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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Insm1

Z-value: 1.54

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Transcription factors associated with Insm1

Gene Symbol	Gene ID	Gene Info
Insm1 Ensembl NCBI MGI UniProt	ENSMUSG00000068154.4	Insm1

Activity of the Insm1 motif across conditions

Conditions sorted by the z-value of the Insm1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_63555594_63556179	9.72	Gm16759	predicted gene, 16759	24534	0.17
chr11_95232020_95232325	1.59	Gm11515	predicted gene 11515	6540	0.15
chr2_31485846_31486386	1.56	Ass1	argininosuccinate synthetase 1	11656	0.18
chr19_8412638_8412828	1.16	Slc22a30	solute carrier family 22, member 30	7622	0.21
chr19_8139481_8139632	1.09	Slc22a28	solute carrier family 22, member 28	7574	0.21
chr1_184101076_184101417	0.79	Dusp10	dual specificity phosphatase 10	66865	0.11
chr18_59175547_59176237	0.71	Chsy3	chondroitin sulfate synthase 3	242	0.96
chr7_109566693_109566893	0.70	Denn2b	DENN domain containing 2B	26360	0.12
chr17_34024149_34024494	0.70	Ring1	ring finger protein 1	331	0.42
chr15_39800082_39800233	0.67	Gm16291	predicted gene 16291	3112	0.26
chr13_57675035_57675197	0.65	Spock1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1	232471	0.02
chr4_141148421_141148589	0.64	Fbxo42	F-box protein 42	583	0.63
chr11_98962485_98962641	0.63	Rara	retinoic acid receptor, alpha	2151	0.18
chr15_79328216_79328601	0.61	Pla2g6	phospholipase A2, group VI	18	0.96
chr16_59600745_59600902	0.60	Crybg3	beta-gamma crystallin domain containing 3	156	0.96
chr16_4866490_4866641	0.59	4930562C15Rik	RIKEN cDNA 4930562C15 gene	2242	0.21
chr5_125074638_125074861	0.58	Gm42839	predicted gene 42839	12092	0.16
chr4_135745411_135745562	0.57	Gm12988	predicted gene 12988	11209	0.12
chr9_86721274_86721452	0.57	Gm37484	predicted gene, 37484	9359	0.11
chr12_29082462_29082658	0.56	4833405L11Rik	RIKEN cDNA 4833405L11 gene	24177	0.19
chr14_19808226_19808383	0.55	Nid2	nidogen 2	3068	0.21
chr15_59040831_59041076	0.55	Mtss1	MTSS I-BAR domain containing 1	356	0.89
chr3_152763675_152763826	0.55	Pigk	phosphatidylinositol glycan anchor biosynthesis, class K	369	0.88
chr7_63899068_63899509	0.54	Gm27252	predicted gene 27252	1314	0.37
chr8_107311781_107311960	0.53	Nfat5	nuclear factor of activated T cells 5	18311	0.18
chr14_27298745_27298912	0.52	Arhgef3	Rho guanine nucleotide exchange factor (GEF) 3	37238	0.15
chr13_51089168_51089510	0.52	Spin1	spindlin 1	11541	0.24
chr2_58773576_58773851	0.52	Upp2	uridine phosphorylase 2	8388	0.21
chr15_38299804_38299955	0.51	Klf10	Kruppel-like factor 10	84	0.96
chr11_100568089_100568249	0.51	Cnp	2',3'-cyclic nucleotide 3' phosphodiesterase	6735	0.1
chr3_18186474_18186625	0.50	Gm23686	predicted gene, 23686	8924	0.24
chr3_142948874_142949040	0.50	Gm2574	predicted pseudogene 2574	13654	0.17
chr16_37685226_37685393	0.50	Gm4600	predicted gene 4600	12031	0.18
chr15_79333263_79333463	0.50	Pla2g6	phospholipase A2, group VI	4973	0.12
chr7_98423598_98423760	0.49	Gm44507	predicted gene 44507	8055	0.13
chr5_125495068_125495293	0.49	Aacs	acetoacetyl-CoA synthetase	10969	0.13
chr17_46052256_46052407	0.47	Vegfa	vascular endothelial growth factor A	19962	0.13
chr9_44083438_44083791	0.47	Usp2	ubiquitin specific peptidase 2	1325	0.2
chr3_96172047_96172606	0.46	Sf3b4	splicing factor 3b, subunit 4	6	0.54
chr10_79684018_79684169	0.46	Cdc34	cell division cycle 34	294	0.76
chr17_68285429_68285617	0.45	L3mbtl4	L3MBTL4 histone methyl-lysine binding protein	11726	0.26
chr6_47396063_47396225	0.45	Gm18584	predicted gene, 18584	36945	0.16
chr17_34972548_34972711	0.44	Hspa1l	heat shock protein 1-like	74	0.8
chr5_125516996_125517147	0.44	Aacs	acetoacetyl-CoA synthetase	1828	0.29
chr10_127188743_127188894	0.44	Arhgef25	Rho guanine nucleotide exchange factor (GEF) 25	46	0.94
chr6_31261904_31262196	0.44	2210408F21Rik	RIKEN cDNA 2210408F21 gene	15798	0.16
chr2_31508672_31508887	0.44	Ass1	argininosuccinate synthetase 1	8053	0.18
chr12_104338853_104339031	0.43	Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	456	0.43
chr15_31253435_31253717	0.43	Dap	death-associated protein	14760	0.15
chr19_3623839_3624006	0.43	Lrp5	low density lipoprotein receptor-related protein 5	8130	0.16
chr6_90492906_90493086	0.42	Aldh1l1	aldehyde dehydrogenase 1 family, member L1	6569	0.11
chr13_58208598_58208750	0.42	Ubqln1	ubiquilin 1	6945	0.11
chr7_123378143_123378338	0.41	Lcmt1	leucine carboxyl methyltransferase 1	184	0.94
chr1_66816824_66817235	0.41	Kansl1l	KAT8 regulatory NSL complex subunit 1-like	517	0.58
chr8_19784863_19785335	0.41	Gm10060	predicted gene 10060	353	0.89
chr3_81039705_81039904	0.40	Gm16000	predicted gene 16000	633	0.66
chr2_154558857_154559033	0.40	Necab3	N-terminal EF-hand calcium binding protein 3	55	0.95
chr6_146339917_146340100	0.40	Gm44087	predicted gene, 44087	36409	0.16
chr17_83069993_83070341	0.40	Gm29052	predicted gene 29052	1262	0.48
chr11_69547199_69547367	0.39	Dnah2	dynein, axonemal, heavy chain 2	1825	0.17
chr3_138286503_138286658	0.39	Adh1	alcohol dehydrogenase 1 (class I)	8929	0.12
chr14_25488854_25489267	0.39	Gm47921	predicted gene, 47921	9006	0.14
chr11_3535686_3535900	0.39	Gm11947	predicted gene 11947	1555	0.2
chr2_164359753_164359904	0.39	Slpi	secretory leukocyte peptidase inhibitor	3321	0.13
chr4_126467726_126468262	0.39	Ago1	argonaute RISC catalytic subunit 1	427	0.74
chr3_52257597_52258053	0.38	Foxo1	forkhead box O1	10511	0.12
chrX_140458132_140458283	0.38	Prps1	phosphoribosyl pyrophosphate synthetase 1	1594	0.39
chr6_24527214_24527411	0.37	Ndufa5	NADH:ubiquinone oxidoreductase subunit A5	214	0.85
chr12_45037426_45037748	0.37	Stxbp6	syntaxin binding protein 6 (amisyn)	24623	0.19
chr9_65968905_65969060	0.37	Csnk1g1	casein kinase 1, gamma 1	10566	0.16
chr17_25397945_25398101	0.37	Cacna1h	calcium channel, voltage-dependent, T type, alpha 1H subunit	8551	0.1
chr6_70709789_70709957	0.37	Gm30211	predicted gene, 30211	9201	0.13
chr7_97788226_97788577	0.37	Pak1	p21 (RAC1) activated kinase 1	140	0.96
chr8_20122500_20122829	0.37	Gm21769	predicted gene, 21769	280	0.92
chr16_90934526_90934702	0.37	Cfap298	cilia and flagella associate protien 298	108	0.77
chr6_66859498_66859662	0.37	Gm9794	predicted pseudogene 9794	16163	0.13
chr12_98628007_98628201	0.36	Spata7	spermatogenesis associated 7	53	0.96
chr11_4186980_4187537	0.36	Tbc1d10a	TBC1 domain family, member 10a	436	0.69
chr2_167324607_167324945	0.36	B4galt5	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5	10876	0.18
chr5_33253374_33253525	0.36	Gm43850	predicted gene 43850	1869	0.27
chr8_20297005_20297289	0.35	6820431F20Rik	RIKEN cDNA 6820431F20 gene	285	0.93
chr8_93183570_93183871	0.35	Gm45909	predicted gene 45909	7638	0.14
chr19_4493105_4493260	0.35	2010003K11Rik	RIKEN cDNA 2010003K11 gene	5401	0.13
chr11_43927096_43927431	0.35	Adra1b	adrenergic receptor, alpha 1b	26053	0.2
chrX_9272438_9272819	0.35	Xk	X-linked Kx blood group	128	0.94
chr11_113127851_113128293	0.35	2610035D17Rik	RIKEN cDNA 2610035D17 gene	45005	0.18
chr1_177796375_177796892	0.35	Adss	adenylosuccinate synthetase, non muscle	122	0.96
chr2_60269617_60269768	0.34	Rpl10a-ps4	ribosomal protein L10A, pseudogene 4	5882	0.17
chr14_20185433_20185783	0.34	Kcnk5	potassium channel, subfamily K, member 5	3799	0.16
chr6_17306389_17306751	0.34	Cav1	caveolin 1, caveolae protein	147	0.96
chr11_103697219_103697553	0.34	Gosr2	golgi SNAP receptor complex member 2	308	0.5
chr9_55253735_55254087	0.34	Nrg4	neuregulin 4	11450	0.18
chr16_20097870_20098456	0.33	Klhl24	kelch-like 24	571	0.77
chr19_46328692_46329074	0.33	Fbxl15	F-box and leucine-rich repeat protein 15	696	0.41
chr11_78422437_78422874	0.32	Slc13a2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	438	0.69
chr8_85519627_85519778	0.32	Gpt2	glutamic pyruvate transaminase (alanine aminotransferase) 2	293	0.89
chr9_106888487_106888638	0.32	Rbm15b	RNA binding motif protein 15B	1134	0.3
chr8_40903804_40903955	0.32	Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	5441	0.18
chr6_129528344_129528723	0.32	Gabarapl1	gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1	4627	0.09
chr7_28597835_28598003	0.32	Pak4	p21 (RAC1) activated kinase 4	167	0.56
chr15_76294294_76294662	0.32	Smpd5	sphingomyelin phosphodiesterase 5	130	0.88
chr3_130681571_130681744	0.32	Ostc	oligosaccharyltransferase complex subunit (non-catalytic)	14965	0.13
chr5_147748468_147748664	0.32	Gm43156	predicted gene 43156	3050	0.26
chr15_59007009_59007401	0.31	4930544F09Rik	RIKEN cDNA 4930544F09 gene	23069	0.16
chr17_46131074_46131225	0.31	Rsph9	radial spoke head 9 homolog (Chlamydomonas)	5646	0.11
chr5_32034405_32034556	0.31	Babam2	BRISC and BRCA1 A complex member 2	11498	0.19
chr11_117821867_117822183	0.31	Tk1	thymidine kinase 1	3792	0.09
chr2_163288924_163289099	0.31	Tox2	TOX high mobility group box family member 2	31367	0.16
chr1_51741438_51741641	0.31	Gm28055	predicted gene 28055	5404	0.23
chr10_125354052_125354243	0.31	Slc16a7	solute carrier family 16 (monocarboxylic acid transporters), member 7	11968	0.22
chr10_127167327_127167512	0.30	B4galnt1	beta-1,4-N-acetyl-galactosaminyl transferase 1	1560	0.19
chr15_59002495_59002896	0.30	4930544F09Rik	RIKEN cDNA 4930544F09 gene	18559	0.16
chr3_51159499_51159691	0.30	Gm38246	predicted gene, 38246	55935	0.09
chr2_34775525_34776380	0.30	Hspa5	heat shock protein 5	1105	0.4
chr10_123693502_123693679	0.30	Gm19169	predicted gene, 19169	110002	0.07
chr5_120475950_120476223	0.29	Sds	serine dehydratase	440	0.7
chr3_52617818_52618183	0.29	Gm10293	predicted pseudogene 10293	5165	0.27
chr4_123748931_123749287	0.29	Akirin1	akirin 1	1122	0.42
chr12_103907475_103907626	0.29	Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	2663	0.15
chr14_73776184_73776350	0.29	Gm24540	predicted gene, 24540	8299	0.18
chr18_76119534_76119864	0.29	2900057B20Rik	RIKEN cDNA 2900057B20 gene	21228	0.19
chr9_83834067_83834712	0.29	Ttk	Ttk protein kinase	300	0.91
chr2_31504934_31505459	0.29	Ass1	argininosuccinate synthetase 1	4470	0.21
chr3_32396117_32396611	0.28	Pik3ca	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	1307	0.41
chr14_66103708_66103859	0.28	Ephx2	epoxide hydrolase 2, cytoplasmic	6877	0.17
chr12_85339310_85339673	0.28	Nek9	NIMA (never in mitosis gene a)-related expressed kinase 9	129	0.93
chr13_119488836_119489180	0.28	Tmem267	transmembrane protein 267	148	0.85
chr7_44256470_44256632	0.28	Acp4	acid phosphatase 4	654	0.31
chr16_33684835_33685093	0.28	Heg1	heart development protein with EGF-like domains 1	419	0.88
chr1_130715772_130716198	0.28	Pfkfb2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	171	0.49
chr4_9616122_9616273	0.27	Asph	aspartate-beta-hydroxylase	20508	0.22
chr18_62025539_62025690	0.27	Sh3tc2	SH3 domain and tetratricopeptide repeats 2	47655	0.14
chr3_36532798_36533054	0.27	Gm11549	predicted gene 11549	542	0.65
chr3_97226229_97226380	0.27	Bcl9	B cell CLL/lymphoma 9	1060	0.5
chr4_3939020_3939731	0.27	Chchd7	coiled-coil-helix-coiled-coil-helix domain containing 7	47	0.94
chr2_4717227_4717378	0.27	Bend7	BEN domain containing 7	529	0.79
chr19_57363088_57363331	0.27	Fam160b1	family with sequence similarity 160, member B1	2179	0.23
chr11_115178601_115178800	0.26	Nat9	N-acetyltransferase 9 (GCN5-related, putative)	8381	0.11
chr17_84935947_84936728	0.26	Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	20404	0.15
chr9_74874885_74875056	0.26	Onecut1	one cut domain, family member 1	8486	0.16
chr2_165337323_165337478	0.26	Elmo2	engulfment and cell motility 2	10921	0.14
chr9_43738133_43738287	0.26	Gm30015	predicted gene, 30015	1255	0.34
chr8_84712053_84712451	0.26	Nfix	nuclear factor I/X	1816	0.2
chr2_151494417_151494783	0.26	Nsfl1c	NSFL1 (p97) cofactor (p47)	289	0.84
chr15_77823733_77823908	0.26	Myh9	myosin, heavy polypeptide 9, non-muscle	10589	0.14
chr6_139852911_139853089	0.26	Pik3c2g	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma	9352	0.21
chr2_167696514_167696665	0.26	A530013C23Rik	RIKEN cDNA A530013C23 gene	5408	0.12
chr7_12927207_12927358	0.26	Rnf225	ring finger protein 225	134	0.9
chr2_11778396_11778580	0.26	Ankrd16	ankyrin repeat domain 16	3	0.95
chr17_34859046_34859197	0.26	Cfb	complement factor B	80	0.87
chr2_58741116_58741490	0.26	Gm13559	predicted gene 13559	664	0.72
chr8_122716674_122716851	0.26	Cbfa2t3	CBFA2/RUNX1 translocation partner 3	17653	0.09
chrX_99975701_99975883	0.25	Eda	ectodysplasin-A	11	0.99
chr2_104815840_104816064	0.25	Qser1	glutamine and serine rich 1	744	0.58
chr9_15306463_15306690	0.25	4931406C07Rik	RIKEN cDNA 4931406C07 gene	128	0.61
chr1_59670971_59671144	0.25	Sumo1	small ubiquitin-like modifier 1	223	0.86
chr2_31509568_31509756	0.25	Ass1	argininosuccinate synthetase 1	8828	0.18
chr19_46707203_46707544	0.25	As3mt	arsenic (+3 oxidation state) methyltransferase	85	0.96
chr8_95146444_95146776	0.25	Kifc3	kinesin family member C3	4063	0.14
chr4_10459968_10460323	0.25	Gm11814	predicted gene 11814	20402	0.22
chr15_8131587_8131766	0.25	Nup155	nucleoporin 155	1578	0.41
chr17_15376604_15376755	0.25	Dll1	delta like canonical Notch ligand 1	193	0.93
chr4_62697341_62697495	0.25	Rgs3	regulator of G-protein signaling 3	2048	0.28
chr17_5755888_5756129	0.25	3300005D01Rik	RIKEN cDNA 3300005D01 gene	42649	0.13
chr10_44701947_44702137	0.25	Gm47388	predicted gene, 47388	4862	0.13
chr10_75411570_75411753	0.25	Upb1	ureidopropionase, beta	1618	0.35
chr8_22878603_22878765	0.25	Gm45555	predicted gene 45555	5095	0.18
chrX_140540637_140540856	0.24	Tsc22d3	TSC22 domain family, member 3	1922	0.35
chr19_7240751_7240928	0.24	Naa40	N(alpha)-acetyltransferase 40, NatD catalytic subunit	195	0.89
chr14_30913507_30913826	0.24	Itih3	inter-alpha trypsin inhibitor, heavy chain 3	463	0.7
chr4_24574389_24574545	0.24	Mms22l	MMS22-like, DNA repair protein	4381	0.32
chr5_102571751_102571934	0.24	1700013M08Rik	RIKEN cDNA 1700013M08 gene	88553	0.09
chr7_99837512_99837672	0.24	Neu3	neuraminidase 3	9175	0.12
chr4_125122748_125123219	0.24	Zc3h12a	zinc finger CCCH type containing 12A	463	0.76
chr17_25839280_25839490	0.24	Rhot2	ras homolog family member T2	1214	0.15
chr9_77744429_77744594	0.24	Gclc	glutamate-cysteine ligase, catalytic subunit	10024	0.13
chr9_63414369_63414559	0.24	Gm16759	predicted gene, 16759	15083	0.14
chrX_142489982_142490297	0.24	Gm25915	predicted gene, 25915	4692	0.21
chr6_129233700_129233907	0.23	2310001H17Rik	RIKEN cDNA 2310001H17 gene	171	0.92
chr14_21143556_21143728	0.23	Adk	adenosine kinase	67490	0.11
chr14_73162192_73162413	0.23	Rcbtb2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	362	0.86
chr10_75475274_75475445	0.23	Gm48158	predicted gene, 48158	8033	0.13
chr11_77884094_77884410	0.23	Pipox	pipecolic acid oxidase	292	0.87
chr1_182817032_182817419	0.23	Susd4	sushi domain containing 4	52330	0.12
chr5_138187143_138187299	0.23	Taf6	TATA-box binding protein associated factor 6	0	0.75
chr3_89912250_89912528	0.23	Gm42809	predicted gene 42809	527	0.51
chr4_149426608_149426780	0.23	Ube4b	ubiquitination factor E4B	55	0.96
chr10_87920604_87920755	0.22	Tyms-ps	thymidylate synthase, pseudogene	46168	0.12
chr14_34317951_34318429	0.22	Glud1	glutamate dehydrogenase 1	7463	0.1
chr16_92301405_92301603	0.22	Smim11	small integral membrane protein 11	208	0.9
chr18_38600801_38601184	0.22	Spry4	sprouty RTK signaling antagonist 4	423	0.54
chr10_84440530_84440894	0.22	Gm47962	predicted gene, 47962	114	0.49
chr2_128412432_128412601	0.22	Morrbid	myeloid RNA regulator of BCL2L11 induced cell death	9551	0.18
chr19_5490661_5490908	0.22	Cfl1	cofilin 1, non-muscle	219	0.76
chr3_27690451_27690616	0.22	Fndc3b	fibronectin type III domain containing 3B	19865	0.25
chr1_131828122_131828273	0.22	Slc41a1	solute carrier family 41, member 1	220	0.91
chr10_87873898_87874083	0.22	Igf1os	insulin-like growth factor 1, opposite strand	10609	0.2
chr7_45131841_45131992	0.22	Flt3l	FMS-like tyrosine kinase 3 ligand	159	0.78
chr16_55844021_55844404	0.22	Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta	5313	0.18
chr17_78735372_78735770	0.22	Strn	striatin, calmodulin binding protein	1625	0.31

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Insm1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.2	0.6	GO:0010046	response to mycotoxin(GO:0010046)
0.2	0.5	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1	0.6	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.4	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1	0.4	GO:0006481	C-terminal protein methylation(GO:0006481)
0.1	0.4	GO:0042851	L-alanine metabolic process(GO:0042851)
0.1	0.4	GO:0061535	glutamate secretion, neurotransmission(GO:0061535)
0.1	0.5	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.1	0.3	GO:0001757	somite specification(GO:0001757)
0.1	0.5	GO:0006167	AMP biosynthetic process(GO:0006167)
0.1	0.5	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.1	0.3	GO:0061153	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1	0.3	GO:0071672	negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.1	0.2	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.1	0.2	GO:0070375	ERK5 cascade(GO:0070375)
0.1	0.4	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.1	0.4	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.1	0.2	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1	0.2	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
0.1	0.2	GO:1902075	cellular response to salt(GO:1902075)
0.1	0.2	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1	0.4	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.1	0.2	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.2	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.2	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.0	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.1	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.1	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0	0.1	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.0	0.1	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.1	GO:0006059	hexitol metabolic process(GO:0006059)
0.0	0.4	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.1	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0	0.1	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.2	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.1	GO:0071727	response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0	0.1	GO:0030070	insulin processing(GO:0030070)
0.0	0.1	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.2	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.0	0.2	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.1	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.1	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.1	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.0	0.1	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	0.1	GO:0015819	lysine transport(GO:0015819)
0.0	0.1	GO:0006742	NADP catabolic process(GO:0006742)
0.0	0.3	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
0.0	0.1	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.2	GO:0035280	miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0	0.1	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.2	GO:0001842	neural fold formation(GO:0001842)
0.0	0.2	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.1	GO:0048320	axial mesoderm formation(GO:0048320)
0.0	0.1	GO:0034241	positive regulation of macrophage fusion(GO:0034241)
0.0	0.1	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.3	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.0	0.1	GO:2000259	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.3	GO:0036315	cellular response to sterol(GO:0036315)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0003099	positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.1	GO:0034756	regulation of iron ion transport(GO:0034756)
0.0	0.1	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.0	0.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.1	GO:0060591	chondroblast differentiation(GO:0060591)
0.0	0.1	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.0	0.1	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0	0.4	GO:0042026	protein refolding(GO:0042026)
0.0	0.7	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.1	GO:0036166	phenotypic switching(GO:0036166)
0.0	0.0	GO:0097460	ferrous iron import into cell(GO:0097460)
0.0	0.6	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.1	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.2	GO:0007288	sperm axoneme assembly(GO:0007288)
0.0	0.1	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.1	GO:0032819	positive regulation of natural killer cell proliferation(GO:0032819)
0.0	0.1	GO:0046878	positive regulation of saliva secretion(GO:0046878)
0.0	0.1	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.0	0.1	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.1	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0	0.2	GO:0046051	UTP metabolic process(GO:0046051)
0.0	0.1	GO:0035964	COPI-coated vesicle budding(GO:0035964)
0.0	0.2	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.1	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.0	0.1	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.1	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.0	0.1	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.1	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.0	0.2	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.0	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.0	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
0.0	0.1	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.0	0.1	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.0	0.1	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.1	GO:0035973	aggrephagy(GO:0035973)
0.0	0.2	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.1	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0	0.1	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.0	GO:0006068	ethanol catabolic process(GO:0006068)
0.0	0.0	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.0	GO:0090241	negative regulation of histone H4 acetylation(GO:0090241)
0.0	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.1	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.0	0.0	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.0	0.3	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.1	GO:1903772	regulation of viral budding via host ESCRT complex(GO:1903772)
0.0	0.0	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
0.0	0.0	GO:0015888	thiamine transport(GO:0015888)
0.0	0.1	GO:0090383	phagosome acidification(GO:0090383)
0.0	0.0	GO:0002432	granuloma formation(GO:0002432)
0.0	0.0	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.1	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.0	0.1	GO:0072015	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0	0.0	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.0	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0	0.0	GO:0046104	thymidine metabolic process(GO:0046104)
0.0	0.0	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.1	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0	0.1	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.1	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.0	0.1	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	0.1	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0032960	regulation of inositol trisphosphate biosynthetic process(GO:0032960)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.0	GO:0090365	regulation of mRNA modification(GO:0090365)
0.0	0.0	GO:1900368	regulation of RNA interference(GO:1900368)
0.0	0.1	GO:0032825	positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.0	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.0	0.1	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.0	GO:0072674	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0	0.0	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.0	GO:0042939	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0	0.0	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.0	GO:1903660	complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.1	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.0	0.0	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0	0.0	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.0	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.1	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.0	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.0	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.0	0.0	GO:1901525	regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.0	0.1	GO:0060294	cilium movement involved in cell motility(GO:0060294)
0.0	0.1	GO:0035814	negative regulation of renal sodium excretion(GO:0035814)
0.0	0.1	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.0	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.0	0.0	GO:0045047	protein targeting to ER(GO:0045047)
0.0	0.1	GO:0071038	nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038)
0.0	0.0	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.0	0.0	GO:0060112	generation of ovulation cycle rhythm(GO:0060112)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.1	0.4	GO:0071141	SMAD protein complex(GO:0071141)
0.1	0.5	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.7	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	0.6	GO:0070852	cell body fiber(GO:0070852)
0.0	0.3	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.0	0.2	GO:0032021	NELF complex(GO:0032021)
0.0	0.2	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.2	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.3	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.3	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0097454	Schwann cell microvillus(GO:0097454)
0.0	0.2	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:1990761	growth cone lamellipodium(GO:1990761)
0.0	0.1	GO:0097651	phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0	0.2	GO:0001650	fibrillar center(GO:0001650)
0.0	0.4	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.2	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.1	GO:0031523	Myb complex(GO:0031523)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0036449	microtubule minus-end(GO:0036449)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.2	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.2	GO:0034464	BBSome(GO:0034464)
0.0	0.1	GO:0097513	myosin II filament(GO:0097513)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0	0.1	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.0	0.2	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.4	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	0.2	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.2	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.5	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.1	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.2	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.0	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.0	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.1	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1	0.6	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.1	0.2	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.1	0.2	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.2	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.1	0.4	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1	0.2	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.3	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.3	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.4	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.0	0.2	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.2	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.5	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
0.0	0.1	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.2	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.2	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.6	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.1	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.1	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.0	0.1	GO:0015189	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0	0.4	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.2	GO:0043426	MRF binding(GO:0043426)
0.0	0.5	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.1	GO:0030619	U1 snRNA binding(GO:0030619)
0.0	0.5	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.1	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	0.1	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.0	0.3	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.1	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.3	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.1	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.1	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.0	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.0	0.1	GO:0035276	alcohol dehydrogenase activity, zinc-dependent(GO:0004024) ethanol binding(GO:0035276)
0.0	0.4	GO:0008483	transaminase activity(GO:0008483)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.0	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0	0.0	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0008948	oxaloacetate decarboxylase activity(GO:0008948)
0.0	0.1	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.1	GO:0047105	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0	0.0	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.3	GO:0052770	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0	0.0	GO:0032551	UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0	0.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.0	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.0	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.0	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.0	0.2	GO:0031492	nucleosomal DNA binding(GO:0031492)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.7	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.2	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.4	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.5	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.0	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.5	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.4	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.3	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.5	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.6	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.7	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.5	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.1	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.4	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.4	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.2	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.3	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels