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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Hoxd10

Z-value: 0.64

Motif logo

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Transcription factors associated with Hoxd10

Gene Symbol Gene ID Gene Info
ENSMUSG00000050368.3 Hoxd10

Activity of the Hoxd10 motif across conditions

Conditions sorted by the z-value of the Hoxd10 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_40191993_40192245 0.38 Gm5827
predicted gene 5827
1081
0.44
chr3_5425056_5425268 0.27 4930555M17Rik
RIKEN cDNA 4930555M17 gene
90171
0.09
chr13_112282869_112283044 0.25 Ankrd55
ankyrin repeat domain 55
5495
0.19
chr19_29520832_29521011 0.23 A930007I19Rik
RIKEN cDNA A930007I19 gene
49
0.96
chr1_162891657_162891835 0.23 Fmo2
flavin containing monooxygenase 2
5231
0.19
chr17_64763760_64763987 0.23 Dreh
down-regulated in hepatocellular carcinoma
3238
0.25
chr4_109317104_109317295 0.23 Eps15
epidermal growth factor receptor pathway substrate 15
8048
0.21
chr7_97414019_97414355 0.23 Thrsp
thyroid hormone responsive
3332
0.16
chr1_155035905_155036069 0.22 Gm29441
predicted gene 29441
4248
0.21
chr14_68455613_68455772 0.21 Gm31227
predicted gene, 31227
5939
0.27
chr11_16832225_16832426 0.20 Egfros
epidermal growth factor receptor, opposite strand
1623
0.42
chr5_125479434_125479671 0.20 Gm27551
predicted gene, 27551
175
0.92
chr11_16839257_16839592 0.20 Egfros
epidermal growth factor receptor, opposite strand
8722
0.22
chr6_66996154_66996403 0.18 Gm36816
predicted gene, 36816
12135
0.12
chr19_40174636_40174787 0.17 Cyp2c70
cytochrome P450, family 2, subfamily c, polypeptide 70
12575
0.15
chr8_76152377_76152560 0.17 Gm45742
predicted gene 45742
35441
0.19
chr11_16764973_16765411 0.17 Egfr
epidermal growth factor receptor
12962
0.2
chr9_74791015_74791321 0.17 Gm22315
predicted gene, 22315
9098
0.19
chr2_31519719_31520357 0.17 Ass1
argininosuccinate synthetase 1
1548
0.36
chr2_177902871_177903175 0.17 Gm14327
predicted gene 14327
1262
0.38
chr13_16575026_16575177 0.17 Gm48497
predicted gene, 48497
41280
0.17
chr8_40895225_40895376 0.17 Slc7a2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
3138
0.22
chr2_72753133_72753284 0.17 6430710C18Rik
RIKEN cDNA 6430710C18 gene
2355
0.34
chr2_18066311_18066462 0.17 Mllt10
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
1545
0.26
chr10_24258031_24258221 0.17 Moxd1
monooxygenase, DBH-like 1
34581
0.16
chr2_58773392_58773555 0.17 Upp2
uridine phosphorylase 2
8148
0.21
chr5_89466890_89467069 0.16 Gc
vitamin D binding protein
9081
0.22
chr4_76963069_76963220 0.16 Gm23159
predicted gene, 23159
4646
0.28
chr9_74876222_74876428 0.16 Onecut1
one cut domain, family member 1
9841
0.15
chr4_62704468_62704619 0.16 Gm11210
predicted gene 11210
1438
0.36
chr2_72210584_72210735 0.16 Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
11860
0.17
chr2_177471886_177472177 0.16 Zfp970
zinc finger protein 970
7185
0.16
chr1_128080862_128081018 0.16 Gm37625
predicted gene, 37625
8391
0.12
chr12_32693085_32693261 0.16 Gm18726
predicted gene, 18726
16988
0.2
chr12_79501822_79502159 0.16 Rad51b
RAD51 paralog B
174637
0.03
chr2_117026913_117027140 0.15 Gm13981
predicted gene 13981
28540
0.17
chr4_141926137_141926288 0.15 Fhad1
forkhead-associated (FHA) phosphopeptide binding domain 1
3786
0.16
chr3_67267572_67267743 0.15 Mlf1
myeloid leukemia factor 1
106440
0.06
chr5_86938648_86938802 0.15 Gm24121
predicted gene, 24121
9717
0.09
chr13_19395072_19395660 0.15 Gm42683
predicted gene 42683
87
0.82
chr10_31956696_31956848 0.15 Gm18189
predicted gene, 18189
16897
0.27
chr15_81249111_81249532 0.15 8430426J06Rik
RIKEN cDNA 8430426J06 gene
1353
0.36
chr9_74894770_74895613 0.15 Onecut1
one cut domain, family member 1
28707
0.13
chr13_109823681_109823902 0.15 Pde4d
phosphodiesterase 4D, cAMP specific
66570
0.13
chr13_90464205_90464390 0.15 Gm47520
predicted gene, 47520
46197
0.16
chr3_101578122_101578273 0.15 Atp1a1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
637
0.68
chr11_16783062_16783213 0.15 Egfr
epidermal growth factor receptor
30907
0.16
chr9_106273797_106274092 0.14 Poc1a
POC1 centriolar protein A
7117
0.12
chr11_28684227_28684558 0.14 2810471M01Rik
RIKEN cDNA 2810471M01 gene
2828
0.27
chr11_16890762_16890930 0.14 Egfr
epidermal growth factor receptor
12696
0.19
chr3_114294859_114295010 0.14 Col11a1
collagen, type XI, alpha 1
129656
0.06
chr19_44396602_44396753 0.14 Scd1
stearoyl-Coenzyme A desaturase 1
10013
0.14
chr6_57647294_57647456 0.14 Gm19244
predicted gene, 19244
30098
0.11
chr11_17651863_17652036 0.14 Gm12016
predicted gene 12016
12766
0.3
chr5_92607049_92607221 0.14 Stbd1
starch binding domain 1
4067
0.19
chr6_119883269_119883450 0.13 Gm15532
predicted gene 15532
9561
0.15
chr1_162964214_162964365 0.13 Gm37273
predicted gene, 37273
18725
0.14
chr12_16562529_16562714 0.13 Lpin1
lipin 1
177
0.97
chr13_24359125_24359350 0.13 Gm11342
predicted gene 11342
16713
0.12
chr11_16779122_16779339 0.13 Egfr
epidermal growth factor receptor
27000
0.17
chr11_16761103_16761540 0.13 Egfr
epidermal growth factor receptor
9091
0.2
chr2_134495277_134495573 0.13 Hao1
hydroxyacid oxidase 1, liver
58882
0.16
chr6_112635828_112636003 0.13 Gm5578
predicted pseudogene 5578
30371
0.14
chr5_151018980_151019139 0.13 Gm8675
predicted gene 8675
9758
0.23
chr5_90550918_90551069 0.13 Gm2602
predicted gene 2602
7856
0.13
chr13_24358292_24358443 0.12 Gm11342
predicted gene 11342
17583
0.12
chr11_69098275_69098686 0.12 Per1
period circadian clock 1
468
0.58
chr9_94016628_94017010 0.12 Gm5369
predicted gene 5369
122643
0.06
chr3_60515813_60516054 0.12 Mbnl1
muscleblind like splicing factor 1
12195
0.22
chr6_113144373_113144524 0.12 Setd5
SET domain containing 5
15767
0.14
chr5_104436788_104436985 0.12 Spp1
secreted phosphoprotein 1
694
0.6
chr1_127898839_127898990 0.12 Rab3gap1
RAB3 GTPase activating protein subunit 1
1999
0.31
chr11_16831950_16832169 0.12 Egfros
epidermal growth factor receptor, opposite strand
1357
0.48
chr6_91752974_91753164 0.12 Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
2885
0.21
chr17_81175582_81175959 0.12 Gm50042
predicted gene, 50042
70968
0.11
chr11_11831601_11831799 0.12 Ddc
dopa decarboxylase
4580
0.21
chr8_40650786_40650937 0.12 Mtmr7
myotubularin related protein 7
16064
0.14
chr13_28877494_28877645 0.12 2610307P16Rik
RIKEN cDNA 2610307P16 gene
5887
0.2
chr11_94216406_94216835 0.12 Tob1
transducer of ErbB-2.1
5166
0.19
chr3_107256063_107256233 0.11 Prok1
prokineticin 1
16441
0.12
chr8_36283239_36283399 0.11 Lonrf1
LON peptidase N-terminal domain and ring finger 1
33803
0.16
chr13_44819256_44819472 0.11 Gm22213
predicted gene, 22213
18919
0.2
chr2_71874267_71874418 0.11 Pdk1
pyruvate dehydrogenase kinase, isoenzyme 1
599
0.75
chr1_67169746_67169962 0.11 Cps1
carbamoyl-phosphate synthetase 1
46828
0.14
chr8_60947880_60948031 0.11 Clcn3
chloride channel, voltage-sensitive 3
6793
0.17
chr12_103996630_103996801 0.11 Gm28577
predicted gene 28577
136
0.92
chr11_16892807_16893180 0.11 Egfr
epidermal growth factor receptor
12192
0.19
chr7_140723099_140723551 0.11 Olfr542-ps1
olfactory receptor 542, pseudogene 1
2043
0.18
chr15_56280670_56280835 0.11 Hba-ps3
hemoglobin alpha, pseudogene 3
108363
0.07
chr19_21625734_21625885 0.11 1110059E24Rik
RIKEN cDNA 1110059E24 gene
4959
0.24
chr11_16814706_16815122 0.11 Egfros
epidermal growth factor receptor, opposite strand
15788
0.21
chr6_71999696_71999905 0.11 Gm26628
predicted gene, 26628
36025
0.1
chr13_9057691_9057882 0.11 Gm36264
predicted gene, 36264
18665
0.13
chr5_99251194_99251660 0.11 Rasgef1b
RasGEF domain family, member 1B
1500
0.46
chr15_59048966_59049301 0.11 Mtss1
MTSS I-BAR domain containing 1
6331
0.24
chr8_76147063_76147228 0.11 Gm45742
predicted gene 45742
30118
0.21
chr5_66149579_66149965 0.11 Rbm47
RNA binding motif protein 47
1184
0.28
chr19_26823384_26823535 0.11 4931403E22Rik
RIKEN cDNA 4931403E22 gene
448
0.84
chr3_118487666_118487837 0.11 Gm26871
predicted gene, 26871
30092
0.12
chr11_16901525_16901732 0.11 Egfr
epidermal growth factor receptor
3557
0.24
chr14_116350280_116350464 0.11 Gm38045
predicted gene, 38045
399843
0.01
chr4_76368191_76368359 0.11 Ptprd
protein tyrosine phosphatase, receptor type, D
24032
0.21
chr15_85747646_85747958 0.11 Ppara
peroxisome proliferator activated receptor alpha
11671
0.14
chr5_92503161_92503312 0.11 Scarb2
scavenger receptor class B, member 2
2401
0.25
chr9_31589555_31589723 0.11 Gm18226
predicted gene, 18226
21393
0.16
chr17_64759833_64759998 0.11 Gm17133
predicted gene 17133
5819
0.21
chr14_67053186_67053337 0.11 Ppp2r2a
protein phosphatase 2, regulatory subunit B, alpha
9732
0.17
chr4_130716973_130717173 0.11 Snord85
small nucleolar RNA, C/D box 85
32561
0.11
chr9_116389320_116389471 0.11 D730003K21Rik
RIKEN cDNA D730003K21 gene
58227
0.15
chr4_108060521_108060686 0.11 Scp2
sterol carrier protein 2, liver
10760
0.13
chr11_120560210_120560367 0.11 P4hb
prolyl 4-hydroxylase, beta polypeptide
948
0.26
chrX_57836208_57836359 0.10 Gm14631
predicted gene 14631
82415
0.08
chr7_114203967_114204169 0.10 Gm45454
predicted gene 45454
5020
0.23
chr17_35808048_35808407 0.10 Ier3
immediate early response 3
13457
0.07
chr11_58167864_58168078 0.10 Gemin5
gem nuclear organelle associated protein 5
568
0.6
chr19_10103951_10104278 0.10 Fads2
fatty acid desaturase 2
2368
0.23
chr3_116271828_116272000 0.10 Gpr88
G-protein coupled receptor 88
18411
0.18
chr15_97187929_97188091 0.10 Gm32885
predicted gene, 32885
20766
0.21
chr17_64644992_64645205 0.10 Man2a1
mannosidase 2, alpha 1
44362
0.16
chr7_99193825_99193976 0.10 Gm45012
predicted gene 45012
8466
0.13
chr19_10087853_10088030 0.10 Fads2
fatty acid desaturase 2
775
0.57
chr19_60532004_60532219 0.10 Cacul1
CDK2 associated, cullin domain 1
5438
0.23
chr19_40155227_40155577 0.10 Cyp2c70
cytochrome P450, family 2, subfamily c, polypeptide 70
31884
0.13
chr1_24116155_24116306 0.10 Gm26607
predicted gene, 26607
9045
0.17
chr18_90541359_90541533 0.10 Tmx3
thioredoxin-related transmembrane protein 3
4392
0.18
chr6_24262961_24263227 0.10 Slc13a1
solute carrier family 13 (sodium/sulfate symporters), member 1
95002
0.08
chr18_33377697_33377885 0.10 Gm5503
predicted gene 5503
7164
0.27
chr6_114877506_114877696 0.10 Vgll4
vestigial like family member 4
2494
0.3
chr7_68976071_68976222 0.10 Gm44691
predicted gene 44691
13258
0.21
chr3_58235650_58235811 0.10 Gm26166
predicted gene, 26166
54627
0.11
chr6_114888678_114888863 0.10 Vgll4
vestigial like family member 4
13663
0.2
chr3_52011173_52011324 0.10 Gm37465
predicted gene, 37465
7223
0.13
chr5_45903098_45903253 0.10 4930405L22Rik
RIKEN cDNA 4930405L22 gene
29234
0.16
chr2_69724507_69724673 0.10 Ppig
peptidyl-prolyl isomerase G (cyclophilin G)
1264
0.33
chr13_115162784_115162981 0.10 Gm18759
predicted gene, 18759
1938
0.33
chr11_118265609_118265912 0.10 Usp36
ubiquitin specific peptidase 36
288
0.89
chr11_63891944_63892129 0.10 Hs3st3b1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
30254
0.17
chr6_103697460_103697614 0.10 Chl1
cell adhesion molecule L1-like
213
0.95
chr6_15930296_15930597 0.10 Gm43990
predicted gene, 43990
94357
0.08
chr4_121163852_121164031 0.10 Rlf
rearranged L-myc fusion sequence
24593
0.11
chr6_56907100_56907281 0.10 Gm3793
predicted gene 3793
608
0.64
chr10_68056586_68056943 0.10 Rtkn2
rhotekin 2
12796
0.2
chr3_60099135_60099299 0.10 Sucnr1
succinate receptor 1
17315
0.18
chr16_93367939_93368144 0.10 1810044K17Rik
RIKEN cDNA 1810044K17 gene
198
0.89
chr13_24359929_24360183 0.10 Gm11342
predicted gene 11342
15894
0.12
chr2_129197178_129197487 0.09 Gm4430
predicted gene 4430
206
0.85
chr17_71561749_71561923 0.09 Spdya
speedy/RINGO cell cycle regulator family, member A
5578
0.12
chr3_129593850_129594054 0.09 Elovl6
ELOVL family member 6, elongation of long chain fatty acids (yeast)
41572
0.12
chr3_94710144_94710297 0.09 Selenbp2
selenium binding protein 2
16561
0.1
chr6_108606639_108606790 0.09 0610040F04Rik
RIKEN cDNA 0610040F04 gene
7281
0.16
chr1_67144557_67144947 0.09 Cps1
carbamoyl-phosphate synthetase 1
21726
0.21
chr6_56904208_56904367 0.09 Gm3793
predicted gene 3793
2295
0.19
chr10_53318105_53318261 0.09 Gm17823
predicted gene, 17823
18041
0.12
chr15_59430248_59430452 0.09 Nsmce2
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
56063
0.12
chr9_74318679_74318830 0.09 Gm24141
predicted gene, 24141
43856
0.14
chr8_93168995_93169226 0.09 Ces1d
carboxylesterase 1D
865
0.51
chr1_67153015_67153221 0.09 Cps1
carbamoyl-phosphate synthetase 1
30092
0.19
chr2_72223568_72223719 0.09 Rapgef4os2
Rap guanine nucleotide exchange factor (GEF) 4, opposite strand 2
8659
0.17
chr4_44920931_44921086 0.09 Zcchc7
zinc finger, CCHC domain containing 7
2110
0.25
chr2_12899690_12899932 0.09 Pter
phosphotriesterase related
24230
0.21
chr11_84290556_84290741 0.09 Acaca
acetyl-Coenzyme A carboxylase alpha
10193
0.25
chr10_87541080_87541552 0.09 Pah
phenylalanine hydroxylase
5357
0.23
chr13_25015682_25015833 0.09 Mrs2
MRS2 magnesium transporter
4019
0.19
chr16_42910828_42911152 0.09 Gm19522
predicted gene, 19522
1075
0.5
chr1_153739671_153739993 0.09 Rgs16
regulator of G-protein signaling 16
517
0.61
chr16_56598260_56598451 0.09 Tfg
Trk-fused gene
107339
0.06
chr6_144086911_144087062 0.09 Sox5os1
SRY (sex determining region Y)-box 5, opposite strand 1
65078
0.13
chr2_28119005_28119156 0.09 F730016J06Rik
RIKEN cDNA F730016J06 gene
873
0.59
chr10_80437858_80438035 0.09 Tcf3
transcription factor 3
4299
0.1
chr4_134837509_134837670 0.09 Maco1
macoilin 1
15560
0.17
chr15_7195034_7195185 0.09 Egflam
EGF-like, fibronectin type III and laminin G domains
27960
0.21
chr17_69982645_69982841 0.09 Dlgap1
DLG associated protein 1
13322
0.24
chr2_126622639_126622795 0.09 Hdc
histidine decarboxylase
3418
0.2
chr5_8422645_8423469 0.09 Slc25a40
solute carrier family 25, member 40
158
0.72
chr7_113961088_113961254 0.09 Gm45615
predicted gene 45615
125727
0.05
chr10_95255137_95255325 0.09 Gm48880
predicted gene, 48880
59622
0.08
chr2_27769095_27769412 0.09 Rxra
retinoid X receptor alpha
29052
0.21
chr10_57301198_57301349 0.09 Gm7001
predicted gene 7001
10384
0.21
chr18_56396921_56397088 0.09 Gramd3
GRAM domain containing 3
3333
0.25
chr2_90583663_90583816 0.09 Ptprj
protein tyrosine phosphatase, receptor type, J
3092
0.29
chr14_16572962_16573173 0.09 Rarb
retinoic acid receptor, beta
1978
0.34
chr6_50561677_50561828 0.09 Cycs
cytochrome c, somatic
4197
0.12
chr5_45437140_45437291 0.09 Gm42413
predicted gene, 42413
2826
0.18
chr15_55042916_55043114 0.09 Taf2
TATA-box binding protein associated factor 2
3151
0.21
chr14_45385956_45386177 0.09 Gnpnat1
glucosamine-phosphate N-acetyltransferase 1
582
0.65
chr2_6328324_6328528 0.09 AL845275.1
novel protein
5346
0.2
chr10_40511959_40512217 0.09 Gm18671
predicted gene, 18671
36804
0.14
chr3_141299865_141300028 0.09 Pdha2
pyruvate dehydrogenase E1 alpha 2
87591
0.1
chr11_16882054_16882234 0.09 Egfr
epidermal growth factor receptor
3994
0.24
chr19_57258284_57258443 0.09 4930449E18Rik
RIKEN cDNA 4930449E18 gene
15597
0.18
chr4_134847461_134847666 0.09 Maco1
macoilin 1
5586
0.19
chr6_39781272_39781654 0.09 Mrps33
mitochondrial ribosomal protein S33
24579
0.15
chr3_98407172_98407364 0.09 Zfp697
zinc finger protein 697
24720
0.13
chr12_30348373_30348544 0.09 Sntg2
syntrophin, gamma 2
9225
0.26
chr17_46448212_46448499 0.09 Gm5093
predicted gene 5093
8258
0.1
chr1_67201067_67201218 0.09 Gm15668
predicted gene 15668
48058
0.14
chr10_89512416_89512679 0.09 Nr1h4
nuclear receptor subfamily 1, group H, member 4
5889
0.23
chr13_58389633_58389784 0.09 Mir7-1
microRNA 7-1
3178
0.14
chr8_128726356_128726507 0.09 Itgb1
integrin beta 1 (fibronectin receptor beta)
2098
0.32
chr12_29082462_29082658 0.09 4833405L11Rik
RIKEN cDNA 4833405L11 gene
24177
0.19

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Hoxd10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.2 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.0 0.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:1903416 response to glycoside(GO:1903416)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.2 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.0 0.1 GO:0072338 creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.1 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.1 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.0 0.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.0 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0030647 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.1 GO:0045908 negative regulation of vasodilation(GO:0045908)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.0 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.0 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.0 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0006559 L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.1 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.0 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.0 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.0 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.0 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.0 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.0 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.0 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0 0.0 GO:2000359 regulation of binding of sperm to zona pellucida(GO:2000359)
0.0 0.1 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.0 0.0 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.0 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.0 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.0 0.0 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.0 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.0 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.0 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.1 GO:0045714 low-density lipoprotein particle receptor biosynthetic process(GO:0045713) regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0 0.0 GO:0009826 unidimensional cell growth(GO:0009826)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.0 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.2 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.0 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.0 GO:2001069 glycogen binding(GO:2001069)
0.0 0.0 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.0 GO:0016215 acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling