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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Gzf1

Z-value: 1.16

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Transcription factors associated with Gzf1

Gene Symbol	Gene ID	Gene Info
Gzf1 Ensembl NCBI MGI UniProt	ENSMUSG00000027439.9	Gzf1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Gzf1	chr2_148680889_148681282	62	0.967076	-0.82	4.4e-02	Click!
Gzf1	chr2_148693353_148693640	8884	0.145886	0.82	4.7e-02	Click!
Gzf1	chr2_148684656_148684837	134	0.950211	-0.80	5.4e-02	Click!
Gzf1	chr2_148680577_148680742	364	0.837005	0.80	5.8e-02	Click!
Gzf1	chr2_148690686_148690855	6158	0.156373	0.77	7.4e-02	Click!

Activity of the Gzf1 motif across conditions

Conditions sorted by the z-value of the Gzf1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr6_8209868_8210031	0.93	Mios	meiosis regulator for oocyte development	727	0.65
chr4_133451667_133451825	0.88	Tent5b	terminal nucleotidyltransferase 5B	28386	0.1
chr1_88908948_88909111	0.82	Gm4753	predicted gene 4753	23290	0.18
chr7_63921305_63921456	0.81	Klf13	Kruppel-like factor 13	3490	0.16
chr18_38370754_38370932	0.80	Gm4949	predicted gene 4949	10305	0.12
chr8_40922878_40923029	0.67	Pdgfrl	platelet-derived growth factor receptor-like	3259	0.22
chr8_13109068_13109219	0.61	Cul4a	cullin 4A	3207	0.13
chr9_55279082_55279254	0.53	Nrg4	neuregulin 4	4404	0.21
chr2_71256092_71256345	0.52	Dync1i2	dynein cytoplasmic 1 intermediate chain 2	4329	0.23
chr6_116240202_116240376	0.52	Washc2	WASH complex subunit 2`	14317	0.11
chr18_12793031_12793182	0.51	Osbpl1a	oxysterol binding protein-like 1A	25969	0.14
chr2_116983968_116984177	0.49	Gm29340	predicted gene 29340	7644	0.2
chr17_43138649_43138810	0.47	E130008D07Rik	RIKEN cDNA E130008D07 gene	19467	0.26
chr6_91703122_91703273	0.47	Slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6	1540	0.28
chr9_116174746_116175061	0.43	Tgfbr2	transforming growth factor, beta receptor II	362	0.86
chr2_120404351_120404527	0.42	Ganc	glucosidase, alpha; neutral C	101	0.77
chr11_90627862_90628033	0.42	Stxbp4	syntaxin binding protein 4	2970	0.25
chr12_84163524_84163675	0.42	Elmsan1	ELM2 and Myb/SANT-like domain containing 1	3461	0.13
chr6_47792412_47792563	0.42	Rpl31-ps7	ribosomal protein L31, pseudogene 7	6113	0.13
chr2_90561333_90561502	0.41	Ptprj	protein tyrosine phosphatase, receptor type, J	19230	0.2
chr8_25753638_25753875	0.41	Ddhd2	DDHD domain containing 2	524	0.47
chr1_152399824_152400209	0.40	Colgalt2	collagen beta(1-O)galactosyltransferase 2	186	0.95
chr10_77898372_77898523	0.39	Lrrc3	leucine rich repeat containing 3	4089	0.09
chr13_45863946_45864126	0.39	Atxn1	ataxin 1	8252	0.26
chr1_151154930_151155204	0.39	C730036E19Rik	RIKEN cDNA C730036E19 gene	17033	0.11
chr1_67142809_67143033	0.38	Cps1	carbamoyl-phosphate synthetase 1	19895	0.22
chr6_7983342_7983669	0.37	Rnps1-ps	RNA binding protein with serine rich domain 1, pseudogene	122	0.97
chr7_97415846_97416028	0.37	Thrsp	thyroid hormone responsive	1582	0.28
chr4_141546149_141546719	0.37	B330016D10Rik	RIKEN cDNA B330016D10 gene	245	0.89
chrX_140540020_140540246	0.36	Tsc22d3	TSC22 domain family, member 3	2535	0.29
chr4_155848027_155848340	0.36	Dvl1	dishevelled segment polarity protein 1	512	0.52
chr6_6885058_6885209	0.36	Dlx5	distal-less homeobox 5	3048	0.17
chr6_129183742_129184088	0.35	Clec2d	C-type lectin domain family 2, member d	3300	0.15
chr1_155808676_155809110	0.33	Qsox1	quiescin Q6 sulfhydryl oxidase 1	3927	0.15
chr12_26182684_26183045	0.33	Gm29687	predicted gene, 29687	27641	0.15
chr18_12827399_12827550	0.33	Osbpl1a	oxysterol binding protein-like 1A	7567	0.19
chr2_32524561_32524721	0.31	Gm13412	predicted gene 13412	390	0.73
chr15_97048387_97048745	0.31	Slc38a4	solute carrier family 38, member 4	1521	0.52
chrX_140957060_140957250	0.31	Atg4a	autophagy related 4A, cysteine peptidase	205	0.73
chr8_105268773_105269119	0.31	Hsf4	heat shock transcription factor 4	855	0.29
chr16_23056944_23057241	0.30	Kng1	kininogen 1	773	0.39
chr10_82699263_82699421	0.30	Hcfc2	host cell factor C2	131	0.95
chr3_135485099_135485441	0.29	Manba	mannosidase, beta A, lysosomal	341	0.77
chr12_73545525_73545713	0.28	Tmem30b	transmembrane protein 30B	773	0.58
chr19_41418415_41418566	0.28	Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	33388	0.16
chr15_103273560_103273712	0.28	Copz1	coatomer protein complex, subunit zeta 1	724	0.49
chr12_99429400_99429551	0.28	Foxn3	forkhead box N3	16870	0.17
chr19_45805094_45805257	0.28	Kcnip2	Kv channel-interacting protein 2	1601	0.31
chr1_156741988_156742155	0.27	Fam20b	family with sequence similarity 20, member B	22985	0.14
chr7_90158580_90158753	0.27	Picalm	phosphatidylinositol binding clathrin assembly protein	6847	0.12
chr4_135221177_135221356	0.26	Clic4	chloride intracellular channel 4 (mitochondrial)	51548	0.09
chr17_65594339_65595183	0.26	Vapa	vesicle-associated membrane protein, associated protein A	209	0.93
chr7_120176026_120176177	0.26	Anks4b	ankyrin repeat and sterile alpha motif domain containing 4B	2243	0.22
chr3_40746359_40746539	0.26	Hspa4l	heat shock protein 4 like	581	0.72
chr3_138222614_138222780	0.26	Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	1226	0.36
chrX_103288811_103289364	0.26	Gm19200	predicted gene, 19200	117	0.9
chr11_83834151_83834516	0.25	Gm12576	predicted gene 12576	15160	0.12
chr7_99837512_99837672	0.24	Neu3	neuraminidase 3	9175	0.12
chr2_73056230_73056536	0.23	Gm13665	predicted gene 13665	60365	0.09
chr18_44540954_44541143	0.22	Mcc	mutated in colorectal cancers	21532	0.24
chr9_48757158_48757309	0.22	Zbtb16	zinc finger and BTB domain containing 16	78712	0.09
chr16_13276512_13276712	0.22	Mrtfb	myocardin related transcription factor B	11536	0.26
chr15_82244141_82244292	0.22	Cenpm	centromere protein M	116	0.91
chr17_87143110_87143261	0.22	Socs5	suppressor of cytokine signaling 5	35327	0.11
chr2_52476715_52476893	0.21	A430018G15Rik	RIKEN cDNA A430018G15 gene	51792	0.11
chr10_69106905_69107081	0.21	Gm47107	predicted gene, 47107	9127	0.18
chr7_24564744_24564916	0.21	Xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1	739	0.44
chr10_89502299_89502578	0.21	Nr1h4	nuclear receptor subfamily 1, group H, member 4	4211	0.26
chr15_28387409_28387579	0.20	Gm49278	predicted gene, 49278	117697	0.06
chr11_98588166_98588531	0.20	Ormdl3	ORM1-like 3 (S. cerevisiae)	980	0.38
chr19_5294343_5294670	0.20	Sf3b2	splicing factor 3b, subunit 2	128	0.83
chr8_33991786_33992077	0.19	Gm45817	predicted gene 45817	4731	0.17
chr18_16608064_16608271	0.19	Cdh2	cadherin 2	61902	0.14
chr13_8649005_8649216	0.19	Gm48262	predicted gene, 48262	96090	0.07
chr11_120005928_120006087	0.19	Aatk	apoptosis-associated tyrosine kinase	6401	0.11
chr16_14152987_14153329	0.19	Marf1	meiosis regulator and mRNA stability 1	6109	0.14
chr9_74993629_74993780	0.18	Fam214a	family with sequence similarity 214, member A	17593	0.17
chr11_86907144_86907318	0.18	Ypel2	yippee like 2	64793	0.09
chr10_89491324_89491638	0.18	Nr1h4	nuclear receptor subfamily 1, group H, member 4	15168	0.21
chr11_115857814_115857965	0.18	Myo15b	myosin XVB	517	0.62
chr7_72519858_72520162	0.18	Gm37620	predicted gene, 37620	81979	0.09
chr18_39426891_39427064	0.17	Gm15337	predicted gene 15337	37552	0.16
chr15_41162949_41163116	0.17	4930555K19Rik	RIKEN cDNA 4930555K19 gene	10455	0.28
chr9_42138118_42138269	0.17	Gm39321	predicted gene, 39321	3800	0.24
chr1_138044670_138044827	0.17	Gm23782	predicted gene, 23782	56972	0.07
chr17_34911940_34912115	0.17	Ehmt2	euchromatic histone lysine N-methyltransferase 2	1052	0.2
chr14_74741561_74741891	0.17	Esd	esterase D/formylglutathione hydrolase	3220	0.27
chr7_88294280_88294445	0.17	Ctsc	cathepsin C	2490	0.3
chr19_55126042_55126256	0.16	Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	1054	0.54
chr14_41109398_41109729	0.16	Mat1a	methionine adenosyltransferase I, alpha	4182	0.14
chr8_94874425_94874581	0.16	Dok4	docking protein 4	1593	0.24
chr9_48612421_48612590	0.16	Nnmt	nicotinamide N-methyltransferase	7352	0.25
chr15_36275360_36275511	0.16	Rnf19a	ring finger protein 19A	7663	0.12
chr5_8947767_8947928	0.16	Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	10705	0.13
chr1_74061759_74062050	0.16	Tns1	tensin 1	24747	0.17
chr8_69790804_69791266	0.16	Atp13a1	ATPase type 13A1	128	0.51
chr18_40255569_40255732	0.16	Kctd16	potassium channel tetramerisation domain containing 16	1312	0.41
chr5_140794441_140794653	0.16	Gna12	guanine nucleotide binding protein, alpha 12	35610	0.14
chr10_69352418_69352569	0.16	Cdk1	cyclin-dependent kinase 1	410	0.83
chr13_23518940_23519232	0.15	n-TStga1	nuclear encoded tRNA serine 1 (anticodon TGA)	944	0.24
chr5_9101079_9101755	0.15	Tmem243	transmembrane protein 243, mitochondrial	670	0.68
chr4_11239151_11239302	0.14	Ints8	integrator complex subunit 8	3258	0.21
chr15_82793132_82793326	0.14	Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	993	0.37
chr12_82190257_82190917	0.14	Sipa1l1	signal-induced proliferation-associated 1 like 1	20561	0.18
chr8_117725888_117726161	0.13	Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	5088	0.16
chr2_90868308_90868585	0.13	Mtch2	mitochondrial carrier 2	4987	0.12
chr11_101278340_101278806	0.13	Coa3	cytochrome C oxidase assembly factor 3	370	0.44
chr5_44234175_44234326	0.13	Tapt1	transmembrane anterior posterior transformation 1	7624	0.12
chr14_66118821_66119188	0.13	Ephx2	epoxide hydrolase 2, cytoplasmic	5496	0.18
chr10_100589197_100589356	0.13	4930430F08Rik	RIKEN cDNA 4930430F08 gene	28	0.95
chr10_127066593_127066777	0.13	Cdk4	cyclin-dependent kinase 4	609	0.45
chr9_21836570_21836722	0.13	Angptl8	angiopoietin-like 8	1136	0.32
chr10_42254686_42254909	0.12	Foxo3	forkhead box O3	3569	0.32
chr16_72663718_72663897	0.12	Robo1	roundabout guidance receptor 1	603	0.86
chr4_35156757_35157337	0.12	Mob3b	MOB kinase activator 3B	437	0.81
chr11_50037172_50037336	0.12	Rnf130	ring finger protein 130	11906	0.16
chr8_104442536_104442722	0.12	Dync1li2	dynein, cytoplasmic 1 light intermediate chain 2	115	0.77
chr15_85806972_85807337	0.12	Cdpf1	cysteine rich, DPF motif domain containing 1	3936	0.16
chr6_137754996_137755471	0.12	Dera	deoxyribose-phosphate aldolase (putative)	618	0.77
chr7_78910767_78910959	0.12	Isg20	interferon-stimulated protein	2561	0.19
chr4_88034364_88034770	0.12	Gm12631	predicted gene 12631	1066	0.37
chr7_44816822_44816988	0.12	Atf5	activating transcription factor 5	247	0.55
chr10_127888444_127888627	0.12	Rdh7	retinol dehydrogenase 7	205	0.88
chr14_79627613_79627788	0.12	Sugt1	SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)	3061	0.22
chr10_117494201_117494365	0.11	Gm32141	predicted gene, 32141	46790	0.1
chr2_80580802_80580972	0.11	Nckap1	NCK-associated protein 1	377	0.79
chr13_6830007_6830186	0.11	2900024D18Rik	RIKEN cDNA 2900024D18 gene	95755	0.08
chr12_76177934_76178097	0.11	Esr2	estrogen receptor 2 (beta)	756	0.62
chr1_164450614_164451017	0.11	Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	2962	0.2
chr13_93996913_93997222	0.10	Gm47216	predicted gene, 47216	5299	0.2
chr6_74797061_74797232	0.10	Gm22254	predicted gene, 22254	291982	0.01
chr8_123191935_123192230	0.10	Dpep1	dipeptidase 1	1412	0.19
chr4_150660019_150660333	0.10	Slc45a1	solute carrier family 45, member 1	8002	0.19
chr19_4508485_4508947	0.10	Pcx	pyruvate carboxylase	1756	0.26
chr11_78202734_78203046	0.10	Proca1	protein interacting with cyclin A1	8144	0.06
chr18_35134558_35134709	0.10	Ctnna1	catenin (cadherin associated protein), alpha 1	15191	0.19
chr12_4455773_4455955	0.10	Ncoa1	nuclear receptor coactivator 1	21318	0.16
chr7_116039868_116040228	0.09	1110004F10Rik	RIKEN cDNA 1110004F10 gene	336	0.79
chr17_80172841_80173158	0.09	Galm	galactose mutarotase	27847	0.12
chr15_3396811_3397215	0.09	Ghr	growth hormone receptor	74631	0.1
chr5_35028540_35028744	0.09	Rgs12	regulator of G-protein signaling 12	1672	0.27
chr12_59218810_59218961	0.09	Fbxo33	F-box protein 33	84	0.96
chr2_167337145_167337487	0.09	B4galt5	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5	11867	0.18
chr1_180726272_180726587	0.09	Acbd3	acyl-Coenzyme A binding domain containing 3	386	0.77
chr6_54042034_54042185	0.09	Chn2	chimerin 2	2023	0.35
chr16_15637762_15637937	0.09	Prkdc	protein kinase, DNA activated, catalytic polypeptide	17	0.89
chr11_50388012_50388306	0.09	Hnrnph1	heterogeneous nuclear ribonucleoprotein H1	3196	0.18
chr9_50848931_50849288	0.09	Ppp2r1b	protein phosphatase 2, regulatory subunit A, beta	3808	0.18
chr6_82647878_82648248	0.08	Pole4	polymerase (DNA-directed), epsilon 4 (p12 subunit)	4455	0.23
chr4_63236027_63236196	0.08	Col27a1	collagen, type XXVII, alpha 1	1825	0.32
chr4_120387588_120387746	0.08	Scmh1	sex comb on midleg homolog 1	17614	0.22
chr3_110250026_110250177	0.08	C130013H08Rik	RIKEN cDNA C130013H08 gene	86	0.93
chr2_93456519_93456670	0.08	Gm10804	predicted gene 10804	3773	0.2
chr14_73369940_73370196	0.08	Itm2b	integral membrane protein 2B	944	0.58
chr14_66268304_66268471	0.08	Ptk2b	PTK2 protein tyrosine kinase 2 beta	12595	0.17
chr1_36465535_36465686	0.07	Cnnm4	cyclin M4	6010	0.11
chr7_120679030_120679297	0.07	Mosmo	modulator of smoothened	1483	0.21
chr14_74865691_74866187	0.07	Lrch1	leucine-rich repeats and calponin homology (CH) domain containing 1	19316	0.21
chr6_34718943_34719094	0.07	Npn2	neoplastic progression 2	7887	0.14
chr15_39006699_39006925	0.07	Fzd6	frizzled class receptor 6	479	0.5
chr5_90492199_90492408	0.07	Afp	alpha fetoprotein	1065	0.43
chr4_85831605_85831761	0.07	Gm25811	predicted gene, 25811	211811	0.02
chr3_7649491_7649673	0.07	Il7	interleukin 7	35822	0.17
chr6_108282461_108282737	0.07	Itpr1	inositol 1,4,5-trisphosphate receptor 1	29641	0.21
chr5_107961440_107961605	0.07	Dipk1a	divergent protein kinase domain 1A	11476	0.13
chr2_164911992_164912374	0.07	Zfp335	zinc finger protein 335	426	0.6
chr17_56686614_56686939	0.07	Ranbp3	RAN binding protein 3	9959	0.11
chr10_112916902_112917062	0.07	Gm26596	predicted gene, 26596	11519	0.16
chr8_84810711_84810864	0.07	Nfix	nuclear factor I/X	10443	0.08
chr11_106842172_106842332	0.06	Smurf2	SMAD specific E3 ubiquitin protein ligase 2	2954	0.17
chr10_127643746_127644134	0.06	Stat6	signal transducer and activator of transcription 6	938	0.35
chr7_45124707_45124921	0.06	Rps11	ribosomal protein S11	375	0.45
chr4_59000010_59000161	0.06	Dnajc25	DnaJ heat shock protein family (Hsp40) member C25	3087	0.17
chr18_20673992_20674203	0.06	Ttr	transthyretin	8817	0.16
chr19_44544853_44545006	0.06	Sec31b	Sec31 homolog B (S. cerevisiae)	918	0.45
chr8_3392646_3392851	0.06	Arhgef18	rho/rac guanine nucleotide exchange factor (GEF) 18	258	0.91
chr1_34842105_34842416	0.06	Fam168b	family with sequence similarity 168, member B	704	0.58
chr13_13994363_13994818	0.06	B3galnt2	UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2	170	0.92
chr5_32282757_32282925	0.06	Gm15615	predicted gene 15615	29278	0.14
chr17_32787291_32787473	0.05	Zfp871	zinc finger protein 871	165	0.84
chr3_104218844_104219050	0.05	Magi3	membrane associated guanylate kinase, WW and PDZ domain containing 3	1156	0.35
chr2_26118492_26118757	0.05	Nacc2	nucleus accumbens associated 2, BEN and BTB (POZ) domain containing	4159	0.15
chr1_194362178_194362358	0.05	4930503O07Rik	RIKEN cDNA 4930503O07 gene	139509	0.05
chr13_109343509_109343689	0.05	Mir582	microRNA 582	18855	0.28
chr8_120281580_120281753	0.05	Gse1	genetic suppressor element 1, coiled-coil protein	53210	0.11
chr16_70535063_70535483	0.05	Gbe1	glucan (1,4-alpha-), branching enzyme 1	25721	0.23
chr12_55447086_55447286	0.05	Psma6	proteasome subunit alpha 6	39803	0.11
chr12_91709555_91709810	0.05	Ston2	stonin 2	4292	0.19
chr3_50381633_50381790	0.05	Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	10912	0.23
chr9_71163682_71163840	0.05	Gm32511	predicted gene, 32511	33	0.89
chr16_85085948_85086156	0.05	Gm49227	predicted gene, 49227	5941	0.22
chr4_101250409_101250587	0.05	Jak1	Janus kinase 1	14725	0.13
chr2_73910509_73910709	0.05	Atp5g3	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)	150	0.96
chr17_10496047_10496417	0.05	Gm16168	predicted gene 16168	214	0.96
chr15_77330063_77330442	0.04	Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	23248	0.11
chr18_35703072_35703241	0.04	Dnajc18	DnaJ heat shock protein family (Hsp40) member C18	35	0.52
chr19_38364433_38364731	0.04	Gm50155	predicted gene, 50155	20932	0.12
chr17_13654745_13655106	0.04	2700054A10Rik	RIKEN cDNA 2700054A10 gene	13966	0.15
chr14_41120025_41120433	0.04	Sftpa1	surfactant associated protein A1	11553	0.11
chr11_98031142_98031301	0.04	Gm27597	predicted gene, 27597	1808	0.17

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Gzf1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.1	0.2	GO:0051697	protein delipidation(GO:0051697)
0.1	0.3	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.2	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.2	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.1	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.1	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.1	GO:0006068	ethanol catabolic process(GO:0006068)
0.0	0.1	GO:1904179	positive regulation of adipose tissue development(GO:1904179)
0.0	0.1	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354) establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.6	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.0	0.1	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0090166	Golgi disassembly(GO:0090166)
0.0	0.2	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	0.1	GO:0015819	lysine transport(GO:0015819)
0.0	0.1	GO:0060166	olfactory pit development(GO:0060166)
0.0	0.1	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.1	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0	0.2	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0044849	estrous cycle(GO:0044849)
0.0	0.0	GO:0046292	formaldehyde metabolic process(GO:0046292)
0.0	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0010288	response to lead ion(GO:0010288)
0.0	0.1	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.1	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.0	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.2	GO:0034389	lipid particle organization(GO:0034389)
0.0	0.0	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.0	0.1	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0	0.1	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:1904970	brush border assembly(GO:1904970)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.0	GO:0071314	cellular response to cocaine(GO:0071314)
0.0	0.0	GO:1905049	negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0	0.1	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.0	0.0	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.0	0.0	GO:1900211	mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.2	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.1	GO:0035339	SPOTS complex(GO:0035339)
0.0	0.1	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.0	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.1	GO:0031209	SCAR complex(GO:0031209)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.0	GO:0032010	phagolysosome(GO:0032010)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.1	0.3	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.1	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.1	GO:0015189	L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.0	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.2	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.1	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
0.0	0.0	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.4	PID ALK1 PATHWAY	ALK1 signaling events
0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport