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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Ep300

Z-value: 0.92

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Transcription factors associated with Ep300

Gene Symbol Gene ID Gene Info
Ep300
ENSMUSG00000055024.6 E1A binding protein p300

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr15_81586343_81586511Ep3002070.5742610.911.1e-02Click!
chr15_81585297_81585458Ep300200.8080490.641.7e-01Click!
chr15_81587767_81587940Ep30016330.204495-0.562.5e-01Click!
chr15_81586101_81586282Ep300290.5109940.374.8e-01Click!
chr15_81586614_81586807Ep3004900.446678-0.354.9e-01Click!

Activity of the Ep300 motif across conditions

Conditions sorted by the z-value of the Ep300 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_98148803_98148954 1.10 Omp
 olfactory marker protein
 3376
 0.19
chr19_45745506_45745808 0.95 Fgf8
 fibroblast growth factor 8
 2742
 0.18
chr11_4988618_4988782 0.66 Ap1b1
 adaptor protein complex AP-1, beta 1 subunit
 1766
 0.27
chr7_127815913_127816268 0.63 Gm45204
 predicted gene 45204
 2583
 0.1
chr1_133908470_133908621 0.62 Optc
 opticin
 546
 0.66
chr2_118529366_118529517 0.61 Bmf
 BCL2 modifying factor
 15146
 0.15
chr11_31824504_31824681 0.55 D630024D03Rik
 RIKEN cDNA D630024D03 gene
 68
 0.97
chr7_114290333_114290662 0.53 Psma1
 proteasome subunit alpha 1
 14379
 0.21
chr7_72498963_72499123 0.50 Gm37620
 predicted gene, 37620
 102946
 0.07
chr8_119444266_119444532 0.49 Necab2
 N-terminal EF-hand calcium binding protein 2
 2320
 0.23
chr1_4479698_4479869 0.47 Sox17
 SRY (sex determining region Y)-box 17
 13821
 0.14
chr1_132587567_132587718 0.45 Nfasc
 neurofascin
 502
 0.8
chr4_129795439_129795602 0.45 Ptp4a2
 protein tyrosine phosphatase 4a2
 15699
 0.12
chr9_66243421_66243631 0.45 Dapk2
 death-associated protein kinase 2
 22779
 0.2
chr7_27447795_27447954 0.45 Blvrb
 biliverdin reductase B (flavin reductase (NADPH))
 104
 0.61
chr11_6478757_6478908 0.44 Purb
 purine rich element binding protein B
 2915
 0.11
chr5_105698740_105698909 0.43 Lrrc8d
 leucine rich repeat containing 8D
 1145
 0.57
chr13_28757861_28758028 0.42 Mir6368
 microRNA 6368
 47071
 0.15
chr19_10266738_10266930 0.40 Dagla
 diacylglycerol lipase, alpha
 9963
 0.13
chr6_119674965_119675136 0.40 Erc1
 ELKS/RAB6-interacting/CAST family member 1
 52945
 0.15
chr19_49421746_49421913 0.39 Gm50444
 predicted gene, 50444
 132189
 0.06
chr8_128272968_128273154 0.39 Mir21c
 microRNA 21c
 5164
 0.3
chr5_33936341_33936510 0.39 Nelfa
 negative elongation factor complex member A, Whsc2
 12
 0.96
chr9_118944449_118944631 0.39 Ctdspl
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
 14673
 0.15
chr3_9599812_9599994 0.39 Zfp704
 zinc finger protein 704
 10182
 0.23
chr2_69228328_69228964 0.38 G6pc2
 glucose-6-phosphatase, catalytic, 2
 8618
 0.15
chr4_155421438_155421589 0.38 5830444B04Rik
 RIKEN cDNA 5830444B04 gene
 182
 0.71
chr8_115561082_115561286 0.37 4930488N15Rik
 RIKEN cDNA 4930488N15 gene
 24208
 0.21
chr5_138979896_138980396 0.37 Pdgfa
 platelet derived growth factor, alpha
 14135
 0.17
chr15_43477084_43477240 0.35 Emc2
 ER membrane protein complex subunit 2
 67
 0.58
chr14_50981405_50981569 0.35 Gm8518
 predicted gene 8518
 2551
 0.12
chr1_164631822_164631988 0.35 Gm37754
 predicted gene, 37754
 148
 0.96
chr9_66802090_66802293 0.34 BC050972
 cDNA sequence BC050972
 368
 0.78
chr15_64163681_64163861 0.34 Asap1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain1
 39965
 0.16
chr1_72827615_72827766 0.34 Igfbp2
 insulin-like growth factor binding protein 2
 2368
 0.33
chr10_92235111_92235286 0.34 Gm8512
 predicted gene 8512
 11724
 0.2
chr12_84190226_84190393 0.33 Gm19327
 predicted gene, 19327
 2503
 0.16
chr3_89422230_89422381 0.32 Shc1
 src homology 2 domain-containing transforming protein C1
 663
 0.44
chr17_13671853_13672032 0.32 2700054A10Rik
 RIKEN cDNA 2700054A10 gene
 3051
 0.19
chr19_23033456_23033617 0.31 Gm50136
 predicted gene, 50136
 27918
 0.18
chr1_165617212_165617387 0.30 Mpzl1
 myelin protein zero-like 1
 3320
 0.14
chr3_97156547_97156708 0.30 Acp6
 acid phosphatase 6, lysophosphatidic
 2150
 0.26
chr11_57983626_57984029 0.30 Gm12249
 predicted gene 12249
 10693
 0.15
chr11_4521480_4521785 0.29 Mtmr3
 myotubularin related protein 3
 6774
 0.2
chr4_133169582_133169763 0.29 Wasf2
 WAS protein family, member 2
 6329
 0.15
chr7_110689414_110689588 0.29 Gm21123
 predicted gene, 21123
 10233
 0.15
chr3_68493220_68493423 0.29 Schip1
 schwannomin interacting protein 1
 170
 0.96
chr16_28881932_28882083 0.28 Mb21d2
 Mab-21 domain containing 2
 45640
 0.17
chr19_47447791_47448053 0.28 Sh3pxd2a
 SH3 and PX domains 2A
 16325
 0.19
chr1_53931477_53931636 0.28 Gm24251
 predicted gene, 24251
 44615
 0.15
chr7_99164655_99164806 0.27 Dgat2
 diacylglycerol O-acyltransferase 2
 5376
 0.14
chr1_181860764_181860925 0.26 Gm5533
 predicted gene 5533
 7655
 0.14
chr5_92112862_92113049 0.26 Gm24931
 predicted gene, 24931
 5328
 0.13
chr6_99020013_99020438 0.26 Foxp1
 forkhead box P1
 7766
 0.28
chr11_62538516_62538686 0.26 Cenpv
 centromere protein V
 28
 0.95
chr15_82147771_82148080 0.26 Srebf2
 sterol regulatory element binding factor 2
 88
 0.94
chr11_95723019_95723183 0.26 Zfp652
 zinc finger protein 652
 10090
 0.12
chr5_117361300_117361465 0.25 Wsb2
 WD repeat and SOCS box-containing 2
 360
 0.77
chr13_68712216_68712409 0.25 Gm26929
 predicted gene, 26929
 97768
 0.06
chr4_98923398_98923571 0.25 Usp1
 ubiquitin specific peptidase 1
 326
 0.89
chr11_52257389_52257568 0.25 Tcf7
 transcription factor 7, T cell specific
 17399
 0.11
chr16_30925627_30925784 0.24 Gm46565
 predicted gene, 46565
 7635
 0.17
chr6_129254409_129254571 0.24 2310001H17Rik
 RIKEN cDNA 2310001H17 gene
 15765
 0.11
chr9_102864196_102864634 0.24 Ryk
 receptor-like tyrosine kinase
 4651
 0.18
chr4_8837559_8837760 0.24 Chd7
 chromodomain helicase DNA binding protein 7
 2663
 0.4
chr10_80823975_80824142 0.24 Oaz1
 ornithine decarboxylase antizyme 1
 2598
 0.1
chr5_115491812_115492014 0.24 Gm13836
 predicted gene 13836
 542
 0.51
chr3_85264828_85265142 0.24 1700036G14Rik
 RIKEN cDNA 1700036G14 gene
 52534
 0.14
chr7_132554584_132554735 0.24 Oat
 ornithine aminotransferase
 21059
 0.15
chr17_33524094_33524279 0.24 Adamts10
 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
 18
 0.97
chr2_170826881_170827076 0.23 Dok5
 docking protein 5
 95171
 0.08
chr15_28106057_28106225 0.23 Gm31458
 predicted gene, 31458
 12311
 0.17
chr2_126520012_126520163 0.23 Atp8b4
 ATPase, class I, type 8B, member 4
 19413
 0.19
chr17_80728516_80728734 0.23 Map4k3
 mitogen-activated protein kinase kinase kinase kinase 3
 140
 0.84
chr1_85526452_85526618 0.23 AC147806.2
 predicted 7592
 67
 0.59
chr19_41829665_41829837 0.23 Frat1
 frequently rearranged in advanced T cell lymphomas
 219
 0.91
chr7_104502188_104502379 0.23 Gm16464
 predicted gene 16464
 134
 0.91
chr8_126656365_126656543 0.23 Irf2bp2
 interferon regulatory factor 2 binding protein 2
 62468
 0.12
chr7_126494300_126494471 0.23 Atxn2l
 ataxin 2-like
 1009
 0.34
chr1_85649860_85650030 0.23 Sp100
 nuclear antigen Sp100
 43
 0.91
chr4_60503881_60504482 0.22 Gm13773
 predicted gene 13773
 1340
 0.3
chr2_60963495_60963646 0.22 Rbms1
 RNA binding motif, single stranded interacting protein 1
 378
 0.89
chr19_25387114_25387309 0.22 Kank1
 KN motif and ankyrin repeat domains 1
 8092
 0.22
chr6_146933231_146933413 0.22 1700034J05Rik
 RIKEN cDNA 1700034J05 gene
 21092
 0.14
chr17_86770158_86770337 0.22 Gm50008
 predicted gene, 50008
 3023
 0.24
chr5_52989351_52989502 0.22 5033403H07Rik
 RIKEN cDNA 5033403H07 gene
 2866
 0.21
chr2_84459790_84459967 0.22 Tfpi
 tissue factor pathway inhibitor
 1768
 0.34
chr8_94186443_94186638 0.22 Gm39228
 predicted gene, 39228
 3251
 0.13
chr11_116005461_116005624 0.22 Galk1
 galactokinase 1
 7177
 0.1
chr17_28257108_28257273 0.21 Ppard
 peroxisome proliferator activator receptor delta
 14518
 0.11
chr6_99171970_99172133 0.21 Foxp1
 forkhead box P1
 9033
 0.29
chr15_55819504_55819678 0.21 Sntb1
 syntrophin, basic 1
 86719
 0.08
chr11_49632419_49632570 0.21 Flt4
 FMS-like tyrosine kinase 4
 23231
 0.1
chr7_128740333_128740636 0.21 Mcmbp
 minichromosome maintenance complex binding protein
 2
 0.95
chr16_30067979_30068305 0.21 Hes1
 hes family bHLH transcription factor 1
 1804
 0.29
chr2_165855925_165856140 0.21 BC046401
 cDNA sequence BC046401
 1652
 0.28
chr11_70213843_70214036 0.21 Slc16a11
 solute carrier family 16 (monocarboxylic acid transporters), member 11
 29
 0.93
chr10_75835778_75835936 0.21 Gstt2
 glutathione S-transferase, theta 2
 976
 0.36
chr1_85199424_85199611 0.21 AC123856.1
 nuclear antigen Sp100 (Sp100) pseudogene
 96
 0.49
chr2_158179056_158179229 0.21 1700060C20Rik
 RIKEN cDNA 1700060C20 gene
 12866
 0.14
chr19_44997151_44997302 0.21 Sema4g
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
 5090
 0.11
chr17_87474571_87474777 0.21 Gm30938
 predicted gene, 30938
 932
 0.44
chr1_86479051_86479408 0.21 Rpl30-ps6
 ribosomal protein L30, pseudogene 6
 5570
 0.15
chr5_121917596_121917747 0.21 Cux2
 cut-like homeobox 2
 937
 0.54
chr16_34745072_34745237 0.20 Mylk
 myosin, light polypeptide kinase
 56
 0.98
chr12_8774307_8774470 0.20 Sdc1
 syndecan 1
 2585
 0.25
chr7_25705726_25706061 0.20 Ccdc97
 coiled-coil domain containing 97
 10213
 0.09
chr8_70659044_70659249 0.20 Pgpep1
 pyroglutamyl-peptidase I
 234
 0.83
chr6_52477529_52477702 0.20 1700094M24Rik
 RIKEN cDNA 1700094M24 gene
 14836
 0.16
chr12_84193897_84194204 0.20 Elmsan1
 ELM2 and Myb/SANT-like domain containing 1
 35
 0.95
chr8_111501860_111502048 0.20 Wdr59
 WD repeat domain 59
 11201
 0.17
chr7_99355809_99355967 0.20 Serpinh1
 serine (or cysteine) peptidase inhibitor, clade H, member 1
 2649
 0.21
chr7_15934182_15934342 0.20 Snord23
 small nucleolar RNA, C/D box 23
 4608
 0.11
chr1_85327350_85327504 0.20 Gm2619
 predicted gene 2619
 142
 0.87
chr4_58913611_58913779 0.20 Ecpas
 Ecm29 proteasome adaptor and scaffold
 946
 0.53
chr11_98777139_98777558 0.19 Nr1d1
 nuclear receptor subfamily 1, group D, member 1
 2015
 0.18
chr7_141456726_141456885 0.19 Pnpla2
 patatin-like phospholipase domain containing 2
 213
 0.8
chr18_35814838_35814999 0.19 Ube2d2a
 ubiquitin-conjugating enzyme E2D 2A
 13611
 0.09
chr9_71165149_71165695 0.19 Aqp9
 aquaporin 9
 200
 0.92
chr1_135311434_135311608 0.19 Timm17a
 translocase of inner mitochondrial membrane 17a
 176
 0.92
chr5_63964660_63964830 0.19 Rell1
 RELT-like 1
 4078
 0.19
chr12_111428451_111428628 0.19 Exoc3l4
 exocyst complex component 3-like 4
 194
 0.9
chr8_120248017_120248168 0.19 Gse1
 genetic suppressor element 1, coiled-coil protein
 19636
 0.16
chr3_95439810_95439972 0.19 Arnt
 aryl hydrocarbon receptor nuclear translocator
 5372
 0.1
chr8_22124952_22125137 0.19 Nek5
 NIMA (never in mitosis gene a)-related expressed kinase 5
 3
 0.97
chr13_75943581_75943755 0.19 Rhobtb3
 Rho-related BTB domain containing 3
 199
 0.9
chr9_48618793_48618948 0.19 Nnmt
 nicotinamide N-methyltransferase
 13717
 0.24
chr3_83953926_83954100 0.18 Tmem131l
 transmembrane 131 like
 10270
 0.26
chr13_30336361_30336758 0.18 Agtr1a
 angiotensin II receptor, type 1a
 115
 0.97
chr1_72827270_72827421 0.18 Igfbp2
 insulin-like growth factor binding protein 2
 2023
 0.37
chr19_41346470_41346772 0.18 Pik3ap1
 phosphoinositide-3-kinase adaptor protein 1
 38475
 0.17
chr5_30816231_30816420 0.18 Gm19409
 predicted gene, 19409
 705
 0.47
chr1_58145718_58146241 0.18 Gm24548
 predicted gene, 24548
 9109
 0.19
chr8_46386589_46386784 0.18 Gm45253
 predicted gene 45253
 798
 0.57
chr7_19211436_19211587 0.18 Gpr4
 G protein-coupled receptor 4
 1027
 0.3
chr18_20945707_20945922 0.18 Rnf125
 ring finger protein 125
 1189
 0.52
chr14_103099863_103100150 0.18 Fbxl3
 F-box and leucine-rich repeat protein 3
 440
 0.8
chr12_25416673_25416856 0.18 Gm36723
 predicted gene, 36723
 22009
 0.24
chr11_120694977_120695348 0.18 Aspscr1
 alveolar soft part sarcoma chromosome region, candidate 1 (human)
 5852
 0.07
chr4_108068074_108068398 0.17 Scp2
 sterol carrier protein 2, liver
 3127
 0.18
chr15_79012870_79013120 0.17 Gm10865
 predicted gene 10865
 1954
 0.13
chr7_127805019_127805207 0.17 9430064I24Rik
 RIKEN cDNA 9430064I24 gene
 2351
 0.11
chr11_102051638_102051976 0.17 Cd300lg
 CD300 molecule like family member G
 10298
 0.09
chr3_151424962_151425113 0.17 Adgrl4
 adhesion G protein-coupled receptor L4
 12850
 0.26
chr14_61861512_61861706 0.17 Gm47952
 predicted gene, 47952
 59767
 0.12
chr1_191906223_191906394 0.17 Slc30a1
 solute carrier family 30 (zinc transporter), member 1
 459
 0.69
chr1_36556661_36556829 0.17 Sema4c
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
 781
 0.34
chr6_88820995_88821174 0.17 Mgll
 monoglyceride lipase
 2046
 0.19
chr19_5663348_5663511 0.17 Sipa1
 signal-induced proliferation associated gene 1
 191
 0.84
chr11_106580051_106580208 0.17 Tex2
 testis expressed gene 2
 471
 0.82
chr8_119417331_119417482 0.17 Osgin1
 oxidative stress induced growth inhibitor 1
 16718
 0.14
chr15_84714847_84715041 0.17 Arhgap8
 Rho GTPase activating protein 8
 5108
 0.18
chr9_94538161_94538340 0.17 Dipk2a
 divergent protein kinase domain 2A
 169
 0.96
chr9_37613490_37613650 0.17 Spa17
 sperm autoantigenic protein 17
 0
 0.52
chr9_107657905_107658551 0.17 Slc38a3
 solute carrier family 38, member 3
 967
 0.31
chr3_90537214_90537374 0.17 S100a16
 S100 calcium binding protein A16
 21
 0.93
chr18_20058884_20059060 0.17 Dsc2
 desmocollin 2
 506
 0.84
chr1_191254917_191255072 0.17 Gm37074
 predicted gene, 37074
 5570
 0.14
chr1_155050256_155050434 0.17 Gm29282
 predicted gene 29282
 6834
 0.17
chr15_25940308_25940999 0.17 Retreg1
 reticulophagy regulator 1
 49
 0.98
chrX_12072855_12073006 0.17 Bcor
 BCL6 interacting corepressor
 7623
 0.27
chr4_134995142_134995297 0.17 Syf2
 SYF2 homolog, RNA splicing factor (S. cerevisiae)
 64209
 0.09
chr12_84052558_84052962 0.17 Acot3
 acyl-CoA thioesterase 3
 336
 0.69
chr3_57344020_57344185 0.16 Gm5276
 predicted gene 5276
 18286
 0.19
chr2_167375199_167375534 0.16 B4galt5
 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
 26183
 0.15
chr11_95827586_95827744 0.16 Phospho1
 phosphatase, orphan 1
 3098
 0.14
chr11_113008652_113008818 0.16 2610035D17Rik
 RIKEN cDNA 2610035D17 gene
 164342
 0.03
chr8_125337571_125337768 0.16 Gm16237
 predicted gene 16237
 110346
 0.06
chr8_111776845_111777015 0.16 Bcar1
 breast cancer anti-estrogen resistance 1
 33121
 0.14
chr15_99716487_99716652 0.16 Gpd1
 glycerol-3-phosphate dehydrogenase 1 (soluble)
 946
 0.3
chr3_85821987_85822152 0.16 Fam160a1
 family with sequence similarity 160, member A1
 4778
 0.2
chr4_32520450_32520651 0.16 Bach2
 BTB and CNC homology, basic leucine zipper transcription factor 2
 19045
 0.19
chr11_119045218_119045965 0.16 Cbx8
 chromobox 8
 4622
 0.17
chr2_30692293_30692476 0.16 Gm14486
 predicted gene 14486
 14373
 0.14
chr4_123412152_123412346 0.16 Macf1
 microtubule-actin crosslinking factor 1
 21
 0.97
chr10_4107762_4107973 0.16 Gm25515
 predicted gene, 25515
 3554
 0.27
chr4_106988955_106989270 0.16 Ssbp3
 single-stranded DNA binding protein 3
 22686
 0.15
chr11_97800088_97800264 0.16 Lasp1
 LIM and SH3 protein 1
 5
 0.94
chr5_125308383_125308534 0.16 Scarb1
 scavenger receptor class B, member 1
 3916
 0.18
chr10_118699777_118699944 0.16 Gm33337
 predicted gene, 33337
 15866
 0.18
chr15_83009671_83009841 0.16 Nfam1
 Nfat activating molecule with ITAM motif 1
 13327
 0.13
chr2_26578415_26578758 0.16 Egfl7
 EGF-like domain 7
 1428
 0.23
chr9_70318576_70318770 0.16 Mir5626
 microRNA 5626
 87080
 0.07
chr15_59717023_59717209 0.16 Gm20150
 predicted gene, 20150
 45003
 0.15
chr1_172312301_172312452 0.16 Igsf8
 immunoglobulin superfamily, member 8
 9
 0.96
chr12_102470243_102470394 0.16 Golga5
 golgi autoantigen, golgin subfamily a, 5
 1126
 0.47
chr10_20669582_20669754 0.15 Gm17230
 predicted gene 17230
 44033
 0.15
chr10_61313715_61314040 0.15 Rpl27a-ps1
 ribosomal protein L27A, pseudogene 1
 4047
 0.16
chr7_45782387_45782600 0.15 Lmtk3
 lemur tyrosine kinase 3
 1245
 0.21
chr4_124709066_124709229 0.15 Sf3a3
 splicing factor 3a, subunit 3
 5629
 0.09
chr2_24335745_24336056 0.15 Il1rn
 interleukin 1 receptor antagonist
 953
 0.46
chr10_80244946_80245115 0.15 Pwwp3a
 PWWP domain containing 3A, DNA repair factor
 2418
 0.12
chr12_108275649_108275819 0.15 Ccdc85c
 coiled-coil domain containing 85C
 309
 0.89
chr4_133556563_133556731 0.15 Gm23158
 predicted gene, 23158
 2302
 0.15
chr11_97435186_97435350 0.15 Arhgap23
 Rho GTPase activating protein 23
 1017
 0.5
chr9_32400631_32400981 0.15 Kcnj1
 potassium inwardly-rectifying channel, subfamily J, member 1
 6821
 0.18
chr16_35310487_35310877 0.15 Gm49706
 predicted gene, 49706
 12384
 0.15
chrX_13245137_13245293 0.15 2010308F09Rik
 RIKEN cDNA 2010308F09 gene
 2521
 0.17
chr7_25776793_25776952 0.15 Axl
 AXL receptor tyrosine kinase
 2194
 0.16
chr19_29142167_29142403 0.15 Mir101b
 microRNA 101b
 7006
 0.15

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Ep300

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0046149 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.4 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.1 0.3 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.1 0.3 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 0.3 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.1 0.2 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.1 0.2 GO:0071462 cellular response to water stimulus(GO:0071462)
0.1 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0045048 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.1 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0 0.1 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.1 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.4 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0044337 canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.0 0.1 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.4 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.1 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031)
0.0 0.1 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0 0.1 GO:0060913 cardiac cell fate determination(GO:0060913)
0.0 0.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.0 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.1 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.0 0.1 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.0 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:0071926 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0 0.1 GO:0015817 histidine transport(GO:0015817)
0.0 0.2 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:0000189 MAPK import into nucleus(GO:0000189)
0.0 0.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0072144 glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0009115 xanthine catabolic process(GO:0009115)
0.0 0.1 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0061144 alveolar secondary septum development(GO:0061144)
0.0 0.0 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.0 GO:1901321 positive regulation of heart induction(GO:1901321)
0.0 0.0 GO:0052151 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.1 GO:0021637 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 0.0 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.0 GO:0061643 chemorepulsion of axon(GO:0061643)
0.0 0.2 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.0 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.0 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.0 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.0 GO:2000054 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.0 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.0 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.0 0.0 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.0 GO:2000828 regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.0 GO:2000591 cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0 0.1 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.0 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.0 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.0 0.0 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.0 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.0 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.0 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.1 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.1 GO:0007614 short-term memory(GO:0007614)
0.0 0.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.0 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.0 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.0 GO:0018992 germ-line sex determination(GO:0018992)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.0 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0046697 decidualization(GO:0046697)
0.0 0.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.0 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.0 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.1 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.4 GO:0032021 NELF complex(GO:0032021)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.0 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.0 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.0 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.2 GO:0031711 bradykinin receptor binding(GO:0031711)
0.1 0.2 GO:0015205 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.1 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.1 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.2 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0004854 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0 0.0 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.0 GO:1990188 euchromatin binding(GO:1990188)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.0 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.0 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.0 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0016215 acyl-CoA desaturase activity(GO:0016215)
0.0 0.0 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.0 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation