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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Esrrg

Z-value: 2.39

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Transcription factors associated with Esrrg

Gene Symbol	Gene ID	Gene Info
Esrrg Ensembl NCBI MGI UniProt	ENSMUSG00000026610.7	estrogen-related receptor gamma

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr1_187593505_187593668	Esrrg	15205	0.222689	0.71	1.1e-01	Click!
chr1_187609518_187609683	Esrrg	96	0.975594	-0.70	1.2e-01	Click!
chr1_187979615_187979766	Esrrg	18137	0.228684	0.69	1.3e-01	Click!
chr1_187593835_187593993	Esrrg	14877	0.223204	0.66	1.5e-01	Click!
chr1_187608439_187608751	Esrrg	196	0.954704	-0.63	1.8e-01	Click!

Activity of the Esrrg motif across conditions

Conditions sorted by the z-value of the Esrrg motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_6012474_6012958	4.83	Camk2b	calcium/calmodulin-dependent protein kinase II, beta	12268	0.17
chr12_51259911_51260071	2.82	Rps11-ps4	ribosomal protein S11, pseudogene 4	37496	0.18
chr13_46051322_46051732	2.72	Gm45949	predicted gene, 45949	9070	0.25
chr7_25220574_25220762	2.40	Dedd2	death effector domain-containing DNA binding protein 2	53	0.89
chr16_18131401_18131565	2.35	Rtn4r	reticulon 4 receptor	3841	0.15
chr15_53163055_53163223	2.19	Ext1	exostosin glycosyltransferase 1	33116	0.24
chr15_55043394_55043818	2.01	Taf2	TATA-box binding protein associated factor 2	2560	0.24
chr4_125936153_125936304	1.89	2610028E06Rik	RIKEN cDNA 2610028E06 gene	13811	0.22
chr3_18165162_18165350	1.88	Gm23686	predicted gene, 23686	12369	0.23
chr3_51251752_51251903	1.87	Elf2	E74-like factor 2	8414	0.13
chr8_76151909_76152060	1.76	Gm45742	predicted gene 45742	34957	0.2
chr1_91410552_91410703	1.53	Hes6	hairy and enhancer of split 6	2581	0.16
chr15_3401983_3402134	1.53	Ghr	growth hormone receptor	69586	0.11
chr2_15610043_15610194	1.49	Gm37595	predicted gene, 37595	79005	0.1
chr8_93176743_93176912	1.43	Ces1d	carboxylesterase 1D	1538	0.3
chr9_74849291_74849770	1.42	Gm16551	predicted gene 16551	535	0.61
chr6_51709759_51710069	1.39	Gm38811	predicted gene, 38811	1167	0.59
chr19_37074413_37074612	1.38	Gm22714	predicted gene, 22714	74650	0.08
chr19_10087853_10088030	1.35	Fads2	fatty acid desaturase 2	775	0.57
chr4_109317363_109317529	1.30	Eps15	epidermal growth factor receptor pathway substrate 15	8295	0.21
chr8_93108415_93108795	1.26	Ces1c	carboxylesterase 1C	15924	0.14
chr9_74885383_74885534	1.25	Onecut1	one cut domain, family member 1	18974	0.14
chr2_34486208_34486368	1.23	Mapkap1	mitogen-activated protein kinase associated protein 1	41941	0.13
chr17_84734402_84734930	1.22	Lrpprc	leucine-rich PPR-motif containing	3482	0.21
chr7_118151938_118152113	1.22	Gm25683	predicted gene, 25683	1455	0.35
chr11_16559343_16559548	1.21	Akt2-ps	thymoma viral proto-oncogene 2, pseudogene	44912	0.13
chr7_97414546_97414708	1.21	Thrsp	thyroid hormone responsive	2892	0.18
chr15_84115082_84115482	1.20	Pnpla5	patatin-like phospholipase domain containing 5	7893	0.11
chr1_21258115_21258471	1.19	Gsta3	glutathione S-transferase, alpha 3	4772	0.12
chr4_108047692_108047932	1.18	Scp2	sterol carrier protein 2, liver	67	0.96
chr3_60553127_60553297	1.14	Gm37589	predicted gene, 37589	17461	0.2
chr3_146809629_146809780	1.14	Prkacb	protein kinase, cAMP dependent, catalytic, beta	3256	0.21
chr14_8665751_8665920	1.13	4930452B06Rik	RIKEN cDNA 4930452B06 gene	404	0.58
chr19_37248362_37248513	1.12	Gm25268	predicted gene, 25268	14953	0.13
chr3_122033420_122033571	1.12	Gm42544	predicted gene 42544	9665	0.17
chr1_140267910_140268090	1.10	Gm37777	predicted gene, 37777	1513	0.46
chr17_25127135_25127453	1.09	Clcn7	chloride channel, voltage-sensitive 7	6097	0.1
chr12_72955142_72955307	1.06	Gm38170	predicted gene, 38170	4329	0.17
chr4_19713524_19713754	1.06	Wwp1	WW domain containing E3 ubiquitin protein ligase 1	4646	0.23
chr3_138222370_138222521	1.05	Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	974	0.44
chr1_9658480_9658648	1.04	Gm29520	predicted gene 29520	17982	0.13
chr1_169165809_169166010	1.04	Mir6354	microRNA 6354	146820	0.04
chr10_87559764_87559972	1.02	Pah	phenylalanine hydroxylase	13195	0.22
chr4_45769718_45769869	1.01	Gm12409	predicted gene 12409	5570	0.15
chr2_20912957_20913368	1.00	Arhgap21	Rho GTPase activating protein 21	1532	0.43
chr3_27283790_27284040	0.98	Gm37191	predicted gene, 37191	5855	0.2
chr14_118008711_118008863	0.98	Dct	dopachrome tautomerase	18748	0.19
chr15_81813046_81813197	0.98	Tef	thyrotroph embryonic factor	962	0.38
chr11_120819185_120819682	0.97	Fasn	fatty acid synthase	3978	0.11
chr3_127891231_127891382	0.97	Fam241a	family with sequence similarity 241, member A	4982	0.14
chr2_52370968_52371150	0.97	Neb	nebulin	3529	0.18
chr8_93171692_93172126	0.96	Ces1d	carboxylesterase 1D	1934	0.25
chr5_30551378_30551537	0.96	Cib4	calcium and integrin binding family member 4	5621	0.14
chr9_97528033_97528234	0.95	Gm25607	predicted gene, 25607	88506	0.09
chr11_115384715_115384871	0.95	Cdr2l	cerebellar degeneration-related protein 2-like	2877	0.12
chr14_58511323_58511474	0.95	Gm25614	predicted gene, 25614	139002	0.05
chr15_10212461_10212612	0.95	Prlr	prolactin receptor	929	0.7
chr19_10122021_10122209	0.95	Fads2	fatty acid desaturase 2	20369	0.12
chr17_45924651_45924805	0.94	Gm49805	predicted gene, 49805	37131	0.12
chr11_84186498_84186677	0.93	Gm37391	predicted gene, 37391	3006	0.22
chr7_126274454_126274655	0.93	Sbk1	SH3-binding kinase 1	1154	0.36
chr19_11977402_11977711	0.92	Osbp	oxysterol binding protein	11615	0.09
chr19_10055313_10055464	0.91	Fads3	fatty acid desaturase 3	864	0.49
chr4_150660019_150660333	0.91	Slc45a1	solute carrier family 45, member 1	8002	0.19
chr13_109536856_109537007	0.91	Pde4d	phosphodiesterase 4D, cAMP specific	44474	0.21
chr5_111457663_111457990	0.90	Gm43119	predicted gene 43119	34237	0.14
chr18_84091948_84092139	0.88	Zadh2	zinc binding alcohol dehydrogenase, domain containing 2	3372	0.19
chr7_80973329_80973598	0.88	Gm18782	predicted gene, 18782	6430	0.11
chr1_119479796_119479954	0.88	Ralb	v-ral simian leukemia viral oncogene B	1796	0.28
chr3_79536418_79536569	0.87	Fnip2	folliculin interacting protein 2	4617	0.17
chr4_8682871_8683217	0.87	Chd7	chromodomain helicase DNA binding protein 7	7362	0.24
chr5_91245207_91245388	0.87	Gm23092	predicted gene, 23092	27293	0.18
chr9_83726172_83726335	0.86	Gm2109	predicted gene 2109	34778	0.15
chr6_128370129_128370297	0.86	Foxm1	forkhead box M1	746	0.35
chr19_40994666_40994817	0.86	Blnk	B cell linker	206	0.94
chr8_125401526_125401692	0.86	Sipa1l2	signal-induced proliferation-associated 1 like 2	91101	0.09
chr19_14655923_14656095	0.85	Gm37997	predicted gene, 37997	2658	0.36
chr17_3794450_3794609	0.85	Nox3	NADPH oxidase 3	98268	0.08
chr7_16576791_16576945	0.83	Gm29443	predicted gene 29443	36956	0.07
chr2_20909275_20909427	0.83	Arhgap21	Rho GTPase activating protein 21	5343	0.23
chr7_97740831_97740990	0.82	Aqp11	aquaporin 11	2621	0.23
chr2_72158173_72158334	0.82	Rapgef4os1	Rap guanine nucleotide exchange factor (GEF) 4, opposite strand 1	9457	0.2
chr19_31895059_31895210	0.82	Gm19241	predicted gene, 19241	18510	0.2
chr2_34828383_34828580	0.82	Fbxw2	F-box and WD-40 domain protein 2	2170	0.17
chr17_24849573_24849724	0.82	Fahd1	fumarylacetoacetate hydrolase domain containing 1	716	0.34
chr4_41493396_41493579	0.82	Myorg	myogenesis regulating glycosidase (putative)	9181	0.1
chr8_33950546_33950701	0.81	Rbpms	RNA binding protein gene with multiple splicing	20760	0.14
chr18_33460517_33460699	0.81	Nrep	neuronal regeneration related protein	2827	0.28
chr2_31476173_31476462	0.81	Ass1	argininosuccinate synthetase 1	6110	0.2
chr1_186482290_186482447	0.80	A730004F24Rik	RIKEN cDNA A730004F24 gene	76104	0.1
chr3_107238884_107239100	0.80	Prok1	prokineticin 1	340	0.83
chr4_120822443_120822622	0.80	Nfyc	nuclear transcription factor-Y gamma	3152	0.16
chr11_95223164_95223328	0.78	Gm11515	predicted gene 11515	2386	0.22
chr10_91142235_91142389	0.78	Tmpo	thymopoietin	9521	0.15
chr5_30610413_30610591	0.78	Kcnk3	potassium channel, subfamily K, member 3	10871	0.13
chr13_51095199_51095382	0.78	Spin1	spindlin 1	5590	0.26
chr8_119897958_119898164	0.77	Usp10	ubiquitin specific peptidase 10	12299	0.15
chr5_113015757_113016135	0.77	Grk3	G protein-coupled receptor kinase 3	155	0.94
chr1_33964721_33964878	0.77	Gm28631	predicted gene 28631	1114	0.42
chr1_136431704_136431862	0.76	Ddx59	DEAD (Asp-Glu-Ala-Asp) box polypeptide 59	619	0.67
chr5_66421556_66421781	0.76	Gm43792	predicted gene 43792	10458	0.16
chr7_64347926_64348121	0.75	Gm20457	predicted gene 20457	2059	0.24
chr5_129948581_129948919	0.75	Gm42986	predicted gene 42986	3170	0.14
chr5_151246921_151247115	0.75	5430435K18Rik	RIKEN cDNA 5430435K18 gene	5287	0.21
chr15_95835869_95836082	0.75	Gm17546	predicted gene, 17546	5903	0.16
chr18_3616477_3616628	0.75	Gm50091	predicted gene, 50091	271	0.93
chr7_128663206_128663357	0.74	Inpp5f	inositol polyphosphate-5-phosphatase F	399	0.76
chr5_114161428_114161724	0.74	Acacb	acetyl-Coenzyme A carboxylase beta	3942	0.16
chr10_80255545_80256082	0.74	Ndufs7	NADH:ubiquinone oxidoreductase core subunit S7	2498	0.11
chr5_123067857_123068009	0.74	Tmem120b	transmembrane protein 120B	482	0.61
chr6_85095404_85095555	0.74	Gm43955	predicted gene, 43955	1448	0.21
chr6_120978477_120978636	0.73	Mical3	microtubule associated monooxygenase, calponin and LIM domain containing 3	4162	0.17
chr3_118357703_118357854	0.72	Gm26871	predicted gene, 26871	72546	0.09
chr3_27155320_27155479	0.72	1700125G22Rik	RIKEN cDNA 1700125G22 gene	1373	0.32
chr9_74894770_74895613	0.71	Onecut1	one cut domain, family member 1	28707	0.13
chr10_95420100_95420251	0.71	5730420D15Rik	RIKEN cDNA 5730420D15 gene	2800	0.17
chr18_11978675_11978853	0.71	Gm49968	predicted gene, 49968	65633	0.1
chr11_118256534_118256685	0.70	Usp36	ubiquitin specific peptidase 36	6675	0.17
chr11_98297732_98297887	0.70	Gm20644	predicted gene 20644	12427	0.09
chr14_88428338_88428489	0.70	Gm48930	predicted gene, 48930	12388	0.18
chr5_63789277_63789441	0.70	Nwd2	NACHT and WD repeat domain containing 2	11103	0.21
chr11_4191268_4191561	0.69	Tbc1d10a	TBC1 domain family, member 10a	4592	0.11
chr13_51582325_51582477	0.69	Shc3	src homology 2 domain-containing transforming protein C3	12914	0.2
chr13_44408792_44409069	0.69	Gm33958	predicted gene, 33958	17813	0.15
chr12_101990840_101991003	0.69	Ndufb1-ps	NADH:ubiquinone oxidoreductase subunit B1	13853	0.15
chr11_16860736_16860887	0.68	Egfr	epidermal growth factor receptor	17339	0.19
chr2_18435403_18435565	0.68	Dnajc1	DnaJ heat shock protein family (Hsp40) member C1	42654	0.16
chr1_92049227_92049392	0.68	Gm37036	predicted gene, 37036	27212	0.18
chr7_97741045_97741235	0.68	Aqp11	aquaporin 11	2851	0.22
chr3_146504144_146504452	0.68	Rpf1	ribosome production factor 1 homolog	3926	0.15
chr17_91025383_91025534	0.68	Gm47307	predicted gene, 47307	62948	0.1
chr11_46695519_46695670	0.68	Timd2	T cell immunoglobulin and mucin domain containing 2	3368	0.19
chr7_97414019_97414355	0.67	Thrsp	thyroid hormone responsive	3332	0.16
chr9_35041628_35041805	0.67	St3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	14078	0.17
chr6_140605976_140606131	0.67	Gm44013	predicted gene, 44013	16370	0.17
chr6_121220325_121220521	0.67	Gm15856	predicted gene 15856	5730	0.13
chr17_83178597_83178785	0.67	Pkdcc	protein kinase domain containing, cytoplasmic	36601	0.16
chr16_49530410_49530589	0.67	Gm6931	predicted gene 6931	105693	0.07
chr6_54465003_54465192	0.66	Wipf3	WAS/WASL interacting protein family, member 3	6905	0.17
chr8_22284028_22284212	0.66	Tpte	transmembrane phosphatase with tensin homology	679	0.65
chr10_108111233_108111440	0.66	Gm47999	predicted gene, 47999	31096	0.2
chr15_67925007_67925168	0.65	Gm49409	predicted gene, 49409	17717	0.25
chr1_162969759_162969918	0.65	Gm37273	predicted gene, 37273	13176	0.15
chr2_129197178_129197487	0.65	Gm4430	predicted gene 4430	206	0.85
chrX_144526234_144526385	0.65	Gm15071	predicted gene 15071	26982	0.17
chr18_77783204_77783362	0.65	Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1	3451	0.17
chr2_51137514_51137725	0.65	Rnd3	Rho family GTPase 3	11475	0.25
chr5_111509539_111510088	0.65	C130026L21Rik	RIKEN cDNA C130026L21 gene	71609	0.09
chr18_81346372_81346701	0.65	Gm30192	predicted gene, 30192	81828	0.09
chr9_74964831_74965084	0.64	Fam214a	family with sequence similarity 214, member A	11154	0.2
chr14_30254871_30255032	0.64	Gm47570	predicted gene, 47570	47213	0.13
chr11_26477161_26477486	0.64	Fancl	Fanconi anemia, complementation group L	8988	0.25
chr12_31725655_31725812	0.64	Gpr22	G protein-coupled receptor 22	11786	0.15
chr13_31340004_31340178	0.63	Gm11373	predicted gene 11373	9324	0.16
chr18_53814421_53814597	0.63	Csnk1g3	casein kinase 1, gamma 3	47613	0.17
chr1_187653528_187653711	0.63	Gm36388	predicted gene, 36388	1795	0.36
chr16_37654680_37654855	0.63	Ndufb4	NADH:ubiquinone oxidoreductase subunit B4	314	0.88
chr4_95050669_95051233	0.63	Junos	jun proto-oncogene, opposite strand	583	0.54
chr14_7941524_7941724	0.63	Gm45521	predicted gene 45521	15664	0.17
chr15_73183404_73183576	0.62	Ago2	argonaute RISC catalytic subunit 2	1445	0.42
chr3_34076440_34076601	0.62	Dnajc19	DnaJ heat shock protein family (Hsp40) member C19	3660	0.16
chr13_41214741_41215042	0.62	Elovl2	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2	5271	0.14
chr8_13027428_13027590	0.62	F7	coagulation factor VII	1475	0.23
chr6_119387798_119387973	0.62	Adipor2	adiponectin receptor 2	801	0.67
chr15_97022881_97023203	0.61	Slc38a4	solute carrier family 38, member 4	2720	0.38
chr1_102517589_102517767	0.61	Gm20281	predicted gene, 20281	58756	0.14
chr4_108831104_108831282	0.60	Btf3l4	basic transcription factor 3-like 4	642	0.62
chr11_16859692_16859843	0.60	Egfr	epidermal growth factor receptor	18383	0.18
chr12_108252308_108252530	0.60	Ccdc85c	coiled-coil domain containing 85C	22714	0.16
chr12_103687063_103687254	0.59	Serpina1f	serine (or cysteine) peptidase inhibitor, clade A, member 1F	7508	0.1
chr13_54594427_54594595	0.59	Higd2a	HIG1 domain family, member 2A	4304	0.11
chr1_160397801_160398023	0.59	Rabgap1l	RAB GTPase activating protein 1-like	43955	0.13
chr6_48903578_48903740	0.59	Aoc1	amine oxidase, copper-containing 1	1327	0.24
chr5_104033018_104033412	0.59	Hsd17b11	hydroxysteroid (17-beta) dehydrogenase 11	11296	0.1
chr16_32698159_32698320	0.58	Tnk2	tyrosine kinase, non-receptor, 2	17425	0.13
chr9_7989448_7989599	0.58	Yap1	yes-associated protein 1	12180	0.15
chr7_16411592_16411766	0.58	Zc3h4	zinc finger CCCH-type containing 4	3166	0.12
chr4_104986643_104986823	0.58	Gm12721	predicted gene 12721	16604	0.24
chr11_120815283_120815743	0.58	Fasn	fatty acid synthase	58	0.94
chr17_57276255_57276622	0.57	Vav1	vav 1 oncogene	2662	0.18
chr2_152359606_152359999	0.57	Gm14165	predicted gene 14165	6187	0.1
chr14_74924352_74924521	0.57	Gm10847	predicted gene 10847	2009	0.34
chr6_145853246_145853409	0.57	Gm43909	predicted gene, 43909	9970	0.17
chr13_34188591_34188742	0.57	Slc22a23	solute carrier family 22, member 23	4865	0.17
chr9_44085495_44085674	0.56	Usp2	ubiquitin specific peptidase 2	634	0.45
chr5_66015370_66015813	0.55	9130230L23Rik	RIKEN cDNA 9130230L23 gene	11306	0.12
chr14_59443633_59443793	0.55	Cab39l	calcium binding protein 39-like	2732	0.21
chr15_3533289_3533452	0.55	Ghr	growth hormone receptor	48472	0.16
chr2_32073660_32073977	0.55	Fam78a	family with sequence similarity 78, member A	5534	0.12
chr10_99681243_99681404	0.54	Gm35101	predicted gene, 35101	11809	0.17
chr9_102861148_102861344	0.54	Ryk	receptor-like tyrosine kinase	7820	0.16
chr15_56608723_56608891	0.54	Has2os	hyaluronan synthase 2, opposite strand	81137	0.1
chr19_4513822_4513989	0.54	Pcx	pyruvate carboxylase	1749	0.26
chr5_122289450_122289732	0.54	Pptc7	PTC7 protein phosphatase homolog	5226	0.12
chr13_63299010_63299206	0.54	Aopep	aminopeptidase O	315	0.68
chr17_88297408_88297825	0.54	1700116H05Rik	RIKEN cDNA 1700116H05 gene	7762	0.21
chr18_84895114_84895284	0.54	Cyb5a	cytochrome b5 type A (microsomal)	17598	0.15
chr9_103999271_103999461	0.54	Gm33054	predicted gene, 33054	2973	0.16
chr1_30940674_30940865	0.54	Ptp4a1	protein tyrosine phosphatase 4a1	3535	0.2
chr12_103961833_103961992	0.53	Serpina1e	serine (or cysteine) peptidase inhibitor, clade A, member 1E	2937	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Esrrg

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.3	GO:0032377	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.3	0.9	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.3	0.9	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.3	0.9	GO:0006068	ethanol catabolic process(GO:0006068)
0.3	0.8	GO:0038161	prolactin signaling pathway(GO:0038161)
0.2	0.7	GO:0051684	maintenance of Golgi location(GO:0051684)
0.2	0.6	GO:0010046	response to mycotoxin(GO:0010046)
0.2	0.7	GO:0090427	activation of meiosis(GO:0090427)
0.2	0.5	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2	0.6	GO:0046449	creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.2	0.5	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.1	0.4	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
0.1	0.6	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.1	0.4	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.1	0.5	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1	0.4	GO:0034287	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1	0.4	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.4	GO:0023041	neuronal signal transduction(GO:0023041)
0.1	0.3	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.1	0.3	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.1	0.4	GO:0006083	acetate metabolic process(GO:0006083)
0.1	0.4	GO:0006538	glutamate catabolic process(GO:0006538)
0.1	2.6	GO:0006921	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1	0.3	GO:0035087	siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.1	0.4	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.1	0.3	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.1	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.1	0.3	GO:0002447	eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.1	0.3	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.3	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	0.2	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1	0.3	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1	0.1	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.1	0.3	GO:0003162	atrioventricular node development(GO:0003162)
0.1	0.3	GO:0060178	regulation of exocyst localization(GO:0060178)
0.1	0.3	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1	0.2	GO:1903416	response to glycoside(GO:1903416)
0.1	0.4	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1	0.6	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.1	0.5	GO:0061042	vascular wound healing(GO:0061042)
0.1	0.5	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.1	0.7	GO:0072102	glomerulus morphogenesis(GO:0072102)
0.1	0.5	GO:1902222	L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1	0.2	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1	0.2	GO:0006562	proline catabolic process(GO:0006562)
0.1	0.4	GO:0009642	response to light intensity(GO:0009642)
0.1	0.2	GO:0034421	post-translational protein acetylation(GO:0034421)
0.1	0.1	GO:0038086	VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.1	0.4	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.1	0.5	GO:0070995	NADPH oxidation(GO:0070995)
0.1	0.3	GO:0071877	regulation of adrenergic receptor signaling pathway(GO:0071877)
0.1	0.7	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1	0.3	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1	0.2	GO:0070949	regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.1	0.2	GO:0021699	cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.1	0.1	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1	0.3	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
0.1	0.1	GO:0061198	fungiform papilla formation(GO:0061198)
0.1	0.3	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.1	0.3	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.1	0.1	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1	0.1	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.1	0.5	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.1	0.1	GO:0071492	cellular response to UV-A(GO:0071492)
0.1	0.1	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.1	0.2	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.1	0.4	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.2	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	0.2	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1	0.3	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.1	0.6	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	0.1	GO:0021550	medulla oblongata development(GO:0021550)
0.1	0.1	GO:0002424	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.1	0.2	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1	0.2	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0	0.2	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.1	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.1	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
0.0	0.1	GO:0038171	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.1	GO:0000255	allantoin metabolic process(GO:0000255)
0.0	0.3	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.2	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	1.1	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.0	0.1	GO:0051795	positive regulation of catagen(GO:0051795)
0.0	0.1	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.1	GO:0034727	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0	0.6	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.1	GO:0000087	mitotic M phase(GO:0000087)
0.0	0.2	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.1	GO:0060535	trachea cartilage morphogenesis(GO:0060535)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:1902591	single-organism membrane budding(GO:1902591)
0.0	0.1	GO:0034197	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.7	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.1	GO:0061535	glutamate secretion, neurotransmission(GO:0061535)
0.0	0.1	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0	0.0	GO:0035513	oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0	0.2	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.8	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.3	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.1	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.1	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.2	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0	0.3	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.2	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.0	0.1	GO:0071280	cellular response to copper ion(GO:0071280)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	0.1	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.3	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.1	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0	0.1	GO:0006285	base-excision repair, AP site formation(GO:0006285)
0.0	0.1	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0	0.2	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.2	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.1	GO:0042851	L-alanine metabolic process(GO:0042851)
0.0	0.1	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0071462	cellular response to water stimulus(GO:0071462)
0.0	0.1	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0071798	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.2	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.1	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.1	GO:0071072	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) negative regulation of phospholipid biosynthetic process(GO:0071072) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0	0.0	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0	0.1	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.3	GO:2000781	positive regulation of double-strand break repair(GO:2000781)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.2	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.1	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.2	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.0	0.1	GO:0061668	mitochondrial ribosome assembly(GO:0061668)
0.0	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.0	0.1	GO:0010529	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0	0.1	GO:0046865	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0	0.1	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.1	GO:1900084	regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.3	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.0	0.1	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0	0.3	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.1	GO:0006382	adenosine to inosine editing(GO:0006382) base conversion or substitution editing(GO:0016553)
0.0	0.1	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.0	0.0	GO:2001025	positive regulation of response to drug(GO:2001025)
0.0	0.1	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.2	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.1	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:0090365	regulation of mRNA modification(GO:0090365)
0.0	0.1	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.1	GO:0051596	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.2	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.0	0.1	GO:0046878	positive regulation of saliva secretion(GO:0046878)
0.0	0.3	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.1	GO:0043974	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0	0.1	GO:0032252	secretory granule localization(GO:0032252)
0.0	0.1	GO:0010159	specification of organ position(GO:0010159)
0.0	0.1	GO:0097070	ductus arteriosus closure(GO:0097070)
0.0	0.1	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.0	0.2	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0	0.1	GO:0060591	chondroblast differentiation(GO:0060591)
0.0	0.2	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0	0.0	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.0	GO:0043133	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0	0.1	GO:0006742	NADP catabolic process(GO:0006742)
0.0	0.1	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.0	0.1	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.0	0.4	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.0	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0	0.1	GO:0019087	transformation of host cell by virus(GO:0019087)
0.0	0.1	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.6	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
0.0	0.0	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0	0.3	GO:0060252	positive regulation of glial cell proliferation(GO:0060252)
0.0	0.1	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.0	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
0.0	0.4	GO:0090036	regulation of protein kinase C signaling(GO:0090036)
0.0	0.0	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.0	0.1	GO:0060346	bone trabecula formation(GO:0060346)
0.0	0.0	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.0	0.2	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.5	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.0	0.1	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.0	0.3	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.3	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.1	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.0	0.0	GO:0019364	pyridine nucleotide catabolic process(GO:0019364)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.0	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.0	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.0	GO:0002901	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0	0.1	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.0	0.1	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.0	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
0.0	0.6	GO:0019432	triglyceride biosynthetic process(GO:0019432)
0.0	0.4	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.0	GO:0061316	canonical Wnt signaling pathway involved in heart development(GO:0061316)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.1	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.1	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.1	GO:0014894	response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0	0.1	GO:0009169	ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0044597	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.1	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.0	0.0	GO:0048769	sarcomerogenesis(GO:0048769)
0.0	0.2	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.0	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0	0.0	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0	0.1	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.0	0.0	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.0	0.0	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.1	GO:0014744	positive regulation of muscle adaptation(GO:0014744)
0.0	0.1	GO:0042505	tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
0.0	0.1	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
0.0	0.2	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0	0.0	GO:1905206	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0	0.1	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.1	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.1	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.0	0.2	GO:0070723	response to cholesterol(GO:0070723)
0.0	0.1	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.0	0.0	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.0	0.1	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0	0.1	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.1	GO:0002741	positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.0	0.0	GO:0043096	purine nucleobase salvage(GO:0043096)
0.0	0.1	GO:2001054	negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0	0.1	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0	0.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.1	GO:0003383	apical constriction(GO:0003383)
0.0	0.2	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.0	GO:0019896	axonal transport of mitochondrion(GO:0019896)
0.0	0.1	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	0.0	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.0	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.0	0.1	GO:0060283	negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0	0.0	GO:2000468	regulation of peroxidase activity(GO:2000468)
0.0	0.1	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.1	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0	0.1	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.0	GO:0052490	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0	0.0	GO:0032513	negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.0	0.0	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.1	GO:0019244	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
0.0	0.0	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.1	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.0	0.0	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.1	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.0	0.0	GO:0035973	aggrephagy(GO:0035973)
0.0	0.0	GO:0070268	cornification(GO:0070268)
0.0	0.0	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	0.1	GO:0043586	tongue development(GO:0043586)
0.0	0.1	GO:0045046	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0	0.0	GO:0034436	glycoprotein transport(GO:0034436)
0.0	0.1	GO:0060623	regulation of chromosome condensation(GO:0060623)
0.0	0.1	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.2	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.1	GO:1901339	regulation of store-operated calcium channel activity(GO:1901339)
0.0	0.0	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
0.0	0.1	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.1	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.1	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.1	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.1	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.1	GO:0042414	epinephrine metabolic process(GO:0042414)
0.0	0.0	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.1	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.1	GO:0035865	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0	0.0	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.2	GO:0035066	positive regulation of histone acetylation(GO:0035066)
0.0	0.6	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.0	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.0	0.0	GO:0090296	regulation of mitochondrial DNA replication(GO:0090296)
0.0	0.1	GO:0051873	disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0	0.1	GO:0051447	negative regulation of meiotic cell cycle(GO:0051447)
0.0	0.1	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.0	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.0	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0	0.1	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.1	GO:0015808	L-alanine transport(GO:0015808)
0.0	0.0	GO:0033686	positive regulation of luteinizing hormone secretion(GO:0033686)
0.0	0.0	GO:0072697	protein localization to cell cortex(GO:0072697)
0.0	0.0	GO:1903599	positive regulation of mitophagy(GO:1903599)
0.0	0.0	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.0	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.1	GO:0035826	rubidium ion transport(GO:0035826)
0.0	0.0	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.0	0.0	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
0.0	0.0	GO:0061010	gall bladder development(GO:0061010)
0.0	0.1	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.2	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.1	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.0	GO:0046083	adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.1	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.1	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.0	GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.0	0.1	GO:1904970	brush border assembly(GO:1904970)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.0	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.0	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.0	0.0	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.0	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.0	GO:0035483	gastric emptying(GO:0035483)
0.0	1.1	GO:0006633	fatty acid biosynthetic process(GO:0006633)
0.0	0.0	GO:1901857	positive regulation of cellular respiration(GO:1901857)
0.0	0.2	GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.0	0.1	GO:0044154	histone H3-K14 acetylation(GO:0044154)
0.0	0.2	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.0	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.1	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.0	0.0	GO:0031448	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0	0.0	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.0	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.2	GO:0007143	female meiotic division(GO:0007143)
0.0	0.0	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.0	0.0	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.0	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.3	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	0.0	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.0	GO:1901894	regulation of calcium-transporting ATPase activity(GO:1901894)
0.0	0.0	GO:0097475	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.0	0.0	GO:0043504	mitochondrial DNA repair(GO:0043504)
0.0	0.0	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.2	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	0.1	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.0	0.3	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:0033280	response to vitamin D(GO:0033280)
0.0	0.0	GO:0035627	ceramide transport(GO:0035627)
0.0	0.0	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.0	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.0	0.1	GO:0071361	cellular response to ethanol(GO:0071361)
0.0	0.0	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.0	0.0	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.0	GO:1900104	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0	0.1	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0	0.0	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0	0.0	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.0	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.0	0.0	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.0	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.0	GO:0070900	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0	0.0	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.4	GO:0048536	spleen development(GO:0048536)
0.0	0.0	GO:0034382	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.3	1.4	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2	0.5	GO:0097441	basilar dendrite(GO:0097441)
0.1	0.3	GO:1990635	proximal dendrite(GO:1990635)
0.1	0.8	GO:0042587	glycogen granule(GO:0042587)
0.1	0.3	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	0.3	GO:0005745	m-AAA complex(GO:0005745)
0.1	0.1	GO:0000125	PCAF complex(GO:0000125)
0.1	0.9	GO:0070852	cell body fiber(GO:0070852)
0.1	0.3	GO:0097149	centralspindlin complex(GO:0097149)
0.1	0.3	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1	0.3	GO:0071203	WASH complex(GO:0071203)
0.1	0.5	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1	0.3	GO:0044316	cone cell pedicle(GO:0044316)
0.1	0.3	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.1	0.3	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1	0.2	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1	0.3	GO:0097433	dense body(GO:0097433)
0.1	0.4	GO:0045180	basal cortex(GO:0045180)
0.1	0.3	GO:0031094	platelet dense tubular network(GO:0031094)
0.1	0.2	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.0	0.3	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
0.0	0.4	GO:0032300	mismatch repair complex(GO:0032300)
0.0	0.3	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.9	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.2	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.5	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.2	GO:0031415	NatA complex(GO:0031415)
0.0	0.4	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.2	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0	0.5	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.1	GO:0097543	ciliary inversin compartment(GO:0097543)
0.0	1.2	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.3	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.8	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.1	GO:0045293	mRNA editing complex(GO:0045293)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.3	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	0.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:1990357	terminal web(GO:1990357)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.1	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.4	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0071437	invadopodium(GO:0071437)
0.0	0.2	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	0.0	GO:0032280	symmetric synapse(GO:0032280)
0.0	0.3	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.2	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.2	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.2	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.7	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	1.0	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.9	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0036449	microtubule minus-end(GO:0036449)
0.0	0.1	GO:0043293	apoptosome(GO:0043293)
0.0	0.1	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.4	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.1	GO:0005610	laminin-5 complex(GO:0005610)
0.0	0.2	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.4	GO:0030686	90S preribosome(GO:0030686)
0.0	0.0	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.0	0.0	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.0	0.0	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.0	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.2	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.2	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.0	0.1	GO:0044292	dendrite terminus(GO:0044292)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.2	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0097546	ciliary base(GO:0097546)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.0	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.0	GO:0043511	inhibin complex(GO:0043511)
0.0	0.1	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.0	0.1	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.2	GO:0070069	cytochrome complex(GO:0070069)
0.0	0.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.0	GO:0005608	laminin-3 complex(GO:0005608)
0.0	0.0	GO:0002079	inner acrosomal membrane(GO:0002079)
0.0	0.2	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.0	GO:0034709	methylosome(GO:0034709)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.3	GO:0070538	oleic acid binding(GO:0070538)
0.3	0.8	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.3	0.8	GO:0004771	sterol esterase activity(GO:0004771)
0.3	0.8	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2	2.2	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.2	0.5	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2	0.5	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2	0.6	GO:0009374	biotin binding(GO:0009374)
0.2	0.5	GO:0055100	adiponectin binding(GO:0055100)
0.2	0.3	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.4	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.1	0.5	GO:0052833	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1	0.8	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	0.3	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.3	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	0.3	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1	0.3	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1	0.3	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.4	GO:0070546	L-phenylalanine aminotransferase activity(GO:0070546)
0.1	1.0	GO:0004312	fatty acid synthase activity(GO:0004312)
0.1	0.3	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1	0.8	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	0.8	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1	0.2	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.3	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.3	GO:1990239	steroid hormone binding(GO:1990239)
0.1	0.3	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.1	0.2	GO:0016649	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.3	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.1	0.2	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.1	0.5	GO:0034046	poly(G) binding(GO:0034046)
0.1	0.3	GO:0070191	methionine-R-sulfoxide reductase activity(GO:0070191)
0.1	0.2	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1	0.3	GO:0008199	ferric iron binding(GO:0008199)
0.1	0.5	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.1	0.2	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.6	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.2	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.0	0.3	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.2	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0015186	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.1	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.0	0.2	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0008412	4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.0	1.3	GO:0080032	prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.0	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.0	0.1	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.6	GO:0043274	phospholipase binding(GO:0043274)
0.0	1.4	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.4	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.4	GO:0048038	quinone binding(GO:0048038)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.2	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.6	GO:0008483	transaminase activity(GO:0008483)
0.0	0.3	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.3	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.2	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.2	GO:0070728	leucine binding(GO:0070728)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.2	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.1	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.0	0.1	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.6	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.0	GO:0035276	ethanol binding(GO:0035276)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.4	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.4	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	1.0	GO:0016749	N-succinyltransferase activity(GO:0016749)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.3	GO:0015250	water channel activity(GO:0015250)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.0	GO:0032557	pyrimidine ribonucleotide binding(GO:0032557)
0.0	0.3	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.1	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0	0.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.2	GO:0034211	GTP-dependent protein kinase activity(GO:0034211)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0	0.5	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.0	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.1	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.1	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.3	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.1	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.0	0.3	GO:0008796	bis(5'-nucleosyl)-tetraphosphatase activity(GO:0008796)
0.0	0.2	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.1	GO:1990405	protein antigen binding(GO:1990405)
0.0	0.1	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:1990932	5.8S rRNA binding(GO:1990932)
0.0	0.5	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.3	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.4	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.1	GO:0071253	connexin binding(GO:0071253)
0.0	0.1	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.2	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.1	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.2	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.2	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0	0.1	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0	0.1	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0035514	DNA demethylase activity(GO:0035514)
0.0	0.2	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	0.6	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.5	GO:0043738	N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0	0.1	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.2	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.1	GO:0031749	D2 dopamine receptor binding(GO:0031749)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.4	GO:0052712	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0	0.1	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.0	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.1	GO:0034916	4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.0	0.1	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.3	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.2	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.0	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0	0.3	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.6	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.0	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0	0.1	GO:0008297	single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0	0.1	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.0	GO:0051723	protein methylesterase activity(GO:0051723)
0.0	0.1	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.2	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.2	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.0	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.1	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.0	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.0	GO:0031433	telethonin binding(GO:0031433)
0.0	0.0	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.0	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.3	GO:0030507	spectrin binding(GO:0030507)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.3	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.0	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.3	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.0	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.4	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.3	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.0	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.0	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.0	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.0	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.0	0.2	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.2	GO:0045296	cadherin binding(GO:0045296)
0.0	0.0	GO:0035671	enone reductase activity(GO:0035671)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	1.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	1.2	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.3	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	2.1	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	1.1	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.8	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	1.1	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.8	PID FGF PATHWAY	FGF signaling pathway
0.0	0.2	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.2	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.9	PID P73PATHWAY	p73 transcription factor network
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.4	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.4	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.1	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.4	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.4	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.5	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.3	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.1	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.4	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	1.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	1.6	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.1	0.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	0.9	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	1.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	0.9	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	0.8	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.6	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.7	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.5	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	1.1	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.7	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.9	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.3	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.3	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	1.0	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.2	REACTOME SIGNALLING TO RAS	Genes involved in Signalling to RAS
0.0	0.6	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	1.2	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.7	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.6	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.0	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.1	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.7	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	0.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.3	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels

Results for Esrrg

Z-value: 2.39

Motif logo

Transcription factors associated with Esrrg

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Esrrg motif across conditions

Conditions sorted by the z-value of the Esrrg motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Esrrg

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: