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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Irx4

Z-value: 1.76

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Transcription factors associated with Irx4

Gene Symbol	Gene ID	Gene Info
Irx4 Ensembl NCBI MGI UniProt	ENSMUSG00000021604.9	Iroquois homeobox 4

Activity of the Irx4 motif across conditions

Conditions sorted by the z-value of the Irx4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr16_80273340_80273491	1.80	Gm23083	predicted gene, 23083	136063	0.05
chr6_128515921_128516189	1.56	Pzp	PZP, alpha-2-macroglobulin like	10648	0.09
chr11_87462456_87462620	1.37	Rnu3b4	U3B small nuclear RNA 4	252	0.83
chr10_19443595_19443775	1.36	Gm33104	predicted gene, 33104	43030	0.15
chr18_10251145_10251313	1.34	Gm5686	predicted gene 5686	10978	0.14
chr3_27909385_27909539	1.29	Tmem212	transmembrane protein 212	13094	0.21
chr8_128687947_128688299	1.27	Itgb1	integrin beta 1 (fibronectin receptor beta)	2253	0.29
chr1_45920584_45920780	1.25	Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	2627	0.2
chr6_35874026_35874908	1.21	Gm43442	predicted gene 43442	52244	0.17
chr7_72345699_72346292	1.20	Mctp2	multiple C2 domains, transmembrane 2	39387	0.21
chr14_78850784_78850948	1.14	Vwa8	von Willebrand factor A domain containing 8	1612	0.36
chr9_83575574_83575734	1.14	Sh3bgrl2	SH3 domain binding glutamic acid-rich protein like 2	1177	0.44
chr1_178330385_178330898	1.11	Hnrnpu	heterogeneous nuclear ribonucleoprotein U	20	0.96
chr19_4588592_4588754	1.09	Pcx	pyruvate carboxylase	5673	0.13
chr13_100544476_100544653	1.08	Ocln	occludin	7896	0.12
chr18_20146742_20147068	1.01	Dsc1	desmocollin 1	32034	0.2
chr6_101351206_101351526	1.00	Gm43946	predicted gene, 43946	2536	0.21
chr1_88975960_88976113	0.97	1700067G17Rik	RIKEN cDNA 1700067G17 gene	40077	0.14
chr14_114418952_114419116	0.97	Gm19829	predicted gene, 19829	108231	0.08
chr5_146079224_146079555	0.96	Cyp3a59	cytochrome P450, family 3, subfamily a, polypeptide 59	122	0.95
chr11_80069895_80070062	0.96	Crlf3	cytokine receptor-like factor 3	10883	0.16
chr13_81314862_81315034	0.96	Adgrv1	adhesion G protein-coupled receptor V1	27888	0.21
chr13_73720273_73720547	0.96	Slc12a7	solute carrier family 12, member 7	12684	0.14
chr6_54438444_54438595	0.95	9130019P16Rik	RIKEN cDNA 9130019P16 gene	8298	0.17
chr4_81591457_81591882	0.95	Gm11411	predicted gene 11411	104772	0.07
chr15_79741187_79741771	0.95	Sun2	Sad1 and UNC84 domain containing 2	613	0.45
chr1_170607667_170608002	0.93	Nos1ap	nitric oxide synthase 1 (neuronal) adaptor protein	17973	0.17
chr8_48944740_48944906	0.93	Gm25830	predicted gene, 25830	13658	0.25
chrX_50956978_50957135	0.93	Frmd7	FERM domain containing 7	14346	0.23
chr4_107899351_107899556	0.93	Czib	CXXC motif containing zinc binding protein	6083	0.13
chr12_79630375_79630621	0.92	9430078K24Rik	RIKEN cDNA 9430078K24 gene	294235	0.01
chr6_15929821_15930118	0.90	Gm43990	predicted gene, 43990	93880	0.08
chr19_38558391_38558564	0.87	Plce1	phospholipase C, epsilon 1	24891	0.22
chr14_64441838_64442032	0.86	Msra	methionine sulfoxide reductase A	1018	0.64
chr11_49996483_49996658	0.84	Rnf130	ring finger protein 130	28776	0.14
chr5_122769447_122769598	0.84	Camkk2	calcium/calmodulin-dependent protein kinase kinase 2, beta	5657	0.14
chr17_30640985_30641153	0.83	Dnah8	dynein, axonemal, heavy chain 8	5313	0.13
chr14_60796696_60796848	0.83	Mipep	mitochondrial intermediate peptidase	12134	0.17
chr17_31569080_31569361	0.83	Gm50107	predicted gene, 50107	2057	0.13
chr1_154149125_154149300	0.81	A830008E24Rik	RIKEN cDNA A830008E24 gene	31261	0.15
chr7_119783443_119783771	0.81	Acsm3	acyl-CoA synthetase medium-chain family member 3	2871	0.15
chr10_38439349_38439537	0.80	Gm48198	predicted gene, 48198	5308	0.32
chr5_27251468_27251639	0.80	Dpp6	dipeptidylpeptidase 6	10422	0.23
chr2_170208965_170209511	0.79	Zfp217	zinc finger protein 217	61135	0.12
chr14_116642069_116642356	0.79	Gm38045	predicted gene, 38045	108003	0.08
chr7_140771376_140771879	0.79	Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	7146	0.09
chr10_43902698_43902849	0.78	Rtn4ip1	reticulon 4 interacting protein 1	966	0.39
chr16_87690672_87690831	0.78	Bach1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	8194	0.22
chrX_38422575_38423072	0.77	Lamp2	lysosomal-associated membrane protein 2	20327	0.15
chr6_31221861_31222046	0.77	Lncpint	long non-protein coding RNA, Trp53 induced transcript	1465	0.3
chr7_105596936_105597272	0.77	Hpx	hemopexin	3008	0.13
chr10_29821551_29821768	0.77	Gm6390	predicted gene 6390	40248	0.18
chr16_91045477_91045695	0.76	4931406G06Rik	RIKEN cDNA 4931406G06 gene	930	0.33
chr3_152208280_152208431	0.76	Dnajb4	DnaJ heat shock protein family (Hsp40) member B4	1664	0.24
chr15_67159040_67159221	0.76	St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	17582	0.24
chr8_13161522_13161685	0.75	Lamp1	lysosomal-associated membrane protein 1	2442	0.16
chr15_62302358_62302526	0.74	Pvt1	Pvt1 oncogene	79839	0.1
chr13_38962916_38963078	0.74	Slc35b3	solute carrier family 35, member B3	2122	0.28
chr16_52267502_52267712	0.74	Alcam	activated leukocyte cell adhesion molecule	1454	0.57
chr6_146765296_146765601	0.74	Gm44270	predicted gene, 44270	2867	0.2
chr2_77155688_77155851	0.73	Ccdc141	coiled-coil domain containing 141	14807	0.21
chr1_58116945_58117096	0.73	Aox3	aldehyde oxidase 3	3834	0.24
chr7_140905824_140905984	0.72	BC024386	cDNA sequence BC023486	110	0.89
chr11_87471532_87471686	0.72	Rnu3b2	U3B small nuclear RNA 2	241	0.85
chr13_41263624_41263896	0.71	Gm17364	predicted gene, 17364	10217	0.13
chr6_9066317_9066493	0.71	Gm35736	predicted gene, 35736	80361	0.11
chr5_142783226_142783546	0.71	Tnrc18	trinucleotide repeat containing 18	5137	0.22
chr10_128566469_128566764	0.70	Pa2g4	proliferation-associated 2G4	629	0.43
chr8_64716760_64716977	0.70	Msmo1	methylsterol monoxygenase 1	5063	0.17
chr11_102138520_102138679	0.68	Nags	N-acetylglutamate synthase	6914	0.08
chr7_130564136_130564299	0.65	Nsmce4a	NSE4 homolog A, SMC5-SMC6 complex component	8901	0.15
chr19_44985292_44985474	0.65	4930414N06Rik	RIKEN cDNA 4930414N06 gene	833	0.43
chr11_16888258_16888409	0.65	Egfr	epidermal growth factor receptor	10183	0.2
chr9_94692147_94692428	0.65	Gm16262	predicted gene 16262	10032	0.17
chr16_15984456_15984622	0.65	n-R5s31	nuclear encoded rRNA 5S 31	26470	0.2
chr16_52249852_52250207	0.65	Alcam	activated leukocyte cell adhesion molecule	19032	0.27
chr1_74059706_74059994	0.65	Tns1	tensin 1	22693	0.18
chr3_28722548_28722883	0.64	Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	1198	0.42
chr5_102599017_102599403	0.64	1700013M08Rik	RIKEN cDNA 1700013M08 gene	115921	0.06
chr7_19695332_19695494	0.63	Apoe	apolipoprotein E	2218	0.12
chr3_22078655_22078806	0.63	Tbl1xr1	transducin (beta)-like 1X-linked receptor 1	1446	0.33
chrX_42065003_42065280	0.63	Xiap	X-linked inhibitor of apoptosis	2695	0.31
chr6_141515419_141515600	0.62	Slco1c1	solute carrier organic anion transporter family, member 1c1	8859	0.27
chr16_43547072_43547244	0.62	Zbtb20	zinc finger and BTB domain containing 20	36850	0.17
chr7_27252126_27252620	0.61	Gm44641	predicted gene 44641	197	0.84
chr2_84650666_84651104	0.61	Ctnnd1	catenin (cadherin associated protein), delta 1	120	0.92
chr1_187476098_187476254	0.61	Gm37896	predicted gene, 37896	28299	0.21
chr19_55087908_55088315	0.60	Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	11340	0.21
chr2_152817536_152817750	0.60	Bcl2l1	BCL2-like 1	10892	0.12
chr15_3483921_3484108	0.60	Ghr	growth hormone receptor	12370	0.28
chr2_134548299_134548473	0.59	Hao1	hydroxyacid oxidase 1, liver	5921	0.31
chr3_24782914_24783090	0.59	Naaladl2	N-acetylated alpha-linked acidic dipeptidase-like 2	620	0.85
chr8_73226959_73227110	0.59	Gm22532	predicted gene, 22532	51776	0.17
chr10_108449802_108449991	0.58	Gm36283	predicted gene, 36283	3294	0.25
chr18_34899168_34899345	0.58	Etf1	eukaryotic translation termination factor 1	32751	0.09
chr15_89396778_89397117	0.58	Klhdc7b	kelch domain containing 7B	10056	0.07
chr10_10408279_10408449	0.58	Adgb	androglobin	3380	0.27
chr7_102224048_102224209	0.58	Pgap2	post-GPI attachment to proteins 2	846	0.48
chr6_138153579_138153750	0.57	Mgst1	microsomal glutathione S-transferase 1	10810	0.28
chr16_24487981_24488183	0.56	Lpp	LIM domain containing preferred translocation partner in lipoma	39991	0.15
chr4_48315210_48315516	0.56	Gm12435	predicted gene 12435	29867	0.16
chr2_65172186_65172346	0.56	Cobll1	Cobl-like 1	63729	0.11
chr4_60659172_60659323	0.56	Mup11	major urinary protein 11	491	0.78
chr5_145986709_145986916	0.56	Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	4831	0.14
chr9_25329643_25329942	0.55	Gm18891	predicted gene, 18891	19706	0.17
chr5_8902050_8902207	0.55	Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	8179	0.15
chr9_60478237_60478388	0.55	Thsd4	thrombospondin, type I, domain containing 4	18814	0.15
chr3_138291566_138291979	0.55	Adh1	alcohol dehydrogenase 1 (class I)	14121	0.11
chr5_121663580_121663743	0.55	Brap	BRCA1 associated protein	1581	0.25
chr5_66095606_66095870	0.55	Rbm47	RNA binding motif protein 47	2453	0.2
chr13_100579015_100579281	0.55	Gm8847	predicted gene 8847	19116	0.1
chr5_32441692_32441843	0.54	Ppp1cb	protein phosphatase 1 catalytic subunit beta	17076	0.11
chr14_27475610_27475797	0.54	Tasor	transcription activation suppressor	1467	0.36
chr1_82974456_82974623	0.54	Gm47955	predicted gene, 47955	14253	0.08
chr3_65991098_65991265	0.54	Gm19024	predicted gene, 19024	1428	0.29
chr2_51512722_51513109	0.54	Gm23505	predicted gene, 23505	19133	0.19
chr4_32538108_32538303	0.54	Bach2os	BTB and CNC homology 2, opposite strand	33412	0.14
chr11_70472894_70473060	0.53	Zmynd15	zinc finger, MYND-type containing 15	12412	0.07
chr15_55265818_55265991	0.53	Gm26296	predicted gene, 26296	3301	0.29
chr1_172827733_172827924	0.53	Gm24817	predicted gene, 24817	15810	0.16
chr13_36681541_36681847	0.53	Gm26395	predicted gene, 26395	27289	0.13
chr4_147406377_147406541	0.52	Gm8178	predicted gene 8178	27530	0.11
chr5_130139764_130139934	0.52	Kctd7	potassium channel tetramerisation domain containing 7	5012	0.13
chr10_89518213_89518404	0.52	Nr1h4	nuclear receptor subfamily 1, group H, member 4	11650	0.21
chr1_190059603_190059918	0.51	Gm28172	predicted gene 28172	108910	0.06
chr4_128969208_128969368	0.51	Azin2	antizyme inhibitor 2	6846	0.16
chr11_104392570_104392977	0.50	Gm47315	predicted gene, 47315	32527	0.14
chr15_61517445_61517596	0.50	Gm49498	predicted gene, 49498	26663	0.25
chr10_30810298_30810917	0.50	Ncoa7	nuclear receptor coactivator 7	7281	0.16
chr6_5223673_5223834	0.50	Gm44250	predicted gene, 44250	3267	0.22
chr7_49751262_49751438	0.50	Htatip2	HIV-1 Tat interactive protein 2	7765	0.22
chr13_112674167_112674325	0.49	Slc38a9	solute carrier family 38, member 9	5875	0.15
chr5_114581477_114581628	0.49	Fam222a	family with sequence similarity 222, member A	13535	0.15
chr17_86593218_86593401	0.49	Gm10309	predicted gene 10309	88077	0.07
chr13_36152416_36152579	0.49	Fars2	phenylalanine-tRNA synthetase 2 (mitochondrial)	22597	0.14
chr5_137481515_137481682	0.49	Epo	erythropoietin	4218	0.09
chr3_104279351_104279517	0.48	Magi3	membrane associated guanylate kinase, WW and PDZ domain containing 3	59060	0.08
chr5_67025062_67025433	0.48	Gm42713	predicted gene 42713	14129	0.12
chr1_184811348_184811540	0.48	Mtarc1	mitochondrial amidoxime reducing component 1	131	0.95
chr14_46017259_46017572	0.47	Gm6580	predicted gene 6580	10013	0.17
chr6_90851681_90851855	0.47	Gm25185	predicted gene, 25185	5769	0.17
chr1_174921018_174921617	0.47	Grem2	gremlin 2, DAN family BMP antagonist	502	0.88
chr16_86826664_86826815	0.47	Gm32624	predicted gene, 32624	9865	0.19
chr4_33262151_33262376	0.47	Pnrc1	proline-rich nuclear receptor coactivator 1	13753	0.16
chr5_77340141_77340310	0.47	Polr2b	polymerase (RNA) II (DNA directed) polypeptide B	143	0.94
chr13_5845761_5845936	0.47	1700016G22Rik	RIKEN cDNA 1700016G22 gene	11713	0.16
chr4_60418791_60418999	0.47	Mup9	major urinary protein 9	1689	0.29
chr3_129867430_129867724	0.47	Pla2g12a	phospholipase A2, group XIIA	11029	0.13
chr13_73730823_73730977	0.47	Slc12a7	solute carrier family 12, member 7	2194	0.26
chr16_48767631_48767807	0.47	Trat1	T cell receptor associated transmembrane adaptor 1	4237	0.22
chr3_146631735_146632069	0.46	Gm16325	predicted gene 16325	10030	0.12
chr3_146604513_146604664	0.46	Uox	urate oxidase	5397	0.14
chr14_76797951_76798124	0.46	Gm30246	predicted gene, 30246	17210	0.17
chr13_30346992_30347295	0.46	Agtr1a	angiotensin II receptor, type 1a	1602	0.41
chr16_71730517_71730728	0.46	Gm22797	predicted gene, 22797	66834	0.13
chr15_8251636_8251790	0.46	Cplane1	ciliogenesis and planar polarity effector 1	4610	0.26
chr1_118458813_118459291	0.46	Gm22710	predicted gene, 22710	213	0.44
chr11_45877769_45877933	0.45	Clint1	clathrin interactor 1	4546	0.19
chr19_12011828_12011982	0.45	Olfr1421-ps1	olfactory receptor 1421, pseudogene 1	8270	0.08
chr3_133530261_133530426	0.45	Tet2	tet methylcytosine dioxygenase 2	13943	0.17
chr11_94637499_94637823	0.45	Lrrc59	leucine rich repeat containing 59	7847	0.1
chr10_94882831_94882985	0.44	Gm48718	predicted gene, 48718	884	0.59
chr13_24363340_24363497	0.44	Gm11342	predicted gene 11342	12532	0.12
chr4_138342269_138342429	0.44	Cda	cytidine deaminase	1300	0.3
chr15_77773367_77773546	0.44	Myh9	myosin, heavy polypeptide 9, non-muscle	3677	0.15
chr5_117275916_117276216	0.44	Pebp1	phosphatidylethanolamine binding protein 1	11459	0.11
chr3_27152202_27152442	0.44	Ect2	ect2 oncogene	1460	0.31
chr12_58323949_58324220	0.44	Clec14a	C-type lectin domain family 14, member a	54794	0.16
chr13_64364897_64365048	0.44	Ctsl	cathepsin L	2083	0.18
chr3_50279626_50279824	0.43	Gm2345	predicted gene 2345	24870	0.22
chr19_32689880_32690046	0.43	Atad1	ATPase family, AAA domain containing 1	4907	0.27
chrX_139113469_139113635	0.43	4930513O06Rik	RIKEN cDNA 4930513O06 gene	27309	0.16
chr7_145044142_145044344	0.43	Ccnd1	cyclin D1	104318	0.05
chr12_71912308_71912620	0.43	Daam1	dishevelled associated activator of morphogenesis 1	22734	0.2
chr15_10308697_10308848	0.43	Prlr	prolactin receptor	5330	0.22
chr15_67044966_67045152	0.43	Gm31342	predicted gene, 31342	5001	0.25
chr2_126950948_126951317	0.43	Sppl2a	signal peptide peptidase like 2A	17897	0.16
chr15_39813920_39814243	0.43	Gm16291	predicted gene 16291	17036	0.19
chr17_44943176_44943431	0.43	4930564C03Rik	RIKEN cDNA 4930564C03 gene	63008	0.13
chr7_26139383_26139621	0.43	Cyp2b26-ps	cytochrome P450, family 2, subfamily b, polypeptide 26, pseudogene	9090	0.15
chr4_101176228_101176401	0.43	Jak1	Janus kinase 1	9111	0.15
chr6_137744823_137744982	0.42	Strap	serine/threonine kinase receptor associated protein	138	0.97
chr4_57525649_57525867	0.42	Pakap	paralemmin A kinase anchor protein	42401	0.16
chr4_35223300_35223499	0.42	C9orf72	C9orf72, member of C9orf72-SMCR8 complex	2435	0.24
chr14_29672536_29672709	0.42	Cacna2d3	calcium channel, voltage-dependent, alpha2/delta subunit 3	49173	0.13
chr12_101080892_101081278	0.42	D130020L05Rik	RIKEN cDNA D130020L05 gene	1366	0.29
chr13_41112373_41112548	0.42	Gcm2	glial cells missing homolog 2	1425	0.28
chr15_89210520_89210683	0.42	Ppp6r2	protein phosphatase 6, regulatory subunit 2	952	0.39
chr18_20939203_20939371	0.42	Rnf125	ring finger protein 125	5338	0.23
chr1_140406769_140406932	0.42	Kcnt2	potassium channel, subfamily T, member 2	36086	0.22
chr19_5433656_5433971	0.42	Gm50111	predicted gene, 50111	2087	0.09
chr8_126838292_126838477	0.41	A630001O12Rik	RIKEN cDNA A630001O12 gene	849	0.65
chr17_55513425_55513584	0.41	St6gal2	beta galactoside alpha 2,6 sialyltransferase 2	67260	0.1
chr1_164215221_164215636	0.41	Slc19a2	solute carrier family 19 (thiamine transporter), member 2	33618	0.11
chr13_80882069_80882492	0.41	Arrdc3	arrestin domain containing 3	1104	0.47
chr3_102670542_102670863	0.41	Gm19202	predicted gene, 19202	16015	0.14
chr1_161269196_161269347	0.41	Prdx6	peroxiredoxin 6	18052	0.16
chr13_28874054_28874215	0.41	2610307P16Rik	RIKEN cDNA 2610307P16 gene	9322	0.18
chr15_55224563_55224882	0.41	Gm26296	predicted gene, 26296	37881	0.16
chr2_154820458_154820609	0.40	Raly	hnRNP-associated with lethal yellow	28818	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Irx4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0010912	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.1	0.4	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.1	0.4	GO:0060300	regulation of cytokine activity(GO:0060300)
0.1	0.4	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.4	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1	0.5	GO:0030091	protein repair(GO:0030091)
0.1	0.6	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.1	0.3	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1	0.4	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.3	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.1	0.2	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.1	0.2	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.1	0.3	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.2	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.2	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.1	0.3	GO:0016078	tRNA catabolic process(GO:0016078)
0.1	0.2	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.1	0.4	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.1	0.2	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.1	0.3	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.2	GO:0061084	negative regulation of protein refolding(GO:0061084)
0.1	0.3	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1	0.5	GO:0090520	sphingolipid mediated signaling pathway(GO:0090520)
0.1	0.2	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0	0.1	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.2	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.1	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	0.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.3	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.2	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.1	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.0	0.1	GO:0006216	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0014016	neuroblast differentiation(GO:0014016)
0.0	0.2	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.4	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.1	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.0	0.1	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.2	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.0	0.2	GO:2001280	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0	0.2	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.3	GO:0090232	positive regulation of spindle checkpoint(GO:0090232)
0.0	0.1	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0	0.1	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.1	GO:0033668	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0	0.1	GO:0006172	ADP biosynthetic process(GO:0006172)
0.0	0.1	GO:0015888	thiamine transport(GO:0015888)
0.0	0.1	GO:0060336	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.2	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.1	GO:0061144	alveolar secondary septum development(GO:0061144)
0.0	0.2	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0	0.1	GO:0035910	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0	0.3	GO:0007097	nuclear migration(GO:0007097)
0.0	0.2	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.1	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.1	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0	0.1	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.1	GO:0097475	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0048143	astrocyte activation(GO:0048143)
0.0	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.0	0.1	GO:1990791	dorsal root ganglion development(GO:1990791)
0.0	0.1	GO:2000173	negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.3	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.1	GO:1902996	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.0	0.1	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0	0.1	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045)
0.0	0.1	GO:0061316	canonical Wnt signaling pathway involved in heart development(GO:0061316)
0.0	0.1	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.1	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.0	0.1	GO:1902218	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0	0.3	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0	0.1	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.4	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.0	0.1	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.0	0.1	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0	0.1	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0	0.2	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.1	GO:0002894	type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type IIa hypersensitivity(GO:0001798) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) positive regulation of type II hypersensitivity(GO:0002894)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.1	GO:0051890	regulation of cardioblast differentiation(GO:0051890)
0.0	0.7	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.1	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.0	0.1	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0	0.2	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.0	0.1	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.0	0.1	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.1	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.0	GO:0043622	cortical microtubule organization(GO:0043622)
0.0	0.4	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0	0.1	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.1	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.0	0.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.1	GO:0006524	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.2	GO:0060546	negative regulation of necroptotic process(GO:0060546)
0.0	0.1	GO:1903750	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0	0.0	GO:0021593	rhombomere morphogenesis(GO:0021593)
0.0	0.2	GO:0002329	pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0030953	astral microtubule organization(GO:0030953)
0.0	0.2	GO:0042635	positive regulation of hair cycle(GO:0042635)
0.0	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.1	GO:0042117	monocyte activation(GO:0042117)
0.0	0.1	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.0	GO:1901166	neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.5	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.1	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.0	GO:1903423	positive regulation of synaptic vesicle recycling(GO:1903423)
0.0	0.1	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.0	0.1	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.0	0.0	GO:0019448	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0	0.1	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.0	GO:0003164	His-Purkinje system development(GO:0003164) bundle of His development(GO:0003166)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0090214	spongiotrophoblast layer developmental growth(GO:0090214)
0.0	0.1	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:1905208	negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.0	0.1	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.1	GO:0072429	response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0	0.2	GO:0006517	protein deglycosylation(GO:0006517)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.0	GO:0060128	corticotropin hormone secreting cell differentiation(GO:0060128)
0.0	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0060696	regulation of phospholipid catabolic process(GO:0060696)
0.0	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.1	GO:0009838	abscission(GO:0009838)
0.0	0.2	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0007343	egg activation(GO:0007343)
0.0	0.4	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.0	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.0	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0	0.0	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.1	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.2	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0070126	mitochondrial translational termination(GO:0070126)
0.0	0.0	GO:0007418	ventral midline development(GO:0007418)
0.0	0.1	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.0	0.0	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.1	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.0	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0	0.0	GO:0015817	histidine transport(GO:0015817)
0.0	0.1	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.0	0.0	GO:0002525	acute inflammatory response to non-antigenic stimulus(GO:0002525)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0006415	translational termination(GO:0006415)
0.0	0.1	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.0	GO:0023021	termination of signal transduction(GO:0023021)
0.0	0.0	GO:0015755	fructose transport(GO:0015755)
0.0	0.0	GO:0061687	detoxification of inorganic compound(GO:0061687)
0.0	0.1	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.0	0.0	GO:0007403	glial cell fate determination(GO:0007403)
0.0	0.1	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.0	0.4	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.1	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.0	0.1	GO:0061050	regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.0	0.1	GO:0046051	UTP metabolic process(GO:0046051)
0.0	0.0	GO:0033029	regulation of neutrophil apoptotic process(GO:0033029)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.0	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
0.0	0.0	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.0	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.2	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.0	0.2	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.0	GO:0035262	gonad morphogenesis(GO:0035262)
0.0	0.0	GO:0033686	positive regulation of luteinizing hormone secretion(GO:0033686)
0.0	0.0	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:0033483	gas homeostasis(GO:0033483)
0.0	0.1	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373)
0.0	0.1	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.1	GO:0015867	ATP transport(GO:0015867)
0.0	0.2	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.0	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0	0.0	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.1	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.0	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.0	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.0	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.0	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0043545	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.0	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.0	0.0	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242)
0.0	0.0	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0	0.2	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
0.0	0.0	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.0	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.0	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.2	GO:0002021	response to dietary excess(GO:0002021)
0.0	0.1	GO:0046040	IMP metabolic process(GO:0046040)
0.0	0.0	GO:0044800	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.0	GO:0050883	medulla oblongata development(GO:0021550) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0	0.0	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.0	0.0	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.0	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.1	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.0	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.0	0.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.0	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0	0.0	GO:0034241	positive regulation of macrophage fusion(GO:0034241)
0.0	0.0	GO:0099515	actin filament-based transport(GO:0099515)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0009115	xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	0.4	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.1	0.4	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.1	0.3	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1	0.6	GO:0005915	zonula adherens(GO:0005915)
0.1	0.3	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.4	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0097543	ciliary inversin compartment(GO:0097543)
0.0	0.3	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.1	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.2	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.2	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.4	GO:0032797	SMN complex(GO:0032797)
0.0	0.2	GO:1990696	USH2 complex(GO:1990696)
0.0	0.2	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.2	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.2	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.6	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.2	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.1	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.3	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0	0.5	GO:0030057	desmosome(GO:0030057)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.2	GO:0042627	chylomicron(GO:0042627)
0.0	0.1	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.0	GO:1990812	growth cone filopodium(GO:1990812)
0.0	0.3	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.3	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.1	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.0	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0043219	lateral loop(GO:0043219)
0.0	0.1	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	0.1	GO:0005818	aster(GO:0005818)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.1	GO:0070847	core mediator complex(GO:0070847)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.0	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.1	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.0	0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.1	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.1	GO:1990745	EARP complex(GO:1990745)
0.0	0.0	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.0	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0000805	X chromosome(GO:0000805)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.2	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.0	GO:0031429	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0	0.0	GO:0097443	sorting endosome(GO:0097443)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.0	GO:0032127	dense core granule membrane(GO:0032127)
0.0	0.0	GO:0032437	cuticular plate(GO:0032437)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.0	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.0	0.0	GO:0071953	elastic fiber(GO:0071953)
0.0	0.3	GO:0008305	integrin complex(GO:0008305)
0.0	0.0	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.0	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	0.1	GO:0060091	kinocilium(GO:0060091)
0.0	0.0	GO:0000811	GINS complex(GO:0000811)
0.0	0.0	GO:0036488	CHOP-C/EBP complex(GO:0036488)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.1	GO:0008390	testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.1	1.0	GO:0034046	poly(G) binding(GO:0034046)
0.1	0.4	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.1	0.3	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1	0.3	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1	0.4	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1	0.5	GO:0018647	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.1	0.2	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1	0.2	GO:0031711	bradykinin receptor binding(GO:0031711)
0.1	0.3	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	0.2	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1	0.5	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1	0.2	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.1	0.4	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.2	GO:0005346	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.3	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.2	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	0.4	GO:0036122	BMP binding(GO:0036122)
0.0	0.2	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.2	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.4	GO:0001055	RNA polymerase II activity(GO:0001055)
0.0	0.1	GO:0035877	death effector domain binding(GO:0035877)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.2	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.2	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.2	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.2	GO:0070728	leucine binding(GO:0070728)
0.0	0.1	GO:0048408	epidermal growth factor binding(GO:0048408)
0.0	0.2	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.0	0.1	GO:0032564	dATP binding(GO:0032564)
0.0	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0102344	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0034618	arginine binding(GO:0034618)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.2	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.0	0.2	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.0	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.4	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.1	GO:0019770	IgG receptor activity(GO:0019770)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.1	GO:0030984	kininogen binding(GO:0030984)
0.0	0.0	GO:0019959	interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.1	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.2	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.2	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.7	GO:0045296	cadherin binding(GO:0045296)
0.0	0.1	GO:0070905	serine binding(GO:0070905)
0.0	0.1	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.3	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.3	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.2	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.1	GO:0035939	microsatellite binding(GO:0035939)
0.0	0.4	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.3	GO:0031690	adrenergic receptor binding(GO:0031690)
0.0	0.0	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0045340	mercury ion binding(GO:0045340)
0.0	0.3	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.1	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.0	GO:0015182	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.0	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.0	0.2	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0052759	4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.0	0.2	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.0	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.3	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.0	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.3	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0031782	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0004031	aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.0	GO:0008948	oxaloacetate decarboxylase activity(GO:0008948)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.0	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0	0.0	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.0	0.1	GO:0034863	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0	0.0	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.0	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.0	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.2	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.0	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.2	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.0	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.0	0.3	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.8	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.7	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.6	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.4	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.6	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.4	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.2	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	1.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.2	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.0	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.1	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.0	REACTOME DNA STRAND ELONGATION	Genes involved in DNA strand elongation

Results for Irx4

Z-value: 1.76

Motif logo

Transcription factors associated with Irx4

Activity of the Irx4 motif across conditions

Conditions sorted by the z-value of the Irx4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Irx4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: