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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Hlx

Z-value: 0.65

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Transcription factors associated with Hlx

Gene Symbol	Gene ID	Gene Info
Hlx Ensembl NCBI MGI UniProt	ENSMUSG00000039377.6	Hlx

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Hlx	chr1_184732600_184732772	67	0.962378	-0.78	6.7e-02	Click!
Hlx	chr1_184729358_184729760	2039	0.244262	-0.78	6.8e-02	Click!
Hlx	chr1_184729963_184730114	1560	0.305726	0.74	9.3e-02	Click!
Hlx	chr1_184733359_184733533	827	0.525337	-0.61	2.0e-01	Click!
Hlx	chr1_184734331_184734518	1805	0.253962	0.56	2.5e-01	Click!

Activity of the Hlx motif across conditions

Conditions sorted by the z-value of the Hlx motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_90338896_90339063	0.93	Ankrd17	ankyrin repeat domain 17	764	0.67
chr9_106264996_106265377	0.60	Poc1a	POC1 centriolar protein A	15875	0.1
chr10_89573725_89573906	0.54	Gm48087	predicted gene, 48087	18096	0.17
chr1_195223205_195223404	0.48	Gm37887	predicted gene, 37887	538	0.73
chr17_64607771_64607970	0.48	Man2a1	mannosidase 2, alpha 1	7134	0.26
chr9_15301981_15302132	0.46	4931406C07Rik	RIKEN cDNA 4931406C07 gene	500	0.46
chr16_24449611_24449762	0.45	Lpp	LIM domain containing preferred translocation partner in lipoma	1595	0.42
chr5_86919547_86919811	0.44	Gm25211	predicted gene, 25211	3357	0.13
chr2_34049474_34049625	0.43	C230014O12Rik	RIKEN cDNA C230014O12 gene	58180	0.11
chr8_61563294_61563445	0.40	Palld	palladin, cytoskeletal associated protein	27770	0.22
chrX_38400123_38400274	0.39	Gm4853	predicted pseudogene 4853	3263	0.22
chr11_28696253_28696446	0.38	2810471M01Rik	RIKEN cDNA 2810471M01 gene	14785	0.17
chr6_72120521_72121047	0.38	4933431G14Rik	RIKEN cDNA 4933431G14 gene	2156	0.2
chr1_119646750_119646988	0.37	Epb41l5	erythrocyte membrane protein band 4.1 like 5	1748	0.32
chr1_127787130_127787281	0.37	Ccnt2	cyclin T2	9366	0.16
chr16_94606252_94606403	0.36	Gm15971	predicted gene 15971	14050	0.19
chr5_150650487_150650670	0.36	N4bp2l2	NEDD4 binding protein 2-like 2	2317	0.19
chr6_37510078_37510463	0.35	Akr1d1	aldo-keto reductase family 1, member D1	19903	0.21
chr4_123990393_123990580	0.35	Gm12902	predicted gene 12902	64252	0.08
chr2_157367239_157367418	0.34	Manbal	mannosidase, beta A, lysosomal-like	266	0.9
chr6_119380906_119381057	0.34	Adipor2	adiponectin receptor 2	7705	0.21
chr12_70985566_70985717	0.33	Psma3	proteasome subunit alpha 3	1251	0.39
chr14_119831250_119831463	0.33	4930404K13Rik	RIKEN cDNA 4930404K13 gene	32378	0.19
chrX_49489499_49489695	0.33	Arhgap36	Rho GTPase activating protein 36	3922	0.27
chr19_29285240_29285391	0.32	Jak2	Janus kinase 2	32874	0.12
chr7_83634897_83635261	0.32	Gm45838	predicted gene 45838	1708	0.22
chr7_70356055_70356242	0.31	Nr2f2	nuclear receptor subfamily 2, group F, member 2	911	0.45
chr14_79629212_79629374	0.30	Sugt1	SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)	4654	0.19
chr4_32300145_32300312	0.29	Bach2it1	BTB and CNC homology 2, intronic transcript 1	48467	0.14
chr14_45487800_45488006	0.29	Fermt2	fermitin family member 2	3934	0.14
chr6_17059434_17059627	0.29	Gm15473	predicted gene 15473	5466	0.23
chr2_12925309_12925626	0.29	Pter	phosphotriesterase related	1366	0.49
chr12_75472570_75472746	0.28	Gm47690	predicted gene, 47690	36087	0.17
chr7_89401915_89402333	0.28	Tmem135	transmembrane protein 135	2098	0.22
chr4_137313822_137313984	0.28	Gm25772	predicted gene, 25772	11656	0.14
chr19_55111923_55112097	0.27	Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	8919	0.2
chr10_125785978_125786129	0.27	Lrig3	leucine-rich repeats and immunoglobulin-like domains 3	180115	0.03
chr13_95326893_95327258	0.26	Zbed3	zinc finger, BED type containing 3	308	0.86
chr6_38794603_38794986	0.24	Hipk2	homeodomain interacting protein kinase 2	23552	0.21
chr11_85131557_85131734	0.24	Usp32	ubiquitin specific peptidase 32	8284	0.14
chr3_138278438_138278607	0.24	Adh1	alcohol dehydrogenase 1 (class I)	871	0.47
chr2_127608341_127608498	0.24	Mrps5	mitochondrial ribosomal protein S5	8386	0.13
chr11_4095549_4095867	0.23	Mtfp1	mitochondrial fission process 1	263	0.83
chr2_166153854_166154005	0.23	Sulf2	sulfatase 2	494	0.79
chr1_21315523_21315674	0.23	Gm21909	predicted gene, 21909	722	0.5
chr12_51274477_51274668	0.23	Rps11-ps4	ribosomal protein S11, pseudogene 4	22915	0.22
chr11_72010467_72010628	0.23	Gm23226	predicted gene, 23226	12208	0.15
chr16_21826703_21826857	0.22	Map3k13	mitogen-activated protein kinase kinase kinase 13	838	0.48
chr10_10426013_10426174	0.22	Adgb	androglobin	3746	0.26
chr10_87040962_87041138	0.22	1700113H08Rik	RIKEN cDNA 1700113H08 gene	16995	0.16
chr2_154875946_154876097	0.22	Eif2s2	eukaryotic translation initiation factor 2, subunit 2 (beta)	16761	0.19
chr8_109803384_109803547	0.22	Ap1g1	adaptor protein complex AP-1, gamma 1 subunit	24559	0.12
chr4_124809297_124809476	0.21	Mtf1	metal response element binding transcription factor 1	6708	0.1
chr11_32651005_32651314	0.21	Fbxw11	F-box and WD-40 domain protein 11	8255	0.23
chr2_144369139_144369688	0.21	Kat14	lysine acetyltransferase 14	414	0.43
chr8_71699244_71699423	0.21	B3gnt3	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	2456	0.13
chr4_109104769_109104920	0.21	Osbpl9	oxysterol binding protein-like 9	3187	0.27
chr19_32778255_32778413	0.21	Pten	phosphatase and tensin homolog	20739	0.22
chr11_35732740_35732891	0.21	Pank3	pantothenate kinase 3	36669	0.14
chr2_103177461_103177622	0.20	Gm13874	predicted gene 13874	246	0.92
chr16_43375815_43375981	0.20	Zbtb20	zinc finger and BTB domain containing 20	11694	0.17
chr2_64026273_64026476	0.20	Fign	fidgetin	71614	0.14
chr2_103790393_103790544	0.20	Caprin1	cell cycle associated protein 1	6076	0.11
chr14_21211171_21211322	0.20	Adk	adenosine kinase	106879	0.06
chr19_20608706_20609243	0.19	Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1	7013	0.22
chr12_33285610_33285770	0.19	Atxn7l1	ataxin 7-like 1	16825	0.2
chr1_88055296_88055515	0.19	Ugt1a10	UDP glycosyltransferase 1 family, polypeptide A10	6	0.94
chr10_8928866_8929030	0.19	Gm48728	predicted gene, 48728	23001	0.15
chr16_37566906_37567176	0.19	Rabl3	RAB, member RAS oncogene family-like 3	3307	0.18
chr18_4929619_4929788	0.18	Svil	supervillin	7977	0.3
chr9_7858246_7858397	0.18	Birc3	baculoviral IAP repeat-containing 3	2005	0.3
chr9_74885383_74885534	0.18	Onecut1	one cut domain, family member 1	18974	0.14
chr2_155136281_155136621	0.18	Itch	itchy, E3 ubiquitin protein ligase	2890	0.22
chr13_48543258_48543458	0.18	Gm37238	predicted gene, 37238	1675	0.18
chr18_64619314_64619465	0.18	Gm6978	predicted gene 6978	6290	0.17
chr17_45570529_45570680	0.18	Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	868	0.38
chr1_13715965_13716146	0.18	Xkr9	X-linked Kx blood group related 9	47284	0.12
chr6_141994065_141994238	0.18	Gm6614	predicted gene 6614	14594	0.21
chr7_3664020_3664377	0.18	Leng1	leukocyte receptor cluster (LRC) member 1	1642	0.13
chr18_33210537_33210688	0.17	Stard4	StAR-related lipid transfer (START) domain containing 4	3154	0.37
chr12_57515437_57515691	0.17	Gm2568	predicted gene 2568	5060	0.18
chr3_63961910_63962265	0.17	Gm26850	predicted gene, 26850	1546	0.27
chr14_25538345_25538496	0.17	Mir3075	microRNA 3075	3981	0.21
chr8_111533821_111533983	0.17	Znrf1	zinc and ring finger 1	2195	0.29
chr2_5939653_5939804	0.16	Dhtkd1	dehydrogenase E1 and transketolase domain containing 1	3015	0.22
chr2_18587299_18587467	0.16	Gm13353	predicted gene 13353	19257	0.18
chr16_17069481_17069751	0.16	Ypel1	yippee like 1	80	0.93
chr3_138223407_138223558	0.16	Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	2011	0.23
chr5_91204972_91205145	0.16	Gm23092	predicted gene, 23092	12946	0.21
chr5_88581999_88582150	0.16	Rufy3	RUN and FYVE domain containing 3	1439	0.36
chr16_24477436_24477695	0.16	Lpp	LIM domain containing preferred translocation partner in lipoma	29474	0.18
chr1_67150788_67150939	0.16	Cps1	carbamoyl-phosphate synthetase 1	27837	0.2
chr12_16586341_16586492	0.15	Lpin1	lipin 1	3304	0.3
chr6_51269674_51270293	0.15	Mir148a	microRNA 148a	73	0.98
chr7_100610040_100610203	0.15	Mrpl48	mitochondrial ribosomal protein L48	1820	0.19
chr2_173741924_173742368	0.15	Vapb	vesicle-associated membrane protein, associated protein B and C	4635	0.17
chr14_47295088_47295256	0.15	Mapk1ip1l	mitogen-activated protein kinase 1 interacting protein 1-like	3094	0.11
chr7_123642615_123642780	0.15	Zkscan2	zinc finger with KRAB and SCAN domains 2	142248	0.04
chr5_123975512_123975863	0.15	Hip1r	huntingtin interacting protein 1 related	2059	0.19
chr2_170091915_170092085	0.15	Zfp217	zinc finger protein 217	39220	0.2
chr14_67900348_67900512	0.15	Dock5	dedicator of cytokinesis 5	33002	0.17
chr13_31779124_31779297	0.15	Gm11379	predicted gene 11379	18329	0.16
chr19_36835799_36836029	0.14	Tnks2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	1510	0.42
chr3_60141187_60141605	0.14	Gm24382	predicted gene, 24382	13649	0.22
chr4_76350085_76350300	0.14	Ptprd	protein tyrosine phosphatase, receptor type, D	5949	0.28
chr7_132941355_132941506	0.14	Zranb1	zinc finger, RAN-binding domain containing 1	6738	0.15
chr16_57130407_57130558	0.14	Tomm70a	translocase of outer mitochondrial membrane 70A	7016	0.17
chr4_11614681_11614832	0.14	Gm11832	predicted gene 11832	251	0.9
chr1_119661376_119661532	0.14	Epb41l5	erythrocyte membrane protein band 4.1 like 5	12454	0.16
chr2_114788136_114788290	0.13	Gm13974	predicted gene 13974	65880	0.12
chr9_74328635_74328791	0.13	Gm24141	predicted gene, 24141	33897	0.17
chr18_3465417_3465568	0.13	Gm50088	predicted gene, 50088	1010	0.43
chr6_99189402_99189564	0.13	Foxp1	forkhead box P1	26465	0.25
chr7_140723570_140723813	0.13	Olfr542-ps1	olfactory receptor 542, pseudogene 1	2409	0.15
chr6_50041341_50041531	0.13	Gm3455	predicted gene 3455	9750	0.26
chr7_96957836_96958018	0.13	C230038L03Rik	RIKEN cDNA C230038L03 gene	6041	0.19
chr11_30792834_30792985	0.13	Psme4	proteasome (prosome, macropain) activator subunit 4	18628	0.14
chr4_53134451_53134701	0.13	Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	25319	0.19
chr3_51202400_51202602	0.13	Noct	nocturnin	21946	0.14
chr16_25221904_25222082	0.12	Tprg	transformation related protein 63 regulated	64824	0.14
chr14_20112304_20112464	0.12	Saysd1	SAYSVFN motif domain containing 1	26150	0.14
chr3_138281002_138281176	0.12	Adh1	alcohol dehydrogenase 1 (class I)	3438	0.15
chr4_109655723_109655874	0.12	9630013D21Rik	RIKEN cDNA 9630013D21 gene	1667	0.31
chr1_161244723_161244874	0.12	Prdx6	peroxiredoxin 6	5756	0.18
chr17_10187170_10187336	0.12	Qk	quaking	26321	0.25
chr9_69044250_69044433	0.12	Rora	RAR-related orphan receptor alpha	151200	0.04
chr18_85490238_85490398	0.12	Gm7612	predicted gene 7612	226407	0.02
chr11_115919240_115919538	0.12	Recql5os1	RecQ-like 5, opposite strand 1	5638	0.09
chr11_109771773_109771962	0.12	Gm11684	predicted gene 11684	3381	0.21
chr8_95449738_95450026	0.12	Csnk2a2	casein kinase 2, alpha prime polypeptide	10832	0.12
chr9_103625706_103625857	0.12	Gm38032	predicted gene, 38032	25617	0.16
chr9_63327486_63327998	0.12	Map2k5	mitogen-activated protein kinase kinase 5	24599	0.19
chr1_180179778_180180226	0.12	Coq8a	coenzyme Q8A	1080	0.44
chr2_43592382_43592533	0.12	Kynu	kynureninase	7158	0.3
chr1_162867938_162868165	0.12	Fmo1	flavin containing monooxygenase 1	1441	0.39
chr9_122355767_122356085	0.12	Abhd5	abhydrolase domain containing 5	4137	0.17
chr4_131876493_131876847	0.12	A930004J17Rik	RIKEN cDNA A930004J17 gene	1958	0.19
chr8_93235851_93236023	0.12	Ces1e	carboxylesterase 1E	6318	0.14
chr17_88462554_88462727	0.12	Foxn2	forkhead box N2	21865	0.17
chr2_165869197_165869348	0.12	Zmynd8	zinc finger, MYND-type containing 8	6505	0.15
chr15_53179541_53179708	0.12	Ext1	exostosin glycosyltransferase 1	16631	0.3
chr10_127158373_127158600	0.12	B4galnt1	beta-1,4-N-acetyl-galactosaminyl transferase 1	6739	0.08
chr11_21121403_21121623	0.11	Peli1	pellino 1	13956	0.18
chr10_59149959_59150116	0.11	Septin10	septin 10	28820	0.16
chr4_118031195_118031493	0.11	St3gal3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	538	0.78
chr18_11496730_11496892	0.11	Gm50067	predicted gene, 50067	128104	0.05
chr6_86523276_86523978	0.11	1600020E01Rik	RIKEN cDNA 1600020E01 gene	2620	0.12
chr9_122874871_122875092	0.11	Zfp445	zinc finger protein 445	8975	0.1
chr10_67104058_67104209	0.11	Reep3	receptor accessory protein 3	7188	0.2
chr1_179108579_179108982	0.11	Smyd3	SET and MYND domain containing 3	119435	0.06
chr2_75718851_75719260	0.11	Gm13656	predicted gene 13656	11117	0.12
chr16_37635855_37636049	0.11	Ndufb4	NADH:ubiquinone oxidoreductase subunit B4	13407	0.15
chr10_59277548_59277712	0.11	P4ha1	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide	45666	0.11
chr3_149240098_149240249	0.11	Gm10287	predicted gene 10287	14428	0.2
chr16_84807428_84807749	0.11	Jam2	junction adhesion molecule 2	1819	0.26
chr16_65665507_65665824	0.11	Gm49633	predicted gene, 49633	52246	0.14
chr17_28428613_28428954	0.11	Fkbp5	FK506 binding protein 5	154	0.91
chr12_57537784_57538085	0.11	Foxa1	forkhead box A1	8187	0.15
chr3_19961027_19961202	0.11	Cp	ceruloplasmin	3830	0.21
chr15_3463467_3463618	0.11	Ghr	growth hormone receptor	8102	0.29
chr13_101801879_101802177	0.11	Pik3r1	phosphoinositide-3-kinase regulatory subunit 1	33811	0.15
chr3_84860618_84860912	0.11	Fbxw7	F-box and WD-40 domain protein 7	3380	0.29
chr8_114706794_114706945	0.11	Gm16118	predicted gene 16118	1137	0.54
chr15_3560210_3560361	0.11	Ghr	growth hormone receptor	21557	0.23
chr17_12941646_12941826	0.11	Acat3	acetyl-Coenzyme A acetyltransferase 3	1136	0.27
chr17_88605968_88606119	0.11	Gm9406	predicted gene 9406	2501	0.24
chr19_12638609_12638960	0.10	Glyat	glycine-N-acyltransferase	708	0.5
chr8_3276470_3276698	0.10	Insr	insulin receptor	2967	0.26
chr4_105076264_105076471	0.10	Prkaa2	protein kinase, AMP-activated, alpha 2 catalytic subunit	33523	0.2
chr9_50500490_50500842	0.10	Plet1os	placenta expressed transcript 1, opposite strand	4139	0.14
chr10_10843070_10843258	0.10	4930567K20Rik	RIKEN cDNA 4930567K20 gene	92084	0.07
chr19_55560363_55560546	0.10	Vti1a	vesicle transport through interaction with t-SNAREs 1A	179440	0.03
chr18_51164059_51164479	0.10	Prr16	proline rich 16	46531	0.18
chr13_117679367_117679569	0.10	4933413L06Rik	RIKEN cDNA 4933413L06 gene	40519	0.2
chr11_74924478_74924629	0.10	Srr	serine racemase	1105	0.27
chr3_145762528_145762679	0.10	Ddah1	dimethylarginine dimethylaminohydrolase 1	1855	0.37
chr7_99974308_99974843	0.10	Rnf169	ring finger protein 169	5873	0.14
chr2_174774160_174774316	0.10	Edn3	endothelin 3	4316	0.25
chr5_96206945_96207101	0.10	Mrpl1	mitochondrial ribosomal protein L1	2470	0.32
chr19_47436846_47437016	0.10	Sh3pxd2a	SH3 and PX domains 2A	26572	0.17
chr8_69545222_69545373	0.10	Rps7-ps1	ribosomal protein S7, pseudogene 1	4340	0.17
chr9_74963277_74963428	0.10	Fam214a	family with sequence similarity 214, member A	10280	0.2
chr2_3760026_3760210	0.10	Gm13185	predicted gene 13185	4941	0.2
chr6_94358809_94358972	0.10	Gm19908	predicted gene, 19908	9356	0.21
chr6_58611375_58611579	0.10	Abcg2	ATP binding cassette subfamily G member 2 (Junior blood group)	14806	0.19
chr5_106573383_106573688	0.10	Gm28050	predicted gene, 28050	1180	0.32
chr2_135799055_135799206	0.09	Plcb4	phospholipase C, beta 4	6418	0.23
chr2_119662546_119662712	0.09	Ndufaf1	NADH:ubiquinone oxidoreductase complex assembly factor 1	169	0.9
chr3_87907622_87908270	0.09	Hdgf	heparin binding growth factor	412	0.71
chr11_4832480_4832698	0.09	Nf2	neurofibromin 2	544	0.74
chr1_181842789_181842980	0.09	Lbr	lamin B receptor	25	0.96
chr16_26669241_26669605	0.09	Il1rap	interleukin 1 receptor accessory protein	45267	0.18
chr9_108687622_108687990	0.09	Prkar2a	protein kinase, cAMP dependent regulatory, type II alpha	1508	0.24
chr7_30967090_30967447	0.09	Lsr	lipolysis stimulated lipoprotein receptor	6054	0.07
chr15_51865415_51865710	0.09	Eif3h	eukaryotic translation initiation factor 3, subunit H	39	0.97
chr3_79518695_79518990	0.09	Fnip2	folliculin interacting protein 2	3590	0.21
chr7_19119331_19119555	0.09	Fbxo46	F-box protein 46	416	0.59
chr6_129228000_129228171	0.09	2310001H17Rik	RIKEN cDNA 2310001H17 gene	5889	0.13
chr18_5013827_5013978	0.09	Svil	supervillin	18966	0.27
chr10_24362567_24362800	0.09	Gm15271	predicted gene 15271	84807	0.08

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hlx

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1	0.2	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	0.2	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.1	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.1	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.1	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0	0.1	GO:0030638	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.1	GO:0072361	regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0	0.2	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.0	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.1	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.0	0.1	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.0	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.0	0.0	GO:0052422	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.1	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0	0.1	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0032741	positive regulation of interleukin-18 production(GO:0032741)
0.0	0.0	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.1	GO:0061042	vascular wound healing(GO:0061042)
0.0	0.0	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.0	0.0	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.0	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.0	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0097451	glial limiting end-foot(GO:0097451)
0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	GO:0005642	annulate lamellae(GO:0005642)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1	0.2	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.1	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.0	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.0	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0035671	enone reductase activity(GO:0035671)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.0	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.0	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.0	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0	0.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.1	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation