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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for En2

Z-value: 0.79

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Transcription factors associated with En2

Gene Symbol	Gene ID	Gene Info
En2 Ensembl NCBI MGI UniProt	ENSMUSG00000039095.7	En2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
En2	chr5_28123154_28123318	42458	0.112114	0.75	8.9e-02	Click!

Activity of the En2 motif across conditions

Conditions sorted by the z-value of the En2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr19_44400352_44400581	0.66	Scd1	stearoyl-Coenzyme A desaturase 1	6224	0.15
chr16_93333790_93334136	0.57	1810053B23Rik	RIKEN cDNA 1810053B23 gene	19226	0.18
chr17_81386211_81386362	0.53	Gm50044	predicted gene, 50044	15453	0.24
chr19_44402814_44402965	0.51	Scd1	stearoyl-Coenzyme A desaturase 1	3801	0.18
chr14_51289465_51289616	0.44	Gm49245	predicted gene, 49245	11938	0.1
chr12_30922518_30922679	0.41	Sh3yl1	Sh3 domain YSC-like 1	10411	0.17
chr6_58611375_58611579	0.40	Abcg2	ATP binding cassette subfamily G member 2 (Junior blood group)	14806	0.19
chr9_106788095_106788832	0.40	Rad54l2	RAD54 like 2 (S. cerevisiae)	713	0.62
chr9_41328613_41328764	0.40	Mir100hg	Mir100 Mirlet7a-2 Mir125b-1 cluster host gene	78	0.97
chr3_119368468_119368634	0.36	Gm23432	predicted gene, 23432	270323	0.02
chr13_117745874_117746186	0.36	4933413L06Rik	RIKEN cDNA 4933413L06 gene	26019	0.26
chr16_97905608_97905790	0.36	C2cd2	C2 calcium-dependent domain containing 2	13418	0.17
chr8_108703572_108703757	0.34	Zfhx3	zinc finger homeobox 3	564	0.82
chr19_44401346_44401497	0.34	Scd1	stearoyl-Coenzyme A desaturase 1	5269	0.16
chr10_51233946_51234117	0.34	Gm5040	predicted gene 5040	4798	0.28
chr6_119404440_119404707	0.33	Adipor2	adiponectin receptor 2	12902	0.2
chr12_73861884_73862127	0.32	Gm15283	predicted gene 15283	7607	0.18
chr2_18048778_18049088	0.30	Skida1	SKI/DACH domain containing 1	98	0.94
chr14_21435070_21435221	0.30	Gm25864	predicted gene, 25864	15329	0.19
chr1_151154930_151155204	0.30	C730036E19Rik	RIKEN cDNA C730036E19 gene	17033	0.11
chr7_64513340_64513540	0.29	Gm45082	predicted gene 45082	1871	0.32
chr1_74740134_74740308	0.29	Cyp27a1	cytochrome P450, family 27, subfamily a, polypeptide 1	3412	0.15
chr9_115401508_115401659	0.29	Gm9487	predicted gene 9487	3566	0.16
chr7_49523973_49524159	0.28	Nav2	neuron navigator 2	24126	0.22
chr9_22430143_22430316	0.28	9530077C05Rik	RIKEN cDNA 9530077C05 gene	36	0.96
chr5_125526040_125526191	0.27	Tmem132b	transmembrane protein 132B	5659	0.17
chr10_67107041_67107217	0.26	Reep3	receptor accessory protein 3	10184	0.2
chr4_71609659_71609810	0.26	Gm11231	predicted gene 11231	68279	0.13
chr6_142345778_142346191	0.25	Pyroxd1	pyridine nucleotide-disulphide oxidoreductase domain 1	306	0.86
chr12_71296545_71296978	0.25	Dact1	dishevelled-binding antagonist of beta-catenin 1	13123	0.14
chr9_70942553_70942713	0.25	Lipc	lipase, hepatic	7825	0.21
chr11_119970402_119970571	0.24	Baiap2	brain-specific angiogenesis inhibitor 1-associated protein 2	10465	0.11
chr7_30967090_30967447	0.24	Lsr	lipolysis stimulated lipoprotein receptor	6054	0.07
chr1_92730752_92730936	0.24	Gm29483	predicted gene 29483	13642	0.14
chr6_72155996_72156358	0.24	Gm38832	predicted gene, 38832	6672	0.15
chr16_58629623_58629774	0.24	Ftdc2	ferritin domain containing 2	9041	0.14
chr4_148143306_148143457	0.24	Mad2l2	MAD2 mitotic arrest deficient-like 2	1409	0.24
chr13_35463284_35463451	0.24	Gm48703	predicted gene, 48703	67984	0.1
chr19_3840572_3840723	0.24	Chka	choline kinase alpha	11126	0.09
chr5_138080510_138080792	0.24	Zkscan1	zinc finger with KRAB and SCAN domains 1	4433	0.1
chr4_53104702_53105001	0.23	Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	55044	0.11
chr11_21713674_21713848	0.23	Wdpcp	WD repeat containing planar cell polarity effector	18632	0.2
chr4_26470101_26470279	0.23	Gm11903	predicted gene 11903	27729	0.19
chr8_46492911_46493695	0.23	Acsl1	acyl-CoA synthetase long-chain family member 1	471	0.78
chr19_47313793_47313952	0.23	Sh3pxd2a	SH3 and PX domains 2A	879	0.58
chr13_115653330_115653690	0.23	Gm47892	predicted gene, 47892	65989	0.13
chrX_140538466_140538617	0.23	Tsc22d3	TSC22 domain family, member 3	4127	0.24
chr18_44633864_44634028	0.22	A930012L18Rik	RIKEN cDNA A930012L18 gene	27719	0.19
chr10_59786230_59786381	0.22	Gm17059	predicted gene 17059	13949	0.14
chr6_58611617_58611884	0.22	Abcg2	ATP binding cassette subfamily G member 2 (Junior blood group)	15079	0.19
chr8_122697244_122697412	0.22	Gm10612	predicted gene 10612	532	0.59
chr1_61639417_61639568	0.22	Pard3b	par-3 family cell polarity regulator beta	249	0.9
chr2_67977965_67978321	0.22	Gm37964	predicted gene, 37964	79547	0.1
chr3_130709873_130710026	0.22	Ostc	oligosaccharyltransferase complex subunit (non-catalytic)	505	0.69
chr1_13368915_13369352	0.22	Ncoa2	nuclear receptor coactivator 2	3296	0.16
chr14_68299957_68300145	0.22	Gm47212	predicted gene, 47212	81798	0.09
chr8_67944016_67944202	0.22	Psd3	pleckstrin and Sec7 domain containing 3	7770	0.23
chr5_122936823_122936974	0.21	Kdm2b	lysine (K)-specific demethylase 2B	11096	0.13
chr9_102975773_102975938	0.21	Slco2a1	solute carrier organic anion transporter family, member 2a1	12857	0.17
chr16_78574210_78574428	0.21	D16Ertd472e	DNA segment, Chr 16, ERATO Doi 472, expressed	2315	0.29
chr1_132800530_132800731	0.21	Gm22609	predicted gene, 22609	13718	0.19
chr13_50595486_50595664	0.21	Mir683-2	microRNA 683-2	5505	0.18
chr2_103600204_103600386	0.21	Abtb2	ankyrin repeat and BTB (POZ) domain containing 2	33985	0.15
chr10_23837916_23838078	0.21	Vnn3	vanin 3	13465	0.12
chr18_60606060_60606525	0.21	Synpo	synaptopodin	3813	0.19
chr2_77155937_77156088	0.21	Ccdc141	coiled-coil domain containing 141	14564	0.21
chr19_42118053_42118204	0.21	Pi4k2a	phosphatidylinositol 4-kinase type 2 alpha	3450	0.14
chr6_33823830_33824315	0.20	Exoc4	exocyst complex component 4	38028	0.2
chr9_112027249_112027400	0.20	Mir128-2	microRNA 128-2	91387	0.08
chr18_32560196_32560347	0.20	Gypc	glycophorin C	237	0.94
chr14_28505648_28505933	0.20	Wnt5a	wingless-type MMTV integration site family, member 5A	110	0.97
chr9_23436438_23436789	0.20	Bmper	BMP-binding endothelial regulator	62681	0.16
chr4_144913207_144913382	0.20	Dhrs3	dehydrogenase/reductase (SDR family) member 3	5585	0.23
chr5_33269323_33269474	0.20	Ctbp1	C-terminal binding protein 1	90	0.96
chr5_89452029_89452180	0.20	Gc	vitamin D binding protein	5794	0.25
chr5_44241551_44241719	0.20	Tapt1	transmembrane anterior posterior transformation 1	15009	0.11
chr6_29828721_29828890	0.20	Ahcyl2	S-adenosylhomocysteine hydrolase-like 2	24955	0.16
chr4_120076409_120076580	0.20	AL607142.1	novel protein	11498	0.22
chr4_115597563_115597714	0.19	Cyp4a32	cytochrome P450, family 4, subfamily a, polypeptide 32	3331	0.16
chr16_38246128_38246487	0.19	Gsk3b	glycogen synthase kinase 3 beta	38269	0.11
chr15_36578902_36579081	0.19	Gm44310	predicted gene, 44310	4553	0.16
chr9_43808674_43808844	0.19	Nectin1	nectin cell adhesion molecule 1	12188	0.18
chr10_21464742_21464927	0.19	Gm48386	predicted gene, 48386	19198	0.15
chr13_37756552_37756712	0.19	Gm31600	predicted gene, 31600	5116	0.16
chr4_49340688_49340844	0.19	Gm12453	predicted gene 12453	1482	0.35
chr5_140794441_140794653	0.19	Gna12	guanine nucleotide binding protein, alpha 12	35610	0.14
chr14_8302836_8303294	0.19	Fam107a	family with sequence similarity 107, member A	6712	0.2
chr4_52516557_52516729	0.19	Vma21-ps	VMA21 vacuolar H+-ATPase homolog (S. cerevisiae), pseudogene	19399	0.2
chr13_90923293_90923612	0.19	Rps23	ribosomal protein S23	235	0.94
chr5_121431395_121431558	0.19	Naa25	N(alpha)-acetyltransferase 25, NatB auxiliary subunit	7942	0.1
chr14_60387250_60387782	0.19	Amer2	APC membrane recruitment 2	9230	0.22
chr11_79792604_79792780	0.19	9130204K15Rik	RIKEN cDNA 9130204K15 gene	9805	0.18
chr9_43823795_43823946	0.19	Nectin1	nectin cell adhesion molecule 1	2923	0.26
chr3_35169015_35169202	0.19	1700017M07Rik	RIKEN cDNA 1700017M07 gene	107023	0.07
chr10_42271611_42271917	0.19	Foxo3	forkhead box O3	4932	0.28
chr9_48675501_48675665	0.19	Nnmt	nicotinamide N-methyltransferase	70430	0.11
chr10_99600138_99600289	0.18	Gm20110	predicted gene, 20110	8958	0.19
chr17_6966018_6966169	0.18	Rnaset2b	ribonuclease T2B	4541	0.13
chr11_30792834_30792985	0.18	Psme4	proteasome (prosome, macropain) activator subunit 4	18628	0.14
chr3_58685911_58686282	0.18	Siah2	siah E3 ubiquitin protein ligase 2	59	0.96
chr9_60982764_60983106	0.18	Gm5122	predicted gene 5122	30546	0.14
chr8_35495669_35495888	0.18	Eri1	exoribonuclease 1	245	0.93
chr3_145992046_145992317	0.18	Syde2	synapse defective 1, Rho GTPase, homolog 2 (C. elegans)	1490	0.39
chr7_39487472_39487798	0.18	Gm28455	predicted gene 28455	1803	0.25
chr8_45719244_45719451	0.18	Sorbs2	sorbin and SH3 domain containing 2	23834	0.18
chr7_144551116_144551314	0.18	Ppfia1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	1147	0.45
chr9_108296266_108296431	0.18	Amt	aminomethyltransferase	505	0.57
chr11_62409500_62409860	0.18	Ncor1	nuclear receptor co-repressor 1	8130	0.16
chr15_89377019_89377232	0.18	Tymp	thymidine phosphorylase	86	0.89
chr5_45473392_45473560	0.18	Clrn2	clarin 2	19725	0.11
chr5_52975538_52975768	0.18	Gm30301	predicted gene, 30301	6384	0.16
chr16_77467204_77467401	0.18	Gm37063	predicted gene, 37063	9632	0.12
chr14_25916848_25916999	0.18	Tmem254a	transmembrane protein 254a	8865	0.12
chr19_30093178_30093359	0.18	Uhrf2	ubiquitin-like, containing PHD and RING finger domains 2	1307	0.48
chr7_123850711_123850906	0.17	Gm23788	predicted gene, 23788	91401	0.08
chr18_76242274_76242708	0.17	Smad2	SMAD family member 2	317	0.89
chr12_79436149_79436313	0.17	Rad51b	RAD51 paralog B	108878	0.06
chr16_76319982_76320335	0.17	Nrip1	nuclear receptor interacting protein 1	3500	0.3
chr3_51255928_51256079	0.17	Elf2	E74-like factor 2	4238	0.15
chr10_68327935_68328096	0.17	4930545H06Rik	RIKEN cDNA 4930545H06 gene	6873	0.22
chr8_35216178_35216374	0.17	Gm34474	predicted gene, 34474	2362	0.23
chr15_78839984_78840135	0.17	Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	2565	0.14
chr7_64802263_64802423	0.17	Fam189a1	family with sequence similarity 189, member A1	28691	0.19
chr10_61666021_61666218	0.17	Ppa1	pyrophosphatase (inorganic) 1	2430	0.19
chr9_70237659_70237810	0.17	Myo1e	myosin IE	30366	0.18
chr17_70848513_70848664	0.17	Tgif1	TGFB-induced factor homeobox 1	1056	0.34
chr14_26056611_26056762	0.17	Tmem254c	transmembrane protein 254c	8855	0.11
chr3_27938338_27938489	0.17	Pld1	phospholipase D1	282	0.93
chr10_69268049_69268226	0.17	Rhobtb1	Rho-related BTB domain containing 1	2500	0.29
chr11_115244535_115244760	0.17	Gm25837	predicted gene, 25837	8631	0.11
chr18_20969991_20970173	0.16	Rnf125	ring finger protein 125	8610	0.21
chr14_70566111_70566293	0.16	Hr	lysine demethylase and nuclear receptor corepressor	10302	0.1
chr17_3114053_3114243	0.16	Gm21926	predicted gene, 21926	602	0.43
chr17_49304784_49304935	0.16	Gm17830	predicted gene, 17830	7382	0.19
chr14_70530138_70530323	0.16	Lgi3	leucine-rich repeat LGI family, member 3	455	0.68
chr6_57523099_57523250	0.16	Ppm1k	protein phosphatase 1K (PP2C domain containing)	7567	0.15
chr8_109795573_109795879	0.16	Ap1g1	adaptor protein complex AP-1, gamma 1 subunit	16820	0.14
chr4_101198122_101198415	0.16	Gm24468	predicted gene, 24468	11504	0.14
chr16_13411734_13411989	0.16	Gm15738	predicted gene 15738	7179	0.17
chr9_46036951_46037323	0.16	Sik3	SIK family kinase 3	24137	0.13
chr7_128057750_128057908	0.16	Gm22809	predicted gene, 22809	4031	0.09
chr10_93490488_93490639	0.16	Hal	histidine ammonia lyase	1760	0.28
chr2_31505484_31505674	0.16	Ass1	argininosuccinate synthetase 1	4853	0.2
chr8_3277082_3277233	0.16	Insr	insulin receptor	2394	0.29
chr6_108135683_108135868	0.16	Rpl36-ps12	ribosomal protein L36, pseudogene 12	4734	0.23
chr9_43825824_43825990	0.16	Nectin1	nectin cell adhesion molecule 1	3924	0.23
chr14_45588309_45588536	0.16	Gm15601	predicted gene 15601	682	0.52
chr12_80181689_80181850	0.16	Actn1	actinin, alpha 1	3079	0.19
chr6_140187703_140187872	0.16	Gm24174	predicted gene, 24174	21142	0.18
chr9_122056710_122056883	0.16	Gm39465	predicted gene, 39465	5333	0.13
chr3_14854527_14854724	0.16	Car3	carbonic anhydrase 3	8887	0.18
chr8_109998140_109998715	0.16	Tat	tyrosine aminotransferase	7921	0.12
chr10_42230294_42230483	0.16	Foxo3	forkhead box O3	27978	0.22
chr19_40463615_40463981	0.16	Sorbs1	sorbin and SH3 domain containing 1	12408	0.21
chr14_101841763_101841965	0.16	Lmo7	LIM domain only 7	1045	0.64
chr8_90831859_90832023	0.16	Chd9	chromodomain helicase DNA binding protein 9	3085	0.18
chr6_90499813_90499975	0.16	Gm44236	predicted gene, 44236	13408	0.1
chr8_120351500_120351658	0.16	Gm22715	predicted gene, 22715	91970	0.06
chr6_29841360_29841511	0.15	Ahcyl2	S-adenosylhomocysteine hydrolase-like 2	12325	0.18
chr8_109996628_109997116	0.15	Tat	tyrosine aminotransferase	6366	0.13
chr7_19684170_19684408	0.15	Apoc4	apolipoprotein C-IV	2810	0.1
chr6_6213107_6213286	0.15	Slc25a13	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13	3922	0.28
chr15_59823011_59823164	0.15	Gm19510	predicted gene, 19510	28128	0.21
chr7_112187893_112188109	0.15	Dkk3	dickkopf WNT signaling pathway inhibitor 3	28944	0.2
chr15_102999275_102999447	0.15	Hoxc6	homeobox C6	1104	0.28
chr11_120523107_120523310	0.15	Gm11789	predicted gene 11789	7346	0.07
chr4_15212980_15213172	0.15	Tmem64	transmembrane protein 64	52755	0.13
chr11_67535494_67535665	0.15	Gas7	growth arrest specific 7	11575	0.23
chr4_11609051_11609282	0.15	Rad54b	RAD54 homolog B (S. cerevisiae)	209	0.92
chr9_114763477_114763635	0.15	Cmtm7	CKLF-like MARVEL transmembrane domain containing 7	11895	0.15
chr11_4098038_4098510	0.15	Mtfp1	mitochondrial fission process 1	2829	0.13
chr15_76574596_76574756	0.15	Adck5	aarF domain containing kinase 5	1682	0.15
chr11_88618769_88618942	0.15	Msi2	musashi RNA-binding protein 2	28708	0.2
chr13_112473176_112473327	0.15	Il6st	interleukin 6 signal transducer	652	0.68
chr15_3463467_3463618	0.15	Ghr	growth hormone receptor	8102	0.29
chr17_10235141_10235292	0.15	Qk	quaking	21642	0.25
chr3_142375387_142375618	0.15	Pdlim5	PDZ and LIM domain 5	16306	0.24
chr3_95881097_95881422	0.15	Ciart	circadian associated repressor of transcription	13	0.94
chr15_80683897_80684048	0.15	Fam83f	family with sequence similarity 83, member F	12125	0.12
chr11_35750589_35750898	0.15	Pank3	pantothenate kinase 3	18741	0.16
chr6_71909397_71909610	0.15	Polr1a	polymerase (RNA) I polypeptide A	434	0.58
chr13_24981001_24981315	0.15	Mrs2	MRS2 magnesium transporter	13641	0.14
chr11_18900228_18900379	0.15	2900018N21Rik	RIKEN cDNA 2900018N21 gene	10463	0.16
chr17_31065905_31066059	0.15	Gm25447	predicted gene, 25447	6378	0.14
chr8_108895943_108896094	0.15	Gm20686	predicted gene 20686	25856	0.18
chr3_55112219_55112827	0.15	Spg20	spastic paraplegia 20, spartin (Troyer syndrome) homolog (human)	73	0.97
chr7_118544510_118544696	0.15	Coq7	demethyl-Q 7	11247	0.14
chr19_23309882_23310048	0.14	Gm24263	predicted gene, 24263	13636	0.18
chr3_157729822_157729986	0.14	Gm33466	predicted gene, 33466	3496	0.3
chr5_22549698_22549942	0.14	Orc5	origin recognition complex, subunit 5	302	0.68
chr5_102728907_102729240	0.14	Arhgap24	Rho GTPase activating protein 24	4100	0.36
chr8_116539027_116539192	0.14	Dynlrb2	dynein light chain roadblock-type 2	34094	0.19
chr7_143068403_143068570	0.14	Tssc4	tumor-suppressing subchromosomal transferable fragment 4	763	0.46
chr6_52610697_52610915	0.14	Gm44434	predicted gene, 44434	7561	0.15
chr10_44697885_44698061	0.14	Gm47388	predicted gene, 47388	793	0.5
chr8_41096427_41096618	0.14	Mtus1	mitochondrial tumor suppressor 1	13746	0.18
chr7_126975670_126975892	0.14	Cdiptos	CDIP transferase, opposite strand	7	0.61
chr19_9049073_9049224	0.14	Scgb1a1	secretoglobin, family 1A, member 1 (uteroglobin)	38810	0.09
chr9_48860359_48860556	0.14	Zbtb16	zinc finger and BTB domain containing 16	24235	0.17
chrX_103286700_103286914	0.14	4930519F16Rik	RIKEN cDNA 4930519F16 gene	1271	0.27

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of En2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:1903964	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1	0.3	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.1	0.2	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1	0.2	GO:0048696	regulation of collateral sprouting in absence of injury(GO:0048696)
0.1	0.2	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.0	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.1	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.1	GO:0071727	response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0	0.2	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.2	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.2	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.1	GO:0035973	aggrephagy(GO:0035973)
0.0	0.3	GO:0046473	phosphatidic acid metabolic process(GO:0046473)
0.0	0.1	GO:0009093	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0	0.1	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.0	0.1	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.1	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0061152	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0	0.1	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.2	GO:0090241	negative regulation of histone H4 acetylation(GO:0090241)
0.0	0.1	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.1	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0	0.1	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.1	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.0	0.1	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.0	0.2	GO:0000467	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0	0.1	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.0	0.1	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0	0.1	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.0	0.1	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
0.0	0.1	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.0	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.0	GO:2000040	regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.1	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0	0.1	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.0	GO:0061010	gall bladder development(GO:0061010)
0.0	0.1	GO:0051799	negative regulation of hair follicle development(GO:0051799)
0.0	0.1	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0003383	apical constriction(GO:0003383)
0.0	0.1	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.1	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.1	GO:0052205	modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205)
0.0	0.0	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.0	0.0	GO:0009155	purine deoxyribonucleotide catabolic process(GO:0009155)
0.0	0.1	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.0	GO:0010963	regulation of L-arginine import(GO:0010963)
0.0	0.0	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.1	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.0	0.0	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.0	GO:1904179	positive regulation of adipose tissue development(GO:1904179)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.0	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.1	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.1	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0	0.0	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:1905049	negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0	0.1	GO:0070458	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0	0.1	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.1	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.0	GO:0046098	guanine metabolic process(GO:0046098)
0.0	0.1	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0	0.1	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.0	0.0	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.0	0.2	GO:0045475	locomotor rhythm(GO:0045475)
0.0	0.0	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.0	0.0	GO:0002339	B cell selection(GO:0002339)
0.0	0.0	GO:0021524	visceral motor neuron differentiation(GO:0021524)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.0	GO:1902915	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.0	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.1	GO:0046874	quinolinate metabolic process(GO:0046874)
0.0	0.0	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.0	GO:0048340	paraxial mesoderm morphogenesis(GO:0048340)
0.0	0.0	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.1	GO:0032348	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0	0.1	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.1	GO:0070814	hydrogen sulfide biosynthetic process(GO:0070814)
0.0	0.0	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0	0.1	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.0	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.0	0.0	GO:2000409	positive regulation of T cell extravasation(GO:2000409)
0.0	0.1	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.1	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0	0.1	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.0	0.0	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0036022	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0	0.1	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.0	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0	0.0	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.0	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
0.0	0.0	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725)
0.0	0.0	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0	0.1	GO:0002477	antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.0	0.0	GO:0043201	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0	0.1	GO:0000820	regulation of glutamine family amino acid metabolic process(GO:0000820)
0.0	0.0	GO:0019230	proprioception(GO:0019230)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0035865	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0	0.2	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.0	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.0	0.0	GO:0034239	regulation of macrophage fusion(GO:0034239)
0.0	0.1	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0	0.1	GO:0006677	glycosylceramide metabolic process(GO:0006677)
0.0	0.0	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.0	GO:0018214	protein carboxylation(GO:0018214)
0.0	0.0	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0	0.0	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.0	0.0	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.0	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0	0.0	GO:1904222	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.0	GO:2000383	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0	0.0	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.1	GO:0002934	desmosome organization(GO:0002934)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0	0.0	GO:0071830	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.1	GO:0043486	histone exchange(GO:0043486)
0.0	0.1	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.0	GO:0055099	response to high density lipoprotein particle(GO:0055099)
0.0	0.1	GO:0086013	membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0	0.0	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.1	GO:0042297	vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.0	GO:2000832	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0	0.0	GO:0032261	purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0	0.0	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.0	0.0	GO:1900106	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0	0.0	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0	0.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.1	GO:0048617	embryonic foregut morphogenesis(GO:0048617)
0.0	0.0	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.0	GO:0006533	aspartate catabolic process(GO:0006533)
0.0	0.0	GO:0030070	insulin processing(GO:0030070)
0.0	0.1	GO:0051596	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.0	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015)
0.0	0.0	GO:0086023	adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0	0.0	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.0	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.0	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.0	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0043101	purine-containing compound salvage(GO:0043101)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.0	0.1	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.0	0.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.1	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.1	GO:0070939	Dsl1p complex(GO:0070939)
0.0	0.1	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.1	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.0	GO:0035838	growing cell tip(GO:0035838)
0.0	0.1	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0005726	perichromatin fibrils(GO:0005726)
0.0	0.1	GO:1990111	spermatoproteasome complex(GO:1990111)
0.0	0.1	GO:1990696	USH2 complex(GO:1990696)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.0	GO:0043511	inhibin complex(GO:0043511)
0.0	0.1	GO:0032437	cuticular plate(GO:0032437)
0.0	0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.0	GO:0097443	sorting endosome(GO:0097443)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0	0.1	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.0	0.2	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.2	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.1	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.1	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.2	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.2	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.1	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.0	0.2	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.1	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0052724	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.0	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.0	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	0.0	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.0	GO:0070699	type II activin receptor binding(GO:0070699)
0.0	0.0	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0	0.0	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.0	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.0	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.0	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.0	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.0	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.0	GO:0001602	pancreatic polypeptide receptor activity(GO:0001602)
0.0	0.0	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.0	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.0	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.0	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.0	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.1	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.0	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.0	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.4	GO:0005109	frizzled binding(GO:0005109)
0.0	0.0	GO:0071253	connexin binding(GO:0071253)
0.0	0.0	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.5	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.4	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.3	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.0	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex