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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Esr1

Z-value: 1.54

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Transcription factors associated with Esr1

Gene Symbol	Gene ID	Gene Info
Esr1 Ensembl NCBI MGI UniProt	ENSMUSG00000019768.10	estrogen receptor 1 (alpha)

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr10_4738419_4738590	Esr1	25853	0.244326	-0.93	7.9e-03	Click!
chr10_4612316_4612513	Esr1	393	0.883606	0.92	9.5e-03	Click!
chr10_4944861_4945066	Esr1	8437	0.271927	0.84	3.6e-02	Click!
chr10_4734095_4734259	Esr1	21526	0.256939	-0.83	4.0e-02	Click!
chr10_4776155_4776328	Esr1	63590	0.137267	-0.81	5.2e-02	Click!

Activity of the Esr1 motif across conditions

Conditions sorted by the z-value of the Esr1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr13_70590252_70590743	0.77	Ice1	interactor of little elongation complex ELL subunit 1	5747	0.2
chr7_97414019_97414355	0.74	Thrsp	thyroid hormone responsive	3332	0.16
chr15_84115082_84115482	0.62	Pnpla5	patatin-like phospholipase domain containing 5	7893	0.11
chr15_68245140_68245318	0.54	Zfat	zinc finger and AT hook domain containing	13558	0.2
chr1_186325513_186325749	0.54	Gm37491	predicted gene, 37491	21684	0.24
chr11_120810230_120810550	0.53	Fasn	fatty acid synthase	689	0.48
chr15_84113983_84114148	0.53	Gm46526	predicted gene, 46526	7407	0.11
chr5_149579767_149579923	0.49	Wdr95	WD40 repeat domain 95	1933	0.28
chr12_104343910_104344587	0.46	Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	5762	0.12
chr6_108665497_108666008	0.46	Bhlhe40	basic helix-loop-helix family, member e40	2706	0.23
chr3_89140809_89141081	0.45	Pklr	pyruvate kinase liver and red blood cell	4322	0.08
chr15_84132154_84132305	0.43	Gm33432	predicted gene, 33432	4925	0.12
chr11_60201956_60202762	0.43	Mir6922	microRNA 6922	32	0.63
chr8_93179442_93179779	0.42	Ces1d	carboxylesterase 1D	4321	0.16
chr2_127037418_127037582	0.42	Gm24081	predicted gene, 24081	3061	0.21
chr11_120817967_120818292	0.41	Fasn	fatty acid synthase	2674	0.13
chr8_46792440_46792615	0.40	Irf2	interferon regulatory factor 2	972	0.5
chr12_104087776_104088197	0.40	Serpina4-ps1	serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1	7337	0.1
chr9_74523907_74524058	0.39	Gm28622	predicted gene 28622	37396	0.17
chr15_25435984_25436493	0.38	Gm48956	predicted gene, 48956	9402	0.16
chr9_107307510_107307734	0.38	Gm17041	predicted gene 17041	5784	0.1
chr14_32708910_32709089	0.38	Gm28651	predicted gene 28651	22441	0.16
chr4_131722484_131723038	0.37	Gm16080	predicted gene 16080	12253	0.19
chr3_89142602_89142893	0.37	Pklr	pyruvate kinase liver and red blood cell	6124	0.07
chr5_130010252_130010587	0.37	Asl	argininosuccinate lyase	4303	0.13
chr15_58995280_58995901	0.35	4930544F09Rik	RIKEN cDNA 4930544F09 gene	11454	0.17
chr8_114150614_114151007	0.34	Nudt7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	17168	0.25
chr5_90639561_90639792	0.33	Rassf6	Ras association (RalGDS/AF-6) domain family member 6	811	0.61
chr19_10074283_10074444	0.33	Fads2	fatty acid desaturase 2	3176	0.18
chr14_7835138_7835309	0.33	Flnb	filamin, beta	17266	0.15
chr3_88418067_88418420	0.33	Slc25a44	solute carrier family 25, member 44	6864	0.07
chr1_21250628_21250912	0.32	Gsta3	glutathione S-transferase, alpha 3	2751	0.16
chr7_63923519_63923771	0.32	Klf13	Kruppel-like factor 13	1225	0.37
chr5_125479434_125479671	0.31	Gm27551	predicted gene, 27551	175	0.92
chr5_114246590_114246772	0.31	Acacb	acetyl-Coenzyme A carboxylase beta	1652	0.29
chr8_93192513_93192678	0.31	Gm45909	predicted gene 45909	1237	0.36
chr12_112591206_112591385	0.31	Inf2	inverted formin, FH2 and WH2 domain containing	2029	0.25
chr19_56521472_56521623	0.30	Dclre1a	DNA cross-link repair 1A	15835	0.17
chr5_33720967_33721166	0.30	Fgfr3	fibroblast growth factor receptor 3	608	0.58
chr2_58780980_58781131	0.29	Upp2	uridine phosphorylase 2	15730	0.2
chr7_138159973_138160131	0.29	Gm25798	predicted gene, 25798	58513	0.14
chr1_193227140_193227585	0.29	Hsd11b1	hydroxysteroid 11-beta dehydrogenase 1	11661	0.1
chr11_95039061_95039239	0.29	Pdk2	pyruvate dehydrogenase kinase, isoenzyme 2	1408	0.28
chrX_85734642_85734808	0.29	Gk	glycerol kinase	2885	0.21
chr14_61095439_61095613	0.29	Gm41168	predicted gene, 41168	32099	0.16
chr11_60196530_60196694	0.29	Mir6921	microRNA 6921	4005	0.13
chr7_97420499_97420665	0.28	Thrsp	thyroid hormone responsive	2852	0.18
chr5_125512652_125512844	0.28	Aacs	acetoacetyl-CoA synthetase	49	0.97
chr5_135090387_135090722	0.28	Mlxipl	MLX interacting protein-like	664	0.5
chr10_81542584_81542957	0.28	Gna11	guanine nucleotide binding protein, alpha 11	2420	0.11
chr19_26744877_26745028	0.28	Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	257	0.94
chrY_90783982_90784262	0.27	Gm47283	predicted gene, 47283	616	0.72
chr1_170137562_170137720	0.27	Uap1	UDP-N-acetylglucosamine pyrophosphorylase 1	6072	0.16
chr8_70832563_70832735	0.27	Arrdc2	arrestin domain containing 2	3938	0.09
chr7_99092352_99092512	0.27	Gm33882	predicted gene, 33882	2200	0.24
chr11_5912275_5912428	0.27	Gck	glucokinase	2773	0.16
chr9_106234809_106235123	0.27	Alas1	aminolevulinic acid synthase 1	2118	0.17
chr1_21261382_21261702	0.27	Gsta3	glutathione S-transferase, alpha 3	8021	0.11
chr2_181042289_181042677	0.26	Chrna4	cholinergic receptor, nicotinic, alpha polypeptide 4	1063	0.42
chr18_68491528_68491858	0.26	Gm50258	predicted gene, 50258	58900	0.1
chr11_60205641_60205948	0.26	Srebf1	sterol regulatory element binding transcription factor 1	318	0.81
chr8_35390018_35390398	0.26	Ppp1r3b	protein phosphatase 1, regulatory subunit 3B	13548	0.15
chr15_101191263_101191414	0.26	Mir6962	microRNA 6962	2531	0.16
chr5_23562685_23562882	0.26	Srpk2	serine/arginine-rich protein specific kinase 2	13413	0.19
chr7_83846298_83846449	0.26	Gm44993	predicted gene 44993	11774	0.1
chr17_79883308_79883515	0.26	Atl2	atlastin GTPase 2	12640	0.17
chr4_145023945_145024107	0.26	Vps13d	vacuolar protein sorting 13D	27008	0.2
chr6_55170175_55170376	0.26	Inmt	indolethylamine N-methyltransferase	4739	0.18
chr17_28028156_28028307	0.26	Anks1	ankyrin repeat and SAM domain containing 1	12544	0.11
chr5_30551378_30551537	0.25	Cib4	calcium and integrin binding family member 4	5621	0.14
chr11_120813788_120814608	0.25	Fasn	fatty acid synthase	1257	0.26
chr17_47455361_47455668	0.25	1700001C19Rik	RIKEN cDNA 1700001C19 gene	18138	0.11
chr18_80294645_80295296	0.25	Gm37015	predicted gene, 37015	8710	0.13
chr11_55026252_55026439	0.25	Anxa6	annexin A6	7070	0.17
chr3_58993764_58993930	0.25	Rpl13-ps6	ribosomal protein L13, pseudogene 6	6677	0.14
chr15_38290102_38290386	0.25	Klf10	Kruppel-like factor 10	8595	0.12
chr19_53225949_53226100	0.25	Add3	adducin 3 (gamma)	27978	0.12
chr4_95233136_95233413	0.25	Gm12708	predicted gene 12708	39912	0.16
chr12_69767338_69767491	0.25	Mir681	microRNA 681	3470	0.16
chr19_44415841_44416010	0.25	Gm50337	predicted gene, 50337	3685	0.17
chr17_31116179_31116343	0.25	Abcg1	ATP binding cassette subfamily G member 1	5296	0.13
chr3_51227403_51227633	0.25	Noct	nocturnin	3048	0.19
chr14_61680870_61681697	0.25	Gm37472	predicted gene, 37472	211	0.83
chr1_107937853_107938018	0.25	D830032E09Rik	RIKEN cDNA D830032E09 gene	1226	0.46
chrX_170009083_170009242	0.25	Erdr1	erythroid differentiation regulator 1	497	0.77
chr13_74019761_74019928	0.25	Gm6263	predicted gene 6263	290	0.84
chr3_118663369_118663520	0.25	Dpyd	dihydropyrimidine dehydrogenase	101258	0.07
chr4_120433714_120433865	0.25	Scmh1	sex comb on midleg homolog 1	13358	0.23
chr5_92169759_92169953	0.24	Uso1	USO1 vesicle docking factor	11533	0.11
chr18_64334411_64334587	0.24	St8sia3os	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3, opposite strand	793	0.6
chr7_112629934_112630091	0.24	Gm24154	predicted gene, 24154	11787	0.17
chr5_125526040_125526191	0.24	Tmem132b	transmembrane protein 132B	5659	0.17
chr9_108604052_108604227	0.24	Arih2	ariadne RBR E3 ubiquitin protein ligase 2	2471	0.1
chr11_78160013_78160257	0.24	Traf4	TNF receptor associated factor 4	5381	0.07
chr6_70790951_70791123	0.24	Rpia	ribose 5-phosphate isomerase A	966	0.51
chr8_93188530_93188681	0.24	Gm45909	predicted gene 45909	2753	0.19
chr12_80010993_80011167	0.24	Gm8275	predicted gene 8275	31229	0.14
chr13_63665698_63665976	0.24	Gm47387	predicted gene, 47387	4040	0.18
chr3_136802706_136802870	0.24	Gm44327	predicted gene, 44327	4410	0.24
chr17_85329254_85329420	0.23	Rpl31-ps16	ribosomal protein L31, pseudogene 16	169296	0.03
chr19_40191699_40191928	0.23	Gm5827	predicted gene 5827	775	0.57
chrX_13461389_13461908	0.23	Nyx	nyctalopin	4462	0.22
chr7_136457949_136458342	0.23	Gm36849	predicted gene, 36849	104781	0.07
chr10_81412487_81412833	0.23	Gm16104	predicted gene 16104	3085	0.08
chr13_101711494_101711645	0.23	Pik3r1	phosphoinositide-3-kinase regulatory subunit 1	9465	0.22
chr11_120817696_120817936	0.23	Fasn	fatty acid synthase	2361	0.15
chr12_69768209_69768388	0.23	Mir681	microRNA 681	4354	0.15
chr8_111724623_111724774	0.23	Bcar1	breast cancer anti-estrogen resistance 1	7407	0.18
chr11_104398389_104398540	0.23	Gm47315	predicted gene, 47315	26836	0.15
chr12_104084479_104084838	0.23	Serpina4-ps1	serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1	4009	0.12
chr2_170351585_170351736	0.23	Bcas1	breast carcinoma amplified sequence 1	1865	0.32
chr7_143755701_143755887	0.23	Osbpl5	oxysterol binding protein-like 5	1191	0.33
chr5_112287930_112288081	0.23	Tpst2	protein-tyrosine sulfotransferase 2	757	0.52
chr15_3453354_3453796	0.23	Ghr	growth hormone receptor	18069	0.26
chr4_136736025_136736176	0.23	Ephb2	Eph receptor B2	42060	0.13
chr17_81389463_81389664	0.23	Gm50044	predicted gene, 50044	18730	0.23
chr6_113649139_113649313	0.23	Gm43964	predicted gene, 43964	7705	0.07
chr17_46054574_46054727	0.23	Vegfa	vascular endothelial growth factor A	22281	0.12
chr19_44403590_44403745	0.22	Scd1	stearoyl-Coenzyme A desaturase 1	3023	0.2
chr11_120815283_120815743	0.22	Fasn	fatty acid synthase	58	0.94
chr9_74970668_74970899	0.22	Fam214a	family with sequence similarity 214, member A	5328	0.22
chr10_87931882_87932033	0.22	Tyms-ps	thymidylate synthase, pseudogene	34890	0.14
chr15_34497135_34497291	0.22	Pop1	processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)	1890	0.2
chr7_44465999_44466560	0.22	Aspdh	aspartate dehydrogenase domain containing	49	0.92
chr9_30851911_30852248	0.22	Adamts15	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15	57578	0.11
chr2_124609977_124610547	0.22	Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	34	0.99
chr2_75692386_75692604	0.22	Gm24996	predicted gene, 24996	5657	0.13
chr19_44396138_44396537	0.22	Scd1	stearoyl-Coenzyme A desaturase 1	10353	0.14
chr1_91440412_91440614	0.22	Per2	period circadian clock 2	9352	0.11
chr17_71251310_71251461	0.22	Emilin2	elastin microfibril interfacer 2	4021	0.18
chr5_99474871_99475183	0.22	Gm35172	predicted gene, 35172	33362	0.17
chr7_24928137_24928288	0.22	Arhgef1	Rho guanine nucleotide exchange factor (GEF) 1	4849	0.1
chr14_30541914_30542082	0.22	Tkt	transketolase	6361	0.15
chr16_18131401_18131565	0.22	Rtn4r	reticulon 4 receptor	3841	0.15
chr6_85931899_85932180	0.22	Nat8b-ps	N-acetyltransferase 8B, pseudogene	1340	0.22
chr19_3683068_3683219	0.22	Lrp5	low density lipoprotein receptor-related protein 5	3413	0.15
chrX_85734354_85734533	0.22	Gk	glycerol kinase	3167	0.2
chr1_21248120_21248286	0.22	Gsta3	glutathione S-transferase, alpha 3	5318	0.12
chr10_77441540_77441756	0.21	Gm35920	predicted gene, 35920	16269	0.15
chr3_87907622_87908270	0.21	Hdgf	heparin binding growth factor	412	0.71
chr4_53414447_53414950	0.21	Gm12496	predicted gene 12496	10668	0.21
chr6_98971942_98972103	0.21	Foxp1	forkhead box P1	31658	0.22
chr2_92375627_92375788	0.21	Pex16	peroxisomal biogenesis factor 16	148	0.87
chr9_48735314_48735473	0.21	Zbtb16	zinc finger and BTB domain containing 16	100552	0.07
chr3_99194778_99194940	0.21	Mir6481	microRNA 6481	4594	0.14
chr5_115585229_115585380	0.21	Gcn1	GCN1 activator of EIF2AK4	2907	0.14
chr6_17463758_17464495	0.21	Met	met proto-oncogene	19	0.98
chr1_193928644_193928965	0.21	Gm21362	predicted gene, 21362	61795	0.15
chr18_31704198_31704968	0.21	Gm50060	predicted gene, 50060	34132	0.13
chr1_91458780_91458942	0.21	Per2	period circadian clock 2	463	0.71
chr8_121970329_121970503	0.21	Gm17709	predicted gene, 17709	3406	0.13
chr16_23972646_23973216	0.21	Bcl6	B cell leukemia/lymphoma 6	551	0.74
chr5_125516996_125517147	0.21	Aacs	acetoacetyl-CoA synthetase	1828	0.29
chr5_102643765_102644161	0.21	Arhgap24	Rho GTPase activating protein 24	81010	0.11
chr11_120811562_120811973	0.21	Fasn	fatty acid synthase	2066	0.16
chr5_3465874_3466025	0.21	Cdk6	cyclin-dependent kinase 6	5000	0.16
chr12_103253060_103253247	0.21	Prima1	proline rich membrane anchor 1	11003	0.17
chr6_85095404_85095555	0.21	Gm43955	predicted gene, 43955	1448	0.21
chr10_12460934_12461269	0.21	Gm48798	predicted gene, 48798	39505	0.16
chr4_62723535_62723865	0.21	Gm11211	predicted gene 11211	3837	0.2
chr9_110132148_110132544	0.21	Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	309	0.86
chr3_51251752_51251903	0.21	Elf2	E74-like factor 2	8414	0.13
chr14_76409148_76409302	0.21	Tsc22d1	TSC22 domain family, member 1	5736	0.29
chr10_70173411_70173573	0.20	Ccdc6	coiled-coil domain containing 6	1017	0.58
chr2_164856590_164856794	0.20	Pltp	phospholipid transfer protein	104	0.92
chr3_94434889_94435130	0.20	Oaz3	ornithine decarboxylase antizyme 3	108	0.9
chr12_55440755_55440910	0.20	Psma6	proteasome subunit alpha 6	33449	0.13
chr4_134902978_134903198	0.20	Tmem50a	transmembrane protein 50A	11927	0.14
chr9_42218132_42218473	0.20	4930546K05Rik	RIKEN cDNA 4930546K05 gene	9071	0.19
chr15_59084103_59084254	0.20	Mtss1	MTSS I-BAR domain containing 1	2173	0.37
chrY_90800880_90801048	0.20	Gm47283	predicted gene, 47283	10513	0.18
chr7_45721720_45721904	0.20	Fam83e	family with sequence similarity 83, member E	592	0.41
chr16_24492681_24492874	0.20	Morf4l1-ps1	mortality factor 4 like 1, pseudogene 1	36617	0.16
chr11_89006377_89006528	0.20	Trim25	tripartite motif-containing 25	7076	0.12
chr4_122959046_122959235	0.20	Mfsd2a	major facilitator superfamily domain containing 2A	850	0.49
chr18_12859903_12860120	0.20	Osbpl1a	oxysterol binding protein-like 1A	240	0.91
chr11_60105576_60106348	0.20	Rai1	retinoic acid induced 1	785	0.59
chr12_57925148_57925300	0.20	Gm46329	predicted gene, 46329	25987	0.26
chr19_44386401_44386599	0.20	Scd1	stearoyl-Coenzyme A desaturase 1	20190	0.13
chr1_193287957_193288143	0.20	Gm37650	predicted gene, 37650	2839	0.15
chr9_66199300_66199667	0.20	Dapk2	death-associated protein kinase 2	21264	0.19
chr19_58369154_58369339	0.20	Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	85220	0.09
chr8_104787437_104787637	0.20	Gm45782	predicted gene 45782	1709	0.21
chr6_51680801_51680952	0.20	Gm38811	predicted gene, 38811	30205	0.19
chr2_92402720_92402871	0.20	Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	1532	0.23
chr6_100848852_100849036	0.20	Ppp4r2	protein phosphatase 4, regulatory subunit 2	3541	0.26
chr13_64187132_64187283	0.20	Habp4	hyaluronic acid binding protein 4	2704	0.17
chr1_134713567_134713742	0.20	Syt2	synaptotagmin II	4354	0.2
chr16_42998828_42999221	0.20	Ndufs5-ps	NADH:ubiquinone oxidoreductase core subunit S5, pseudogene	43393	0.16
chr11_120819707_120820136	0.20	Fasn	fatty acid synthase	3859	0.11
chr10_62647927_62648078	0.20	Ddx50	DEAD (Asp-Glu-Ala-Asp) box polypeptide 50	221	0.89
chr4_118290250_118290459	0.19	Ptprf	protein tyrosine phosphatase, receptor type, F	920	0.57
chr8_94390003_94390215	0.19	Herpud1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	681	0.52
chr15_62137137_62137308	0.19	Pvt1	Pvt1 oncogene	38193	0.2
chr11_77766621_77767221	0.19	Myo18a	myosin XVIIIA	185	0.93
chr14_56617767_56617918	0.19	Gm16573	predicted gene 16573	2655	0.22
chr11_120809505_120809952	0.19	Fasn	fatty acid synthase	27	0.95
chr4_148071783_148071944	0.19	Gm13201	predicted gene 13201	1153	0.29
chr11_16814206_16814660	0.19	Egfros	epidermal growth factor receptor, opposite strand	16269	0.21
chr3_76796116_76796283	0.19	Gm37290	predicted gene, 37290	25860	0.25

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Esr1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.2	0.5	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2	0.7	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.2	0.5	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	0.4	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.1	0.4	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.1	0.4	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1	0.2	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.1	0.3	GO:0030397	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1	0.3	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.1	0.4	GO:1903964	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1	0.3	GO:0010046	response to mycotoxin(GO:0010046)
0.1	0.2	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.1	0.2	GO:0061144	alveolar secondary septum development(GO:0061144)
0.1	0.2	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.1	0.3	GO:0097460	ferrous iron import into cell(GO:0097460)
0.1	0.2	GO:0060178	regulation of exocyst localization(GO:0060178)
0.1	0.2	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.1	0.1	GO:0072361	regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.1	0.2	GO:1904017	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1	0.2	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.1	0.1	GO:0033122	negative regulation of purine nucleotide catabolic process(GO:0033122)
0.1	0.2	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.2	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1	0.2	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.1	0.3	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.1	0.2	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.1	0.2	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	0.2	GO:0006742	NADP catabolic process(GO:0006742)
0.1	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.1	0.2	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.1	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.1	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.1	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0	0.1	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.2	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.2	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.3	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.3	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.2	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.4	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	1.1	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.0	0.1	GO:0060847	endothelial cell fate specification(GO:0060847)
0.0	0.4	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.0	0.2	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.0	0.0	GO:0045914	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.2	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.0	0.2	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.2	GO:0035865	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0	0.1	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.0	0.1	GO:0046098	guanine metabolic process(GO:0046098)
0.0	0.1	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.4	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.2	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.1	GO:0009804	coumarin metabolic process(GO:0009804)
0.0	0.1	GO:2000836	androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.0	0.2	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0	0.2	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0	0.0	GO:0060681	branch elongation involved in ureteric bud branching(GO:0060681)
0.0	0.1	GO:0072602	interleukin-4 secretion(GO:0072602)
0.0	0.1	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.0	0.3	GO:0042795	snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0	0.1	GO:0003383	apical constriction(GO:0003383)
0.0	0.1	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.2	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.0	0.1	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.2	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.4	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.2	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.0	0.1	GO:0009730	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
0.0	0.1	GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.0	0.0	GO:0034436	glycoprotein transport(GO:0034436)
0.0	0.1	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.2	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0009174	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.1	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.1	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.0	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.0	0.1	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0	0.1	GO:0032484	Ral protein signal transduction(GO:0032484)
0.0	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.0	0.1	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.2	GO:1901339	regulation of store-operated calcium channel activity(GO:1901339)
0.0	0.1	GO:0046167	glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0	0.2	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.1	GO:0051944	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0	0.3	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	0.1	GO:0034627	'de novo' NAD biosynthetic process(GO:0034627)
0.0	0.1	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	0.1	GO:0010528	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0	0.1	GO:0071314	cellular response to cocaine(GO:0071314)
0.0	0.1	GO:1903750	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0	0.1	GO:0090241	negative regulation of histone H4 acetylation(GO:0090241)
0.0	0.1	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0	0.1	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.0	0.1	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.0	0.1	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.0	0.0	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.0	0.1	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.1	GO:0071866	regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
0.0	0.1	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.0	0.1	GO:0061724	lipophagy(GO:0061724)
0.0	0.1	GO:0042374	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0	0.1	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0	0.1	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.0	0.1	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.0	0.1	GO:0046292	formaldehyde metabolic process(GO:0046292)
0.0	0.1	GO:1904970	brush border assembly(GO:1904970)
0.0	0.1	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.1	GO:1903798	regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.0	0.1	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0	0.2	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.1	GO:0090325	regulation of locomotion involved in locomotory behavior(GO:0090325)
0.0	0.1	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.0	0.2	GO:0051683	establishment of Golgi localization(GO:0051683)
0.0	0.1	GO:0071492	cellular response to UV-A(GO:0071492)
0.0	0.1	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.1	GO:0061010	gall bladder development(GO:0061010)
0.0	0.1	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.0	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.1	GO:0035754	B cell chemotaxis(GO:0035754)
0.0	0.0	GO:0050883	musculoskeletal movement, spinal reflex action(GO:0050883)
0.0	0.0	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.1	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0	0.2	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0	0.7	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.1	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.1	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.1	GO:0006382	adenosine to inosine editing(GO:0006382)
0.0	0.1	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.1	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.1	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.0	0.1	GO:0006059	hexitol metabolic process(GO:0006059)
0.0	0.3	GO:0071380	cellular response to prostaglandin E stimulus(GO:0071380)
0.0	0.1	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.0	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.0	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.0	0.1	GO:0061038	uterus morphogenesis(GO:0061038)
0.0	0.1	GO:0000087	mitotic M phase(GO:0000087)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.1	GO:0010963	regulation of L-arginine import(GO:0010963)
0.0	0.1	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.0	0.1	GO:0019471	4-hydroxyproline metabolic process(GO:0019471)
0.0	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.1	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0043174	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) nucleoside salvage(GO:0043174)
0.0	0.0	GO:1903069	regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.0	0.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.2	GO:0032986	nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.1	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0	0.0	GO:0034756	regulation of iron ion transport(GO:0034756)
0.0	0.0	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.0	0.1	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0	0.1	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.0	0.0	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.0	0.1	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.0	0.1	GO:0035188	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0	0.1	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0	0.0	GO:0070627	ferrous iron import(GO:0070627)
0.0	0.1	GO:0071038	nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038)
0.0	0.0	GO:0000430	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0	0.0	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.1	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0	0.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.0	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.0	0.1	GO:0051025	negative regulation of immunoglobulin secretion(GO:0051025)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.0	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.0	0.0	GO:0072194	kidney smooth muscle tissue development(GO:0072194)
0.0	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.0	GO:0033121	regulation of purine nucleotide catabolic process(GO:0033121)
0.0	0.1	GO:0070900	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0	0.2	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.0	0.1	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.0	0.1	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.0	0.1	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.0	GO:0046271	phenylpropanoid metabolic process(GO:0009698) phenylpropanoid catabolic process(GO:0046271)
0.0	0.1	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0	0.1	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.0	0.1	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.1	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0	0.1	GO:0044778	meiotic DNA integrity checkpoint(GO:0044778)
0.0	0.1	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.0	0.1	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.0	0.0	GO:0045345	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0	0.0	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.0	0.1	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.2	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.1	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.0	0.1	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0	0.1	GO:0043307	eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.0	0.1	GO:0060613	fat pad development(GO:0060613)
0.0	0.1	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0	0.0	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.1	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.1	GO:0098795	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0	0.1	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.0	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.0	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.0	GO:0006808	regulation of nitrogen utilization(GO:0006808)
0.0	0.2	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.0	0.0	GO:1901524	regulation of macromitophagy(GO:1901524)
0.0	0.0	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.0	0.0	GO:1900157	regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0	0.2	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.0	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.0	GO:0007208	phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.0	0.0	GO:2000425	regulation of apoptotic cell clearance(GO:2000425)
0.0	0.1	GO:0061042	vascular wound healing(GO:0061042)
0.0	0.1	GO:0046218	tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0	0.0	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
0.0	0.0	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.0	0.2	GO:0006458	'de novo' protein folding(GO:0006458) 'de novo' posttranslational protein folding(GO:0051084)
0.0	0.0	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.0	0.1	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0	0.0	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.0	GO:0060988	lipid tube assembly(GO:0060988)
0.0	0.1	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.0	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0	0.2	GO:2000780	negative regulation of double-strand break repair(GO:2000780)
0.0	0.0	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336)
0.0	0.0	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
0.0	0.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.0	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.2	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.0	GO:0002572	pro-T cell differentiation(GO:0002572)
0.0	0.0	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0	0.1	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.0	0.1	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.1	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.0	GO:0042525	tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
0.0	0.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.0	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.1	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.0	GO:2000468	regulation of peroxidase activity(GO:2000468)
0.0	0.1	GO:0014010	Schwann cell proliferation(GO:0014010)
0.0	0.0	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.0	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.1	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.0	GO:0036022	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0	0.1	GO:2000757	negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.1	GO:0030578	PML body organization(GO:0030578)
0.0	0.1	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.1	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production(GO:0032725)
0.0	0.4	GO:0021591	ventricular system development(GO:0021591)
0.0	0.3	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.1	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0	0.0	GO:0061738	late endosomal microautophagy(GO:0061738)
0.0	0.0	GO:0097167	circadian regulation of translation(GO:0097167)
0.0	0.0	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.0	GO:0031627	telomeric loop formation(GO:0031627)
0.0	0.0	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
0.0	0.0	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.0	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.0	0.0	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0	0.1	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.0	GO:0046618	drug export(GO:0046618)
0.0	0.0	GO:0060300	regulation of cytokine activity(GO:0060300)
0.0	0.1	GO:1903054	negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.1	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0	0.1	GO:0007343	egg activation(GO:0007343)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.1	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.2	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.0	GO:0045656	regulation of monocyte differentiation(GO:0045655) negative regulation of monocyte differentiation(GO:0045656)
0.0	0.1	GO:0060546	negative regulation of necroptotic process(GO:0060546)
0.0	0.2	GO:0003416	endochondral bone growth(GO:0003416)
0.0	0.1	GO:0035627	ceramide transport(GO:0035627)
0.0	0.0	GO:0002339	B cell selection(GO:0002339)
0.0	0.0	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0	0.1	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.0	0.3	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
0.0	0.0	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
0.0	0.0	GO:0061153	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0	0.1	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0	0.0	GO:0043652	engulfment of apoptotic cell(GO:0043652)
0.0	0.0	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.0	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.0	GO:0072205	metanephric collecting duct development(GO:0072205)
0.0	0.0	GO:0010042	response to manganese ion(GO:0010042)
0.0	0.3	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.0	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0	0.0	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.0	0.0	GO:2000510	positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0	0.0	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.0	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.0	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.0	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.0	0.0	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.0	GO:0021779	oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0070572	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.0	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.0	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.0	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.2	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.1	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0	0.1	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.0	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.0	GO:0030647	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.0	GO:0001887	selenium compound metabolic process(GO:0001887)
0.0	0.0	GO:0097694	establishment of RNA localization to telomere(GO:0097694)
0.0	0.3	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:0048733	sebaceous gland development(GO:0048733)
0.0	0.0	GO:0045054	constitutive secretory pathway(GO:0045054)
0.0	0.1	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.0	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.1	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0	0.0	GO:0015747	urate transport(GO:0015747)
0.0	0.0	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.0	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
0.0	0.4	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.0	GO:0030202	heparin metabolic process(GO:0030202)
0.0	0.0	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.1	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.0	0.1	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.0	GO:1905049	negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0	0.3	GO:0035019	somatic stem cell population maintenance(GO:0035019)
0.0	0.4	GO:0007584	response to nutrient(GO:0007584)
0.0	0.0	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0	0.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.0	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.1	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0	0.1	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.0	0.0	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	0.1	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.0	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.0	0.0	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.0	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	0.1	GO:0014733	regulation of skeletal muscle adaptation(GO:0014733)
0.0	0.0	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.0	0.0	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0	0.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.3	GO:0042587	glycogen granule(GO:0042587)
0.1	0.4	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.3	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.1	0.3	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.4	GO:0097433	dense body(GO:0097433)
0.1	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.4	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1	0.3	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.6	GO:0070852	cell body fiber(GO:0070852)
0.0	0.6	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.2	GO:0035363	histone locus body(GO:0035363)
0.0	0.2	GO:0031298	replication fork protection complex(GO:0031298)
0.0	0.2	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.1	GO:0097413	Lewy body(GO:0097413)
0.0	0.2	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.1	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0046691	intracellular canaliculus(GO:0046691)
0.0	0.1	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.2	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.1	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.1	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.0	GO:0032280	symmetric synapse(GO:0032280)
0.0	0.1	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.0	0.1	GO:0000938	GARP complex(GO:0000938)
0.0	0.1	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.1	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0097454	Schwann cell microvillus(GO:0097454)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	0.1	GO:0070939	Dsl1p complex(GO:0070939)
0.0	0.1	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0043293	apoptosome(GO:0043293)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.2	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.2	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.2	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.0	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.0	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.0	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.0	0.2	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.0	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.2	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.0	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.1	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0	0.0	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.5	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.1	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.1	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0	0.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.0	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.0	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.0	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.0	GO:0005610	laminin-5 complex(GO:0005610)
0.0	0.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.0	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.0	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.1	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.0	0.0	GO:0032021	NELF complex(GO:0032021)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.1	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.6	GO:0005811	lipid particle(GO:0005811)
0.0	0.0	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.0	GO:0031501	mannosyltransferase complex(GO:0031501)
0.0	0.0	GO:0005775	vacuolar lumen(GO:0005775)
0.0	0.0	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.0	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.2	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0043196	varicosity(GO:0043196)
0.0	0.1	GO:0044292	dendrite terminus(GO:0044292)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.4	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.1	1.2	GO:0004312	fatty acid synthase activity(GO:0004312)
0.1	0.2	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.4	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1	0.2	GO:0004771	sterol esterase activity(GO:0004771)
0.1	0.4	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.1	0.1	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.1	0.2	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.1	0.2	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.1	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.2	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	0.2	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.1	0.2	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1	0.3	GO:0004075	biotin carboxylase activity(GO:0004075)
0.1	0.2	GO:0030984	kininogen binding(GO:0030984)
0.1	0.2	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.2	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.2	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.2	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.2	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.0	0.4	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.2	GO:0033142	progesterone receptor binding(GO:0033142)
0.0	0.2	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.2	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.2	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.2	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.4	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.6	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.0	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.1	GO:0016880	acid-ammonia (or amide) ligase activity(GO:0016880)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0017002	activin-activated receptor activity(GO:0017002)
0.0	0.1	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.2	GO:0043426	MRF binding(GO:0043426)
0.0	0.2	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.1	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.0	0.1	GO:0035939	microsatellite binding(GO:0035939)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.2	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0034903	mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.2	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0	0.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.0	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.2	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.4	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.5	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.1	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	0.0	GO:0008948	oxaloacetate decarboxylase activity(GO:0008948)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.7	GO:0018733	3,4-dihydrocoumarin hydrolase activity(GO:0018733)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.3	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.1	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0070878	primary miRNA binding(GO:0070878)
0.0	0.2	GO:0051765	inositol tetrakisphosphate kinase activity(GO:0051765)
0.0	0.1	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.1	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.5	GO:0004119	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:1990254	keratin filament binding(GO:1990254)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.4	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.1	GO:0052796	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.1	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.2	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.2	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.1	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.2	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.1	GO:0019002	GMP binding(GO:0019002)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.2	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.1	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.0	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.0	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.1	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.0	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0	0.3	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.0	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.0	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.0	GO:0008147	structural constituent of bone(GO:0008147)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0002046	opsin binding(GO:0002046)
0.0	0.0	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.0	GO:0070905	serine binding(GO:0070905)
0.0	0.0	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.4	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.0	0.0	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.5	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.1	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.1	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.0	0.1	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.0	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.1	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.0	GO:0051430	corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0	0.1	GO:0097001	ceramide binding(GO:0097001)
0.0	0.0	GO:0019862	IgA binding(GO:0019862)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.0	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.0	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.0	0.0	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.0	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.2	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.0	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.1	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.0	0.1	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0	0.1	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.1	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.0	GO:0035514	DNA demethylase activity(GO:0035514)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.0	GO:0005415	nucleoside:sodium symporter activity(GO:0005415)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.0	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.0	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0070573	metallodipeptidase activity(GO:0070573)
0.0	0.1	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.3	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.1	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	0.1	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.0	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.0	0.0	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0	0.1	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.1	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.0	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.0	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.0	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	1.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	1.2	ST ADRENERGIC	Adrenergic Pathway
0.0	0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.4	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	1.1	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.3	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.8	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.4	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.0	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.7	PID FGF PATHWAY	FGF signaling pathway
0.0	0.2	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.5	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.3	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.5	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.4	PID ATM PATHWAY	ATM pathway
0.0	0.4	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.2	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.3	PID AURORA B PATHWAY	Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.7	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.4	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.1	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	1.0	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.8	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.0	REACTOME SIGNALING BY INSULIN RECEPTOR	Genes involved in Signaling by Insulin receptor
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.1	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.5	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.1	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.1	REACTOME SIGNALING BY FGFR1 MUTANTS	Genes involved in Signaling by FGFR1 mutants
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.0	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.0	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.1	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.1	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.1	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.2	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.1	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.1	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)

Results for Esr1

Z-value: 1.54

Motif logo

Transcription factors associated with Esr1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Esr1 motif across conditions

Conditions sorted by the z-value of the Esr1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Esr1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: