Project
ENCSR904DTN: DNase-seq of mouse liver in constant darkness
Navigation
Downloads
Logo

Results for Egr4

Z-value: 1.00

Motif logo

logo of

Transcription factors associated with Egr4

Gene Symbol Gene ID Gene Info
Egr4
ENSMUSG00000071341.3 early growth response 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_85510591_85510748Egr429200.1755430.424.1e-01Click!

Activity of the Egr4 motif across conditions

Conditions sorted by the z-value of the Egr4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr8_125569857_125570144 4.42 Sipa1l2
 signal-induced proliferation-associated 1 like 2
 192
 0.96
chr9_48984872_48985421 3.34 Usp28
 ubiquitin specific peptidase 28
 229
 0.92
chrX_12761746_12762400 1.17 Med14
 mediator complex subunit 14
 0
 0.73
chr11_75173089_75173918 1.13 Mir212
 microRNA 212
 115
 0.56
chr14_120830490_120830770 0.93 Gm9391
 predicted gene 9391
 3472
 0.2
chr9_89199094_89199252 0.90 Bcl2a1b
 B cell leukemia/lymphoma 2 related protein A1b
 36
 0.71
chr10_80343063_80343448 0.87 Adamtsl5
 ADAMTS-like 5
 1983
 0.12
chrX_9272438_9272819 0.84 Xk
 X-linked Kx blood group
 128
 0.94
chr1_182763696_182764002 0.82 Susd4
 sushi domain containing 4
 11
 0.98
chr9_107986066_107986266 0.80 Inka1
 inka box actin regulator 1
 287
 0.67
chr15_96494191_96494357 0.71 Gm41392
 predicted gene, 41392
 303
 0.91
chr12_76370132_76370629 0.71 Zbtb1
 zinc finger and BTB domain containing 1
 114
 0.89
chr19_46328692_46329074 0.69 Fbxl15
 F-box and leucine-rich repeat protein 15
 696
 0.41
chr8_122324060_122324293 0.68 Zfpm1
 zinc finger protein, multitype 1
 9522
 0.13
chrX_123103386_123103718 0.67 Cldn34c1
 claudin 34C1
 2
 0.98
chr3_145924039_145924997 0.62 Bcl10
 B cell leukemia/lymphoma 10
 161
 0.95
chr5_142938438_142938600 0.57 Fscn1
 fascin actin-bundling protein 1
 21824
 0.13
chr6_85431886_85432060 0.56 Smyd5
 SET and MYND domain containing 5
 16
 0.96
chr17_24470568_24470947 0.55 Pgp
 phosphoglycolate phosphatase
 322
 0.51
chr1_36939852_36940044 0.55 Tmem131
 transmembrane protein 131
 126
 0.95
chr11_97883591_97883758 0.55 Fbxo47
 F-box protein 47
 480
 0.58
chr10_60346558_60346709 0.55 Vsir
 V-set immunoregulatory receptor
 218
 0.94
chr3_108257311_108257615 0.54 1700010K24Rik
 RIKEN cDNA 1700010K24 gene
 478
 0.42
chr17_35667522_35667701 0.54 Vars2
 valyl-tRNA synthetase 2, mitochondrial
 19
 0.92
chr6_128799156_128799331 0.53 Klrb1c
 killer cell lectin-like receptor subfamily B member 1C
 10028
 0.1
chr10_79897700_79897893 0.53 Med16
 mediator complex subunit 16
 1889
 0.11
chr2_124609977_124610547 0.53 Sema6d
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
 34
 0.99
chr15_97908200_97908485 0.52 Vdr
 vitamin D (1,25-dihydroxyvitamin D3) receptor
 32
 0.98
chr2_156008335_156008486 0.51 Ergic3
 ERGIC and golgi 3
 187
 0.72
chr1_153424966_153425246 0.51 Shcbp1l
 Shc SH2-domain binding protein 1-like
 56
 0.96
chr3_52267780_52268128 0.49 Foxo1
 forkhead box O1
 382
 0.75
chr7_25395891_25396191 0.49 Lipe
 lipase, hormone sensitive
 338
 0.61
chr9_20521562_20521965 0.49 Zfp266
 zinc finger protein 266
 346
 0.81
chr10_17948008_17948419 0.48 Heca
 hdc homolog, cell cycle regulator
 146
 0.97
chr2_155390028_155390312 0.47 Ncoa6
 nuclear receptor coactivator 6
 6656
 0.14
chr17_34958907_34959139 0.46 Hspa1b
 heat shock protein 1B
 215
 0.75
chr14_50924662_50925001 0.46 Osgep
 O-sialoglycoprotein endopeptidase
 1
 0.62
chr2_27284271_27284473 0.46 Vav2
 vav 2 oncogene
 5493
 0.18
chr11_75170209_75170498 0.45 Hic1
 hypermethylated in cancer 1
 834
 0.37
chr15_79927724_79927894 0.45 Cbx7
 chromobox 7
 4707
 0.14
chr1_132007861_132008160 0.45 Elk4
 ELK4, member of ETS oncogene family
 89
 0.96
chr13_58157546_58157700 0.44 Idnk
 idnK gluconokinase homolog (E. coli)
 26
 0.51
chr16_17928117_17928461 0.44 Slc25a1
 solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
 70
 0.94
chr1_130715772_130716198 0.43 Pfkfb2
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
 171
 0.49
chr6_48086500_48086790 0.42 Zfp746
 zinc finger protein 746
 52
 0.97
chr11_61684235_61684526 0.42 Fam83g
 family with sequence similarity 83, member G
 39
 0.97
chr4_141060479_141060918 0.42 Crocc
 ciliary rootlet coiled-coil, rootletin
 148
 0.92
chr19_44393747_44393961 0.41 Scd1
 stearoyl-Coenzyme A desaturase 1
 12836
 0.14
chr9_55283614_55283814 0.40 Nrg4
 neuregulin 4
 89
 0.97
chr7_18990506_18990869 0.40 Mypop
 Myb-related transcription factor, partner of profilin
 558
 0.49
chr7_64048693_64048852 0.40 Gm45054
 predicted gene 45054
 7946
 0.16
chr9_88731798_88731969 0.40 Bcl2a1d
 B cell leukemia/lymphoma 2 related protein A1d
 31
 0.59
chr14_65667090_65667241 0.40 Scara5
 scavenger receptor class A, member 5
 728
 0.73
chr4_129618572_129618944 0.40 Iqcc
 IQ motif containing C
 318
 0.73
chr4_119138309_119138481 0.39 Gm12868
 predicted gene 12868
 406
 0.71
chr17_26138333_26138708 0.39 Axin1
 axin 1
 168
 0.88
chr3_55112219_55112827 0.38 Spg20
 spastic paraplegia 20, spartin (Troyer syndrome) homolog (human)
 73
 0.97
chr6_136449342_136449720 0.38 Gm25882
 predicted gene, 25882
 31719
 0.1
chr17_34971805_34972034 0.37 Hspa1a
 heat shock protein 1A
 237
 0.66
chr8_75213035_75213232 0.37 Rasd2
 RASD family, member 2
 811
 0.58
chr15_8168911_8169078 0.37 Cplane1
 ciliogenesis and planar polarity effector 1
 112
 0.97
chr2_180589339_180589504 0.37 Ogfr
 opioid growth factor receptor
 41
 0.96
chr15_88832888_88833102 0.37 Gm23144
 predicted gene, 23144
 2305
 0.21
chr10_80577672_80578424 0.37 Klf16
 Kruppel-like factor 16
 727
 0.41
chr4_106463187_106463359 0.36 Pcsk9
 proprotein convertase subtilisin/kexin type 9
 1056
 0.45
chr7_127876515_127876679 0.36 Zfp668
 zinc finger protein 668
 180
 0.49
chr5_140389137_140389453 0.36 Snx8
 sorting nexin 8
 33
 0.97
chr6_124965028_124965351 0.36 Cops7a
 COP9 signalosome subunit 7A
 18
 0.92
chr10_77902990_77903176 0.36 Lrrc3
 leucine rich repeat containing 3
 547
 0.54
chr17_35186094_35186252 0.36 Lst1
 leukocyte specific transcript 1
 2266
 0.07
chr8_70792935_70793116 0.36 Mast3
 microtubule associated serine/threonine kinase 3
 588
 0.47
chr4_47352960_47353255 0.36 Tgfbr1
 transforming growth factor, beta receptor I
 115
 0.97
chr10_4432270_4432710 0.35 Armt1
 acidic residue methyltransferase 1
 23
 0.58
chr4_101647910_101648061 0.35 Leprot
 leptin receptor overlapping transcript
 192
 0.96
chr4_149517672_149517903 0.35 Ctnnbip1
 catenin beta interacting protein 1
 449
 0.45
chr3_145790177_145790690 0.35 Ddah1
 dimethylarginine dimethylaminohydrolase 1
 20046
 0.19
chr1_183345405_183345565 0.34 Mia3
 melanoma inhibitory activity 3
 29
 0.97
chr18_35272122_35272298 0.34 Gm50146
 predicted gene, 50146
 8181
 0.17
chr10_81167707_81168009 0.34 Pias4
 protein inhibitor of activated STAT 4
 65
 0.92
chr7_19404092_19404290 0.33 Klc3
 kinesin light chain 3
 87
 0.85
chr19_28834565_28834716 0.32 Slc1a1
 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
 409
 0.82
chr18_46597468_46597778 0.32 Eif1a
 eukaryotic translation initiation factor 1A
 78
 0.5
chr13_32802244_32802687 0.32 Wrnip1
 Werner helicase interacting protein 1
 349
 0.49
chr11_71018794_71019067 0.32 Derl2
 Der1-like domain family, member 2
 282
 0.7
chr18_5819758_5819934 0.32 Zeb1
 zinc finger E-box binding homeobox 1
 88765
 0.08
chr1_133609970_133610131 0.31 Snrpe
 small nuclear ribonucleoprotein E
 3
 0.97
chr5_53995353_53995770 0.31 Stim2
 stromal interaction molecule 2
 2938
 0.33
chr5_47983016_47983183 0.31 Slit2
 slit guidance ligand 2
 39
 0.97
chr16_4913847_4914003 0.31 Mgrn1
 mahogunin, ring finger 1
 714
 0.53
chr15_76576499_76576688 0.31 Adck5
 aarF domain containing kinase 5
 119
 0.88
chr7_19629444_19629613 0.30 Relb
 avian reticuloendotheliosis viral (v-rel) oncogene related B
 90
 0.93
chr7_80689221_80689503 0.30 Crtc3
 CREB regulated transcription coactivator 3
 485
 0.79
chr4_135433737_135434028 0.30 Rcan3
 regulator of calcineurin 3
 29
 0.95
chr11_96075628_96076164 0.30 Atp5g1
 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)
 226
 0.86
chr11_98005250_98005423 0.30 Cacnb1
 calcium channel, voltage-dependent, beta 1 subunit
 7215
 0.09
chr17_31386046_31386544 0.29 Pde9a
 phosphodiesterase 9A
 1
 0.97
chr12_69680699_69681071 0.29 Sos2
 SOS Ras/Rho guanine nucleotide exchange factor 2
 742
 0.62
chr18_35598506_35598676 0.29 Gm50163
 predicted gene, 50163
 18
 0.49
chr5_98329132_98329560 0.29 Cfap299
 cilia and flagella associated protein 299
 5
 0.98
chr5_136244667_136245141 0.29 Sh2b2
 SH2B adaptor protein 2
 1
 0.97
chr1_179668115_179668496 0.29 Sccpdh
 saccharopine dehydrogenase (putative)
 45
 0.98
chr7_29211431_29211967 0.29 Catsperg1
 cation channel sperm associated auxiliary subunit gamma 1
 204
 0.86
chr6_137386444_137386618 0.29 Ptpro
 protein tyrosine phosphatase, receptor type, O
 24190
 0.21
chr5_99252774_99253080 0.29 Rasgef1b
 RasGEF domain family, member 1B
 0
 0.98
chr9_50659707_50659907 0.29 Dlat
 dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
 27
 0.96
chr12_102439744_102439900 0.29 Lgmn
 legumain
 9
 0.98
chr10_108435314_108435492 0.28 Gm36283
 predicted gene, 36283
 1262
 0.46
chr17_35978974_35979125 0.28 Prr3
 proline-rich polypeptide 3
 78
 0.87
chr7_38084831_38085137 0.28 Ccne1
 cyclin E1
 14385
 0.15
chr12_8674756_8674907 0.27 Pum2
 pumilio RNA-binding family member 2
 66
 0.98
chr14_45657978_45658304 0.27 Ddhd1
 DDHD domain containing 1
 1
 0.56
chr6_128760422_128760580 0.27 Gm43907
 predicted gene, 43907
 15857
 0.1
chr4_76360819_76360981 0.27 Ptprd
 protein tyrosine phosphatase, receptor type, D
 16657
 0.23
chr7_80370643_80370981 0.27 Man2a2
 mannosidase 2, alpha 2
 46
 0.95
chr6_39725291_39725442 0.27 Braf
 Braf transforming gene
 97
 0.97
chr8_94876377_94876534 0.27 Dok4
 docking protein 4
 125
 0.93
chr19_61226929_61227456 0.27 Csf2ra
 colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
 44
 0.96
chr13_55105166_55105330 0.27 Zfp346
 zinc finger protein 346
 63
 0.96
chr12_5375671_5375936 0.27 2810032G03Rik
 RIKEN cDNA 2810032G03 gene
 67
 0.57
chr11_95337319_95337527 0.26 Gm11521
 predicted gene 11521
 15
 0.86
chr17_28523067_28523337 0.26 Gm20109
 predicted gene, 20109
 54
 0.53
chr13_34874226_34874546 0.26 Prpf4b
 pre-mRNA processing factor 4B
 916
 0.34
chr4_63216606_63216811 0.26 Col27a1
 collagen, type XXVII, alpha 1
 1273
 0.43
chr12_17691350_17691514 0.26 Hpcal1
 hippocalcin-like 1
 576
 0.8
chr18_67768082_67768255 0.26 Gm26910
 predicted gene, 26910
 6689
 0.15
chr12_110446490_110446665 0.26 Ppp2r5c
 protein phosphatase 2, regulatory subunit B', gamma
 543
 0.76
chr17_29848916_29849085 0.26 Mdga1
 MAM domain containing glycosylphosphatidylinositol anchor 1
 1541
 0.36
chr4_142015030_142015185 0.25 Fhad1
 forkhead-associated (FHA) phosphopeptide binding domain 1
 25
 0.96
chr7_80055730_80056046 0.25 Gm44951
 predicted gene 44951
 19183
 0.1
chr2_163750130_163750300 0.25 Ada
 adenosine deaminase
 24
 0.98
chr3_58692272_58692637 0.25 Siah2
 siah E3 ubiquitin protein ligase 2
 54
 0.6
chr2_169929567_169929785 0.25 AY702102
 cDNA sequence AY702102
 33311
 0.2
chr18_46959082_46959408 0.25 Commd10
 COMM domain containing 10
 365
 0.59
chr11_8663817_8664182 0.25 Tns3
 tensin 3
 536
 0.87
chr17_6742196_6742355 0.25 Ezr
 ezrin
 546
 0.75
chr17_56124312_56124572 0.24 Lrg1
 leucine-rich alpha-2-glycoprotein 1
 2441
 0.13
chr13_108158589_108158750 0.24 Ndufaf2
 NADH:ubiquinone oxidoreductase complex assembly factor 2
 46
 0.51
chr3_138222614_138222780 0.24 Adh7
 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
 1226
 0.36
chr15_97964312_97964525 0.24 Tmem106c
 transmembrane protein 106C
 148
 0.95
chr1_67141728_67142108 0.24 Cps1
 carbamoyl-phosphate synthetase 1
 18892
 0.22
chr8_3676646_3677297 0.24 Gm45231
 predicted gene 45231
 17
 0.85
chr4_129600776_129601168 0.24 Tmem234
 transmembrane protein 234
 11
 0.81
chr4_151801848_151802061 0.23 Camta1
 calmodulin binding transcription activator 1
 59696
 0.12
chr4_19699207_19699375 0.23 Wwp1
 WW domain containing E3 ubiquitin protein ligase 1
 9702
 0.21
chr18_80046692_80046991 0.23 Pard6g
 par-6 family cell polarity regulator gamma
 49
 0.94
chr6_90543682_90543913 0.23 Aldh1l1
 aldehyde dehydrogenase 1 family, member L1
 6992
 0.14
chr9_35175976_35176147 0.23 Dcps
 decapping enzyme, scavenger
 0
 0.96
chr2_160731435_160731699 0.23 Plcg1
 phospholipase C, gamma 1
 132
 0.96
chr9_72132987_72133379 0.23 Gm7863
 predicted gene 7863
 4596
 0.13
chr7_4470400_4470562 0.23 Gm15494
 predicted gene 15494
 768
 0.4
chr5_99630204_99630355 0.23 4930405H06Rik
 RIKEN cDNA 4930405H06 gene
 4443
 0.18
chr17_56074581_56074743 0.23 Ubxn6
 UBX domain protein 6
 115
 0.92
chr8_93257060_93257211 0.22 Ces1f
 carboxylesterase 1F
 1604
 0.3
chr7_19573353_19573652 0.22 Gemin7
 gem nuclear organelle associated protein 7
 117
 0.92
chr19_59588162_59588313 0.22 Gm18161
 predicted gene, 18161
 47786
 0.13
chr15_55043394_55043818 0.22 Taf2
 TATA-box binding protein associated factor 2
 2560
 0.24
chr10_75407266_75407457 0.22 Upb1
 ureidopropionase, beta
 403
 0.84
chr4_53384770_53385134 0.22 Gm12496
 predicted gene 12496
 19078
 0.2
chr8_92355755_92356018 0.22 Crnde
 colorectal neoplasia differentially expressed (non-protein coding)
 5
 0.97
chr11_121061638_121061789 0.22 Sectm1b
 secreted and transmembrane 1B
 1590
 0.2
chr3_94363287_94363473 0.22 C2cd4d
 C2 calcium-dependent domain containing 4D
 877
 0.31
chr2_33370578_33371002 0.22 Ralgps1
 Ral GEF with PH domain and SH3 binding motif 1
 639
 0.68
chrX_105079895_105080067 0.22 Pbdc1
 polysaccharide biosynthesis domain containing 1
 206
 0.68
chr17_69383732_69384083 0.22 Zbtb14
 zinc finger and BTB domain containing 14
 67
 0.79
chr15_28024715_28025200 0.22 Trio
 triple functional domain (PTPRF interacting)
 3
 0.98
chr17_83350686_83350964 0.22 Eml4
 echinoderm microtubule associated protein like 4
 106
 0.98
chr10_85102143_85102819 0.21 Fhl4
 four and a half LIM domains 4
 14
 0.65
chr5_100039849_100040017 0.21 Enoph1
 enolase-phosphatase 1
 52
 0.77
chr13_119597768_119597952 0.21 Tmem267
 transmembrane protein 267
 8790
 0.14
chr1_181144140_181144500 0.21 Nvl
 nuclear VCP-like
 116
 0.78
chr18_32163467_32163952 0.21 Map3k2
 mitogen-activated protein kinase kinase kinase 2
 513
 0.7
chr10_128232239_128232414 0.21 Timeless
 timeless circadian clock 1
 192
 0.85
chr6_117168297_117168684 0.21 Cxcl12
 chemokine (C-X-C motif) ligand 12
 45
 0.97
chrX_134058988_134059612 0.21 Cstf2
 cleavage stimulation factor, 3' pre-RNA subunit 2
 11
 0.97
chr6_47758577_47758728 0.20 Rpl31-ps7
 ribosomal protein L31, pseudogene 7
 27722
 0.12
chr12_54734831_54734991 0.20 Gm24305
 predicted gene, 24305
 193
 0.83
chr2_3702714_3702883 0.20 Fam107b
 family with sequence similarity 107, member B
 1215
 0.43
chr7_27361465_27361626 0.20 Gm20479
 predicted gene 20479
 4126
 0.13
chr7_16028493_16028658 0.20 Bicra
 BRD4 interacting chromatin remodeling complex associated protein
 19346
 0.12
chr19_41482156_41482948 0.20 Lcor
 ligand dependent nuclear receptor corepressor
 85
 0.98
chr9_30137436_30137587 0.20 Gm47677
 predicted gene, 47677
 30064
 0.22
chr3_30855609_30856108 0.20 Gpr160
 G protein-coupled receptor 160
 92
 0.96
chr12_54713945_54714104 0.20 Gm23804
 predicted gene, 23804
 194
 0.82
chr11_117341816_117342087 0.19 Septin9
 septin 9
 9523
 0.19
chr17_35254463_35254614 0.19 Mir8094
 microRNA 8094
 3249
 0.07
chr12_98628007_98628201 0.19 Spata7
 spermatogenesis associated 7
 53
 0.96
chr12_102308562_102308753 0.19 Rin3
 Ras and Rab interactor 3
 25016
 0.19
chr6_88198537_88198710 0.19 Gata2
 GATA binding protein 2
 289
 0.86
chr7_24399784_24400299 0.19 Smg9
 smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)
 120
 0.92
chr5_3927775_3928123 0.19 Akap9
 A kinase (PRKA) anchor protein (yotiao) 9
 105
 0.96
chr11_65787387_65787891 0.19 Map2k4
 mitogen-activated protein kinase kinase 4
 646
 0.74
chr9_114731036_114731195 0.19 Cmtm6
 CKLF-like MARVEL transmembrane domain containing 6
 1
 0.97
chr16_32673286_32673709 0.19 Tnk2
 tyrosine kinase, non-receptor, 2
 298
 0.87
chr6_47772904_47773093 0.19 Rpl31-ps7
 ribosomal protein L31, pseudogene 7
 13376
 0.13
chr6_58610800_58610960 0.19 Abcg2
 ATP binding cassette subfamily G member 2 (Junior blood group)
 14209
 0.2
chr8_117673801_117673966 0.18 Sdr42e1
 short chain dehydrogenase/reductase family 42E, member 1
 194
 0.92
chr4_97776562_97776976 0.18 Nfia
 nuclear factor I/A
 839
 0.51
chr6_47664591_47664742 0.18 Gm44141
 predicted gene, 44141
 29369
 0.16
chr11_22376520_22376679 0.18 Rpsa-ps3
 ribosomal protein SA, pseudogene 3
 9693
 0.21
chr15_82987815_82987989 0.18 Tcf20
 transcription factor 20
 30
 0.53

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Egr4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0002572 pro-T cell differentiation(GO:0002572)
0.2 0.8 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.2 0.5 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.2 0.5 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.2 0.8 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.2 0.5 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.2 0.8 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.4 GO:0048696 regulation of collateral sprouting in absence of injury(GO:0048696)
0.1 0.4 GO:0048320 axial mesoderm formation(GO:0048320)
0.1 0.5 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.1 0.3 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.3 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.7 GO:0008354 germ cell migration(GO:0008354)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:0000101 sulfur amino acid transport(GO:0000101)
0.1 0.2 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.3 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1 0.2 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725)
0.1 3.1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.3 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 1.2 GO:0014041 regulation of neuron maturation(GO:0014041)
0.1 0.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.1 0.3 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.2 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.3 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.2 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.2 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.3 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 0.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.3 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0048550 negative regulation of pinocytosis(GO:0048550)
0.0 0.5 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.9 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0060375 mast cell differentiation(GO:0060374) regulation of mast cell differentiation(GO:0060375)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.2 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.2 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.0 0.3 GO:0010388 cullin deneddylation(GO:0010388)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.2 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.2 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 0.1 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.1 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.2 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 0.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0 0.1 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0097460 ferrous iron import into cell(GO:0097460)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.5 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.1 GO:0015781 nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.0 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 3.8 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.1 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 1.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.0 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.0 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0 0.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.2 GO:0002467 germinal center formation(GO:0002467)
0.0 0.1 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.0 GO:0060178 regulation of exocyst localization(GO:0060178)
0.0 0.0 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.1 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.0 0.0 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.0 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.0 0.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.1 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.1 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.0 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.2 GO:1900271 regulation of long-term synaptic potentiation(GO:1900271)
0.0 0.0 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.2 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.0 GO:1900060 negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.0 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.0 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.0 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.0 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.0 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.0 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.0 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.0 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.0 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085) negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0 0.0 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.0 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0070847 core mediator complex(GO:0070847)
0.1 0.5 GO:0001651 dense fibrillar component(GO:0001651)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.3 GO:0044393 microspike(GO:0044393)
0.1 0.7 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.5 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.3 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0030313 cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0 0.2 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.0 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.0 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.2 0.5 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.4 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.9 GO:0051400 BH domain binding(GO:0051400)
0.1 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.6 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 3.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.5 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 3.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0019145 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.1 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.4 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.0 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.0 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.1 GO:0015189 arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.0 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.9 GO:0016205 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0052859 dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.0 0.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.0 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.9 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.0 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.0 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.0 GO:0004035 alkaline phosphatase activity(GO:0004035)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.8 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.0 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis