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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Insm1

Z-value: 1.54

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Transcription factors associated with Insm1

Gene Symbol Gene ID Gene Info
Insm1
ENSMUSG00000068154.4 insulinoma-associated 1

Activity of the Insm1 motif across conditions

Conditions sorted by the z-value of the Insm1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr9_63555594_63556179 9.72 Gm16759
 predicted gene, 16759
 24534
 0.17
chr11_95232020_95232325 1.59 Gm11515
 predicted gene 11515
 6540
 0.15
chr2_31485846_31486386 1.56 Ass1
 argininosuccinate synthetase 1
 11656
 0.18
chr19_8412638_8412828 1.16 Slc22a30
 solute carrier family 22, member 30
 7622
 0.21
chr19_8139481_8139632 1.09 Slc22a28
 solute carrier family 22, member 28
 7574
 0.21
chr1_184101076_184101417 0.79 Dusp10
 dual specificity phosphatase 10
 66865
 0.11
chr18_59175547_59176237 0.71 Chsy3
 chondroitin sulfate synthase 3
 242
 0.96
chr7_109566693_109566893 0.70 Denn2b
 DENN domain containing 2B
 26360
 0.12
chr17_34024149_34024494 0.70 Ring1
 ring finger protein 1
 331
 0.42
chr15_39800082_39800233 0.67 Gm16291
 predicted gene 16291
 3112
 0.26
chr13_57675035_57675197 0.65 Spock1
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
 232471
 0.02
chr4_141148421_141148589 0.64 Fbxo42
 F-box protein 42
 583
 0.63
chr11_98962485_98962641 0.63 Rara
 retinoic acid receptor, alpha
 2151
 0.18
chr15_79328216_79328601 0.61 Pla2g6
 phospholipase A2, group VI
 18
 0.96
chr16_59600745_59600902 0.60 Crybg3
 beta-gamma crystallin domain containing 3
 156
 0.96
chr16_4866490_4866641 0.59 4930562C15Rik
 RIKEN cDNA 4930562C15 gene
 2242
 0.21
chr5_125074638_125074861 0.58 Gm42839
 predicted gene 42839
 12092
 0.16
chr4_135745411_135745562 0.57 Gm12988
 predicted gene 12988
 11209
 0.12
chr9_86721274_86721452 0.57 Gm37484
 predicted gene, 37484
 9359
 0.11
chr12_29082462_29082658 0.56 4833405L11Rik
 RIKEN cDNA 4833405L11 gene
 24177
 0.19
chr14_19808226_19808383 0.55 Nid2
 nidogen 2
 3068
 0.21
chr15_59040831_59041076 0.55 Mtss1
 MTSS I-BAR domain containing 1
 356
 0.89
chr3_152763675_152763826 0.55 Pigk
 phosphatidylinositol glycan anchor biosynthesis, class K
 369
 0.88
chr7_63899068_63899509 0.54 Gm27252
 predicted gene 27252
 1314
 0.37
chr8_107311781_107311960 0.53 Nfat5
 nuclear factor of activated T cells 5
 18311
 0.18
chr14_27298745_27298912 0.52 Arhgef3
 Rho guanine nucleotide exchange factor (GEF) 3
 37238
 0.15
chr13_51089168_51089510 0.52 Spin1
 spindlin 1
 11541
 0.24
chr2_58773576_58773851 0.52 Upp2
 uridine phosphorylase 2
 8388
 0.21
chr15_38299804_38299955 0.51 Klf10
 Kruppel-like factor 10
 84
 0.96
chr11_100568089_100568249 0.51 Cnp
 2',3'-cyclic nucleotide 3' phosphodiesterase
 6735
 0.1
chr3_18186474_18186625 0.50 Gm23686
 predicted gene, 23686
 8924
 0.24
chr3_142948874_142949040 0.50 Gm2574
 predicted pseudogene 2574
 13654
 0.17
chr16_37685226_37685393 0.50 Gm4600
 predicted gene 4600
 12031
 0.18
chr15_79333263_79333463 0.50 Pla2g6
 phospholipase A2, group VI
 4973
 0.12
chr7_98423598_98423760 0.49 Gm44507
 predicted gene 44507
 8055
 0.13
chr5_125495068_125495293 0.49 Aacs
 acetoacetyl-CoA synthetase
 10969
 0.13
chr17_46052256_46052407 0.47 Vegfa
 vascular endothelial growth factor A
 19962
 0.13
chr9_44083438_44083791 0.47 Usp2
 ubiquitin specific peptidase 2
 1325
 0.2
chr3_96172047_96172606 0.46 Sf3b4
 splicing factor 3b, subunit 4
 6
 0.54
chr10_79684018_79684169 0.46 Cdc34
 cell division cycle 34
 294
 0.76
chr17_68285429_68285617 0.45 L3mbtl4
 L3MBTL4 histone methyl-lysine binding protein
 11726
 0.26
chr6_47396063_47396225 0.45 Gm18584
 predicted gene, 18584
 36945
 0.16
chr17_34972548_34972711 0.44 Hspa1l
 heat shock protein 1-like
 74
 0.8
chr5_125516996_125517147 0.44 Aacs
 acetoacetyl-CoA synthetase
 1828
 0.29
chr10_127188743_127188894 0.44 Arhgef25
 Rho guanine nucleotide exchange factor (GEF) 25
 46
 0.94
chr6_31261904_31262196 0.44 2210408F21Rik
 RIKEN cDNA 2210408F21 gene
 15798
 0.16
chr2_31508672_31508887 0.44 Ass1
 argininosuccinate synthetase 1
 8053
 0.18
chr12_104338853_104339031 0.43 Serpina3k
 serine (or cysteine) peptidase inhibitor, clade A, member 3K
 456
 0.43
chr15_31253435_31253717 0.43 Dap
 death-associated protein
 14760
 0.15
chr19_3623839_3624006 0.43 Lrp5
 low density lipoprotein receptor-related protein 5
 8130
 0.16
chr6_90492906_90493086 0.42 Aldh1l1
 aldehyde dehydrogenase 1 family, member L1
 6569
 0.11
chr13_58208598_58208750 0.42 Ubqln1
 ubiquilin 1
 6945
 0.11
chr7_123378143_123378338 0.41 Lcmt1
 leucine carboxyl methyltransferase 1
 184
 0.94
chr1_66816824_66817235 0.41 Kansl1l
 KAT8 regulatory NSL complex subunit 1-like
 517
 0.58
chr8_19784863_19785335 0.41 Gm10060
 predicted gene 10060
 353
 0.89
chr3_81039705_81039904 0.40 Gm16000
 predicted gene 16000
 633
 0.66
chr2_154558857_154559033 0.40 Necab3
 N-terminal EF-hand calcium binding protein 3
 55
 0.95
chr6_146339917_146340100 0.40 Gm44087
 predicted gene, 44087
 36409
 0.16
chr17_83069993_83070341 0.40 Gm29052
 predicted gene 29052
 1262
 0.48
chr11_69547199_69547367 0.39 Dnah2
 dynein, axonemal, heavy chain 2
 1825
 0.17
chr3_138286503_138286658 0.39 Adh1
 alcohol dehydrogenase 1 (class I)
 8929
 0.12
chr14_25488854_25489267 0.39 Gm47921
 predicted gene, 47921
 9006
 0.14
chr11_3535686_3535900 0.39 Gm11947
 predicted gene 11947
 1555
 0.2
chr2_164359753_164359904 0.39 Slpi
 secretory leukocyte peptidase inhibitor
 3321
 0.13
chr4_126467726_126468262 0.39 Ago1
 argonaute RISC catalytic subunit 1
 427
 0.74
chr3_52257597_52258053 0.38 Foxo1
 forkhead box O1
 10511
 0.12
chrX_140458132_140458283 0.38 Prps1
 phosphoribosyl pyrophosphate synthetase 1
 1594
 0.39
chr6_24527214_24527411 0.37 Ndufa5
 NADH:ubiquinone oxidoreductase subunit A5
 214
 0.85
chr12_45037426_45037748 0.37 Stxbp6
 syntaxin binding protein 6 (amisyn)
 24623
 0.19
chr9_65968905_65969060 0.37 Csnk1g1
 casein kinase 1, gamma 1
 10566
 0.16
chr17_25397945_25398101 0.37 Cacna1h
 calcium channel, voltage-dependent, T type, alpha 1H subunit
 8551
 0.1
chr6_70709789_70709957 0.37 Gm30211
 predicted gene, 30211
 9201
 0.13
chr7_97788226_97788577 0.37 Pak1
 p21 (RAC1) activated kinase 1
 140
 0.96
chr8_20122500_20122829 0.37 Gm21769
 predicted gene, 21769
 280
 0.92
chr16_90934526_90934702 0.37 Cfap298
 cilia and flagella associate protien 298
 108
 0.77
chr6_66859498_66859662 0.37 Gm9794
 predicted pseudogene 9794
 16163
 0.13
chr12_98628007_98628201 0.36 Spata7
 spermatogenesis associated 7
 53
 0.96
chr11_4186980_4187537 0.36 Tbc1d10a
 TBC1 domain family, member 10a
 436
 0.69
chr2_167324607_167324945 0.36 B4galt5
 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
 10876
 0.18
chr5_33253374_33253525 0.36 Gm43850
 predicted gene 43850
 1869
 0.27
chr8_20297005_20297289 0.35 6820431F20Rik
 RIKEN cDNA 6820431F20 gene
 285
 0.93
chr8_93183570_93183871 0.35 Gm45909
 predicted gene 45909
 7638
 0.14
chr19_4493105_4493260 0.35 2010003K11Rik
 RIKEN cDNA 2010003K11 gene
 5401
 0.13
chr11_43927096_43927431 0.35 Adra1b
 adrenergic receptor, alpha 1b
 26053
 0.2
chrX_9272438_9272819 0.35 Xk
 X-linked Kx blood group
 128
 0.94
chr11_113127851_113128293 0.35 2610035D17Rik
 RIKEN cDNA 2610035D17 gene
 45005
 0.18
chr1_177796375_177796892 0.35 Adss
 adenylosuccinate synthetase, non muscle
 122
 0.96
chr2_60269617_60269768 0.34 Rpl10a-ps4
 ribosomal protein L10A, pseudogene 4
 5882
 0.17
chr14_20185433_20185783 0.34 Kcnk5
 potassium channel, subfamily K, member 5
 3799
 0.16
chr6_17306389_17306751 0.34 Cav1
 caveolin 1, caveolae protein
 147
 0.96
chr11_103697219_103697553 0.34 Gosr2
 golgi SNAP receptor complex member 2
 308
 0.5
chr9_55253735_55254087 0.34 Nrg4
 neuregulin 4
 11450
 0.18
chr16_20097870_20098456 0.33 Klhl24
 kelch-like 24
 571
 0.77
chr19_46328692_46329074 0.33 Fbxl15
 F-box and leucine-rich repeat protein 15
 696
 0.41
chr11_78422437_78422874 0.32 Slc13a2
 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
 438
 0.69
chr8_85519627_85519778 0.32 Gpt2
 glutamic pyruvate transaminase (alanine aminotransferase) 2
 293
 0.89
chr9_106888487_106888638 0.32 Rbm15b
 RNA binding motif protein 15B
 1134
 0.3
chr8_40903804_40903955 0.32 Slc7a2
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
 5441
 0.18
chr6_129528344_129528723 0.32 Gabarapl1
 gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
 4627
 0.09
chr7_28597835_28598003 0.32 Pak4
 p21 (RAC1) activated kinase 4
 167
 0.56
chr15_76294294_76294662 0.32 Smpd5
 sphingomyelin phosphodiesterase 5
 130
 0.88
chr3_130681571_130681744 0.32 Ostc
 oligosaccharyltransferase complex subunit (non-catalytic)
 14965
 0.13
chr5_147748468_147748664 0.32 Gm43156
 predicted gene 43156
 3050
 0.26
chr15_59007009_59007401 0.31 4930544F09Rik
 RIKEN cDNA 4930544F09 gene
 23069
 0.16
chr17_46131074_46131225 0.31 Rsph9
 radial spoke head 9 homolog (Chlamydomonas)
 5646
 0.11
chr5_32034405_32034556 0.31 Babam2
 BRISC and BRCA1 A complex member 2
 11498
 0.19
chr11_117821867_117822183 0.31 Tk1
 thymidine kinase 1
 3792
 0.09
chr2_163288924_163289099 0.31 Tox2
 TOX high mobility group box family member 2
 31367
 0.16
chr1_51741438_51741641 0.31 Gm28055
 predicted gene 28055
 5404
 0.23
chr10_125354052_125354243 0.31 Slc16a7
 solute carrier family 16 (monocarboxylic acid transporters), member 7
 11968
 0.22
chr10_127167327_127167512 0.30 B4galnt1
 beta-1,4-N-acetyl-galactosaminyl transferase 1
 1560
 0.19
chr15_59002495_59002896 0.30 4930544F09Rik
 RIKEN cDNA 4930544F09 gene
 18559
 0.16
chr3_51159499_51159691 0.30 Gm38246
 predicted gene, 38246
 55935
 0.09
chr2_34775525_34776380 0.30 Hspa5
 heat shock protein 5
 1105
 0.4
chr10_123693502_123693679 0.30 Gm19169
 predicted gene, 19169
 110002
 0.07
chr5_120475950_120476223 0.29 Sds
 serine dehydratase
 440
 0.7
chr3_52617818_52618183 0.29 Gm10293
 predicted pseudogene 10293
 5165
 0.27
chr4_123748931_123749287 0.29 Akirin1
 akirin 1
 1122
 0.42
chr12_103907475_103907626 0.29 Serpina1c
 serine (or cysteine) peptidase inhibitor, clade A, member 1C
 2663
 0.15
chr14_73776184_73776350 0.29 Gm24540
 predicted gene, 24540
 8299
 0.18
chr18_76119534_76119864 0.29 2900057B20Rik
 RIKEN cDNA 2900057B20 gene
 21228
 0.19
chr9_83834067_83834712 0.29 Ttk
 Ttk protein kinase
 300
 0.91
chr2_31504934_31505459 0.29 Ass1
 argininosuccinate synthetase 1
 4470
 0.21
chr3_32396117_32396611 0.28 Pik3ca
 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
 1307
 0.41
chr14_66103708_66103859 0.28 Ephx2
 epoxide hydrolase 2, cytoplasmic
 6877
 0.17
chr12_85339310_85339673 0.28 Nek9
 NIMA (never in mitosis gene a)-related expressed kinase 9
 129
 0.93
chr13_119488836_119489180 0.28 Tmem267
 transmembrane protein 267
 148
 0.85
chr7_44256470_44256632 0.28 Acp4
 acid phosphatase 4
 654
 0.31
chr16_33684835_33685093 0.28 Heg1
 heart development protein with EGF-like domains 1
 419
 0.88
chr1_130715772_130716198 0.28 Pfkfb2
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
 171
 0.49
chr4_9616122_9616273 0.27 Asph
 aspartate-beta-hydroxylase
 20508
 0.22
chr18_62025539_62025690 0.27 Sh3tc2
 SH3 domain and tetratricopeptide repeats 2
 47655
 0.14
chr3_36532798_36533054 0.27 Gm11549
 predicted gene 11549
 542
 0.65
chr3_97226229_97226380 0.27 Bcl9
 B cell CLL/lymphoma 9
 1060
 0.5
chr4_3939020_3939731 0.27 Chchd7
 coiled-coil-helix-coiled-coil-helix domain containing 7
 47
 0.94
chr2_4717227_4717378 0.27 Bend7
 BEN domain containing 7
 529
 0.79
chr19_57363088_57363331 0.27 Fam160b1
 family with sequence similarity 160, member B1
 2179
 0.23
chr11_115178601_115178800 0.26 Nat9
 N-acetyltransferase 9 (GCN5-related, putative)
 8381
 0.11
chr17_84935947_84936728 0.26 Ppm1b
 protein phosphatase 1B, magnesium dependent, beta isoform
 20404
 0.15
chr9_74874885_74875056 0.26 Onecut1
 one cut domain, family member 1
 8486
 0.16
chr2_165337323_165337478 0.26 Elmo2
 engulfment and cell motility 2
 10921
 0.14
chr9_43738133_43738287 0.26 Gm30015
 predicted gene, 30015
 1255
 0.34
chr8_84712053_84712451 0.26 Nfix
 nuclear factor I/X
 1816
 0.2
chr2_151494417_151494783 0.26 Nsfl1c
 NSFL1 (p97) cofactor (p47)
 289
 0.84
chr15_77823733_77823908 0.26 Myh9
 myosin, heavy polypeptide 9, non-muscle
 10589
 0.14
chr6_139852911_139853089 0.26 Pik3c2g
 phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
 9352
 0.21
chr2_167696514_167696665 0.26 A530013C23Rik
 RIKEN cDNA A530013C23 gene
 5408
 0.12
chr7_12927207_12927358 0.26 Rnf225
 ring finger protein 225
 134
 0.9
chr2_11778396_11778580 0.26 Ankrd16
 ankyrin repeat domain 16
 3
 0.95
chr17_34859046_34859197 0.26 Cfb
 complement factor B
 80
 0.87
chr2_58741116_58741490 0.26 Gm13559
 predicted gene 13559
 664
 0.72
chr8_122716674_122716851 0.26 Cbfa2t3
 CBFA2/RUNX1 translocation partner 3
 17653
 0.09
chrX_99975701_99975883 0.25 Eda
 ectodysplasin-A
 11
 0.99
chr2_104815840_104816064 0.25 Qser1
 glutamine and serine rich 1
 744
 0.58
chr9_15306463_15306690 0.25 4931406C07Rik
 RIKEN cDNA 4931406C07 gene
 128
 0.61
chr1_59670971_59671144 0.25 Sumo1
 small ubiquitin-like modifier 1
 223
 0.86
chr2_31509568_31509756 0.25 Ass1
 argininosuccinate synthetase 1
 8828
 0.18
chr19_46707203_46707544 0.25 As3mt
 arsenic (+3 oxidation state) methyltransferase
 85
 0.96
chr8_95146444_95146776 0.25 Kifc3
 kinesin family member C3
 4063
 0.14
chr4_10459968_10460323 0.25 Gm11814
 predicted gene 11814
 20402
 0.22
chr15_8131587_8131766 0.25 Nup155
 nucleoporin 155
 1578
 0.41
chr17_15376604_15376755 0.25 Dll1
 delta like canonical Notch ligand 1
 193
 0.93
chr4_62697341_62697495 0.25 Rgs3
 regulator of G-protein signaling 3
 2048
 0.28
chr17_5755888_5756129 0.25 3300005D01Rik
 RIKEN cDNA 3300005D01 gene
 42649
 0.13
chr10_44701947_44702137 0.25 Gm47388
 predicted gene, 47388
 4862
 0.13
chr10_75411570_75411753 0.25 Upb1
 ureidopropionase, beta
 1618
 0.35
chr8_22878603_22878765 0.25 Gm45555
 predicted gene 45555
 5095
 0.18
chrX_140540637_140540856 0.24 Tsc22d3
 TSC22 domain family, member 3
 1922
 0.35
chr19_7240751_7240928 0.24 Naa40
 N(alpha)-acetyltransferase 40, NatD catalytic subunit
 195
 0.89
chr14_30913507_30913826 0.24 Itih3
 inter-alpha trypsin inhibitor, heavy chain 3
 463
 0.7
chr4_24574389_24574545 0.24 Mms22l
 MMS22-like, DNA repair protein
 4381
 0.32
chr5_102571751_102571934 0.24 1700013M08Rik
 RIKEN cDNA 1700013M08 gene
 88553
 0.09
chr7_99837512_99837672 0.24 Neu3
 neuraminidase 3
 9175
 0.12
chr4_125122748_125123219 0.24 Zc3h12a
 zinc finger CCCH type containing 12A
 463
 0.76
chr17_25839280_25839490 0.24 Rhot2
 ras homolog family member T2
 1214
 0.15
chr9_77744429_77744594 0.24 Gclc
 glutamate-cysteine ligase, catalytic subunit
 10024
 0.13
chr9_63414369_63414559 0.24 Gm16759
 predicted gene, 16759
 15083
 0.14
chrX_142489982_142490297 0.24 Gm25915
 predicted gene, 25915
 4692
 0.21
chr6_129233700_129233907 0.23 2310001H17Rik
 RIKEN cDNA 2310001H17 gene
 171
 0.92
chr14_21143556_21143728 0.23 Adk
 adenosine kinase
 67490
 0.11
chr14_73162192_73162413 0.23 Rcbtb2
 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
 362
 0.86
chr10_75475274_75475445 0.23 Gm48158
 predicted gene, 48158
 8033
 0.13
chr11_77884094_77884410 0.23 Pipox
 pipecolic acid oxidase
 292
 0.87
chr1_182817032_182817419 0.23 Susd4
 sushi domain containing 4
 52330
 0.12
chr5_138187143_138187299 0.23 Taf6
 TATA-box binding protein associated factor 6
 0
 0.75
chr3_89912250_89912528 0.23 Gm42809
 predicted gene 42809
 527
 0.51
chr4_149426608_149426780 0.23 Ube4b
 ubiquitination factor E4B
 55
 0.96
chr10_87920604_87920755 0.22 Tyms-ps
 thymidylate synthase, pseudogene
 46168
 0.12
chr14_34317951_34318429 0.22 Glud1
 glutamate dehydrogenase 1
 7463
 0.1
chr16_92301405_92301603 0.22 Smim11
 small integral membrane protein 11
 208
 0.9
chr18_38600801_38601184 0.22 Spry4
 sprouty RTK signaling antagonist 4
 423
 0.54
chr10_84440530_84440894 0.22 Gm47962
 predicted gene, 47962
 114
 0.49
chr2_128412432_128412601 0.22 Morrbid
 myeloid RNA regulator of BCL2L11 induced cell death
 9551
 0.18
chr19_5490661_5490908 0.22 Cfl1
 cofilin 1, non-muscle
 219
 0.76
chr3_27690451_27690616 0.22 Fndc3b
 fibronectin type III domain containing 3B
 19865
 0.25
chr1_131828122_131828273 0.22 Slc41a1
 solute carrier family 41, member 1
 220
 0.91
chr10_87873898_87874083 0.22 Igf1os
 insulin-like growth factor 1, opposite strand
 10609
 0.2
chr7_45131841_45131992 0.22 Flt3l
 FMS-like tyrosine kinase 3 ligand
 159
 0.78
chr16_55844021_55844404 0.22 Nfkbiz
 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
 5313
 0.18
chr17_78735372_78735770 0.22 Strn
 striatin, calmodulin binding protein
 1625
 0.31

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Insm1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.2 0.6 GO:0010046 response to mycotoxin(GO:0010046)
0.2 0.5 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1 0.6 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.4 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 0.4 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.4 GO:0042851 L-alanine metabolic process(GO:0042851)
0.1 0.4 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
0.1 0.5 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.3 GO:0001757 somite specification(GO:0001757)
0.1 0.5 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.3 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.3 GO:0071672 negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.2 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.4 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.4 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.2 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.2 GO:1902075 cellular response to salt(GO:1902075)
0.1 0.2 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.0 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.1 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.0 0.1 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.4 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0071727 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.1 GO:0015819 lysine transport(GO:0015819)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742)
0.0 0.3 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.2 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.2 GO:0001842 neural fold formation(GO:0001842)
0.0 0.2 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.1 GO:0048320 axial mesoderm formation(GO:0048320)
0.0 0.1 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.3 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.1 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.0 0.3 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0003099 positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.1 GO:0034756 regulation of iron ion transport(GO:0034756)
0.0 0.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.4 GO:0042026 protein refolding(GO:0042026)
0.0 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0036166 phenotypic switching(GO:0036166)
0.0 0.0 GO:0097460 ferrous iron import into cell(GO:0097460)
0.0 0.6 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:0032819 positive regulation of natural killer cell proliferation(GO:0032819)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.2 GO:0046051 UTP metabolic process(GO:0046051)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.1 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.0 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.0 GO:0060948 cardiac vascular smooth muscle cell development(GO:0060948)
0.0 0.1 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.1 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.0 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.0 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.0 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.0 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.0 0.0 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.0 GO:0015888 thiamine transport(GO:0015888)
0.0 0.1 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.0 GO:0002432 granuloma formation(GO:0002432)
0.0 0.0 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.0 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.0 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.0 GO:0046104 thymidine metabolic process(GO:0046104)
0.0 0.0 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0 0.1 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.0 0.2 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.0 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0032960 regulation of inositol trisphosphate biosynthetic process(GO:0032960)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.0 GO:1900368 regulation of RNA interference(GO:1900368)
0.0 0.1 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.0 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.0 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.0 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.0 0.2 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.0 GO:1903660 complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.0 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.0 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.0 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.0 0.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.0 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.0 GO:1901525 regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.1 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.0 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.0 GO:0045047 protein targeting to ER(GO:0045047)
0.0 0.1 GO:0071038 nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038)
0.0 0.0 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.0 GO:0060112 generation of ovulation cycle rhythm(GO:0060112)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.6 GO:0070852 cell body fiber(GO:0070852)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.3 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.1 GO:0097651 phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.0 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.2 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.2 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.1 0.4 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0015189 arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.0 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0035276 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) ethanol binding(GO:0035276)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0 0.0 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.0 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.0 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.0 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.3 GO:0052770 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 0.0 GO:0032551 UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.0 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.0 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.2 GO:0031492 nucleosomal DNA binding(GO:0031492)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.0 PID SHP2 PATHWAY SHP2 signaling
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels