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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Gtf2i_Gtf2f1

Z-value: 1.65

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Transcription factors associated with Gtf2i_Gtf2f1

Gene Symbol	Gene ID	Gene Info
Gtf2i Ensembl NCBI MGI UniProt	ENSMUSG00000060261.9	general transcription factor II I
Gtf2f1 Ensembl NCBI MGI UniProt	ENSMUSG00000002658.9	general transcription factor IIF, polypeptide 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr17_57011049_57011224	Gtf2f1	152	0.676024	-0.53	2.8e-01	Click!
chr5_134275072_134275253	Gtf2i	119	0.944439	0.87	2.5e-02	Click!
chr5_134316846_134317005	Gtf2i	2165	0.216462	-0.85	3.4e-02	Click!
chr5_134312196_134312355	Gtf2i	253	0.882059	-0.75	8.7e-02	Click!
chr5_134314206_134314357	Gtf2i	97	0.952486	-0.73	1.0e-01	Click!
chr5_134236577_134236737	Gtf2i	4388	0.144359	0.72	1.1e-01	Click!

Activity of the Gtf2i_Gtf2f1 motif across conditions

Conditions sorted by the z-value of the Gtf2i_Gtf2f1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_27252126_27252620	1.04	Gm44641	predicted gene 44641	197	0.84
chr11_98766772_98767040	0.89	Nr1d1	nuclear receptor subfamily 1, group D, member 1	3520	0.12
chrX_42068446_42068784	0.83	Xiap	X-linked inhibitor of apoptosis	140	0.97
chr11_98767109_98767369	0.77	Nr1d1	nuclear receptor subfamily 1, group D, member 1	3187	0.13
chr1_10156105_10156276	0.68	Arfgef1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	1660	0.36
chr9_35116903_35117294	0.62	St3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	225	0.59
chr17_57199524_57200036	0.62	Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	5603	0.12
chr11_16841273_16841607	0.61	Egfros	epidermal growth factor receptor, opposite strand	10738	0.21
chr7_45705038_45705336	0.60	Dbp	D site albumin promoter binding protein	82	0.89
chr18_81199291_81199673	0.58	4930594M17Rik	RIKEN cDNA 4930594M17 gene	36584	0.17
chr4_141955373_141955574	0.57	Fhad1	forkhead-associated (FHA) phosphopeptide binding domain 1	1279	0.36
chr3_88950162_88950588	0.56	Dap3	death associated protein 3	39	0.75
chr5_3379398_3379549	0.56	Cdk6	cyclin-dependent kinase 6	35161	0.15
chr19_10101442_10101987	0.55	Fads2	fatty acid desaturase 2	32	0.97
chr5_129701203_129701458	0.54	Septin14	septin 14	2929	0.16
chr16_70333428_70333579	0.54	Gbe1	glucan (1,4-alpha-), branching enzyme 1	19369	0.24
chr15_77772952_77773160	0.54	Myh9	myosin, heavy polypeptide 9, non-muscle	3277	0.15
chr11_69416113_69416276	0.53	Kdm6b	KDM1 lysine (K)-specific demethylase 6B	2519	0.13
chr10_8518750_8519222	0.52	Ust	uronyl-2-sulfotransferase	161	0.97
chr10_108391097_108391248	0.52	Gm36283	predicted gene, 36283	26079	0.15
chr6_121171179_121171645	0.51	Pex26	peroxisomal biogenesis factor 26	12255	0.13
chr7_127026907_127027653	0.51	Maz	MYC-associated zinc finger protein (purine-binding transcription factor)	243	0.69
chr4_133753896_133754062	0.50	Arid1a	AT rich interactive domain 1A (SWI-like)	3	0.97
chr13_55211103_55211935	0.49	Nsd1	nuclear receptor-binding SET-domain protein 1	22	0.97
chr1_107645210_107645382	0.49	Serpinb8	serine (or cysteine) peptidase inhibitor, clade B, member 8	39416	0.15
chr19_24017522_24017784	0.48	Gm50305	predicted gene, 50305	12873	0.17
chr14_27325762_27325922	0.48	Arhgef3	Rho guanine nucleotide exchange factor (GEF) 3	10224	0.22
chr1_176874134_176874434	0.48	Gm25993	predicted gene, 25993	5550	0.12
chr4_117981622_117981822	0.48	9530034E10Rik	RIKEN cDNA 9530034E10 gene	6686	0.15
chr11_16902164_16902468	0.47	Egfr	epidermal growth factor receptor	2869	0.27
chr15_58947289_58947444	0.47	Mtss1	MTSS I-BAR domain containing 1	6214	0.14
chr16_91495595_91496056	0.46	Ifnar1	interferon (alpha and beta) receptor 1	3176	0.13
chr2_58765113_58765779	0.46	Upp2	uridine phosphorylase 2	121	0.97
chr15_59481007_59481322	0.46	Nsmce2	NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase	106877	0.06
chr10_80152069_80152378	0.46	Midn	midnolin	985	0.31
chr11_120804472_120804662	0.45	Fasn	fatty acid synthase	4038	0.1
chr11_120812894_120813176	0.45	Fasn	fatty acid synthase	2420	0.14
chr18_35829539_35830125	0.43	Cxxc5	CXXC finger 5	44	0.94
chr18_64999443_64999608	0.43	Gm50368	predicted gene, 50368	1650	0.42
chr9_35045000_35045333	0.43	St3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	10628	0.18
chr11_49695809_49695960	0.43	Gm12192	predicted gene 12192	1996	0.22
chr8_104340179_104340791	0.43	Cmtm3	CKLF-like MARVEL transmembrane domain containing 3	42	0.94
chr11_98795069_98795435	0.42	Msl1	male specific lethal 1	264	0.84
chr7_26833022_26833239	0.40	Cyp2a5	cytochrome P450, family 2, subfamily a, polypeptide 5	2175	0.27
chr13_9764358_9764721	0.40	Zmynd11	zinc finger, MYND domain containing 11	51	0.97
chr2_181042289_181042677	0.39	Chrna4	cholinergic receptor, nicotinic, alpha polypeptide 4	1063	0.42
chr2_58786750_58786901	0.39	Upp2	uridine phosphorylase 2	21500	0.19
chr15_7201002_7201153	0.39	Egflam	EGF-like, fibronectin type III and laminin G domains	21992	0.23
chr11_119856806_119856957	0.38	Rptor	regulatory associated protein of MTOR, complex 1	563	0.72
chr11_59804844_59804999	0.38	Flcn	folliculin	4667	0.11
chr8_24456652_24456803	0.37	Gm44620	predicted gene 44620	9630	0.15
chr6_31148380_31148897	0.37	Gm37728	predicted gene, 37728	1219	0.36
chr9_122713984_122714139	0.37	Gm47136	predicted gene, 47136	272	0.8
chr8_127278652_127278803	0.37	Pard3	par-3 family cell polarity regulator	20858	0.27
chr4_128947381_128947553	0.37	Gm15904	predicted gene 15904	11462	0.15
chr9_74892937_74893252	0.36	Onecut1	one cut domain, family member 1	26610	0.14
chr14_27324759_27324924	0.36	Arhgef3	Rho guanine nucleotide exchange factor (GEF) 3	11225	0.22
chr7_26837189_26837467	0.35	Cyp2a5	cytochrome P450, family 2, subfamily a, polypeptide 5	1125	0.46
chr3_121982194_121982345	0.35	Arhgap29	Rho GTPase activating protein 29	719	0.68
chr6_48445383_48445907	0.35	Zfp467	zinc finger protein 467	48	0.95
chr5_144255609_144256174	0.35	2900089D17Rik	RIKEN cDNA 2900089D17 gene	295	0.71
chr11_16819306_16819457	0.35	Egfros	epidermal growth factor receptor, opposite strand	11321	0.22
chr18_83069323_83069474	0.35	1700095A13Rik	RIKEN cDNA 1700095A13 gene	10443	0.19
chr10_69910495_69910908	0.34	Ank3	ankyrin 3, epithelial	4164	0.35
chr9_8003649_8004083	0.34	Yap1	yes-associated protein 1	91	0.94
chr8_122324060_122324293	0.34	Zfpm1	zinc finger protein, multitype 1	9522	0.13
chrX_13846465_13846885	0.34	Cask	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	60	0.98
chr11_106528042_106528212	0.34	Gm22711	predicted gene, 22711	26882	0.13
chr16_20371861_20372035	0.34	Abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	4694	0.18
chr2_7260084_7260235	0.33	Gm24340	predicted gene, 24340	89938	0.09
chr6_83092517_83092694	0.33	Mir3470a	microRNA 3470a	2218	0.09
chr6_55169879_55170107	0.33	Inmt	indolethylamine N-methyltransferase	5021	0.18
chr15_81836392_81836709	0.33	Gm8444	predicted gene 8444	7163	0.1
chr15_77153726_77153986	0.33	Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	44	0.97
chr11_19016500_19016765	0.33	Meis1	Meis homeobox 1	343	0.83
chr19_40160205_40160356	0.33	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	27006	0.14
chr5_136959042_136959193	0.33	Fis1	fission, mitochondrial 1	2960	0.13
chr4_102635310_102635477	0.33	Pde4b	phosphodiesterase 4B, cAMP specific	45550	0.17
chr6_122826334_122826673	0.33	Foxj2	forkhead box J2	172	0.9
chr6_145866005_145866307	0.32	Bhlhe41	basic helix-loop-helix family, member e41	598	0.7
chr9_30906121_30906748	0.32	Adamts15	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15	3223	0.28
chr19_8228991_8229142	0.32	Slc22a29	solute carrier family 22. member 29	10166	0.16
chr5_129941480_129942081	0.32	Vkorc1l1	vitamin K epoxide reductase complex, subunit 1-like 1	190	0.89
chr11_98747337_98747676	0.32	Thra	thyroid hormone receptor alpha	3273	0.13
chr10_68104594_68104797	0.32	Arid5b	AT rich interactive domain 5B (MRF1-like)	31931	0.18
chr9_74883748_74884038	0.32	Onecut1	one cut domain, family member 1	17409	0.15
chr9_22070765_22071174	0.32	Gm16845	predicted gene, 16845	33	0.67
chr8_105771287_105771438	0.31	Gfod2	glucose-fructose oxidoreductase domain containing 2	12698	0.1
chr15_3281337_3281516	0.31	Selenop	selenoprotein P	9341	0.21
chr5_139364533_139364950	0.31	Mir339	microRNA 339	5004	0.12
chr4_134798939_134799091	0.30	Maco1	macoilin 1	12198	0.18
chr2_70666883_70667034	0.30	Gorasp2	golgi reassembly stacking protein 2	4758	0.18
chr9_106233543_106233694	0.30	Alas1	aminolevulinic acid synthase 1	3466	0.12
chr11_3386939_3387112	0.30	Limk2	LIM motif-containing protein kinase 2	15649	0.11
chrX_74244741_74244892	0.30	Flna	filamin, alpha	1548	0.18
chr15_85538329_85538480	0.30	Gm4825	predicted pseudogene 4825	27592	0.13
chr3_107256063_107256233	0.30	Prok1	prokineticin 1	16441	0.12
chr13_112751899_112752261	0.29	Gm47850	predicted gene, 47850	12768	0.15
chr4_105656165_105656328	0.29	Gm12726	predicted gene 12726	77906	0.11
chr1_45872108_45872259	0.29	Gm5526	predicted pseudogene 5526	14429	0.12
chr8_117201706_117201857	0.29	Gan	giant axonal neuropathy	43644	0.14
chr5_30932575_30932729	0.29	Khk	ketohexokinase	2038	0.15
chr6_145866318_145866575	0.29	Bhlhe41	basic helix-loop-helix family, member e41	888	0.54
chr9_62156150_62156301	0.29	Glce	glucuronyl C5-epimerase	33570	0.14
chr6_125482092_125482283	0.29	Gm28809	predicted gene 28809	243	0.9
chr7_39978543_39978709	0.29	Gm44992	predicted gene 44992	307	0.93
chr9_119983098_119983399	0.29	1700019L13Rik	RIKEN cDNA 1700019L13 gene	31	0.73
chr5_43949049_43949212	0.28	Gm43184	predicted gene 43184	469	0.58
chr7_97842896_97843076	0.28	Pak1	p21 (RAC1) activated kinase 1	51	0.98
chr3_104220440_104221564	0.28	Magi3	membrane associated guanylate kinase, WW and PDZ domain containing 3	628	0.6
chr7_70359312_70359799	0.28	Nr2f2	nuclear receptor subfamily 2, group F, member 2	340	0.81
chr3_89140809_89141081	0.28	Pklr	pyruvate kinase liver and red blood cell	4322	0.08
chr18_75378610_75378854	0.28	Smad7	SMAD family member 7	3818	0.25
chr7_45712198_45712380	0.28	Sphk2	sphingosine kinase 2	1154	0.2
chr6_145855716_145856207	0.28	Gm43909	predicted gene, 43909	7336	0.17
chr7_133710448_133710606	0.28	Uros	uroporphyrinogen III synthase	455	0.64
chr1_51871316_51871480	0.27	Gm28323	predicted gene 28323	8210	0.16
chr12_69822550_69822735	0.27	Gm18030	predicted gene, 18030	2995	0.17
chr19_58975279_58975445	0.27	Eno4	enolase 4	19906	0.17
chr11_100392066_100392243	0.27	Jup	junction plakoglobin	5384	0.08
chr11_16902546_16902715	0.27	Egfr	epidermal growth factor receptor	2555	0.28
chr11_97512026_97512333	0.26	Gm11611	predicted gene 11611	9716	0.13
chr18_5818961_5819357	0.26	Zeb1	zinc finger E-box binding homeobox 1	88078	0.08
chr19_40191699_40191928	0.26	Gm5827	predicted gene 5827	775	0.57
chr7_26313878_26314034	0.26	Gm42375	predicted gene, 42375	6670	0.14
chr12_83947341_83947517	0.26	Gm26571	predicted gene, 26571	3149	0.14
chr8_71516818_71516969	0.26	Plvap	plasmalemma vesicle associated protein	5141	0.08
chr7_65375253_65375421	0.26	Tjp1	tight junction protein 1	4098	0.22
chr15_3275598_3276002	0.26	Selenop	selenoprotein P	3715	0.26
chr5_125478134_125478423	0.26	Gm27551	predicted gene, 27551	1099	0.36
chr4_139614424_139614599	0.26	Aldh4a1	aldehyde dehydrogenase 4 family, member A1	8355	0.14
chr15_96287388_96287856	0.26	Arid2	AT rich interactive domain 2 (ARID, RFX-like)	49	0.97
chr2_163540985_163541167	0.26	Hnf4aos	hepatic nuclear factor 4 alpha, opposite strand	616	0.63
chr1_182100464_182100642	0.26	Srp9	signal recognition particle 9	24184	0.13
chr4_126141128_126141307	0.26	Gm12946	predicted gene 12946	4762	0.12
chr4_129251699_129251979	0.26	C77080	expressed sequence C77080	3396	0.15
chr11_3535115_3535308	0.26	Gm11947	predicted gene 11947	973	0.34
chr10_99226544_99226753	0.25	Gm34574	predicted gene, 34574	2144	0.19
chr18_39362507_39362658	0.25	Arhgap26	Rho GTPase activating protein 26	1	0.98
chr15_82380133_82380458	0.25	Cyp2d22	cytochrome P450, family 2, subfamily d, polypeptide 22	35	0.92
chr13_101839918_101840070	0.25	Gm19108	predicted gene, 19108	2312	0.31
chr18_10093219_10093370	0.25	Rock1	Rho-associated coiled-coil containing protein kinase 1	5086	0.19
chr16_34921418_34921569	0.25	Mylk	myosin, light polypeptide kinase	8849	0.19
chr18_5591844_5592009	0.25	Zeb1	zinc finger E-box binding homeobox 1	14	0.62
chr7_136689615_136689766	0.25	Gm6249	predicted gene 6249	20914	0.22
chr8_89042874_89043785	0.25	Sall1	spalt like transcription factor 1	833	0.68
chr14_27315274_27315446	0.25	Arhgef3	Rho guanine nucleotide exchange factor (GEF) 3	20706	0.2
chr1_190168785_190169209	0.25	Gm28172	predicted gene 28172	327	0.53
chr10_39555812_39556004	0.25	Gm16364	predicted gene 16364	2154	0.3
chr19_9074116_9074267	0.25	Scgb1a1	secretoglobin, family 1A, member 1 (uteroglobin)	13767	0.14
chr17_47299700_47300022	0.25	Trerf1	transcriptional regulating factor 1	5792	0.18
chr8_71498937_71499218	0.25	Gtpbp3	GTP binding protein 3	9618	0.07
chr9_109038478_109038640	0.25	Shisa5	shisa family member 5	6	0.95
chr13_62879517_62879679	0.25	Fbp1	fructose bisphosphatase 1	6840	0.14
chr6_145863616_145863811	0.25	Gm43909	predicted gene, 43909	416	0.78
chr15_101176913_101177067	0.25	Acvr1b	activin A receptor, type 1B	2923	0.15
chr8_36549375_36549526	0.25	Dlc1	deleted in liver cancer 1	27819	0.19
chr13_101739937_101740280	0.25	Gm36638	predicted gene, 36638	11780	0.21
chr1_168431242_168431571	0.25	Pbx1	pre B cell leukemia homeobox 1	98	0.98
chr7_102244007_102244189	0.25	Rhog	ras homolog family member G	5990	0.13
chr10_56377207_56377418	0.25	Gja1	gap junction protein, alpha 1	18	0.98
chr5_113148745_113149067	0.24	Gm42161	predicted gene, 42161	3578	0.14
chr17_46857828_46858121	0.24	Bicral	BRD4 interacting chromatin remodeling complex associated protein like	508	0.74
chr8_84189691_84189963	0.24	Nanos3	nanos C2HC-type zinc finger 3	4610	0.07
chr15_59073137_59073480	0.24	Mtss1	MTSS I-BAR domain containing 1	8681	0.24
chr10_87787661_87787830	0.24	Igf1os	insulin-like growth factor 1, opposite strand	40617	0.16
chr2_85050334_85050532	0.24	Tnks1bp1	tankyrase 1 binding protein 1	27	0.96
chr7_31008253_31008404	0.24	Fam187b	family with sequence similarity 187, member B	26458	0.06
chr4_149150056_149150306	0.24	Rpsa-ps12	ribosomal protein SA, pseudogene 12	6793	0.12
chr3_144199004_144199155	0.24	Gm43445	predicted gene 43445	183	0.95
chr18_64643739_64644174	0.24	Atp8b1	ATPase, class I, type 8B, member 1	16851	0.13
chr17_45557476_45557627	0.24	Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon	1812	0.18
chr11_51632453_51632652	0.24	Rmnd5b	required for meiotic nuclear division 5 homolog B	3095	0.15
chr5_24973360_24973533	0.24	1500035N22Rik	RIKEN cDNA 1500035N22 gene	12396	0.18
chr17_34120395_34120586	0.24	Gm50336	predicted gene, 50336	78	0.47
chr4_16162081_16162259	0.24	Ripk2	receptor (TNFRSF)-interacting serine-threonine kinase 2	1473	0.32
chr6_67267595_67268050	0.23	Serbp1	serpine1 mRNA binding protein 1	492	0.74
chr5_137072037_137072548	0.23	Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	24	0.96
chr5_119625701_119625866	0.23	Gm16063	predicted gene 16063	159	0.92
chr6_83034038_83034205	0.23	Loxl3	lysyl oxidase-like 3	52	0.87
chr4_76449765_76450388	0.23	Ptprd	protein tyrosine phosphatase, receptor type, D	96	0.95
chr4_139580884_139581199	0.23	Iffo2	intermediate filament family orphan 2	6321	0.15
chr4_137820923_137821074	0.23	Alpl	alkaline phosphatase, liver/bone/kidney	24614	0.17
chrX_136172356_136172537	0.23	Tceal8	transcription elongation factor A (SII)-like 8	104	0.94
chr12_103655886_103656171	0.23	Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	1074	0.36
chr7_36697808_36698005	0.23	Tshz3	teashirt zinc finger family member 3	212	0.9
chr6_42349627_42350000	0.23	Zyx	zyxin	15	0.93
chr4_16163923_16164098	0.23	A530072M11Rik	RIKEN cDNA gene A530072M11	100	0.8
chr5_122016911_122017135	0.23	Gm3970	predicted gene 3970	8307	0.16
chr13_114580165_114580482	0.23	Gm25950	predicted gene, 25950	172	0.95
chr1_88316276_88316427	0.23	Trpm8	transient receptor potential cation channel, subfamily M, member 8	2562	0.2
chr12_103996386_103996598	0.23	Gm28577	predicted gene 28577	87	0.94
chr5_146290450_146290749	0.23	Cdk8	cyclin-dependent kinase 8	4311	0.19
chr5_137076386_137076873	0.23	Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	4361	0.13
chr2_166100923_166101091	0.23	Sulf2	sulfatase 2	22888	0.16
chr5_34987481_34987632	0.23	Rgs12	regulator of G-protein signaling 12	1572	0.35
chr6_82041430_82042014	0.23	Eva1a	eva-1 homolog A (C. elegans)	34	0.97
chr9_45041039_45041206	0.23	Mpzl2	myelin protein zero-like 2	945	0.34
chr13_89791634_89791792	0.23	Vcan	versican	49204	0.15
chr11_77776189_77776355	0.22	Myo18a	myosin XVIIIA	993	0.46

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Gtf2i_Gtf2f1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.9	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.2	0.7	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2	0.5	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.1	0.1	GO:0072309	mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309)
0.1	0.9	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.6	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	0.6	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.4	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.1	0.4	GO:0003347	epicardial cell to mesenchymal cell transition(GO:0003347)
0.1	0.2	GO:2000259	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1	0.5	GO:0032776	DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776)
0.1	0.6	GO:0071276	cellular response to cadmium ion(GO:0071276)
0.1	0.3	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.1	0.5	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1	0.3	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.1	0.4	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.1	0.4	GO:0018214	protein carboxylation(GO:0018214)
0.1	0.3	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
0.1	0.1	GO:0006848	pyruvate transport(GO:0006848)
0.1	0.3	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.1	0.3	GO:0061535	glutamate secretion, neurotransmission(GO:0061535)
0.1	0.7	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1	0.4	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.1	0.1	GO:0060375	regulation of mast cell differentiation(GO:0060375)
0.1	0.3	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.1	0.2	GO:0018992	germ-line sex determination(GO:0018992)
0.1	0.2	GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.1	0.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.1	0.3	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.1	0.5	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.1	0.2	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	0.2	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1	0.2	GO:0021648	vestibulocochlear nerve morphogenesis(GO:0021648)
0.1	0.4	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.1	0.3	GO:0071224	cellular response to peptidoglycan(GO:0071224)
0.1	0.5	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1	0.2	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.2	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1	0.4	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1	0.2	GO:0061010	gall bladder development(GO:0061010)
0.1	0.2	GO:0050975	sensory perception of touch(GO:0050975)
0.1	0.2	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	0.2	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1	0.2	GO:0032513	negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.1	0.6	GO:0032986	nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.1	0.4	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.1	0.2	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	0.2	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.1	0.1	GO:1901674	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1	0.2	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1	0.2	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.2	GO:0061356	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
0.1	0.2	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.1	0.2	GO:0046292	formaldehyde metabolic process(GO:0046292)
0.1	0.1	GO:0032741	positive regulation of interleukin-18 production(GO:0032741)
0.1	0.2	GO:0006741	NADP biosynthetic process(GO:0006741)
0.1	0.2	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1	0.1	GO:0097491	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1	0.4	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.1	0.2	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.1	GO:0061625	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.1	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.0	0.1	GO:1902915	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.2	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.2	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.2	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0	0.1	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.2	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.0	0.1	GO:0002434	immune complex clearance(GO:0002434)
0.0	0.3	GO:0043982	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.3	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.1	GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0	0.2	GO:0032264	IMP salvage(GO:0032264)
0.0	0.2	GO:0044838	cell quiescence(GO:0044838)
0.0	0.1	GO:1903660	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.0	GO:0009756	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.0	0.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.1	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.0	0.1	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.0	0.2	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.0	0.2	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.2	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0	0.3	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.1	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.1	GO:0032910	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.0	0.2	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.2	GO:0035627	ceramide transport(GO:0035627)
0.0	0.1	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
0.0	0.6	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0	0.0	GO:0002840	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0	0.1	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.1	GO:0038091	VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.0	0.0	GO:1904139	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0	0.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0009957	epidermal cell fate specification(GO:0009957)
0.0	0.1	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
0.0	0.2	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.0	0.1	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.0	GO:1904238	pericyte cell differentiation(GO:1904238)
0.0	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.2	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.3	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:1903423	positive regulation of synaptic vesicle recycling(GO:1903423)
0.0	0.1	GO:2000909	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.1	GO:1903416	response to glycoside(GO:1903416)
0.0	0.1	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.2	GO:0045925	positive regulation of female receptivity(GO:0045925)
0.0	0.3	GO:0036120	cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0	0.1	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.1	GO:0046084	adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.1	GO:0072262	metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.0	0.1	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.2	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.1	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	0.0	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0	0.3	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.0	0.1	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.0	0.1	GO:1903849	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0	0.5	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.0	0.1	GO:0006868	glutamine transport(GO:0006868)
0.0	0.1	GO:0033227	dsRNA transport(GO:0033227)
0.0	0.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.1	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.0	0.1	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.0	0.2	GO:0060613	fat pad development(GO:0060613)
0.0	0.1	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.3	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.8	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.1	GO:0071305	cellular response to vitamin D(GO:0071305)
0.0	0.1	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.0	0.0	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.3	GO:0060546	negative regulation of necroptotic process(GO:0060546)
0.0	0.1	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.1	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.2	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.0	0.1	GO:0061144	alveolar secondary septum development(GO:0061144)
0.0	0.1	GO:0023021	termination of signal transduction(GO:0023021)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.2	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.1	GO:1903121	regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0061153	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0	0.1	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0	0.3	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0	0.1	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.1	GO:1900368	regulation of RNA interference(GO:1900368)
0.0	0.1	GO:0045950	negative regulation of mitotic recombination(GO:0045950)
0.0	0.1	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0	0.1	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.0	0.1	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	0.0	GO:1904833	positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.0	0.2	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0021590	cerebellum maturation(GO:0021590)
0.0	0.3	GO:1901550	regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.0	0.1	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.1	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.1	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.1	GO:0006742	NADP catabolic process(GO:0006742)
0.0	0.0	GO:1903059	regulation of protein lipidation(GO:1903059)
0.0	0.1	GO:1901529	positive regulation of anion channel activity(GO:1901529)
0.0	0.1	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.6	GO:0001953	negative regulation of cell-matrix adhesion(GO:0001953)
0.0	0.1	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.0	0.1	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.0	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.0	0.2	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.1	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.1	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.0	0.1	GO:0031508	pericentric heterochromatin assembly(GO:0031508)
0.0	0.2	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0	0.1	GO:0060178	regulation of exocyst localization(GO:0060178)
0.0	0.1	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.0	GO:0061551	trigeminal ganglion development(GO:0061551)
0.0	0.0	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.1	GO:0006172	ADP biosynthetic process(GO:0006172)
0.0	0.1	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.0	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.0	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.0	0.1	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.0	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0	0.1	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.1	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.0	0.0	GO:0061184	positive regulation of dermatome development(GO:0061184)
0.0	0.1	GO:0045046	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0	0.1	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.1	GO:0060931	sinoatrial node cell development(GO:0060931)
0.0	0.1	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
0.0	0.4	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.0	0.1	GO:0033625	positive regulation of integrin activation(GO:0033625)
0.0	0.1	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.1	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0	0.1	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0032354	response to follicle-stimulating hormone(GO:0032354) cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0	0.1	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.0	0.1	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0	0.2	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.2	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.0	GO:0003273	cell migration involved in endocardial cushion formation(GO:0003273)
0.0	0.1	GO:0060300	regulation of cytokine activity(GO:0060300)
0.0	0.0	GO:0061205	paramesonephric duct development(GO:0061205)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.0	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.0	0.1	GO:0035754	B cell chemotaxis(GO:0035754)
0.0	0.1	GO:0030578	PML body organization(GO:0030578)
0.0	0.1	GO:0060423	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0	0.1	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.0	GO:0061031	endodermal digestive tract morphogenesis(GO:0061031)
0.0	0.0	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.0	0.1	GO:0051105	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0	0.0	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
0.0	0.0	GO:1903392	negative regulation of adherens junction organization(GO:1903392)
0.0	0.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.0	GO:0098528	skeletal muscle fiber differentiation(GO:0098528)
0.0	0.2	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.0	0.1	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0	0.2	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0	0.1	GO:0010985	negative regulation of lipoprotein particle clearance(GO:0010985)
0.0	0.1	GO:0018002	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0	0.2	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0009838	abscission(GO:0009838)
0.0	0.3	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.0	0.1	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0	0.1	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
0.0	0.1	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.0	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.0	0.1	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.0	0.0	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.0	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.1	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.2	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0048681	negative regulation of axon regeneration(GO:0048681)
0.0	0.1	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.1	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.0	GO:0007403	glial cell fate determination(GO:0007403)
0.0	0.1	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.1	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.2	GO:0060055	angiogenesis involved in wound healing(GO:0060055)
0.0	0.1	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.2	GO:0034331	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0	0.0	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.1	GO:0051683	establishment of Golgi localization(GO:0051683)
0.0	0.1	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.1	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.0	0.0	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.1	GO:0044351	macropinocytosis(GO:0044351)
0.0	0.1	GO:0090187	positive regulation of pancreatic juice secretion(GO:0090187)
0.0	0.2	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.0	GO:1901856	negative regulation of cellular respiration(GO:1901856)
0.0	0.0	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.0	0.1	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.1	GO:0098911	regulation of ventricular cardiac muscle cell action potential(GO:0098911)
0.0	0.1	GO:1901163	regulation of trophoblast cell migration(GO:1901163)
0.0	0.3	GO:0017144	drug metabolic process(GO:0017144)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.1	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.1	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.0	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.1	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.0	0.0	GO:0072202	cell differentiation involved in metanephros development(GO:0072202)
0.0	0.5	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.0	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.0	0.1	GO:0060988	lipid tube assembly(GO:0060988)
0.0	0.1	GO:0015879	carnitine transport(GO:0015879)
0.0	0.0	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532) negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.1	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0	0.1	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.2	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.0	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.0	0.0	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0	0.0	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.0	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.0	0.1	GO:0014744	positive regulation of muscle adaptation(GO:0014744)
0.0	0.0	GO:0090135	actin filament branching(GO:0090135)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.3	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.2	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.1	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.2	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0	0.0	GO:0045583	regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0	0.0	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.2	GO:0000042	protein targeting to Golgi(GO:0000042)
0.0	0.0	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.0	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.0	0.3	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.0	GO:0090031	positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0	0.0	GO:0006059	hexitol metabolic process(GO:0006059)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.0	0.0	GO:1902488	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0	0.1	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.0	GO:2000383	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.0	GO:0009414	response to water deprivation(GO:0009414)
0.0	0.1	GO:0035428	hexose transmembrane transport(GO:0035428)
0.0	0.1	GO:0035584	calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0	0.1	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.0	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.0	GO:0001555	oocyte growth(GO:0001555)
0.0	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.0	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.1	GO:0018119	peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.1	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.0	0.2	GO:0051156	glucose 6-phosphate metabolic process(GO:0051156)
0.0	0.1	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.0	0.1	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.0	0.1	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.0	0.0	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.0	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0	0.0	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.0	0.1	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.0	0.0	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.1	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0071918	urea transmembrane transport(GO:0071918)
0.0	0.0	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.0	GO:0046167	glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0	0.0	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.0	0.1	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0	0.1	GO:1904668	positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0	0.1	GO:0010635	regulation of mitochondrial fusion(GO:0010635)
0.0	0.0	GO:0072092	ureteric bud invasion(GO:0072092)
0.0	0.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.0	GO:0071877	regulation of adrenergic receptor signaling pathway(GO:0071877)
0.0	0.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.0	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.0	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0070970	interleukin-2 secretion(GO:0070970)
0.0	0.1	GO:0002192	IRES-dependent translational initiation(GO:0002192)
0.0	0.0	GO:1903797	positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0	0.2	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0019086	late viral transcription(GO:0019086)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.1	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.0	0.1	GO:0046146	tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.0	GO:0061084	negative regulation of protein refolding(GO:0061084)
0.0	0.0	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0	0.0	GO:1903352	ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0	0.0	GO:0019364	pyridine nucleotide catabolic process(GO:0019364)
0.0	0.1	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.0	0.0	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.0	0.0	GO:1902751	positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0	0.1	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.0	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.0	0.1	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0	0.0	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.3	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.0	0.0	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.0	0.0	GO:0060379	cardiac muscle cell myoblast differentiation(GO:0060379)
0.0	0.2	GO:1990090	response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0	0.1	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.0	0.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.1	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.0	0.0	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0	0.0	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.0	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0	0.0	GO:0014016	neuroblast differentiation(GO:0014016)
0.0	0.1	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.0	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.0	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.0	0.2	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.0	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.0	0.0	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.0	0.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.1	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.0	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.0	GO:0015838	amino-acid betaine transport(GO:0015838)
0.0	0.0	GO:0002578	negative regulation of antigen processing and presentation(GO:0002578) negative regulation of antigen processing and presentation of peptide antigen(GO:0002584)
0.0	0.0	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0	0.0	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.0	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.1	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0	0.0	GO:0002249	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0	0.1	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
0.0	0.1	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.0	GO:0036493	positive regulation of translation in response to stress(GO:0032056) positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0072487	MSL complex(GO:0072487)
0.1	0.6	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.3	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.3	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.2	GO:0097513	myosin II filament(GO:0097513)
0.1	0.8	GO:0071564	npBAF complex(GO:0071564)
0.1	0.2	GO:0042583	chromaffin granule(GO:0042583)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.2	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.3	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.5	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.0	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.1	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.1	GO:0044299	C-fiber(GO:0044299)
0.0	0.1	GO:0000322	storage vacuole(GO:0000322)
0.0	0.5	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.2	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	0.5	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.0	0.2	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.2	GO:0031415	NatA complex(GO:0031415)
0.0	0.1	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.3	GO:0000124	SAGA complex(GO:0000124)
0.0	0.2	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0044308	axonal spine(GO:0044308)
0.0	0.2	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.3	GO:0090544	BAF-type complex(GO:0090544)
0.0	0.1	GO:0031417	NatC complex(GO:0031417)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.2	GO:0001650	fibrillar center(GO:0001650)
0.0	0.1	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.0	GO:0032127	dense core granule membrane(GO:0032127)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.1	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.2	GO:0016600	flotillin complex(GO:0016600)
0.0	0.5	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.2	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.2	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.5	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0071141	SMAD protein complex(GO:0071141)
0.0	1.9	GO:0005923	bicellular tight junction(GO:0005923)
0.0	0.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.1	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.0	0.5	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.2	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.0	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	0.1	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.0	GO:0005827	polar microtubule(GO:0005827)
0.0	0.0	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.0	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:1990696	USH2 complex(GO:1990696)
0.0	0.0	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0	0.2	GO:0031231	intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.2	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.2	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533)
0.0	0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0036449	microtubule minus-end(GO:0036449)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.3	GO:0090568	nuclear transcriptional repressor complex(GO:0090568)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.0	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.0	0.2	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.6	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.0	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.0	GO:0005608	laminin-3 complex(GO:0005608)
0.0	0.0	GO:0005818	aster(GO:0005818)
0.0	0.0	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.0	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.2	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.2	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.2	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:1903293	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.1	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:0033655	host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.0	GO:1990745	EARP complex(GO:1990745)
0.0	0.0	GO:0061574	ASAP complex(GO:0061574)
0.0	0.4	GO:0030173	integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0048408	epidermal growth factor binding(GO:0048408)
0.1	0.9	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.1	0.4	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.1	0.4	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.1	0.6	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.3	GO:0001032	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.1	0.6	GO:0043426	MRF binding(GO:0043426)
0.1	0.3	GO:0016361	activin receptor activity, type I(GO:0016361)
0.1	0.2	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.1	0.2	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.2	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.1	0.5	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.2	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.1	0.1	GO:0017002	activin-activated receptor activity(GO:0017002)
0.1	0.4	GO:0048185	activin binding(GO:0048185)
0.1	0.2	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.2	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.1	0.2	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	0.3	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.1	0.3	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	1.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.2	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
0.1	0.2	GO:0050692	DBD domain binding(GO:0050692)
0.1	0.2	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.1	0.2	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.1	0.3	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.1	0.2	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.1	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.2	GO:0071253	connexin binding(GO:0071253)
0.0	0.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.3	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.2	GO:0035276	ethanol binding(GO:0035276)
0.0	0.3	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0015182	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.2	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.0	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.0	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.5	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.3	GO:1990405	protein antigen binding(GO:1990405)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.0	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.2	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	1.6	GO:0008392	arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.1	GO:0097108	hedgehog family protein binding(GO:0097108)
0.0	0.1	GO:1990188	euchromatin binding(GO:1990188)
0.0	0.2	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.1	GO:0097001	ceramide binding(GO:0097001)
0.0	0.2	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.2	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.3	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.2	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.0	0.4	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	0.1	GO:0038100	nodal binding(GO:0038100)
0.0	0.1	GO:1901612	cardiolipin binding(GO:1901612)
0.0	0.3	GO:0048156	tau protein binding(GO:0048156)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:0048045	4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.0	0.1	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.1	GO:0033142	progesterone receptor binding(GO:0033142)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.3	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.3	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0	0.2	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.1	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.0	0.0	GO:0030519	snoRNP binding(GO:0030519)
0.0	0.0	GO:0004337	geranyltranstransferase activity(GO:0004337)
0.0	0.2	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0019961	interferon binding(GO:0019961)
0.0	0.3	GO:0048038	quinone binding(GO:0048038)
0.0	0.1	GO:0045322	unmethylated CpG binding(GO:0045322)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.2	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.3	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.8	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.2	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.4	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.4	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.2	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	1.0	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.1	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.1	GO:1990190	peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0	0.3	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.2	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.0	GO:0032564	dATP binding(GO:0032564)
0.0	0.1	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.2	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.0	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.2	GO:0015250	water channel activity(GO:0015250)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.3	GO:0030332	cyclin binding(GO:0030332)
0.0	0.0	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.0	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.3	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.5	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.0	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.0	GO:0032557	pyrimidine ribonucleotide binding(GO:0032557)
0.0	0.1	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.1	GO:0001164	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.0	GO:0016015	morphogen activity(GO:0016015)
0.0	0.0	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.9	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.0	GO:0070698	type I activin receptor binding(GO:0070698)
0.0	0.0	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.0	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.2	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.4	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.0	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.1	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.0	GO:0046979	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0	0.1	GO:0036310	annealing helicase activity(GO:0036310)
0.0	0.4	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.2	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.1	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0	0.0	GO:0048030	disaccharide binding(GO:0048030)
0.0	0.1	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.0	GO:0001013	RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0	0.1	GO:0050308	sugar-phosphatase activity(GO:0050308)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.0	0.5	GO:0018722	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.0	0.1	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.0	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.0	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0	0.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.4	GO:0050699	WW domain binding(GO:0050699)
0.0	0.3	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.0	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.0	0.0	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.2	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.1	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.0	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0	0.0	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0	0.0	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.0	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.0	0.2	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:1990459	transferrin receptor binding(GO:1990459)
0.0	0.0	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.2	GO:0030552	cAMP binding(GO:0030552)
0.0	0.0	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.2	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.1	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.1	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.2	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.3	GO:0061650	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	1.4	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	1.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.4	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.8	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.2	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.6	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.3	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.4	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.9	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.4	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.6	PID MYC PATHWAY	C-MYC pathway
0.0	0.0	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.3	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.0	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.5	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.7	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.5	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.5	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.4	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.3	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.2	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.3	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.4	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.1	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.5	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.4	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.0	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.0	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.1	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.2	PID TNF PATHWAY	TNF receptor signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.3	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.1	0.1	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	1.7	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.6	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.6	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.9	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.4	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.6	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.4	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.1	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.5	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.6	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.8	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.3	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.5	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.8	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	1.1	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.0	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.5	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.4	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.1	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.4	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.0	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.0	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.1	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.1	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis

Results for Gtf2i_Gtf2f1

Z-value: 1.65

Motif logo

Transcription factors associated with Gtf2i_Gtf2f1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Gtf2i_Gtf2f1 motif across conditions

Conditions sorted by the z-value of the Gtf2i_Gtf2f1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Gtf2i_Gtf2f1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: