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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Fosb

Z-value: 1.49

Motif logo

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Transcription factors associated with Fosb

Gene Symbol Gene ID Gene Info
Fosb
ENSMUSG00000003545.2 FBJ osteosarcoma oncogene B

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_19320068_19320228Fosb100970.066494-0.853.4e-02Click!
chr7_19310289_19310447Fosb3170.728755-0.758.5e-02Click!
chr7_19316542_19316693Fosb65660.071981-0.749.1e-02Click!
chr7_19308580_19308766Fosb9270.303846-0.749.6e-02Click!
chr7_19309024_19309201Fosb4880.566308-0.691.3e-01Click!

Activity of the Fosb motif across conditions

Conditions sorted by the z-value of the Fosb motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr18_81319673_81319824 1.82 Gm30192
 predicted gene, 30192
 55040
 0.14
chr8_128648206_128648359 1.38 Gm26002
 predicted gene, 26002
 2715
 0.24
chr17_25127135_25127453 1.20 Clcn7
 chloride channel, voltage-sensitive 7
 6097
 0.1
chr8_128333459_128333621 1.15 Nrp1
 neuropilin 1
 25064
 0.19
chr11_16781411_16781603 1.12 Egfr
 epidermal growth factor receptor
 29277
 0.16
chr19_40153747_40153898 1.12 Cyp2c70
 cytochrome P450, family 2, subfamily c, polypeptide 70
 33464
 0.13
chr9_74947099_74947265 1.12 Fam214a
 family with sequence similarity 214, member A
 5702
 0.22
chr4_52815809_52815985 1.10 Olfr275
 olfactory receptor 275
 1293
 0.37
chr5_135693560_135693734 0.95 Por
 P450 (cytochrome) oxidoreductase
 4489
 0.12
chr15_96930772_96930923 0.88 Rpl10a-ps3
 ribosomal protein L10A, pseudogene 3
 7442
 0.28
chr17_64765537_64765696 0.84 Dreh
 down-regulated in hepatocellular carcinoma
 1495
 0.41
chr3_99188109_99188313 0.81 Gm18982
 predicted gene, 18982
 6930
 0.13
chrX_98051224_98051403 0.75 Gm14802
 predicted gene 14802
 10938
 0.3
chr9_44079482_44079643 0.73 Usp2
 ubiquitin specific peptidase 2
 5377
 0.08
chr1_178600841_178601326 0.70 Gm24405
 predicted gene, 24405
 35822
 0.18
chr4_6273243_6273469 0.65 Cyp7a1
 cytochrome P450, family 7, subfamily a, polypeptide 1
 2275
 0.3
chr15_3411405_3411556 0.63 Ghr
 growth hormone receptor
 60164
 0.13
chr10_87880054_87880205 0.62 Igf1os
 insulin-like growth factor 1, opposite strand
 16748
 0.19
chr5_135736099_135736335 0.62 Mir7034
 microRNA 7034
 328
 0.49
chr2_65267631_65267817 0.61 Gm13592
 predicted gene 13592
 9693
 0.17
chr10_111583961_111584156 0.61 4933440J02Rik
 RIKEN cDNA 4933440J02 gene
 10215
 0.16
chr13_31820560_31820717 0.60 Foxc1
 forkhead box C1
 14005
 0.16
chr8_126591993_126592171 0.59 Irf2bp2
 interferon regulatory factor 2 binding protein 2
 1904
 0.39
chr2_130819037_130819547 0.59 4930402H24Rik
 RIKEN cDNA 4930402H24 gene
 5000
 0.18
chr18_20971049_20971351 0.58 Rnf125
 ring finger protein 125
 9728
 0.2
chr1_60833760_60833934 0.57 Gm11581
 predicted gene 11581
 24731
 0.11
chr13_113168591_113168750 0.56 Gzmk
 granzyme K
 12227
 0.13
chr14_47983137_47983357 0.56 Gm49304
 predicted gene, 49304
 10556
 0.15
chr3_18210346_18210497 0.56 Gm23686
 predicted gene, 23686
 32796
 0.17
chr12_104089620_104089844 0.55 Serpina4-ps1
 serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1
 9083
 0.1
chr1_162815471_162815637 0.54 Fmo4
 flavin containing monooxygenase 4
 1582
 0.37
chr16_70331018_70331193 0.54 Gbe1
 glucan (1,4-alpha-), branching enzyme 1
 16971
 0.24
chr12_104109060_104109241 0.54 Gm23289
 predicted gene, 23289
 133
 0.92
chr1_193870865_193871025 0.54 Gm21362
 predicted gene, 21362
 3936
 0.37
chr3_116784094_116784363 0.50 Agl
 amylo-1,6-glucosidase, 4-alpha-glucanotransferase
 2478
 0.21
chr12_105728790_105728966 0.49 Ak7
 adenylate kinase 7
 10022
 0.17
chr11_59226278_59226466 0.49 Arf1
 ADP-ribosylation factor 1
 1790
 0.2
chr3_61217484_61217722 0.48 Gm37719
 predicted gene, 37719
 73843
 0.1
chr11_4190659_4190839 0.48 Tbc1d10a
 TBC1 domain family, member 10a
 3927
 0.12
chr11_16836119_16836554 0.48 Egfros
 epidermal growth factor receptor, opposite strand
 5634
 0.23
chr9_96823694_96824186 0.48 Gm8520
 predicted gene 8520
 9606
 0.15
chr19_26753091_26753242 0.47 Smarca2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
 434
 0.87
chr2_167325906_167326068 0.46 B4galt5
 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
 12087
 0.18
chr15_3413229_3413380 0.46 Ghr
 growth hormone receptor
 58340
 0.14
chr2_148018834_148018985 0.46 9030622O22Rik
 RIKEN cDNA 9030622O22 gene
 19361
 0.17
chrX_60462043_60462214 0.45 Gm7073
 predicted gene 7073
 5933
 0.23
chr11_106490027_106490381 0.45 Ern1
 endoplasmic reticulum (ER) to nucleus signalling 1
 2352
 0.23
chr1_45672893_45673066 0.45 Gm23216
 predicted gene, 23216
 12583
 0.19
chr2_126867909_126868096 0.45 Gm14212
 predicted gene 14212
 3499
 0.2
chr15_3514160_3514323 0.44 Ghr
 growth hormone receptor
 42597
 0.18
chr3_88717858_88718018 0.43 Rit1
 Ras-like without CAAX 1
 1027
 0.3
chr9_116194113_116194264 0.43 Gm4668
 predicted gene 4668
 5008
 0.18
chr2_132656980_132657153 0.43 Rpl23a-ps4
 ribosomal protein L23A, pseudogene 4
 5176
 0.13
chr1_91463744_91463928 0.43 Per2
 period circadian clock 2
 4512
 0.13
chr12_79501822_79502159 0.42 Rad51b
 RAD51 paralog B
 174637
 0.03
chr3_137511395_137511566 0.42 Gm4861
 predicted gene 4861
 41142
 0.16
chr18_35813778_35813929 0.42 Ube2d2a
 ubiquitin-conjugating enzyme E2D 2A
 12546
 0.09
chr13_35434169_35434335 0.42 Gm48703
 predicted gene, 48703
 38869
 0.17
chr5_138788893_138789272 0.41 Fam20c
 family with sequence similarity 20, member C
 308
 0.9
chr10_121457902_121458053 0.40 Rassf3
 Ras association (RalGDS/AF-6) domain family member 3
 4236
 0.14
chr7_98352590_98353259 0.40 Tsku
 tsukushi, small leucine rich proteoglycan
 7155
 0.18
chr16_93367939_93368144 0.40 1810044K17Rik
 RIKEN cDNA 1810044K17 gene
 198
 0.89
chr18_33335416_33335586 0.39 Gm5503
 predicted gene 5503
 49454
 0.16
chr1_70918439_70918607 0.39 Gm16236
 predicted gene 16236
 121507
 0.06
chr15_42674825_42675078 0.39 Gm17473
 predicted gene, 17473
 1290
 0.44
chr3_145995608_145995781 0.38 Syde2
 synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
 2023
 0.3
chr8_79710908_79711237 0.38 Abce1
 ATP-binding cassette, sub-family E (OABP), member 1
 578
 0.48
chr12_104850467_104850964 0.37 4930408O17Rik
 RIKEN cDNA 4930408O17 gene
 6656
 0.19
chr9_103507084_103507251 0.37 Tmem108
 transmembrane protein 108
 13556
 0.1
chr4_139601582_139602248 0.37 Gm21969
 predicted gene 21969
 1271
 0.37
chr1_85246945_85247096 0.36 Gm16028
 predicted gene 16028
 169
 0.83
chr1_137034426_137034730 0.36 Gm23763
 predicted gene, 23763
 44308
 0.16
chr17_10702814_10703005 0.36 Pacrg
 PARK2 co-regulated
 71842
 0.11
chr7_51868214_51868365 0.36 Gas2
 growth arrest specific 2
 4385
 0.17
chr14_89610572_89610930 0.36 Gm25415
 predicted gene, 25415
 96054
 0.09
chr18_8327970_8328137 0.35 Gm5500
 predicted pseudogene 5500
 87076
 0.09
chr15_58972603_58972890 0.35 Mtss1
 MTSS I-BAR domain containing 1
 207
 0.92
chr6_108313163_108313314 0.35 Itpr1
 inositol 1,4,5-trisphosphate receptor 1
 43016
 0.18
chr11_86629518_86629733 0.35 Gm11478
 predicted gene 11478
 1401
 0.38
chr2_142804438_142804612 0.35 Gm22310
 predicted gene, 22310
 17629
 0.25
chr4_108363811_108364169 0.34 Shisal2a
 shisa like 2A
 19359
 0.12
chr6_91712952_91713256 0.34 Gm44981
 predicted gene 44981
 174
 0.92
chr11_119777405_119777556 0.34 Rptor
 regulatory associated protein of MTOR, complex 1
 21293
 0.16
chr18_38406873_38407073 0.34 Ndfip1
 Nedd4 family interacting protein 1
 3423
 0.18
chr7_118104788_118104966 0.34 Rps15a
 ribosomal protein S15A
 10351
 0.17
chr1_67187795_67187968 0.33 Gm15668
 predicted gene 15668
 61319
 0.11
chr18_12686874_12687043 0.33 Ttc39c
 tetratricopeptide repeat domain 39C
 2770
 0.21
chr4_84131285_84131460 0.33 Gm12414
 predicted gene 12414
 1083
 0.59
chr18_53864446_53864629 0.32 Csnk1g3
 casein kinase 1, gamma 3
 2349
 0.42
chr1_10604540_10604691 0.32 Gm25253
 predicted gene, 25253
 48955
 0.13
chr15_58965948_58966356 0.32 Mtss1
 MTSS I-BAR domain containing 1
 6387
 0.16
chr2_85061178_85061331 0.31 Tnks1bp1
 tankyrase 1 binding protein 1
 290
 0.85
chr2_59997998_59998149 0.31 Gm13574
 predicted gene 13574
 5729
 0.19
chr5_140616803_140616967 0.31 Lfng
 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
 5200
 0.14
chr14_20291279_20291481 0.31 Nudt13
 nudix (nucleoside diphosphate linked moiety X)-type motif 13
 3317
 0.16
chr6_71420889_71421080 0.31 Gm44130
 predicted gene, 44130
 14123
 0.1
chr18_85490238_85490398 0.31 Gm7612
 predicted gene 7612
 226407
 0.02
chr14_17900415_17900617 0.31 Thrb
 thyroid hormone receptor beta
 62305
 0.13
chr12_79864462_79864614 0.30 9430078K24Rik
 RIKEN cDNA 9430078K24 gene
 60195
 0.12
chr4_117937047_117937475 0.30 Artn
 artemin
 7498
 0.12
chr14_74650101_74650379 0.30 Htr2a
 5-hydroxytryptamine (serotonin) receptor 2A
 9400
 0.24
chr2_18048778_18049088 0.30 Skida1
 SKI/DACH domain containing 1
 98
 0.94
chr17_23554288_23554546 0.30 Casp16
 caspase 16, apoptosis-related cysteine peptidase
 929
 0.34
chr2_74100092_74100243 0.30 A630050E04Rik
 RIKEN cDNA A630050E04 gene
 2175
 0.32
chr11_60240852_60241067 0.30 Gm12265
 predicted gene 12265
 149
 0.92
chr11_70972275_70972426 0.30 Rpain
 RPA interacting protein
 453
 0.66
chr19_14692311_14692469 0.30 Gm26026
 predicted gene, 26026
 26090
 0.21
chr19_27492565_27492719 0.30 Gm50101
 predicted gene, 50101
 19866
 0.23
chr8_80962240_80962391 0.29 Gm27048
 predicted gene, 27048
 23648
 0.15
chr14_31112566_31112718 0.29 Smim4
 small integral membrane protein 4
 16196
 0.1
chr6_136938692_136939081 0.29 Arhgdib
 Rho, GDP dissociation inhibitor (GDI) beta
 705
 0.59
chr19_8757228_8757608 0.29 Nxf1
 nuclear RNA export factor 1
 268
 0.68
chr2_130488707_130488873 0.28 9530056E24Rik
 RIKEN cDNA 9530056E24 gene
 35205
 0.08
chr7_137621172_137621473 0.28 Gm45683
 predicted gene 45683
 27767
 0.21
chr4_76424963_76425155 0.28 Ptprd
 protein tyrosine phosphatase, receptor type, D
 24921
 0.18
chr19_39282868_39283045 0.28 Cyp2c29
 cytochrome P450, family 2, subfamily c, polypeptide 29
 4118
 0.26
chr2_168524880_168525160 0.28 Nfatc2
 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
 27256
 0.2
chr7_39977983_39978150 0.28 Gm44992
 predicted gene 44992
 8
 0.98
chr19_15007147_15007306 0.27 Gm5513
 predicted pseudogene 5513
 46460
 0.21
chr8_61585158_61585376 0.27 Palld
 palladin, cytoskeletal associated protein
 5872
 0.3
chr2_129582332_129582507 0.27 Sirpa
 signal-regulatory protein alpha
 10416
 0.17
chr8_90870510_90870662 0.27 Gm45640
 predicted gene 45640
 5995
 0.14
chr2_31742282_31742433 0.27 Abl1
 c-abl oncogene 1, non-receptor tyrosine kinase
 17586
 0.14
chr16_91433633_91433806 0.27 Gm46562
 predicted gene, 46562
 24702
 0.08
chrX_10259432_10259607 0.26 Otc
 ornithine transcarbamylase
 7152
 0.26
chr11_98294355_98294506 0.26 Gm20644
 predicted gene 20644
 9048
 0.1
chr4_105557523_105557702 0.26 Gm12726
 predicted gene 12726
 20728
 0.24
chr6_87277564_87277945 0.26 Gm44418
 predicted gene, 44418
 9
 0.96
chr16_38289983_38290198 0.26 Nr1i2
 nuclear receptor subfamily 1, group I, member 2
 4734
 0.16
chr19_21820366_21820517 0.26 Gm50130
 predicted gene, 50130
 13315
 0.21
chr7_99173461_99173666 0.26 Dgat2
 diacylglycerol O-acyltransferase 2
 3457
 0.17
chr5_66035556_66035796 0.25 Rbm47
 RNA binding motif protein 47
 18876
 0.11
chr9_25504836_25504987 0.25 Eepd1
 endonuclease/exonuclease/phosphatase family domain containing 1
 22044
 0.17
chr8_124014864_124015025 0.25 Taf5l
 TATA-box binding protein associated factor 5 like
 5996
 0.11
chr8_56230092_56230281 0.25 Hpgd
 hydroxyprostaglandin dehydrogenase 15 (NAD)
 64399
 0.12
chr11_16914824_16915305 0.25 Egfr
 epidermal growth factor receptor
 9879
 0.18
chr6_84043664_84043821 0.25 Gm7498
 predicted gene 7498
 12154
 0.15
chr7_18948266_18948455 0.25 Nova2
 NOVA alternative splicing regulator 2
 22472
 0.08
chr10_66928213_66928377 0.25 Gm26576
 predicted gene, 26576
 7993
 0.17
chr1_58729553_58729738 0.25 Cflar
 CASP8 and FADD-like apoptosis regulator
 907
 0.49
chr16_59956556_59956707 0.25 Epha6
 Eph receptor A6
 49090
 0.18
chr15_84924832_84925200 0.25 Nup50
 nucleoporin 50
 1567
 0.26
chr11_16702482_16702935 0.25 Gm25698
 predicted gene, 25698
 30003
 0.15
chr4_108234244_108234395 0.24 Zyg11b
 zyg-ll family member B, cell cycle regulator
 7719
 0.16
chr11_101464329_101464518 0.24 Rnd2
 Rho family GTPase 2
 576
 0.46
chr2_32517571_32517751 0.24 Gm13412
 predicted gene 13412
 7370
 0.1
chr16_30375250_30375569 0.24 Atp13a3
 ATPase type 13A3
 13076
 0.2
chr13_101540438_101540589 0.24 Gm47533
 predicted gene, 47533
 4693
 0.19
chr9_68009384_68009551 0.24 Gm20745
 predicted gene, 20745
 16247
 0.23
chr19_42017962_42018130 0.24 Ubtd1
 ubiquitin domain containing 1
 897
 0.43
chr19_12633216_12633544 0.24 Glyat
 glycine-N-acyltransferase
 72
 0.94
chr5_21702946_21703133 0.24 Napepld
 N-acyl phosphatidylethanolamine phospholipase D
 1643
 0.28
chr15_58947619_58947948 0.24 Mtss1
 MTSS I-BAR domain containing 1
 5797
 0.14
chr16_77535131_77535288 0.24 Gm36963
 predicted gene, 36963
 4673
 0.14
chr16_20540431_20540616 0.24 Ap2m1
 adaptor-related protein complex 2, mu 1 subunit
 100
 0.9
chr3_149220840_149220991 0.24 Gm10287
 predicted gene 10287
 4830
 0.24
chr11_106410149_106410681 0.24 Icam2
 intercellular adhesion molecule 2
 22340
 0.13
chr16_55967011_55967191 0.24 Rpl24
 ribosomal protein L24
 554
 0.46
chr4_117126763_117126969 0.24 Tctex1d4
 Tctex1 domain containing 4
 53
 0.9
chr14_76715025_76715203 0.24 1700108F19Rik
 RIKEN cDNA 1700108F19 gene
 33360
 0.15
chr12_33369704_33369869 0.24 Atxn7l1
 ataxin 7-like 1
 2462
 0.24
chr5_88367022_88367405 0.24 Amtn
 amelotin
 8895
 0.17
chr1_35759768_35759937 0.24 Gm25634
 predicted gene, 25634
 1750
 0.42
chr4_140862219_140862586 0.24 4930515B02Rik
 RIKEN cDNA 4930515B02 gene
 10291
 0.12
chr14_89612108_89612276 0.23 Gm25415
 predicted gene, 25415
 94613
 0.09
chr19_40227668_40227819 0.23 Pdlim1
 PDZ and LIM domain 1 (elfin)
 3062
 0.2
chr1_4670727_4670906 0.23 Gm6085
 predicted gene 6085
 18587
 0.13
chr9_122856843_122857012 0.23 Zfp445
 zinc finger protein 445
 200
 0.89
chr6_121145100_121145251 0.23 Mical3
 microtubule associated monooxygenase, calponin and LIM domain containing 3
 14176
 0.14
chr15_59068526_59068830 0.23 Mtss1
 MTSS I-BAR domain containing 1
 13214
 0.22
chr4_106439943_106440414 0.23 Usp24
 ubiquitin specific peptidase 24
 11685
 0.15
chr3_27712516_27712706 0.23 Fndc3b
 fibronectin type III domain containing 3B
 1304
 0.58
chr15_62743599_62743898 0.23 Gm22521
 predicted gene, 22521
 49453
 0.17
chr10_80342748_80342921 0.23 Adamtsl5
 ADAMTS-like 5
 2404
 0.1
chr12_34664877_34665034 0.22 Gm47357
 predicted gene, 47357
 36317
 0.19
chr10_59884883_59885114 0.22 Dnajb12
 DnaJ heat shock protein family (Hsp40) member B12
 5372
 0.16
chr7_128529551_128529973 0.22 Bag3
 BCL2-associated athanogene 3
 6146
 0.12
chr14_47533422_47533895 0.22 Fbxo34
 F-box protein 34
 7579
 0.12
chr1_177188880_177189041 0.22 Gm37706
 predicted gene, 37706
 18098
 0.16
chr8_111246376_111246527 0.22 Glg1
 golgi apparatus protein 1
 12749
 0.16
chr11_12463629_12463800 0.22 Cobl
 cordon-bleu WH2 repeat
 1038
 0.69
chr9_65198022_65198189 0.22 Gm25313
 predicted gene, 25313
 1418
 0.27
chr8_64877797_64877973 0.22 Klhl2
 kelch-like 2, Mayven
 27868
 0.11
chr15_62337746_62337903 0.22 Pvt1
 Pvt1 oncogene
 115221
 0.06
chr2_27727019_27727170 0.22 Rxra
 retinoid X receptor alpha
 1875
 0.44
chr3_62458537_62458746 0.22 Dhx36
 DEAH (Asp-Glu-Ala-His) box polypeptide 36
 13946
 0.24
chr11_101111260_101111411 0.22 Retreg3
 reticulophagy regulator family member 3
 8430
 0.08
chr17_80772516_80772751 0.22 Map4k3
 mitogen-activated protein kinase kinase kinase kinase 3
 44148
 0.15
chr1_91445260_91445618 0.22 Per2
 period circadian clock 2
 4426
 0.13
chr11_120821685_120822756 0.22 Fasn
 fatty acid synthase
 1560
 0.22
chr10_81409520_81409671 0.22 Gm16104
 predicted gene 16104
 20
 0.92
chr8_72134846_72135406 0.22 Tpm4
 tropomyosin 4
 103
 0.92
chr4_108090689_108090857 0.21 Mir6397
 microRNA 6397
 3416
 0.18
chr16_43464306_43464503 0.21 Zbtb20
 zinc finger and BTB domain containing 20
 39210
 0.15
chr2_105252035_105252217 0.21 Them7
 thioesterase superfamily member 7
 27784
 0.2
chr16_35484667_35484833 0.21 Pdia5
 protein disulfide isomerase associated 5
 5839
 0.17
chr8_107293609_107293943 0.21 Nfat5
 nuclear factor of activated T cells 5
 217
 0.94
chr12_75545967_75546292 0.21 Ppp2r5e
 protein phosphatase 2, regulatory subunit B', epsilon
 3545
 0.25
chr6_108510231_108510410 0.21 Itpr1
 inositol 1,4,5-trisphosphate receptor 1
 2007
 0.27
chr3_52296364_52296605 0.21 Gm38034
 predicted gene, 38034
 14243
 0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Fosb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.4 GO:0071895 odontoblast differentiation(GO:0071895)
0.1 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.2 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.1 0.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0097212 lysosomal membrane organization(GO:0097212)
0.0 0.2 GO:0072338 creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.1 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.1 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.3 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.1 GO:1990314 cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.0 0.1 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.2 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.0 0.1 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0009838 abscission(GO:0009838)
0.0 0.1 GO:0060978 angiogenesis involved in coronary vascular morphogenesis(GO:0060978)
0.0 0.1 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.0 0.1 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.0 0.1 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.1 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.4 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.1 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:2000611 positive regulation of thyroid hormone generation(GO:2000611)
0.0 0.1 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:0007619 courtship behavior(GO:0007619)
0.0 0.1 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.2 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.0 0.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.1 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.0 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.0 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.0 GO:0042505 tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
0.0 0.0 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.0 0.0 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.0 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.0 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.0 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.0 0.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.0 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.0 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.2 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.0 GO:0030035 microspike assembly(GO:0030035)
0.0 0.0 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0042567 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.0 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.0 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)
0.0 0.0 GO:0097513 myosin II filament(GO:0097513)
0.0 0.0 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0032039 integrator complex(GO:0032039)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.2 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.0 0.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0 0.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.0 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.0 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.0 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0016443 bidentate ribonuclease III activity(GO:0016443)
0.0 0.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0001031 RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 0.6 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.0 REACTOME NEUROTRANSMITTER RECEPTOR BINDING AND DOWNSTREAM TRANSMISSION IN THE POSTSYNAPTIC CELL Genes involved in Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell