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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Hoxc9

Z-value: 1.88

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Transcription factors associated with Hoxc9

Gene Symbol Gene ID Gene Info
Hoxc9
ENSMUSG00000036139.6 homeobox C9

Activity of the Hoxc9 motif across conditions

Conditions sorted by the z-value of the Hoxc9 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_47699832_47699983 1.65 Gm50281
 predicted gene, 50281
 3374
 0.13
chr15_103305267_103305425 1.19 Gm49482
 predicted gene, 49482
 4281
 0.11
chr2_26487761_26487912 1.12 Notch1
 notch 1
 15986
 0.09
chr13_103544276_103544472 1.09 Gm24870
 predicted gene, 24870
 97552
 0.07
chr6_129526176_129526360 1.04 Gm44120
 predicted gene, 44120
 3706
 0.1
chr11_101669101_101669273 1.03 Arl4d
 ADP-ribosylation factor-like 4D
 3646
 0.12
chr16_32906853_32907017 1.02 Fyttd1
 forty-two-three domain containing 1
 4836
 0.15
chr1_88291560_88291711 1.02 Trpm8
 transient receptor potential cation channel, subfamily M, member 8
 11648
 0.11
chr2_36201411_36201590 0.99 Gm13429
 predicted gene 13429
 814
 0.51
chr13_109881168_109881343 0.98 Pde4d
 phosphodiesterase 4D, cAMP specific
 21847
 0.23
chr7_126260333_126260533 0.93 Sbk1
 SH3-binding kinase 1
 11571
 0.11
chr2_28401752_28401907 0.89 Ppp1r26
 protein phosphatase 1, regulatory subunit 26
 44971
 0.1
chr19_31530752_31530903 0.87 Prkg1
 protein kinase, cGMP-dependent, type I
 133543
 0.05
chr18_67649043_67649260 0.87 Psmg2
 proteasome (prosome, macropain) assembly chaperone 2
 7543
 0.16
chr8_26984786_26984951 0.87 Gm45371
 predicted gene 45371
 4867
 0.11
chr1_184276149_184276321 0.87 Gm37223
 predicted gene, 37223
 82094
 0.09
chr2_137165742_137165931 0.85 Gm28214
 predicted gene 28214
 33147
 0.2
chr14_74794292_74794475 0.85 Lrch1
 leucine-rich repeats and calponin homology (CH) domain containing 1
 608
 0.79
chr6_119405432_119405608 0.83 Adipor2
 adiponectin receptor 2
 11955
 0.2
chr3_136671194_136671345 0.81 Ppp3ca
 protein phosphatase 3, catalytic subunit, alpha isoform
 499
 0.84
chr2_179292139_179292587 0.79 Gm14293
 predicted gene 14293
 51873
 0.14
chr10_66631116_66631267 0.77 Gm28139
 predicted gene 28139
 9727
 0.22
chr16_32427729_32427880 0.77 Pcyt1a
 phosphate cytidylyltransferase 1, choline, alpha isoform
 3117
 0.15
chr6_143530873_143531067 0.74 4930579D09Rik
 RIKEN cDNA 4930579D09 gene
 4538
 0.3
chr4_108362669_108362965 0.74 Shisal2a
 shisa like 2A
 20532
 0.11
chr8_3402101_3402252 0.73 Arhgef18
 rho/rac guanine nucleotide exchange factor (GEF) 18
 9103
 0.17
chr8_23255218_23255374 0.73 Gm45412
 predicted gene 45412
 1339
 0.29
chr11_22636888_22637044 0.72 Gm12053
 predicted gene 12053
 10302
 0.19
chr13_55613448_55613599 0.72 Gm15911
 predicted gene 15911
 8740
 0.1
chr1_71938584_71938854 0.71 Gm28818
 predicted gene 28818
 21594
 0.17
chr2_120518757_120518908 0.71 Zfp106
 zinc finger protein 106
 1714
 0.3
chr2_159732589_159732753 0.71 Gm11445
 predicted gene 11445
 45536
 0.19
chr9_33067630_33067799 0.71 Gm27166
 predicted gene 27166
 35923
 0.17
chr6_98920465_98920616 0.67 Foxp1
 forkhead box P1
 9245
 0.27
chr17_73845744_73845921 0.67 Gm4948
 predicted gene 4948
 25518
 0.16
chr17_5012388_5012845 0.66 Arid1b
 AT rich interactive domain 1B (SWI-like)
 16187
 0.23
chr13_110455904_110456069 0.66 Plk2
 polo like kinase 2
 58189
 0.14
chr10_84803969_84804150 0.65 Gm24226
 predicted gene, 24226
 7124
 0.23
chr13_113163450_113163622 0.65 Gm49564
 predicted gene, 49564
 12086
 0.12
chr1_184605964_184606231 0.65 Rpl21-ps1
 ribosomal protein 21, pseudogene 1
 11151
 0.15
chr2_146099387_146099651 0.64 Cfap61
 cilia and flagella associated protein 61
 52268
 0.15
chr17_8983661_8983825 0.64 1700010I14Rik
 RIKEN cDNA 1700010I14 gene
 4590
 0.27
chr6_34640326_34640484 0.62 Gm13861
 predicted gene 13861
 13489
 0.18
chr4_123633972_123634145 0.62 Gm12926
 predicted gene 12926
 3763
 0.18
chr5_45534505_45534782 0.62 Fam184b
 family with sequence similarity 184, member B
 1899
 0.22
chr14_40830166_40830336 0.61 Sh2d4b
 SH2 domain containing 4B
 23054
 0.21
chr3_54358525_54358723 0.61 Postn
 periostin, osteoblast specific factor
 2485
 0.4
chr17_47628875_47629038 0.60 Usp49
 ubiquitin specific peptidase 49
 1734
 0.19
chr3_85819269_85819420 0.59 Fam160a1
 family with sequence similarity 160, member A1
 2053
 0.31
chr18_62224841_62225012 0.59 Gm9949
 predicted gene 9949
 44800
 0.14
chr7_112270651_112270950 0.58 Mical2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 499
 0.87
chr3_79559741_79559912 0.57 Gm3513
 predicted gene 3513
 7633
 0.12
chr7_45509194_45509417 0.56 Nucb1
 nucleobindin 1
 1010
 0.23
chr11_103102697_103103091 0.56 Acbd4
 acyl-Coenzyme A binding domain containing 4
 127
 0.92
chr13_34242299_34242490 0.56 Slc22a23
 solute carrier family 22, member 23
 48863
 0.11
chr11_55406169_55406386 0.56 Sparc
 secreted acidic cysteine rich glycoprotein
 4112
 0.19
chr6_134043668_134043819 0.55 Etv6
 ets variant 6
 7774
 0.2
chr14_46017259_46017572 0.54 Gm6580
 predicted gene 6580
 10013
 0.17
chr16_77392160_77392548 0.54 Gm21816
 predicted gene, 21816
 7676
 0.13
chr16_91565059_91565210 0.54 Ifngr2
 interferon gamma receptor 2
 3811
 0.13
chr3_104531244_104531395 0.54 Lrig2
 leucine-rich repeats and immunoglobulin-like domains 2
 19401
 0.12
chr11_49247308_49247488 0.54 Mgat1
 mannoside acetylglucosaminyltransferase 1
 79
 0.95
chr5_74660839_74660990 0.53 Lnx1
 ligand of numb-protein X 1
 16715
 0.17
chr8_36031619_36031770 0.53 Rps12-ps24
 ribosomal protein S12, pseudogene 24
 5941
 0.22
chr4_120599080_120599244 0.52 Gm8439
 predicted gene 8439
 10416
 0.14
chr18_38310613_38310764 0.52 Rnf14
 ring finger protein 14
 10936
 0.1
chr8_123097696_123097880 0.52 Spg7
 SPG7, paraplegin matrix AAA peptidase subunit
 3267
 0.11
chr2_26409405_26409631 0.51 Inpp5e
 inositol polyphosphate-5-phosphatase E
 315
 0.75
chr5_140852570_140852762 0.51 Gna12
 guanine nucleotide binding protein, alpha 12
 22235
 0.18
chr7_37208227_37208420 0.51 Gm28075
 predicted gene 28075
 67782
 0.1
chr6_84623037_84623198 0.51 Cyp26b1
 cytochrome P450, family 26, subfamily b, polypeptide 1
 29209
 0.22
chr2_26477777_26477967 0.51 Notch1
 notch 1
 7374
 0.1
chr1_39015594_39015753 0.50 Pdcl3
 phosducin-like 3
 20513
 0.15
chr3_148810176_148810327 0.50 Adgrl2
 adhesion G protein-coupled receptor L2
 12728
 0.29
chr6_58968401_58968557 0.50 BB365896
 expressed sequence BB365896
 2824
 0.19
chr18_31771523_31771682 0.50 Ammecr1l
 AMME chromosomal region gene 1-like
 9798
 0.13
chr6_94231502_94231666 0.50 Magi1
 membrane associated guanylate kinase, WW and PDZ domain containing 1
 51441
 0.15
chr9_69687494_69687666 0.49 B230323A14Rik
 RIKEN cDNA B230323A14 gene
 71160
 0.09
chr7_19818513_19818676 0.49 Gm16174
 predicted gene 16174
 2041
 0.13
chr7_140767632_140767811 0.49 Cyp2e1
 cytochrome P450, family 2, subfamily e, polypeptide 1
 3240
 0.12
chr3_75910357_75910514 0.49 Golim4
 golgi integral membrane protein 4
 7989
 0.22
chr3_127809212_127809380 0.48 Ap1ar
 adaptor-related protein complex 1 associated regulatory protein
 432
 0.73
chr5_64802893_64803289 0.48 Klf3
 Kruppel-like factor 3 (basic)
 297
 0.69
chr5_67260097_67260248 0.48 Tmem33
 transmembrane protein 33
 393
 0.75
chr19_41838995_41839153 0.48 Frat2
 frequently rearranged in advanced T cell lymphomas 2
 9058
 0.14
chr11_112821671_112821851 0.48 4933434M16Rik
 RIKEN cDNA 4933434M16 gene
 3393
 0.25
chr1_170815750_170815913 0.48 Gm25235
 predicted gene, 25235
 17040
 0.13
chr5_129974844_129975008 0.47 Vkorc1l1
 vitamin K epoxide reductase complex, subunit 1-like 1
 2068
 0.19
chr4_135870496_135870942 0.47 Pnrc2
 proline-rich nuclear receptor coactivator 2
 2342
 0.17
chr16_22698076_22698372 0.47 Gm8118
 predicted gene 8118
 12030
 0.18
chr11_83852736_83852913 0.47 Hnf1b
 HNF1 homeobox B
 136
 0.94
chr2_70474959_70475123 0.46 Sp5
 trans-acting transcription factor 5
 118
 0.95
chr1_15610696_15611021 0.46 Gm37138
 predicted gene, 37138
 54609
 0.13
chr7_28957205_28957624 0.45 Actn4
 actinin alpha 4
 4809
 0.11
chr12_76578699_76578851 0.45 Sptb
 spectrin beta, erythrocytic
 5311
 0.17
chrX_73097052_73097231 0.45 Xlr3a
 X-linked lymphocyte-regulated 3A
 46
 0.49
chr8_106138930_106139081 0.45 1810019D21Rik
 RIKEN cDNA 1810019D21 gene
 1940
 0.19
chr9_116091537_116091709 0.45 Gm9385
 predicted pseudogene 9385
 50559
 0.13
chr15_82670462_82670884 0.44 Cyp2d36-ps
 cytochrome P450, family 2, subfamily d, polypeptide 36, pseudogene
 12584
 0.08
chr3_101922485_101922654 0.44 Slc22a15
 solute carrier family 22 (organic anion/cation transporter), member 15
 1810
 0.41
chr8_126734848_126735025 0.44 Gm45805
 predicted gene 45805
 23398
 0.22
chr2_181257756_181258013 0.44 Gmeb2
 glucocorticoid modulatory element binding protein 2
 1753
 0.2
chr5_45110945_45111100 0.44 D5Ertd615e
 DNA segment, Chr 5, ERATO Doi 615, expressed
 58542
 0.13
chr3_107943742_107943913 0.44 Gstm6
 glutathione S-transferase, mu 6
 78
 0.92
chr6_129113449_129113636 0.44 Klrb1-ps1
 killer cell lectin-like receptor subfamily B member 1, pseudogene 1
 2976
 0.16
chr4_60066252_60066431 0.44 Mup7
 major urinary protein 7
 4070
 0.21
chr7_26023934_26024181 0.44 Cyp2b27-ps
 cytochrome P450, family 2, subfamily b, polypeptide 27, pseudogene
 4849
 0.14
chr2_103870054_103870389 0.44 Gm13876
 predicted gene 13876
 18103
 0.09
chr2_72306157_72306335 0.43 Map3k20
 mitogen-activated protein kinase kinase kinase 20
 8345
 0.2
chr7_26143665_26143899 0.43 Cyp2b26-ps
 cytochrome P450, family 2, subfamily b, polypeptide 26, pseudogene
 4810
 0.17
chr1_121301989_121302163 0.43 Gm38283
 predicted gene, 38283
 1245
 0.42
chr11_69781883_69782061 0.43 Zbtb4
 zinc finger and BTB domain containing 4
 6566
 0.06
chr1_170485088_170485365 0.42 Nos1ap
 nitric oxide synthase 1 (neuronal) adaptor protein
 30312
 0.19
chr17_57344446_57344660 0.42 Adgre1
 adhesion G protein-coupled receptor E1
 14138
 0.17
chr17_68312521_68312883 0.42 L3mbtl4
 L3MBTL4 histone methyl-lysine binding protein
 38905
 0.18
chr4_53082761_53082912 0.42 Abca1
 ATP-binding cassette, sub-family A (ABC1), member 1
 41910
 0.13
chr10_42278852_42279003 0.42 Foxo3
 forkhead box O3
 2172
 0.38
chr7_72345699_72346292 0.42 Mctp2
 multiple C2 domains, transmembrane 2
 39387
 0.21
chr2_102197430_102197592 0.41 Ldlrad3
 low density lipoprotein receptor class A domain containing 3
 11126
 0.18
chr4_149062510_149062918 0.41 Gm9506
 predicted gene 9506
 33669
 0.11
chr11_16882054_16882234 0.41 Egfr
 epidermal growth factor receptor
 3994
 0.24
chr10_122455472_122455951 0.41 Gm48878
 predicted gene, 48878
 1579
 0.39
chr2_3356420_3356581 0.41 Gm37525
 predicted gene, 37525
 2496
 0.19
chr13_31894655_31894821 0.41 Gm11380
 predicted gene 11380
 10513
 0.21
chr1_24614263_24614420 0.41 Gm10925
 predicted gene 10925
 310
 0.44
chr7_127009850_127010117 0.41 Mvp
 major vault protein
 1882
 0.11
chr3_133765600_133766533 0.40 Gm6135
 prediticted gene 6135
 25438
 0.2
chr4_139875950_139876108 0.40 Gm1667
 predicted gene 1667
 34459
 0.13
chr3_27859393_27859548 0.40 Gm26040
 predicted gene, 26040
 8643
 0.24
chr4_60737134_60737406 0.40 Mup12
 major urinary protein 12
 4056
 0.21
chr4_136143189_136143532 0.40 Id3
 inhibitor of DNA binding 3
 137
 0.94
chr11_69716247_69716398 0.40 Gm12307
 predicted gene 12307
 14262
 0.05
chr10_86161840_86162013 0.40 Gm15990
 predicted gene 15990
 36099
 0.14
chr13_52150386_52150766 0.40 Gm48199
 predicted gene, 48199
 29835
 0.18
chr4_60497810_60497972 0.40 Mup1
 major urinary protein 1
 1441
 0.3
chr3_150365886_150366049 0.39 Gm6439
 predicted gene 6439
 150114
 0.05
chr6_116650512_116650679 0.39 Depp1
 DEPP1 autophagy regulator
 14
 0.95
chr10_27133710_27134037 0.39 Lama2
 laminin, alpha 2
 77228
 0.1
chr1_160040201_160040352 0.39 Gm37294
 predicted gene, 37294
 4055
 0.19
chr6_5517592_5517751 0.39 Pdk4
 pyruvate dehydrogenase kinase, isoenzyme 4
 21362
 0.26
chr6_12448993_12449152 0.39 Thsd7a
 thrombospondin, type I, domain containing 7A
 29711
 0.24
chr4_61777961_61778274 0.38 Mup19
 major urinary protein 19
 4107
 0.15
chr6_52479304_52479475 0.38 1700094M24Rik
 RIKEN cDNA 1700094M24 gene
 13062
 0.16
chr9_121677227_121677378 0.38 Vipr1
 vasoactive intestinal peptide receptor 1
 8589
 0.11
chr9_69442354_69442630 0.38 Gm18587
 predicted gene, 18587
 2471
 0.17
chr5_88796583_88796899 0.38 Gm42912
 predicted gene 42912
 2845
 0.21
chr10_80130534_80130701 0.38 Stk11
 serine/threonine kinase 11
 3935
 0.1
chr5_123203458_123203883 0.38 Gm43409
 predicted gene 43409
 12082
 0.1
chr13_70831157_70831325 0.38 Gm36529
 predicted gene, 36529
 9210
 0.2
chr19_12457466_12457644 0.38 Mpeg1
 macrophage expressed gene 1
 3224
 0.15
chr15_57889538_57889699 0.37 Derl1
 Der1-like domain family, member 1
 776
 0.67
chr3_104610491_104610642 0.37 Gm26091
 predicted gene, 26091
 9327
 0.11
chrX_36864362_36864513 0.37 C330007P06Rik
 RIKEN cDNA C330007P06 gene
 191
 0.91
chr7_49025943_49026104 0.37 Gm45207
 predicted gene 45207
 36558
 0.14
chr19_5688905_5689088 0.37 Map3k11
 mitogen-activated protein kinase kinase kinase 11
 41
 0.53
chr11_86954758_86954966 0.37 Ypel2
 yippee like 2
 17162
 0.18
chr2_84650666_84651104 0.37 Ctnnd1
 catenin (cadherin associated protein), delta 1
 120
 0.92
chr10_122384642_122385270 0.37 Gm36041
 predicted gene, 36041
 1936
 0.39
chr16_91736910_91737079 0.36 Itsn1
 intersectin 1 (SH3 domain protein 1A)
 6760
 0.15
chr9_72988766_72988933 0.36 Ccpg1
 cell cycle progression 1
 3230
 0.1
chr1_60178803_60178972 0.36 Nbeal1
 neurobeachin like 1
 1712
 0.36
chr2_169634592_169634925 0.36 Tshz2
 teashirt zinc finger family member 2
 1082
 0.55
chr8_76985045_76985216 0.36 Nr3c2
 nuclear receptor subfamily 3, group C, member 2
 76858
 0.1
chr8_82940163_82940321 0.35 Gm18212
 predicted gene, 18212
 12270
 0.24
chr3_60532827_60533127 0.35 Gm37589
 predicted gene, 37589
 2774
 0.28
chr2_104684894_104685441 0.35 Tcp11l1
 t-complex 11 like 1
 901
 0.52
chr15_74785868_74786026 0.35 Gm17189
 predicted gene 17189
 1882
 0.15
chr1_93567830_93567992 0.35 Gm37250
 predicted gene, 37250
 36096
 0.11
chr8_10439826_10440109 0.35 Myo16
 myosin XVI
 167395
 0.03
chr1_186182710_186182892 0.35 Gm37272
 predicted gene, 37272
 544
 0.77
chr11_50290912_50291474 0.34 Maml1
 mastermind like transcriptional coactivator 1
 611
 0.62
chr14_68447677_68447874 0.34 Gm31227
 predicted gene, 31227
 13856
 0.25
chr11_53763211_53763413 0.34 Mir7671
 microRNA 7671
 342
 0.78
chr2_163007366_163007517 0.34 Sgk2
 serum/glucocorticoid regulated kinase 2
 9329
 0.12
chr2_91763068_91763259 0.34 Ambra1
 autophagy/beclin 1 regulator 1
 3282
 0.21
chr10_95942046_95942222 0.34 Eea1
 early endosome antigen 1
 1377
 0.41
chrX_12081574_12081758 0.34 Bcor
 BCL6 interacting corepressor
 1113
 0.62
chr15_38661135_38661289 0.34 Atp6v1c1
 ATPase, H+ transporting, lysosomal V1 subunit C1
 721
 0.55
chr4_61299711_61299917 0.34 Mup14
 major urinary protein 14
 3551
 0.24
chr6_121992123_121992633 0.34 Mug2
 murinoglobulin 2
 14383
 0.19
chr13_90092035_90092214 0.34 Tmem167
 transmembrane protein 167
 2362
 0.24
chr11_79753212_79753391 0.34 Mir365-2
 microRNA 365-2
 26901
 0.12
chr8_35144585_35144741 0.33 Gm45626
 predicted gene 45626
 5783
 0.16
chr4_123718182_123718341 0.33 Ndufs5
 NADH:ubiquinone oxidoreductase core subunit S5
 59
 0.96
chr2_50625194_50625394 0.33 Gm13484
 predicted gene 13484
 32773
 0.19
chr4_60135275_60135767 0.33 Mup2
 major urinary protein 2
 4336
 0.2
chrX_164978971_164979139 0.33 Mospd2
 motile sperm domain containing 2
 1242
 0.39
chr6_94065091_94065371 0.33 Magi1
 membrane associated guanylate kinase, WW and PDZ domain containing 1
 151541
 0.04
chr4_45523336_45523508 0.33 Shb
 src homology 2 domain-containing transforming protein B
 6908
 0.16
chr3_143339999_143340399 0.33 Gm43613
 predicted gene 43613
 9779
 0.21
chr13_98595452_98595618 0.33 Gm4815
 predicted gene 4815
 17966
 0.12
chr1_43066043_43066369 0.32 Tgfbrap1
 transforming growth factor, beta receptor associated protein 1
 5273
 0.14
chr11_113725569_113725747 0.32 Cdc42ep4
 CDC42 effector protein (Rho GTPase binding) 4
 13664
 0.13
chr16_45608261_45608423 0.32 Gcsam
 germinal center associated, signaling and motility
 2038
 0.27
chr15_89477372_89477550 0.32 Arsa
 arylsulfatase A
 36
 0.77
chr3_38115997_38116148 0.32 Rpl21-ps10
 ribosomal protein L21, pseudogene 10
 8150
 0.2
chr19_34863787_34864179 0.32 Pank1
 pantothenate kinase 1
 13866
 0.15
chr1_145972338_145972489 0.32 Gm5263
 predicted gene 5263
 448023
 0.01
chr4_129000922_129001084 0.32 Ak2
 adenylate kinase 2
 7650
 0.16
chr15_10834414_10834584 0.32 Gm19276
 predicted gene, 19276
 19672
 0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxc9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.4 GO:0003162 atrioventricular node development(GO:0003162)
0.2 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.4 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.5 GO:0035564 regulation of kidney size(GO:0035564)
0.1 0.7 GO:0014744 positive regulation of muscle adaptation(GO:0014744)
0.1 0.3 GO:0010912 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.1 0.3 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.2 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.1 0.3 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.1 0.3 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.1 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.1 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.2 GO:1904970 brush border assembly(GO:1904970)
0.0 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.2 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.5 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.5 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.2 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.2 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.0 0.2 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.1 GO:0071316 cellular response to nicotine(GO:0071316)
0.0 0.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.0 0.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.0 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.1 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.4 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.0 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0070640 vitamin D3 metabolic process(GO:0070640)
0.0 0.1 GO:0002838 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.0 0.1 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:2000169 regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0 0.0 GO:0015819 lysine transport(GO:0015819)
0.0 0.0 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.0 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.0 0.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.1 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0 0.0 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.0 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.0 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.0 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0 0.0 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.0 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.0 0.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.0 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.0 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.1 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.0 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.0 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.0 0.1 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.0 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.0 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0032986 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0 0.0 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.0 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.0 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.0 0.3 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.0 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0 0.0 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.0 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.0 GO:0060948 cardiac vascular smooth muscle cell development(GO:0060948)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.0 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0050812 regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.0 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.0 GO:0048296 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.4 GO:0005915 zonula adherens(GO:0005915)
0.1 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0030313 cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.0 GO:0043511 inhibin complex(GO:0043511)
0.0 0.0 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.0 GO:0005775 vacuolar lumen(GO:0005775)
0.0 0.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.0 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.4 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.6 GO:0018656 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.1 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.4 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 0.2 GO:0031711 bradykinin receptor binding(GO:0031711)
0.1 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.0 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.1 GO:0035671 enone reductase activity(GO:0035671)
0.0 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.0 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.0 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.3 GO:0004119 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.0 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.0 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.0 0.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0016443 bidentate ribonuclease III activity(GO:0016443)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.0 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.0 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.0 REACTOME S PHASE Genes involved in S Phase
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.0 REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION Genes involved in Platelet activation, signaling and aggregation
0.0 0.0 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation