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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Hoxb2_Dlx2

Z-value: 0.54

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Transcription factors associated with Hoxb2_Dlx2

Gene Symbol	Gene ID	Gene Info
Hoxb2 Ensembl NCBI MGI UniProt	ENSMUSG00000075588.5	homeobox B2
Dlx2 Ensembl NCBI MGI UniProt	ENSMUSG00000023391.7	distal-less homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_71598083_71598272	Dlx2	51423	0.100078	0.82	4.7e-02	Click!
chr2_71627327_71627478	Dlx2	80648	0.062846	-0.44	3.8e-01	Click!
chr2_71607354_71607520	Dlx2	60683	0.087066	0.42	4.0e-01	Click!
chr2_71598676_71598833	Dlx2	52000	0.099245	0.38	4.6e-01	Click!
chr2_71598933_71599091	Dlx2	52258	0.098873	0.30	5.6e-01	Click!
chr11_96351817_96351975	Hoxb2	265	0.791269	-0.19	7.2e-01	Click!

Activity of the Hoxb2_Dlx2 motif across conditions

Conditions sorted by the z-value of the Hoxb2_Dlx2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_123124873_123125354	0.37	Tnrc6a	trinucleotide repeat containing 6a	857	0.66
chr13_45623869_45624201	0.34	Gmpr	guanosine monophosphate reductase	77882	0.1
chr19_23441277_23441430	0.33	Gm50443	predicted gene, 50443	3626	0.22
chr7_65367609_65368266	0.31	Gm44794	predicted gene 44794	1155	0.47
chr18_51150358_51150691	0.31	Prr16	proline rich 16	32786	0.23
chr13_80891058_80891263	0.30	Arrdc3	arrestin domain containing 3	642	0.68
chr11_20206679_20206887	0.30	Rab1a	RAB1A, member RAS oncogene family	5174	0.18
chr11_120810774_120811098	0.30	Fasn	fatty acid synthase	1235	0.26
chr8_48553802_48554548	0.30	Tenm3	teneurin transmembrane protein 3	1138	0.64
chr8_71699244_71699423	0.29	B3gnt3	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	2456	0.13
chr19_44400352_44400581	0.28	Scd1	stearoyl-Coenzyme A desaturase 1	6224	0.15
chr13_80896624_80897028	0.28	Arrdc3	arrestin domain containing 3	6308	0.17
chr5_125526040_125526191	0.28	Tmem132b	transmembrane protein 132B	5659	0.17
chr19_39648534_39649207	0.28	Cyp2c67	cytochrome P450, family 2, subfamily c, polypeptide 67	181	0.97
chr11_75734405_75734749	0.27	Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	1429	0.37
chr2_18048778_18049088	0.27	Skida1	SKI/DACH domain containing 1	98	0.94
chr19_31886956_31887132	0.27	A1cf	APOBEC1 complementation factor	18263	0.2
chr6_72155996_72156358	0.27	Gm38832	predicted gene, 38832	6672	0.15
chr4_76440655_76440825	0.27	Ptprd	protein tyrosine phosphatase, receptor type, D	9240	0.22
chr5_12476907_12477068	0.26	Gm8925	predicted gene 8925	2641	0.3
chr6_51177506_51178046	0.26	Mir148a	microRNA 148a	92134	0.08
chr4_102581954_102582116	0.26	Pde4b	phosphodiesterase 4B, cAMP specific	5523	0.32
chr3_102976188_102976339	0.25	Nr1h5	nuclear receptor subfamily 1, group H, member 5	12130	0.12
chr3_28701950_28702157	0.25	Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	4036	0.21
chr2_148017296_148017455	0.24	9030622O22Rik	RIKEN cDNA 9030622O22 gene	20895	0.16
chr15_10692675_10692891	0.24	Rai14	retinoic acid induced 14	20757	0.18
chr9_41328613_41328764	0.24	Mir100hg	Mir100 Mirlet7a-2 Mir125b-1 cluster host gene	78	0.97
chr13_80895235_80895839	0.24	Arrdc3	arrestin domain containing 3	5019	0.18
chr8_61309660_61309840	0.24	1700001D01Rik	RIKEN cDNA 1700001D01 gene	20878	0.18
chr12_73861884_73862127	0.24	Gm15283	predicted gene 15283	7607	0.18
chr9_44181035_44181211	0.23	5830462O15Rik	RIKEN cDNA 5830462O15 gene	422	0.42
chr6_52577244_52577395	0.23	Gm44445	predicted gene, 44445	16767	0.14
chr2_75202592_75202875	0.23	Gm13653	predicted gene 13653	10456	0.15
chr15_3463620_3463812	0.23	Ghr	growth hormone receptor	7928	0.3
chr2_45456676_45457076	0.23	Gm13479	predicted gene 13479	99611	0.08
chr13_52979672_52979858	0.23	Nfil3	nuclear factor, interleukin 3, regulated	1308	0.43
chr7_139559759_139559933	0.23	Nkx6-2	NK6 homeobox 2	22944	0.17
chr12_81484559_81484773	0.23	Cox16	cytochrome c oxidase assembly protein 16	163	0.91
chr14_61687749_61687952	0.23	Gm37820	predicted gene, 37820	4340	0.12
chr15_61562347_61562502	0.23	Gm49498	predicted gene, 49498	18241	0.28
chr9_115307686_115307849	0.22	Stt3b	STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)	2654	0.24
chr10_125785978_125786129	0.22	Lrig3	leucine-rich repeats and immunoglobulin-like domains 3	180115	0.03
chr15_10203363_10203587	0.22	Prlr	prolactin receptor	9990	0.29
chr6_117689133_117689284	0.22	Gm7292	predicted gene 7292	27134	0.16
chr16_97763100_97763270	0.22	Ripk4	receptor-interacting serine-threonine kinase 4	602	0.75
chr11_53419846_53420072	0.21	Leap2	liver-expressed antimicrobial peptide 2	3211	0.11
chr16_16990792_16991110	0.21	Mapk1	mitogen-activated protein kinase 1	7384	0.11
chr16_45996562_45996713	0.21	Plcxd2	phosphatidylinositol-specific phospholipase C, X domain containing 2	13581	0.16
chr19_26730650_26730825	0.21	Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	738	0.74
chr4_81502043_81502194	0.21	Gm11765	predicted gene 11765	40386	0.18
chr5_92607049_92607221	0.21	Stbd1	starch binding domain 1	4067	0.19
chr13_63665698_63665976	0.21	Gm47387	predicted gene, 47387	4040	0.18
chr9_74888354_74888522	0.21	Onecut1	one cut domain, family member 1	21954	0.14
chr8_53848667_53848818	0.21	Gm19921	predicted gene, 19921	62997	0.15
chr8_93189262_93189430	0.21	Gm45909	predicted gene 45909	2012	0.24
chr16_30110807_30110970	0.21	Gm20040	predicted gene, 20040	18006	0.13
chr9_106231818_106232229	0.21	Alas1	aminolevulinic acid synthase 1	5061	0.11
chr18_55506021_55506172	0.20	Gm37337	predicted gene, 37337	11018	0.3
chr13_80892366_80892552	0.20	Arrdc3	arrestin domain containing 3	1941	0.29
chr1_161240339_161240617	0.20	Prdx6	peroxiredoxin 6	10076	0.16
chr16_34095182_34095374	0.20	Kalrn	kalirin, RhoGEF kinase	709	0.77
chr11_120806039_120806735	0.20	Fasn	fatty acid synthase	2218	0.14
chr2_70666883_70667034	0.20	Gorasp2	golgi reassembly stacking protein 2	4758	0.18
chr10_20104280_20104431	0.20	Map3k5	mitogen-activated protein kinase kinase kinase 5	4830	0.24
chr4_9046133_9046293	0.20	Rps18-ps2	ribosomal protein S18, pseudogene 2	104954	0.07
chr5_17998832_17999006	0.20	Gnat3	guanine nucleotide binding protein, alpha transducing 3	36370	0.22
chr19_7500165_7500363	0.20	Atl3	atlastin GTPase 3	5729	0.15
chr4_9404895_9405097	0.20	Gm11817	predicted gene 11817	42203	0.16
chr10_95120058_95120242	0.20	Gm48868	predicted gene, 48868	3771	0.2
chr8_128359811_128359999	0.20	Nrp1	neuropilin 1	508	0.56
chr4_136470355_136470864	0.20	Luzp1	leucine zipper protein 1	759	0.6
chr3_60495047_60495368	0.20	Mbnl1	muscleblind like splicing factor 1	5728	0.26
chr10_110717138_110717467	0.20	E2f7	E2F transcription factor 7	28137	0.19
chr5_99234120_99234297	0.20	Rasgef1b	RasGEF domain family, member 1B	142	0.97
chr2_132130983_132131187	0.20	Gm14051	predicted gene 14051	13448	0.16
chr17_5232385_5232541	0.20	Gm15599	predicted gene 15599	120353	0.05
chr2_122737415_122737579	0.19	Bloc1s6os	biogenesis of lysosomal organelles complex-1, subunit 6, pallidin, opposite strand	865	0.39
chr11_71014838_71015021	0.19	Derl2	Der1-like domain family, member 2	4283	0.11
chr3_28712599_28712834	0.19	Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	8801	0.17
chr7_123125696_123126050	0.19	Tnrc6a	trinucleotide repeat containing 6a	1617	0.43
chr9_122848915_122849207	0.19	Gm47140	predicted gene, 47140	643	0.55
chr11_88522182_88522333	0.19	Msi2	musashi RNA-binding protein 2	67890	0.1
chr7_19508824_19509003	0.19	Trappc6a	trafficking protein particle complex 6A	183	0.76
chr9_46069702_46069853	0.19	Sik3	SIK family kinase 3	53353	0.09
chr3_96561912_96562186	0.19	Txnip	thioredoxin interacting protein	1995	0.13
chr16_31998270_31998421	0.19	Senp5	SUMO/sentrin specific peptidase 5	4818	0.09
chr14_122878269_122878430	0.19	Pcca	propionyl-Coenzyme A carboxylase, alpha polypeptide	2414	0.29
chr4_62102548_62102834	0.18	Gm12910	predicted gene 12910	10240	0.13
chr6_82067875_82068026	0.18	Gm15864	predicted gene 15864	15369	0.17
chr17_7864878_7865029	0.18	Fndc1	fibronectin type III domain containing 1	37651	0.15
chr8_123838618_123838800	0.18	2810455O05Rik	RIKEN cDNA 2810455O05 gene	2076	0.17
chr2_160865636_160865792	0.18	Zhx3	zinc fingers and homeoboxes 3	6083	0.14
chr7_45458826_45458977	0.18	Ftl1	ferritin light polypeptide 1	102	0.77
chr11_63703995_63704169	0.18	Gm12287	predicted gene 12287	103159	0.07
chr2_117128981_117129156	0.18	Spred1	sprouty protein with EVH-1 domain 1, related sequence	7430	0.22
chr1_153739671_153739993	0.18	Rgs16	regulator of G-protein signaling 16	517	0.61
chr19_39108442_39108835	0.18	Cyp2c66	cytochrome P450, family 2, subfamily c, polypeptide 66	5260	0.24
chr3_129545820_129545971	0.18	Elovl6	ELOVL family member 6, elongation of long chain fatty acids (yeast)	6485	0.17
chr4_11614681_11614832	0.18	Gm11832	predicted gene 11832	251	0.9
chr8_93078206_93078884	0.18	Ces1b	carboxylesterase 1B	1472	0.35
chr13_28096074_28096344	0.18	Gm47019	predicted gene, 47019	24148	0.18
chr6_71208408_71208680	0.18	Smyd1	SET and MYND domain containing 1	8330	0.12
chr19_3557401_3557552	0.18	Ppp6r3	protein phosphatase 6, regulatory subunit 3	18220	0.14
chr5_115560049_115560208	0.18	Rplp0	ribosomal protein, large, P0	505	0.63
chr5_22506386_22506555	0.18	Orc5	origin recognition complex, subunit 5	16196	0.12
chr12_33285610_33285770	0.18	Atxn7l1	ataxin 7-like 1	16825	0.2
chr4_116689870_116690150	0.18	Prdx1	peroxiredoxin 1	2698	0.15
chr3_79563335_79563486	0.18	Fnip2	folliculin interacting protein 2	4269	0.14
chr17_81176200_81176400	0.18	Gm50042	predicted gene, 50042	70438	0.11
chr7_132808519_132808670	0.18	Fam53b	family with sequence similarity 53, member B	1214	0.44
chr9_62121281_62121514	0.18	Mir5133	microRNA 5133	1197	0.36
chr17_28428613_28428954	0.18	Fkbp5	FK506 binding protein 5	154	0.91
chr7_115858420_115858571	0.18	Sox6	SRY (sex determining region Y)-box 6	1357	0.57
chr15_3721208_3721477	0.17	Gm4823	predicted gene 4823	25533	0.23
chr2_48441967_48442157	0.17	Gm13481	predicted gene 13481	15183	0.23
chr19_41581597_41581748	0.17	Lcor	ligand dependent nuclear receptor corepressor	698	0.68
chr11_106476283_106476462	0.17	Ern1	endoplasmic reticulum (ER) to nucleus signalling 1	11424	0.15
chr9_55277532_55277801	0.17	Nrg4	neuregulin 4	5906	0.19
chr15_11397598_11397751	0.17	Tars	threonyl-tRNA synthetase	1927	0.42
chr16_70325907_70326108	0.17	Gbe1	glucan (1,4-alpha-), branching enzyme 1	11873	0.25
chr3_10174352_10174597	0.17	Pmp2	peripheral myelin protein 2	9455	0.12
chr15_85773594_85773745	0.17	Ppara	peroxisome proliferator activated receptor alpha	1455	0.34
chr3_10239255_10239580	0.17	1700029B24Rik	RIKEN cDNA 1700029B24 gene	2395	0.16
chr9_67604985_67605321	0.17	Tln2	talin 2	45450	0.15
chr5_66979311_66979467	0.17	Limch1	LIM and calponin homology domains 1	2371	0.2
chr11_111605518_111605669	0.17	Gm11676	predicted gene 11676	7713	0.32
chr2_58766481_58766674	0.17	Upp2	uridine phosphorylase 2	1252	0.49
chr18_60606060_60606525	0.17	Synpo	synaptopodin	3813	0.19
chr2_156393156_156393343	0.17	2900097C17Rik	RIKEN cDNA 2900097C17 gene	270	0.81
chr4_123990670_123991070	0.17	Gm12902	predicted gene 12902	64636	0.08
chr8_125034718_125034906	0.17	Gm45874	predicted gene 45874	15641	0.14
chr2_57251739_57252164	0.17	Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	7589	0.16
chr12_57537353_57537539	0.17	Foxa1	forkhead box A1	8675	0.15
chr6_36281020_36281243	0.16	9330158H04Rik	RIKEN cDNA 9330158H04 gene	6775	0.29
chr12_72768361_72768564	0.16	Ppm1a	protein phosphatase 1A, magnesium dependent, alpha isoform	7147	0.2
chr4_97099326_97100044	0.16	Gm27521	predicted gene, 27521	182665	0.03
chr11_30774536_30774692	0.16	Psme4	proteasome (prosome, macropain) activator subunit 4	2293	0.25
chr19_44401904_44402310	0.16	Scd1	stearoyl-Coenzyme A desaturase 1	4583	0.17
chr2_64059065_64059258	0.16	Fign	fidgetin	38827	0.23
chr9_61471858_61472032	0.16	Gm47240	predicted gene, 47240	1041	0.54
chr17_32270584_32270735	0.16	Brd4	bromodomain containing 4	1706	0.26
chr18_35845094_35845245	0.16	Cxxc5	CXXC finger 5	9518	0.1
chr11_16854059_16854210	0.16	Egfros	epidermal growth factor receptor, opposite strand	23432	0.17
chr2_73276147_73276506	0.16	Sp9	trans-acting transcription factor 9	4360	0.18
chr4_123419872_123420087	0.16	Macf1	microtubule-actin crosslinking factor 1	7751	0.17
chr8_127185149_127185448	0.16	Pard3	par-3 family cell polarity regulator	13894	0.27
chr12_41246808_41247005	0.16	Gm47376	predicted gene, 47376	101184	0.07
chr10_30601093_30601268	0.16	Trmt11	tRNA methyltransferase 11	431	0.78
chr2_161071893_161072061	0.16	Chd6	chromodomain helicase DNA binding protein 6	19399	0.18
chr3_142862185_142862381	0.16	Pkn2	protein kinase N2	6548	0.15
chr13_75722257_75722538	0.16	Gm48302	predicted gene, 48302	4882	0.15
chr5_49305931_49306082	0.16	Kcnip4	Kv channel interacting protein 4	20347	0.19
chr9_23436438_23436789	0.16	Bmper	BMP-binding endothelial regulator	62681	0.16
chr9_59034763_59034914	0.16	Neo1	neogenin	1587	0.47
chr4_76366772_76366969	0.16	Ptprd	protein tyrosine phosphatase, receptor type, D	22627	0.21
chr15_77170014_77170165	0.15	Gm49411	predicted gene, 49411	8175	0.15
chr2_25751210_25751379	0.15	Lcn3	lipocalin 3	14275	0.08
chr12_70777982_70778133	0.15	Gm40437	predicted gene, 40437	47288	0.12
chr6_51826108_51826297	0.15	Skap2	src family associated phosphoprotein 2	45727	0.15
chr12_3696074_3696265	0.15	Gm26050	predicted gene, 26050	3009	0.26
chr11_22347754_22347975	0.15	Ehbp1	EH domain binding protein 1	5572	0.25
chr7_26881162_26881332	0.15	Cyp2a21-ps	cytochrome P450, family 2, subfamily a, polypeptide 21, pseudogene	36134	0.11
chr12_31712887_31713047	0.15	Gpr22	G protein-coupled receptor 22	959	0.51
chr9_25520943_25521129	0.15	Gm25861	predicted gene, 25861	18169	0.18
chr18_16736484_16736697	0.15	Gm15485	predicted gene 15485	7857	0.26
chr2_64093669_64093820	0.15	Fign	fidgetin	4244	0.37
chr2_122150264_122150420	0.15	B2m	beta-2 microglobulin	2656	0.17
chr2_50283993_50284144	0.15	Mmadhc	methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria	5131	0.24
chr7_26352806_26352980	0.15	Nlrp9c	NLR family, pyrin domain containing 9C	41345	0.1
chr11_95462552_95462764	0.15	Gm11522	predicted gene 11522	63	0.97
chr9_74377297_74377573	0.15	Nr1h2-ps	nuclear receptor subfamily 1, group H, member 2, pseudogene	12372	0.22
chr13_60173158_60174110	0.15	Gm48488	predicted gene, 48488	3048	0.21
chr8_89407033_89407242	0.15	Gm26331	predicted gene, 26331	182404	0.03
chr19_37507552_37507703	0.15	Exoc6	exocyst complex component 6	13252	0.16
chr3_57448063_57448221	0.15	Tm4sf4	transmembrane 4 superfamily member 4	22828	0.19
chr4_49535372_49535819	0.15	Aldob	aldolase B, fructose-bisphosphate	3271	0.17
chr13_69523823_69523979	0.15	Tent4a	terminal nucleotidyltransferase 4A	8531	0.13
chr9_15301981_15302132	0.15	4931406C07Rik	RIKEN cDNA 4931406C07 gene	500	0.46
chr4_122977007_122977265	0.15	4933421A08Rik	RIKEN cDNA 4933421A08 gene	15827	0.12
chr1_136939695_136939890	0.15	Nr5a2	nuclear receptor subfamily 5, group A, member 2	791	0.7
chr18_20654349_20654505	0.15	Gm16090	predicted gene 16090	10833	0.17
chr9_122118490_122118656	0.15	Gm47122	predicted gene, 47122	572	0.49
chr4_57294723_57294883	0.15	Gm12536	predicted gene 12536	5293	0.2
chr8_93164567_93164980	0.15	Ces1d	carboxylesterase 1D	5202	0.15
chr17_30632040_30632191	0.15	Dnah8	dynein, axonemal, heavy chain 8	3641	0.14
chr17_62785717_62785868	0.15	Efna5	ephrin A5	95352	0.09
chr2_73910165_73910316	0.15	Atp5g3	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)	219	0.94
chr2_122251200_122251358	0.15	Sord	sorbitol dehydrogenase	16530	0.1
chr6_38854042_38854267	0.15	Hipk2	homeodomain interacting protein kinase 2	16843	0.2
chr5_146239767_146239953	0.15	Cdk8	cyclin-dependent kinase 8	8475	0.12
chr10_122855244_122855438	0.15	Ppm1h	protein phosphatase 1H (PP2C domain containing)	40027	0.14
chr15_77153726_77153986	0.15	Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	44	0.97
chr19_32544319_32544470	0.15	Gm36419	predicted gene, 36419	1046	0.53
chr7_140724826_140724998	0.15	Olfr542-ps1	olfactory receptor 542, pseudogene 1	3630	0.12
chr3_122860456_122860802	0.15	Gm9364	predicted gene 9364	1284	0.37
chr15_64445338_64445505	0.15	Gm30563	predicted gene, 30563	49042	0.15
chr6_112944047_112944200	0.15	Srgap3	SLIT-ROBO Rho GTPase activating protein 3	2631	0.19
chr13_9097229_9097400	0.15	Larp4b	La ribonucleoprotein domain family, member 4B	3332	0.2
chr13_113595785_113595936	0.14	Snx18	sorting nexin 18	17781	0.16
chr12_3811591_3811763	0.14	Dnmt3a	DNA methyltransferase 3A	4517	0.2

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb2_Dlx2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	0.3	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1	0.4	GO:0046449	creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.2	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	0.2	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.1	0.3	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1	0.1	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.1	0.3	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.2	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	0.2	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.1	0.3	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.2	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	0.1	GO:0060375	regulation of mast cell differentiation(GO:0060375)
0.1	0.2	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.1	0.2	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	0.2	GO:0090365	regulation of mRNA modification(GO:0090365)
0.1	0.2	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1	0.2	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.1	0.2	GO:0003383	apical constriction(GO:0003383)
0.0	0.1	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0	0.1	GO:1903232	melanosome assembly(GO:1903232)
0.0	1.4	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.3	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.1	GO:0048696	regulation of collateral sprouting in absence of injury(GO:0048696)
0.0	0.1	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.0	0.1	GO:1904339	negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0	0.2	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.2	GO:0044597	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:0097167	circadian regulation of translation(GO:0097167)
0.0	0.3	GO:0097264	self proteolysis(GO:0097264)
0.0	0.4	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.0	0.1	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.1	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0	0.1	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.1	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.2	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.1	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.2	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.1	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.0	0.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.1	GO:0061144	alveolar secondary septum development(GO:0061144)
0.0	0.1	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.0	0.2	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.0	0.1	GO:0071798	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0	0.1	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.0	0.1	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.0	0.1	GO:0015747	urate transport(GO:0015747)
0.0	0.2	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.0	0.1	GO:0046552	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0	0.2	GO:0015684	ferrous iron transport(GO:0015684)
0.0	0.1	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.1	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.0	0.1	GO:0034436	glycoprotein transport(GO:0034436)
0.0	0.1	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.2	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.2	GO:0061042	vascular wound healing(GO:0061042)
0.0	0.1	GO:1990168	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0039533	regulation of MDA-5 signaling pathway(GO:0039533)
0.0	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.0	0.1	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	0.1	GO:0061010	gall bladder development(GO:0061010)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.3	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.1	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0	0.1	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.0	0.1	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0	0.1	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.3	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.1	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.0	0.1	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.0	0.1	GO:0009732	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0010159	specification of organ position(GO:0010159)
0.0	0.0	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.1	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.0	0.1	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.0	0.1	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.0	0.1	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0	0.0	GO:0060685	regulation of prostatic bud formation(GO:0060685)
0.0	0.1	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.0	0.0	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	0.2	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.1	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.1	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.1	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.0	0.1	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.1	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.0	0.0	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0	0.1	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.0	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
0.0	0.1	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.0	GO:0036016	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0	0.1	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.0	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.2	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0	0.0	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.0	GO:0071332	cellular response to fructose stimulus(GO:0071332)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.1	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.1	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0	0.1	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.0	0.1	GO:0015772	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242)
0.0	0.1	GO:0021524	visceral motor neuron differentiation(GO:0021524)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.0	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.0	0.0	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0	0.1	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0035799	ureter maturation(GO:0035799)
0.0	0.1	GO:0036023	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0	0.1	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.0	GO:0060486	Clara cell differentiation(GO:0060486)
0.0	0.1	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:2000973	regulation of pro-B cell differentiation(GO:2000973)
0.0	0.1	GO:0071677	positive regulation of mononuclear cell migration(GO:0071677)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0	0.0	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0	0.1	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0	0.1	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.0	0.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.1	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.0	0.1	GO:0051890	regulation of cardioblast differentiation(GO:0051890)
0.0	0.0	GO:1990791	dorsal root ganglion development(GO:1990791)
0.0	0.3	GO:0031065	positive regulation of histone deacetylation(GO:0031065)
0.0	0.0	GO:0039535	regulation of RIG-I signaling pathway(GO:0039535)
0.0	0.1	GO:0045713	low-density lipoprotein particle receptor biosynthetic process(GO:0045713) regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0	0.2	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0034312	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.0	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.0	0.1	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0	0.0	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.0	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.0	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.0	GO:0061153	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0	0.1	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.2	GO:0042407	cristae formation(GO:0042407)
0.0	0.0	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.1	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.0	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.0	0.1	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.0	GO:1901656	glycoside transport(GO:1901656)
0.0	0.1	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	0.0	GO:0035087	siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0	0.0	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.0	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.0	0.0	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0	0.0	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.0	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0	0.0	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.0	0.1	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.0	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.0	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.0	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0000459	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.1	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.0	GO:0008050	female courtship behavior(GO:0008050)
0.0	0.0	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0	0.0	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.0	0.0	GO:0035459	cargo loading into vesicle(GO:0035459)
0.0	0.1	GO:0048087	positive regulation of developmental pigmentation(GO:0048087) positive regulation of pigment cell differentiation(GO:0050942)
0.0	0.2	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.0	GO:0007227	signal transduction downstream of smoothened(GO:0007227)
0.0	0.0	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.0	0.0	GO:0032741	positive regulation of interleukin-18 production(GO:0032741)
0.0	0.1	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.1	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.0	0.1	GO:0034091	regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
0.0	0.0	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.0	0.0	GO:0035864	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0	0.0	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.1	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.0	GO:0071727	response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0	0.0	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.0	GO:0046881	positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.1	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.1	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	0.0	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0046416	D-amino acid metabolic process(GO:0046416)
0.0	0.0	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.0	0.0	GO:0003133	BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.0	0.1	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0	0.0	GO:0002155	regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0	0.0	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0042473	outer ear morphogenesis(GO:0042473)
0.0	0.1	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.1	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.0	0.1	GO:0060546	negative regulation of necroptotic process(GO:0060546)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.0	GO:0048370	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.0	0.0	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.0	0.1	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.0	GO:0045200	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) asymmetric neuroblast division(GO:0055059)
0.0	0.0	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0	0.0	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0	0.0	GO:0060353	regulation of cell adhesion molecule production(GO:0060353)
0.0	0.0	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0	0.0	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.0	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.0	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0	0.1	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0	0.1	GO:0035278	miRNA mediated inhibition of translation(GO:0035278)
0.0	0.0	GO:0046459	short-chain fatty acid metabolic process(GO:0046459)
0.0	0.0	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.1	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.1	GO:0045176	apical protein localization(GO:0045176)
0.0	0.0	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.0	GO:0045634	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0	0.1	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
0.0	0.2	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.1	GO:0006743	ubiquinone metabolic process(GO:0006743)
0.0	0.0	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.0	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.0	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.0	GO:0060126	somatotropin secreting cell differentiation(GO:0060126)
0.0	0.1	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.0	0.1	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.0	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.3	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.0	0.0	GO:1904238	pericyte cell differentiation(GO:1904238)
0.0	0.0	GO:0001555	oocyte growth(GO:0001555)
0.0	0.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.0	GO:1904683	regulation of metalloendopeptidase activity(GO:1904683)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.2	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	0.0	GO:1990928	response to amino acid starvation(GO:1990928)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.0	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0	0.0	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.0	GO:1902915	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.1	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.0	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0	0.0	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.0	0.0	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.0	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.2	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2	GO:0033269	internode region of axon(GO:0033269)
0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	GO:0035838	growing cell tip(GO:0035838)
0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.2	GO:0045098	type III intermediate filament(GO:0045098)
0.2	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.3	GO:0016514	SWI/SNF complex(GO:0016514)
0.2	GO:0045179	apical cortex(GO:0045179)
0.1	GO:0045293	mRNA editing complex(GO:0045293)
0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	GO:0030478	actin cap(GO:0030478)
0.2	GO:0042587	glycogen granule(GO:0042587)
0.1	GO:1990111	spermatoproteasome complex(GO:1990111)
0.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.3	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	GO:0097149	centralspindlin complex(GO:0097149)
0.2	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	GO:0048179	activin receptor complex(GO:0048179)
0.3	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	GO:0097443	sorting endosome(GO:0097443)
0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	GO:0046691	intracellular canaliculus(GO:0046691)
0.1	GO:0097433	dense body(GO:0097433)
0.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.2	GO:0031083	BLOC-1 complex(GO:0031083)
0.1	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	GO:0000938	GARP complex(GO:0000938)
0.1	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.2	GO:0002102	podosome(GO:0002102)
0.1	GO:0033503	HULC complex(GO:0033503)
0.0	GO:0043511	inhibin complex(GO:0043511)
0.0	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	GO:0042583	chromaffin granule(GO:0042583)
0.0	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1	GO:0001939	female pronucleus(GO:0001939)
0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	GO:0042585	germinal vesicle(GO:0042585)
0.1	GO:0033263	CORVET complex(GO:0033263)
0.1	GO:1990909	Wnt signalosome(GO:1990909)
0.0	GO:0072487	MSL complex(GO:0072487)
0.4	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.1	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1	GO:0002177	manchette(GO:0002177)
0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	GO:0035102	PRC1 complex(GO:0035102)
0.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	GO:0032797	SMN complex(GO:0032797)
0.0	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0004771	sterol esterase activity(GO:0004771)
0.1	0.5	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1	0.3	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	0.2	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.2	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1	0.2	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1	0.2	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.2	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0	0.1	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.2	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.2	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.2	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.0	0.1	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0070538	oleic acid binding(GO:0070538)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0070699	type II activin receptor binding(GO:0070699)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.2	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0042731	PH domain binding(GO:0042731)
0.0	0.1	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.3	GO:0070034	telomerase RNA binding(GO:0070034)
0.0	0.1	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.1	GO:0070905	serine binding(GO:0070905)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.7	GO:0018732	prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.3	GO:0031690	adrenergic receptor binding(GO:0031690)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.8	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391)
0.0	0.1	GO:0015157	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.2	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.2	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.0	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.0	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
0.0	0.0	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.0	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.6	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.0	GO:2001069	glycogen binding(GO:2001069)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.2	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0018634	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.0	0.1	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.2	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0001602	pancreatic polypeptide receptor activity(GO:0001602)
0.0	0.2	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.1	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.2	GO:0060229	lipase activator activity(GO:0060229)
0.0	0.1	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.0	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.4	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.0	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0	0.1	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0070061	fructose binding(GO:0070061)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0016208	AMP binding(GO:0016208)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.0	0.0	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.0	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0016443	bidentate ribonuclease III activity(GO:0016443)
0.0	0.0	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.0	GO:0051731	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.0	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.3	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.0	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.0	0.0	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.0	0.0	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.0	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.0	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.0	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.0	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.0	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.0	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.4	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.0	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.0	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0070191	methionine-R-sulfoxide reductase activity(GO:0070191)
0.0	0.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.0	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.0	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.7	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.4	PID ALK1 PATHWAY	ALK1 signaling events
0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.2	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.6	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.2	PID ERBB4 PATHWAY	ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.2	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.3	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.0	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.0	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.0	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.2	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac

Results for Hoxb2_Dlx2

Z-value: 0.54

Motif logo

Transcription factors associated with Hoxb2_Dlx2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Hoxb2_Dlx2 motif across conditions

Conditions sorted by the z-value of the Hoxb2_Dlx2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb2_Dlx2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: