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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Hoxb5

Z-value: 1.99

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Transcription factors associated with Hoxb5

Gene Symbol	Gene ID	Gene Info
Hoxb5 Ensembl NCBI MGI UniProt	ENSMUSG00000038700.3	homeobox B5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr11_96303209_96303398	Hoxb5	33	0.921156	-0.50	3.1e-01	Click!

Activity of the Hoxb5 motif across conditions

Conditions sorted by the z-value of the Hoxb5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_74886235_74886449	1.83	Onecut1	one cut domain, family member 1	19858	0.14
chr17_57200639_57201014	1.54	Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	6649	0.11
chr18_33437665_33437816	1.44	Nrep	neuronal regeneration related protein	25695	0.18
chr16_41161594_41161767	1.30	Gm26381	predicted gene, 26381	56065	0.15
chr14_69626550_69626701	1.13	Gm37513	predicted gene, 37513	10579	0.11
chr5_33466079_33466243	1.09	Gm43851	predicted gene 43851	28697	0.15
chr5_33459431_33459801	1.01	Gm43851	predicted gene 43851	22152	0.16
chr18_20652197_20652348	0.97	Gm16090	predicted gene 16090	12988	0.16
chrX_140591087_140591238	0.96	AL683809.1	TSC22 domain family, member 3 (Tsc22d3), pseuodgene	7563	0.17
chr2_58791731_58791950	0.96	Upp2	uridine phosphorylase 2	26515	0.17
chr11_16841273_16841607	0.95	Egfros	epidermal growth factor receptor, opposite strand	10738	0.21
chr6_70874493_70874669	0.94	Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	3980	0.17
chr13_51095199_51095382	0.90	Spin1	spindlin 1	5590	0.26
chr1_100497686_100497861	0.89	Gm18700	predicted gene, 18700	99302	0.08
chr1_67138759_67139000	0.87	Cps1	carbamoyl-phosphate synthetase 1	15853	0.23
chr4_100398171_100398368	0.84	Gm12706	predicted gene 12706	36210	0.19
chr15_81301984_81302161	0.82	8430426J06Rik	RIKEN cDNA 8430426J06 gene	10794	0.15
chr17_57200072_57200273	0.76	Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	5995	0.12
chr9_74893793_74894014	0.76	Onecut1	one cut domain, family member 1	27419	0.13
chr16_43170805_43170956	0.76	Gm15712	predicted gene 15712	13693	0.21
chr8_126928052_126928350	0.75	Gm26397	predicted gene, 26397	16779	0.14
chr9_98423199_98423389	0.73	Rbp1	retinol binding protein 1, cellular	333	0.9
chr1_185608227_185608404	0.72	5033404E19Rik	RIKEN cDNA 5033404E19 gene	110927	0.05
chr1_55685863_55686014	0.71	Plcl1	phospholipase C-like 1	16087	0.27
chr2_58779732_58779883	0.71	Upp2	uridine phosphorylase 2	14482	0.2
chr19_55099918_55100172	0.70	Gm31356	predicted gene, 31356	543	0.49
chr19_44399803_44399962	0.70	Scd1	stearoyl-Coenzyme A desaturase 1	6808	0.15
chr16_37875038_37875343	0.69	Lrrc58	leucine rich repeat containing 58	6801	0.14
chr7_114232335_114232486	0.69	Copb1	coatomer protein complex, subunit beta 1	14249	0.19
chr1_133645585_133645754	0.68	Zc3h11a	zinc finger CCCH type containing 11A	6499	0.14
chr2_175276086_175276252	0.68	Gm14440	predicted gene 14440	1044	0.42
chr12_104346326_104346873	0.67	Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	8113	0.12
chr12_32690066_32690384	0.67	Gm47937	predicted gene, 47937	16931	0.2
chr2_176424621_176424782	0.66	Zfp968-ps	zinc finger protein 968, pseudogene	1040	0.53
chr9_7943950_7944118	0.65	Yap1	yes-associated protein 1	21787	0.15
chr15_3413229_3413380	0.65	Ghr	growth hormone receptor	58340	0.14
chr10_68137101_68137496	0.65	Arid5b	AT rich interactive domain 5B (MRF1-like)	672	0.78
chr8_34927398_34927800	0.65	Tnks	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	8831	0.2
chr19_40184696_40184852	0.64	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	2512	0.23
chr2_175799904_175800073	0.64	Gm14288	predicted gene 14288	973	0.46
chr19_40184875_40185171	0.64	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	2263	0.24
chr2_177499192_177499383	0.63	Gm14403	predicted gene 14403	972	0.52
chr9_44078711_44078862	0.63	Usp2	ubiquitin specific peptidase 2	6153	0.07
chr11_77216718_77216887	0.63	Ssh2	slingshot protein phosphatase 2	515	0.72
chr7_16576614_16576765	0.63	Gm29443	predicted gene 29443	37135	0.07
chrX_23364676_23365159	0.62	Klhl13	kelch-like 13	136	0.51
chr9_32243733_32243884	0.62	Arhgap32	Rho GTPase activating protein 32	1356	0.48
chr17_57198093_57198326	0.62	Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	4032	0.13
chr2_31476497_31476676	0.61	Ass1	argininosuccinate synthetase 1	6379	0.2
chr9_110985950_110986443	0.61	1700061E17Rik	RIKEN cDNA 1700061E17 gene	5	0.94
chr10_95234014_95234323	0.61	Gm48874	predicted gene, 48874	73807	0.07
chr17_57199524_57200036	0.60	Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	5603	0.12
chr16_37596956_37597107	0.60	Gm46559	predicted gene, 46559	841	0.55
chr6_13676526_13676747	0.59	Bmt2	base methyltransferase of 25S rRNA 2	1302	0.55
chr9_74693880_74694046	0.59	Gm27233	predicted gene 27233	15299	0.23
chr6_114877506_114877696	0.57	Vgll4	vestigial like family member 4	2494	0.3
chr2_26021405_26022065	0.57	Ubac1	ubiquitin associated domain containing 1	12	0.97
chr6_48445383_48445907	0.57	Zfp467	zinc finger protein 467	48	0.95
chr2_180678351_180678502	0.57	Dido1	death inducer-obliterator 1	2471	0.19
chr11_119038095_119038250	0.57	Cbx8	chromobox 8	2659	0.22
chr5_129941480_129942081	0.56	Vkorc1l1	vitamin K epoxide reductase complex, subunit 1-like 1	190	0.89
chr15_55152954_55153171	0.56	Deptor	DEP domain containing MTOR-interacting protein	19609	0.17
chr15_59008383_59008581	0.56	4930544F09Rik	RIKEN cDNA 4930544F09 gene	24346	0.16
chr8_10030198_10030353	0.55	Tnfsf13b	tumor necrosis factor (ligand) superfamily, member 13b	1043	0.48
chr3_51230122_51230437	0.55	Gm38357	predicted gene, 38357	1638	0.29
chr15_66578165_66578401	0.54	Phf20l1	PHD finger protein 20-like 1	678	0.73
chr4_150587732_150587916	0.54	Rere	arginine glutamic acid dipeptide (RE) repeats	18167	0.18
chr5_120484543_120484824	0.54	Gm15690	predicted gene 15690	3780	0.13
chr3_149181265_149181842	0.52	Gm42647	predicted gene 42647	28718	0.19
chr12_7751611_7751762	0.52	Gm32828	predicted gene, 32828	108005	0.06
chr3_89140809_89141081	0.52	Pklr	pyruvate kinase liver and red blood cell	4322	0.08
chr4_139631622_139632150	0.51	Aldh4a1	aldehyde dehydrogenase 4 family, member A1	8777	0.14
chr3_111102424_111102592	0.51	Gm43407	predicted gene 43407	5992	0.34
chr7_114420923_114421192	0.51	Pde3b	phosphodiesterase 3B, cGMP-inhibited	5776	0.23
chr2_177898137_177898301	0.51	Gm14327	predicted gene 14327	1123	0.41
chr2_90560658_90560846	0.50	Ptprj	protein tyrosine phosphatase, receptor type, J	19895	0.2
chr17_63010676_63010827	0.50	Gm25348	predicted gene, 25348	86249	0.1
chr11_99050175_99050326	0.50	Igfbp4	insulin-like growth factor binding protein 4	2939	0.17
chr2_156729623_156729805	0.49	Dlgap4	DLG associated protein 4	8222	0.14
chr13_21917052_21917354	0.49	Gm44456	predicted gene, 44456	7813	0.07
chr15_7135984_7136307	0.48	Lifr	LIF receptor alpha	4397	0.32
chr5_99284196_99284371	0.48	Gm35394	predicted gene, 35394	10188	0.24
chr5_125528990_125529141	0.48	Tmem132b	transmembrane protein 132B	2709	0.23
chr15_58947289_58947444	0.47	Mtss1	MTSS I-BAR domain containing 1	6214	0.14
chr11_16859692_16859843	0.47	Egfr	epidermal growth factor receptor	18383	0.18
chr18_12727402_12727927	0.47	Ttc39c	tetratricopeptide repeat domain 39C	7041	0.14
chr7_130989257_130989408	0.46	Htra1	HtrA serine peptidase 1	6602	0.21
chr6_146270994_146271175	0.46	Gm44086	predicted gene, 44086	104	0.97
chr17_25127135_25127453	0.46	Clcn7	chloride channel, voltage-sensitive 7	6097	0.1
chr11_79340199_79340405	0.46	Nf1	neurofibromin 1	415	0.82
chr19_8993151_8993324	0.46	Ahnak	AHNAK nucleoprotein (desmoyokin)	3942	0.11
chr9_40804588_40804799	0.45	Snord14e	small nucleolar RNA, C/D box 14E	55	0.66
chr8_25609907_25610083	0.45	Gm23184	predicted gene, 23184	563	0.58
chr18_35748735_35748902	0.45	Sting1	stimulator of interferon response cGAMP interactor 1	8264	0.1
chr7_140723099_140723551	0.45	Olfr542-ps1	olfactory receptor 542, pseudogene 1	2043	0.18
chrX_42068446_42068784	0.45	Xiap	X-linked inhibitor of apoptosis	140	0.97
chr3_129444766_129445057	0.44	Gm5712	predicted gene 5712	11238	0.17
chr2_177901070_177901508	0.44	Gm14327	predicted gene 14327	2996	0.19
chr5_116020452_116020643	0.44	Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	1099	0.39
chr5_144255609_144256174	0.44	2900089D17Rik	RIKEN cDNA 2900089D17 gene	295	0.71
chr18_74301601_74301911	0.43	Gm14328	predicted gene 14328	2175	0.26
chr13_9073792_9074124	0.43	Gm36264	predicted gene, 36264	2493	0.23
chr3_18191923_18192090	0.43	Gm23686	predicted gene, 23686	14381	0.22
chr11_16902164_16902468	0.43	Egfr	epidermal growth factor receptor	2869	0.27
chr1_179108579_179108982	0.43	Smyd3	SET and MYND domain containing 3	119435	0.06
chr6_42360337_42360550	0.43	Zyx	zyxin	5306	0.09
chr11_16795963_16796156	0.43	Egfros	epidermal growth factor receptor, opposite strand	34643	0.15
chr8_115830669_115830820	0.43	Maf	avian musculoaponeurotic fibrosarcoma oncogene homolog	122950	0.06
chr6_145866005_145866307	0.42	Bhlhe41	basic helix-loop-helix family, member e41	598	0.7
chr5_24424830_24425266	0.42	Slc4a2	solute carrier family 4 (anion exchanger), member 2	184	0.83
chr7_139020930_139021245	0.42	Gm45613	predicted gene 45613	88	0.97
chr15_103250533_103250768	0.42	Nfe2	nuclear factor, erythroid derived 2	815	0.45
chr2_178024005_178024418	0.42	Zfp971	zinc finger protein 971	832	0.62
chr2_31477009_31477347	0.41	Ass1	argininosuccinate synthetase 1	6971	0.19
chr4_108059486_108059709	0.41	Scp2	sterol carrier protein 2, liver	11718	0.13
chr2_160805166_160805505	0.41	Gm11447	predicted gene 11447	40278	0.11
chr2_58761406_58761587	0.41	Upp2	uridine phosphorylase 2	3829	0.24
chr7_99164077_99164275	0.41	Dgat2	diacylglycerol O-acyltransferase 2	5930	0.14
chr5_137115772_137116317	0.41	Trim56	tripartite motif-containing 56	163	0.92
chr2_51145289_51145440	0.40	Rnd3	Rho family GTPase 3	3730	0.3
chr7_127026907_127027653	0.40	Maz	MYC-associated zinc finger protein (purine-binding transcription factor)	243	0.69
chr11_70653511_70654114	0.40	Pfn1	profilin 1	786	0.31
chr4_109721933_109722084	0.39	Gm12808	predicted gene 12808	32809	0.15
chr2_148034677_148034980	0.39	9030622O22Rik	RIKEN cDNA 9030622O22 gene	3442	0.21
chr13_48533860_48534011	0.39	Mirlet7d	microRNA let7d	2179	0.14
chr13_67194609_67194806	0.39	Zfp455	zinc finger protein 455	172	0.88
chr2_27244113_27244980	0.39	Sardh	sarcosine dehydrogenase	2302	0.25
chr10_87870357_87870520	0.39	Igf1os	insulin-like growth factor 1, opposite strand	7057	0.21
chr12_12800018_12800179	0.39	Platr19	pluripotency associated transcript 19	12113	0.19
chr16_13359323_13359477	0.39	Mrtfb	myocardin related transcription factor B	979	0.59
chr2_177839201_177839672	0.39	Gm14325	predicted gene 14325	882	0.56
chr10_78245322_78245474	0.39	Trappc10	trafficking protein particle complex 10	757	0.49
chr11_119085344_119085795	0.39	Cbx4	chromobox 4	652	0.65
chr13_24375115_24375330	0.39	Gm11342	predicted gene 11342	728	0.42
chr3_105686569_105686720	0.39	Ddx20	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20	800	0.53
chr8_123805341_123805997	0.38	Rab4a	RAB4A, member RAS oncogene family	316	0.79
chr9_74868189_74868408	0.38	Onecut1	one cut domain, family member 1	1814	0.29
chr1_160260042_160260204	0.38	Gm36975	predicted gene, 36975	4201	0.16
chr4_53217859_53218037	0.38	4930412L05Rik	RIKEN cDNA 4930412L05 gene	91	0.97
chr17_46052426_46052577	0.38	Vegfa	vascular endothelial growth factor A	20132	0.13
chr5_150452004_150452186	0.38	Fry	FRY microtubule binding protein	965	0.43
chrX_142517055_142517225	0.38	Gm4995	predicted pseudogene 4995	16730	0.18
chr2_154868249_154868417	0.37	Eif2s2	eukaryotic translation initiation factor 2, subunit 2 (beta)	24449	0.17
chr18_33337551_33337772	0.37	Gm5503	predicted gene 5503	47294	0.17
chr9_35116903_35117294	0.37	St3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	225	0.59
chr10_80577672_80578424	0.37	Klf16	Kruppel-like factor 16	727	0.41
chr10_111960652_111960806	0.37	Krr1	KRR1, small subunit (SSU) processome component, homolog (yeast)	11935	0.16
chr8_93183570_93183871	0.37	Gm45909	predicted gene 45909	7638	0.14
chr1_166409283_166409518	0.37	Pogk	pogo transposable element with KRAB domain	9	0.97
chr5_125021735_125021920	0.37	Ncor2	nuclear receptor co-repressor 2	1393	0.4
chr15_59078380_59078599	0.37	Mtss1	MTSS I-BAR domain containing 1	3500	0.29
chr3_130634058_130634674	0.36	Etnppl	ethanolamine phosphate phospholyase	7846	0.17
chr11_76803310_76803471	0.36	Cpd	carboxypeptidase D	5436	0.22
chr1_74026626_74026783	0.36	Tns1	tensin 1	10282	0.22
chr6_119446088_119446268	0.36	Wnt5b	wingless-type MMTV integration site family, member 5B	3208	0.25
chr12_100393204_100393374	0.36	Ttc7b	tetratricopeptide repeat domain 7B	7389	0.18
chr1_175633873_175634052	0.36	Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	1723	0.33
chr9_44512040_44512495	0.36	Bcl9l	B cell CLL/lymphoma 9-like	12995	0.07
chr19_4596445_4596623	0.36	Pcx	pyruvate carboxylase	2126	0.2
chr2_77506322_77506668	0.36	Zfp385b	zinc finger protein 385B	13040	0.24
chr10_69192399_69192560	0.35	Rhobtb1	Rho-related BTB domain containing 1	16073	0.16
chr15_62743599_62743898	0.35	Gm22521	predicted gene, 22521	49453	0.17
chr11_108344097_108344385	0.35	Prkca	protein kinase C, alpha	313	0.79
chr17_30111153_30111304	0.35	Zfand3	zinc finger, AN1-type domain 3	24962	0.16
chr7_130225038_130225258	0.35	Fgfr2	fibroblast growth factor receptor 2	3608	0.34
chr11_19851376_19851638	0.35	Gm12029	predicted gene 12029	67855	0.1
chr7_19756083_19756234	0.35	Bcam	basal cell adhesion molecule	793	0.37
chr1_31072664_31072818	0.35	4931428L18Rik	RIKEN cDNA 4931428L18 gene	23713	0.14
chr4_106441548_106441699	0.34	Usp24	ubiquitin specific peptidase 24	13130	0.15
chr11_16819306_16819457	0.34	Egfros	epidermal growth factor receptor, opposite strand	11321	0.22
chr7_35107621_35107973	0.34	Gm22535	predicted gene, 22535	5975	0.1
chr5_28079954_28080114	0.34	Insig1	insulin induced gene 1	5368	0.18
chr5_96737616_96737767	0.34	Gm42604	predicted gene 42604	1673	0.39
chr8_40874097_40874545	0.34	Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	627	0.68
chr19_26606580_26606779	0.34	Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	591	0.75
chr8_93181874_93182111	0.34	Ces1d	carboxylesterase 1D	6703	0.14
chr2_122245449_122245959	0.34	Sord	sorbitol dehydrogenase	10955	0.11
chr7_101178542_101179097	0.34	Fchsd2	FCH and double SH3 domains 2	11424	0.17
chr19_39347329_39347591	0.34	Cyp2c72-ps	cytochrome P450, family 2, subfamily c, polypeptide 72, pseudogene	93	0.98
chr9_86675546_86675705	0.34	Gm38230	predicted gene, 38230	9583	0.12
chr14_121093961_121094139	0.33	Farp1	FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)	8029	0.29
chr3_52007468_52007706	0.33	Gm37465	predicted gene, 37465	3562	0.16
chr9_43224415_43225053	0.33	Oaf	out at first homolog	358	0.84
chr19_44393747_44393961	0.33	Scd1	stearoyl-Coenzyme A desaturase 1	12836	0.14
chr17_24896022_24896534	0.33	Nme3	NME/NM23 nucleoside diphosphate kinase 3	222	0.77
chr11_63897172_63897366	0.33	Hs3st3b1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	25021	0.18
chr4_151953083_151953245	0.33	Dnajc11	DnaJ heat shock protein family (Hsp40) member C11	3979	0.16
chr12_16947098_16947259	0.33	Gm22303	predicted gene, 22303	7184	0.16
chr3_34020715_34021194	0.33	Fxr1	fragile X mental retardation gene 1, autosomal homolog	846	0.39
chr11_107326151_107326306	0.33	Gm11719	predicted gene 11719	4480	0.17
chr2_27710975_27711350	0.33	Rxra	retinoid X receptor alpha	579	0.83
chr6_88737581_88737810	0.33	Gm44005	predicted gene, 44005	497	0.7
chr13_101478901_101479052	0.33	Gm36994	predicted gene, 36994	35725	0.15
chr8_103501684_103501874	0.33	Gm45277	predicted gene 45277	61844	0.14
chr15_39845407_39845558	0.33	Dpys	dihydropyrimidinase	11985	0.21
chr18_12669046_12669223	0.33	Ttc39c	tetratricopeptide repeat domain 39C	20594	0.13
chr7_27332366_27332527	0.33	Ltbp4	latent transforming growth factor beta binding protein 4	1167	0.33
chr11_4822321_4822472	0.33	Nf2	neurofibromin 2	2000	0.29
chr16_43423980_43424131	0.32	Gm15713	predicted gene 15713	3859	0.27
chr3_89247265_89247416	0.32	Krtcap2	keratinocyte associated protein 2	906	0.23

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0010046	response to mycotoxin(GO:0010046)
0.2	0.7	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.2	0.5	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.2	0.5	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	0.5	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.4	GO:0045917	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1	0.4	GO:0061535	glutamate secretion, neurotransmission(GO:0061535)
0.1	0.5	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1	0.3	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1	0.6	GO:0006776	vitamin A metabolic process(GO:0006776)
0.1	0.4	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.1	0.5	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	0.3	GO:2000705	regulation of dense core granule biogenesis(GO:2000705)
0.1	0.3	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.3	GO:0031296	B cell costimulation(GO:0031296)
0.1	0.2	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.1	0.3	GO:0015819	lysine transport(GO:0015819)
0.1	0.1	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.1	0.3	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1	0.5	GO:0060613	fat pad development(GO:0060613)
0.1	0.3	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.1	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	0.2	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.1	0.4	GO:1903799	regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798) negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.1	0.3	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.1	0.2	GO:0032513	negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.1	0.2	GO:0001692	histamine metabolic process(GO:0001692)
0.1	0.3	GO:0006526	arginine biosynthetic process(GO:0006526)
0.1	0.2	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	0.2	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.1	0.3	GO:0032482	Rab protein signal transduction(GO:0032482)
0.1	0.2	GO:1900045	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1	0.2	GO:0035935	androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.1	0.2	GO:0051182	coenzyme transport(GO:0051182)
0.1	0.2	GO:0006106	fumarate metabolic process(GO:0006106)
0.1	0.2	GO:1903334	positive regulation of protein folding(GO:1903334)
0.1	0.2	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.1	GO:0097167	circadian regulation of translation(GO:0097167)
0.0	0.2	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.0	0.1	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.0	0.1	GO:0035973	aggrephagy(GO:0035973)
0.0	0.1	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0	0.1	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.2	GO:1902534	single-organism membrane invagination(GO:1902534)
0.0	0.1	GO:0045726	positive regulation of integrin biosynthetic process(GO:0045726)
0.0	0.1	GO:0045914	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.0	0.1	GO:0006068	ethanol catabolic process(GO:0006068)
0.0	0.3	GO:0006228	UTP biosynthetic process(GO:0006228)
0.0	0.2	GO:0006848	pyruvate transport(GO:0006848)
0.0	0.2	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.0	0.2	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0	0.3	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0	0.1	GO:0003383	apical constriction(GO:0003383)
0.0	0.2	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.5	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.3	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.2	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	0.1	GO:0038171	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.2	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.0	0.2	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.2	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.2	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.1	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.1	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.1	GO:0090135	actin filament branching(GO:0090135)
0.0	0.1	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.1	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.1	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.3	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.1	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.0	0.0	GO:0046084	adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.1	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0	0.1	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
0.0	0.9	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.2	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.2	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.3	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.4	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.0	0.1	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0	0.1	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0	0.0	GO:0060331	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.1	GO:0045583	regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0	0.1	GO:0010166	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0	0.2	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.1	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.0	0.1	GO:0060268	negative regulation of respiratory burst(GO:0060268)
0.0	0.1	GO:2000173	negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0	0.1	GO:0046684	response to pyrethroid(GO:0046684)
0.0	0.1	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.1	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.0	0.1	GO:0051031	tRNA transport(GO:0051031)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.2	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.1	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.0	0.1	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0	0.2	GO:0051503	adenine nucleotide transport(GO:0051503)
0.0	0.1	GO:0006059	hexitol metabolic process(GO:0006059)
0.0	0.1	GO:0035627	ceramide transport(GO:0035627)
0.0	0.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.0	0.4	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.1	GO:1902267	polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
0.0	0.1	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.0	0.2	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.1	GO:0021823	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.1	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.0	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.0	0.1	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.1	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.1	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.1	GO:0032364	oxygen homeostasis(GO:0032364)
0.0	0.0	GO:0032056	positive regulation of translation in response to stress(GO:0032056) positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0	0.0	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.3	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.2	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0	0.1	GO:0009730	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:2000637	positive regulation of gene silencing by miRNA(GO:2000637)
0.0	0.1	GO:0045607	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.1	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0	0.0	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.2	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.2	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.1	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.1	GO:0045080	positive regulation of chemokine biosynthetic process(GO:0045080)
0.0	0.0	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.0	0.3	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.2	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.0	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
0.0	0.1	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.1	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.1	GO:0006517	protein deglycosylation(GO:0006517)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.1	GO:0003164	His-Purkinje system development(GO:0003164)
0.0	0.2	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0	0.1	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.1	GO:0035280	miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0	0.1	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0	0.0	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.0	0.1	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0	0.1	GO:0048143	astrocyte activation(GO:0048143)
0.0	0.0	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0019230	proprioception(GO:0019230)
0.0	0.1	GO:0006742	NADP catabolic process(GO:0006742)
0.0	0.0	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.0	0.0	GO:0045764	positive regulation of cellular amino acid metabolic process(GO:0045764)
0.0	0.0	GO:0060416	response to growth hormone(GO:0060416)
0.0	0.1	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.0	0.1	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.0	0.2	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.0	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.2	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.0	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.0	0.1	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.1	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.0	0.0	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
0.0	0.0	GO:2000468	regulation of peroxidase activity(GO:2000468)
0.0	0.0	GO:2000667	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0	0.1	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.1	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.0	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.0	0.1	GO:1900086	regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0	0.0	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.0	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
0.0	0.2	GO:0017144	drug metabolic process(GO:0017144)
0.0	0.1	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.0	0.0	GO:0090310	negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0	0.0	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0	0.0	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.0	GO:1901069	guanosine-containing compound catabolic process(GO:1901069)
0.0	0.0	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.1	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.0	0.1	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.1	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.1	GO:1904729	regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0	0.1	GO:0061038	uterus morphogenesis(GO:0061038)
0.0	0.1	GO:1900107	regulation of nodal signaling pathway(GO:1900107)
0.0	0.0	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.1	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.1	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.0	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.0	GO:0097460	ferrous iron import into cell(GO:0097460)
0.0	0.1	GO:0070445	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0	0.1	GO:0045176	apical protein localization(GO:0045176)
0.0	0.0	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.0	GO:0071280	cellular response to copper ion(GO:0071280)
0.0	0.0	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.1	GO:0002566	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	0.0	GO:0071455	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.0	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.0	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.3	GO:0019432	triglyceride biosynthetic process(GO:0019432)
0.0	0.3	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.1	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.0	GO:0042939	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0	0.0	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0	0.0	GO:0032741	positive regulation of interleukin-18 production(GO:0032741)
0.0	0.0	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.0	0.2	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.1	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
0.0	0.0	GO:0009209	CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.0	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.0	0.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.1	GO:0032308	positive regulation of prostaglandin secretion(GO:0032308)
0.0	0.0	GO:0060300	regulation of cytokine activity(GO:0060300)
0.0	0.0	GO:0071046	polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.0	0.1	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.0	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0	0.2	GO:0042438	melanin biosynthetic process(GO:0042438)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.0	GO:0071503	response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.0	0.1	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.1	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.0	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.0	GO:0034756	regulation of iron ion transport(GO:0034756)
0.0	0.2	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.0	GO:0015770	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.0	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.0	0.1	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.1	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.0	GO:1903242	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0	0.0	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:1903772	regulation of viral budding via host ESCRT complex(GO:1903772)
0.0	0.0	GO:0008105	asymmetric protein localization(GO:0008105)
0.0	0.1	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.0	GO:0046618	drug export(GO:0046618)
0.0	0.0	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.0	GO:0032776	DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776)
0.0	0.0	GO:0060334	regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.2	GO:0042538	hyperosmotic salinity response(GO:0042538)
0.0	0.3	GO:0045739	positive regulation of DNA repair(GO:0045739)
0.0	0.0	GO:0071472	cellular response to salt stress(GO:0071472)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0	0.0	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0	0.0	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
0.0	0.0	GO:0090188	negative regulation of pancreatic juice secretion(GO:0090188)
0.0	0.0	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.0	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.5	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.2	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.1	0.5	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	0.6	GO:0035102	PRC1 complex(GO:0035102)
0.1	0.6	GO:0070852	cell body fiber(GO:0070852)
0.1	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.4	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.2	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.2	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0	0.2	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.2	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.2	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0098536	deuterosome(GO:0098536)
0.0	0.2	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.1	GO:0031298	replication fork protection complex(GO:0031298)
0.0	0.2	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.3	GO:0000346	transcription export complex(GO:0000346)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.1	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.0	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.2	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.2	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.3	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.2	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.3	GO:0043034	costamere(GO:0043034)
0.0	0.0	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.2	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.2	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.1	GO:0097342	ripoptosome(GO:0097342)
0.0	0.2	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.0	0.1	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0	0.0	GO:0005914	spot adherens junction(GO:0005914)
0.0	0.1	GO:0031415	NatA complex(GO:0031415)
0.0	0.0	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.1	GO:0033503	HULC complex(GO:0033503)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.0	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.0	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.0	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.0	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.0	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.2	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.2	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.3	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.0	GO:0045293	mRNA editing complex(GO:0045293)
0.0	0.0	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.1	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.0	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.0	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.4	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.4	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1	0.3	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1	0.5	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1	0.3	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	0.3	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.2	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
0.1	0.4	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.3	GO:0015181	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.1	0.7	GO:0019841	retinol binding(GO:0019841)
0.1	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.4	GO:0045545	syndecan binding(GO:0045545)
0.1	0.2	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.2	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.1	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.3	GO:0043426	MRF binding(GO:0043426)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.2	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.1	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.2	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.0	0.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.1	GO:0031686	A1 adenosine receptor binding(GO:0031686)
0.0	0.5	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.9	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
0.0	0.5	GO:0048038	quinone binding(GO:0048038)
0.0	0.2	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.2	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.2	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.3	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.0	0.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0	0.3	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.1	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.0	0.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.2	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.2	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.2	GO:0045322	unmethylated CpG binding(GO:0045322)
0.0	0.1	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.6	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.4	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
0.0	0.1	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.2	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.0	0.1	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0097001	ceramide binding(GO:0097001)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.4	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.3	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.3	GO:0032942	cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	1.1	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391)
0.0	0.4	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.2	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0019862	IgA binding(GO:0019862)
0.0	0.2	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.3	GO:0070402	NADPH binding(GO:0070402)
0.0	0.0	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.3	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.1	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0	0.2	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.6	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0016453	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0	0.2	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.2	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.2	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.0	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.0	0.3	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.2	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.3	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.0	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.0	0.1	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.2	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.3	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.0	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.0	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.5	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.0	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0	0.1	GO:0004556	alpha-amylase activity(GO:0004556)
0.0	0.1	GO:0032564	dATP binding(GO:0032564)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.1	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0	0.0	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.0	0.0	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.1	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.0	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.2	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.0	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:1990446	U1 snRNP binding(GO:1990446)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.2	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.0	GO:2001070	starch binding(GO:2001070)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.1	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.0	GO:0038100	nodal binding(GO:0038100)
0.0	0.0	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.0	GO:0019959	interleukin-8 binding(GO:0019959)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.0	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.5	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.0	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.0	GO:0070513	death domain binding(GO:0070513)
0.0	0.0	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0	0.3	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.5	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.0	0.0	GO:0016015	morphogen activity(GO:0016015)
0.0	0.2	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.3	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	0.1	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.0	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.0	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.0	GO:0008948	oxaloacetate decarboxylase activity(GO:0008948)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.2	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.0	0.1	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.9	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.7	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.5	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.4	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.4	ST ADRENERGIC	Adrenergic Pathway
0.0	0.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.1	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.0	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.1	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.3	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.0	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.3	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.3	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.3	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.1	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.3	PID FGF PATHWAY	FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.1	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.5	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.0	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.7	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.6	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.7	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.0	REACTOME SIGNAL AMPLIFICATION	Genes involved in Signal amplification
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.5	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.2	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.0	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.2	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.0	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.0	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.1	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.0	REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	Genes involved in Cytokine Signaling in Immune system

Results for Hoxb5

Z-value: 1.99

Motif logo

Transcription factors associated with Hoxb5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Hoxb5 motif across conditions

Conditions sorted by the z-value of the Hoxb5 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: