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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Klf13

Z-value: 0.97

Motif logo

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Transcription factors associated with Klf13

Gene Symbol Gene ID Gene Info
Klf13
ENSMUSG00000052040.9 Kruppel-like factor 13

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_63934853_63935097Klf1313260.339936-0.833.9e-02Click!
chr7_63930850_63931034Klf1353590.144137-0.805.5e-02Click!
chr7_63928069_63928220Klf1332740.172344-0.739.8e-02Click!
chr7_63924758_63924944Klf13190.966664-0.721.0e-01Click!
chr7_63936513_63936685Klf132670.876987-0.671.5e-01Click!

Activity of the Klf13 motif across conditions

Conditions sorted by the z-value of the Klf13 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_139020930_139021245 2.06 Gm45613
 predicted gene 45613
 88
 0.97
chr10_95720533_95720688 0.88 1110019B22Rik
 RIKEN cDNA 1110019B22 gene
 1879
 0.2
chr7_66005228_66005393 0.66 Pcsk6
 proprotein convertase subtilisin/kexin type 6
 33108
 0.12
chrY_90739212_90739561 0.60 Mid1-ps1
 midline 1, pseudogene 1
 13671
 0.18
chr4_35134107_35134262 0.57 Ifnk
 interferon kappa
 17872
 0.17
chr17_14175138_14175307 0.54 Gm34510
 predicted gene, 34510
 28506
 0.14
chr11_67081331_67081503 0.48 Myh3
 myosin, heavy polypeptide 3, skeletal muscle, embryonic
 3117
 0.17
chr11_97428221_97428386 0.46 Arhgap23
 Rho GTPase activating protein 23
 7982
 0.16
chr8_71559035_71559219 0.45 Tmem221
 transmembrane protein 221
 256
 0.79
chr6_90486122_90486491 0.44 Gm45901
 predicted gene 45901
 87
 0.54
chr6_148212064_148212226 0.44 Ergic2
 ERGIC and golgi 2
 38
 0.58
chr5_38560875_38561037 0.40 Wdr1
 WD repeat domain 1
 587
 0.71
chr4_150874506_150874750 0.39 Errfi1
 ERBB receptor feedback inhibitor 1
 19555
 0.12
chr17_29841749_29841925 0.39 Mdga1
 MAM domain containing glycosylphosphatidylinositol anchor 1
 584
 0.73
chr10_117418076_117418301 0.37 Gm40770
 predicted gene, 40770
 4284
 0.16
chr16_22919975_22920126 0.36 Fetub
 fetuin beta
 187
 0.91
chr18_60603591_60603778 0.35 Synpo
 synaptopodin
 3187
 0.2
chr6_116195979_116196139 0.34 Gm8213
 predicted pseudogene 8213
 201
 0.89
chr3_105893960_105894139 0.34 Adora3
 adenosine A3 receptor
 10372
 0.12
chr2_158176890_158177041 0.34 1700060C20Rik
 RIKEN cDNA 1700060C20 gene
 15043
 0.14
chr1_191186557_191186730 0.33 Atf3
 activating transcription factor 3
 3303
 0.18
chr7_80156693_80156942 0.33 Gm45202
 predicted gene 45202
 1648
 0.25
chr4_133804499_133804683 0.32 Gm25270
 predicted gene, 25270
 6872
 0.14
chr1_182585565_182585739 0.31 Capn8
 calpain 8
 20614
 0.16
chr15_31338782_31338933 0.31 Ankrd33b
 ankyrin repeat domain 33B
 13608
 0.15
chr2_85047886_85048056 0.30 Tnks1bp1
 tankyrase 1 binding protein 1
 51
 0.96
chr4_47245499_47245708 0.30 Col15a1
 collagen, type XV, alpha 1
 12336
 0.2
chr19_44997151_44997302 0.28 Sema4g
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
 5090
 0.11
chr17_83503811_83503975 0.28 Cox7a2l
 cytochrome c oxidase subunit 7A2 like
 613
 0.8
chr7_27178957_27179117 0.27 Rab4b
 RAB4B, member RAS oncogene family
 141
 0.86
chr9_31211792_31211960 0.27 Aplp2
 amyloid beta (A4) precursor-like protein 2
 61
 0.98
chr12_14152257_14152408 0.27 Lratd1
 LRAT domain containing 1
 278
 0.93
chr10_80168459_80168625 0.26 Cirbp
 cold inducible RNA binding protein
 656
 0.47
chr2_167014815_167015114 0.26 Ddx27
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
 229
 0.87
chr13_98689660_98689822 0.26 Tmem171
 transmembrane protein 171
 5027
 0.15
chr11_69326130_69326304 0.26 Kcnab3
 potassium voltage-gated channel, shaker-related subfamily, beta member 3
 41
 0.93
chr15_99113382_99113533 0.26 Spats2
 spermatogenesis associated, serine-rich 2
 12459
 0.09
chrX_8252648_8252921 0.26 Ftsj1
 FtsJ RNA methyltransferase homolog 1 (E. coli)
 378
 0.8
chr2_170155421_170155732 0.25 Zfp217
 zinc finger protein 217
 7473
 0.29
chr1_39192284_39192607 0.25 Npas2
 neuronal PAS domain protein 2
 1286
 0.45
chr8_94012059_94012219 0.25 Amfr
 autocrine motility factor receptor
 12
 0.97
chr5_129895249_129895421 0.25 Zbed5
 zinc finger, BED type containing 5
 388
 0.71
chr11_117836449_117836615 0.24 Afmid
 arylformamidase
 4259
 0.1
chr5_115732580_115732733 0.24 Bicdl1
 BICD family like cargo adaptor 1
 1035
 0.52
chr9_94155767_94155925 0.24 Gm5369
 predicted gene 5369
 16384
 0.29
chr3_142709083_142709286 0.24 Kyat3
 kynurenine aminotransferase 3
 8090
 0.14
chr7_19665320_19665478 0.23 Clptm1
 cleft lip and palate associated transmembrane protein 1
 366
 0.7
chr10_79908555_79908720 0.23 Med16
 mediator complex subunit 16
 181
 0.71
chr15_78340778_78340947 0.22 Mir7676-2
 microRNA 7676-2
 7737
 0.12
chr7_16874839_16875265 0.22 9330104G04Rik
 RIKEN cDNA 9330104G04 gene
 166
 0.6
chr1_35931118_35931293 0.22 Gm8022
 predicted gene 8022
 27714
 0.14
chr5_74704572_74704742 0.22 Gm15984
 predicted gene 15984
 1637
 0.29
chr9_107289789_107289967 0.22 Mapkapk3
 mitogen-activated protein kinase-activated protein kinase 3
 1
 0.95
chr5_114826323_114826479 0.22 Ywhaq-ps2
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta, pseudogene 2
 2814
 0.12
chr17_31519992_31520147 0.21 Ndufv3
 NADH:ubiquinone oxidoreductase core subunit V3
 46
 0.53
chr3_39220041_39220211 0.21 Gm43008
 predicted gene 43008
 2280
 0.42
chr7_27447795_27447954 0.21 Blvrb
 biliverdin reductase B (flavin reductase (NADPH))
 104
 0.61
chr17_84879283_84879445 0.21 Gm49982
 predicted gene, 49982
 23205
 0.14
chr12_21145146_21145377 0.20 Asap2
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
 33307
 0.16
chr6_4086907_4087076 0.20 Bet1
 Bet1 golgi vesicular membrane trafficking protein
 19
 0.98
chr2_38519062_38519254 0.20 Nek6
 NIMA (never in mitosis gene a)-related expressed kinase 6
 4532
 0.14
chr2_152707734_152707946 0.20 H13
 histocompatibility 13
 16001
 0.09
chr19_4300270_4300606 0.20 Grk2
 G protein-coupled receptor kinase 2
 4770
 0.1
chr15_67039473_67039636 0.20 Gm31342
 predicted gene, 31342
 504
 0.83
chr1_188858745_188858917 0.19 Ush2a
 usherin
 94913
 0.08
chr9_120582294_120582487 0.19 Gm47062
 predicted gene, 47062
 2255
 0.19
chr2_73892795_73892960 0.19 Atf2
 activating transcription factor 2
 238
 0.93
chr6_140874934_140875096 0.19 Gm30524
 predicted gene, 30524
 80594
 0.09
chr1_118627791_118627969 0.19 Tfcp2l1
 transcription factor CP2-like 1
 65
 0.97
chr10_95193833_95194034 0.18 Gm48874
 predicted gene, 48874
 33572
 0.14
chr6_82652519_82652678 0.18 Pole4
 polymerase (DNA-directed), epsilon 4 (p12 subunit)
 78
 0.97
chr8_71272393_71272552 0.18 Haus8
 4HAUS augmin-like complex, subunit 8
 6
 0.77
chr17_35909704_35909977 0.18 Atat1
 alpha tubulin acetyltransferase 1
 101
 0.88
chrY_90740044_90740606 0.18 Mid1-ps1
 midline 1, pseudogene 1
 12732
 0.18
chr16_96127966_96128133 0.18 Hmgn1
 high mobility group nucleosomal binding domain 1
 320
 0.83
chr4_119223756_119224101 0.18 Gm12898
 predicted gene 12898
 754
 0.42
chr1_165763620_165763778 0.18 Creg1
 cellular repressor of E1A-stimulated genes 1
 47
 0.95
chr18_12941778_12941952 0.17 Osbpl1a
 oxysterol binding protein-like 1A
 24
 0.98
chr14_51884664_51884952 0.17 Mettl17
 methyltransferase like 17
 34
 0.94
chr17_55956278_55956439 0.17 Yju2
 YJU2 splicing factor
 2741
 0.11
chr2_34897940_34898106 0.17 Phf19
 PHD finger protein 19
 6129
 0.11
chr3_9038418_9038576 0.17 Gm37616
 predicted gene, 37616
 8995
 0.17
chr4_123686928_123687079 0.17 Macf1
 microtubule-actin crosslinking factor 1
 2643
 0.2
chr4_43442956_43443142 0.17 Tesk1
 testis specific protein kinase 1
 272
 0.82
chr15_88837187_88837359 0.17 Gm23144
 predicted gene, 23144
 1973
 0.24
chr15_12248377_12248536 0.17 Mtmr12
 myotubularin related protein 12
 25102
 0.12
chr5_113219993_113220303 0.17 2900026A02Rik
 RIKEN cDNA 2900026A02 gene
 1088
 0.42
chr1_136008248_136008409 0.17 Tmem9
 transmembrane protein 9
 178
 0.92
chr1_42474261_42474413 0.17 Gm37047
 predicted gene, 37047
 17476
 0.25
chr9_44327277_44327612 0.16 Dpagt1
 dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
 539
 0.46
chr15_67110643_67110805 0.16 St3gal1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 3268
 0.32
chr4_134796652_134796803 0.16 Maco1
 macoilin 1
 14486
 0.18
chr2_163308491_163308647 0.16 Tox2
 TOX high mobility group box family member 2
 11809
 0.2
chr8_84707765_84707923 0.16 Nfix
 nuclear factor I/X
 128
 0.92
chr4_43040334_43040495 0.16 Fam214b
 family with sequence similarity 214, member B
 119
 0.93
chr7_45714696_45714867 0.16 Sphk2
 sphingosine kinase 2
 426
 0.47
chr16_30512503_30512806 0.16 Tmem44
 transmembrane protein 44
 28255
 0.16
chr12_100958810_100958969 0.15 Ccdc88c
 coiled-coil domain containing 88C
 13716
 0.12
chr19_5118250_5118577 0.15 Klc2
 kinesin light chain 2
 113
 0.76
chr11_59787617_59787784 0.15 Pld6
 phospholipase D family, member 6
 55
 0.95
chr1_184732600_184732772 0.15 Hlx
 H2.0-like homeobox
 67
 0.96
chr12_52314917_52315090 0.15 Gm47431
 predicted gene, 47431
 133122
 0.04
chr14_47189631_47189815 0.15 Gch1
 GTP cyclohydrolase 1
 310
 0.8
chr15_62203372_62203523 0.15 Pvt1
 Pvt1 oncogene
 14776
 0.23
chrX_150813018_150813184 0.14 Maged2
 melanoma antigen, family D, 2
 23
 0.97
chr9_21265122_21265283 0.14 Atg4d
 autophagy related 4D, cysteine peptidase
 91
 0.93
chr10_24830554_24830712 0.14 Enpp3
 ectonucleotide pyrophosphatase/phosphodiesterase 3
 1173
 0.49
chr13_49216001_49216172 0.14 Card19
 caspase recruitment domain family, member 19
 49
 0.97
chr7_19811188_19811394 0.14 Bcl3
 B cell leukemia/lymphoma 3
 598
 0.46
chr11_119238465_119238619 0.14 Ccdc40
 coiled-coil domain containing 40
 176
 0.92
chr2_167538011_167538171 0.14 Snai1
 snail family zinc finger 1
 104
 0.94
chr17_47438043_47438256 0.14 1700001C19Rik
 RIKEN cDNA 1700001C19 gene
 773
 0.44
chr17_87282754_87282914 0.14 4833418N02Rik
 RIKEN cDNA 4833418N02 gene
 20
 0.52
chr5_138280001_138280359 0.14 Stag3
 stromal antigen 3
 60
 0.52
chr7_25619112_25619443 0.14 Dmac2
 distal membrane arm assembly complex 2
 137
 0.9
chr4_156197972_156198140 0.14 Agrn
 agrin
 568
 0.56
chr10_61492177_61492335 0.14 Gm47595
 predicted gene, 47595
 4034
 0.12
chr8_72239914_72240076 0.13 Ap1m1
 adaptor-related protein complex AP-1, mu subunit 1
 23
 0.95
chr9_119100530_119100792 0.13 Dlec1
 deleted in lung and esophageal cancer 1
 1817
 0.25
chr11_5445001_5445157 0.13 Znrf3
 zinc and ring finger 3
 232
 0.93
chr8_125199868_125200019 0.13 Gm16237
 predicted gene 16237
 27380
 0.22
chr7_16313428_16313735 0.13 Bbc3
 BCL2 binding component 3
 64
 0.96
chr11_67025097_67025255 0.13 Tmem220
 transmembrane protein 220
 22
 0.97
chr14_30916422_30916581 0.13 Itih3
 inter-alpha trypsin inhibitor, heavy chain 3
 1114
 0.35
chr10_40257637_40257797 0.13 Gtf3c6
 general transcription factor IIIC, polypeptide 6, alpha
 41
 0.92
chr12_4874314_4874496 0.12 Mfsd2b
 major facilitator superfamily domain containing 2B
 46
 0.96
chr4_152108046_152108214 0.12 Plekhg5
 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
 401
 0.76
chr2_172826555_172826706 0.12 Gm22773
 predicted gene, 22773
 37711
 0.18
chr8_57488604_57488764 0.12 2500002B13Rik
 RIKEN cDNA 2500002B13 gene
 630
 0.45
chr8_94876193_94876353 0.12 Dok4
 docking protein 4
 57
 0.95
chr11_75247267_75247439 0.12 Rtn4rl1
 reticulon 4 receptor-like 1
 53570
 0.07
chr19_29325385_29325550 0.12 Insl6
 insulin-like 6
 111
 0.95
chr7_19228690_19228852 0.12 Opa3
 optic atrophy 3
 388
 0.68
chr7_19118353_19118670 0.12 Gm4969
 predicted gene 4969
 143
 0.87
chr11_23254748_23254899 0.12 Xpo1
 exportin 1
 1218
 0.51
chr10_76531437_76531608 0.12 Lss
 lanosterol synthase
 66
 0.96
chr8_94183220_94183416 0.12 Gm39228
 predicted gene, 39228
 29
 0.95
chr12_8921530_8921697 0.12 Laptm4a
 lysosomal-associated protein transmembrane 4A
 51
 0.97
chr7_44858030_44858203 0.12 Pnkp
 polynucleotide kinase 3'- phosphatase
 380
 0.64
chr9_44515546_44515772 0.11 Cxcr5
 chemokine (C-X-C motif) receptor 5
 10762
 0.07
chr15_9072830_9073005 0.11 Nadk2
 NAD kinase 2, mitochondrial
 1230
 0.52
chr3_145556330_145556492 0.11 Col24a1
 collagen, type XXIV, alpha 1
 11438
 0.2
chr8_36377048_36377257 0.11 Gm5787
 predicted gene 5787
 3519
 0.25
chr17_65951168_65951335 0.11 Twsg1
 twisted gastrulation BMP signaling modulator 1
 25
 0.97
chr13_94177289_94177442 0.11 Lhfpl2
 lipoma HMGIC fusion partner-like 2
 3373
 0.25
chr2_32751402_32751562 0.11 Tor2a
 torsin family 2, member A
 5752
 0.08
chr11_75047480_75047670 0.11 Gm12333
 predicted gene 12333
 8227
 0.13
chr11_113684528_113684688 0.11 D11Wsu47e
 DNA segment, Chr 11, Wayne State University 47, expressed
 161
 0.77
chr13_13954579_13954776 0.11 B3galnt2
 UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2
 3
 0.96
chr8_64946983_64947186 0.11 Tmem192
 transmembrane protein 192
 101
 0.88
chr2_35336999_35337164 0.11 Stom
 stomatin
 105
 0.95
chr14_46832037_46832198 0.11 Cgrrf1
 cell growth regulator with ring finger domain 1
 8
 0.56
chr17_56627213_56627375 0.11 Lonp1
 lon peptidase 1, mitochondrial
 407
 0.62
chr15_10675955_10676106 0.11 Rai14
 retinoic acid induced 14
 37510
 0.14
chr9_18473377_18473557 0.11 Zfp558
 zinc finger protein 558
 45
 0.96
chr8_95293260_95293422 0.11 Cngb1
 cyclic nucleotide gated channel beta 1
 328
 0.85
chr9_21918187_21918359 0.11 Rab3d
 RAB3D, member RAS oncogene family
 81
 0.93
chrX_73967268_73967441 0.11 Hcfc1
 host cell factor C1
 997
 0.39
chr10_21420912_21421063 0.11 1700021A07Rik
 RIKEN cDNA 1700021A07 gene
 1510
 0.3
chr10_59951771_59951950 0.10 Ddit4
 DNA-damage-inducible transcript 4
 26
 0.98
chr14_122105762_122105950 0.10 A330035P11Rik
 RIKEN cDNA A330035P11 gene
 1097
 0.31
chr4_155469018_155469192 0.10 Tmem52
 transmembrane protein 52
 9
 0.96
chr14_63164949_63165115 0.10 Fdft1
 farnesyl diphosphate farnesyl transferase 1
 107
 0.96
chr16_22899718_22899927 0.10 Ahsg
 alpha-2-HS-glycoprotein
 4958
 0.13
chr10_80577406_80577585 0.10 Klf16
 Kruppel-like factor 16
 174
 0.87
chr11_51856076_51856454 0.10 Jade2
 jade family PHD finger 2
 860
 0.59
chr3_90509502_90509661 0.10 Chtop
 chromatin target of PRMT1
 83
 0.92
chr13_95894500_95894710 0.10 Iqgap2
 IQ motif containing GTPase activating protein 2
 2122
 0.3
chr15_79774430_79774597 0.10 Dnal4
 dynein, axonemal, light chain 4
 46
 0.95
chr16_57167289_57167444 0.10 Nit2
 nitrilase family, member 2
 25
 0.5
chr1_74721665_74721828 0.10 Cyp27a1
 cytochrome P450, family 27, subfamily a, polypeptide 1
 8172
 0.13
chr7_115948051_115948232 0.10 Sox6
 SRY (sex determining region Y)-box 6
 46945
 0.13
chr17_56079134_56079310 0.09 Hdgfl2
 HDGF like 2
 412
 0.69
chr4_132329477_132329639 0.09 Trnau1ap
 tRNA selenocysteine 1 associated protein 1
 20
 0.92
chr8_83608021_83608180 0.09 Dnajb1
 DnaJ heat shock protein family (Hsp40) member B1
 93
 0.54
chr9_57295766_57295926 0.09 1700017B05Rik
 RIKEN cDNA 1700017B05 gene
 33234
 0.11
chr12_21286198_21286361 0.09 Itgb1bp1
 integrin beta 1 binding protein 1
 5
 0.55
chr1_105990177_105990357 0.09 Gm7160
 predicted gene 7160
 15
 0.64
chr4_104975117_104975442 0.09 Gm12721
 predicted gene 12721
 5150
 0.27
chr11_59191846_59192317 0.09 Guk1
 guanylate kinase 1
 129
 0.91
chr2_11535513_11535687 0.09 Gm37975
 predicted gene, 37975
 906
 0.49
chr10_119614856_119615049 0.09 Gm47027
 predicted gene, 47027
 2768
 0.28
chr10_81320325_81320502 0.09 Cactin
 cactin, spliceosome C complex subunit
 690
 0.37
chr7_29170009_29170256 0.09 Ggn
 gametogenetin
 78
 0.73
chr3_108467871_108468033 0.09 5330417C22Rik
 RIKEN cDNA 5330417C22 gene
 2129
 0.16
chr5_144358410_144358608 0.09 Dmrt1i
 Dmrt1 interacting ncRNA
 16
 0.87
chr8_125133982_125134146 0.09 Disc1
 disrupted in schizophrenia 1
 46077
 0.14
chr8_126516634_126516823 0.09 Gm6091
 predicted pseudogene 6091
 40316
 0.14
chr11_16803990_16804532 0.09 Egfros
 epidermal growth factor receptor, opposite strand
 26441
 0.18
chr6_90395849_90396012 0.09 C030015A19Rik
 RIKEN cDNA C030015A19 gene
 9123
 0.12
chr12_86825129_86825313 0.09 Gm10095
 predicted gene 10095
 21246
 0.17
chr17_25474786_25474993 0.09 Tekt4
 tektin 4
 585
 0.6
chr7_30626129_30626287 0.09 Cox6b1
 cytochrome c oxidase, subunit 6B1
 57
 0.91
chr17_84875170_84875325 0.09 Gm9400
 predicted gene 9400
 22709
 0.14
chr17_80004938_80005095 0.09 Gm41625
 predicted gene, 41625
 23354
 0.13
chr1_195092267_195092425 0.09 Cd46
 CD46 antigen, complement regulatory protein
 97
 0.95
chr7_99828286_99828448 0.09 Neu3
 neuraminidase 3
 50
 0.96
chr4_133085038_133085232 0.09 Ahdc1
 AT hook, DNA binding motif, containing 1
 18886
 0.17
chr14_31641238_31641408 0.09 Hacl1
 2-hydroxyacyl-CoA lyase 1
 37
 0.72
chr9_26923072_26923237 0.08 Gm1110
 predicted gene 1110
 43
 0.97

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.2 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.2 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 0.1 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.3 GO:0030836 positive regulation of actin filament depolymerization(GO:0030836)
0.0 0.1 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.1 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0 0.1 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.0 0.1 GO:1903121 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.2 GO:0032906 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0 0.1 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.0 0.3 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.3 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.2 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.0 0.1 GO:1903273 regulation of sodium ion export(GO:1903273) regulation of sodium ion export from cell(GO:1903276)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.0 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 0.2 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.0 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.0 GO:0019042 viral latency(GO:0019042)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.0 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.2 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.0 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0045820 negative regulation of glycolytic process(GO:0045820)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.4 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.1 GO:0009437 carnitine metabolic process(GO:0009437)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0000802 transverse filament(GO:0000802)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.0 GO:0033647 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0 0.0 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.0 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0019145 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.1 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0 0.2 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0003933 GTP cyclohydrolase activity(GO:0003933)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0052796 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.0 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.0 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0031559 oxidosqualene cyclase activity(GO:0031559)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.0 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.0 GO:0089720 death effector domain binding(GO:0035877) caspase binding(GO:0089720)
0.0 0.0 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.0 GO:0016018 cyclosporin A binding(GO:0016018)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.0 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins