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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Hlx

Z-value: 0.65

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Transcription factors associated with Hlx

Gene Symbol	Gene ID	Gene Info
Hlx Ensembl NCBI MGI UniProt	ENSMUSG00000039377.6	H2.0-like homeobox

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr1_184732600_184732772	Hlx	67	0.962378	-0.78	6.7e-02	Click!
chr1_184729358_184729760	Hlx	2039	0.244262	-0.78	6.8e-02	Click!
chr1_184729963_184730114	Hlx	1560	0.305726	0.74	9.3e-02	Click!
chr1_184733359_184733533	Hlx	827	0.525337	-0.61	2.0e-01	Click!
chr1_184734331_184734518	Hlx	1805	0.253962	0.56	2.5e-01	Click!

Activity of the Hlx motif across conditions

Conditions sorted by the z-value of the Hlx motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_90338896_90339063	0.93	Ankrd17	ankyrin repeat domain 17	764	0.67
chr9_106264996_106265377	0.60	Poc1a	POC1 centriolar protein A	15875	0.1
chr10_89573725_89573906	0.54	Gm48087	predicted gene, 48087	18096	0.17
chr1_195223205_195223404	0.48	Gm37887	predicted gene, 37887	538	0.73
chr17_64607771_64607970	0.48	Man2a1	mannosidase 2, alpha 1	7134	0.26
chr9_15301981_15302132	0.46	4931406C07Rik	RIKEN cDNA 4931406C07 gene	500	0.46
chr16_24449611_24449762	0.45	Lpp	LIM domain containing preferred translocation partner in lipoma	1595	0.42
chr5_86919547_86919811	0.44	Gm25211	predicted gene, 25211	3357	0.13
chr2_34049474_34049625	0.43	C230014O12Rik	RIKEN cDNA C230014O12 gene	58180	0.11
chr8_61563294_61563445	0.40	Palld	palladin, cytoskeletal associated protein	27770	0.22
chrX_38400123_38400274	0.39	Gm4853	predicted pseudogene 4853	3263	0.22
chr11_28696253_28696446	0.38	2810471M01Rik	RIKEN cDNA 2810471M01 gene	14785	0.17
chr6_72120521_72121047	0.38	4933431G14Rik	RIKEN cDNA 4933431G14 gene	2156	0.2
chr1_119646750_119646988	0.37	Epb41l5	erythrocyte membrane protein band 4.1 like 5	1748	0.32
chr1_127787130_127787281	0.37	Ccnt2	cyclin T2	9366	0.16
chr16_94606252_94606403	0.36	Gm15971	predicted gene 15971	14050	0.19
chr5_150650487_150650670	0.36	N4bp2l2	NEDD4 binding protein 2-like 2	2317	0.19
chr6_37510078_37510463	0.35	Akr1d1	aldo-keto reductase family 1, member D1	19903	0.21
chr4_123990393_123990580	0.35	Gm12902	predicted gene 12902	64252	0.08
chr2_157367239_157367418	0.34	Manbal	mannosidase, beta A, lysosomal-like	266	0.9
chr6_119380906_119381057	0.34	Adipor2	adiponectin receptor 2	7705	0.21
chr12_70985566_70985717	0.33	Psma3	proteasome subunit alpha 3	1251	0.39
chr14_119831250_119831463	0.33	4930404K13Rik	RIKEN cDNA 4930404K13 gene	32378	0.19
chrX_49489499_49489695	0.33	Arhgap36	Rho GTPase activating protein 36	3922	0.27
chr19_29285240_29285391	0.32	Jak2	Janus kinase 2	32874	0.12
chr7_83634897_83635261	0.32	Gm45838	predicted gene 45838	1708	0.22
chr7_70356055_70356242	0.31	Nr2f2	nuclear receptor subfamily 2, group F, member 2	911	0.45
chr14_79629212_79629374	0.30	Sugt1	SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)	4654	0.19
chr4_32300145_32300312	0.29	Bach2it1	BTB and CNC homology 2, intronic transcript 1	48467	0.14
chr14_45487800_45488006	0.29	Fermt2	fermitin family member 2	3934	0.14
chr6_17059434_17059627	0.29	Gm15473	predicted gene 15473	5466	0.23
chr2_12925309_12925626	0.29	Pter	phosphotriesterase related	1366	0.49
chr12_75472570_75472746	0.28	Gm47690	predicted gene, 47690	36087	0.17
chr7_89401915_89402333	0.28	Tmem135	transmembrane protein 135	2098	0.22
chr4_137313822_137313984	0.28	Gm25772	predicted gene, 25772	11656	0.14
chr19_55111923_55112097	0.27	Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	8919	0.2
chr10_125785978_125786129	0.27	Lrig3	leucine-rich repeats and immunoglobulin-like domains 3	180115	0.03
chr13_95326893_95327258	0.26	Zbed3	zinc finger, BED type containing 3	308	0.86
chr6_38794603_38794986	0.24	Hipk2	homeodomain interacting protein kinase 2	23552	0.21
chr11_85131557_85131734	0.24	Usp32	ubiquitin specific peptidase 32	8284	0.14
chr3_138278438_138278607	0.24	Adh1	alcohol dehydrogenase 1 (class I)	871	0.47
chr2_127608341_127608498	0.24	Mrps5	mitochondrial ribosomal protein S5	8386	0.13
chr11_4095549_4095867	0.23	Mtfp1	mitochondrial fission process 1	263	0.83
chr2_166153854_166154005	0.23	Sulf2	sulfatase 2	494	0.79
chr1_21315523_21315674	0.23	Gm21909	predicted gene, 21909	722	0.5
chr12_51274477_51274668	0.23	Rps11-ps4	ribosomal protein S11, pseudogene 4	22915	0.22
chr11_72010467_72010628	0.23	Gm23226	predicted gene, 23226	12208	0.15
chr16_21826703_21826857	0.22	Map3k13	mitogen-activated protein kinase kinase kinase 13	838	0.48
chr10_10426013_10426174	0.22	Adgb	androglobin	3746	0.26
chr10_87040962_87041138	0.22	1700113H08Rik	RIKEN cDNA 1700113H08 gene	16995	0.16
chr2_154875946_154876097	0.22	Eif2s2	eukaryotic translation initiation factor 2, subunit 2 (beta)	16761	0.19
chr8_109803384_109803547	0.22	Ap1g1	adaptor protein complex AP-1, gamma 1 subunit	24559	0.12
chr4_124809297_124809476	0.21	Mtf1	metal response element binding transcription factor 1	6708	0.1
chr11_32651005_32651314	0.21	Fbxw11	F-box and WD-40 domain protein 11	8255	0.23
chr2_144369139_144369688	0.21	Kat14	lysine acetyltransferase 14	414	0.43
chr8_71699244_71699423	0.21	B3gnt3	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	2456	0.13
chr4_109104769_109104920	0.21	Osbpl9	oxysterol binding protein-like 9	3187	0.27
chr19_32778255_32778413	0.21	Pten	phosphatase and tensin homolog	20739	0.22
chr11_35732740_35732891	0.21	Pank3	pantothenate kinase 3	36669	0.14
chr2_103177461_103177622	0.20	Gm13874	predicted gene 13874	246	0.92
chr16_43375815_43375981	0.20	Zbtb20	zinc finger and BTB domain containing 20	11694	0.17
chr2_64026273_64026476	0.20	Fign	fidgetin	71614	0.14
chr2_103790393_103790544	0.20	Caprin1	cell cycle associated protein 1	6076	0.11
chr14_21211171_21211322	0.20	Adk	adenosine kinase	106879	0.06
chr19_20608706_20609243	0.19	Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1	7013	0.22
chr12_33285610_33285770	0.19	Atxn7l1	ataxin 7-like 1	16825	0.2
chr1_88055296_88055515	0.19	Ugt1a10	UDP glycosyltransferase 1 family, polypeptide A10	6	0.94
chr10_8928866_8929030	0.19	Gm48728	predicted gene, 48728	23001	0.15
chr16_37566906_37567176	0.19	Rabl3	RAB, member RAS oncogene family-like 3	3307	0.18
chr18_4929619_4929788	0.18	Svil	supervillin	7977	0.3
chr9_7858246_7858397	0.18	Birc3	baculoviral IAP repeat-containing 3	2005	0.3
chr9_74885383_74885534	0.18	Onecut1	one cut domain, family member 1	18974	0.14
chr2_155136281_155136621	0.18	Itch	itchy, E3 ubiquitin protein ligase	2890	0.22
chr13_48543258_48543458	0.18	Gm37238	predicted gene, 37238	1675	0.18
chr18_64619314_64619465	0.18	Gm6978	predicted gene 6978	6290	0.17
chr17_45570529_45570680	0.18	Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	868	0.38
chr1_13715965_13716146	0.18	Xkr9	X-linked Kx blood group related 9	47284	0.12
chr6_141994065_141994238	0.18	Gm6614	predicted gene 6614	14594	0.21
chr7_3664020_3664377	0.18	Leng1	leukocyte receptor cluster (LRC) member 1	1642	0.13
chr18_33210537_33210688	0.17	Stard4	StAR-related lipid transfer (START) domain containing 4	3154	0.37
chr12_57515437_57515691	0.17	Gm2568	predicted gene 2568	5060	0.18
chr3_63961910_63962265	0.17	Gm26850	predicted gene, 26850	1546	0.27
chr14_25538345_25538496	0.17	Mir3075	microRNA 3075	3981	0.21
chr8_111533821_111533983	0.17	Znrf1	zinc and ring finger 1	2195	0.29
chr2_5939653_5939804	0.16	Dhtkd1	dehydrogenase E1 and transketolase domain containing 1	3015	0.22
chr2_18587299_18587467	0.16	Gm13353	predicted gene 13353	19257	0.18
chr16_17069481_17069751	0.16	Ypel1	yippee like 1	80	0.93
chr3_138223407_138223558	0.16	Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	2011	0.23
chr5_91204972_91205145	0.16	Gm23092	predicted gene, 23092	12946	0.21
chr5_88581999_88582150	0.16	Rufy3	RUN and FYVE domain containing 3	1439	0.36
chr16_24477436_24477695	0.16	Lpp	LIM domain containing preferred translocation partner in lipoma	29474	0.18
chr1_67150788_67150939	0.16	Cps1	carbamoyl-phosphate synthetase 1	27837	0.2
chr12_16586341_16586492	0.15	Lpin1	lipin 1	3304	0.3
chr6_51269674_51270293	0.15	Mir148a	microRNA 148a	73	0.98
chr7_100610040_100610203	0.15	Mrpl48	mitochondrial ribosomal protein L48	1820	0.19
chr2_173741924_173742368	0.15	Vapb	vesicle-associated membrane protein, associated protein B and C	4635	0.17
chr14_47295088_47295256	0.15	Mapk1ip1l	mitogen-activated protein kinase 1 interacting protein 1-like	3094	0.11
chr7_123642615_123642780	0.15	Zkscan2	zinc finger with KRAB and SCAN domains 2	142248	0.04
chr5_123975512_123975863	0.15	Hip1r	huntingtin interacting protein 1 related	2059	0.19
chr2_170091915_170092085	0.15	Zfp217	zinc finger protein 217	39220	0.2
chr14_67900348_67900512	0.15	Dock5	dedicator of cytokinesis 5	33002	0.17
chr13_31779124_31779297	0.15	Gm11379	predicted gene 11379	18329	0.16
chr19_36835799_36836029	0.14	Tnks2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	1510	0.42
chr3_60141187_60141605	0.14	Gm24382	predicted gene, 24382	13649	0.22
chr4_76350085_76350300	0.14	Ptprd	protein tyrosine phosphatase, receptor type, D	5949	0.28
chr7_132941355_132941506	0.14	Zranb1	zinc finger, RAN-binding domain containing 1	6738	0.15
chr16_57130407_57130558	0.14	Tomm70a	translocase of outer mitochondrial membrane 70A	7016	0.17
chr4_11614681_11614832	0.14	Gm11832	predicted gene 11832	251	0.9
chr1_119661376_119661532	0.14	Epb41l5	erythrocyte membrane protein band 4.1 like 5	12454	0.16
chr2_114788136_114788290	0.13	Gm13974	predicted gene 13974	65880	0.12
chr9_74328635_74328791	0.13	Gm24141	predicted gene, 24141	33897	0.17
chr18_3465417_3465568	0.13	Gm50088	predicted gene, 50088	1010	0.43
chr6_99189402_99189564	0.13	Foxp1	forkhead box P1	26465	0.25
chr7_140723570_140723813	0.13	Olfr542-ps1	olfactory receptor 542, pseudogene 1	2409	0.15
chr6_50041341_50041531	0.13	Gm3455	predicted gene 3455	9750	0.26
chr7_96957836_96958018	0.13	C230038L03Rik	RIKEN cDNA C230038L03 gene	6041	0.19
chr11_30792834_30792985	0.13	Psme4	proteasome (prosome, macropain) activator subunit 4	18628	0.14
chr4_53134451_53134701	0.13	Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	25319	0.19
chr3_51202400_51202602	0.13	Noct	nocturnin	21946	0.14
chr16_25221904_25222082	0.12	Tprg	transformation related protein 63 regulated	64824	0.14
chr14_20112304_20112464	0.12	Saysd1	SAYSVFN motif domain containing 1	26150	0.14
chr3_138281002_138281176	0.12	Adh1	alcohol dehydrogenase 1 (class I)	3438	0.15
chr4_109655723_109655874	0.12	9630013D21Rik	RIKEN cDNA 9630013D21 gene	1667	0.31
chr1_161244723_161244874	0.12	Prdx6	peroxiredoxin 6	5756	0.18
chr17_10187170_10187336	0.12	Qk	quaking	26321	0.25
chr9_69044250_69044433	0.12	Rora	RAR-related orphan receptor alpha	151200	0.04
chr18_85490238_85490398	0.12	Gm7612	predicted gene 7612	226407	0.02
chr11_115919240_115919538	0.12	Recql5os1	RecQ-like 5, opposite strand 1	5638	0.09
chr11_109771773_109771962	0.12	Gm11684	predicted gene 11684	3381	0.21
chr8_95449738_95450026	0.12	Csnk2a2	casein kinase 2, alpha prime polypeptide	10832	0.12
chr9_103625706_103625857	0.12	Gm38032	predicted gene, 38032	25617	0.16
chr9_63327486_63327998	0.12	Map2k5	mitogen-activated protein kinase kinase 5	24599	0.19
chr1_180179778_180180226	0.12	Coq8a	coenzyme Q8A	1080	0.44
chr2_43592382_43592533	0.12	Kynu	kynureninase	7158	0.3
chr1_162867938_162868165	0.12	Fmo1	flavin containing monooxygenase 1	1441	0.39
chr9_122355767_122356085	0.12	Abhd5	abhydrolase domain containing 5	4137	0.17
chr4_131876493_131876847	0.12	A930004J17Rik	RIKEN cDNA A930004J17 gene	1958	0.19
chr8_93235851_93236023	0.12	Ces1e	carboxylesterase 1E	6318	0.14
chr17_88462554_88462727	0.12	Foxn2	forkhead box N2	21865	0.17
chr2_165869197_165869348	0.12	Zmynd8	zinc finger, MYND-type containing 8	6505	0.15
chr15_53179541_53179708	0.12	Ext1	exostosin glycosyltransferase 1	16631	0.3
chr10_127158373_127158600	0.12	B4galnt1	beta-1,4-N-acetyl-galactosaminyl transferase 1	6739	0.08
chr11_21121403_21121623	0.11	Peli1	pellino 1	13956	0.18
chr10_59149959_59150116	0.11	Septin10	septin 10	28820	0.16
chr4_118031195_118031493	0.11	St3gal3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	538	0.78
chr18_11496730_11496892	0.11	Gm50067	predicted gene, 50067	128104	0.05
chr6_86523276_86523978	0.11	1600020E01Rik	RIKEN cDNA 1600020E01 gene	2620	0.12
chr9_122874871_122875092	0.11	Zfp445	zinc finger protein 445	8975	0.1
chr10_67104058_67104209	0.11	Reep3	receptor accessory protein 3	7188	0.2
chr1_179108579_179108982	0.11	Smyd3	SET and MYND domain containing 3	119435	0.06
chr2_75718851_75719260	0.11	Gm13656	predicted gene 13656	11117	0.12
chr16_37635855_37636049	0.11	Ndufb4	NADH:ubiquinone oxidoreductase subunit B4	13407	0.15
chr10_59277548_59277712	0.11	P4ha1	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide	45666	0.11
chr3_149240098_149240249	0.11	Gm10287	predicted gene 10287	14428	0.2
chr16_84807428_84807749	0.11	Jam2	junction adhesion molecule 2	1819	0.26
chr16_65665507_65665824	0.11	Gm49633	predicted gene, 49633	52246	0.14
chr17_28428613_28428954	0.11	Fkbp5	FK506 binding protein 5	154	0.91
chr12_57537784_57538085	0.11	Foxa1	forkhead box A1	8187	0.15
chr3_19961027_19961202	0.11	Cp	ceruloplasmin	3830	0.21
chr15_3463467_3463618	0.11	Ghr	growth hormone receptor	8102	0.29
chr13_101801879_101802177	0.11	Pik3r1	phosphoinositide-3-kinase regulatory subunit 1	33811	0.15
chr3_84860618_84860912	0.11	Fbxw7	F-box and WD-40 domain protein 7	3380	0.29
chr8_114706794_114706945	0.11	Gm16118	predicted gene 16118	1137	0.54
chr15_3560210_3560361	0.11	Ghr	growth hormone receptor	21557	0.23
chr17_12941646_12941826	0.11	Acat3	acetyl-Coenzyme A acetyltransferase 3	1136	0.27
chr17_88605968_88606119	0.11	Gm9406	predicted gene 9406	2501	0.24
chr19_12638609_12638960	0.10	Glyat	glycine-N-acyltransferase	708	0.5
chr8_3276470_3276698	0.10	Insr	insulin receptor	2967	0.26
chr4_105076264_105076471	0.10	Prkaa2	protein kinase, AMP-activated, alpha 2 catalytic subunit	33523	0.2
chr9_50500490_50500842	0.10	Plet1os	placenta expressed transcript 1, opposite strand	4139	0.14
chr10_10843070_10843258	0.10	4930567K20Rik	RIKEN cDNA 4930567K20 gene	92084	0.07
chr19_55560363_55560546	0.10	Vti1a	vesicle transport through interaction with t-SNAREs 1A	179440	0.03
chr18_51164059_51164479	0.10	Prr16	proline rich 16	46531	0.18
chr13_117679367_117679569	0.10	4933413L06Rik	RIKEN cDNA 4933413L06 gene	40519	0.2
chr11_74924478_74924629	0.10	Srr	serine racemase	1105	0.27
chr3_145762528_145762679	0.10	Ddah1	dimethylarginine dimethylaminohydrolase 1	1855	0.37
chr7_99974308_99974843	0.10	Rnf169	ring finger protein 169	5873	0.14
chr2_174774160_174774316	0.10	Edn3	endothelin 3	4316	0.25
chr5_96206945_96207101	0.10	Mrpl1	mitochondrial ribosomal protein L1	2470	0.32
chr19_47436846_47437016	0.10	Sh3pxd2a	SH3 and PX domains 2A	26572	0.17
chr8_69545222_69545373	0.10	Rps7-ps1	ribosomal protein S7, pseudogene 1	4340	0.17
chr9_74963277_74963428	0.10	Fam214a	family with sequence similarity 214, member A	10280	0.2
chr2_3760026_3760210	0.10	Gm13185	predicted gene 13185	4941	0.2
chr6_94358809_94358972	0.10	Gm19908	predicted gene, 19908	9356	0.21
chr6_58611375_58611579	0.10	Abcg2	ATP binding cassette subfamily G member 2 (Junior blood group)	14806	0.19
chr5_106573383_106573688	0.10	Gm28050	predicted gene, 28050	1180	0.32
chr2_135799055_135799206	0.09	Plcb4	phospholipase C, beta 4	6418	0.23
chr2_119662546_119662712	0.09	Ndufaf1	NADH:ubiquinone oxidoreductase complex assembly factor 1	169	0.9
chr3_87907622_87908270	0.09	Hdgf	heparin binding growth factor	412	0.71
chr11_4832480_4832698	0.09	Nf2	neurofibromin 2	544	0.74
chr1_181842789_181842980	0.09	Lbr	lamin B receptor	25	0.96
chr16_26669241_26669605	0.09	Il1rap	interleukin 1 receptor accessory protein	45267	0.18
chr9_108687622_108687990	0.09	Prkar2a	protein kinase, cAMP dependent regulatory, type II alpha	1508	0.24
chr7_30967090_30967447	0.09	Lsr	lipolysis stimulated lipoprotein receptor	6054	0.07
chr15_51865415_51865710	0.09	Eif3h	eukaryotic translation initiation factor 3, subunit H	39	0.97
chr3_79518695_79518990	0.09	Fnip2	folliculin interacting protein 2	3590	0.21
chr7_19119331_19119555	0.09	Fbxo46	F-box protein 46	416	0.59
chr6_129228000_129228171	0.09	2310001H17Rik	RIKEN cDNA 2310001H17 gene	5889	0.13
chr18_5013827_5013978	0.09	Svil	supervillin	18966	0.27
chr10_24362567_24362800	0.09	Gm15271	predicted gene 15271	84807	0.08

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hlx

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1	0.2	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	0.2	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.1	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.1	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.1	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0	0.1	GO:0030638	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.1	GO:0072361	regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0	0.2	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.0	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.1	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.0	0.1	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.0	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.0	0.0	GO:0052422	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.1	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0	0.1	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0032741	positive regulation of interleukin-18 production(GO:0032741)
0.0	0.0	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.1	GO:0061042	vascular wound healing(GO:0061042)
0.0	0.0	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.0	0.0	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.0	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.0	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0097451	glial limiting end-foot(GO:0097451)
0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	GO:0005642	annulate lamellae(GO:0005642)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1	0.2	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.1	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.0	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.0	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0035671	enone reductase activity(GO:0035671)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.0	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.0	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.0	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0	0.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.1	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation

Results for Hlx

Z-value: 0.65

Motif logo

Transcription factors associated with Hlx

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Hlx motif across conditions

Conditions sorted by the z-value of the Hlx motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hlx

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: