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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Gli1

Z-value: 0.66

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Transcription factors associated with Gli1

Gene Symbol	Gene ID	Gene Info
Gli1 Ensembl NCBI MGI UniProt	ENSMUSG00000025407.6	Gli1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Gli1	chr10_127342400_127342556	504	0.573543	-0.36	4.9e-01	Click!
Gli1	chr10_127339210_127339386	661	0.452215	0.19	7.2e-01	Click!
Gli1	chr10_127338950_127339111	929	0.317120	-0.17	7.5e-01	Click!
Gli1	chr10_127342165_127342330	273	0.786497	0.03	9.5e-01	Click!
Gli1	chr10_127341973_127342136	80	0.924080	0.00	1.0e+00	Click!

Activity of the Gli1 motif across conditions

Conditions sorted by the z-value of the Gli1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_33430783_33430934	0.46	Zbtb34	zinc finger and BTB domain containing 34	459	0.78
chr13_93627456_93627944	0.45	Gm15622	predicted gene 15622	2318	0.25
chr19_3840572_3840723	0.45	Chka	choline kinase alpha	11126	0.09
chr15_100625793_100625948	0.40	Dazap2	DAZ associated protein 2	9538	0.08
chr2_103846113_103846314	0.34	Gm13879	predicted gene 13879	2557	0.13
chr3_108011504_108011674	0.33	Gstm1	glutathione S-transferase, mu 1	1727	0.15
chr11_86954758_86954966	0.33	Ypel2	yippee like 2	17162	0.18
chr5_33726324_33726568	0.32	Fgfr3	fibroblast growth factor receptor 3	2674	0.15
chr7_127804168_127804541	0.30	9430064I24Rik	RIKEN cDNA 9430064I24 gene	1592	0.16
chr2_167260546_167260697	0.30	Ptgis	prostaglandin I2 (prostacyclin) synthase	20017	0.13
chr15_27560020_27560329	0.30	Ank	progressive ankylosis	11273	0.16
chr8_124843018_124843401	0.29	Gm16163	predicted gene 16163	11511	0.11
chr11_119056746_119056911	0.28	Cbx8	chromobox 8	15859	0.14
chr19_46133855_46134398	0.27	Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	2229	0.19
chr6_141875439_141875590	0.25	Gm30784	predicted gene, 30784	9156	0.21
chr3_121168919_121169132	0.25	Gm10652	predicted gene 10652	369	0.83
chr10_59978256_59978409	0.25	Anapc16	anaphase promoting complex subunit 16	12051	0.16
chr8_13889986_13890137	0.24	Coprs	coordinator of PRMT5, differentiation stimulator	71	0.95
chr10_76580112_76580438	0.22	Ftcd	formiminotransferase cyclodeaminase	4623	0.13
chr1_72836877_72837059	0.22	Igfbp2	insulin-like growth factor binding protein 2	11646	0.21
chr5_110809507_110809658	0.22	Ulk1	unc-51 like kinase 1	471	0.7
chr11_60113222_60113373	0.21	4930412M03Rik	RIKEN cDNA 4930412M03 gene	1933	0.28
chr15_89378952_89379124	0.21	Odf3b	outer dense fiber of sperm tails 3B	35	0.93
chr6_117431300_117431501	0.21	Gm4640	predicted gene 4640	7783	0.22
chr12_28898892_28899474	0.21	Gm31508	predicted gene, 31508	11046	0.17
chr5_93282543_93282755	0.21	Ccng2	cyclin G2	13941	0.18
chr19_4623588_4623859	0.21	Mir6986	microRNA 6986	232	0.84
chr9_46230822_46231218	0.21	Apoa1	apolipoprotein A-I	2299	0.14
chr16_91379054_91379459	0.21	Ifnar2	interferon (alpha and beta) receptor 2	6357	0.12
chr19_16437834_16438025	0.20	Gna14	guanine nucleotide binding protein, alpha 14	1371	0.4
chr3_96451459_96451723	0.20	BC107364	cDNA sequence BC107364	715	0.31
chr3_96458907_96459172	0.20	Gm10685	predicted gene 10685	830	0.26
chr8_41041775_41041987	0.20	Mtus1	mitochondrial tumor suppressor 1	15	0.97
chr8_46386589_46386784	0.19	Gm45253	predicted gene 45253	798	0.57
chr19_61049084_61049293	0.19	Gm22520	predicted gene, 22520	35643	0.14
chr3_96402109_96402496	0.19	Gm26654	predicted gene, 26654	79	0.72
chr11_75196330_75196483	0.19	Rtn4rl1	reticulon 4 receptor-like 1	2623	0.15
chr2_36092832_36093004	0.18	Lhx6	LIM homeobox protein 6	1355	0.33
chr7_19955922_19956099	0.18	Rpl7a-ps8	ribosomal protein L7A, pseudogene 8	2227	0.14
chr14_31427037_31427204	0.18	Sh3bp5	SH3-domain binding protein 5 (BTK-associated)	8945	0.15
chr1_153900403_153900624	0.18	Glul	glutamate-ammonia ligase (glutamine synthetase)	72	0.72
chr9_48755281_48755902	0.17	Zbtb16	zinc finger and BTB domain containing 16	80354	0.09
chr18_35831562_35831748	0.17	Gm29417	predicted gene 29417	562	0.55
chr12_104414666_104414826	0.17	Gm24334	predicted gene, 24334	4654	0.15
chr9_31851816_31851990	0.17	Gm31497	predicted gene, 31497	54090	0.1
chr8_126774523_126774869	0.17	Gm45805	predicted gene 45805	16362	0.22
chr4_33284555_33284721	0.17	Pnrc1	proline-rich nuclear receptor coactivator 1	5525	0.18
chr17_25727890_25728059	0.17	Rpusd1	RNA pseudouridylate synthase domain containing 1	242	0.65
chr5_120560470_120560640	0.17	2510016D11Rik	RIKEN cDNA 2510016D11 gene	7516	0.1
chr8_126685189_126685340	0.16	Gm45805	predicted gene 45805	73070	0.1
chr1_39205802_39205953	0.16	Npas2	neuronal PAS domain protein 2	11665	0.18
chr2_94047308_94047485	0.16	Hsd17b12	hydroxysteroid (17-beta) dehydrogenase 12	19073	0.16
chr8_119443770_119443946	0.16	Necab2	N-terminal EF-hand calcium binding protein 2	2861	0.21
chr15_99716487_99716652	0.16	Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)	946	0.3
chr15_79351473_79351624	0.16	Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	3146	0.14
chr13_43493297_43493485	0.16	Gm47683	predicted gene, 47683	6776	0.14
chr8_105759107_105759440	0.16	Gfod2	glucose-fructose oxidoreductase domain containing 2	609	0.58
chr7_81541084_81541411	0.16	Gm37829	predicted gene, 37829	8726	0.1
chr8_13350961_13351112	0.16	Tfdp1	transcription factor Dp 1	11362	0.12
chr14_30916422_30916581	0.16	Itih3	inter-alpha trypsin inhibitor, heavy chain 3	1114	0.35
chr1_39612023_39612366	0.16	Gm5100	predicted gene 5100	14189	0.12
chr14_70338039_70338256	0.15	Slc39a14	solute carrier family 39 (zinc transporter), member 14	3949	0.15
chr9_57283258_57283868	0.15	1700017B05Rik	RIKEN cDNA 1700017B05 gene	20951	0.14
chr9_120731019_120731170	0.15	Gm47064	predicted gene, 47064	20049	0.12
chr10_67536858_67537009	0.15	Egr2	early growth response 2	936	0.47
chr1_134065116_134065322	0.15	Btg2	BTG anti-proliferation factor 2	13901	0.12
chr4_56961559_56961774	0.15	Tmem245	transmembrane protein 245	14229	0.15
chr5_9038233_9038384	0.15	Gm40264	predicted gene, 40264	3184	0.2
chr16_97918472_97918638	0.14	C2cd2	C2 calcium-dependent domain containing 2	4051	0.21
chr1_93686775_93686953	0.14	Bok	BCL2-related ovarian killer	601	0.66
chr3_96646975_96647126	0.14	Itga10	integrin, alpha 10	1466	0.17
chr10_121423941_121424099	0.14	Gm18730	predicted gene, 18730	23307	0.11
chr10_58233103_58233399	0.14	Duxf3	double homeobox family member 3	576	0.63
chr9_62344600_62344925	0.14	Anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	37	0.98
chr7_110853928_110854130	0.14	Lyve1	lymphatic vessel endothelial hyaluronan receptor 1	8924	0.15
chr11_51832795_51832987	0.14	Jade2	jade family PHD finger 2	24234	0.15
chr13_45907083_45907460	0.14	4930453C13Rik	RIKEN cDNA 4930453C13 gene	28769	0.18
chr7_141478122_141478322	0.14	Tspan4	tetraspanin 4	1822	0.13
chr11_81374622_81374773	0.14	4930527B05Rik	RIKEN cDNA 4930527B05 gene	10316	0.3
chr15_82668190_82668753	0.14	Cyp2d35-ps	cytochrome P450, family 2, subfamily d, member 35, pseudogene	13760	0.07
chr8_35290423_35290789	0.14	Gm34597	predicted gene, 34597	45127	0.11
chr8_126656995_126657172	0.13	Irf2bp2	interferon regulatory factor 2 binding protein 2	63097	0.12
chr17_4199793_4199983	0.13	4930548J01Rik	RIKEN cDNA 4930548J01 gene	77775	0.11
chr11_67535494_67535665	0.13	Gas7	growth arrest specific 7	11575	0.23
chr3_36079982_36080141	0.13	Acad9	acyl-Coenzyme A dehydrogenase family, member 9	85	0.95
chr7_24653592_24653770	0.13	Gm4598	predicted gene 4598	7613	0.08
chr2_32259552_32259703	0.13	Uck1	uridine-cytidine kinase 1	6	0.94
chr4_155028352_155028518	0.13	Plch2	phospholipase C, eta 2	9003	0.13
chr8_116185346_116185497	0.13	4930422C21Rik	RIKEN cDNA 4930422C21 gene	1948	0.49
chr15_36476548_36476699	0.13	Ankrd46	ankyrin repeat domain 46	20092	0.13
chr16_24082765_24082916	0.13	Gm46545	predicted gene, 46545	150	0.95
chr4_141536459_141536662	0.13	Spen	spen family transcription repressor	1693	0.27
chr14_30939550_30939725	0.13	Itih1	inter-alpha trypsin inhibitor, heavy chain 1	3640	0.13
chr11_75430733_75430997	0.13	Gm12337	predicted gene 12337	3112	0.11
chr11_101728654_101728805	0.13	Dhx8	DEAH (Asp-Glu-Ala-His) box polypeptide 8	4190	0.16
chr12_37906736_37906912	0.13	Dgkb	diacylglycerol kinase, beta	26108	0.21
chr9_108083457_108083608	0.13	Rnf123	ring finger protein 123	186	0.77
chr2_155272603_155272754	0.13	Map1lc3a	microtubule-associated protein 1 light chain 3 alpha	3619	0.2
chr4_134399064_134399223	0.13	Pafah2	platelet-activating factor acetylhydrolase 2	1672	0.26
chr18_67800429_67800656	0.13	Cep192	centrosomal protein 192	408	0.57
chr4_49501233_49501521	0.13	Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	1743	0.25
chr4_53263517_53263892	0.13	AI427809	expressed sequence AI427809	127	0.96
chr1_138322744_138322953	0.13	Atp6v1g3	ATPase, H+ transporting, lysosomal V1 subunit G3	49110	0.12
chr1_131963395_131963600	0.13	Slc45a3	solute carrier family 45, member 3	530	0.42
chr16_30550091_30550467	0.12	Tmem44	transmembrane protein 44	249	0.93
chr5_9059465_9059641	0.12	Gm40264	predicted gene, 40264	24429	0.13
chr6_48595408_48595586	0.12	Repin1	replication initiator 1	1178	0.2
chr11_70489793_70489955	0.12	Tm4sf5	transmembrane 4 superfamily member 5	15370	0.06
chr15_36933623_36933947	0.12	Gm41300	predicted gene, 41300	2099	0.27
chr18_46713777_46714063	0.12	Cdo1	cysteine dioxygenase 1, cytosolic	14109	0.13
chr8_106936247_106936398	0.12	Sntb2	syntrophin, basic 2	173	0.92
chr5_114581477_114581628	0.12	Fam222a	family with sequence similarity 222, member A	13535	0.15
chr8_35410788_35410939	0.12	Gm45301	predicted gene 45301	1357	0.39
chr17_36019112_36019264	0.12	H2-T24	histocompatibility 2, T region locus 24	1337	0.17
chr12_105546152_105546368	0.12	Gm47796	predicted gene, 47796	15003	0.14
chr15_100682914_100683075	0.12	Cela1	chymotrypsin-like elastase family, member 1	125	0.93
chr1_133307113_133307383	0.12	Golt1a	golgi transport 1A	2552	0.17
chr15_77160485_77160636	0.12	Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	6748	0.15
chr11_109502246_109502399	0.12	Gm22378	predicted gene, 22378	2498	0.21
chr6_72624193_72624362	0.12	Gm15401	predicted gene 15401	5011	0.09
chr8_90371977_90372137	0.12	Tox3	TOX high mobility group box family member 3	23714	0.27
chr8_126694488_126694675	0.12	Gm45805	predicted gene 45805	63753	0.12
chr1_132318004_132318180	0.12	Nuak2	NUAK family, SNF1-like kinase, 2	1927	0.22
chr7_143502927_143503132	0.12	Phlda2	pleckstrin homology like domain, family A, member 2	36	0.96
chr11_58307244_58307445	0.12	Zfp692	zinc finger protein 692	172	0.9
chr3_88406373_88406524	0.12	Pmf1	polyamine-modulated factor 1	3817	0.08
chr1_182648871_182649054	0.12	Gm37516	predicted gene, 37516	30977	0.15
chr5_124636798_124636967	0.12	Atp6v0a2	ATPase, H+ transporting, lysosomal V0 subunit A2	7713	0.14
chr11_101733748_101733899	0.12	Dhx8	DEAH (Asp-Glu-Ala-His) box polypeptide 8	782	0.56
chr7_141628129_141628296	0.11	Mir7063	microRNA 7063	7511	0.13
chr10_22645135_22645353	0.11	Slc2a12	solute carrier family 2 (facilitated glucose transporter), member 12	233	0.94
chr11_62487650_62487823	0.11	Gm12278	predicted gene 12278	4939	0.13
chr1_180227522_180227852	0.11	Psen2	presenilin 2	1881	0.26
chr15_86275887_86276051	0.11	Tbc1d22a	TBC1 domain family, member 22a	40464	0.16
chr1_181210349_181210792	0.11	Wdr26	WD repeat domain 26	856	0.52
chr15_97059709_97059903	0.11	Slc38a4	solute carrier family 38, member 4	3850	0.33
chr10_127903210_127903408	0.11	Sdr9c7	4short chain dehydrogenase/reductase family 9C, member 7	105	0.93
chr5_92110647_92110859	0.11	Gm24931	predicted gene, 24931	7530	0.13
chr13_43525896_43526216	0.11	Gm32939	predicted gene, 32939	4164	0.16
chr2_167944308_167944486	0.11	Ptpn1	protein tyrosine phosphatase, non-receptor type 1	6651	0.19
chr6_38343853_38344004	0.11	Zc3hav1	zinc finger CCCH type, antiviral 1	10345	0.13
chr12_25249300_25249688	0.11	Gm19340	predicted gene, 19340	33101	0.15
chr2_26974148_26974379	0.11	Adamts13	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13	770	0.43
chr14_48138613_48138798	0.11	Gm49310	predicted gene, 49310	4481	0.16
chr15_67020007_67020163	0.11	Gm31342	predicted gene, 31342	19973	0.18
chr12_104798236_104798545	0.11	Clmn	calmin	17519	0.19
chr11_98769689_98769972	0.11	Nr1d1	nuclear receptor subfamily 1, group D, member 1	596	0.57
chr10_95625719_95626123	0.11	Gm33336	predicted gene, 33336	6318	0.14
chr19_43898660_43898822	0.11	Dnmbp	dynamin binding protein	8050	0.14
chr13_63562924_63563160	0.11	Ptch1	patched 1	773	0.56
chr11_4119733_4119903	0.11	Sec14l2	SEC14-like lipid binding 2	987	0.33
chr10_41959970_41960121	0.11	Armc2	armadillo repeat containing 2	16077	0.2
chr8_34147011_34147181	0.11	Leprotl1	leptin receptor overlapping transcript-like 1	63	0.95
chr5_102460519_102460675	0.11	1700013M08Rik	RIKEN cDNA 1700013M08 gene	19399	0.2
chr8_11921702_11921858	0.11	Gm45680	predicted gene 45680	26517	0.14
chr6_72218048_72218558	0.11	Atoh8	atonal bHLH transcription factor 8	16234	0.15
chr10_77551087_77551238	0.11	Itgb2	integrin beta 2	20782	0.1
chr3_104220440_104221564	0.11	Magi3	membrane associated guanylate kinase, WW and PDZ domain containing 3	628	0.6
chr5_33218123_33218481	0.11	Spon2	spondin 2, extracellular matrix protein	107	0.96
chr10_28078586_28078966	0.11	Ptprk	protein tyrosine phosphatase, receptor type, K	3766	0.28
chr4_123589098_123589491	0.11	Macf1	microtubule-actin crosslinking factor 1	16234	0.16
chr15_98591099_98591252	0.10	Gm29331	predicted gene 29331	1185	0.26
chr10_96231610_96231804	0.10	4930459C07Rik	RIKEN cDNA 4930459C07 gene	5500	0.22
chr2_118726808_118726959	0.10	Plcb2	phospholipase C, beta 2	1476	0.29
chr11_118215876_118216042	0.10	Cyth1	cytohesin 1	3066	0.2
chr11_116435092_116435485	0.10	Ubald2	UBA-like domain containing 2	779	0.48
chr2_144182222_144182616	0.10	Gm5535	predicted gene 5535	3333	0.2
chr5_74304899_74305225	0.10	Gm15981	predicted gene 15981	11972	0.16
chr17_5004485_5004673	0.10	Arid1b	AT rich interactive domain 1B (SWI-like)	8150	0.25
chr15_10344412_10344563	0.10	Agxt2	alanine-glyoxylate aminotransferase 2	14045	0.18
chr11_83944358_83944548	0.10	Ddx52	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52	1802	0.33
chr8_22124586_22124925	0.10	Nek5	NIMA (never in mitosis gene a)-related expressed kinase 5	283	0.87
chr15_62063425_62063595	0.10	Pvt1	Pvt1 oncogene	24253	0.23
chr13_32970123_32970274	0.10	Serpinb6b	serine (or cysteine) peptidase inhibitor, clade B, member 6b	1300	0.35
chr16_94545906_94546079	0.10	Vps26c	VPS26 endosomal protein sorting factor C	19162	0.16
chr16_75345372_75345557	0.10	Gm49677	predicted gene, 49677	53810	0.16
chr17_26647402_26647562	0.10	Ergic1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	11459	0.13
chr8_90841291_90841442	0.10	Chd9	chromodomain helicase DNA binding protein 9	8301	0.13
chr19_55754460_55754655	0.10	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box	11712	0.28
chr4_105225983_105226273	0.10	Plpp3	phospholipid phosphatase 3	68781	0.12
chr11_120493774_120493943	0.10	Gm11788	predicted gene 11788	1464	0.16
chr13_32821794_32821951	0.10	Wrnip1	Werner helicase interacting protein 1	1106	0.41
chr9_73050700_73050869	0.10	Rab27a	RAB27A, member RAS oncogene family	5800	0.09
chr3_122462488_122462639	0.10	Gm25153	predicted gene, 25153	2164	0.23
chr2_156190488_156190836	0.10	Phf20	PHD finger protein 20	5804	0.13
chr13_37452717_37452952	0.10	Gm29458	predicted gene 29458	374	0.73
chr14_63133928_63134119	0.10	Ctsb	cathepsin B	1495	0.31
chr8_119426295_119426446	0.10	Osgin1	oxidative stress induced growth inhibitor 1	7754	0.15
chr18_60737126_60737516	0.10	Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	4171	0.18
chr5_138823785_138824155	0.10	Gm5294	predicted gene 5294	3890	0.23
chr9_123153278_123153441	0.10	Clec3b	C-type lectin domain family 3, member b	2413	0.18
chr9_53355672_53355823	0.10	Exph5	exophilin 5	14558	0.16
chr15_85710318_85710476	0.10	Mirlet7b	microRNA let7b	3078	0.17
chr1_74190744_74190929	0.10	Cxcr1	chemokine (C-X-C motif) receptor 1	2399	0.18
chr5_8971094_8971245	0.10	Gm15610	predicted gene 15610	779	0.53
chr2_153214800_153214963	0.10	Tspyl3	TSPY-like 3	10560	0.13
chr9_121388029_121388181	0.10	Trak1	trafficking protein, kinesin binding 1	3856	0.22
chr2_129800360_129800704	0.10	Stk35	serine/threonine kinase 35	15	0.98
chr2_75563293_75563456	0.10	Gm13655	predicted gene 13655	70008	0.08
chr17_56609964_56610227	0.09	Micos13	mitochondrial contact site and cristae organizing system subunit 13	324	0.78

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Gli1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.1	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.0	0.2	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.1	GO:0021593	rhombomere morphogenesis(GO:0021593)
0.0	0.1	GO:1902065	response to L-glutamate(GO:1902065)
0.0	0.1	GO:2000823	regulation of androgen receptor activity(GO:2000823)
0.0	0.1	GO:0061144	alveolar secondary septum development(GO:0061144)
0.0	0.1	GO:0015772	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.1	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.1	GO:0052490	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0	0.1	GO:0045200	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0	0.1	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.2	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.1	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.1	GO:0009436	glyoxylate catabolic process(GO:0009436)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0006216	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0	0.0	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.0	0.1	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857)
0.0	0.1	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0	0.2	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0	0.0	GO:0030070	insulin processing(GO:0030070)
0.0	0.1	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.0	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.0	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.0	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.0	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.1	GO:0035428	hexose transmembrane transport(GO:0035428)
0.0	0.0	GO:0010908	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0	0.0	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.0	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.0	0.0	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0	0.0	GO:0048022	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0	0.1	GO:1904587	glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.0	0.0	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.0	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0	0.0	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.2	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.0	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.0	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.0	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.0	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.1	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.0	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.1	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.0	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.1	GO:0044326	dendritic spine neck(GO:0044326)
0.0	0.0	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.0	0.1	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.0	0.0	GO:1990696	USH2 complex(GO:1990696)
0.0	0.0	GO:0097443	sorting endosome(GO:0097443)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.1	GO:0045503	dynein light chain binding(GO:0045503)
0.2	GO:0004849	uridine kinase activity(GO:0004849)
0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	GO:0035939	microsatellite binding(GO:0035939)
0.1	GO:0034845	4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1	GO:0008515	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.1	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1	GO:0045340	mercury ion binding(GO:0045340)
0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	GO:0019961	interferon binding(GO:0019961)
0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.1	GO:0015288	porin activity(GO:0015288)
0.0	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.0	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.1	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters