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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Foxd1

Z-value: 1.36

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Transcription factors associated with Foxd1

Gene Symbol	Gene ID	Gene Info
Foxd1 Ensembl NCBI MGI UniProt	ENSMUSG00000078302.3	Foxd1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Foxd1	chr13_98352948_98353139	1199	0.402992	0.88	2.2e-02	Click!

Activity of the Foxd1 motif across conditions

Conditions sorted by the z-value of the Foxd1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr4_117342819_117343008	0.89	Rnf220	ring finger protein 220	32544	0.12
chr10_8092375_8092549	0.87	Gm48614	predicted gene, 48614	71170	0.1
chr5_134941937_134942100	0.81	Mettl27	methyltransferase like 27	1556	0.18
chrX_105934496_105934654	0.62	Atrx	ATRX, chromatin remodeler	5172	0.21
chr12_82743501_82743658	0.59	Gm22149	predicted gene, 22149	28877	0.22
chr3_101881841_101882004	0.58	Slc22a15	solute carrier family 22 (organic anion/cation transporter), member 15	4035	0.26
chr19_32685579_32685730	0.57	Atad1	ATPase family, AAA domain containing 1	9216	0.24
chr19_32282556_32283119	0.56	Sgms1	sphingomyelin synthase 1	5873	0.26
chr13_77864889_77865040	0.54	Fam172a	family with sequence similarity 172, member A	156180	0.04
chr1_179833675_179833847	0.53	Ahctf1	AT hook containing transcription factor 1	30081	0.16
chr10_8086797_8087175	0.53	Gm48614	predicted gene, 48614	65694	0.11
chr12_62770911_62771078	0.53	Tspyl-ps	testis-specific protein, Y-encoded-like, pseudogene	66718	0.1
chr5_134550893_134551073	0.52	Gm42884	predicted gene 42884	1074	0.29
chr7_122665413_122665987	0.52	Cacng3	calcium channel, voltage-dependent, gamma subunit 3	4792	0.21
chr16_17217236_17217387	0.52	Rimbp3	RIMS binding protein 3	8708	0.09
chr11_57983626_57984029	0.52	Gm12249	predicted gene 12249	10693	0.15
chr16_22694632_22694783	0.52	Gm8118	predicted gene 8118	8513	0.18
chr13_60267432_60267612	0.51	Gm24999	predicted gene, 24999	26150	0.16
chr12_88472970_88473131	0.50	Gm48642	predicted gene, 48642	30718	0.1
chr15_25914259_25914426	0.49	Retreg1	reticulophagy regulator 1	3918	0.25
chr10_59537699_59537863	0.47	Gm10322	predicted gene 10322	78282	0.08
chr3_83996881_83997402	0.47	Tmem131l	transmembrane 131 like	28913	0.2
chr12_82353794_82353959	0.47	Sipa1l1	signal-induced proliferation-associated 1 like 1	11609	0.28
chr15_55819504_55819678	0.47	Sntb1	syntrophin, basic 1	86719	0.08
chr14_28652150_28652318	0.47	Gm35164	predicted gene, 35164	2475	0.38
chr10_37711570_37711751	0.46	Gm24710	predicted gene, 24710	220020	0.02
chr5_63893264_63893450	0.46	0610040J01Rik	RIKEN cDNA 0610040J01 gene	15881	0.17
chr10_122361947_122362104	0.46	Gm36041	predicted gene, 36041	24867	0.2
chr15_7088669_7089236	0.46	Lifr	LIF receptor alpha	1662	0.5
chr10_94568025_94568184	0.46	Tmcc3	transmembrane and coiled coil domains 3	7153	0.17
chr19_36627452_36627789	0.46	Hectd2os	Hectd2, opposite strand	1596	0.43
chr10_28524334_28524485	0.45	Ptprk	protein tyrosine phosphatase, receptor type, K	35742	0.22
chrX_106036704_106036855	0.45	Atp7a	ATPase, Cu++ transporting, alpha polypeptide	9457	0.17
chr4_41630291_41630458	0.44	Dnaic1	dynein, axonemal, intermediate chain 1	1270	0.29
chr18_60748821_60749236	0.44	Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	378	0.77
chr8_94678714_94678865	0.44	Pllp	plasma membrane proteolipid	183	0.91
chr8_11148911_11149083	0.44	Gm44717	predicted gene 44717	249	0.91
chr2_103870054_103870389	0.44	Gm13876	predicted gene 13876	18103	0.09
chr14_105603866_105604023	0.44	9330188P03Rik	RIKEN cDNA 9330188P03 gene	13887	0.16
chr15_67420967_67421299	0.44	1700012I11Rik	RIKEN cDNA 1700012I11 gene	194364	0.03
chrX_164035471_164035631	0.44	Car5b	carbonic anhydrase 5b, mitochondrial	7554	0.2
chr18_44610487_44610664	0.44	A930012L18Rik	RIKEN cDNA A930012L18 gene	51090	0.14
chr2_24742080_24742251	0.44	Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	20882	0.16
chr9_41306336_41306516	0.43	Mir100hg	Mir100 Mirlet7a-2 Mir125b-1 cluster host gene	20651	0.16
chr5_65096928_65097079	0.43	Tmem156	transmembrane protein 156	4871	0.18
chr1_86479051_86479408	0.43	Rpl30-ps6	ribosomal protein L30, pseudogene 6	5570	0.15
chr13_19306748_19306899	0.43	Trgc3	T cell receptor gamma, constant 3	45939	0.13
chr6_48857733_48857900	0.43	Gm7932	predicted gene 7932	2513	0.13
chr12_34406620_34406775	0.43	Hdac9	histone deacetylase 9	30610	0.24
chr2_84180208_84180377	0.43	Gm25972	predicted gene, 25972	30237	0.16
chr18_11858447_11858616	0.43	Cables1	CDK5 and Abl enzyme substrate 1	14231	0.16
chr1_167320339_167320493	0.43	Tmco1	transmembrane and coiled-coil domains 1	6279	0.12
chr18_46712101_46712569	0.42	Cdo1	cysteine dioxygenase 1, cytosolic	15694	0.12
chr1_133265093_133265439	0.42	Plekha6	pleckstrin homology domain containing, family A member 6	4190	0.17
chr15_96372725_96372895	0.42	Arid2	AT rich interactive domain 2 (ARID, RFX-like)	6004	0.21
chr6_87428535_87428790	0.42	Bmp10	bone morphogenetic protein 10	332	0.85
chr9_105878487_105878719	0.42	Col6a5	collagen, type VI, alpha 5	3203	0.27
chr6_111600197_111600355	0.42	Gm22093	predicted gene, 22093	2976	0.4
chr4_150825989_150826153	0.41	Gm13049	predicted gene 13049	338	0.86
chr16_78254868_78255025	0.41	E330011O21Rik	RIKEN cDNA E330011O21 gene	410	0.81
chr19_36629491_36629794	0.41	Hectd2os	Hectd2, opposite strand	3618	0.27
chr6_5496582_5496768	0.41	Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	366	0.92
chr8_4193425_4193618	0.40	Evi5l	ecotropic viral integration site 5 like	2229	0.17
chr11_3161350_3161520	0.40	Sfi1	Sfi1 homolog, spindle assembly associated (yeast)	3162	0.16
chr5_52360112_52360263	0.40	Sod3	superoxide dismutase 3, extracellular	3604	0.19
chr4_44994891_44995176	0.40	Grhpr	glyoxylate reductase/hydroxypyruvate reductase	13533	0.1
chr10_63413324_63413532	0.40	Gm7530	predicted gene 7530	429	0.77
chr6_126033747_126033913	0.40	Ntf3	neurotrophin 3	131130	0.05
chr10_95596327_95596490	0.40	Nudt4	nudix (nucleoside diphosphate linked moiety X)-type motif 4	32262	0.1
chr1_24693656_24693810	0.40	Lmbrd1	LMBR1 domain containing 1	14807	0.17
chr1_165609107_165609258	0.39	Mpzl1	myelin protein zero-like 1	364	0.78
chr11_82803141_82803324	0.39	Lig3	ligase III, DNA, ATP-dependent	4883	0.12
chr15_77891897_77892048	0.39	Txn2	thioredoxin 2	23728	0.13
chr5_104086712_104086871	0.39	Gm17660	predicted gene, 17660	9183	0.11
chr7_84201215_84201396	0.39	Gm44826	predicted gene 44826	9209	0.15
chr7_80402754_80402960	0.38	Furin	furin (paired basic amino acid cleaving enzyme)	95	0.93
chr4_155245715_155246079	0.38	Faap20	Fanconi anemia core complex associated protein 20	3905	0.19
chr16_33892287_33892604	0.38	Itgb5	integrin beta 5	498	0.81
chr14_27310963_27311149	0.38	Arhgef3	Rho guanine nucleotide exchange factor (GEF) 3	25010	0.19
chr3_65859331_65859533	0.38	Gm37131	predicted gene, 37131	5397	0.18
chr16_22439730_22439912	0.38	Etv5	ets variant 5	102	0.97
chr6_17513498_17513674	0.38	Met	met proto-oncogene	21415	0.21
chr2_152817536_152817750	0.38	Bcl2l1	BCL2-like 1	10892	0.12
chr10_116287055_116287225	0.38	Gm47625	predicted gene, 47625	2591	0.27
chr1_86447982_86448140	0.37	Tex44	testis expressed 44	21732	0.1
chr13_41321516_41321722	0.37	Nedd9	neural precursor cell expressed, developmentally down-regulated gene 9	37628	0.1
chr10_61327652_61327821	0.37	Pald1	phosphatase domain containing, paladin 1	14591	0.12
chr4_126113392_126113559	0.37	Stk40	serine/threonine kinase 40	4797	0.12
chr16_91146000_91146151	0.37	Gm49612	predicted gene, 49612	10599	0.1
chr17_86142116_86142294	0.37	Srbd1	S1 RNA binding domain 1	2970	0.28
chr5_46856306_46856720	0.37	Gm43092	predicted gene 43092	61833	0.16
chr2_72880103_72880418	0.37	Sp3	trans-acting transcription factor 3	60824	0.09
chr10_69930149_69930514	0.36	Ank3	ankyrin 3, epithelial	4198	0.35
chr12_113110325_113110520	0.36	Mta1	metastasis associated 1	12021	0.1
chr12_108304077_108304251	0.36	Hhipl1	hedgehog interacting protein-like 1	2106	0.27
chr19_4800564_4800742	0.36	Gm21844	predicted gene, 21844	859	0.32
chr18_38521952_38522103	0.36	Gm50349	predicted gene, 50349	40724	0.12
chr14_54434127_54434453	0.36	Mmp14	matrix metallopeptidase 14 (membrane-inserted)	1854	0.16
chr7_134497342_134497526	0.36	D7Ertd443e	DNA segment, Chr 7, ERATO Doi 443, expressed	1550	0.55
chr12_21166146_21166319	0.35	Asap2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	54278	0.1
chr15_97590730_97591033	0.35	Gm49506	predicted gene, 49506	32591	0.19
chr1_75521864_75522062	0.35	Stk11ip	serine/threonine kinase 11 interacting protein	152	0.9
chr9_119342839_119343002	0.35	Acaa1a	acetyl-Coenzyme A acyltransferase 1A	147	0.91
chr10_62795188_62795339	0.35	Ccar1	cell division cycle and apoptosis regulator 1	2977	0.15
chr10_127653471_127653627	0.35	Stat6	signal transducer and activator of transcription 6	470	0.63
chr16_35949490_35949675	0.35	Parp9	poly (ADP-ribose) polymerase family, member 9	1298	0.3
chr8_84740975_84741146	0.35	G430095P16Rik	RIKEN cDNA G430095P16 gene	18053	0.1
chr6_97971154_97971321	0.35	Mitf	melanogenesis associated transcription factor	20555	0.25
chr15_66911047_66911248	0.35	Ccn4	cellular communication network factor 4	1836	0.32
chr9_48592438_48592815	0.35	Nnmt	nicotinamide N-methyltransferase	4749	0.26
chr15_59391938_59392317	0.35	Nsmce2	NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase	17840	0.18
chr10_11150027_11150209	0.35	Shprh	SNF2 histone linker PHD RING helicase	594	0.78
chr1_165849593_165849764	0.35	Gm37469	predicted gene, 37469	634	0.54
chr4_117852028_117852199	0.35	Slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	2743	0.15
chr7_138867340_138867520	0.34	Ppp2r2d	protein phosphatase 2, regulatory subunit B, delta	980	0.43
chr14_46017259_46017572	0.34	Gm6580	predicted gene 6580	10013	0.17
chr10_8228115_8228580	0.34	Gm30906	predicted gene, 30906	52216	0.15
chr11_44155690_44155841	0.34	Gm12154	predicted gene 12154	111444	0.06
chrX_112984511_112984736	0.34	Gm14938	predicted gene 14938	17534	0.15
chrX_129949506_129949684	0.34	Diaph2	diaphanous related formin 2	22938	0.28
chr8_10904045_10904209	0.34	Gm2814	predicted gene 2814	3569	0.12
chr6_145767466_145768203	0.34	Rassf8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8	17263	0.18
chr5_3488489_3488661	0.34	Gm17590	predicted gene, 17590	7702	0.13
chr5_113204337_113204488	0.33	2900026A02Rik	RIKEN cDNA 2900026A02 gene	16824	0.12
chr7_67951889_67952040	0.33	Igf1r	insulin-like growth factor I receptor	863	0.66
chr5_114796772_114796944	0.33	Ankrd13a	ankyrin repeat domain 13a	1115	0.31
chr6_35253418_35253775	0.33	1810058I24Rik	RIKEN cDNA 1810058I24 gene	864	0.54
chr8_121580222_121580383	0.33	Gm17786	predicted gene, 17786	1463	0.23
chr2_27215557_27215850	0.33	Sardh	sarcosine dehydrogenase	71	0.96
chr16_18430516_18430667	0.33	Txnrd2	thioredoxin reductase 2	1666	0.22
chr3_122565390_122565553	0.33	Gm43569	predicted gene 43569	421	0.72
chr15_67423761_67424241	0.33	1700012I11Rik	RIKEN cDNA 1700012I11 gene	197232	0.03
chr10_24087275_24087474	0.33	Taar8b	trace amine-associated receptor 8B	4920	0.1
chr5_66798803_66798961	0.33	Limch1	LIM and calponin homology domains 1	52993	0.11
chr14_35146195_35146544	0.33	Gm49034	predicted gene, 49034	73069	0.12
chr11_94365374_94365707	0.33	Abcc3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	2383	0.24
chr12_76271569_76271743	0.33	Gm47526	predicted gene, 47526	6060	0.12
chr6_16701972_16702148	0.33	Gm36669	predicted gene, 36669	75464	0.11
chr3_122417274_122417702	0.33	Bcar3	breast cancer anti-estrogen resistance 3	2269	0.24
chr12_79140897_79141048	0.33	Arg2	arginase type II	10195	0.09
chr9_57281733_57281969	0.33	1700017B05Rik	RIKEN cDNA 1700017B05 gene	19239	0.14
chr17_50468359_50468519	0.32	Plcl2	phospholipase C-like 2	40964	0.19
chr11_50622338_50622503	0.32	Gm12198	predicted gene 12198	19972	0.17
chr9_61151961_61152206	0.32	I730028E13Rik	RIKEN cDNA I730028E13 gene	13568	0.15
chr4_130116362_130116530	0.32	Pef1	penta-EF hand domain containing 1	8890	0.14
chr18_70611236_70611413	0.32	Mbd2	methyl-CpG binding domain protein 2	6449	0.21
chr5_146967227_146967378	0.32	Mtif3	mitochondrial translational initiation factor 3	3502	0.21
chr13_34301223_34301392	0.32	Gm47086	predicted gene, 47086	17501	0.18
chrX_42112143_42112724	0.32	Gm14615	predicted gene 14615	18290	0.16
chr9_43561805_43561964	0.32	Gm36855	predicted gene, 36855	40880	0.13
chr4_86777161_86777312	0.32	Dennd4c	DENN/MADD domain containing 4C	607	0.77
chr1_39105614_39105798	0.32	Gm37091	predicted gene, 37091	22368	0.17
chr16_30603170_30603355	0.32	Fam43a	family with sequence similarity 43, member A	3539	0.24
chr10_41636277_41636445	0.32	Ccdc162	coiled-coil domain containing 162	23524	0.13
chr13_120025614_120025791	0.32	Gm36079	predicted gene, 36079	1309	0.25
chr15_6709205_6709602	0.32	Rictor	RPTOR independent companion of MTOR, complex 2	1020	0.58
chr5_22255477_22255648	0.32	Gm16113	predicted gene 16113	26020	0.16
chr12_76009151_76009311	0.32	Syne2	spectrin repeat containing, nuclear envelope 2	13069	0.25
chr5_148684126_148684386	0.31	Gm36186	predicted gene, 36186	27210	0.15
chr2_25363590_25363748	0.31	Uap1l1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1	29	0.93
chr3_108083014_108083206	0.31	Ampd2	adenosine monophosphate deaminase 2	2285	0.13
chr12_71719042_71719430	0.31	Gm47555	predicted gene, 47555	35149	0.17
chr1_157073744_157073917	0.31	Gm28694	predicted gene 28694	19796	0.15
chr15_89377307_89377495	0.31	Tymp	thymidine phosphorylase	362	0.6
chr11_78418219_78418374	0.31	Slc13a2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	3921	0.12
chr4_33262151_33262376	0.31	Pnrc1	proline-rich nuclear receptor coactivator 1	13753	0.16
chr11_7198754_7198905	0.31	Igfbp1	insulin-like growth factor binding protein 1	1047	0.5
chr13_35023472_35023629	0.31	Eci2	enoyl-Coenzyme A delta isomerase 2	3544	0.15
chr6_5517592_5517751	0.31	Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	21362	0.26
chr7_132931708_132932726	0.30	1500002F19Rik	RIKEN cDNA 1500002F19 gene	1020	0.34
chr4_123108028_123108191	0.30	Bmp8b	bone morphogenetic protein 8b	2944	0.16
chr10_12278119_12278297	0.30	Gm48723	predicted gene, 48723	46453	0.13
chr5_145880032_145880197	0.30	Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	150	0.95
chrX_165191272_165191423	0.30	Glra2	glycine receptor, alpha 2 subunit	136046	0.05
chr19_45445850_45446001	0.30	Btrc	beta-transducin repeat containing protein	417	0.83
chr8_109993075_109993269	0.30	Tat	tyrosine aminotransferase	2666	0.18
chr5_147894276_147894456	0.30	Slc46a3	solute carrier family 46, member 3	449	0.8
chr5_115167416_115167584	0.30	Mlec	malectin	9321	0.1
chr10_118581468_118581731	0.30	Ifngas1	Ifng antisense RNA 1	25074	0.2
chr10_96646651_96646843	0.30	Btg1	BTG anti-proliferation factor 1	29193	0.17
chr11_117970308_117970484	0.30	Socs3	suppressor of cytokine signaling 3	349	0.83
chr2_164445108_164445423	0.30	Sdc4	syndecan 4	1378	0.23
chr7_70788098_70788301	0.30	Gm24880	predicted gene, 24880	35783	0.18
chr10_68444703_68445037	0.30	Cabcoco1	ciliary associated calcium binding coiled-coil 1	80897	0.09
chr12_113252720_113252871	0.30	Gm25622	predicted gene, 25622	38646	0.1
chr15_66073884_66074203	0.30	Gm27153	predicted gene 27153	509	0.83
chr2_156763206_156763372	0.30	Dlgap4	DLG associated protein 4	3344	0.16
chr9_35134057_35134256	0.29	Gm24262	predicted gene, 24262	10480	0.12
chr2_50625473_50625690	0.29	Gm13484	predicted gene 13484	32486	0.2
chrX_100447058_100447240	0.29	Awat2	acyl-CoA wax alcohol acyltransferase 2	4432	0.18
chr17_12975251_12975429	0.29	Wtap	Wilms tumour 1-associating protein	8133	0.09
chr5_63936466_63936784	0.29	Rell1	RELT-like 1	5711	0.18
chr8_114541036_114541418	0.29	Gm16116	predicted gene 16116	53673	0.14
chr19_29268750_29269067	0.29	Jak2	Janus kinase 2	16467	0.17
chr13_115014976_115015141	0.29	Gm10734	predicted gene 10734	74443	0.07
chr12_110020945_110021120	0.29	Gm34667	predicted gene, 34667	2841	0.19
chr7_112497046_112497197	0.29	Parva	parvin, alpha	22580	0.2
chr14_121315574_121315760	0.29	Stk24	serine/threonine kinase 24	12192	0.21
chr1_184330776_184331172	0.29	Gm37223	predicted gene, 37223	27355	0.2
chr5_118291975_118292126	0.29	Gm25076	predicted gene, 25076	25601	0.16

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxd1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1	0.5	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1	0.3	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.1	0.3	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.1	0.2	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.1	0.4	GO:0042078	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1	0.4	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.1	0.2	GO:1902065	response to L-glutamate(GO:1902065)
0.1	0.2	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1	0.3	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.3	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.1	0.2	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1	0.2	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1	0.2	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	0.2	GO:0097503	sialylation(GO:0097503)
0.1	0.2	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.1	0.2	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.2	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.1	0.2	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1	0.3	GO:0006477	protein sulfation(GO:0006477)
0.1	0.2	GO:0052490	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0	0.1	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.2	GO:2000561	regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561)
0.0	0.1	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.1	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0	0.1	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.3	GO:0071073	positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0	0.3	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0000189	MAPK import into nucleus(GO:0000189)
0.0	0.3	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.2	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.2	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0	0.1	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.1	GO:2000599	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.0	0.1	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0	0.1	GO:0072050	S-shaped body morphogenesis(GO:0072050)
0.0	0.2	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0	0.2	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.1	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0	0.1	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.2	GO:0099515	actin filament-based transport(GO:0099515)
0.0	0.2	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.1	GO:0035523	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	0.2	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.3	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0042851	L-alanine metabolic process(GO:0042851)
0.0	0.1	GO:0072338	creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.1	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.0	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.0	0.1	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.0	0.1	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.0	0.1	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.1	GO:0009093	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0	0.1	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.1	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:1902031	regulation of NADP metabolic process(GO:1902031)
0.0	0.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.0	GO:0003097	renal water transport(GO:0003097)
0.0	0.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0	0.4	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
0.0	0.2	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.1	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.1	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.2	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
0.0	0.1	GO:0071635	negative regulation of transforming growth factor beta production(GO:0071635)
0.0	0.1	GO:0010159	specification of organ position(GO:0010159)
0.0	0.1	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.1	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.1	GO:1903551	regulation of extracellular exosome assembly(GO:1903551)
0.0	0.1	GO:0015817	histidine transport(GO:0015817)
0.0	0.1	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.1	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.0	0.1	GO:0032348	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.1	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.0	0.0	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.1	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0	0.1	GO:2000553	positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.0	0.1	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0	0.0	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0	0.1	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.1	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.1	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.1	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0	0.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.1	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.0	0.0	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.0	0.1	GO:0010911	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0	0.2	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.1	GO:0034182	regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
0.0	0.2	GO:0000059	protein import into nucleus, docking(GO:0000059)
0.0	0.1	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0	0.3	GO:0035278	miRNA mediated inhibition of translation(GO:0035278)
0.0	0.0	GO:2000698	positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698)
0.0	0.1	GO:0060486	Clara cell differentiation(GO:0060486)
0.0	0.0	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.0	0.1	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.1	GO:1903054	negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.0	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.2	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.0	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.0	0.1	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.0	0.1	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.1	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.0	GO:0045914	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.0	0.2	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.1	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.2	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0061055	myotome development(GO:0061055)
0.0	0.1	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.1	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.0	0.0	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.1	GO:0032847	regulation of cellular pH reduction(GO:0032847)
0.0	0.0	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.0	0.2	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.0	0.1	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0	0.0	GO:0043974	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0	0.0	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.1	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
0.0	0.0	GO:0010166	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0	0.0	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.1	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.0	GO:0003213	cardiac right atrium morphogenesis(GO:0003213)
0.0	0.1	GO:0043173	nucleotide salvage(GO:0043173)
0.0	0.1	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.2	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.2	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:1903596	regulation of gap junction assembly(GO:1903596) positive regulation of gap junction assembly(GO:1903598)
0.0	0.2	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.0	GO:0014735	regulation of muscle atrophy(GO:0014735)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.1	GO:0060437	lung growth(GO:0060437)
0.0	0.1	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.0	0.1	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.0	0.0	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0	0.0	GO:1902512	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0	0.1	GO:0009992	cellular water homeostasis(GO:0009992)
0.0	0.1	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.1	GO:0046689	response to mercury ion(GO:0046689)
0.0	0.0	GO:0071280	cellular response to copper ion(GO:0071280)
0.0	0.0	GO:0030070	insulin processing(GO:0030070)
0.0	0.1	GO:2000391	regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.0	0.4	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.1	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.1	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.1	GO:0036233	glycine import(GO:0036233)
0.0	0.0	GO:0036258	multivesicular body assembly(GO:0036258)
0.0	0.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.0	GO:0070671	response to interleukin-12(GO:0070671)
0.0	0.1	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.0	0.0	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.0	0.0	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.0	0.1	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.0	0.1	GO:0046110	xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
0.0	0.0	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.0	GO:0060066	oviduct development(GO:0060066)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.0	GO:0016237	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0	0.0	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0	0.0	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
0.0	0.1	GO:0036158	outer dynein arm assembly(GO:0036158)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.0	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0	0.0	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.0	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.0	0.0	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0	0.0	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	0.0	GO:0071677	positive regulation of mononuclear cell migration(GO:0071677)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.0	0.0	GO:2000384	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0	0.1	GO:0032986	nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:0044068	modulation by symbiont of host cellular process(GO:0044068)
0.0	0.1	GO:0097264	self proteolysis(GO:0097264)
0.0	0.1	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.0	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	0.0	GO:1904502	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0	0.0	GO:0060696	regulation of phospholipid catabolic process(GO:0060696)
0.0	0.0	GO:0008355	olfactory learning(GO:0008355)
0.0	0.0	GO:0090310	negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0	0.0	GO:0045988	negative regulation of striated muscle contraction(GO:0045988)
0.0	0.0	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.0	0.0	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	0.0	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.2	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.0	GO:0015747	urate transport(GO:0015747)
0.0	0.1	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0	0.0	GO:0007403	glial cell fate determination(GO:0007403)
0.0	0.0	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:0039702	viral budding via host ESCRT complex(GO:0039702)
0.0	0.0	GO:0003166	bundle of His development(GO:0003166)
0.0	0.0	GO:0044838	cell quiescence(GO:0044838)
0.0	0.0	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.0	0.0	GO:1904217	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:0097237	cellular response to toxic substance(GO:0097237)
0.0	0.0	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.0	0.0	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0	0.1	GO:0032793	positive regulation of CREB transcription factor activity(GO:0032793)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.0	0.0	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:1903392	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0	0.0	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.0	GO:1901026	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0	0.0	GO:0018002	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0	0.0	GO:0019244	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.0	0.1	GO:0009642	response to light intensity(GO:0009642)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.2	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.0	GO:0006235	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0	0.0	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.1	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.0	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0	0.0	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.1	GO:0043504	mitochondrial DNA repair(GO:0043504)
0.0	0.0	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.0	GO:0030007	cellular potassium ion homeostasis(GO:0030007)
0.0	0.1	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.0	GO:0015766	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.0	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.2	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0031933	telomeric heterochromatin(GO:0031933)
0.1	0.5	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.2	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.4	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.2	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	0.2	GO:0005767	secondary lysosome(GO:0005767)
0.0	0.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.3	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.4	GO:0071565	nBAF complex(GO:0071565)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.0	0.2	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.0	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.1	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0097413	Lewy body(GO:0097413)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.4	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.2	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.1	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	0.2	GO:0038201	TOR complex(GO:0038201)
0.0	0.1	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.1	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.1	GO:0043203	axon hillock(GO:0043203)
0.0	0.1	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.0	0.0	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.1	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.0	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	0.0	GO:0031523	Myb complex(GO:0031523)
0.0	0.2	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.0	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.1	GO:1990246	uniplex complex(GO:1990246)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.0	GO:0097443	sorting endosome(GO:0097443)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0090544	BAF-type complex(GO:0090544)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	0.3	GO:0008305	integrin complex(GO:0008305)
0.0	0.1	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.0	0.0	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0	0.0	GO:0005879	axonemal microtubule(GO:0005879)
0.0	0.2	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.2	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.0	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
0.0	0.1	GO:0002177	manchette(GO:0002177)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	0.4	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.4	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1	0.5	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.1	0.3	GO:0031433	telethonin binding(GO:0031433)
0.1	0.3	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.1	0.5	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	0.2	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	0.2	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.1	0.2	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.2	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.1	0.2	GO:0019770	IgG receptor activity(GO:0019770)
0.1	0.3	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.1	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.0	0.3	GO:0043910	CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.0	0.5	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.3	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0	0.1	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.0	0.2	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.0	0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.2	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.2	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.4	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.0	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.2	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.0	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.2	GO:0031432	titin binding(GO:0031432)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.0	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.1	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.2	GO:0042910	xenobiotic transporter activity(GO:0042910)
0.0	0.0	GO:0051373	FATZ binding(GO:0051373)
0.0	0.1	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.1	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.2	GO:0018640	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.0	0.1	GO:0070728	leucine binding(GO:0070728)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.1	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0005290	L-histidine transmembrane transporter activity(GO:0005290)
0.0	0.0	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.2	GO:0005542	folic acid binding(GO:0005542)
0.0	0.3	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.2	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.0	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.0	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.2	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.1	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.0	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.0	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.0	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.4	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.0	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.0	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.0	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.0	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0016726	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0	0.0	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.2	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.2	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.0	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.0	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.0	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	0.0	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0	0.0	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.0	0.0	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	0.1	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.0	GO:0043823	mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.0	0.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.0	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.1	GO:0043820	4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.0	0.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0	0.0	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.0	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
0.0	0.0	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	0.1	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.0	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0	0.1	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.0	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0	0.2	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.0	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.0	0.0	GO:1990190	peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0	0.3	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.0	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
0.0	0.0	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.0	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.0	0.0	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.0	0.2	GO:0031690	adrenergic receptor binding(GO:0031690)
0.0	0.0	GO:0008515	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.0	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.0	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	PID ALK2 PATHWAY	ALK2 signaling events
0.0	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.1	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.6	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.4	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.5	PID EPO PATHWAY	EPO signaling pathway
0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.2	PID IGF1 PATHWAY	IGF1 pathway
0.4	PID LKB1 PATHWAY	LKB1 signaling events
0.6	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.6	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	PID INSULIN PATHWAY	Insulin Pathway
0.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.4	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.2	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.4	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.2	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions