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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Emx1_Emx2

Z-value: 2.08

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Transcription factors associated with Emx1_Emx2

Gene Symbol	Gene ID	Gene Info
Emx1 Ensembl NCBI MGI UniProt	ENSMUSG00000033726.8	empty spiracles homeobox 1
Emx2 Ensembl NCBI MGI UniProt	ENSMUSG00000043969.4	empty spiracles homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr6_85224947_85225098	Emx1	31503	0.107317	-0.74	9.3e-02	Click!
chr6_85224756_85224918	Emx1	31318	0.107580	-0.61	2.0e-01	Click!
chr6_85180186_85180346	Emx1	7172	0.111974	-0.54	2.7e-01	Click!
chr6_85209360_85209527	Emx1	15924	0.124911	-0.06	9.1e-01	Click!
chr19_59455726_59455909	Emx2	2555	0.225411	-0.65	1.6e-01	Click!
chr19_59454303_59454483	Emx2	3979	0.189560	-0.34	5.1e-01	Click!
chr19_59460494_59460645	Emx2	1050	0.436799	-0.23	6.6e-01	Click!

Activity of the Emx1_Emx2 motif across conditions

Conditions sorted by the z-value of the Emx1_Emx2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr6_121890040_121890777	1.50	Mug1	murinoglobulin 1	4831	0.21
chr15_31279226_31279377	1.20	Gm49296	predicted gene, 49296	2788	0.19
chr11_67549406_67549557	1.10	Gas7	growth arrest specific 7	2028	0.38
chr11_7201515_7201726	1.05	Igfbp1	insulin-like growth factor binding protein 1	3838	0.2
chr1_119253363_119253514	1.04	Gm3508	predicted gene 3508	10685	0.22
chr11_112218841_112219019	1.01	Gm11680	predicted gene 11680	111492	0.07
chr1_131068447_131068615	0.98	Mapkapk2	MAP kinase-activated protein kinase 2	3995	0.16
chr5_89033271_89033463	0.97	Slc4a4	solute carrier family 4 (anion exchanger), member 4	5275	0.32
chr9_65296934_65297096	0.96	Gm16218	predicted gene 16218	904	0.39
chr1_106813159_106813457	0.96	Vps4b	vacuolar protein sorting 4B	16580	0.18
chr3_119194156_119194307	0.94	Gm43410	predicted gene 43410	325987	0.01
chr5_118292276_118292427	0.93	Gm25076	predicted gene, 25076	25902	0.16
chr2_136986571_136986744	0.91	Slx4ip	SLX4 interacting protein	81114	0.08
chr19_43971247_43971535	0.86	Cpn1	carboxypeptidase N, polypeptide 1	2698	0.21
chr5_146844458_146844622	0.81	Rasl11a	RAS-like, family 11, member A	531	0.68
chr11_50733265_50733435	0.74	Gm12200	predicted gene 12200	7806	0.16
chr13_117745874_117746186	0.73	4933413L06Rik	RIKEN cDNA 4933413L06 gene	26019	0.26
chr3_83023876_83024027	0.68	Fga	fibrinogen alpha chain	2125	0.24
chr19_30093178_30093359	0.68	Uhrf2	ubiquitin-like, containing PHD and RING finger domains 2	1307	0.48
chr15_26379044_26379231	0.68	Marchf11	membrane associated ring-CH-type finger 11	8582	0.31
chr7_138547394_138547558	0.67	4930543N07Rik	RIKEN cDNA 4930543N07 gene	6754	0.29
chr8_71405347_71405498	0.66	Ankle1	ankyrin repeat and LEM domain containing 1	588	0.54
chr7_27129962_27130129	0.66	Gm15883	predicted gene 15883	629	0.5
chr6_137723997_137724165	0.65	Strap	serine/threonine kinase receptor associated protein	10997	0.22
chr1_89898377_89898561	0.64	Gbx2	gastrulation brain homeobox 2	30716	0.16
chr16_24394028_24394581	0.64	Lpp	LIM domain containing preferred translocation partner in lipoma	566	0.73
chr4_115607059_115607329	0.63	Cyp4a32	cytochrome P450, family 4, subfamily a, polypeptide 32	6219	0.14
chr16_10952807_10952965	0.61	Gm26268	predicted gene, 26268	12838	0.11
chr5_150228070_150228236	0.61	Gm36378	predicted gene, 36378	15710	0.19
chr16_35743238_35743408	0.61	Gm25967	predicted gene, 25967	21090	0.13
chr5_89322164_89322355	0.61	Gc	vitamin D binding protein	113369	0.07
chr13_43232894_43233157	0.60	Tbc1d7	TBC1 domain family, member 7	61524	0.1
chr14_50997940_50998134	0.59	Gm49038	predicted gene, 49038	962	0.33
chr7_104995535_104995703	0.59	Olfr672	olfactory receptor 672	1283	0.2
chr16_35903108_35903259	0.59	Gm41467	predicted gene, 41467	11769	0.11
chr5_135776480_135776870	0.59	Styxl1	serine/threonine/tyrosine interacting-like 1	1563	0.22
chr7_127008308_127008486	0.58	Mvp	major vault protein	3468	0.07
chr1_39133288_39133558	0.58	Gm37091	predicted gene, 37091	50085	0.11
chr14_45993530_45993681	0.58	Gm49192	predicted gene, 49192	2568	0.27
chr4_120076409_120076580	0.57	AL607142.1	novel protein	11498	0.22
chr6_128520429_128520580	0.57	Pzp	PZP, alpha-2-macroglobulin like	6199	0.1
chr2_172862507_172862658	0.56	Gm22773	predicted gene, 22773	1759	0.43
chr3_57424731_57424906	0.55	Tm4sf4	transmembrane 4 superfamily member 4	496	0.83
chr7_117781072_117781236	0.55	Gm24063	predicted gene, 24063	4360	0.35
chr5_105826898_105827072	0.55	Lrrc8d	leucine rich repeat containing 8D	2474	0.21
chr6_145345231_145345418	0.53	Gm23498	predicted gene, 23498	21534	0.11
chr2_75564827_75565114	0.53	Gm13655	predicted gene 13655	68412	0.08
chr11_46019744_46019943	0.53	Gm12165	predicted gene 12165	16597	0.13
chr18_24652159_24652325	0.52	Mocos	molybdenum cofactor sulfurase	1449	0.36
chr12_118887325_118887612	0.52	Abcb5	ATP-binding cassette, sub-family B (MDR/TAP), member 5	3291	0.3
chr3_50989485_50989700	0.52	Gm37209	predicted gene, 37209	10781	0.22
chr18_21372400_21372792	0.51	Gm22886	predicted gene, 22886	8335	0.2
chr18_60681229_60681400	0.51	Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	15758	0.16
chr3_121272792_121272948	0.50	Gm30517	predicted gene, 30517	4654	0.16
chr5_43224947_43225116	0.50	Cpeb2	cytoplasmic polyadenylation element binding protein 2	8139	0.16
chr2_132682597_132683135	0.49	Shld1	shieldin complex subunit 1	4065	0.13
chr14_88424431_88424582	0.49	Gm48930	predicted gene, 48930	8481	0.19
chr4_136501774_136501925	0.49	Luzp1	leucine zipper protein 1	19546	0.14
chr19_36677883_36678283	0.48	Hectd2os	Hectd2, opposite strand	11190	0.23
chr3_94338287_94338715	0.48	Gm43743	predicted gene 43743	3169	0.1
chr11_31861652_31861810	0.48	Cpeb4	cytoplasmic polyadenylation element binding protein 4	10480	0.19
chr5_88918674_88918881	0.48	Slc4a4	solute carrier family 4 (anion exchanger), member 4	15755	0.23
chr9_43545693_43545878	0.48	Gm36855	predicted gene, 36855	24781	0.17
chr3_28021286_28021536	0.48	Pld1	phospholipase D1	9851	0.28
chr17_12417364_12417701	0.47	Plg	plasminogen	38873	0.12
chr17_80073738_80073889	0.47	Hnrnpll	heterogeneous nuclear ribonucleoprotein L-like	11479	0.14
chr17_84037207_84037358	0.47	Gm49967	predicted gene, 49967	392	0.78
chr6_27826271_27826449	0.46	Mir592	microRNA 592	110390	0.07
chr11_106583145_106583311	0.46	Tex2	testis expressed gene 2	2628	0.28
chr3_153840565_153840726	0.46	Asb17	ankyrin repeat and SOCS box-containing 17	3564	0.13
chr4_97013643_97013815	0.46	Gm27521	predicted gene, 27521	96709	0.08
chr13_24950116_24950267	0.46	Gpld1	glycosylphosphatidylinositol specific phospholipase D1	5663	0.14
chr18_47313271_47313422	0.46	Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	19980	0.21
chr12_7920749_7920967	0.46	Gm18387	predicted gene, 18387	23285	0.15
chr17_13821827_13822235	0.45	Afdn	afadin, adherens junction formation factor	28931	0.14
chr15_59291383_59291534	0.45	Zfp572	zinc finger protein 572	15490	0.14
chrX_108621044_108621195	0.45	Gm379	predicted gene 379	43336	0.19
chr13_43500025_43500247	0.45	Gm47683	predicted gene, 47683	31	0.97
chr11_86681158_86681454	0.45	Vmp1	vacuole membrane protein 1	2515	0.22
chr5_126565776_126566015	0.45	Gm24839	predicted gene, 24839	51914	0.14
chr2_126562513_126562799	0.45	Slc27a2	solute carrier family 27 (fatty acid transporter), member 2	2104	0.32
chr8_34442456_34442662	0.45	Gm45349	predicted gene 45349	30436	0.14
chr7_128524976_128525130	0.45	Bag3	BCL2-associated athanogene 3	1437	0.29
chr5_145989518_145989698	0.44	Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	2035	0.23
chr4_63738674_63738850	0.44	Tnfsf15	tumor necrosis factor (ligand) superfamily, member 15	6351	0.22
chr7_79907099_79907250	0.44	Gm26646	predicted gene, 26646	9763	0.1
chr3_83004838_83005211	0.44	Fgg	fibrinogen gamma chain	2700	0.2
chr11_64844149_64844351	0.44	Gm12292	predicted gene 12292	497	0.87
chr10_56500437_56500624	0.43	Gm9118	predicted gene 9118	3189	0.31
chr14_73401494_73401664	0.43	Itm2b	integral membrane protein 2B	16290	0.19
chr7_37190411_37190586	0.43	Gm28075	predicted gene 28075	49957	0.13
chr4_20033275_20033475	0.43	Ggh	gamma-glutamyl hydrolase	8677	0.21
chr12_110002868_110003036	0.42	Gm34667	predicted gene, 34667	20921	0.12
chr13_4615952_4616121	0.42	Rpl29-ps2	ribosomal protein L29, pseudogene 2	1854	0.3
chr4_32285860_32286294	0.42	Bach2it1	BTB and CNC homology 2, intronic transcript 1	34316	0.17
chr6_121874198_121874349	0.42	Mug1	murinoglobulin 1	11304	0.19
chr5_61986341_61986512	0.42	Gm42430	predicted gene 42430	17794	0.28
chr10_21665548_21665708	0.41	Gm5420	predicted gene 5420	20783	0.2
chr11_117203569_117203863	0.41	Septin9	septin 9	4055	0.2
chr19_43767883_43768034	0.41	Cutc	cutC copper transporter	3085	0.18
chr2_173108676_173109082	0.41	Ctcflos	CCCTC-binding factor (zinc finger protein)-like, opposite strand	1939	0.29
chr10_83301173_83301511	0.41	Slc41a2	solute carrier family 41, member 2	3033	0.25
chr13_114307307_114307458	0.41	Gm47558	predicted gene, 47558	23001	0.18
chr6_28687920_28688071	0.41	Snd1	staphylococcal nuclease and tudor domain containing 1	16914	0.23
chr4_11861590_11861758	0.41	Gm25002	predicted gene, 25002	87213	0.07
chr6_99175134_99175460	0.41	Foxp1	forkhead box P1	12279	0.28
chr13_59875722_59876043	0.40	Gm48384	predicted gene, 48384	2240	0.23
chr1_93723491_93723642	0.40	Gm10550	predicted gene 10550	7538	0.13
chr4_97028787_97028966	0.40	Gm27521	predicted gene, 27521	111856	0.07
chr4_123005890_123006041	0.40	Mycl	v-myc avian myelocytomatosis viral oncogene lung carcinoma derived	6626	0.15
chr3_82290752_82290920	0.40	Map9	microtubule-associated protein 9	67208	0.12
chr8_94172420_94173095	0.40	Mt2	metallothionein 2	93	0.88
chr9_63109563_63109722	0.40	Gm6082	predicted gene 6082	7559	0.17
chr9_65303383_65303567	0.40	Gm16218	predicted gene 16218	5556	0.11
chr2_45114016_45114230	0.40	Zeb2	zinc finger E-box binding homeobox 2	615	0.66
chr15_38661347_38661720	0.40	Atp6v1c1	ATPase, H+ transporting, lysosomal V1 subunit C1	400	0.79
chr17_70746763_70747075	0.40	5031415H12Rik	RIKEN cDNA 5031415H12 gene	8663	0.19
chr9_116291740_116291898	0.39	D730003K21Rik	RIKEN cDNA D730003K21 gene	35518	0.18
chr6_120242684_120242877	0.39	B4galnt3	beta-1,4-N-acetyl-galactosaminyl transferase 3	137	0.97
chr9_22945594_22945745	0.39	Gm27639	predicted gene, 27639	172834	0.03
chr4_11865116_11865283	0.39	Gm25002	predicted gene, 25002	83688	0.07
chr10_119010946_119011297	0.39	Gm47461	predicted gene, 47461	10549	0.17
chr15_27923668_27923856	0.39	Trio	triple functional domain (PTPRF interacting)	4491	0.26
chr17_34950661_34950834	0.38	Snord52	small nucleolar RNA, C/D box 52	270	0.54
chr12_40027822_40027998	0.38	Arl4a	ADP-ribosylation factor-like 4A	9457	0.19
chr10_85161219_85161370	0.38	Cry1	cryptochrome 1 (photolyase-like)	9938	0.18
chr1_82145347_82145522	0.38	Mir6344	microRNA 6344	13518	0.22
chr9_115401508_115401659	0.38	Gm9487	predicted gene 9487	3566	0.16
chr7_112224273_112224445	0.38	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	1497	0.52
chr11_70713419_70713657	0.38	Mir6925	microRNA 6925	7548	0.08
chr18_34511486_34511736	0.38	n-R5s24	nuclear encoded rRNA 5S 24	1874	0.27
chr18_20668429_20668965	0.38	Ttr	transthyretin	3417	0.2
chr6_51680351_51680512	0.38	Gm38811	predicted gene, 38811	30650	0.19
chr12_55420887_55421038	0.38	Psma6	proteasome subunit alpha 6	13579	0.16
chr11_35179112_35179275	0.38	Slit3	slit guidance ligand 3	1410	0.51
chr12_7987781_7988288	0.38	Apob	apolipoprotein B	10255	0.22
chr6_145335751_145336059	0.38	Gm15707	predicted gene 15707	19297	0.11
chr19_4113049_4113229	0.37	Pitpnm1	phosphatidylinositol transfer protein, membrane-associated 1	819	0.3
chr5_137672268_137672419	0.37	Agfg2	ArfGAP with FG repeats 2	8027	0.08
chr8_51144794_51144945	0.37	Gm45386	predicted gene 45386	7239	0.27
chr16_24090473_24090635	0.37	Gm31583	predicted gene, 31583	465	0.8
chr4_49166497_49166681	0.37	Plppr1	phospholipid phosphatase related 1	107133	0.06
chr2_27420041_27420221	0.37	Vav2	vav 2 oncogene	6781	0.14
chr2_61138777_61138928	0.37	Gm13581	predicted gene 13581	85940	0.09
chr3_96065817_96065981	0.37	Vps45	vacuolar protein sorting 45	7433	0.11
chr9_69331666_69331841	0.37	Gm15511	predicted gene 15511	32494	0.15
chr15_54960594_54960745	0.37	Gm26684	predicted gene, 26684	7721	0.15
chr9_22430143_22430316	0.36	9530077C05Rik	RIKEN cDNA 9530077C05 gene	36	0.96
chr7_84606684_84606960	0.36	Fah	fumarylacetoacetate hydrolase	100	0.96
chr9_48787462_48787613	0.36	Zbtb16	zinc finger and BTB domain containing 16	48408	0.15
chr5_145861209_145861775	0.36	Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	15199	0.15
chr3_19997530_19997681	0.36	Cp	ceruloplasmin	8453	0.18
chr8_90371977_90372137	0.36	Tox3	TOX high mobility group box family member 3	23714	0.27
chr15_31344240_31344565	0.36	Ankrd33b	ankyrin repeat domain 33B	19153	0.14
chr6_35874026_35874908	0.36	Gm43442	predicted gene 43442	52244	0.17
chr10_117301931_117302092	0.36	Lyz1	lysozyme 1	9143	0.14
chr11_84016208_84016387	0.36	Synrg	synergin, gamma	2904	0.26
chr12_82419573_82419742	0.35	Sipa1l1	signal-induced proliferation-associated 1 like 1	958	0.67
chr13_37961453_37961604	0.35	Rreb1	ras responsive element binding protein 1	14512	0.18
chr17_28277643_28277985	0.35	Ppard	peroxisome proliferator activator receptor delta	5695	0.12
chr2_172452446_172453085	0.35	Rtf2	replication termination factor 2	212	0.89
chr13_97341337_97341492	0.35	Gm33447	predicted gene, 33447	34820	0.14
chr2_155539055_155539532	0.35	Mipep-ps	mitochondrial intermediate peptidase, pseudogene	3354	0.11
chr17_56208632_56208824	0.35	Dpp9	dipeptidylpeptidase 9	480	0.64
chr9_43104579_43104740	0.35	Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	827	0.61
chr17_36032663_36032990	0.35	H2-T23	histocompatibility 2, T region locus 23	29	0.92
chr10_119231688_119231864	0.35	Cand1	cullin associated and neddylation disassociated 1	7527	0.21
chr2_4466193_4466360	0.35	Gm13175	predicted gene 13175	394	0.86
chr10_8228115_8228580	0.35	Gm30906	predicted gene, 30906	52216	0.15
chr2_132654710_132655013	0.35	Rpl23a-ps4	ribosomal protein L23A, pseudogene 4	7381	0.12
chr3_60030911_60031238	0.35	Aadac	arylacetamide deacetylase	687	0.65
chr11_83881252_83881469	0.34	Hnf1b	HNF1 homeobox B	28400	0.12
chr10_59442680_59442857	0.34	Oit3	oncoprotein induced transcript 3	990	0.53
chr16_13411734_13411989	0.34	Gm15738	predicted gene 15738	7179	0.17
chr1_191924602_191924813	0.34	1700034H15Rik	RIKEN cDNA 1700034H15 gene	17180	0.13
chr14_41124316_41124467	0.34	Sftpa1	surfactant associated protein A1	7391	0.12
chr14_51102195_51102364	0.34	Rnase4	ribonuclease, RNase A family 4	5920	0.08
chrX_161940825_161941013	0.34	Gm15202	predicted gene 15202	32696	0.21
chr7_3145683_3146014	0.34	Gm29708	predicted gene, 29708	4143	0.09
chr13_45939710_45939875	0.33	4930453C13Rik	RIKEN cDNA 4930453C13 gene	3752	0.25
chr8_41192456_41192607	0.33	Fgl1	fibrinogen-like protein 1	22622	0.16
chr5_8896036_8896187	0.33	Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	2162	0.26
chr13_34074328_34074479	0.33	Tubb2a	tubulin, beta 2A class IIA	3604	0.13
chr4_54615189_54615371	0.33	Gm29067	predicted gene 29067	31000	0.14
chr9_7571293_7571444	0.33	Mmp27	matrix metallopeptidase 27	28	0.97
chr13_98595769_98595925	0.33	Gm4815	predicted gene 4815	17654	0.12
chr3_28736802_28736989	0.33	1700112D23Rik	RIKEN cDNA 1700112D23 gene	5345	0.16
chr9_51994808_51995091	0.33	Gm6981	predicted pseudogene 6981	8332	0.18
chr12_80126678_80126829	0.33	2310015A10Rik	RIKEN cDNA 2310015A10 gene	5614	0.14
chr12_21145146_21145377	0.33	Asap2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	33307	0.16
chr10_61303355_61303525	0.32	Prf1	perforin 1 (pore forming protein)	3639	0.17
chr12_79192021_79192196	0.32	Rdh11	retinol dehydrogenase 11	185	0.9
chr10_25563128_25563279	0.32	Gm29571	predicted gene 29571	26817	0.14
chr16_23319629_23319807	0.32	St6gal1	beta galactoside alpha 2,6 sialyltransferase 1	29248	0.15
chr19_58157498_58157649	0.32	Gm16277	predicted gene 16277	46566	0.16
chr10_78607918_78608069	0.32	Olfr1357	olfactory receptor 1357	4687	0.09
chr4_60070428_60070615	0.32	Mup7	major urinary protein 7	46	0.97
chr7_113219987_113220140	0.32	Arntl	aryl hydrocarbon receptor nuclear translocator-like	12506	0.21
chr3_18069154_18069305	0.32	Gm23726	predicted gene, 23726	97	0.97
chr14_73557741_73557892	0.31	Sucla2	succinate-Coenzyme A ligase, ADP-forming, beta subunit	5050	0.2

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Emx1_Emx2

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	0.6	GO:0009115	xanthine catabolic process(GO:0009115)
0.1	0.3	GO:0061092	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1	0.3	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1	0.3	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.1	0.3	GO:0035513	oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1	0.5	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1	0.4	GO:1990169	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1	0.3	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	0.2	GO:0038161	prolactin signaling pathway(GO:0038161)
0.1	0.2	GO:0061738	late endosomal microautophagy(GO:0061738)
0.1	0.2	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1	0.2	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.1	0.4	GO:0006572	tyrosine catabolic process(GO:0006572)
0.1	0.3	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.1	0.1	GO:0072223	metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.1	0.2	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1	0.2	GO:0015888	thiamine transport(GO:0015888)
0.1	0.3	GO:1903352	ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.1	0.5	GO:2000392	regulation of lamellipodium morphogenesis(GO:2000392)
0.1	0.5	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.1	0.2	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.3	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.1	0.1	GO:0061687	detoxification of inorganic compound(GO:0061687)
0.1	0.1	GO:0070384	Harderian gland development(GO:0070384)
0.1	0.2	GO:0048023	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1	0.4	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.1	0.3	GO:0009642	response to light intensity(GO:0009642)
0.1	0.1	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.1	0.2	GO:0010911	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.1	0.2	GO:1902512	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.1	0.2	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1	0.4	GO:0034374	low-density lipoprotein particle remodeling(GO:0034374)
0.1	0.2	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
0.0	0.1	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.2	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.1	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0	0.1	GO:1900212	mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)
0.0	0.0	GO:1902988	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.0	0.3	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.3	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.1	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282)
0.0	0.1	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.1	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.2	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0	0.3	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.2	GO:1903797	positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0	0.0	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0	0.1	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:0019448	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0	0.1	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.3	GO:0046473	phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0	0.2	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.1	GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0	0.5	GO:0021702	cerebellar Purkinje cell differentiation(GO:0021702)
0.0	0.2	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.2	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.0	0.0	GO:1901145	regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072039) negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072040) mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:1901145) regulation of somatic stem cell population maintenance(GO:1904672) negative regulation of somatic stem cell population maintenance(GO:1904673)
0.0	0.2	GO:0072015	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0	0.2	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0	0.6	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.0	GO:0009155	purine deoxyribonucleotide catabolic process(GO:0009155)
0.0	0.1	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0	0.3	GO:0071888	macrophage apoptotic process(GO:0071888) regulation of macrophage apoptotic process(GO:2000109)
0.0	0.1	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.0	0.1	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.0	0.1	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.0	0.1	GO:0060137	maternal process involved in parturition(GO:0060137)
0.0	0.1	GO:2000850	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0015817	histidine transport(GO:0015817)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.2	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.1	GO:1902093	positive regulation of sperm motility(GO:1902093)
0.0	0.2	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.1	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.1	GO:0051025	negative regulation of immunoglobulin secretion(GO:0051025)
0.0	0.1	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.1	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.1	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.3	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0	0.2	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.2	GO:0072673	lamellipodium morphogenesis(GO:0072673)
0.0	0.1	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0	0.1	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.1	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	0.4	GO:2000810	regulation of bicellular tight junction assembly(GO:2000810)
0.0	0.1	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0	0.1	GO:0071922	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.2	GO:0044351	macropinocytosis(GO:0044351)
0.0	0.2	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.0	GO:0036258	multivesicular body assembly(GO:0036258)
0.0	0.2	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.1	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.1	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.1	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085) negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0	0.1	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.2	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.1	GO:0010825	positive regulation of centrosome duplication(GO:0010825)
0.0	0.1	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.3	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.4	GO:2000811	negative regulation of anoikis(GO:2000811)
0.0	0.1	GO:0010963	regulation of L-arginine import(GO:0010963)
0.0	0.1	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.4	GO:1903392	negative regulation of adherens junction organization(GO:1903392)
0.0	0.1	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	0.2	GO:0002489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.0	0.6	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
0.0	0.1	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	0.3	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.1	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.0	0.1	GO:0051466	positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0	0.2	GO:0051136	regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0090259	regulation of retinal ganglion cell axon guidance(GO:0090259)
0.0	0.3	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.5	GO:0031571	mitotic G1 DNA damage checkpoint(GO:0031571)
0.0	0.1	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.1	GO:0060336	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.1	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.1	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.2	GO:0051189	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.1	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.0	0.1	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.1	GO:1903116	positive regulation of actin filament-based movement(GO:1903116)
0.0	0.1	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.0	0.2	GO:0042436	tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0	0.1	GO:0031049	programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052)
0.0	0.2	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210)
0.0	0.1	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0	0.1	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.1	GO:0006534	cysteine metabolic process(GO:0006534)
0.0	0.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:0072674	multinuclear osteoclast differentiation(GO:0072674)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.0	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0	0.3	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.4	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
0.0	0.2	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.0	GO:0034372	very-low-density lipoprotein particle remodeling(GO:0034372)
0.0	0.0	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.0	0.1	GO:0051410	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0	0.0	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0	0.1	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.0	0.1	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.0	0.1	GO:2000468	regulation of peroxidase activity(GO:2000468)
0.0	0.1	GO:0032348	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0	0.1	GO:0070673	response to interleukin-18(GO:0070673)
0.0	0.1	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.0	0.1	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.1	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.0	GO:0032513	regulation of protein phosphatase type 2B activity(GO:0032512) negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.0	0.0	GO:0032429	regulation of phospholipase A2 activity(GO:0032429)
0.0	0.1	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.1	GO:0014745	negative regulation of muscle adaptation(GO:0014745)
0.0	0.0	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.0	0.1	GO:0070889	platelet alpha granule organization(GO:0070889)
0.0	0.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.1	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.0	0.0	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)
0.0	0.1	GO:0061727	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.1	GO:0051660	establishment of centrosome localization(GO:0051660)
0.0	0.1	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.0	GO:0002309	T cell proliferation involved in immune response(GO:0002309)
0.0	0.1	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.0	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.0	0.1	GO:0042761	very long-chain fatty acid biosynthetic process(GO:0042761)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.2	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.0	GO:0009080	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.1	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.1	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0	0.1	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.1	GO:0034239	regulation of macrophage fusion(GO:0034239)
0.0	0.0	GO:0009946	proximal/distal axis specification(GO:0009946)
0.0	0.0	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.0	0.1	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.1	GO:0046125	pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0	1.1	GO:0007566	embryo implantation(GO:0007566)
0.0	0.0	GO:2000481	positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0002540	leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.1	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.0	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.0	GO:0034182	regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
0.0	0.2	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0	0.1	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0	0.0	GO:0021648	vestibulocochlear nerve morphogenesis(GO:0021648)
0.0	0.1	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.0	0.1	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.0	0.1	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.1	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0070836	caveola assembly(GO:0070836)
0.0	0.0	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.4	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.0	0.1	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.1	GO:0032596	protein transport into membrane raft(GO:0032596)
0.0	0.1	GO:0071316	cellular response to nicotine(GO:0071316)
0.0	0.0	GO:0032776	DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776)
0.0	0.4	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.1	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.0	0.0	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0	0.2	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.0	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0	0.1	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.0	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.0	GO:0060018	astrocyte fate commitment(GO:0060018)
0.0	0.2	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.0	0.1	GO:1904995	negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0	0.1	GO:0032906	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0	0.0	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.0	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.0	0.1	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.1	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.1	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.1	GO:0052428	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0	0.1	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.1	GO:0003344	pericardium morphogenesis(GO:0003344)
0.0	0.0	GO:0030497	fatty acid elongation(GO:0030497)
0.0	0.0	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.0	0.1	GO:0016078	tRNA catabolic process(GO:0016078)
0.0	0.0	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0	0.0	GO:0031296	B cell costimulation(GO:0031296)
0.0	0.0	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.0	0.1	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.0	GO:0045448	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0	0.0	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0	0.0	GO:0070460	thyroid-stimulating hormone secretion(GO:0070460)
0.0	0.2	GO:0006825	copper ion transport(GO:0006825)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	0.0	GO:0032875	regulation of DNA endoreduplication(GO:0032875)
0.0	0.0	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.0	0.0	GO:1902730	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0	0.1	GO:0036010	protein localization to endosome(GO:0036010)
0.0	0.1	GO:0051799	negative regulation of hair follicle development(GO:0051799)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.1	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.1	GO:0000097	sulfur amino acid biosynthetic process(GO:0000097)
0.0	0.0	GO:0008228	opsonization(GO:0008228)
0.0	0.0	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.0	0.4	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0	0.0	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.0	0.1	GO:0097062	dendritic spine maintenance(GO:0097062)
0.0	0.0	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0	0.2	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:0044154	histone H3-K14 acetylation(GO:0044154)
0.0	0.0	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0	0.0	GO:0070431	nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0	0.0	GO:0007403	glial cell fate determination(GO:0007403)
0.0	0.0	GO:0010025	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0	0.2	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.0	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.0	GO:0035262	gonad morphogenesis(GO:0035262)
0.0	0.0	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0048069	eye pigmentation(GO:0048069)
0.0	0.0	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.0	GO:0030300	regulation of intestinal cholesterol absorption(GO:0030300)
0.0	0.4	GO:0061001	regulation of dendritic spine morphogenesis(GO:0061001)
0.0	0.0	GO:2000836	androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.0	0.0	GO:0040031	snRNA modification(GO:0040031)
0.0	0.0	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.0	0.0	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.0	GO:0002432	granuloma formation(GO:0002432)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.1	GO:0050915	sensory perception of sour taste(GO:0050915)
0.0	0.1	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0	0.1	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.0	0.1	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.0	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.0	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.0	GO:1903660	complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.0	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.2	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.2	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.0	GO:0051661	maintenance of centrosome location(GO:0051661)
0.0	0.0	GO:0080009	mRNA methylation(GO:0080009)
0.0	0.0	GO:0035928	rRNA import into mitochondrion(GO:0035928)
0.0	0.1	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0	0.1	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0	0.1	GO:0097527	necroptotic signaling pathway(GO:0097527)
0.0	0.1	GO:0010991	regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.0	GO:0009838	abscission(GO:0009838)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.0	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.1	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.0	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242)
0.0	0.1	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
0.0	0.0	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0	0.0	GO:0021943	formation of radial glial scaffolds(GO:0021943)
0.0	0.1	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.0	GO:0015744	succinate transport(GO:0015744)
0.0	0.0	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.0	GO:0035630	bone mineralization involved in bone maturation(GO:0035630)
0.0	0.0	GO:0048320	axial mesoderm formation(GO:0048320)
0.0	0.0	GO:0001765	membrane raft assembly(GO:0001765)
0.0	0.4	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.0	GO:2000630	positive regulation of miRNA metabolic process(GO:2000630)
0.0	0.0	GO:0035962	response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.0	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0	0.0	GO:0018992	germ-line sex determination(GO:0018992)
0.0	0.0	GO:1904668	positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.0	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0	0.0	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.0	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.1	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.0	0.0	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.1	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.1	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.0	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.0	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.0	GO:0021524	visceral motor neuron differentiation(GO:0021524)
0.0	0.0	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0	0.0	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0	0.1	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.0	0.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.0	GO:0001865	NK T cell differentiation(GO:0001865)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.0	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0	0.0	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.0	0.0	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.0	0.0	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.0	0.0	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.0	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.0	0.1	GO:0051601	exocyst localization(GO:0051601)
0.0	0.1	GO:0051798	regulation of hair follicle development(GO:0051797) positive regulation of hair follicle development(GO:0051798)
0.0	0.1	GO:0090232	positive regulation of spindle checkpoint(GO:0090232)
0.0	0.1	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.1	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.2	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.0	GO:0006083	acetate metabolic process(GO:0006083)
0.0	0.0	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0	0.0	GO:0043504	mitochondrial DNA repair(GO:0043504)
0.0	0.1	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
0.0	0.0	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.0	0.1	GO:0015919	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0	0.0	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.1	GO:1902473	regulation of protein localization to synapse(GO:1902473)
0.0	0.0	GO:0002892	type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type IIa hypersensitivity(GO:0001798) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) positive regulation of type II hypersensitivity(GO:0002894)
0.0	0.2	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.0	GO:0035927	RNA import into mitochondrion(GO:0035927)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.0	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0	0.0	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.0	0.0	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.0	0.1	GO:0060330	regulation of response to interferon-gamma(GO:0060330)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.1	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	0.3	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.1	0.3	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1	0.3	GO:0005638	lamin filament(GO:0005638)
0.1	0.2	GO:1990246	uniplex complex(GO:1990246)
0.1	0.2	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.2	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.1	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.3	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.2	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.4	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.3	GO:0031209	SCAR complex(GO:0031209)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.5	GO:0000974	Prp19 complex(GO:0000974)
0.0	0.1	GO:0009279	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.3	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.4	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.2	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.3	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.1	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.1	GO:0033503	HULC complex(GO:0033503)
0.0	0.1	GO:0000235	astral microtubule(GO:0000235)
0.0	0.1	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.0	0.4	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.0	0.2	GO:0090543	Flemming body(GO:0090543)
0.0	0.4	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.2	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.2	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.3	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.1	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.3	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0035838	growing cell tip(GO:0035838)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.3	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0	0.1	GO:0051286	cell tip(GO:0051286)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.1	GO:0000798	nuclear cohesin complex(GO:0000798)
0.0	0.1	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.2	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.2	GO:0032797	SMN complex(GO:0032797)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.1	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.1	GO:0042627	chylomicron(GO:0042627)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.0	GO:0070820	tertiary granule(GO:0070820)
0.0	0.0	GO:0097513	myosin II filament(GO:0097513)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.0	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.1	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.0	GO:1990761	growth cone lamellipodium(GO:1990761)
0.0	0.1	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.2	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.0	GO:0036396	MIS complex(GO:0036396)
0.0	0.1	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.2	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.1	GO:0033391	chromatoid body(GO:0033391)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.0	GO:0045251	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0	0.0	GO:0033010	paranodal junction(GO:0033010)
0.0	0.0	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.0	GO:0005818	aster(GO:0005818)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.0	GO:0035363	histone locus body(GO:0035363)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.0	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.0	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.0	GO:0030891	VCB complex(GO:0030891)
0.0	0.0	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.0	0.0	GO:0097512	cardiac myofibril(GO:0097512)
0.0	0.0	GO:0032127	dense core granule membrane(GO:0032127)
0.0	0.1	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.1	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.0	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.0	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.0	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.2	GO:0031985	Golgi cisterna(GO:0031985)
0.0	0.1	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1	0.1	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.1	0.6	GO:0030151	molybdenum ion binding(GO:0030151)
0.1	0.4	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.3	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.1	0.3	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.1	0.3	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.3	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.6	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.5	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.1	0.2	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.1	0.4	GO:0004630	phospholipase D activity(GO:0004630)
0.1	0.2	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1	0.4	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.1	0.3	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.1	0.4	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.2	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.2	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.3	GO:0034819	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.0	0.1	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.0	0.5	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.2	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.6	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.3	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.2	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.2	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.2	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.3	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.0	0.1	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.1	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.4	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.3	GO:0070513	death domain binding(GO:0070513)
0.0	0.2	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0004772	sterol O-acyltransferase activity(GO:0004772)
0.0	0.2	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.0	GO:0018636	phenanthrene 9,10-monooxygenase activity(GO:0018636)
0.0	0.1	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.0	0.1	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.0	0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.1	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.3	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.2	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.0	GO:0030523	S-acetyltransferase activity(GO:0016418) dihydrolipoamide S-acyltransferase activity(GO:0030523)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0102344	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0	0.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.1	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.1	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.2	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.1	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.2	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.1	GO:0030984	kininogen binding(GO:0030984)
0.0	0.1	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.1	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.3	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.3	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.1	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.0	GO:0016726	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0	0.3	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.1	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.1	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.2	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.2	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0019862	IgA binding(GO:0019862)
0.0	0.0	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.0	0.1	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.0	0.4	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.2	GO:0016594	glycine binding(GO:0016594)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.1	GO:0018585	fluorene oxygenase activity(GO:0018585)
0.0	0.1	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.0	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.0	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0	0.1	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.0	0.0	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0	0.2	GO:0019841	retinol binding(GO:0019841)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.3	GO:0019825	oxygen binding(GO:0019825)
0.0	0.0	GO:0071209	U7 snRNA binding(GO:0071209)
0.0	0.0	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.0	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.0	0.1	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.2	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.5	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0016453	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.0	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.0	0.0	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.4	GO:0016414	O-octanoyltransferase activity(GO:0016414)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.4	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.0	GO:0030519	snoRNP binding(GO:0030519)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.0	GO:0061513	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.2	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.0	GO:0019002	GMP binding(GO:0019002)
0.0	0.0	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.2	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.1	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
0.0	0.5	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.1	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0	0.0	GO:0031781	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.0	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0	0.2	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0043912	D-lysine oxidase activity(GO:0043912)
0.0	0.0	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.0	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0	0.0	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.0	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0	0.0	GO:0045340	mercury ion binding(GO:0045340)
0.0	0.0	GO:0016751	S-succinyltransferase activity(GO:0016751)
0.0	0.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.0	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.0	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.0	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.0	GO:0043199	sulfate binding(GO:0043199)
0.0	0.0	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.0	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.0	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.1	GO:0005542	folic acid binding(GO:0005542)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.0	GO:0031686	A1 adenosine receptor binding(GO:0031686)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.0	GO:0008410	CoA-transferase activity(GO:0008410)
0.0	0.3	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.4	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.1	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
0.0	0.1	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.7	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.0	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.0	GO:0018812	3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
0.0	0.0	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.0	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0015266	protein channel activity(GO:0015266)
0.0	0.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.0	GO:0005148	prolactin receptor binding(GO:0005148)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	0.4	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	1.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.7	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.2	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.2	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.1	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.6	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.3	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.0	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.6	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.1	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.2	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.0	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.6	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.3	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.0	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.2	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.5	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.3	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.1	PID GMCSF PATHWAY	GMCSF-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.1	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.6	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.2	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.0	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.4	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.0	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.3	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.4	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.0	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.1	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.6	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.8	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.0	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.0	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.0	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.0	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME MEIOSIS	Genes involved in Meiosis
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis

Results for Emx1_Emx2

Z-value: 2.08

Motif logo

Transcription factors associated with Emx1_Emx2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Emx1_Emx2 motif across conditions

Conditions sorted by the z-value of the Emx1_Emx2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Emx1_Emx2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: