Gm44718	predicted gene 44718	666	0.69
chr1_72226394_72226550	0.65	Gm25360	predicted gene, 25360	232	0.89
chr5_121850762_121850913	0.64	Pheta1	PH domain containing endocytic trafficking adaptor 1	1832	0.19
chr9_43261927_43262320	0.64	D630033O11Rik	RIKEN cDNA D630033O11 gene	2010	0.28
chr4_116985890_116986058	0.63	Urod	uroporphyrinogen decarboxylase	5691	0.1
chr6_136828326_136828482	0.62	Wbp11	WW domain binding protein 11	171	0.72
chr12_111160070_111160239	0.62	Traf3	TNF receptor-associated factor 3	6216	0.18
chr3_122120313_122120499	0.61	Abca4	ATP-binding cassette, sub-family A (ABC1), member 4	366	0.85
chr7_27490840_27491009	0.61	Sertad1	SERTA domain containing 1	3549	0.11
chr2_31761701_31761878	0.61	Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	1616	0.33
chr13_92609818_92609992	0.61	Serinc5	serine incorporator 5	1186	0.52
chr1_191957043_191957198	0.60	Rd3	retinal degeneration 3	20250	0.11
chr12_111514450_111514666	0.60	Gm40578	predicted gene, 40578	13718	0.1
chr12_82086163_82086328	0.59	n-R5s62	nuclear encoded rRNA 5S 62	64223	0.1
chr14_41101376_41101542	0.59	Mat1a	methionine adenosyltransferase I, alpha	3576	0.15
chr2_124370043_124370219	0.59	4930583P06Rik	RIKEN cDNA 4930583P06 gene	147800	0.05
chr16_22901028_22901197	0.58	Ahsg	alpha-2-HS-glycoprotein	6248	0.12
chr19_58439431_58439649	0.57	Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	14926	0.22
chr5_74648783_74649196	0.57	Lnx1	ligand of numb-protein X 1	25468	0.16
chr10_76579912_76580104	0.57	Ftcd	formiminotransferase cyclodeaminase	4356	0.13
chr14_54431415_54431610	0.57	Mmp14	matrix metallopeptidase 14 (membrane-inserted)	100	0.92
chr11_101645414_101645758	0.57	Gm23971	predicted gene, 23971	344	0.73
chr11_87662505_87662671	0.56	Rnf43	ring finger protein 43	134	0.94
chr3_152402367_152402529	0.56	Zzz3	zinc finger, ZZ domain containing 3	5754	0.12
chr11_68970449_68970600	0.55	Slc25a35	solute carrier family 25, member 35	2376	0.12
chr14_32008010_32008220	0.55	4930425P05Rik	RIKEN cDNA 4930425P05 gene	4887	0.17
chr16_10366678_10366849	0.55	Gm1600	predicted gene 1600	19172	0.14
chr11_101627513_101628017	0.55	Rdm1	RAD52 motif 1	177	0.69
chr11_5846893_5847128	0.55	Polm	polymerase (DNA directed), mu	8994	0.11
chr9_120738073_120738234	0.55	Gm47064	predicted gene, 47064	12990	0.13
chr9_32674052_32674248	0.55	Ets1	E26 avian leukemia oncogene 1, 5' domain	21872	0.15
chr8_72147470_72147621	0.54	Gm26586	predicted gene, 26586	6725	0.08
chr12_104986096_104986278	0.54	Syne3	spectrin repeat containing, nuclear envelope family member 3	12490	0.12
chr6_100144030_100144341	0.54	2010109P13Rik	RIKEN cDNA 2010109P13 gene	371	0.9
chr5_138756463_138756623	0.54	Fam20c	family with sequence similarity 20, member C	1456	0.41
chr11_101641924_101642238	0.54	Gm24950	predicted gene, 24950	333	0.74
chr7_87938394_87938545	0.54	Gm44927	predicted gene 44927	47720	0.17
chr1_86442760_86442964	0.54	Tex44	testis expressed 44	16533	0.11
chr11_63827398_63827577	0.54	Gm12288	predicted gene 12288	9187	0.23
chr9_46379532_46379689	0.53	Gm47141	predicted gene, 47141	17752	0.13
chr2_119355713_119355881	0.53	Chac1	ChaC, cation transport regulator 1	4568	0.16
chr5_113122736_113122907	0.53	F830115B05Rik	RIKEN cDNA F830115B05 gene	3357	0.14
chr5_35737574_35737851	0.53	Sh3tc1	SH3 domain and tetratricopeptide repeats 1	2275	0.27
chr6_145679594_145679775	0.53	Tuba3b	tubulin, alpha 3B	63927	0.09
chr1_74386650_74386830	0.52	Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	3140	0.13
chr13_98594899_98595134	0.52	Gm4815	predicted gene 4815	18485	0.12
chr5_33123767_33123929	0.52	Gm15936	predicted gene 15936	2954	0.2
chr7_19866622_19866883	0.52	Gm44659	predicted gene 44659	4686	0.08
chr1_72851647_72851798	0.52	Igfbp2	insulin-like growth factor binding protein 2	3023	0.28
chr12_108370797_108370948	0.51	Eml1	echinoderm microtubule associated protein like 1	85	0.97
chr6_34727419_34727585	0.51	Npn2	neoplastic progression 2	596	0.66
chr5_137493763_137493914	0.51	Epo	erythropoietin	8022	0.07
chr5_123382074_123382225	0.51	Mlxip	MLX interacting protein	12649	0.07
chr9_123529517_123529735	0.51	Sacm1l	SAC1 suppressor of actin mutations 1-like (yeast)	133	0.96
chr14_20654842_20654993	0.51	Myoz1	myozenin 1	1545	0.21
chr15_73668210_73668361	0.50	1700010B13Rik	RIKEN cDNA 1700010B13 gene	22411	0.14
chr9_32657200_32657375	0.50	Ets1	E26 avian leukemia oncogene 1, 5' domain	21039	0.15
chr7_27607606_27607784	0.50	Akt2	thymoma viral proto-oncogene 2	53	0.95
chr16_32124485_32124636	0.49	Gm15729	predicted gene 15729	15695	0.1
chr2_3657810_3658181	0.49	Gm13183	predicted gene 13183	22595	0.15
chr2_159826405_159826556	0.49	Gm11446	predicted gene 11446	32810	0.19
chr2_27504250_27504425	0.48	Brd3	bromodomain containing 3	3325	0.18
chr15_73492343_73492494	0.48	Gm19811	predicted gene, 19811	4879	0.19
chr7_84145705_84145865	0.48	Abhd17c	abhydrolase domain containing 17C	2030	0.26
chr3_97158666_97158826	0.48	Acp6	acid phosphatase 6, lysophosphatidic	31	0.97
chr2_166153441_166153627	0.48	Sulf2	sulfatase 2	889	0.57
chr9_106452941_106453115	0.48	Gm28959	predicted gene 28959	110	0.68
chr15_101260556_101260749	0.48	Nr4a1	nuclear receptor subfamily 4, group A, member 1	6194	0.11
chr9_44129712_44129877	0.47	Mcam	melanoma cell adhesion molecule	4675	0.07
chr1_84422591_84422769	0.47	Gm37959	predicted gene, 37959	27281	0.21
chr4_128950655_128950816	0.47	Azin2	antizyme inhibitor 2	10663	0.15
chr9_63043233_63043407	0.47	Gm24526	predicted gene, 24526	15760	0.17
chr11_119856806_119856957	0.47	Rptor	regulatory associated protein of MTOR, complex 1	563	0.72
chr8_126839083_126839255	0.47	A630001O12Rik	RIKEN cDNA A630001O12 gene	64	0.98
chr15_62712887_62713046	0.47	Gm24810	predicted gene, 24810	59962	0.14
chr11_4031603_4031903	0.47	Sec14l4	SEC14-like lipid binding 4	30	0.96
chr1_40117818_40118037	0.47	Gm37347	predicted gene, 37347	29416	0.14
chr2_152817536_152817750	0.47	Bcl2l1	BCL2-like 1	10892	0.12
chr7_45019247_45019425	0.46	Rras	related RAS viral (r-ras) oncogene	134	0.86
chr9_122695637_122695788	0.46	Gm35501	predicted gene, 35501	6083	0.11
chr5_137375760_137375924	0.46	Ephb4	Eph receptor B4	25329	0.08
chr10_21383047_21383223	0.46	Aldh8a1	aldehyde dehydrogenase 8 family, member A1	5788	0.14
chr19_28677852_28678003	0.46	D930032P07Rik	RIKEN cDNA D930032P07 gene	297	0.78
chr12_79292996_79293163	0.46	Zfyve26	zinc finger, FYVE domain containing 26	3193	0.23
chr7_129524479_129524630	0.46	Wdr11	WD repeat domain 11	67309	0.12
chrX_74328709_74328905	0.46	Plxna3	plexin A3	259	0.78
chr8_117198134_117198453	0.46	Gan	giant axonal neuropathy	40156	0.14
chr11_82428957_82429108	0.46	Tmem132e	transmembrane protein 132E	9225	0.23
chr16_31048299_31048452	0.46	Xxylt1	xyloside xylosyltransferase 1	13052	0.19
chr11_89028954_89029121	0.46	Trim25	tripartite motif-containing 25	29661	0.09
chr14_61037704_61037855	0.46	Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	112	0.6
chr16_23061809_23062006	0.46	Kng1	kininogen 1	3514	0.09
chr8_119443770_119443946	0.45	Necab2	N-terminal EF-hand calcium binding protein 2	2861	0.21
chr11_117872061_117872251	0.45	Tha1	threonine aldolase 1	245	0.79
chr9_90198554_90198732	0.45	Adamts7	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7	3515	0.2
chr6_145182126_145182277	0.45	Gm15543	predicted gene 15543	74	0.95
chr6_108519456_108519677	0.45	Itpr1	inositol 1,4,5-trisphosphate receptor 1	834	0.55
chr3_146617776_146618365	0.45	Dnase2b	deoxyribonuclease II beta	2474	0.2
chr4_138366734_138366984	0.45	Cda	cytidine deaminase	1133	0.36
chr15_97253131_97253396	0.45	Pced1b	PC-esterase domain containing 1B	4190	0.23
chr15_53325064_53325247	0.45	Ext1	exostosin glycosyltransferase 1	20504	0.25
chr2_166153665_166153816	0.45	Sulf2	sulfatase 2	683	0.68
chr6_94640401_94640563	0.45	Lrig1	leucine-rich repeats and immunoglobulin-like domains 1	15043	0.2
chr12_103658352_103658505	0.45	Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	1216	0.31
chr13_37940722_37940896	0.45	Rreb1	ras responsive element binding protein 1	6207	0.22
chr4_105199436_105199630	0.45	Plpp3	phospholipid phosphatase 3	42186	0.19
chr5_108674989_108675212	0.44	Slc26a1	solute carrier family 26 (sulfate transporter), member 1	315	0.81
chr13_30660255_30660420	0.44	Dusp22	dual specificity phosphatase 22	236	0.94
chr3_146616407_146616685	0.44	Dnase2b	deoxyribonuclease II beta	950	0.46
chr4_128804978_128805273	0.44	Zfp362	zinc finger protein 362	920	0.55
chr13_52021964_52022187	0.44	Gm37872	predicted gene, 37872	148	0.97
chr12_36182746_36182897	0.44	Gm19046	predicted gene, 19046	10453	0.13
chr1_46908404_46908555	0.43	Gm28527	predicted gene 28527	11600	0.18
chr10_80917355_80917522	0.43	Lmnb2	lamin B2	413	0.7
chr15_79734404_79734589	0.43	Sun2	Sad1 and UNC84 domain containing 2	1455	0.22
chr2_169115164_169115359	0.43	Gm14258	predicted gene 14258	8808	0.23
chr13_110568602_110568764	0.43	Gm33045	predicted gene, 33045	58605	0.14
chr6_128494689_128494877	0.42	Pzp	PZP, alpha-2-macroglobulin like	440	0.68
chr4_125125048_125125199	0.42	Zc3h12a	zinc finger CCCH type containing 12A	2603	0.22
chr15_96751773_96751965	0.42	Gm8888	predicted gene 8888	15209	0.2
chr17_46031864_46032231	0.42	Vegfa	vascular endothelial growth factor A	232	0.92
chr6_40634916_40635087	0.42	Mgam	maltase-glucoamylase	6170	0.17
chr7_142330360_142330565	0.42	Ifitm10	interferon induced transmembrane protein 10	7560	0.09
chr7_139366642_139366843	0.42	Inpp5a	inositol polyphosphate-5-phosphatase A	22367	0.2
chr12_55473766_55473977	0.42	Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	17939	0.16
chr2_32927869_32928134	0.42	Fam129b	family with sequence similarity 129, member B	6359	0.12
chr2_45114016_45114230	0.42	Zeb2	zinc finger E-box binding homeobox 2	615	0.66
chr10_86273864_86274186	0.42	Timp3	tissue inhibitor of metalloproteinase 3	26347	0.19
chr1_184072575_184072786	0.42	Dusp10	dual specificity phosphatase 10	38299	0.17
chr11_98981808_98981976	0.42	Gjd3	gap junction protein, delta 3	1124	0.33
chr9_62522367_62522518	0.42	Coro2b	coronin, actin binding protein, 2B	2006	0.36
chr17_45563761_45563930	0.41	Slc35b2	solute carrier family 35, member B2	29	0.95
chr8_119443050_119443280	0.41	Necab2	N-terminal EF-hand calcium binding protein 2	3554	0.18
chr3_96953916_96954079	0.41	Gja8	gap junction protein, alpha 8	27977	0.12
chr16_44060984_44061135	0.41	Gramd1c	GRAM domain containing 1C	486	0.81

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Ebf3

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.2	0.5	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	0.6	GO:1904395	regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1	0.5	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1	0.5	GO:0002159	desmosome assembly(GO:0002159)
0.1	0.4	GO:0045472	response to ether(GO:0045472)
0.1	0.4	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.1	0.3	GO:0090259	regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1	0.5	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.1	0.4	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1	0.3	GO:1904220	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1	0.3	GO:0032439	endosome localization(GO:0032439)
0.1	0.4	GO:0021636	trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637)
0.1	0.3	GO:0035928	rRNA import into mitochondrion(GO:0035928)
0.1	0.4	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1	0.3	GO:0006566	threonine metabolic process(GO:0006566)
0.1	0.2	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1	0.4	GO:0042045	epithelial fluid transport(GO:0042045)
0.1	0.3	GO:0060268	negative regulation of respiratory burst(GO:0060268)
0.1	0.1	GO:0021828	cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.1	0.3	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.1	0.4	GO:0019532	oxalate transport(GO:0019532)
0.1	0.3	GO:0070814	hydrogen sulfide biosynthetic process(GO:0070814)
0.1	0.1	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.1	0.4	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.1	0.3	GO:1900378	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1	0.2	GO:0071895	odontoblast differentiation(GO:0071895)
0.1	0.4	GO:0019348	dolichol metabolic process(GO:0019348)
0.1	0.2	GO:0006106	fumarate metabolic process(GO:0006106)
0.1	0.3	GO:0032202	telomere assembly(GO:0032202)
0.1	0.3	GO:0042758	long-chain fatty acid catabolic process(GO:0042758)
0.1	0.3	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.1	0.3	GO:0070126	mitochondrial translational termination(GO:0070126)
0.1	0.3	GO:0000820	regulation of glutamine family amino acid metabolic process(GO:0000820)
0.1	0.3	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.1	0.4	GO:0015670	carbon dioxide transport(GO:0015670)
0.1	0.2	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.2	GO:0003383	apical constriction(GO:0003383)
0.1	0.2	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1	0.2	GO:0015819	lysine transport(GO:0015819)
0.1	0.4	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.1	0.5	GO:0035988	chondrocyte proliferation(GO:0035988)
0.1	0.2	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.1	0.2	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
0.1	0.2	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1	0.2	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1	0.2	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	0.2	GO:0030035	microspike assembly(GO:0030035)
0.1	0.1	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.1	0.2	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.1	0.3	GO:0014063	negative regulation of serotonin secretion(GO:0014063)
0.1	0.2	GO:0046878	positive regulation of saliva secretion(GO:0046878)
0.0	0.1	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.2	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
0.0	0.1	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0	0.2	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.5	GO:0006152	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0	0.1	GO:0071462	cellular response to water stimulus(GO:0071462)
0.0	0.4	GO:0097062	dendritic spine maintenance(GO:0097062)
0.0	0.1	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0	0.1	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.1	GO:2000587	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	0.1	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0	0.4	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.3	GO:0090205	positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.0	GO:0060167	regulation of adenosine receptor signaling pathway(GO:0060167)
0.0	0.1	GO:0033668	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:1902990	mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0	0.0	GO:0007403	glial cell fate determination(GO:0007403)
0.0	0.1	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0	0.2	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.0	0.1	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.2	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.0	0.2	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.1	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.0	0.2	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.0	GO:0035622	intrahepatic bile duct development(GO:0035622)
0.0	0.1	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.0	0.1	GO:0060336	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.1	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.1	GO:0009446	putrescine biosynthetic process(GO:0009446)
0.0	0.1	GO:0070889	platelet alpha granule organization(GO:0070889)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.1	GO:0036023	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0	0.1	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.2	GO:0002227	innate immune response in mucosa(GO:0002227)
0.0	0.2	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0	0.1	GO:0015772	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.2	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.1	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.0	0.2	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.3	GO:1900452	regulation of long term synaptic depression(GO:1900452)
0.0	0.1	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.2	GO:0032754	positive regulation of interleukin-5 production(GO:0032754)
0.0	0.1	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0	0.1	GO:0006172	ADP biosynthetic process(GO:0006172)
0.0	0.1	GO:0002155	regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0	0.0	GO:1904179	positive regulation of adipose tissue development(GO:1904179)
0.0	0.2	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.0	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.1	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.0	0.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.2	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.1	GO:0072679	thymocyte migration(GO:0072679) regulation of thymocyte migration(GO:2000410) positive regulation of thymocyte migration(GO:2000412)
0.0	0.1	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.0	0.0	GO:0038027	apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.0	0.1	GO:0061047	positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.1	GO:0031947	negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947)
0.0	0.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.2	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.1	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.0	0.3	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.0	0.3	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.1	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.4	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.1	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0	0.2	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.0	0.1	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0	0.2	GO:0044539	long-chain fatty acid import(GO:0044539)
0.0	0.1	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.5	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.1	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	0.4	GO:0052646	alditol phosphate metabolic process(GO:0052646)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.5	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.1	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.0	0.1	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.0	GO:0048320	axial mesoderm formation(GO:0048320)
0.0	0.1	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0	0.1	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531) nucleotide transmembrane transport(GO:1901679)
0.0	0.0	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.0	0.1	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	0.0	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.3	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.2	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.0	0.0	GO:1903416	response to glycoside(GO:1903416)
0.0	0.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.1	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0	0.1	GO:1903964	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.3	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0	0.1	GO:1901631	positive regulation of presynaptic membrane organization(GO:1901631)
0.0	0.1	GO:0006621	protein retention in ER lumen(GO:0006621)
0.0	0.0	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.0	0.1	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0	0.1	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373)
0.0	0.1	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.0	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.1	GO:0032776	DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776)
0.0	0.1	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.1	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.0	GO:0045415	negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.0	0.0	GO:0072602	interleukin-4 secretion(GO:0072602)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.0	GO:0060486	Clara cell differentiation(GO:0060486)
0.0	0.1	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.2	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	0.1	GO:0015838	amino-acid betaine transport(GO:0015838)
0.0	0.0	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.0	0.0	GO:0070375	ERK5 cascade(GO:0070375)
0.0	0.1	GO:0046645	positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0	0.1	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.0	0.0	GO:0021778	oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.1	GO:2001168	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0	0.0	GO:0046643	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0	0.0	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.2	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.4	GO:0046039	GTP metabolic process(GO:0046039)
0.0	0.0	GO:0046098	guanine metabolic process(GO:0046098)
0.0	0.1	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0046078	dUMP metabolic process(GO:0046078)
0.0	0.1	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0	0.0	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.1	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.0	0.1	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.0	0.1	GO:0071910	determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.0	0.2	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.4	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.1	GO:0014028	notochord formation(GO:0014028)
0.0	0.1	GO:0043173	nucleotide salvage(GO:0043173)
0.0	0.1	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.0	GO:1904180	negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0	0.0	GO:1902837	amino acid import into cell(GO:1902837)
0.0	0.0	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.0	0.2	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.2	GO:0034389	lipid particle organization(GO:0034389)
0.0	0.2	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.0	GO:0032829	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.0	0.2	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.0	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
0.0	0.1	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.0	0.2	GO:0019184	nonribosomal peptide biosynthetic process(GO:0019184)
0.0	0.1	GO:0010388	cullin deneddylation(GO:0010388)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.0	0.1	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.1	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
0.0	0.0	GO:0070836	caveola assembly(GO:0070836)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.0	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.3	GO:0061001	regulation of dendritic spine morphogenesis(GO:0061001)
0.0	0.0	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.0	0.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.0	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061419)
0.0	0.0	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0	0.0	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0	0.0	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.0	GO:1902218	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0	0.0	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.0	0.0	GO:0060988	lipid tube assembly(GO:0060988)
0.0	0.0	GO:0072092	ureteric bud invasion(GO:0072092)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.0	GO:0042167	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.0	GO:0006868	glutamine transport(GO:0006868)
0.0	0.1	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.0	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.0	0.0	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.1	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.0	0.0	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.0	0.0	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0	0.7	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.1	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.1	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.0	GO:0036016	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0	0.0	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	0.0	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.1	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.0	0.0	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.0	0.0	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.0	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.0	0.1	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.0	0.0	GO:0009233	menaquinone metabolic process(GO:0009233)
0.0	0.0	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.0	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.0	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0	0.0	GO:1904430	negative regulation of t-circle formation(GO:1904430)
0.0	0.0	GO:1902993	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0	0.1	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.2	GO:0035987	endodermal cell differentiation(GO:0035987)
0.0	0.1	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.0	GO:0030397	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0	0.1	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
0.0	0.0	GO:0015888	thiamine transport(GO:0015888)
0.0	0.1	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	0.4	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.0	0.0	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.0	GO:0072318	clathrin coat disassembly(GO:0072318)
0.0	0.0	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.0	GO:0018992	germ-line sex determination(GO:0018992)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.0	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0	0.1	GO:0070417	cellular response to cold(GO:0070417)
0.0	0.1	GO:0097264	self proteolysis(GO:0097264)
0.0	0.1	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.0	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0	0.1	GO:0046113	purine nucleobase catabolic process(GO:0006145) xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110) nucleobase catabolic process(GO:0046113)
0.0	0.0	GO:0019346	homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
0.0	0.0	GO:0045794	negative regulation of cell volume(GO:0045794)
0.0	0.0	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.2	GO:2000757	negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.0	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.0	GO:0043201	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0	0.1	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.0	0.0	GO:1904417	regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.0	0.2	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.0	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.0	GO:0044838	cell quiescence(GO:0044838)
0.0	0.0	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.0	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.2	GO:0014003	oligodendrocyte development(GO:0014003)
0.0	0.2	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.1	GO:1904667	negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0	0.1	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.0	GO:0002540	leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.0	GO:0015846	polyamine transport(GO:0015846)
0.0	0.0	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
0.0	0.0	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.1	0.4	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.6	GO:0097433	dense body(GO:0097433)
0.1	0.3	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.8	GO:0016600	flotillin complex(GO:0016600)
0.1	0.2	GO:0032127	dense core granule membrane(GO:0032127)
0.1	0.3	GO:0070695	FHF complex(GO:0070695)
0.1	0.3	GO:0005638	lamin filament(GO:0005638)
0.1	0.4	GO:0043219	lateral loop(GO:0043219)
0.1	0.2	GO:0071141	SMAD protein complex(GO:0071141)
0.1	0.4	GO:0045179	apical cortex(GO:0045179)
0.1	0.4	GO:0031931	TORC1 complex(GO:0031931)
0.1	0.5	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.5	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.4	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.3	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.0	0.7	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0098651	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0	0.1	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.1	GO:0033010	paranodal junction(GO:0033010)
0.0	0.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.3	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.2	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.1	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.0	0.0	GO:1903349	omegasome membrane(GO:1903349)
0.0	0.5	GO:0005605	basal lamina(GO:0005605)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.0	GO:0032010	phagolysosome(GO:0032010)
0.0	0.4	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.2	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.0	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.2	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.1	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.6	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.1	GO:0043203	axon hillock(GO:0043203)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.1	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.1	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.1	GO:0043293	apoptosome(GO:0043293)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.0	0.1	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.0	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.3	GO:0044215	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.5	GO:0015030	Cajal body(GO:0015030)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.0	GO:1990357	terminal web(GO:1990357)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0097422	tubular endosome(GO:0097422)
0.0	0.0	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.0	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.1	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.0	0.8	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.1	GO:0070938	contractile ring(GO:0070938)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.0	GO:0001651	dense fibrillar component(GO:0001651)
0.0	0.8	GO:0005581	collagen trimer(GO:0005581)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.2	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.0	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.1	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.5	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.1	0.4	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.1	0.4	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.3	GO:0001031	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.1	0.4	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.1	0.3	GO:0004793	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1	0.4	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.1	0.3	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.3	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.1	0.7	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.1	0.3	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.1	0.2	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.1	0.2	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1	0.3	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.3	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.1	0.2	GO:2001069	glycogen binding(GO:2001069)
0.1	0.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.4	GO:0008199	ferric iron binding(GO:0008199)
0.1	0.2	GO:0048408	epidermal growth factor binding(GO:0048408)
0.1	0.2	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	0.2	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1	0.2	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	0.4	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1	0.2	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.2	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.1	0.5	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.1	0.2	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.1	0.5	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1	0.2	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.5	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.4	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.2	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.0	0.7	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.7	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:1990188	euchromatin binding(GO:1990188)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.4	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.2	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0	0.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.1	GO:0019862	IgA binding(GO:0019862)
0.0	0.2	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.2	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.2	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.3	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.4	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0051373	FATZ binding(GO:0051373)
0.0	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.1	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.4	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0008506	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.2	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.1	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.0	0.5	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.4	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0030984	kininogen binding(GO:0030984)
0.0	0.1	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.3	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.1	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.3	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.0	GO:0070905	serine binding(GO:0070905)
0.0	0.1	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.0	0.1	GO:0000150	recombinase activity(GO:0000150)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.3	GO:0070034	telomerase RNA binding(GO:0070034)
0.0	0.1	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.0	0.0	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.1	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0	0.0	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.6	GO:0052771	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.3	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.2	GO:0001055	RNA polymerase II activity(GO:0001055)
0.0	0.1	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.2	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0	0.1	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.0	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.1	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.0	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.1	GO:0009378	four-way junction helicase activity(GO:0009378)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.8	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.1	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.1	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.2	GO:0005536	glucose binding(GO:0005536)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.0	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.0	GO:0052744	phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0	0.0	GO:0042731	PH domain binding(GO:0042731)
0.0	0.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0001163	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.0	0.0	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.1	GO:0004673	protein histidine kinase activity(GO:0004673)
0.0	0.1	GO:0034838	enoyl-[acyl-carrier-protein] reductase activity(GO:0016631) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity(GO:0018498) cis-2,3-dihydrodiol DDT dehydrogenase activity(GO:0018499) trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity(GO:0018500) cis-chlorobenzene dihydrodiol dehydrogenase activity(GO:0018501) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity(GO:0018502) trans-1,2-dihydrodiolphenanthrene dehydrogenase activity(GO:0018503) 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity(GO:0034790) benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity(GO:0034805) benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity(GO:0034809) citronellyl-CoA dehydrogenase activity(GO:0034824) menthone dehydrogenase activity(GO:0034838) phthalate 3,4-cis-dihydrodiol dehydrogenase activity(GO:0034912) cinnamate reductase activity(GO:0043786) NADPH-dependent curcumin reductase activity(GO:0052849) NADPH-dependent dihydrocurcumin reductase activity(GO:0052850)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0070883	pre-miRNA binding(GO:0070883)
0.0	0.4	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.0	0.0	GO:0045503	dynein light chain binding(GO:0045503)
0.0	0.2	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.6	GO:0005080	protein kinase C binding(GO:0005080)
0.0	0.0	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	0.0	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.1	GO:0008556	potassium-transporting ATPase activity(GO:0008556)
0.0	0.1	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.0	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.0	0.0	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0	0.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.1	GO:0016726	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0	0.2	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0010181	FMN binding(GO:0010181)
0.0	0.1	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.2	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.4	GO:0097110	scaffold protein binding(GO:0097110)
0.0	0.1	GO:0031559	oxidosqualene cyclase activity(GO:0031559)
0.0	0.2	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.0	GO:2001070	starch binding(GO:2001070)
0.0	0.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.1	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.0	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.0	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.7	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.9	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.0	ST GAQ PATHWAY	G alpha q Pathway
0.0	1.0	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.4	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.4	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.7	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.3	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.5	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.5	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.3	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.4	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.0	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.3	PID EPHA FWDPATHWAY	EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	1.0	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.7	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.0	REACTOME PI 3K CASCADE	Genes involved in PI-3K cascade
0.0	0.4	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.5	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.4	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.4	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.5	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.2	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.3	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.0	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.0	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.3	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.3	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.0	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.0	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.2	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes