Project

ENCSR904DTN: DNase-seq of mouse liver in constant darkness

Navigation

Downloads

CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Hmx3

Z-value: 1.24

Motif logo

Transcription factors associated with Hmx3

Gene Symbol	Gene ID	Gene Info
Hmx3 Ensembl NCBI MGI UniProt	ENSMUSG00000040148.5	Hmx3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Hmx3	chr7_131540075_131540234	2713	0.187430	-0.50	3.1e-01	Click!

Activity of the Hmx3 motif across conditions

Conditions sorted by the z-value of the Hmx3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_145056434_145056606	1.54	Gm45181	predicted gene 45181	106476	0.05
chr13_80895235_80895839	1.12	Arrdc3	arrestin domain containing 3	5019	0.18
chr15_27993720_27993871	0.76	Trio	triple functional domain (PTPRF interacting)	1568	0.45
chr8_13160592_13160981	0.74	Lamp1	lysosomal-associated membrane protein 1	1625	0.22
chr2_75202592_75202875	0.68	Gm13653	predicted gene 13653	10456	0.15
chr1_24612849_24613004	0.59	Gm28438	predicted gene 28438	193	0.45
chr7_140112202_140112371	0.57	Paox	polyamine oxidase (exo-N4-amino)	3513	0.11
chr17_81006523_81006701	0.57	Thumpd2	THUMP domain containing 2	58455	0.12
chr9_105878487_105878719	0.56	Col6a5	collagen, type VI, alpha 5	3203	0.27
chr9_102516246_102516552	0.56	Ky	kyphoscoliosis peptidase	4937	0.14
chr1_67124558_67125159	0.51	Cps1	carbamoyl-phosphate synthetase 1	1832	0.42
chr5_74649245_74649406	0.50	Lnx1	ligand of numb-protein X 1	25804	0.15
chr1_154143789_154144011	0.50	A830008E24Rik	RIKEN cDNA A830008E24 gene	25949	0.16
chr11_113725344_113725520	0.49	Cdc42ep4	CDC42 effector protein (Rho GTPase binding) 4	13890	0.12
chr11_16908621_16908873	0.49	Egfr	epidermal growth factor receptor	3562	0.23
chr7_140772355_140773139	0.48	Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	8266	0.09
chr13_85126873_85127061	0.47	Gm4076	predicted gene 4076	547	0.76
chr6_85823511_85823680	0.45	Nat8f5	N-acetyltransferase 8 (GCN5-related) family member 5	2623	0.13
chr18_8939044_8939213	0.45	Gm37148	predicted gene, 37148	10893	0.24
chr8_91333225_91333390	0.45	Fto	fat mass and obesity associated	19693	0.13
chr11_75750659_75750835	0.45	Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	857	0.56
chr6_28681979_28682177	0.44	Snd1	staphylococcal nuclease and tudor domain containing 1	22831	0.21
chr17_4004285_4004445	0.44	4930470H14Rik	RIKEN cDNA 4930470H14 gene	78630	0.11
chr9_116136676_116136901	0.44	Tgfbr2	transforming growth factor, beta receptor II	38477	0.15
chr19_28520868_28521034	0.42	Glis3	GLIS family zinc finger 3	19469	0.24
chr10_108350464_108350766	0.42	Gm23105	predicted gene, 23105	13050	0.19
chrX_84312323_84312721	0.40	Dmd	dystrophin, muscular dystrophy	235873	0.02
chr19_16450910_16451085	0.39	Gna14	guanine nucleotide binding protein, alpha 14	11697	0.17
chr11_16704048_16704199	0.39	Gm25698	predicted gene, 25698	28588	0.15
chr1_9906956_9907361	0.39	Mcmdc2	minichromosome maintenance domain containing 2	1480	0.29
chr13_102858710_102858861	0.39	Mast4	microtubule associated serine/threonine kinase family member 4	47001	0.17
chr5_91200336_91200632	0.39	Gm23092	predicted gene, 23092	17520	0.2
chr4_59292456_59292607	0.39	Susd1	sushi domain containing 1	23435	0.17
chr15_100349593_100349772	0.38	Methig1	methyltransferase hypoxia inducible domain containing 1	3467	0.13
chr10_68137101_68137496	0.38	Arid5b	AT rich interactive domain 5B (MRF1-like)	672	0.78
chr4_80003665_80003823	0.38	Gm11408	predicted gene 11408	170	0.59
chr13_20205112_20205287	0.38	Elmo1	engulfment and cell motility 1	19992	0.25
chr9_56260139_56260312	0.38	Peak1os	pseudopodium-enriched atypical kinase 1, opposite strand	2335	0.21
chr14_22269831_22270192	0.38	Lrmda	leucine rich melanocyte differentiation associated	40154	0.2
chr18_9632745_9632896	0.38	Gm4834	predicted gene 4834	3958	0.16
chr3_69778568_69778734	0.38	Nmd3	NMD3 ribosome export adaptor	32219	0.16
chr1_20481729_20481880	0.38	Gm24162	predicted gene, 24162	36892	0.15
chr4_131939568_131939730	0.38	Epb41	erythrocyte membrane protein band 4.1	2262	0.18
chr2_146577293_146577459	0.37	4933406D12Rik	RIKEN cDNA 4933406D12 gene	34445	0.2
chr1_168502271_168502436	0.37	Mir6348	microRNA 6348	11710	0.27
chr9_55233053_55233204	0.37	Nrg4	neuregulin 4	9333	0.17
chr9_25460856_25461181	0.36	Gm8049	predicted gene 8049	10556	0.2
chr9_112743581_112744166	0.36	Gm24957	predicted gene, 24957	221344	0.02
chr15_54870838_54871021	0.36	Enpp2	ectonucleotide pyrophosphatase/phosphodiesterase 2	8243	0.24
chr15_59391938_59392317	0.35	Nsmce2	NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase	17840	0.18
chr6_35253418_35253775	0.35	1810058I24Rik	RIKEN cDNA 1810058I24 gene	864	0.54
chr12_17601719_17602041	0.35	Gm48313	predicted gene, 48313	3426	0.21
chr19_29968799_29968964	0.35	Il33	interleukin 33	17065	0.16
chr9_59942649_59942840	0.34	Gm20275	predicted gene, 20275	1667	0.26
chrX_136171222_136171400	0.34	Tceal8	transcription elongation factor A (SII)-like 8	890	0.43
chr6_140187005_140187211	0.34	Gm24174	predicted gene, 24174	20463	0.18
chr8_53780941_53781092	0.34	Gm19921	predicted gene, 19921	130723	0.05
chr19_39463095_39463278	0.34	Cyp2c38	cytochrome P450, family 2, subfamily c, polypeptide 38	111	0.98
chr17_62171907_62172058	0.34	Gm49860	predicted gene, 49860	264075	0.02
chr13_34313351_34313741	0.34	Gm47086	predicted gene, 47086	5262	0.21
chr11_116206084_116206272	0.34	Ten1	TEN1 telomerase capping complex subunit	4756	0.1
chr2_159755776_159755955	0.33	Gm11445	predicted gene 11445	22342	0.25
chr19_40191993_40192245	0.33	Gm5827	predicted gene 5827	1081	0.44
chr6_59032854_59033027	0.33	Gm19165	predicted gene, 19165	3949	0.2
chr3_116409014_116409188	0.33	Cdc14a	CDC14 cell division cycle 14A	3613	0.2
chr14_69628830_69628981	0.33	Gm27177	predicted gene 27177	11369	0.11
chr2_125826215_125826366	0.33	Cops2	COP9 signalosome subunit 2	32706	0.15
chr5_96222210_96222544	0.32	Mrpl1	mitochondrial ribosomal protein L1	12233	0.22
chr12_17770698_17770853	0.32	Hpcal1	hippocalcin-like 1	42549	0.14
chr9_74881023_74881569	0.32	Onecut1	one cut domain, family member 1	14812	0.15
chr5_22255477_22255648	0.32	Gm16113	predicted gene 16113	26020	0.16
chr1_89667541_89667692	0.32	4933400F21Rik	RIKEN cDNA 4933400F21 gene	16272	0.23
chr1_60716026_60716187	0.32	Cd28	CD28 antigen	694	0.59
chr18_34868711_34868905	0.32	Egr1	early growth response 1	7601	0.14
chr13_37468607_37468985	0.32	Gm47731	predicted gene, 47731	3242	0.13
chr18_69663255_69663406	0.31	Tcf4	transcription factor 4	6663	0.31
chr1_86700604_86700771	0.31	Dis3l2	DIS3 like 3'-5' exoribonuclease 2	3121	0.19
chr1_52597389_52597548	0.31	Gm5527	predicted gene 5527	12950	0.13
chr11_107452533_107452722	0.31	Pitpnc1	phosphatidylinositol transfer protein, cytoplasmic 1	18072	0.11
chr10_67048205_67048592	0.31	Reep3	receptor accessory protein 3	11076	0.19
chr4_81591457_81591882	0.31	Gm11411	predicted gene 11411	104772	0.07
chr12_80956924_80957266	0.31	Srsf5	serine and arginine-rich splicing factor 5	10719	0.13
chr9_69204954_69205120	0.31	Rora	RAR-related orphan receptor alpha	9496	0.29
chr5_150912926_150913090	0.31	Gm43298	predicted gene 43298	30366	0.16
chr5_75961858_75962064	0.31	Kdr	kinase insert domain protein receptor	16497	0.17
chrX_140387482_140387633	0.30	Frmpd3	FERM and PDZ domain containing 3	5586	0.23
chr5_89416345_89416742	0.30	Gc	vitamin D binding protein	19085	0.24
chr2_173449296_173449460	0.30	Gm14642	predicted gene 14642	54812	0.12
chr2_163661430_163661594	0.30	Pkig	protein kinase inhibitor, gamma	13	0.97
chr4_141955631_141955810	0.29	Fhad1	forkhead-associated (FHA) phosphopeptide binding domain 1	1526	0.3
chr19_26754124_26754675	0.29	Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	799	0.69
chr7_80741087_80741271	0.29	Iqgap1	IQ motif containing GTPase activating protein 1	2701	0.24
chr13_24945328_24945479	0.29	Gpld1	glycosylphosphatidylinositol specific phospholipase D1	2251	0.21
chrX_74270256_74270420	0.29	Rpl10	ribosomal protein L10	474	0.52
chr18_16753631_16753792	0.29	Gm15485	predicted gene 15485	24978	0.2
chr5_90424369_90424630	0.29	Gm43363	predicted gene 43363	27226	0.13
chr11_16908151_16908431	0.29	Egfr	epidermal growth factor receptor	3106	0.25
chr13_58999542_58999699	0.29	Gm34245	predicted gene, 34245	78676	0.08
chr15_91275437_91275588	0.29	CN725425	cDNA sequence CN725425	43934	0.16
chr5_72763116_72763280	0.29	Txk	TXK tyrosine kinase	10421	0.15
chr3_66594684_66595084	0.29	Gm17952	predicted gene, 17952	31333	0.23
chr7_4532478_4532639	0.28	Dnaaf3	dynein, axonemal assembly factor 3	105	0.91
chr2_158859600_158859775	0.28	Dhx35	DEAH (Asp-Glu-Ala-His) box polypeptide 35	9058	0.25
chrX_42148063_42148502	0.28	Stag2	stromal antigen 2	1035	0.46
chr3_65357881_65358061	0.28	Kcnab1	potassium voltage-gated channel, shaker-related subfamily, beta member 1	4204	0.18
chr2_61138777_61138928	0.28	Gm13581	predicted gene 13581	85940	0.09
chr2_122266063_122266214	0.28	Duox2	dual oxidase 2	19431	0.1
chr16_24019943_24020095	0.28	Gm49518	predicted gene, 49518	19887	0.15
chr2_137422722_137422873	0.28	Gm14055	predicted gene 14055	134294	0.05
chr11_109733399_109733703	0.28	Fam20a	family with sequence similarity 20, member A	11272	0.17
chr1_85199249_85199400	0.28	AC123856.1	nuclear antigen Sp100 (Sp100) pseudogene	289	0.46
chr4_138065715_138066098	0.28	Eif4g3	eukaryotic translation initiation factor 4 gamma, 3	61154	0.1
chr9_13681735_13681905	0.27	Maml2	mastermind like transcriptional coactivator 2	19360	0.18
chr2_156585343_156585515	0.27	Gm14168	predicted gene 14168	13637	0.11
chr14_25385763_25386034	0.27	Gm26660	predicted gene, 26660	6289	0.21
chr7_30957359_30958052	0.27	Gm4673	predicted gene 4673	296	0.67
chr18_7847563_7847725	0.27	Gm50027	predicted gene, 50027	2709	0.23
chr17_64643456_64643864	0.27	Man2a1	mannosidase 2, alpha 1	42924	0.17
chr7_126636776_126636927	0.27	Nupr1	nuclear protein transcription regulator 1	5990	0.08
chr3_101509926_101510102	0.27	Atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	67546	0.08
chr1_24613582_24613754	0.27	Gm28437	predicted gene 28437	303	0.51
chr9_107597647_107597798	0.26	Lsmem2	leucine-rich single-pass membrane protein 2	647	0.36
chr6_54199490_54199996	0.26	Gm15526	predicted gene 15526	22060	0.17
chr6_59052402_59052674	0.26	Gm19165	predicted gene, 19165	15649	0.17
chr1_51501426_51501585	0.26	Gm17767	predicted gene, 17767	10824	0.17
chr10_33945506_33945695	0.26	Zup1	zinc finger containing ubiquitin peptidase 1	4260	0.13
chr15_98789109_98789266	0.26	Wnt1	wingless-type MMTV integration site family, member 1	670	0.48
chr12_58323949_58324220	0.26	Clec14a	C-type lectin domain family 14, member a	54794	0.16
chr13_118387400_118387593	0.26	Mrps30	mitochondrial ribosomal protein S30	244	0.86
chr3_61217316_61217479	0.26	Gm37719	predicted gene, 37719	74049	0.1
chr8_36457312_36457463	0.26	Trmt9b	tRNA methyltransferase 9B	161	0.96
chr19_44064101_44064296	0.26	Erlin1	ER lipid raft associated 1	3485	0.17
chr7_28411283_28411456	0.26	Samd4b	sterile alpha motif domain containing 4B	2538	0.12
chr4_149453846_149453997	0.26	Rbp7	retinol binding protein 7, cellular	497	0.65
chr1_24042012_24042182	0.26	Fam135a	family with sequence similarity 135, member A	13011	0.18
chr18_35681549_35681863	0.26	Dnajc18	DnaJ heat shock protein family (Hsp40) member C18	5037	0.1
chr6_5517592_5517751	0.26	Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	21362	0.26
chr14_45452880_45453061	0.26	Gm34250	predicted gene, 34250	5897	0.13
chr1_66895610_66896410	0.25	Gm25832	predicted gene, 25832	29213	0.09
chr13_12146494_12146649	0.25	Gm47323	predicted gene, 47323	14183	0.15
chr10_68269443_68270351	0.25	Arid5b	AT rich interactive domain 5B (MRF1-like)	8824	0.23
chr16_87128308_87128459	0.25	Gm32865	predicted gene, 32865	56	0.99
chr5_90471470_90471733	0.25	Alb	albumin	8901	0.15
chr15_75994277_75994580	0.25	Mapk15	mitogen-activated protein kinase 15	659	0.46
chr3_106457659_106457818	0.25	Gm38244	predicted gene, 38244	20545	0.13
chr14_35502504_35502655	0.25	Gm19016	predicted gene, 19016	46547	0.17
chr7_45264516_45264678	0.25	Slc6a16	solute carrier family 6, member 16	3553	0.09
chr6_88820995_88821174	0.25	Mgll	monoglyceride lipase	2046	0.19
chr10_123588527_123588968	0.25	Gm19169	predicted gene, 19169	5159	0.33
chr5_125491109_125491333	0.25	Gm27551	predicted gene, 27551	11844	0.13
chr8_85088891_85089042	0.25	Man2b1	mannosidase 2, alpha B1	2508	0.09
chr4_8361870_8362071	0.25	Gm37386	predicted gene, 37386	92277	0.08
chr19_21152410_21152561	0.25	AC106834.1	novel transcript	18356	0.2
chr12_12509285_12509462	0.25	4921511I17Rik	RIKEN cDNA 4921511I17 gene	116758	0.06
chr7_65338015_65338188	0.25	Tjp1	tight junction protein 1	4696	0.24
chr15_10273020_10273171	0.25	Prlr	prolactin receptor	23535	0.21
chr6_149344317_149344633	0.24	Gm15782	predicted gene 15782	9351	0.14
chr16_72734333_72734499	0.24	Robo1	roundabout guidance receptor 1	71212	0.14
chr2_39002726_39002905	0.24	Rpl35	ribosomal protein L35	2228	0.15
chr9_70245178_70245559	0.24	Myo1e	myosin IE	38000	0.16
chr17_83938813_83938978	0.24	Gm23905	predicted gene, 23905	8693	0.12
chr12_25281511_25281662	0.24	Gm19340	predicted gene, 19340	1009	0.54
chr4_150284112_150284294	0.24	Rere	arginine glutamic acid dipeptide (RE) repeats	2391	0.24
chr6_29833568_29833845	0.24	Ahcyl2	S-adenosylhomocysteine hydrolase-like 2	20054	0.17
chr12_110488367_110488518	0.24	Gm19605	predicted gene, 19605	2234	0.25
chr10_86793057_86793348	0.24	Nt5dc3	5'-nucleotidase domain containing 3	14197	0.11
chr11_87449212_87449363	0.24	Rnu3b3	U3B small nuclear RNA 3	660	0.48
chr19_59908738_59908900	0.24	Gm17203	predicted gene 17203	7757	0.21
chr1_182280533_182280736	0.24	Degs1	delta(4)-desaturase, sphingolipid 1	1590	0.35
chr17_63343186_63343351	0.24	Gm17228	predicted gene 17228	4142	0.22
chr1_24611857_24612019	0.24	Gm28439	predicted gene 28439	472	0.45
chrX_142456153_142456325	0.24	Gm25915	predicted gene, 25915	29208	0.13
chr8_66326515_66326676	0.24	Marchf1	membrane associated ring-CH-type finger 1	59699	0.12
chr13_16269739_16270144	0.24	Gm48491	predicted gene, 48491	7897	0.23
chr10_7832157_7832704	0.24	Zc3h12d	zinc finger CCCH type containing 12D	40	0.96
chr12_25092894_25093391	0.24	Id2	inhibitor of DNA binding 2	2945	0.22
chr10_9495311_9495462	0.24	Gm48751	predicted gene, 48751	8184	0.16
chr13_100543031_100543362	0.23	Ocln	occludin	9264	0.12
chr2_165999944_166000123	0.23	Ncoa3	nuclear receptor coactivator 3	7396	0.14
chr8_117677298_117677515	0.23	Gm31717	predicted gene, 31717	197	0.91
chr7_81243481_81243646	0.23	Gm7180	predicted pseudogene 7180	20689	0.14
chr2_48816834_48817005	0.23	Acvr2a	activin receptor IIA	2810	0.3
chr18_59082260_59082587	0.23	Minar2	membrane integral NOTCH2 associated receptor 2	19912	0.26
chr14_20319722_20320198	0.23	Nudt13	nudix (nucleoside diphosphate linked moiety X)-type motif 13	8531	0.12
chr12_112094362_112094513	0.23	Aspg	asparaginase	12242	0.12
chr11_16890762_16890930	0.23	Egfr	epidermal growth factor receptor	12696	0.19
chr10_53348308_53348525	0.23	Cep85l	centrosomal protein 85-like	1407	0.3
chr13_81328304_81328472	0.23	Adgrv1	adhesion G protein-coupled receptor V1	14448	0.26
chr9_64397221_64397372	0.23	Megf11	multiple EGF-like-domains 11	11610	0.2
chr3_104220440_104221564	0.22	Magi3	membrane associated guanylate kinase, WW and PDZ domain containing 3	628	0.6
chr12_80951376_80951574	0.22	Srsf5	serine and arginine-rich splicing factor 5	5099	0.14
chr2_64462379_64462613	0.22	Gm13577	predicted gene 13577	12453	0.27
chr4_98960279_98960453	0.22	Dock7	dedicator of cytokinesis 7	52	0.98
chr12_41044805_41045069	0.22	Gm47375	predicted gene, 47375	2	0.98
chr12_36155196_36155406	0.22	Bzw2	basic leucine zipper and W2 domains 2	1326	0.29
chr12_118299403_118299566	0.22	Sp4	trans-acting transcription factor 4	1884	0.44
chr10_116310601_116310804	0.22	Ptprb	protein tyrosine phosphatase, receptor type, B	9330	0.18
chr18_14503181_14503343	0.22	Gm50098	predicted gene, 50098	11257	0.23
chr11_19941290_19941474	0.22	Spred2	sprouty-related EVH1 domain containing 2	13188	0.26
chr5_66081550_66081734	0.22	Rbm47	RNA binding motif protein 47	348	0.81

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hmx3

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1	0.6	GO:0060613	fat pad development(GO:0060613)
0.1	0.3	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1	0.2	GO:0045196	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1	0.2	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.1	0.2	GO:0000087	mitotic M phase(GO:0000087)
0.1	0.2	GO:0034197	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1	0.2	GO:0060300	regulation of cytokine activity(GO:0060300)
0.1	0.2	GO:0032474	otolith morphogenesis(GO:0032474)
0.1	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	0.2	GO:0090365	regulation of mRNA modification(GO:0090365)
0.1	0.2	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.1	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.0	0.1	GO:0061625	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.1	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.3	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.1	GO:0030070	insulin processing(GO:0030070)
0.0	0.3	GO:0070269	pyroptosis(GO:0070269)
0.0	0.2	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0	0.1	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.1	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.2	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0010911	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0043134	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.0	0.1	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0	0.2	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.1	GO:0006393	termination of mitochondrial transcription(GO:0006393)
0.0	0.9	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.1	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.0	0.1	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.0	0.1	GO:0060178	regulation of exocyst localization(GO:0060178)
0.0	0.1	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.1	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.3	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.0	0.1	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.0	0.0	GO:1903660	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.1	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.0	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.0	0.1	GO:0001907	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.1	GO:0070671	response to interleukin-12(GO:0070671)
0.0	0.0	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.0	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:0046208	spermine catabolic process(GO:0046208)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0046881	positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.2	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0032875	regulation of DNA endoreduplication(GO:0032875)
0.0	0.1	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.1	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0	0.1	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0	0.0	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0	0.1	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.1	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	0.1	GO:0010255	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.0	0.1	GO:0015808	L-alanine transport(GO:0015808)
0.0	0.2	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.1	GO:0034653	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0	0.0	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.1	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.1	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.1	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.1	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.0	0.1	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.2	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:1903416	response to glycoside(GO:1903416)
0.0	0.1	GO:1904754	positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
0.0	0.1	GO:0019086	late viral transcription(GO:0019086)
0.0	0.0	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0	0.0	GO:0015755	fructose transport(GO:0015755)
0.0	0.0	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.1	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0010529	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0	0.1	GO:0051025	negative regulation of immunoglobulin secretion(GO:0051025)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.1	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.3	GO:0044458	motile cilium assembly(GO:0044458)
0.0	0.0	GO:2000836	androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.0	0.0	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.2	GO:0072673	lamellipodium morphogenesis(GO:0072673)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.0	GO:0006059	hexitol metabolic process(GO:0006059)
0.0	0.0	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.0	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.0	0.1	GO:0003149	membranous septum morphogenesis(GO:0003149)
0.0	0.0	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.0	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.0	0.0	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.0	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.0	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.0	0.1	GO:0097341	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.0	GO:0002159	desmosome assembly(GO:0002159)
0.0	0.1	GO:1904417	regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.0	GO:0014016	neuroblast differentiation(GO:0014016)
0.0	0.0	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
0.0	0.0	GO:0071504	response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.0	0.0	GO:0033092	positive regulation of immature T cell proliferation(GO:0033091) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0	0.0	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.0	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.0	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.0	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.1	GO:0046909	intermembrane transport(GO:0046909)
0.0	0.1	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.0	0.0	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.0	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.0	0.0	GO:0045726	positive regulation of integrin biosynthetic process(GO:0045726)
0.0	0.1	GO:0032570	response to progesterone(GO:0032570)
0.0	0.1	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.0	0.1	GO:0097012	response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.0	GO:0010025	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0	0.1	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.0	0.1	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.0	0.1	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.0	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.0	0.0	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.2	GO:1901798	positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.1	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.0	0.1	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.1	GO:0014063	negative regulation of serotonin secretion(GO:0014063)
0.0	0.0	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.2	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
0.0	0.1	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.3	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:0010992	ubiquitin homeostasis(GO:0010992)
0.0	0.0	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.1	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.0	0.0	GO:1904738	vascular associated smooth muscle cell migration(GO:1904738) regulation of vascular associated smooth muscle cell migration(GO:1904752)
0.0	0.1	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.0	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0	0.1	GO:0046984	regulation of hemoglobin biosynthetic process(GO:0046984)
0.0	0.0	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	0.0	GO:0043096	purine nucleobase salvage(GO:0043096)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.0	0.0	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0	0.0	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.0	0.0	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.0	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.0	0.0	GO:0009080	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
0.0	0.1	GO:0009115	xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
0.0	0.1	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.0	0.1	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.0	0.0	GO:0006598	polyamine catabolic process(GO:0006598)
0.0	0.0	GO:0061209	cell proliferation involved in mesonephros development(GO:0061209)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.0	0.1	GO:0045176	apical protein localization(GO:0045176)
0.0	0.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.0	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.1	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0	0.1	GO:0030575	nuclear body organization(GO:0030575)
0.0	0.0	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.0	0.0	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0	0.1	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.0	GO:2001168	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0	0.0	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0	0.0	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0	0.0	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.1	GO:0000022	mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0	0.1	GO:0018126	protein hydroxylation(GO:0018126)
0.0	0.1	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0	0.2	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.0	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.0	0.0	GO:0032196	transposition(GO:0032196)
0.0	0.0	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.0	0.1	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.0	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:0001553	luteinization(GO:0001553)
0.0	0.0	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.0	0.0	GO:1904431	positive regulation of t-circle formation(GO:1904431)
0.0	0.0	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.0	GO:1904995	negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0	0.0	GO:0006216	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.0	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0	0.0	GO:1901475	pyruvate transmembrane transport(GO:1901475)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.1	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.1	0.2	GO:0032010	phagolysosome(GO:0032010)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.2	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.0	0.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.3	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	0.1	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.3	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	0.1	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.0	GO:0033503	HULC complex(GO:0033503)
0.0	0.0	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.0	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.0	GO:0035838	growing cell tip(GO:0035838)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.0	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.2	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0000322	storage vacuole(GO:0000322)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520)
0.0	0.1	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.0	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.0	GO:0070876	SOSS complex(GO:0070876)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.0	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	0.0	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.0	0.0	GO:0033647	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0	0.0	GO:0046691	intracellular canaliculus(GO:0046691)
0.0	0.0	GO:0000125	PCAF complex(GO:0000125)
0.0	0.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.0	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0031209	SCAR complex(GO:0031209)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0048408	epidermal growth factor binding(GO:0048408)
0.1	0.5	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1	0.2	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.1	0.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.4	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.2	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0015526	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.2	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0030984	kininogen binding(GO:0030984)
0.0	0.2	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.2	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0032557	pyrimidine ribonucleotide binding(GO:0032557)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0	0.1	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.1	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.0	0.1	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.1	GO:0045340	mercury ion binding(GO:0045340)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.2	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0030519	snoRNP binding(GO:0030519)
0.0	0.1	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0	0.1	GO:0019158	fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0	0.2	GO:0036122	BMP binding(GO:0036122)
0.0	0.1	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.1	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.1	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:2001070	starch binding(GO:2001070)
0.0	0.1	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.0	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.0	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.2	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0015180	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.0	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.0	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.1	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.0	0.0	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.0	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.2	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0	0.1	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.1	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0060229	lipase activator activity(GO:0060229)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.0	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.0	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.0	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0034894	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.2	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0016623	aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.0	GO:0016453	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0	0.0	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.0	GO:0047105	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0	0.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.0	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.1	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.0	0.1	GO:0070061	fructose binding(GO:0070061)
0.0	0.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.0	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0016208	AMP binding(GO:0016208)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.8	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.3	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.3	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.3	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.5	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac