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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Foxo4

Z-value: 1.66

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Transcription factors associated with Foxo4

Gene Symbol	Gene ID	Gene Info
Foxo4 Ensembl NCBI MGI UniProt	ENSMUSG00000042903.7	forkhead box O4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chrX_101254026_101254193	Foxo4	419	0.685478	-0.88	2.0e-02	Click!
chrX_101253687_101253886	Foxo4	742	0.448899	0.72	1.1e-01	Click!
chrX_101254344_101254650	Foxo4	31	0.946488	-0.46	3.6e-01	Click!

Activity of the Foxo4 motif across conditions

Conditions sorted by the z-value of the Foxo4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_80974932_80975087	2.23	Gm11416	predicted gene 11416	71785	0.1
chr17_46052256_46052407	1.63	Vegfa	vascular endothelial growth factor A	19962	0.13
chr16_81353749_81353900	1.34	Gm49555	predicted gene, 49555	63662	0.13
chr15_62204050_62204201	1.16	Pvt1	Pvt1 oncogene	14098	0.23
chr1_51771064_51771215	1.12	Myo1b	myosin IB	260	0.93
chr6_120971997_120972148	1.11	Mical3	microtubule associated monooxygenase, calponin and LIM domain containing 3	10646	0.14
chr7_98404310_98404465	0.97	Gm44507	predicted gene 44507	11237	0.14
chr12_32764690_32765098	0.87	Nampt	nicotinamide phosphoribosyltransferase	54651	0.11
chr9_106231818_106232229	0.87	Alas1	aminolevulinic acid synthase 1	5061	0.11
chr8_121970329_121970503	0.86	Gm17709	predicted gene, 17709	3406	0.13
chr1_21248546_21248733	0.86	Gsta3	glutathione S-transferase, alpha 3	4882	0.13
chr16_37901578_37901755	0.84	Gpr156	G protein-coupled receptor 156	14830	0.14
chr7_3630090_3630358	0.83	Prpf31	pre-mRNA processing factor 31	165	0.62
chr7_87367938_87368104	0.82	Nox4	NADPH oxidase 4	121209	0.05
chr13_24378651_24378989	0.81	Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	2737	0.19
chr8_93185590_93185741	0.79	Gm45909	predicted gene 45909	5693	0.14
chr16_4414348_4414533	0.79	Adcy9	adenylate cyclase 9	5147	0.24
chr12_30200282_30200708	0.79	Sntg2	syntrophin, gamma 2	840	0.72
chr17_27621069_27621255	0.78	Nudt3	nudix (nucleotide diphosphate linked moiety X)-type motif 3	1231	0.25
chr9_123153278_123153441	0.74	Clec3b	C-type lectin domain family 3, member b	2413	0.18
chr7_98351265_98351558	0.73	Tsku	tsukushi, small leucine rich proteoglycan	8668	0.17
chr3_133725268_133725422	0.72	Gm40153	predicted gene, 40153	61954	0.1
chr9_122164867_122165083	0.70	Snrk	SNF related kinase	1106	0.4
chr2_177468355_177468573	0.70	Zfp970	zinc finger protein 970	3618	0.19
chr17_10310410_10310561	0.70	Qk	quaking	8876	0.24
chr8_70832381_70832563	0.69	Arrdc2	arrestin domain containing 2	4115	0.09
chr8_66494561_66494830	0.68	Gm32568	predicted gene, 32568	364	0.85
chr16_77405236_77405411	0.67	Gm21816	predicted gene, 21816	4476	0.13
chr3_107793106_107793505	0.67	Gm43233	predicted gene 43233	11449	0.12
chr7_119855181_119855332	0.66	Dcun1d3	DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)	6548	0.15
chr12_76369660_76370048	0.65	Zbtb25	zinc finger and BTB domain containing 25	252	0.62
chr8_93195399_93195725	0.65	Ces1d	carboxylesterase 1D	2215	0.21
chr6_108426324_108426499	0.63	Itpr1	inositol 1,4,5-trisphosphate receptor 1	8534	0.22
chr3_96630277_96630623	0.62	Rbm8a	RNA binding motif protein 8a	253	0.67
chr6_115668757_115668908	0.61	Raf1	v-raf-leukemia viral oncogene 1	7132	0.12
chr7_124491258_124491413	0.61	Gm23168	predicted gene, 23168	1571	0.43
chr9_103301161_103301484	0.60	1300017J02Rik	RIKEN cDNA 1300017J02 gene	3760	0.19
chr10_77629279_77629435	0.60	Ube2g2	ubiquitin-conjugating enzyme E2G 2	6979	0.08
chr6_127044968_127045119	0.60	Fgf23	fibroblast growth factor 23	27859	0.1
chr17_84137478_84137775	0.60	Gm19696	predicted gene, 19696	112	0.96
chr6_42360337_42360550	0.59	Zyx	zyxin	5306	0.09
chr15_3487391_3487651	0.58	Ghr	growth hormone receptor	15877	0.27
chr5_146246268_146246419	0.58	Gm15739	predicted gene 15739	2208	0.21
chr1_59159262_59159448	0.58	Mpp4	membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)	687	0.57
chr8_46918583_46918754	0.58	1700011L03Rik	RIKEN cDNA 1700011L03 gene	30131	0.16
chr1_21263057_21263217	0.57	Gm28836	predicted gene 28836	8456	0.11
chr17_46454562_46454932	0.57	Gm5093	predicted gene 5093	14650	0.09
chr15_58942719_58942985	0.56	Ndufb9	NADH:ubiquinone oxidoreductase subunit B9	9044	0.13
chr12_71941808_71941989	0.56	Daam1	dishevelled associated activator of morphogenesis 1	52168	0.13
chr12_8785591_8785796	0.56	Sdc1	syndecan 1	13890	0.17
chr17_75539486_75539637	0.56	Fam98a	family with sequence similarity 98, member A	1011	0.65
chr7_126667358_126667803	0.56	Sgf29	SAGA complex associated factor 29	3787	0.08
chr10_121349997_121350168	0.55	Gm48435	predicted gene, 48435	378	0.73
chr6_31260546_31260737	0.55	2210408F21Rik	RIKEN cDNA 2210408F21 gene	17207	0.15
chr16_43236306_43236477	0.55	Zbtb20	zinc finger and BTB domain containing 20	352	0.9
chr6_148945956_148946305	0.55	Sinhcaf	SIN3-HDAC complex associated factor	25	0.94
chr10_23851933_23852432	0.55	Vnn3	vanin 3	720	0.56
chr16_77351638_77351789	0.54	Mir99ahg	Mir99a and Mirlet7c-1 host gene (non-protein coding)	22209	0.13
chr4_122955991_122956232	0.54	Mfsd2a	major facilitator superfamily domain containing 2A	3879	0.16
chr9_103213949_103214100	0.53	Trf	transferrin	2018	0.29
chr11_69367124_69367290	0.53	Chd3	chromodomain helicase DNA binding protein 3	2184	0.13
chr19_53898302_53898495	0.53	Pdcd4	programmed cell death 4	4568	0.17
chr10_3114251_3114403	0.53	Gm3318	predicted gene 3318	4660	0.15
chr1_88137698_88137920	0.53	Ugt1a6a	UDP glucuronosyltransferase 1 family, polypeptide A6A	569	0.47
chr13_67194609_67194806	0.53	Zfp455	zinc finger protein 455	172	0.88
chr7_134381581_134381749	0.52	D7Ertd443e	DNA segment, Chr 7, ERATO Doi 443, expressed	3996	0.35
chr11_120807385_120807536	0.52	Fasn	fatty acid synthase	1145	0.28
chr9_25592470_25592621	0.51	Gm25346	predicted gene, 25346	22740	0.2
chr6_94669947_94670290	0.51	Lrig1	leucine-rich repeats and immunoglobulin-like domains 1	8747	0.23
chr13_102593887_102594038	0.51	Gm29927	predicted gene, 29927	3677	0.27
chr1_193934263_193934432	0.49	Gm21362	predicted gene, 21362	67338	0.14
chr5_130009254_130009405	0.49	Asl	argininosuccinate lyase	5393	0.12
chr5_28045123_28045274	0.49	Gm43611	predicted gene 43611	8792	0.16
chr18_32432396_32432575	0.48	Bin1	bridging integrator 1	4451	0.19
chr3_118601540_118602026	0.48	Dpyd	dihydropyrimidine dehydrogenase	39597	0.15
chr17_46468128_46468340	0.48	Gm47119	predicted gene, 47119	8273	0.1
chr2_25292972_25293141	0.48	Grin1os	glutamate receptor, ionotropic, NMDA1 (zeta 1), opposite strand	1836	0.11
chr7_79273801_79273960	0.48	Abhd2	abhydrolase domain containing 2	626	0.48
chr1_88102885_88103050	0.47	Ugt1a7c	UDP glucuronosyltransferase 1 family, polypeptide A7C	285	0.43
chr2_122244595_122244916	0.47	Sord	sorbitol dehydrogenase	10006	0.11
chr4_6265892_6266043	0.47	Gm11798	predicted gene 11798	5002	0.21
chr9_35267693_35268345	0.47	Rpusd4	RNA pseudouridylate synthase domain containing 4	154	0.57
chr7_44207877_44208028	0.47	Klk1b4	kallikrein 1-related pepidase b4	517	0.41
chr8_70234885_70235099	0.46	Sugp2	SURP and G patch domain containing 2	369	0.55
chr10_80958504_80958805	0.45	Gm3828	predicted gene 3828	3944	0.12
chr3_129744894_129745074	0.45	Gm42650	predicted gene 42650	356	0.81
chr7_120843161_120843378	0.45	Eef2k	eukaryotic elongation factor-2 kinase	298	0.86
chr19_44044543_44044826	0.45	Cyp2c23	cytochrome P450, family 2, subfamily c, polypeptide 23	15476	0.13
chr1_67192197_67192413	0.45	Gm15668	predicted gene 15668	56895	0.12
chr11_11961796_11961953	0.44	Grb10	growth factor receptor bound protein 10	5850	0.23
chr18_12224214_12224414	0.44	Npc1	NPC intracellular cholesterol transporter 1	227	0.91
chr6_54251791_54251942	0.44	Gm15527	predicted gene 15527	3045	0.25
chr19_32956944_32957156	0.44	Gm36860	predicted gene, 36860	23013	0.24
chr7_99173210_99173446	0.44	Dgat2	diacylglycerol O-acyltransferase 2	3222	0.17
chr6_129476147_129476311	0.44	Clec7a	C-type lectin domain family 7, member a	3450	0.12
chr2_172449892_172450043	0.43	Rtf2	replication termination factor 2	3010	0.17
chr5_24976790_24976954	0.43	1500035N22Rik	RIKEN cDNA 1500035N22 gene	8970	0.18
chr15_83564154_83564331	0.43	Tspo	translocator protein	367	0.52
chr1_87764160_87764454	0.42	Atg16l1	autophagy related 16-like 1 (S. cerevisiae)	2594	0.19
chr10_69258899_69259108	0.42	Rhobtb1	Rho-related BTB domain containing 1	6634	0.21
chr9_59617318_59618012	0.42	Parp6	poly (ADP-ribose) polymerase family, member 6	285	0.88
chr19_5796124_5796526	0.42	Malat1	metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)	627	0.48
chr7_90080690_90080897	0.42	Gm5341	predicted pseudogene 5341	27175	0.1
chr4_150393280_150393601	0.42	Rere	arginine glutamic acid dipeptide (RE) repeats	12954	0.22
chr10_69214299_69214646	0.41	Rhobtb1	Rho-related BTB domain containing 1	830	0.51
chr1_62053011_62053191	0.41	Gm29641	predicted gene 29641	42238	0.17
chr14_14789749_14789914	0.41	Slc4a7	solute carrier family 4, sodium bicarbonate cotransporter, member 7	3904	0.26
chr9_74892937_74893252	0.41	Onecut1	one cut domain, family member 1	26610	0.14
chr9_107303087_107303371	0.41	Gm17041	predicted gene 17041	1391	0.24
chr6_47758577_47758728	0.41	Rpl31-ps7	ribosomal protein L31, pseudogene 7	27722	0.12
chr5_40691768_40691967	0.41	Gm23022	predicted gene, 23022	285938	0.01
chr8_73953761_73954148	0.40	Gm7948	predicted gene 7948	82261	0.11
chr7_19573353_19573652	0.40	Gemin7	gem nuclear organelle associated protein 7	117	0.92
chr7_99130459_99130779	0.40	Gm44975	predicted gene 44975	7160	0.13
chr2_27694949_27695100	0.40	Rxra	retinoid X receptor alpha	14268	0.25
chr11_115815536_115815882	0.40	Tsen54	tRNA splicing endonuclease subunit 54	11	0.95
chr2_38225178_38225332	0.40	Gm44455	predicted gene, 44455	133	0.96
chr10_68093985_68094164	0.40	Arid5b	AT rich interactive domain 5B (MRF1-like)	42552	0.15
chr1_133712710_133712943	0.39	Atp2b4	ATPase, Ca++ transporting, plasma membrane 4	5103	0.15
chr11_112038554_112038713	0.39	Gm11679	predicted gene 11679	4945	0.32
chr7_140104126_140104290	0.39	Fuom	fucose mutarotase	1767	0.18
chr10_124590350_124590536	0.39	4930503E24Rik	RIKEN cDNA 4930503E24 gene	67005	0.14
chr11_120560412_120560649	0.38	P4hb	prolyl 4-hydroxylase, beta polypeptide	706	0.37
chr5_125528257_125528432	0.38	Tmem132b	transmembrane protein 132B	3430	0.21
chr9_96983617_96983972	0.38	Spsb4	splA/ryanodine receptor domain and SOCS box containing 4	401	0.83
chr11_78437291_78437469	0.38	Gm11195	predicted gene 11195	6727	0.1
chr2_70642763_70643161	0.38	Gorasp2	golgi reassembly stacking protein 2	18614	0.14
chr6_47772904_47773093	0.37	Rpl31-ps7	ribosomal protein L31, pseudogene 7	13376	0.13
chr5_123226541_123226692	0.37	Psmd9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	1574	0.24
chr10_81414192_81414360	0.37	Mir1191b	microRNA 1191b	2021	0.11
chr9_108089036_108089891	0.37	Apeh	acylpeptide hydrolase	943	0.28
chr3_118606217_118606485	0.37	Dpyd	dihydropyrimidine dehydrogenase	44165	0.15
chr19_20626512_20626720	0.37	Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1	24655	0.19
chr12_32488584_32488761	0.37	Gm17820	predicted gene, 17820	1254	0.55
chr11_69192936_69193104	0.36	Alox8	arachidonate 8-lipoxygenase	4364	0.12
chr13_101914612_101914792	0.36	Gm17832	predicted gene, 17832	5718	0.26
chr2_26931955_26932305	0.36	Surf4	surfeit gene 4	1253	0.2
chr2_30268240_30268600	0.36	Phyhd1	phytanoyl-CoA dioxygenase domain containing 1	1557	0.21
chr6_125309060_125309481	0.36	Ltbr	lymphotoxin B receptor	295	0.81
chr2_160646625_160646797	0.36	Top1	topoisomerase (DNA) I	731	0.65
chr6_47664591_47664742	0.36	Gm44141	predicted gene, 44141	29369	0.16
chr11_113140051_113140245	0.36	2610035D17Rik	RIKEN cDNA 2610035D17 gene	32929	0.22
chr14_30887527_30887997	0.36	Itih4	inter alpha-trypsin inhibitor, heavy chain 4	1241	0.32
chr8_40564488_40564639	0.36	Vps37a	vacuolar protein sorting 37A	21139	0.15
chr10_79897700_79897893	0.36	Med16	mediator complex subunit 16	1889	0.11
chr9_44083899_44084207	0.35	Usp2	ubiquitin specific peptidase 2	886	0.32
chr4_150869904_150870096	0.35	Errfi1	ERBB receptor feedback inhibitor 1	14927	0.13
chr11_88512888_88513073	0.35	Msi2	musashi RNA-binding protein 2	77167	0.09
chr18_33337551_33337772	0.35	Gm5503	predicted gene 5503	47294	0.17
chr2_132263417_132263641	0.35	Cds2	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2	288	0.88
chr15_55117700_55118060	0.35	Gm9920	predicted gene 9920	4203	0.17
chr13_56134012_56134235	0.34	Macroh2a1	macroH2A.1 histone	702	0.66
chr16_24902438_24902606	0.34	Gm22672	predicted gene, 22672	18349	0.23
chr10_77587179_77587612	0.34	Pttg1ip	pituitary tumor-transforming 1 interacting protein	1999	0.18
chr18_56414797_56414976	0.34	Gramd3	GRAM domain containing 3	4284	0.23
chr6_92183686_92183906	0.34	Mrps25	mitochondrial ribosomal protein S25	175	0.93
chr4_8733319_8733778	0.34	Chd7	chromodomain helicase DNA binding protein 7	17890	0.25
chr14_67055418_67055773	0.34	Ppp2r2a	protein phosphatase 2, regulatory subunit B, alpha	12066	0.16
chr5_77331140_77331293	0.34	Polr2b	polymerase (RNA) II (DNA directed) polypeptide B	5326	0.15
chr3_98013087_98013258	0.34	Notch2	notch 2	355	0.87
chr1_164559930_164560081	0.33	D630023O14Rik	RIKEN cDNA D630023O14 gene	15450	0.17
chr1_13639776_13639929	0.33	Lactb2	lactamase, beta 2	1441	0.37
chr19_41656077_41656246	0.33	Slit1	slit guidance ligand 1	47631	0.13
chr14_18232288_18232439	0.33	Nr1d2	nuclear receptor subfamily 1, group D, member 2	6648	0.15
chr6_142345778_142346191	0.33	Pyroxd1	pyridine nucleotide-disulphide oxidoreductase domain 1	306	0.86
chr9_65188991_65189142	0.33	Parp16	poly (ADP-ribose) polymerase family, member 16	6287	0.13
chr2_91072228_91072550	0.33	Slc39a13	solute carrier family 39 (metal ion transporter), member 13	1972	0.19
chr19_40349126_40349331	0.33	Sorbs1	sorbin and SH3 domain containing 1	8634	0.21
chr6_47651586_47651824	0.33	Gm44141	predicted gene, 44141	16408	0.19
chr4_109122898_109123075	0.33	Osbpl9	oxysterol binding protein-like 9	4950	0.24
chr19_47451572_47451805	0.32	Sh3pxd2a	SH3 and PX domains 2A	12559	0.19
chr18_53291057_53291223	0.32	Snx24	sorting nexing 24	45371	0.16
chr10_95318232_95318691	0.32	Gm48882	predicted gene, 48882	214	0.9
chr19_34524558_34524859	0.32	Lipa	lysosomal acid lipase A	2703	0.19
chr10_4621590_4621757	0.32	Esr1	estrogen receptor 1 (alpha)	9652	0.24
chr2_128971807_128971990	0.32	Gm10762	predicted gene 10762	3854	0.12
chr6_47768512_47768677	0.32	Rpl31-ps7	ribosomal protein L31, pseudogene 7	17780	0.13
chr6_47740769_47740920	0.32	Rpl31-ps7	ribosomal protein L31, pseudogene 7	45530	0.1
chr2_152733626_152733777	0.32	Id1	inhibitor of DNA binding 1, HLH protein	2550	0.16
chr3_144113744_144114175	0.31	Gm34078	predicted gene, 34078	21795	0.21
chr3_133749142_133749410	0.31	Gm6135	prediticted gene 6135	42228	0.15
chr12_39373542_39373711	0.31	Gm47855	predicted gene, 47855	24930	0.22
chr7_128528420_128528640	0.31	Bag3	BCL2-associated athanogene 3	4914	0.13
chr10_95385978_95386158	0.31	Socs2	suppressor of cytokine signaling 2	6899	0.14
chr15_87326683_87326854	0.31	A930027H12Rik	RIKEN cDNA A930027H12 gene	83218	0.1
chr15_102028397_102029113	0.31	Krt18	keratin 18	575	0.64
chr10_120227241_120227692	0.31	Llph	LLP homolog, long-term synaptic facilitation (Aplysia)	280	0.88
chr5_89422914_89423162	0.31	Gc	vitamin D binding protein	12590	0.26
chr7_99163511_99163819	0.31	Dgat2	diacylglycerol O-acyltransferase 2	6441	0.13
chr11_12464170_12464384	0.31	Cobl	cordon-bleu WH2 repeat	475	0.89
chr3_95871977_95872183	0.30	C920021L13Rik	RIKEN cDNA C920021L13 gene	549	0.36
chr14_103070733_103070991	0.30	Cln5	ceroid-lipofuscinosis, neuronal 5	646	0.63
chr9_102990799_102990950	0.30	Slco2a1	solute carrier organic anion transporter family, member 2a1	2162	0.27
chr3_30506438_30507337	0.30	Mecom	MDS1 and EVI1 complex locus	2600	0.2
chr12_85824517_85825257	0.30	Ttll5	tubulin tyrosine ligase-like family, member 5	81	0.8
chr17_28428613_28428954	0.30	Fkbp5	FK506 binding protein 5	154	0.91
chr4_103933550_103933744	0.30	Gm12719	predicted gene 12719	5894	0.25
chr9_71027981_71028199	0.30	Lipc	lipase, hepatic	75864	0.09
chr11_115165779_115165997	0.30	Slc9a3r1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	2547	0.17
chr12_35674441_35674592	0.30	9130015A21Rik	RIKEN cDNA 9130015A21 gene	13	0.98

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxo4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1	0.4	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.4	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.1	0.3	GO:0006768	biotin metabolic process(GO:0006768)
0.1	0.3	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	0.3	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.1	0.2	GO:0002572	pro-T cell differentiation(GO:0002572)
0.1	0.3	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1	0.5	GO:0072602	interleukin-4 secretion(GO:0072602)
0.1	0.2	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061419)
0.1	0.2	GO:0006059	hexitol metabolic process(GO:0006059)
0.1	0.3	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1	0.6	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.1	0.3	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	0.2	GO:0021553	olfactory nerve development(GO:0021553)
0.1	0.6	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1	0.2	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.1	0.2	GO:1903288	regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.1	0.2	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.2	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.1	0.1	GO:0009698	phenylpropanoid metabolic process(GO:0009698)
0.1	0.1	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.1	0.2	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.1	0.2	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1	0.3	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1	0.2	GO:0030576	Cajal body organization(GO:0030576)
0.1	0.3	GO:0006559	L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1	0.2	GO:0097460	ferrous iron import into cell(GO:0097460)
0.1	0.2	GO:1904749	regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.1	0.2	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.1	GO:0043096	purine nucleobase salvage(GO:0043096)
0.0	0.2	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.3	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.2	GO:0021747	cochlear nucleus development(GO:0021747)
0.0	0.2	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.0	0.2	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.0	0.2	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.0	0.1	GO:0061144	alveolar secondary septum development(GO:0061144)
0.0	0.1	GO:1900368	regulation of RNA interference(GO:1900368)
0.0	0.1	GO:0051944	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0	0.3	GO:0009162	deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0	0.3	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.1	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.2	GO:0060018	astrocyte fate commitment(GO:0060018)
0.0	0.1	GO:0035984	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.0	0.1	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.3	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.2	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.0	0.3	GO:0060526	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.1	GO:0038027	apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.0	0.1	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.1	GO:0034473	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0	0.1	GO:1904139	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0	0.3	GO:0060613	fat pad development(GO:0060613)
0.0	0.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.1	GO:0006068	ethanol catabolic process(GO:0006068)
0.0	0.1	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.2	GO:0042045	epithelial fluid transport(GO:0042045)
0.0	0.1	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.2	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.2	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.1	GO:0060988	lipid tube assembly(GO:0060988)
0.0	0.2	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.0	0.2	GO:0032532	regulation of microvillus length(GO:0032532)
0.0	0.1	GO:1904261	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0	0.4	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.0	GO:1902116	negative regulation of organelle assembly(GO:1902116)
0.0	0.3	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.1	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.2	GO:2000650	negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.2	GO:1903551	regulation of extracellular exosome assembly(GO:1903551)
0.0	0.1	GO:0045608	negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0	0.1	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.1	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.2	GO:0021540	corpus callosum morphogenesis(GO:0021540)
0.0	0.1	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.2	GO:1901841	regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0	0.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.1	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.2	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0	0.1	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.0	0.2	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.2	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.2	GO:0006265	DNA topological change(GO:0006265)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.1	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.0	GO:0033122	negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0	0.1	GO:0035279	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0	0.1	GO:0010963	regulation of L-arginine import(GO:0010963)
0.0	0.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.2	GO:0034372	very-low-density lipoprotein particle remodeling(GO:0034372)
0.0	0.1	GO:0003383	apical constriction(GO:0003383)
0.0	0.2	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.2	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.3	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.0	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0	0.2	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.1	GO:0071494	cellular response to UV-C(GO:0071494)
0.0	0.1	GO:0060112	generation of ovulation cycle rhythm(GO:0060112)
0.0	0.1	GO:0032741	positive regulation of interleukin-18 production(GO:0032741)
0.0	0.0	GO:1902306	negative regulation of sodium ion transmembrane transport(GO:1902306)
0.0	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.1	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0	0.0	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.0	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.0	0.0	GO:0010873	positive regulation of cholesterol esterification(GO:0010873)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.3	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0	0.0	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.2	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0	0.0	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0	0.1	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.2	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.1	GO:1903660	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.1	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	0.4	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.1	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	0.1	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0061010	gall bladder development(GO:0061010)
0.0	0.1	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.0	0.1	GO:1905049	negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0	0.0	GO:0097167	circadian regulation of translation(GO:0097167)
0.0	0.0	GO:0043366	beta selection(GO:0043366)
0.0	0.0	GO:0060523	prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0	0.4	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.1	GO:0060353	regulation of cell adhesion molecule production(GO:0060353)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.0	GO:2000646	positive regulation of receptor catabolic process(GO:2000646)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.3	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.1	GO:0036022	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0	0.1	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0	0.1	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.4	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.5	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.2	GO:0061157	mRNA destabilization(GO:0061157)
0.0	0.1	GO:0015772	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.0	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0071397	cellular response to cholesterol(GO:0071397)
0.0	0.2	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.2	GO:0006622	protein targeting to lysosome(GO:0006622)
0.0	0.1	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.0	0.0	GO:1905048	regulation of metallopeptidase activity(GO:1905048)
0.0	0.1	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.1	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.0	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.0	0.0	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.0	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.0	0.1	GO:0019348	dolichol metabolic process(GO:0019348)
0.0	0.2	GO:0031297	replication fork processing(GO:0031297)
0.0	0.2	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.3	GO:0046464	neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0	0.1	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0	0.0	GO:0033566	gamma-tubulin complex localization(GO:0033566)
0.0	0.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.0	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.1	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.0	GO:0021943	formation of radial glial scaffolds(GO:0021943)
0.0	0.1	GO:0002636	positive regulation of germinal center formation(GO:0002636)
0.0	0.0	GO:0002071	glandular epithelial cell maturation(GO:0002071)
0.0	0.0	GO:0042938	dipeptide transport(GO:0042938)
0.0	0.2	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0	0.1	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0	0.0	GO:0051410	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0	0.1	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.0	GO:1904431	positive regulation of t-circle formation(GO:1904431)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.3	GO:0035418	protein localization to synapse(GO:0035418)
0.0	0.1	GO:0090166	Golgi disassembly(GO:0090166)
0.0	0.0	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.0	0.1	GO:0003283	atrial septum development(GO:0003283)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0071280	cellular response to copper ion(GO:0071280)
0.0	0.0	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.0	GO:0018002	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0	0.0	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0	1.0	GO:0030048	actin filament-based movement(GO:0030048)
0.0	0.0	GO:0010909	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0	0.0	GO:0042167	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.1	GO:0030575	nuclear body organization(GO:0030575)
0.0	0.0	GO:0021586	pons maturation(GO:0021586)
0.0	0.0	GO:0051594	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.0	0.1	GO:0090520	sphingolipid mediated signaling pathway(GO:0090520)
0.0	0.0	GO:0050883	musculoskeletal movement, spinal reflex action(GO:0050883)
0.0	0.7	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.0	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.1	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.0	0.0	GO:0060913	cardiac cell fate determination(GO:0060913)
0.0	0.0	GO:0035964	COPI-coated vesicle budding(GO:0035964)
0.0	0.0	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.0	0.1	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.0	GO:0007228	positive regulation of hh target transcription factor activity(GO:0007228)
0.0	0.1	GO:0060148	positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.0	0.0	GO:1904177	regulation of adipose tissue development(GO:1904177)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.0	GO:0070432	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432)
0.0	0.0	GO:0090155	negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
0.0	0.0	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.1	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.0	0.1	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.0	GO:2000409	positive regulation of T cell extravasation(GO:2000409)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.0	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.2	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.0	0.0	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.0	0.0	GO:0006382	adenosine to inosine editing(GO:0006382)
0.0	0.4	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.0	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.0	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.0	GO:0044038	cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
0.0	0.0	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.0	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.0	0.0	GO:0036089	cleavage furrow formation(GO:0036089)
0.0	0.1	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.0	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.1	GO:0046606	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.0	GO:0042374	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0	0.0	GO:0002838	negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.0	0.0	GO:2001055	positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.0	0.0	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.0	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.0	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.1	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.0	GO:0061724	lipophagy(GO:0061724) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0	0.3	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.0	GO:2001182	regulation of interleukin-12 secretion(GO:2001182)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.0	GO:2001046	positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.0	0.0	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.1	GO:0051767	nitric-oxide synthase biosynthetic process(GO:0051767) regulation of nitric-oxide synthase biosynthetic process(GO:0051769)
0.0	0.1	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0	0.1	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.0	0.0	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.0	GO:0015819	lysine transport(GO:0015819)
0.0	0.0	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.1	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.0	GO:0090399	replicative senescence(GO:0090399)
0.0	0.0	GO:0046060	dATP metabolic process(GO:0046060)
0.0	0.0	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.0	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.0	GO:0001887	selenium compound metabolic process(GO:0001887)
0.0	0.1	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.0	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.1	0.3	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	0.5	GO:0005775	vacuolar lumen(GO:0005775)
0.1	0.2	GO:0097454	Schwann cell microvillus(GO:0097454)
0.1	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.2	GO:1990357	terminal web(GO:1990357)
0.1	1.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	0.2	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	0.3	GO:0001652	granular component(GO:0001652)
0.1	0.4	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	0.5	GO:0005687	U4 snRNP(GO:0005687)
0.1	0.2	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.0	0.1	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	0.2	GO:0001651	dense fibrillar component(GO:0001651)
0.0	0.4	GO:0034719	SMN-Sm protein complex(GO:0034719)
0.0	0.2	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.4	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.0	0.1	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.1	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.2	GO:0044214	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.6	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.1	GO:0070939	Dsl1p complex(GO:0070939)
0.0	0.1	GO:0044308	axonal spine(GO:0044308)
0.0	0.3	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	0.3	GO:0033391	chromatoid body(GO:0033391)
0.0	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.5	GO:0032420	stereocilium(GO:0032420)
0.0	0.1	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.0	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.1	GO:1990812	growth cone filopodium(GO:1990812)
0.0	0.1	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.1	GO:0045180	basal cortex(GO:0045180)
0.0	0.1	GO:0005712	chiasma(GO:0005712)
0.0	0.2	GO:0010369	chromocenter(GO:0010369)
0.0	0.0	GO:0032280	symmetric synapse(GO:0032280)
0.0	0.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.0	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.2	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0031414	N-terminal protein acetyltransferase complex(GO:0031414)
0.0	0.2	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0043194	axon initial segment(GO:0043194)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0097109	neuroligin family protein binding(GO:0097109)
0.2	0.5	GO:0030621	U4 snRNA binding(GO:0030621)
0.1	0.4	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.3	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.4	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.1	1.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	0.3	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.1	0.3	GO:0004771	sterol esterase activity(GO:0004771)
0.1	0.3	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.2	GO:0048408	epidermal growth factor binding(GO:0048408)
0.1	0.2	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.1	0.4	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.1	0.2	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	0.1	GO:0038181	bile acid receptor activity(GO:0038181)
0.1	0.2	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.1	0.2	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.1	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.0	0.3	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.3	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.2	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0	0.1	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0	0.3	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.2	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:1990459	transferrin receptor binding(GO:1990459)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0070878	primary miRNA binding(GO:0070878)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.2	GO:0016936	galactoside binding(GO:0016936)
0.0	0.6	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0038100	nodal binding(GO:0038100)
0.0	0.1	GO:0070883	pre-miRNA binding(GO:0070883)
0.0	0.2	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0018565	2,3-dihydroxy DDT 1,2-dioxygenase activity(GO:0018542) phenanthrene dioxygenase activity(GO:0018555) 2,2',3-trihydroxybiphenyl dioxygenase activity(GO:0018556) 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity(GO:0018557) 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity(GO:0018558) 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity(GO:0018559) protocatechuate 3,4-dioxygenase type II activity(GO:0018560) 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity(GO:0018561) 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity(GO:0018562) 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity(GO:0018563) carbazole 1,9a-dioxygenase activity(GO:0018564) dihydroxydibenzothiophene dioxygenase activity(GO:0018565) 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity(GO:0018566) styrene dioxygenase activity(GO:0018567) 3,4-dihydroxyphenanthrene dioxygenase activity(GO:0018568) hydroquinone 1,2-dioxygenase activity(GO:0018569) p-cumate 2,3-dioxygenase activity(GO:0018570) 2,3-dihydroxy-p-cumate dioxygenase activity(GO:0018571) 3,5-dichlorocatechol 1,2-dioxygenase activity(GO:0018572) 2-aminophenol 1,6-dioxygenase activity(GO:0018573) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity(GO:0018574) chlorocatechol 1,2-dioxygenase activity(GO:0018575) catechol dioxygenase activity(GO:0019114) dihydroxyfluorene dioxygenase activity(GO:0019117) 5-aminosalicylate dioxygenase activity(GO:0034543) 3-hydroxy-2-naphthoate 2,3-dioxygenase activity(GO:0034803) benzo(a)pyrene 11,12-dioxygenase activity(GO:0034806) benzo(a)pyrene 4,5-dioxygenase activity(GO:0034808) 4,5-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034810) benzo(a)pyrene 9,10-dioxygenase activity(GO:0034811) 9,10-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034812) benzo(a)pyrene 7,8-dioxygenase activity(GO:0034813) 7,8-dihydroxy benzo(a)pyrene dioxygenase activity(GO:0034814) 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity(GO:0034827) 2-mercaptobenzothiazole dioxygenase activity(GO:0034834) pyridine-3,4-diol dioxygenase activity(GO:0034895) pyrene dioxygenase activity(GO:0034920) 4,5-dihydroxypyrene dioxygenase activity(GO:0034922) phenanthrene-4-carboxylate dioxygenase activity(GO:0034934) tetrachlorobenzene dioxygenase activity(GO:0034935) 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity(GO:0034936) 2,3-dihydroxydiphenyl ether dioxygenase activity(GO:0034955) diphenyl ether 1,2-dioxygenase activity(GO:0034956) arachidonate 8(S)-lipoxygenase activity(GO:0036403) 4-hydroxycatechol 1,2-dioxygenase activity(GO:0047074)
0.0	0.4	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.1	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.5	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.2	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.4	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.3	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.2	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.2	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.0	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.0	0.0	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.0	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.2	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0032551	UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0	0.1	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.2	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.1	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.1	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.3	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.5	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.1	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.0	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.0	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.2	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.3	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0008506	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.1	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.1	GO:0018631	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0	0.1	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.1	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.3	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.0	GO:0005119	smoothened binding(GO:0005119)
0.0	0.0	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0019145	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0070546	L-phenylalanine aminotransferase activity(GO:0070546)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0001055	RNA polymerase II activity(GO:0001055)
0.0	0.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.0	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.0	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.0	0.2	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.1	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.1	GO:0071253	connexin binding(GO:0071253)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.4	GO:0034892	prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.3	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.0	0.0	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.0	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.1	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.0	0.0	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0	0.0	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.2	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.2	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.0	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.0	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.1	GO:0031386	protein tag(GO:0031386)
0.0	0.1	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.0	GO:0002046	opsin binding(GO:0002046)
0.0	0.4	GO:0016749	N-succinyltransferase activity(GO:0016749)
0.0	0.0	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0	0.0	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.0	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	0.1	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.4	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.6	ST ADRENERGIC	Adrenergic Pathway
0.0	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.4	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	PID FGF PATHWAY	FGF signaling pathway
0.0	PID IFNG PATHWAY	IFN-gamma pathway
0.8	PID P73PATHWAY	p73 transcription factor network
0.2	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.4	REACTOME INSULIN RECEPTOR SIGNALLING CASCADE	Genes involved in Insulin receptor signalling cascade
0.1	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.1	0.1	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.5	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.0	REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	Genes involved in Signaling by the B Cell Receptor (BCR)
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.2	REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	Genes involved in Acetylcholine Binding And Downstream Events
0.0	0.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.2	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.2	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.1	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.0	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.3	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.0	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression

Results for Foxo4

Z-value: 1.66

Motif logo

Transcription factors associated with Foxo4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Foxo4 motif across conditions

Conditions sorted by the z-value of the Foxo4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxo4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: