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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Fli1

Z-value: 0.98

Motif logo

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Transcription factors associated with Fli1

Gene Symbol Gene ID Gene Info
Fli1
ENSMUSG00000016087.7 Friend leukemia integration 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr9_32541639_32541830Fli11390.9348090.711.2e-01Click!
chr9_32541322_32541500Fli11840.9138560.483.3e-01Click!
chr9_32540170_32540338Fli113410.3057130.414.2e-01Click!
chr9_32544785_32544960Fli120110.2241460.207.1e-01Click!

Activity of the Fli1 motif across conditions

Conditions sorted by the z-value of the Fli1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_106528042_106528212 0.88 Gm22711
 predicted gene, 22711
 26882
 0.13
chr8_111739071_111739223 0.73 Bcar1
 breast cancer anti-estrogen resistance 1
 4662
 0.21
chr1_157417899_157418197 0.70 2810025M15Rik
 RIKEN cDNA 2810025M15 gene
 1854
 0.24
chr2_154615306_154615471 0.66 4930519P11Rik
 RIKEN cDNA 4930519P11 gene
 1951
 0.18
chr10_80539568_80539827 0.57 Atp8b3
 ATPase, class I, type 8B, member 3
 573
 0.55
chr8_110672217_110672368 0.53 Vac14
 Vac14 homolog (S. cerevisiae)
 26712
 0.15
chr2_167254298_167254476 0.50 Ptgis
 prostaglandin I2 (prostacyclin) synthase
 13783
 0.14
chr14_31957201_31957408 0.49 D830044D21Rik
 RIKEN cDNA D830044D21 gene
 50776
 0.1
chr9_75039237_75039563 0.48 Arpp19
 cAMP-regulated phosphoprotein 19
 1483
 0.36
chr9_32761430_32761581 0.47 Gm27240
 predicted gene 27240
 50334
 0.11
chr6_115996644_115996808 0.45 Plxnd1
 plexin D1
 1721
 0.31
chr5_129701203_129701458 0.45 Septin14
 septin 14
 2929
 0.16
chr18_75483489_75483815 0.44 Gm10532
 predicted gene 10532
 30993
 0.21
chr11_98770698_98771034 0.43 Nr1d1
 nuclear receptor subfamily 1, group D, member 1
 440
 0.69
chr2_67711621_67711818 0.43 Gm13604
 predicted gene 13604
 3948
 0.2
chr5_99669989_99670358 0.43 Gm16226
 predicted gene 16226
 12237
 0.14
chr11_68898151_68898311 0.43 Rpl26
 ribosomal protein L26
 3352
 0.13
chr7_18927869_18928042 0.43 Nova2
 NOVA alternative splicing regulator 2
 2067
 0.18
chr2_4510286_4510488 0.42 Frmd4a
 FERM domain containing 4A
 37193
 0.15
chr10_120895362_120895561 0.42 Msrb3
 methionine sulfoxide reductase B3
 3640
 0.17
chr11_63377101_63377266 0.41 B130011K05Rik
 RIKEN cDNA B130011K05 gene
 35986
 0.18
chr6_31544399_31544550 0.41 Podxl
 podocalyxin-like
 19507
 0.17
chr5_107046594_107046884 0.40 Gm33474
 predicted gene, 33474
 2097
 0.34
chr18_34989351_34989609 0.40 Gm36037
 predicted gene, 36037
 6510
 0.15
chr5_143678512_143678672 0.40 Cyth3
 cytohesin 3
 27351
 0.14
chr17_24645080_24645260 0.37 Slc9a3r2
 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
 180
 0.85
chr2_102968533_102968684 0.36 Cd44
 CD44 antigen
 66943
 0.1
chr6_122826334_122826673 0.35 Foxj2
 forkhead box J2
 172
 0.9
chr11_19016500_19016765 0.35 Meis1
 Meis homeobox 1
 343
 0.83
chr8_105771287_105771438 0.35 Gfod2
 glucose-fructose oxidoreductase domain containing 2
 12698
 0.1
chr13_100543031_100543362 0.35 Ocln
 occludin
 9264
 0.12
chr1_178936614_178936788 0.34 Gm16564
 predicted gene 16564
 19087
 0.24
chr10_69925346_69925515 0.34 Ank3
 ankyrin 3, epithelial
 65
 0.99
chr8_84189691_84189963 0.34 Nanos3
 nanos C2HC-type zinc finger 3
 4610
 0.07
chr18_61953404_61953581 0.34 Sh3tc2
 SH3 domain and tetratricopeptide repeats 2
 408
 0.85
chr13_44067362_44067519 0.33 Gm33630
 predicted gene, 33630
 32520
 0.15
chr13_37510108_37510259 0.33 Gm29590
 predicted gene 29590
 465
 0.67
chr16_94580932_94581197 0.32 Dyrk1a
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
 10157
 0.19
chr17_26595433_26595607 0.32 Ergic1
 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
 644
 0.59
chr17_84037937_84038214 0.32 Gm49967
 predicted gene, 49967
 1185
 0.36
chr9_122084266_122084690 0.32 Snrk
 SNF related kinase
 32788
 0.08
chr2_92354348_92354505 0.31 Phf21a
 PHD finger protein 21A
 5515
 0.12
chr7_122404778_122404929 0.31 Gm44663
 predicted gene 44663
 2398
 0.23
chr17_4199793_4199983 0.31 4930548J01Rik
 RIKEN cDNA 4930548J01 gene
 77775
 0.11
chr1_138967552_138967703 0.31 Dennd1b
 DENN/MADD domain containing 1B
 93
 0.91
chr11_100392066_100392243 0.28 Jup
 junction plakoglobin
 5384
 0.08
chr3_122423925_122424117 0.28 Bcar3
 breast cancer anti-estrogen resistance 3
 4198
 0.18
chr7_84335830_84336210 0.28 Gm30873
 predicted gene, 30873
 2075
 0.28
chr1_107645210_107645382 0.28 Serpinb8
 serine (or cysteine) peptidase inhibitor, clade B, member 8
 39416
 0.15
chr3_148907132_148907314 0.28 Adgrl2
 adhesion G protein-coupled receptor L2
 47412
 0.16
chr6_83475613_83475764 0.28 Dguok
 deoxyguanosine kinase
 11322
 0.12
chr6_53070500_53070680 0.27 Jazf1
 JAZF zinc finger 1
 1959
 0.36
chr2_131134497_131134751 0.27 Gm11037
 predicted gene 11037
 1127
 0.32
chr16_20371861_20372035 0.27 Abcc5
 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
 4694
 0.18
chr11_16751759_16751915 0.26 Egfr
 epidermal growth factor receptor
 366
 0.88
chr2_72183135_72183304 0.26 Rapgef4
 Rap guanine nucleotide exchange factor (GEF) 4
 3526
 0.24
chr14_7819506_7819687 0.26 Flnb
 filamin, beta
 1639
 0.32
chr9_70244291_70244584 0.25 Myo1e
 myosin IE
 37069
 0.16
chr2_93223637_93223793 0.25 Tspan18
 tetraspanin 18
 4071
 0.26
chr4_106575149_106575301 0.25 Gm12744
 predicted gene 12744
 13883
 0.1
chr3_132479376_132479701 0.25 Gm42880
 predicted gene 42880
 33990
 0.19
chr16_95964505_95964671 0.24 Psmg1
 proteasome (prosome, macropain) assembly chaperone 1
 25310
 0.13
chr10_68842447_68842629 0.24 1700048P04Rik
 RIKEN cDNA 1700048P04 gene
 61962
 0.13
chr3_61185919_61186073 0.24 Gm37719
 predicted gene, 37719
 105450
 0.07
chr4_43406064_43406489 0.24 Rusc2
 RUN and SH3 domain containing 2
 159
 0.93
chr12_80226238_80226389 0.24 Gm47767
 predicted gene, 47767
 17070
 0.14
chr6_87389476_87389814 0.23 Gkn3
 gastrokine 3
 710
 0.57
chr10_118797429_118797609 0.23 Gm4065
 predicted gene 4065
 7740
 0.17
chr10_86689713_86689885 0.23 Gm15344
 predicted gene 15344
 3296
 0.09
chr7_28442822_28442993 0.22 Gmfg
 glia maturation factor, gamma
 200
 0.86
chr3_59229138_59229406 0.22 P2ry12
 purinergic receptor P2Y, G-protein coupled 12
 1691
 0.29
chr17_15373087_15373287 0.22 Dll1
 delta like canonical Notch ligand 1
 885
 0.54
chr9_43220553_43220704 0.22 Oaf
 out at first homolog
 3346
 0.18
chr1_134238279_134238430 0.22 Adora1
 adenosine A1 receptor
 2923
 0.2
chr2_144181951_144182219 0.21 Gm5535
 predicted gene 5535
 2999
 0.21
chr6_22004958_22005119 0.21 Cped1
 cadherin-like and PC-esterase domain containing 1
 12028
 0.25
chr1_39735925_39736349 0.21 Rfx8
 regulatory factor X 8
 15140
 0.19
chr7_28440830_28441020 0.21 Gmfg
 glia maturation factor, gamma
 2
 0.94
chr1_125435331_125435561 0.21 Actr3
 ARP3 actin-related protein 3
 8
 0.98
chr9_21291584_21291735 0.21 Cdkn2d
 cyclin dependent kinase inhibitor 2D
 252
 0.82
chr4_13833049_13833208 0.21 Runx1t1
 RUNX1 translocation partner 1
 48346
 0.18
chr8_126593928_126594215 0.21 Irf2bp2
 interferon regulatory factor 2 binding protein 2
 85
 0.98
chr4_136148351_136148658 0.20 Id3
 inhibitor of DNA binding 3
 3530
 0.17
chr10_81327977_81328184 0.20 Tbxa2r
 thromboxane A2 receptor
 651
 0.39
chr14_63247586_63247967 0.19 Gata4
 GATA binding protein 4
 2505
 0.26
chr5_122209998_122210149 0.19 Hvcn1
 hydrogen voltage-gated channel 1
 40
 0.96
chr11_100388061_100388239 0.19 Jup
 junction plakoglobin
 1380
 0.21
chr2_26493309_26493736 0.18 Notch1
 notch 1
 10300
 0.1
chr4_142084102_142084861 0.18 Tmem51os1
 Tmem51 opposite strand 1
 141
 0.54
chr14_121435885_121436040 0.18 Gm33299
 predicted gene, 33299
 19800
 0.17
chr5_150611809_150611960 0.18 Gm43597
 predicted gene 43597
 4881
 0.11
chr1_180330369_180330586 0.18 Itpkb
 inositol 1,4,5-trisphosphate 3-kinase B
 8
 0.54
chr17_15135586_15135747 0.18 Gm35455
 predicted gene, 35455
 16493
 0.18
chr4_47251829_47251990 0.18 Col15a1
 collagen, type XV, alpha 1
 6626
 0.22
chr4_122945793_122945944 0.18 Mfsd2a
 major facilitator superfamily domain containing 2A
 14122
 0.13
chr18_64369558_64369811 0.18 Onecut2
 one cut domain, family member 2
 29664
 0.13
chr5_134680232_134680567 0.17 Limk1
 LIM-domain containing, protein kinase
 2151
 0.21
chr4_81275942_81276093 0.17 Mpdz
 multiple PDZ domain protein
 8682
 0.29
chr11_120346748_120346946 0.17 Gm23419
 predicted gene, 23419
 28
 0.58
chr9_20760817_20761153 0.17 Olfm2
 olfactomedin 2
 14636
 0.13
chr17_47299700_47300022 0.17 Trerf1
 transcriptional regulating factor 1
 5792
 0.18
chr11_70179506_70179670 0.17 Clec10a
 C-type lectin domain family 10, member A
 10103
 0.08
chr11_120815283_120815743 0.17 Fasn
 fatty acid synthase
 58
 0.94
chr17_47567364_47567544 0.16 Ccnd3
 cyclin D3
 25982
 0.1
chr11_98794764_98794936 0.16 Msl1
 male specific lethal 1
 666
 0.52
chr15_22046405_22046937 0.16 Gm49187
 predicted gene, 49187
 88239
 0.1
chr5_53948666_53948853 0.16 Gm43266
 predicted gene 43266
 30315
 0.16
chr4_140673630_140673798 0.16 Gm13025
 predicted gene 13025
 6039
 0.14
chrX_9128548_9128703 0.16 Fthl17-ps3
 ferritin, heavy polypeptide-like 17, pseudogene 3
 5158
 0.13
chr18_35942087_35942447 0.16 Gm23882
 predicted gene, 23882
 10557
 0.12
chr11_108752151_108752318 0.16 Cep112
 centrosomal protein 112
 29
 0.98
chr15_35887277_35887437 0.15 Vps13b
 vacuolar protein sorting 13B
 15635
 0.16
chr1_100706996_100707453 0.15 Gm29334
 predicted gene 29334
 53424
 0.15
chr5_148789218_148789510 0.15 4930505K14Rik
 RIKEN cDNA 4930505K14 gene
 11401
 0.15
chr12_3888007_3888205 0.15 Dnmt3a
 DNA methyltransferase 3A
 2657
 0.24
chr1_55226495_55226826 0.15 Rftn2
 raftlin family member 2
 122
 0.77
chr6_38941118_38941304 0.15 Tbxas1
 thromboxane A synthase 1, platelet
 190
 0.95
chr15_67146103_67146362 0.15 St3gal1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 17209
 0.24
chr5_116024413_116024572 0.15 Prkab1
 protein kinase, AMP-activated, beta 1 non-catalytic subunit
 16
 0.96
chr10_99467611_99467809 0.15 Gm35035
 predicted gene, 35035
 7480
 0.16
chr13_73352022_73352179 0.15 Eprn
 ephemeron, early developmental lncRNA
 4716
 0.18
chr4_82507892_82508053 0.14 Gm11266
 predicted gene 11266
 44
 0.97
chr2_119304857_119305179 0.14 Vps18
 VPS18 CORVET/HOPS core subunit
 16231
 0.1
chr18_69660434_69660585 0.14 Tcf4
 transcription factor 4
 3842
 0.35
chr11_93988808_93989028 0.14 Spag9
 sperm associated antigen 9
 7173
 0.15
chr2_12197838_12198004 0.14 Itga8
 integrin alpha 8
 4609
 0.27
chr3_51301711_51301885 0.14 Gm37399
 predicted gene, 37399
 1105
 0.37
chr4_49536807_49537181 0.13 Aldob
 aldolase B, fructose-bisphosphate
 1872
 0.25
chr8_26078485_26078636 0.13 Hook3
 hook microtubule tethering protein 3
 817
 0.46
chr9_30906121_30906748 0.13 Adamts15
 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
 3223
 0.28
chr19_24017522_24017784 0.13 Gm50305
 predicted gene, 50305
 12873
 0.17
chr15_77745405_77745688 0.13 Gm49410
 predicted gene, 49410
 4785
 0.11
chr13_90896944_90897260 0.13 Atp6ap1l
 ATPase, H+ transporting, lysosomal accessory protein 1-like
 1722
 0.38
chr2_169724307_169724473 0.13 Tshz2
 teashirt zinc finger family member 2
 90714
 0.08
chr3_96545689_96545844 0.13 Gm15441
 predicted gene 15441
 12049
 0.07
chr2_128704813_128704964 0.12 Mertk
 MER proto-oncogene tyrosine kinase
 5932
 0.17
chr5_23890845_23891003 0.12 AC117663.1
 solute carrier family 40 (iron-regulated transporter), member 1 (Slc40a1), pseudogene
 14481
 0.11
chr16_4512630_4512833 0.12 Srl
 sarcalumenin
 10332
 0.16
chr2_170290505_170290775 0.12 Gm14270
 predicted gene 14270
 5605
 0.25
chr9_106371683_106372113 0.12 Dusp7
 dual specificity phosphatase 7
 1154
 0.36
chr4_108076318_108076469 0.12 Scp2
 sterol carrier protein 2, liver
 4974
 0.15
chr3_89397517_89397668 0.11 Gm15417
 predicted gene 15417
 1596
 0.15
chr11_16900094_16900245 0.11 Egfr
 epidermal growth factor receptor
 5016
 0.22
chr7_84604824_84604975 0.11 Fah
 fumarylacetoacetate hydrolase
 830
 0.56
chr11_119685579_119685767 0.11 Rptor
 regulatory associated protein of MTOR, complex 1
 29729
 0.15
chr4_108040471_108040896 0.11 Gm23354
 predicted gene, 23354
 1117
 0.39
chr7_98084571_98084774 0.11 Myo7a
 myosin VIIA
 47
 0.98
chr11_3535115_3535308 0.11 Gm11947
 predicted gene 11947
 973
 0.34
chr2_118763590_118763758 0.10 Ccdc9b
 coiled-coil domain containing 9B
 1013
 0.39
chr1_174921018_174921617 0.10 Grem2
 gremlin 2, DAN family BMP antagonist
 502
 0.88
chr11_5510779_5510930 0.10 Xbp1
 X-box binding protein 1
 9805
 0.13
chr15_6909753_6910113 0.10 Osmr
 oncostatin M receptor
 34964
 0.21
chr10_28106282_28106464 0.10 Ptprk
 protein tyrosine phosphatase, receptor type, K
 31363
 0.19
chr13_110967143_110967402 0.10 Gm48547
 predicted gene, 48547
 51549
 0.12
chr8_123705299_123705474 0.10 6030466F02Rik
 RIKEN cDNA 6030466F02 gene
 28572
 0.05
chr2_169996026_169996202 0.10 AY702102
 cDNA sequence AY702102
 32927
 0.22
chr6_115996180_115996399 0.10 Plxnd1
 plexin D1
 1284
 0.4
chr13_104617090_104617248 0.10 2610204G07Rik
 RIKEN cDNA 2610204G07 gene
 67762
 0.13
chr2_122256897_122257048 0.10 Sord
 sorbitol dehydrogenase
 22223
 0.09
chr2_144178364_144178517 0.10 Gm5535
 predicted gene 5535
 646
 0.67
chr4_148602442_148602607 0.10 Masp2
 mannan-binding lectin serine peptidase 2
 30
 0.95
chr16_31201119_31201450 0.10 Acap2
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
 39
 0.97
chr19_34745406_34745557 0.10 Slc16a12
 solute carrier family 16 (monocarboxylic acid transporters), member 12
 1808
 0.24
chr19_11517487_11517638 0.09 Gm19261
 predicted gene, 19261
 609
 0.45
chr6_82997803_82997973 0.09 Gm43981
 predicted gene, 43981
 6243
 0.08
chr7_27039864_27040232 0.09 Gm4290
 predicted gene 4290
 6846
 0.12
chr2_38287183_38287356 0.09 Dennd1a
 DENN/MADD domain containing 1A
 51
 0.96
chr16_11269926_11270104 0.09 Mir1945
 microRNA 1945
 15570
 0.12
chr6_37431530_37431865 0.09 Creb3l2
 cAMP responsive element binding protein 3-like 2
 10449
 0.27
chr18_68006220_68006482 0.09 Ldlrad4
 low density lipoprotein receptor class A domain containing 4
 73094
 0.09
chr12_15651775_15651933 0.09 Gm4804
 predicted gene 4804
 45442
 0.16
chr19_34841997_34842148 0.09 Mir107
 microRNA 107
 21299
 0.13
chr4_44065513_44065687 0.09 Gne
 glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
 1320
 0.35
chr5_90366149_90366302 0.09 Ankrd17
 ankyrin repeat domain 17
 3
 0.87
chr11_49196058_49196253 0.09 Zfp62
 zinc finger protein 62
 7137
 0.12
chr1_131096930_131097150 0.09 Mapkapk2
 MAP kinase-activated protein kinase 2
 786
 0.54
chr18_64643739_64644174 0.09 Atp8b1
 ATPase, class I, type 8B, member 1
 16851
 0.13
chr13_97297675_97297839 0.09 C430039J16Rik
 RIKEN cDNA C430039J16 gene
 14574
 0.18
chr16_15887069_15887635 0.09 Cebpd
 CCAAT/enhancer binding protein (C/EBP), delta
 66
 0.97
chr10_86992593_86993005 0.09 Gm16269
 predicted gene 16269
 7498
 0.16
chr2_128122505_128122660 0.09 Bcl2l11
 BCL2-like 11 (apoptosis facilitator)
 3456
 0.27
chr2_11331635_11331790 0.09 Gm37851
 predicted gene, 37851
 1113
 0.35
chr14_121073081_121073251 0.08 Farp1
 FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
 28913
 0.23
chr12_3874325_3874480 0.08 Dnmt3a
 DNA methyltransferase 3A
 8211
 0.17
chr2_28630005_28630405 0.08 Gfi1b
 growth factor independent 1B
 8223
 0.11
chrX_109095601_109095821 0.08 Sh3bgrl
 SH3-binding domain glutamic acid-rich protein like
 202
 0.94
chr9_40192823_40193002 0.08 Zfp202
 zinc finger protein 202
 583
 0.65
chr18_35296224_35296431 0.08 Sil1
 endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
 3488
 0.23
chr4_123667418_123667597 0.08 Gm12925
 predicted gene 12925
 53
 0.96
chr15_36879731_36879883 0.08 Gm10384
 predicted gene 10384
 9
 0.97
chr12_110510275_110510450 0.08 Gm19605
 predicted gene, 19605
 24154
 0.14
chr4_102571913_102572894 0.08 Pde4b
 phosphodiesterase 4B, cAMP specific
 2308
 0.44
chr1_86046974_86047152 0.08 2810459M11Rik
 RIKEN cDNA 2810459M11 gene
 1200
 0.33
chr4_133967208_133967543 0.08 Hmgn2
 high mobility group nucleosomal binding domain 2
 66
 0.96
chr2_58765113_58765779 0.08 Upp2
 uridine phosphorylase 2
 121
 0.97
chr7_30143897_30144083 0.08 Gm10988
 predicted gene 10988
 7851
 0.08
chr3_79519137_79519302 0.08 Fnip2
 folliculin interacting protein 2
 3967
 0.2
chr9_78230201_78230424 0.08 Gsta1
 glutathione S-transferase, alpha 1 (Ya)
 344
 0.77
chr3_98853787_98853964 0.08 Hsd3b1
 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
 5919
 0.11
chr17_46028764_46028966 0.07 Vegfa
 vascular endothelial growth factor A
 2491
 0.25

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Fli1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.1 0.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 0.3 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.1 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.3 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0060300 regulation of cytokine activity(GO:0060300)
0.0 0.1 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.3 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.2 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.1 GO:0046499 S-adenosylmethioninamine metabolic process(GO:0046499)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.0 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0003289 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.0 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.1 GO:0035728 response to hepatocyte growth factor(GO:0035728) cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.2 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.0 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.2 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.0 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.0 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.0 0.0 GO:0061625 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0 0.0 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 0.0 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.0 0.0 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.0 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.0 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.0 GO:0006701 progesterone biosynthetic process(GO:0006701)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.0 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0016443 bidentate ribonuclease III activity(GO:0016443)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor