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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Fli1

Z-value: 0.98

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Transcription factors associated with Fli1

Gene Symbol	Gene ID	Gene Info
Fli1 Ensembl NCBI MGI UniProt	ENSMUSG00000016087.7	Fli1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Fli1	chr9_32541639_32541830	139	0.934809	0.71	1.2e-01	Click!
Fli1	chr9_32541322_32541500	184	0.913856	0.48	3.3e-01	Click!
Fli1	chr9_32540170_32540338	1341	0.305713	0.41	4.2e-01	Click!
Fli1	chr9_32544785_32544960	2011	0.224146	0.20	7.1e-01	Click!

Activity of the Fli1 motif across conditions

Conditions sorted by the z-value of the Fli1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_106528042_106528212	0.88	Gm22711	predicted gene, 22711	26882	0.13
chr8_111739071_111739223	0.73	Bcar1	breast cancer anti-estrogen resistance 1	4662	0.21
chr1_157417899_157418197	0.70	2810025M15Rik	RIKEN cDNA 2810025M15 gene	1854	0.24
chr2_154615306_154615471	0.66	4930519P11Rik	RIKEN cDNA 4930519P11 gene	1951	0.18
chr10_80539568_80539827	0.57	Atp8b3	ATPase, class I, type 8B, member 3	573	0.55
chr8_110672217_110672368	0.53	Vac14	Vac14 homolog (S. cerevisiae)	26712	0.15
chr2_167254298_167254476	0.50	Ptgis	prostaglandin I2 (prostacyclin) synthase	13783	0.14
chr14_31957201_31957408	0.49	D830044D21Rik	RIKEN cDNA D830044D21 gene	50776	0.1
chr9_75039237_75039563	0.48	Arpp19	cAMP-regulated phosphoprotein 19	1483	0.36
chr9_32761430_32761581	0.47	Gm27240	predicted gene 27240	50334	0.11
chr6_115996644_115996808	0.45	Plxnd1	plexin D1	1721	0.31
chr5_129701203_129701458	0.45	Septin14	septin 14	2929	0.16
chr18_75483489_75483815	0.44	Gm10532	predicted gene 10532	30993	0.21
chr11_98770698_98771034	0.43	Nr1d1	nuclear receptor subfamily 1, group D, member 1	440	0.69
chr2_67711621_67711818	0.43	Gm13604	predicted gene 13604	3948	0.2
chr5_99669989_99670358	0.43	Gm16226	predicted gene 16226	12237	0.14
chr11_68898151_68898311	0.43	Rpl26	ribosomal protein L26	3352	0.13
chr7_18927869_18928042	0.43	Nova2	NOVA alternative splicing regulator 2	2067	0.18
chr2_4510286_4510488	0.42	Frmd4a	FERM domain containing 4A	37193	0.15
chr10_120895362_120895561	0.42	Msrb3	methionine sulfoxide reductase B3	3640	0.17
chr11_63377101_63377266	0.41	B130011K05Rik	RIKEN cDNA B130011K05 gene	35986	0.18
chr6_31544399_31544550	0.41	Podxl	podocalyxin-like	19507	0.17
chr5_107046594_107046884	0.40	Gm33474	predicted gene, 33474	2097	0.34
chr18_34989351_34989609	0.40	Gm36037	predicted gene, 36037	6510	0.15
chr5_143678512_143678672	0.40	Cyth3	cytohesin 3	27351	0.14
chr17_24645080_24645260	0.37	Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	180	0.85
chr2_102968533_102968684	0.36	Cd44	CD44 antigen	66943	0.1
chr6_122826334_122826673	0.35	Foxj2	forkhead box J2	172	0.9
chr11_19016500_19016765	0.35	Meis1	Meis homeobox 1	343	0.83
chr8_105771287_105771438	0.35	Gfod2	glucose-fructose oxidoreductase domain containing 2	12698	0.1
chr13_100543031_100543362	0.35	Ocln	occludin	9264	0.12
chr1_178936614_178936788	0.34	Gm16564	predicted gene 16564	19087	0.24
chr10_69925346_69925515	0.34	Ank3	ankyrin 3, epithelial	65	0.99
chr8_84189691_84189963	0.34	Nanos3	nanos C2HC-type zinc finger 3	4610	0.07
chr18_61953404_61953581	0.34	Sh3tc2	SH3 domain and tetratricopeptide repeats 2	408	0.85
chr13_44067362_44067519	0.33	Gm33630	predicted gene, 33630	32520	0.15
chr13_37510108_37510259	0.33	Gm29590	predicted gene 29590	465	0.67
chr16_94580932_94581197	0.32	Dyrk1a	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a	10157	0.19
chr17_26595433_26595607	0.32	Ergic1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	644	0.59
chr17_84037937_84038214	0.32	Gm49967	predicted gene, 49967	1185	0.36
chr9_122084266_122084690	0.32	Snrk	SNF related kinase	32788	0.08
chr2_92354348_92354505	0.31	Phf21a	PHD finger protein 21A	5515	0.12
chr7_122404778_122404929	0.31	Gm44663	predicted gene 44663	2398	0.23
chr17_4199793_4199983	0.31	4930548J01Rik	RIKEN cDNA 4930548J01 gene	77775	0.11
chr1_138967552_138967703	0.31	Dennd1b	DENN/MADD domain containing 1B	93	0.91
chr11_100392066_100392243	0.28	Jup	junction plakoglobin	5384	0.08
chr3_122423925_122424117	0.28	Bcar3	breast cancer anti-estrogen resistance 3	4198	0.18
chr7_84335830_84336210	0.28	Gm30873	predicted gene, 30873	2075	0.28
chr1_107645210_107645382	0.28	Serpinb8	serine (or cysteine) peptidase inhibitor, clade B, member 8	39416	0.15
chr3_148907132_148907314	0.28	Adgrl2	adhesion G protein-coupled receptor L2	47412	0.16
chr6_83475613_83475764	0.28	Dguok	deoxyguanosine kinase	11322	0.12
chr6_53070500_53070680	0.27	Jazf1	JAZF zinc finger 1	1959	0.36
chr2_131134497_131134751	0.27	Gm11037	predicted gene 11037	1127	0.32
chr16_20371861_20372035	0.27	Abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	4694	0.18
chr11_16751759_16751915	0.26	Egfr	epidermal growth factor receptor	366	0.88
chr2_72183135_72183304	0.26	Rapgef4	Rap guanine nucleotide exchange factor (GEF) 4	3526	0.24
chr14_7819506_7819687	0.26	Flnb	filamin, beta	1639	0.32
chr9_70244291_70244584	0.25	Myo1e	myosin IE	37069	0.16
chr2_93223637_93223793	0.25	Tspan18	tetraspanin 18	4071	0.26
chr4_106575149_106575301	0.25	Gm12744	predicted gene 12744	13883	0.1
chr3_132479376_132479701	0.25	Gm42880	predicted gene 42880	33990	0.19
chr16_95964505_95964671	0.24	Psmg1	proteasome (prosome, macropain) assembly chaperone 1	25310	0.13
chr10_68842447_68842629	0.24	1700048P04Rik	RIKEN cDNA 1700048P04 gene	61962	0.13
chr3_61185919_61186073	0.24	Gm37719	predicted gene, 37719	105450	0.07
chr4_43406064_43406489	0.24	Rusc2	RUN and SH3 domain containing 2	159	0.93
chr12_80226238_80226389	0.24	Gm47767	predicted gene, 47767	17070	0.14
chr6_87389476_87389814	0.23	Gkn3	gastrokine 3	710	0.57
chr10_118797429_118797609	0.23	Gm4065	predicted gene 4065	7740	0.17
chr10_86689713_86689885	0.23	Gm15344	predicted gene 15344	3296	0.09
chr7_28442822_28442993	0.22	Gmfg	glia maturation factor, gamma	200	0.86
chr3_59229138_59229406	0.22	P2ry12	purinergic receptor P2Y, G-protein coupled 12	1691	0.29
chr17_15373087_15373287	0.22	Dll1	delta like canonical Notch ligand 1	885	0.54
chr9_43220553_43220704	0.22	Oaf	out at first homolog	3346	0.18
chr1_134238279_134238430	0.22	Adora1	adenosine A1 receptor	2923	0.2
chr2_144181951_144182219	0.21	Gm5535	predicted gene 5535	2999	0.21
chr6_22004958_22005119	0.21	Cped1	cadherin-like and PC-esterase domain containing 1	12028	0.25
chr1_39735925_39736349	0.21	Rfx8	regulatory factor X 8	15140	0.19
chr7_28440830_28441020	0.21	Gmfg	glia maturation factor, gamma	2	0.94
chr1_125435331_125435561	0.21	Actr3	ARP3 actin-related protein 3	8	0.98
chr9_21291584_21291735	0.21	Cdkn2d	cyclin dependent kinase inhibitor 2D	252	0.82
chr4_13833049_13833208	0.21	Runx1t1	RUNX1 translocation partner 1	48346	0.18
chr8_126593928_126594215	0.21	Irf2bp2	interferon regulatory factor 2 binding protein 2	85	0.98
chr4_136148351_136148658	0.20	Id3	inhibitor of DNA binding 3	3530	0.17
chr10_81327977_81328184	0.20	Tbxa2r	thromboxane A2 receptor	651	0.39
chr14_63247586_63247967	0.19	Gata4	GATA binding protein 4	2505	0.26
chr5_122209998_122210149	0.19	Hvcn1	hydrogen voltage-gated channel 1	40	0.96
chr11_100388061_100388239	0.19	Jup	junction plakoglobin	1380	0.21
chr2_26493309_26493736	0.18	Notch1	notch 1	10300	0.1
chr4_142084102_142084861	0.18	Tmem51os1	Tmem51 opposite strand 1	141	0.54
chr14_121435885_121436040	0.18	Gm33299	predicted gene, 33299	19800	0.17
chr5_150611809_150611960	0.18	Gm43597	predicted gene 43597	4881	0.11
chr1_180330369_180330586	0.18	Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	8	0.54
chr17_15135586_15135747	0.18	Gm35455	predicted gene, 35455	16493	0.18
chr4_47251829_47251990	0.18	Col15a1	collagen, type XV, alpha 1	6626	0.22
chr4_122945793_122945944	0.18	Mfsd2a	major facilitator superfamily domain containing 2A	14122	0.13
chr18_64369558_64369811	0.18	Onecut2	one cut domain, family member 2	29664	0.13
chr5_134680232_134680567	0.17	Limk1	LIM-domain containing, protein kinase	2151	0.21
chr4_81275942_81276093	0.17	Mpdz	multiple PDZ domain protein	8682	0.29
chr11_120346748_120346946	0.17	Gm23419	predicted gene, 23419	28	0.58
chr9_20760817_20761153	0.17	Olfm2	olfactomedin 2	14636	0.13
chr17_47299700_47300022	0.17	Trerf1	transcriptional regulating factor 1	5792	0.18
chr11_70179506_70179670	0.17	Clec10a	C-type lectin domain family 10, member A	10103	0.08
chr11_120815283_120815743	0.17	Fasn	fatty acid synthase	58	0.94
chr17_47567364_47567544	0.16	Ccnd3	cyclin D3	25982	0.1
chr11_98794764_98794936	0.16	Msl1	male specific lethal 1	666	0.52
chr15_22046405_22046937	0.16	Gm49187	predicted gene, 49187	88239	0.1
chr5_53948666_53948853	0.16	Gm43266	predicted gene 43266	30315	0.16
chr4_140673630_140673798	0.16	Gm13025	predicted gene 13025	6039	0.14
chrX_9128548_9128703	0.16	Fthl17-ps3	ferritin, heavy polypeptide-like 17, pseudogene 3	5158	0.13
chr18_35942087_35942447	0.16	Gm23882	predicted gene, 23882	10557	0.12
chr11_108752151_108752318	0.16	Cep112	centrosomal protein 112	29	0.98
chr15_35887277_35887437	0.15	Vps13b	vacuolar protein sorting 13B	15635	0.16
chr1_100706996_100707453	0.15	Gm29334	predicted gene 29334	53424	0.15
chr5_148789218_148789510	0.15	4930505K14Rik	RIKEN cDNA 4930505K14 gene	11401	0.15
chr12_3888007_3888205	0.15	Dnmt3a	DNA methyltransferase 3A	2657	0.24
chr1_55226495_55226826	0.15	Rftn2	raftlin family member 2	122	0.77
chr6_38941118_38941304	0.15	Tbxas1	thromboxane A synthase 1, platelet	190	0.95
chr15_67146103_67146362	0.15	St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	17209	0.24
chr5_116024413_116024572	0.15	Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	16	0.96
chr10_99467611_99467809	0.15	Gm35035	predicted gene, 35035	7480	0.16
chr13_73352022_73352179	0.15	Eprn	ephemeron, early developmental lncRNA	4716	0.18
chr4_82507892_82508053	0.14	Gm11266	predicted gene 11266	44	0.97
chr2_119304857_119305179	0.14	Vps18	VPS18 CORVET/HOPS core subunit	16231	0.1
chr18_69660434_69660585	0.14	Tcf4	transcription factor 4	3842	0.35
chr11_93988808_93989028	0.14	Spag9	sperm associated antigen 9	7173	0.15
chr2_12197838_12198004	0.14	Itga8	integrin alpha 8	4609	0.27
chr3_51301711_51301885	0.14	Gm37399	predicted gene, 37399	1105	0.37
chr4_49536807_49537181	0.13	Aldob	aldolase B, fructose-bisphosphate	1872	0.25
chr8_26078485_26078636	0.13	Hook3	hook microtubule tethering protein 3	817	0.46
chr9_30906121_30906748	0.13	Adamts15	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15	3223	0.28
chr19_24017522_24017784	0.13	Gm50305	predicted gene, 50305	12873	0.17
chr15_77745405_77745688	0.13	Gm49410	predicted gene, 49410	4785	0.11
chr13_90896944_90897260	0.13	Atp6ap1l	ATPase, H+ transporting, lysosomal accessory protein 1-like	1722	0.38
chr2_169724307_169724473	0.13	Tshz2	teashirt zinc finger family member 2	90714	0.08
chr3_96545689_96545844	0.13	Gm15441	predicted gene 15441	12049	0.07
chr2_128704813_128704964	0.12	Mertk	MER proto-oncogene tyrosine kinase	5932	0.17
chr5_23890845_23891003	0.12	AC117663.1	solute carrier family 40 (iron-regulated transporter), member 1 (Slc40a1), pseudogene	14481	0.11
chr16_4512630_4512833	0.12	Srl	sarcalumenin	10332	0.16
chr2_170290505_170290775	0.12	Gm14270	predicted gene 14270	5605	0.25
chr9_106371683_106372113	0.12	Dusp7	dual specificity phosphatase 7	1154	0.36
chr4_108076318_108076469	0.12	Scp2	sterol carrier protein 2, liver	4974	0.15
chr3_89397517_89397668	0.11	Gm15417	predicted gene 15417	1596	0.15
chr11_16900094_16900245	0.11	Egfr	epidermal growth factor receptor	5016	0.22
chr7_84604824_84604975	0.11	Fah	fumarylacetoacetate hydrolase	830	0.56
chr11_119685579_119685767	0.11	Rptor	regulatory associated protein of MTOR, complex 1	29729	0.15
chr4_108040471_108040896	0.11	Gm23354	predicted gene, 23354	1117	0.39
chr7_98084571_98084774	0.11	Myo7a	myosin VIIA	47	0.98
chr11_3535115_3535308	0.11	Gm11947	predicted gene 11947	973	0.34
chr2_118763590_118763758	0.10	Ccdc9b	coiled-coil domain containing 9B	1013	0.39
chr1_174921018_174921617	0.10	Grem2	gremlin 2, DAN family BMP antagonist	502	0.88
chr11_5510779_5510930	0.10	Xbp1	X-box binding protein 1	9805	0.13
chr15_6909753_6910113	0.10	Osmr	oncostatin M receptor	34964	0.21
chr10_28106282_28106464	0.10	Ptprk	protein tyrosine phosphatase, receptor type, K	31363	0.19
chr13_110967143_110967402	0.10	Gm48547	predicted gene, 48547	51549	0.12
chr8_123705299_123705474	0.10	6030466F02Rik	RIKEN cDNA 6030466F02 gene	28572	0.05
chr2_169996026_169996202	0.10	AY702102	cDNA sequence AY702102	32927	0.22
chr6_115996180_115996399	0.10	Plxnd1	plexin D1	1284	0.4
chr13_104617090_104617248	0.10	2610204G07Rik	RIKEN cDNA 2610204G07 gene	67762	0.13
chr2_122256897_122257048	0.10	Sord	sorbitol dehydrogenase	22223	0.09
chr2_144178364_144178517	0.10	Gm5535	predicted gene 5535	646	0.67
chr4_148602442_148602607	0.10	Masp2	mannan-binding lectin serine peptidase 2	30	0.95
chr16_31201119_31201450	0.10	Acap2	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2	39	0.97
chr19_34745406_34745557	0.10	Slc16a12	solute carrier family 16 (monocarboxylic acid transporters), member 12	1808	0.24
chr19_11517487_11517638	0.09	Gm19261	predicted gene, 19261	609	0.45
chr6_82997803_82997973	0.09	Gm43981	predicted gene, 43981	6243	0.08
chr7_27039864_27040232	0.09	Gm4290	predicted gene 4290	6846	0.12
chr2_38287183_38287356	0.09	Dennd1a	DENN/MADD domain containing 1A	51	0.96
chr16_11269926_11270104	0.09	Mir1945	microRNA 1945	15570	0.12
chr6_37431530_37431865	0.09	Creb3l2	cAMP responsive element binding protein 3-like 2	10449	0.27
chr18_68006220_68006482	0.09	Ldlrad4	low density lipoprotein receptor class A domain containing 4	73094	0.09
chr12_15651775_15651933	0.09	Gm4804	predicted gene 4804	45442	0.16
chr19_34841997_34842148	0.09	Mir107	microRNA 107	21299	0.13
chr4_44065513_44065687	0.09	Gne	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase	1320	0.35
chr5_90366149_90366302	0.09	Ankrd17	ankyrin repeat domain 17	3	0.87
chr11_49196058_49196253	0.09	Zfp62	zinc finger protein 62	7137	0.12
chr1_131096930_131097150	0.09	Mapkapk2	MAP kinase-activated protein kinase 2	786	0.54
chr18_64643739_64644174	0.09	Atp8b1	ATPase, class I, type 8B, member 1	16851	0.13
chr13_97297675_97297839	0.09	C430039J16Rik	RIKEN cDNA C430039J16 gene	14574	0.18
chr16_15887069_15887635	0.09	Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	66	0.97
chr10_86992593_86993005	0.09	Gm16269	predicted gene 16269	7498	0.16
chr2_128122505_128122660	0.09	Bcl2l11	BCL2-like 11 (apoptosis facilitator)	3456	0.27
chr2_11331635_11331790	0.09	Gm37851	predicted gene, 37851	1113	0.35
chr14_121073081_121073251	0.08	Farp1	FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)	28913	0.23
chr12_3874325_3874480	0.08	Dnmt3a	DNA methyltransferase 3A	8211	0.17
chr2_28630005_28630405	0.08	Gfi1b	growth factor independent 1B	8223	0.11
chrX_109095601_109095821	0.08	Sh3bgrl	SH3-binding domain glutamic acid-rich protein like	202	0.94
chr9_40192823_40193002	0.08	Zfp202	zinc finger protein 202	583	0.65
chr18_35296224_35296431	0.08	Sil1	endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)	3488	0.23
chr4_123667418_123667597	0.08	Gm12925	predicted gene 12925	53	0.96
chr15_36879731_36879883	0.08	Gm10384	predicted gene 10384	9	0.97
chr12_110510275_110510450	0.08	Gm19605	predicted gene, 19605	24154	0.14
chr4_102571913_102572894	0.08	Pde4b	phosphodiesterase 4B, cAMP specific	2308	0.44
chr1_86046974_86047152	0.08	2810459M11Rik	RIKEN cDNA 2810459M11 gene	1200	0.33
chr4_133967208_133967543	0.08	Hmgn2	high mobility group nucleosomal binding domain 2	66	0.96
chr2_58765113_58765779	0.08	Upp2	uridine phosphorylase 2	121	0.97
chr7_30143897_30144083	0.08	Gm10988	predicted gene 10988	7851	0.08
chr3_79519137_79519302	0.08	Fnip2	folliculin interacting protein 2	3967	0.2
chr9_78230201_78230424	0.08	Gsta1	glutathione S-transferase, alpha 1 (Ya)	344	0.77
chr3_98853787_98853964	0.08	Hsd3b1	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	5919	0.11
chr17_46028764_46028966	0.07	Vegfa	vascular endothelial growth factor A	2491	0.25

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Fli1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.1	0.4	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1	0.3	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1	0.2	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.1	0.3	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.0	0.1	GO:0045608	negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0	0.2	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.3	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.0	0.1	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0	0.3	GO:0045332	phospholipid translocation(GO:0045332)
0.0	0.1	GO:0060300	regulation of cytokine activity(GO:0060300)
0.0	0.1	GO:0032596	protein transport into membrane raft(GO:0032596)
0.0	0.1	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.3	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.0	0.3	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.1	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.0	0.2	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.2	GO:0048102	autophagic cell death(GO:0048102)
0.0	0.1	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.0	0.1	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.1	GO:1904124	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0	0.0	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0003289	septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
0.0	0.3	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.0	0.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.0	0.1	GO:0002159	desmosome assembly(GO:0002159)
0.0	0.1	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.0	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:0035728	response to hepatocyte growth factor(GO:0035728) cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0	0.2	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.0	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0	0.0	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.2	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	0.0	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0	0.0	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.0	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.0	0.0	GO:0061625	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.0	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.0	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)
0.0	0.0	GO:0072310	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0	0.0	GO:1904395	regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0	0.0	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.0	0.0	GO:0006701	progesterone biosynthetic process(GO:0006701)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.3	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.3	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.2	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	0.0	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0048408	epidermal growth factor binding(GO:0048408)
0.0	0.4	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.2	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.4	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.1	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.3	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.0	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.2	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0016443	bidentate ribonuclease III activity(GO:0016443)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.4	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.0	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0036122	BMP binding(GO:0036122)
0.0	0.0	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0	0.1	GO:0070191	methionine-R-sulfoxide reductase activity(GO:0070191)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.3	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.3	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor