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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Hoxc6

Z-value: 1.05

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Transcription factors associated with Hoxc6

Gene Symbol Gene ID Gene Info
Hoxc6
ENSMUSG00000001661.4 homeobox C6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr15_102999275_102999447Hoxc611040.276127-0.354.9e-01Click!

Activity of the Hoxc6 motif across conditions

Conditions sorted by the z-value of the Hoxc6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_9968620_9968771 0.65 Tcf24
 transcription factor 24
 763
 0.41
chr19_39287276_39287531 0.58 Cyp2c29
 cytochrome P450, family 2, subfamily c, polypeptide 29
 329
 0.91
chr2_60118945_60119257 0.57 Gm13620
 predicted gene 13620
 5995
 0.16
chr7_104995535_104995703 0.54 Olfr672
 olfactory receptor 672
 1283
 0.2
chr5_29596501_29596658 0.53 Ube3c
 ubiquitin protein ligase E3C
 5750
 0.22
chr8_45341558_45341748 0.53 Cyp4v3
 cytochrome P450, family 4, subfamily v, polypeptide 3
 8437
 0.15
chr2_134491985_134492278 0.52 Hao1
 hydroxyacid oxidase 1, liver
 62176
 0.15
chr4_47366562_47366857 0.52 Tgfbr1
 transforming growth factor, beta receptor I
 13099
 0.22
chr6_108281132_108281339 0.52 Itpr1
 inositol 1,4,5-trisphosphate receptor 1
 28277
 0.22
chr11_28696545_28697113 0.50 2810471M01Rik
 RIKEN cDNA 2810471M01 gene
 15265
 0.17
chr2_131345745_131345918 0.47 Rnf24
 ring finger protein 24
 7031
 0.14
chr13_119432132_119432318 0.42 Paip1
 polyadenylate binding protein-interacting protein 1
 3067
 0.2
chr2_130932638_130932843 0.41 Atrn
 attractin
 25809
 0.11
chr13_34626488_34626639 0.41 Gm47127
 predicted gene, 47127
 14317
 0.13
chr3_117078471_117078622 0.39 1700061I17Rik
 RIKEN cDNA 1700061I17 gene
 781
 0.64
chr19_37323790_37323978 0.37 Ide
 insulin degrading enzyme
 6729
 0.16
chr10_88719373_88719562 0.36 Gm48144
 predicted gene, 48144
 3373
 0.12
chr1_188125975_188126247 0.36 Gm38315
 predicted gene, 38315
 34596
 0.21
chr13_102570134_102570306 0.36 Gm29927
 predicted gene, 29927
 20065
 0.22
chr5_21175987_21176254 0.35 Gsap
 gamma-secretase activating protein
 10135
 0.15
chr17_35590917_35591091 0.35 Sfta2
 surfactant associated 2
 10545
 0.08
chr1_100298746_100298897 0.35 Gm29667
 predicted gene 29667
 16030
 0.18
chr15_3533289_3533452 0.33 Ghr
 growth hormone receptor
 48472
 0.16
chr4_88893074_88893256 0.33 Ifne
 interferon epsilon
 12964
 0.08
chr9_42461424_42462009 0.33 Tbcel
 tubulin folding cofactor E-like
 255
 0.91
chr3_138287619_138288216 0.33 Adh1
 alcohol dehydrogenase 1 (class I)
 10266
 0.12
chr6_100204562_100204726 0.33 Rybp
 RING1 and YY1 binding protein
 28487
 0.15
chr15_60694082_60694233 0.32 Gm23835
 predicted gene, 23835
 9966
 0.19
chr13_95772378_95772529 0.32 Iqgap2
 IQ motif containing GTPase activating protein 2
 8056
 0.19
chr11_115459206_115459357 0.31 Slc16a5
 solute carrier family 16 (monocarboxylic acid transporters), member 5
 3193
 0.1
chr7_120604351_120604519 0.31 E130201H02Rik
 RIKEN cDNA E130201H02 gene
 6810
 0.11
chr2_168734428_168734613 0.31 Atp9a
 ATPase, class II, type 9A
 181
 0.95
chr10_95354659_95354831 0.31 2310039L15Rik
 RIKEN cDNA 2310039L15 gene
 143
 0.94
chr16_93873807_93873958 0.30 Chaf1b
 chromatin assembly factor 1, subunit B (p60)
 10019
 0.13
chr19_12771696_12771894 0.30 Cntf
 ciliary neurotrophic factor
 6163
 0.12
chr15_32923240_32923575 0.30 Sdc2
 syndecan 2
 2684
 0.39
chr4_131882954_131883105 0.29 Srsf4
 serine and arginine-rich splicing factor 4
 1266
 0.29
chr3_60097884_60098081 0.29 Sucnr1
 succinate receptor 1
 16080
 0.18
chr16_56714341_56714503 0.29 Tfg
 Trk-fused gene
 1446
 0.47
chr13_9077339_9077490 0.29 Gm36264
 predicted gene, 36264
 963
 0.5
chr13_95811525_95811676 0.28 Iqgap2
 IQ motif containing GTPase activating protein 2
 47203
 0.13
chr11_43783562_43783743 0.28 Ttc1
 tetratricopeptide repeat domain 1
 35644
 0.16
chr2_155583504_155583661 0.28 Gss
 glutathione synthetase
 920
 0.33
chr12_36155790_36155945 0.27 Bzw2
 basic leucine zipper and W2 domains 2
 760
 0.46
chr4_10835624_10835785 0.27 Mir3471-1
 microRNA 3471-1
 9926
 0.12
chr19_41244661_41244826 0.27 Tm9sf3
 transmembrane 9 superfamily member 3
 19237
 0.21
chr5_7964334_7964518 0.27 Steap4
 STEAP family member 4
 3969
 0.19
chr9_108309327_108309485 0.27 Rhoa
 ras homolog family member A
 2577
 0.11
chr3_5425056_5425268 0.27 4930555M17Rik
 RIKEN cDNA 4930555M17 gene
 90171
 0.09
chr1_185370452_185370690 0.27 Eprs
 glutamyl-prolyl-tRNA synthetase
 2974
 0.15
chr13_41219562_41219715 0.27 Elovl2
 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2
 524
 0.68
chr2_50284584_50284735 0.27 Mmadhc
 methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
 4540
 0.25
chr2_35060101_35060327 0.26 Hc
 hemolytic complement
 1224
 0.43
chr5_90315666_90315817 0.26 Ankrd17
 ankyrin repeat domain 17
 11637
 0.21
chr4_106354190_106354378 0.26 Usp24
 ubiquitin specific peptidase 24
 38050
 0.13
chr17_81386388_81386573 0.26 Gm50044
 predicted gene, 50044
 15647
 0.24
chr17_47923114_47923463 0.26 Gm15556
 predicted gene 15556
 910
 0.38
chr16_30386539_30386690 0.25 Atp13a3
 ATPase type 13A3
 1871
 0.37
chr6_67268305_67268456 0.25 Serbp1
 serpine1 mRNA binding protein 1
 1050
 0.44
chr12_78218868_78219034 0.25 Gphn
 gephyrin
 7428
 0.15
chr1_72583626_72583816 0.25 Smarcal1
 SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
 106
 0.97
chr1_139780384_139780535 0.25 Gm4788
 predicted gene 4788
 709
 0.69
chr2_64079562_64079736 0.25 Fign
 fidgetin
 18339
 0.3
chr13_101760313_101760479 0.25 Gm36638
 predicted gene, 36638
 7191
 0.21
chr3_75530671_75531016 0.25 Pdcd10
 programmed cell death 10
 9273
 0.2
chr2_48403972_48404299 0.25 Gm13472
 predicted gene 13472
 16098
 0.2
chr7_70483265_70483615 0.25 Gm7656
 predicted gene 7656
 7408
 0.16
chr18_43131844_43132003 0.24 Gm8181
 predicted gene 8181
 39236
 0.13
chr7_136914047_136914226 0.24 Gm45280
 predicted gene 45280
 6805
 0.24
chr12_73855812_73855997 0.24 Gm15283
 predicted gene 15283
 13708
 0.17
chr1_160996279_160996443 0.24 Gm37072
 predicted gene, 37072
 5484
 0.07
chr13_97927511_97927679 0.24 Arhgef28
 Rho guanine nucleotide exchange factor (GEF) 28
 19332
 0.21
chr11_53418931_53419109 0.24 Leap2
 liver-expressed antimicrobial peptide 2
 4150
 0.1
chr7_100907329_100907491 0.24 Arhgef17
 Rho guanine nucleotide exchange factor (GEF) 17
 12720
 0.14
chr10_53113782_53113941 0.24 Gm47622
 predicted gene, 47622
 11318
 0.22
chr2_132853961_132854112 0.24 Crls1
 cardiolipin synthase 1
 6298
 0.14
chr3_51437862_51438013 0.24 Naa15
 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
 2980
 0.14
chr8_116404224_116404375 0.24 1700018P08Rik
 RIKEN cDNA 1700018P08 gene
 47238
 0.17
chr13_117508625_117508817 0.24 Gm5200
 predicted gene 5200
 49646
 0.17
chr16_4772912_4773063 0.24 Cdip1
 cell death inducing Trp53 target 1
 1475
 0.28
chr2_71498544_71498972 0.24 Gm23253
 predicted gene, 23253
 3487
 0.17
chr10_108979346_108979586 0.24 Gm47477
 predicted gene, 47477
 22978
 0.22
chr19_56171122_56171273 0.23 Gm31912
 predicted gene, 31912
 64887
 0.11
chr14_114123652_114123812 0.23 Gm18369
 predicted gene, 18369
 48711
 0.19
chr2_145233540_145233706 0.23 Slc24a3
 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
 8988
 0.28
chr10_87831885_87832059 0.23 Igf1os
 insulin-like growth factor 1, opposite strand
 3610
 0.27
chr3_135510262_135510447 0.23 Manba
 mannosidase, beta A, lysosomal
 6796
 0.13
chr18_61422291_61422459 0.23 Gm8755
 predicted gene 8755
 11826
 0.12
chr12_40608115_40608266 0.23 Dock4
 dedicator of cytokinesis 4
 161854
 0.03
chr16_17340724_17340946 0.23 Gm24927
 predicted gene, 24927
 1177
 0.36
chr2_5968425_5968579 0.23 Upf2
 UPF2 regulator of nonsense transcripts homolog (yeast)
 17033
 0.17
chr6_117059962_117060118 0.23 Gm43929
 predicted gene, 43929
 78021
 0.08
chr15_97247773_97248330 0.23 Amigo2
 adhesion molecule with Ig like domain 2
 764
 0.48
chr2_91378186_91378346 0.23 Gm22071
 predicted gene, 22071
 28870
 0.13
chr9_122138979_122139323 0.23 Gm47121
 predicted gene, 47121
 3298
 0.16
chr4_82378492_82378694 0.23 n-R5s188
 nuclear encoded rRNA 5S 188
 60817
 0.14
chr19_42150846_42151168 0.22 Marveld1
 MARVEL (membrane-associating) domain containing 1
 3299
 0.14
chr12_54967535_54967800 0.22 Gm27014
 predicted gene, 27014
 4603
 0.15
chr11_49260229_49260441 0.22 Mgat1
 mannoside acetylglucosaminyltransferase 1
 4091
 0.14
chr3_138430699_138430859 0.22 Adh5
 alcohol dehydrogenase 5 (class III), chi polypeptide
 12314
 0.12
chr8_61273697_61273901 0.22 1700001D01Rik
 RIKEN cDNA 1700001D01 gene
 15073
 0.2
chr15_3482890_3483092 0.22 Ghr
 growth hormone receptor
 11347
 0.28
chr12_7816660_7817001 0.22 Gm32828
 predicted gene, 32828
 42861
 0.14
chr6_141613801_141613980 0.22 Slco1b2
 solute carrier organic anion transporter family, member 1b2
 15628
 0.25
chr19_40154709_40154860 0.22 Cyp2c70
 cytochrome P450, family 2, subfamily c, polypeptide 70
 32502
 0.13
chr10_124590350_124590536 0.22 4930503E24Rik
 RIKEN cDNA 4930503E24 gene
 67005
 0.14
chr11_72631760_72631911 0.22 Gm24143
 predicted gene, 24143
 15685
 0.13
chr2_15056785_15057135 0.21 Gm38257
 predicted gene, 38257
 247
 0.86
chr2_130908138_130908309 0.21 Atrn
 attractin
 1292
 0.28
chr1_102517589_102517767 0.21 Gm20281
 predicted gene, 20281
 58756
 0.14
chr17_33667328_33667604 0.21 Hnrnpm
 heterogeneous nuclear ribonucleoprotein M
 896
 0.43
chr10_115511796_115512121 0.21 Lgr5
 leucine rich repeat containing G protein coupled receptor 5
 48879
 0.12
chr1_57342831_57342992 0.21 4930558J18Rik
 RIKEN cDNA 4930558J18 gene
 34633
 0.12
chr8_41096211_41096362 0.21 Mtus1
 mitochondrial tumor suppressor 1
 13510
 0.18
chr12_7948991_7949142 0.21 Gm48633
 predicted gene, 48633
 995
 0.56
chr6_95003514_95003791 0.21 4930511E03Rik
 RIKEN cDNA 4930511E03 gene
 59818
 0.12
chr10_4333753_4333924 0.21 Akap12
 A kinase (PRKA) anchor protein (gravin) 12
 707
 0.68
chr4_72166936_72167097 0.21 Gm11250
 predicted gene 11250
 1752
 0.4
chr4_76363527_76363872 0.21 Ptprd
 protein tyrosine phosphatase, receptor type, D
 19456
 0.22
chr16_26702287_26702472 0.21 Il1rap
 interleukin 1 receptor accessory protein
 20055
 0.24
chr13_64099099_64099277 0.21 Slc35d2
 solute carrier family 35, member D2
 7975
 0.15
chr7_25448767_25449204 0.21 Gm15495
 predicted gene 15495
 5522
 0.11
chr10_29019588_29019757 0.21 Gm9824
 predicted pseudogene 9824
 10456
 0.14
chr18_33210537_33210688 0.20 Stard4
 StAR-related lipid transfer (START) domain containing 4
 3154
 0.37
chr13_44432624_44432823 0.20 1700029N11Rik
 RIKEN cDNA 1700029N11 gene
 6989
 0.16
chr19_31886956_31887132 0.20 A1cf
 APOBEC1 complementation factor
 18263
 0.2
chr9_100619847_100620182 0.20 Gm8661
 predicted gene 8661
 5951
 0.15
chr5_23441774_23441951 0.20 Kmt2e
 lysine (K)-specific methyltransferase 2E
 7413
 0.15
chr5_65431439_65431654 0.20 Gm43289
 predicted gene 43289
 34
 0.95
chr5_106573979_106574163 0.20 Gm28050
 predicted gene, 28050
 644
 0.46
chr15_3469696_3469847 0.20 Ghr
 growth hormone receptor
 1873
 0.48
chr3_18166354_18166574 0.20 Gm23686
 predicted gene, 23686
 11161
 0.24
chr13_4192623_4192780 0.20 Akr1c13
 aldo-keto reductase family 1, member C13
 1157
 0.38
chr14_14071519_14071682 0.20 Atxn7
 ataxin 7
 15869
 0.17
chr15_11190225_11190388 0.20 Adamts12
 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12
 125488
 0.05
chr3_149318468_149318647 0.20 Gm30382
 predicted gene, 30382
 5317
 0.21
chr4_132930929_132931084 0.20 Gm24913
 predicted gene, 24913
 311
 0.85
chr16_42999237_42999415 0.20 Ndufs5-ps
 NADH:ubiquinone oxidoreductase core subunit S5, pseudogene
 43695
 0.16
chr2_40479361_40479517 0.19 Gm13456
 predicted gene 13456
 76313
 0.11
chr6_54035175_54035554 0.19 Chn2
 chimerin 2
 4190
 0.24
chr1_67091897_67092231 0.19 Cps1
 carbamoyl-phosphate synthetase 1
 30962
 0.17
chr18_51157676_51157865 0.19 Prr16
 proline rich 16
 40032
 0.21
chr12_7751611_7751762 0.19 Gm32828
 predicted gene, 32828
 108005
 0.06
chr7_14529256_14529446 0.19 Obox4-ps2
 oocyte specific homeobox 4, pseudogene 2
 715
 0.53
chr16_43403257_43403418 0.19 Gm15713
 predicted gene 15713
 16859
 0.18
chr7_100609531_100609682 0.19 Mrpl48
 mitochondrial ribosomal protein L48
 1305
 0.26
chr3_60515813_60516054 0.19 Mbnl1
 muscleblind like splicing factor 1
 12195
 0.22
chr15_3570914_3571065 0.19 Ghr
 growth hormone receptor
 10853
 0.25
chr6_47814259_47814426 0.19 Pdia4
 protein disulfide isomerase associated 4
 912
 0.35
chr18_39503638_39503872 0.19 Nr3c1
 nuclear receptor subfamily 3, group C, member 1
 12454
 0.26
chr11_52351256_52351613 0.19 Vdac1
 voltage-dependent anion channel 1
 9426
 0.17
chr2_130058269_130058427 0.19 Gm22424
 predicted gene, 22424
 13376
 0.13
chr12_79436402_79436553 0.19 Rad51b
 RAD51 paralog B
 109124
 0.06
chr1_21261382_21261702 0.19 Gsta3
 glutathione S-transferase, alpha 3
 8021
 0.11
chr12_57441896_57442047 0.19 Gm16246
 predicted gene 16246
 8149
 0.23
chr7_70365214_70365757 0.19 B130024G19Rik
 RIKEN cDNA B130024G19 gene
 326
 0.78
chr9_75037221_75037495 0.19 Arpp19
 cAMP-regulated phosphoprotein 19
 256
 0.91
chrX_93630327_93630494 0.19 Pola1
 polymerase (DNA directed), alpha 1
 1705
 0.34
chr9_72288048_72288199 0.19 Gm19353
 predicted gene, 19353
 1544
 0.21
chr13_95786097_95786248 0.19 Iqgap2
 IQ motif containing GTPase activating protein 2
 21775
 0.18
chr16_91678296_91678553 0.19 Donson
 downstream neighbor of SON
 2886
 0.15
chr11_95365489_95365701 0.19 Fam117a
 family with sequence similarity 117, member A
 9872
 0.12
chr15_36496930_36497165 0.19 Ankrd46
 ankyrin repeat domain 46
 227
 0.91
chr6_14897077_14897293 0.19 Foxp2
 forkhead box P2
 4164
 0.36
chr1_56623913_56624064 0.19 Hsfy2
 heat shock transcription factor, Y-linked 2
 13447
 0.28
chr5_42887251_42887423 0.18 Gm5554
 predicted gene 5554
 77272
 0.11
chr12_45069728_45070323 0.18 Stxbp6
 syntaxin binding protein 6 (amisyn)
 4087
 0.24
chr9_111124362_111124513 0.18 Lrrfip2
 leucine rich repeat (in FLII) interacting protein 2
 4762
 0.17
chr7_72247872_72248068 0.18 Mctp2
 multiple C2 domains, transmembrane 2
 18610
 0.26
chr1_158541726_158541892 0.18 Gm37367
 predicted gene, 37367
 7002
 0.15
chr1_156558196_156558347 0.18 Abl2
 v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
 515
 0.76
chr9_122148160_122148327 0.18 Gm47121
 predicted gene, 47121
 5794
 0.13
chr18_59092890_59093288 0.18 Minar2
 membrane integral NOTCH2 associated receptor 2
 30578
 0.22
chr10_44766057_44766218 0.18 4930431F10Rik
 RIKEN cDNA 4930431F10 gene
 27237
 0.12
chr10_69104876_69105058 0.18 Gm47107
 predicted gene, 47107
 7101
 0.19
chr5_134311252_134311463 0.18 Gtf2i
 general transcription factor II I
 370
 0.8
chr5_86888528_86888722 0.18 Ugt2b34
 UDP glucuronosyltransferase 2 family, polypeptide B34
 18312
 0.1
chr6_24610042_24610446 0.18 Lmod2
 leiomodin 2 (cardiac)
 12482
 0.14
chr9_20581625_20581828 0.18 Zfp846
 zinc finger protein 846
 194
 0.9
chr8_68008523_68008836 0.18 Gm22018
 predicted gene, 22018
 1661
 0.43
chr7_118571834_118571985 0.18 Tmc7
 transmembrane channel-like gene family 7
 5282
 0.16
chr4_84545854_84546088 0.18 Bnc2
 basonuclin 2
 319
 0.94
chr4_6923149_6923300 0.18 Tox
 thymocyte selection-associated high mobility group box
 67259
 0.13
chr2_84727873_84728024 0.18 Clp1
 CLP1, cleavage and polyadenylation factor I subunit
 598
 0.5
chr11_116501017_116501181 0.18 Rpl36-ps1
 ribosomal protein L36, pseudogene 1
 3437
 0.12
chr1_31097093_31097258 0.18 4931428L18Rik
 RIKEN cDNA 4931428L18 gene
 721
 0.62
chr17_4944661_4944832 0.18 Gm41517
 predicted gene, 41517
 2068
 0.36
chr11_28698214_28698534 0.18 2810471M01Rik
 RIKEN cDNA 2810471M01 gene
 16810
 0.16
chr18_43845253_43845404 0.18 Gm41715
 predicted gene, 41715
 5232
 0.18
chr10_41886623_41887088 0.17 Sesn1
 sestrin 1
 584
 0.78
chr14_117733261_117733423 0.17 Mir6239
 microRNA 6239
 220505
 0.02
chr6_27753809_27753967 0.17 Gm26310
 predicted gene, 26310
 85801
 0.1
chr5_121431395_121431558 0.17 Naa25
 N(alpha)-acetyltransferase 25, NatB auxiliary subunit
 7942
 0.1
chr15_76314416_76314716 0.17 Oplah
 5-oxoprolinase (ATP-hydrolysing)
 4811
 0.07
chr10_67176584_67176792 0.17 Jmjd1c
 jumonji domain containing 1C
 9060
 0.22
chrX_152327737_152327888 0.17 Kantr
 Kdm5c adjacent non-coding transcript
 317
 0.85
chr4_70517804_70518135 0.17 Megf9
 multiple EGF-like-domains 9
 16959
 0.29
chrX_166458575_166458751 0.17 Trappc2
 trafficking protein particle complex 2
 13360
 0.13
chr1_9989244_9989423 0.17 Ppp1r42
 protein phosphatase 1, regulatory subunit 42
 3641
 0.12
chr18_6514098_6514308 0.17 Epc1
 enhancer of polycomb homolog 1
 1905
 0.3

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxc6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0072338 creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1 0.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.3 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.0 0.1 GO:2000302 positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.1 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.0 0.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.0 GO:0006069 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.1 GO:0061724 lipophagy(GO:0061724)
0.0 0.1 GO:0035523 protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0060375 regulation of mast cell differentiation(GO:0060375)
0.0 0.2 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.0 0.1 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.6 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.0 0.0 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.0 0.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0 0.0 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0 0.0 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0033216 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.0 0.0 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.0 GO:0043366 beta selection(GO:0043366)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.0 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.0 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0 0.1 GO:0097070 ductus arteriosus closure(GO:0097070)
0.0 0.0 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.0 GO:0032789 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0 0.0 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.0 0.0 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.0 0.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.0 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0 0.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.0 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.0 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.1 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 0.0 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.1 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 0.1 GO:0098596 vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.0 0.0 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.1 GO:2000370 positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0 0.1 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0 0.0 GO:0015677 copper ion import(GO:0015677)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.0 GO:0009202 deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.0 0.0 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.0 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 0.0 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:0070989 oxidative demethylation(GO:0070989)
0.0 0.0 GO:0010963 regulation of L-arginine import(GO:0010963)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.0 GO:0070948 regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.0 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.1 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.0 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.0 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.0 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.0 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.0 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.0 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.0 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0045293 mRNA editing complex(GO:0045293)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.0 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.0 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.2 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.2 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.0 GO:0035276 ethanol binding(GO:0035276)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.0 0.1 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.0 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.0 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.0 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0018631 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.0 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin