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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Hoxc10

Z-value: 0.91

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Transcription factors associated with Hoxc10

Gene Symbol	Gene ID	Gene Info
Hoxc10 Ensembl NCBI MGI UniProt	ENSMUSG00000022484.7	Hoxc10

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Hoxc10	chr15_102963900_102964090	2801	0.109164	-0.19	7.2e-01	Click!

Activity of the Hoxc10 motif across conditions

Conditions sorted by the z-value of the Hoxc10 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr13_20205112_20205287	0.52	Elmo1	engulfment and cell motility 1	19992	0.25
chr18_20988207_20988358	0.45	Rnf138	ring finger protein 138	13059	0.19
chr8_123736768_123736919	0.39	Gm45781	predicted gene 45781	1701	0.16
chr16_76237397_76237728	0.37	Nrip1	nuclear receptor interacting protein 1	86096	0.08
chr2_103846113_103846314	0.35	Gm13879	predicted gene 13879	2557	0.13
chr13_93622998_93623302	0.34	Gm15622	predicted gene 15622	2232	0.26
chr12_21190031_21190182	0.32	AC156032.1		57217	0.09
chr3_57605137_57605288	0.30	Mir6377	microRNA 6377	11397	0.12
chr11_82138240_82138391	0.29	Ccl8	chemokine (C-C motif) ligand 8	23130	0.15
chr16_24087119_24087285	0.27	Gm31583	predicted gene, 31583	2887	0.23
chr1_46345449_46345605	0.27	Dnah7b	dynein, axonemal, heavy chain 7B	11093	0.21
chr10_69160830_69160981	0.27	Rhobtb1	Rho-related BTB domain containing 1	9471	0.16
chr3_84231506_84231924	0.27	Trim2	tripartite motif-containing 2	10826	0.24
chr15_26388832_26388991	0.27	Marchf11	membrane associated ring-CH-type finger 11	1192	0.64
chr9_65334133_65334359	0.26	Gm39363	predicted gene, 39363	1726	0.18
chr19_47315824_47316178	0.26	Sh3pxd2a	SH3 and PX domains 2A	1250	0.45
chr12_99342051_99342202	0.26	3300002A11Rik	RIKEN cDNA 3300002A11 gene	972	0.46
chr9_57283258_57283868	0.26	1700017B05Rik	RIKEN cDNA 1700017B05 gene	20951	0.14
chr11_120916572_120916723	0.25	Ccdc57	coiled-coil domain containing 57	16225	0.11
chr16_24394028_24394581	0.25	Lpp	LIM domain containing preferred translocation partner in lipoma	566	0.73
chr3_58583526_58583677	0.25	Selenot	selenoprotein T	6903	0.16
chr15_102245005_102245156	0.25	Rarg	retinoic acid receptor, gamma	151	0.91
chr13_93630762_93631092	0.24	Gm15622	predicted gene 15622	5545	0.17
chr19_30096271_30096642	0.24	Uhrf2	ubiquitin-like, containing PHD and RING finger domains 2	4495	0.24
chr5_30231710_30232189	0.24	Selenoi	selenoprotein I	632	0.63
chr15_31528246_31529049	0.23	Marchf6	membrane associated ring-CH-type finger 6	2406	0.2
chr5_110596813_110596964	0.23	Galnt9	polypeptide N-acetylgalactosaminyltransferase 9	6633	0.15
chr10_24111238_24111394	0.22	Taar9	trace amine-associated receptor 9	1782	0.2
chr18_20931708_20931938	0.22	Rnf125	ring finger protein 125	12802	0.2
chr3_132887148_132887306	0.22	Gm29811	predicted gene, 29811	8631	0.16
chr6_94783873_94784024	0.22	Gm43997	predicted gene, 43997	15484	0.16
chr10_37195063_37195247	0.22	5930403N24Rik	RIKEN cDNA 5930403N24 gene	54066	0.12
chr4_139791597_139791792	0.21	Pax7	paired box 7	41313	0.15
chr13_32797231_32797395	0.21	Wrnip1	Werner helicase interacting protein 1	4725	0.15
chr17_71251888_71252113	0.21	Emilin2	elastin microfibril interfacer 2	3406	0.2
chr7_118304499_118304787	0.21	Gm23229	predicted gene, 23229	24782	0.12
chr7_115868443_115868809	0.20	Sox6	SRY (sex determining region Y)-box 6	8774	0.29
chr19_3831749_3831913	0.20	Gm19209	predicted gene, 19209	9442	0.1
chr6_57726433_57726603	0.20	Lancl2	LanC (bacterial lantibiotic synthetase component C)-like 2	23431	0.12
chr8_119414638_119414789	0.20	Osgin1	oxidative stress induced growth inhibitor 1	19411	0.13
chr14_18234075_18234258	0.20	Nr1d2	nuclear receptor subfamily 1, group D, member 2	4845	0.16
chr19_46983871_46984029	0.20	Nt5c2	5'-nucleotidase, cytosolic II	14382	0.14
chr3_98295816_98295967	0.19	Gm43189	predicted gene 43189	8903	0.15
chr15_80673197_80673348	0.19	Fam83f	family with sequence similarity 83, member F	1425	0.31
chr3_21479148_21479326	0.19	Gm43675	predicted gene 43675	124573	0.06
chr5_139825857_139826025	0.19	Gm26938	predicted gene, 26938	466	0.61
chr3_149086949_149087100	0.19	Gm25127	predicted gene, 25127	58092	0.12
chr12_12320785_12320940	0.19	Fam49a	family with sequence similarity 49, member A	58673	0.14
chr5_25086751_25086975	0.19	Prkag2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	13779	0.15
chr4_120986544_120986936	0.19	Smap2	small ArfGAP 2	11032	0.12
chr1_66895610_66896410	0.19	Gm25832	predicted gene, 25832	29213	0.09
chr6_145355079_145355230	0.18	Gm23498	predicted gene, 23498	11704	0.13
chr8_46540344_46540495	0.18	Acsl1	acyl-CoA synthetase long-chain family member 1	9355	0.15
chr13_90922459_90922719	0.18	Rps23	ribosomal protein S23	369	0.88
chr15_22789821_22790146	0.18	Hnrnpa1l2-ps2	heterogeneous nuclear ribonucleoprotein A1-like 2, pseudogene 2	75153	0.12
chr15_36681116_36681275	0.18	Gm10385	predicted gene 10385	8908	0.14
chr17_30010480_30010631	0.18	Zfand3	zinc finger, AN1-type domain 3	2758	0.19
chr16_95709296_95709447	0.18	Ets2	E26 avian leukemia oncogene 2, 3' domain	3032	0.28
chr8_106882742_106882961	0.18	Chtf8	CTF8, chromosome transmission fidelity factor 8	10364	0.12
chr13_20115696_20115876	0.17	Elmo1	engulfment and cell motility 1	4274	0.33
chr11_99160094_99160256	0.17	Ccr7	chemokine (C-C motif) receptor 7	5098	0.18
chr15_36471981_36472313	0.17	Ankrd46	ankyrin repeat domain 46	24568	0.12
chr11_70648552_70648949	0.17	Rnf167	ring finger protein 167	372	0.59
chr9_108669991_108670142	0.17	Slc25a20	solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20	2430	0.15
chr1_82261807_82261976	0.17	Gm9747	predicted gene 9747	28779	0.15
chr15_74922383_74922543	0.17	Gm6610	predicted gene 6610	1981	0.17
chr15_100112289_100112692	0.17	4930478M13Rik	RIKEN cDNA 4930478M13 gene	4329	0.17
chr4_66018173_66018346	0.16	Gm11484	predicted gene 11484	335590	0.01
chr2_35338418_35338609	0.16	Stom	stomatin	1537	0.27
chr2_36091025_36091199	0.16	Lhx6	LIM homeobox protein 6	3161	0.17
chr6_58832026_58832202	0.16	Herc3	hect domain and RLD 3	253	0.93
chr9_108314669_108314825	0.16	Rhoa	ras homolog family member A	7918	0.07
chr19_26731899_26732052	0.16	Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	1976	0.4
chr4_62966144_62966295	0.16	Zfp618	zinc finger protein 618	645	0.69
chr5_146703840_146704008	0.16	4930573C15Rik	RIKEN cDNA 4930573C15 gene	2698	0.26
chr4_138348310_138348502	0.16	Cda	cytidine deaminase	4757	0.13
chr10_109973597_109973769	0.16	Nav3	neuron navigator 3	26536	0.21
chr15_38471890_38472111	0.16	G930009F23Rik	RIKEN cDNA G930009F23 gene	16866	0.13
chr3_121982194_121982345	0.16	Arhgap29	Rho GTPase activating protein 29	719	0.68
chr1_162301492_162301643	0.15	Dnm3	dynamin 3	5931	0.2
chr7_66077810_66077998	0.15	Gm45081	predicted gene 45081	1569	0.23
chr10_122384642_122385270	0.15	Gm36041	predicted gene, 36041	1936	0.39
chr19_58311318_58311494	0.15	Gm16277	predicted gene 16277	107267	0.07
chr6_50176334_50176508	0.15	Mpp6	membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)	3879	0.27
chr16_48303590_48303752	0.15	Dppa2	developmental pluripotency associated 2	237	0.92
chr8_105825543_105825721	0.15	Ranbp10	RAN binding protein 10	1573	0.19
chr2_156175837_156176038	0.15	Rbm39	RNA binding motif protein 39	1446	0.28
chr2_76673306_76673477	0.15	Fkbp7	FK506 binding protein 7	275	0.87
chr10_31956966_31957141	0.15	Gm18189	predicted gene, 18189	16616	0.27
chr13_34345499_34345841	0.15	Slc22a23	solute carrier family 22, member 23	488	0.8
chr4_141708335_141708559	0.15	Ddi2	DNA-damage inducible protein 2	14972	0.12
chr5_65608952_65609103	0.15	Pds5a	PDS5 cohesin associated factor A	2746	0.14
chr3_83000200_83000478	0.15	Gm30097	predicted gene, 30097	4754	0.17
chr9_32648459_32648646	0.15	Ets1	E26 avian leukemia oncogene 1, 5' domain	12304	0.16
chr2_145813125_145813276	0.15	Rin2	Ras and Rab interactor 2	8950	0.22
chr8_36452309_36452599	0.15	Gm19140	predicted gene, 19140	2074	0.31
chr3_60437847_60438007	0.15	Mbnl1	muscleblind like splicing factor 1	34903	0.19
chr3_65527351_65527507	0.15	4931440P22Rik	RIKEN cDNA 4931440P22 gene	755	0.39
chr10_85161219_85161370	0.15	Cry1	cryptochrome 1 (photolyase-like)	9938	0.18
chr4_61303822_61304309	0.14	Mup14	major urinary protein 14	65	0.97
chr19_3883590_3883781	0.14	Chka	choline kinase alpha	8046	0.08
chr1_170667297_170667480	0.14	Olfml2b	olfactomedin-like 2B	22856	0.16
chr19_42535855_42536113	0.14	R3hcc1l	R3H domain and coiled-coil containing 1 like	17162	0.18
chr13_21395579_21395832	0.14	Mir6942	microRNA 6942	933	0.25
chr12_28905051_28905477	0.14	Gm31508	predicted gene, 31508	4965	0.21
chr12_26125627_26125778	0.14	Gm47750	predicted gene, 47750	24614	0.21
chr12_98375326_98375477	0.14	5330409N07Rik	RIKEN cDNA 5330409N07 gene	72933	0.08
chr19_30095981_30096172	0.14	Uhrf2	ubiquitin-like, containing PHD and RING finger domains 2	4115	0.24
chr3_100785704_100785863	0.14	Vtcn1	V-set domain containing T cell activation inhibitor 1	39676	0.14
chr8_35413438_35413609	0.14	Gm45301	predicted gene 45301	4017	0.2
chr11_67516560_67516876	0.14	Gas7	growth arrest specific 7	30436	0.19
chr2_157556257_157556418	0.14	Blcap	bladder cancer associated protein	3670	0.14
chr15_10712881_10713032	0.14	Rai14	retinoic acid induced 14	584	0.71
chr7_113778913_113779066	0.14	Spon1	spondin 1, (f-spondin) extracellular matrix protein	12815	0.22
chr4_33223953_33224209	0.14	Srsf12	serine and arginine-rich splicing factor 12	14818	0.14
chr14_20315223_20315409	0.14	Nudt13	nudix (nucleoside diphosphate linked moiety X)-type motif 13	3887	0.15
chr2_145727998_145728180	0.14	Gm11763	predicted gene 11763	26364	0.18
chr16_6592226_6592401	0.14	Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1	216909	0.02
chr15_78913574_78913725	0.13	1700027A07Rik	RIKEN cDNA 1700027A07 gene	11	0.77
chr18_9632745_9632896	0.13	Gm4834	predicted gene 4834	3958	0.16
chr17_45566033_45566184	0.13	Slc35b2	solute carrier family 35, member B2	1369	0.23
chr19_33099137_33099698	0.13	Gm29946	predicted gene, 29946	23230	0.18
chr8_128363089_128363260	0.13	Nrp1	neuropilin 1	3777	0.26
chr13_17717656_17717837	0.13	Gm48621	predicted gene, 48621	7882	0.12
chr6_114936968_114937119	0.13	Vgll4	vestigial like family member 4	15222	0.21
chr9_22314126_22314292	0.13	Zfp810	zinc finger protein 810	6561	0.09
chr11_45872012_45872204	0.13	Clint1	clathrin interactor 1	10289	0.16
chr1_191480561_191480712	0.13	Gm37688	predicted gene, 37688	3305	0.18
chr16_26733286_26733437	0.13	Il1rap	interleukin 1 receptor accessory protein	6319	0.26
chr5_89012654_89012806	0.13	Slc4a4	solute carrier family 4 (anion exchanger), member 4	15236	0.27
chr12_99537214_99537482	0.13	Foxn3	forkhead box N3	26160	0.12
chr1_121332181_121332567	0.13	Insig2	insulin induced gene 2	176	0.94
chr15_91608960_91609149	0.13	4933438A12Rik	RIKEN cDNA 4933438A12 gene	11471	0.18
chr5_36177248_36177418	0.13	Psapl1	prosaposin-like 1	26688	0.22
chr4_90616833_90616984	0.13	Gm12636	predicted gene 12636	72538	0.12
chr18_20671827_20672076	0.13	Ttr	transthyretin	6671	0.17
chr5_135741186_135741337	0.13	Tmem120a	transmembrane protein 120A	1138	0.32
chr18_38312030_38312222	0.13	Rnf14	ring finger protein 14	12374	0.1
chr19_29370028_29370202	0.13	Cd274	CD274 antigen	2660	0.18
chr8_45529825_45529981	0.13	Gm45458	predicted gene 45458	10212	0.18
chr19_21824245_21824555	0.13	Gm50130	predicted gene, 50130	9356	0.22
chr19_17159808_17159970	0.13	Prune2	prune homolog 2	21150	0.22
chr16_35919055_35919394	0.13	Gm10237	predicted gene 10237	1240	0.32
chr11_77728722_77728873	0.13	Cryba1	crystallin, beta A1	3514	0.17
chr1_24743279_24743468	0.13	Lmbrd1	LMBR1 domain containing 1	1500	0.46
chr9_111209525_111209710	0.13	Lrrfip2	leucine rich repeat (in FLII) interacting protein 2	4576	0.2
chr19_23961632_23961790	0.13	Fam189a2	family with sequence similarity 189, member A2	14724	0.16
chr4_139974069_139974220	0.13	Klhdc7a	kelch domain containing 7A	6118	0.17
chr11_101369874_101370035	0.13	G6pc	glucose-6-phosphatase, catalytic	2393	0.1
chr6_98954486_98954663	0.13	Foxp1	forkhead box P1	19029	0.26
chr2_122887240_122887411	0.13	Sqor	sulfide quinone oxidoreductase	87563	0.08
chr7_49488722_49488898	0.13	Gm38059	predicted gene, 38059	19098	0.22
chr3_79549707_79549864	0.13	Gm3513	predicted gene 3513	2408	0.21
chr17_50515527_50515699	0.13	Plcl2	phospholipase C-like 2	6210	0.31
chr4_33292661_33293055	0.13	Pnrc1	proline-rich nuclear receptor coactivator 1	2695	0.24
chr2_170128598_170128786	0.13	Zfp217	zinc finger protein 217	2528	0.4
chr14_121181940_121182118	0.13	B930095G15Rik	RIKEN cDNA B930095G15 gene	66677	0.11
chr11_20829675_20830062	0.12	Lgalsl	lectin, galactoside binding-like	887	0.49
chr4_20032087_20032276	0.12	Ggh	gamma-glutamyl hydrolase	9871	0.2
chr5_131017810_131017961	0.12	Gm43165	predicted gene 43165	25085	0.21
chrX_170004028_170004179	0.12	Erdr1	erythroid differentiation regulator 1	5556	0.17
chr4_104530575_104530756	0.12	Dab1	disabled 1	18592	0.29
chr10_59786230_59786381	0.12	Gm17059	predicted gene 17059	13949	0.14
chr11_102744260_102744413	0.12	Gm16342	predicted gene 16342	11931	0.11
chr15_25650294_25650463	0.12	Gm48996	predicted gene, 48996	15751	0.17
chr14_22817406_22817579	0.12	Gm7473	predicted gene 7473	42248	0.2
chr4_86686025_86686176	0.12	Plin2	perilipin 2	16040	0.18
chrY_90775341_90775665	0.12	Gm47283	predicted gene, 47283	9235	0.17
chr4_88184310_88184469	0.12	Gm12645	predicted gene 12645	32693	0.16
chr15_81798335_81798552	0.12	Tef	thyrotroph embryonic factor	3978	0.12
chr10_91170398_91170640	0.12	Tmpo	thymopoietin	57	0.97
chr11_31897693_31897844	0.12	Cpeb4	cytoplasmic polyadenylation element binding protein 4	24493	0.18
chr5_41572654_41572805	0.12	Rab28	RAB28, member RAS oncogene family	54773	0.16
chr2_30163705_30163866	0.12	Slc39a1-ps	solute carrier family 39 (zinc transporter), member 1, pseudogene	4387	0.11
chr13_32823696_32823847	0.12	Wrnip1	Werner helicase interacting protein 1	3005	0.19
chr11_106982284_106982435	0.12	Gm11707	predicted gene 11707	9269	0.13
chr17_63491587_63491744	0.12	Fbxl17	F-box and leucine-rich repeat protein 17	1088	0.61
chr8_128687218_128687546	0.12	Itgb1	integrin beta 1 (fibronectin receptor beta)	1512	0.39
chr2_103801242_103801527	0.12	Caprin1	cell cycle associated protein 1	3735	0.12
chr7_127973702_127973919	0.12	Fus	fused in sarcoma	333	0.72
chrY_90764765_90764916	0.12	Gm21860	predicted gene, 21860	9373	0.17
chr12_21183631_21184095	0.12	AC156032.1		63460	0.08
chrX_169990489_169990640	0.12	Gm15247	predicted gene 15247	3625	0.18
chr4_44997538_44997819	0.12	1700055D18Rik	RIKEN cDNA 1700055D18 gene	14009	0.1
chrX_170001003_170001326	0.12	Erdr1	erythroid differentiation regulator 1	8495	0.15
chr4_53414447_53414950	0.12	Gm12496	predicted gene 12496	10668	0.21
chr11_95726300_95726491	0.12	Zfp652	zinc finger protein 652	13384	0.12
chr4_153239041_153239351	0.12	Gm13174	predicted gene 13174	21020	0.26
chr16_18430516_18430667	0.12	Txnrd2	thioredoxin reductase 2	1666	0.22
chr1_134580810_134580961	0.12	Kdm5b	lysine (K)-specific demethylase 5B	7092	0.15
chr4_139169377_139169633	0.12	Gm16287	predicted gene 16287	11150	0.13
chr4_145215459_145215632	0.12	Vps13d	vacuolar protein sorting 13D	20540	0.19
chr1_88975960_88976113	0.12	1700067G17Rik	RIKEN cDNA 1700067G17 gene	40077	0.14
chr13_95794713_95795054	0.12	Iqgap2	IQ motif containing GTPase activating protein 2	30486	0.16
chr6_54772634_54772785	0.12	Znrf2	zinc and ring finger 2	44207	0.14
chr5_92867642_92867801	0.12	Shroom3	shroom family member 3	11250	0.22
chr11_94383447_94383613	0.12	Abcc3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	9390	0.16
chr15_102245839_102245990	0.12	Rarg	retinoic acid receptor, gamma	586	0.56
chr18_46711768_46711921	0.11	Cdo1	cysteine dioxygenase 1, cytosolic	16185	0.12
chr1_121320571_121320766	0.11	Insig2	insulin induced gene 2	940	0.52

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxc10

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0070384	Harderian gland development(GO:0070384)
0.0	0.1	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.1	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.0	0.1	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.1	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.2	GO:0006991	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.1	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.1	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0	0.2	GO:0071267	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.1	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.0	0.1	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.1	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.1	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.1	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.0	0.1	GO:0009093	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0	0.1	GO:0040038	polar body extrusion after meiotic divisions(GO:0040038)
0.0	0.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.1	GO:0008050	female courtship behavior(GO:0008050)
0.0	0.1	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.1	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.0	0.1	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.0	GO:2000410	thymocyte migration(GO:0072679) regulation of thymocyte migration(GO:2000410) positive regulation of thymocyte migration(GO:2000412)
0.0	0.1	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.0	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.0	0.0	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.0	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.0	0.0	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.0	GO:2000850	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0	0.1	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.0	GO:0061642	chemoattraction of axon(GO:0061642)
0.0	0.0	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.0	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0	0.1	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.0	0.0	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
0.0	0.1	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.0	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.0	0.1	GO:0030953	astral microtubule organization(GO:0030953)
0.0	0.0	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0006172	ADP biosynthetic process(GO:0006172)
0.0	0.1	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.0	GO:0010909	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.0	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0	0.0	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.0	0.0	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.0	0.0	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0	0.0	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.0	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0	0.1	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.1	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0	0.1	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.0	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.0	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.0	0.0	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.0	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.0	0.0	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.0	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.0	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.0	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0009279	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.0	GO:0097443	sorting endosome(GO:0097443)
0.0	0.0	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.0	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.0	GO:0000172	ribonuclease MRP complex(GO:0000172)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.3	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0033142	progesterone receptor binding(GO:0033142)
0.0	0.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.1	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.1	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	0.1	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.0	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.0	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.0	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.0	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.1	GO:0035473	lipase binding(GO:0035473)
0.0	0.0	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.0	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.0	GO:0019961	interferon binding(GO:0019961)
0.0	0.0	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0042910	xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.0	0.0	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.1	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway