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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Klf13

Z-value: 0.97

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Transcription factors associated with Klf13

Gene Symbol	Gene ID	Gene Info
Klf13 Ensembl NCBI MGI UniProt	ENSMUSG00000052040.9	Klf13

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Klf13	chr7_63934853_63935097	1326	0.339936	-0.83	3.9e-02	Click!
Klf13	chr7_63930850_63931034	5359	0.144137	-0.80	5.5e-02	Click!
Klf13	chr7_63928069_63928220	3274	0.172344	-0.73	9.8e-02	Click!
Klf13	chr7_63924758_63924944	19	0.966664	-0.72	1.0e-01	Click!
Klf13	chr7_63936513_63936685	267	0.876987	-0.67	1.5e-01	Click!

Activity of the Klf13 motif across conditions

Conditions sorted by the z-value of the Klf13 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_139020930_139021245	2.06	Gm45613	predicted gene 45613	88	0.97
chr10_95720533_95720688	0.88	1110019B22Rik	RIKEN cDNA 1110019B22 gene	1879	0.2
chr7_66005228_66005393	0.66	Pcsk6	proprotein convertase subtilisin/kexin type 6	33108	0.12
chrY_90739212_90739561	0.60	Mid1-ps1	midline 1, pseudogene 1	13671	0.18
chr4_35134107_35134262	0.57	Ifnk	interferon kappa	17872	0.17
chr17_14175138_14175307	0.54	Gm34510	predicted gene, 34510	28506	0.14
chr11_67081331_67081503	0.48	Myh3	myosin, heavy polypeptide 3, skeletal muscle, embryonic	3117	0.17
chr11_97428221_97428386	0.46	Arhgap23	Rho GTPase activating protein 23	7982	0.16
chr8_71559035_71559219	0.45	Tmem221	transmembrane protein 221	256	0.79
chr6_90486122_90486491	0.44	Gm45901	predicted gene 45901	87	0.54
chr6_148212064_148212226	0.44	Ergic2	ERGIC and golgi 2	38	0.58
chr5_38560875_38561037	0.40	Wdr1	WD repeat domain 1	587	0.71
chr4_150874506_150874750	0.39	Errfi1	ERBB receptor feedback inhibitor 1	19555	0.12
chr17_29841749_29841925	0.39	Mdga1	MAM domain containing glycosylphosphatidylinositol anchor 1	584	0.73
chr10_117418076_117418301	0.37	Gm40770	predicted gene, 40770	4284	0.16
chr16_22919975_22920126	0.36	Fetub	fetuin beta	187	0.91
chr18_60603591_60603778	0.35	Synpo	synaptopodin	3187	0.2
chr6_116195979_116196139	0.34	Gm8213	predicted pseudogene 8213	201	0.89
chr3_105893960_105894139	0.34	Adora3	adenosine A3 receptor	10372	0.12
chr2_158176890_158177041	0.34	1700060C20Rik	RIKEN cDNA 1700060C20 gene	15043	0.14
chr1_191186557_191186730	0.33	Atf3	activating transcription factor 3	3303	0.18
chr7_80156693_80156942	0.33	Gm45202	predicted gene 45202	1648	0.25
chr4_133804499_133804683	0.32	Gm25270	predicted gene, 25270	6872	0.14
chr1_182585565_182585739	0.31	Capn8	calpain 8	20614	0.16
chr15_31338782_31338933	0.31	Ankrd33b	ankyrin repeat domain 33B	13608	0.15
chr2_85047886_85048056	0.30	Tnks1bp1	tankyrase 1 binding protein 1	51	0.96
chr4_47245499_47245708	0.30	Col15a1	collagen, type XV, alpha 1	12336	0.2
chr19_44997151_44997302	0.28	Sema4g	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G	5090	0.11
chr17_83503811_83503975	0.28	Cox7a2l	cytochrome c oxidase subunit 7A2 like	613	0.8
chr7_27178957_27179117	0.27	Rab4b	RAB4B, member RAS oncogene family	141	0.86
chr9_31211792_31211960	0.27	Aplp2	amyloid beta (A4) precursor-like protein 2	61	0.98
chr12_14152257_14152408	0.27	Lratd1	LRAT domain containing 1	278	0.93
chr10_80168459_80168625	0.26	Cirbp	cold inducible RNA binding protein	656	0.47
chr2_167014815_167015114	0.26	Ddx27	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	229	0.87
chr13_98689660_98689822	0.26	Tmem171	transmembrane protein 171	5027	0.15
chr11_69326130_69326304	0.26	Kcnab3	potassium voltage-gated channel, shaker-related subfamily, beta member 3	41	0.93
chr15_99113382_99113533	0.26	Spats2	spermatogenesis associated, serine-rich 2	12459	0.09
chrX_8252648_8252921	0.26	Ftsj1	FtsJ RNA methyltransferase homolog 1 (E. coli)	378	0.8
chr2_170155421_170155732	0.25	Zfp217	zinc finger protein 217	7473	0.29
chr1_39192284_39192607	0.25	Npas2	neuronal PAS domain protein 2	1286	0.45
chr8_94012059_94012219	0.25	Amfr	autocrine motility factor receptor	12	0.97
chr5_129895249_129895421	0.25	Zbed5	zinc finger, BED type containing 5	388	0.71
chr11_117836449_117836615	0.24	Afmid	arylformamidase	4259	0.1
chr5_115732580_115732733	0.24	Bicdl1	BICD family like cargo adaptor 1	1035	0.52
chr9_94155767_94155925	0.24	Gm5369	predicted gene 5369	16384	0.29
chr3_142709083_142709286	0.24	Kyat3	kynurenine aminotransferase 3	8090	0.14
chr7_19665320_19665478	0.23	Clptm1	cleft lip and palate associated transmembrane protein 1	366	0.7
chr10_79908555_79908720	0.23	Med16	mediator complex subunit 16	181	0.71
chr15_78340778_78340947	0.22	Mir7676-2	microRNA 7676-2	7737	0.12
chr7_16874839_16875265	0.22	9330104G04Rik	RIKEN cDNA 9330104G04 gene	166	0.6
chr1_35931118_35931293	0.22	Gm8022	predicted gene 8022	27714	0.14
chr5_74704572_74704742	0.22	Gm15984	predicted gene 15984	1637	0.29
chr9_107289789_107289967	0.22	Mapkapk3	mitogen-activated protein kinase-activated protein kinase 3	1	0.95
chr5_114826323_114826479	0.22	Ywhaq-ps2	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta, pseudogene 2	2814	0.12
chr17_31519992_31520147	0.21	Ndufv3	NADH:ubiquinone oxidoreductase core subunit V3	46	0.53
chr3_39220041_39220211	0.21	Gm43008	predicted gene 43008	2280	0.42
chr7_27447795_27447954	0.21	Blvrb	biliverdin reductase B (flavin reductase (NADPH))	104	0.61
chr17_84879283_84879445	0.21	Gm49982	predicted gene, 49982	23205	0.14
chr12_21145146_21145377	0.20	Asap2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	33307	0.16
chr6_4086907_4087076	0.20	Bet1	Bet1 golgi vesicular membrane trafficking protein	19	0.98
chr2_38519062_38519254	0.20	Nek6	NIMA (never in mitosis gene a)-related expressed kinase 6	4532	0.14
chr2_152707734_152707946	0.20	H13	histocompatibility 13	16001	0.09
chr19_4300270_4300606	0.20	Grk2	G protein-coupled receptor kinase 2	4770	0.1
chr15_67039473_67039636	0.20	Gm31342	predicted gene, 31342	504	0.83
chr1_188858745_188858917	0.19	Ush2a	usherin	94913	0.08
chr9_120582294_120582487	0.19	Gm47062	predicted gene, 47062	2255	0.19
chr2_73892795_73892960	0.19	Atf2	activating transcription factor 2	238	0.93
chr6_140874934_140875096	0.19	Gm30524	predicted gene, 30524	80594	0.09
chr1_118627791_118627969	0.19	Tfcp2l1	transcription factor CP2-like 1	65	0.97
chr10_95193833_95194034	0.18	Gm48874	predicted gene, 48874	33572	0.14
chr6_82652519_82652678	0.18	Pole4	polymerase (DNA-directed), epsilon 4 (p12 subunit)	78	0.97
chr8_71272393_71272552	0.18	Haus8	4HAUS augmin-like complex, subunit 8	6	0.77
chr17_35909704_35909977	0.18	Atat1	alpha tubulin acetyltransferase 1	101	0.88
chrY_90740044_90740606	0.18	Mid1-ps1	midline 1, pseudogene 1	12732	0.18
chr16_96127966_96128133	0.18	Hmgn1	high mobility group nucleosomal binding domain 1	320	0.83
chr4_119223756_119224101	0.18	Gm12898	predicted gene 12898	754	0.42
chr1_165763620_165763778	0.18	Creg1	cellular repressor of E1A-stimulated genes 1	47	0.95
chr18_12941778_12941952	0.17	Osbpl1a	oxysterol binding protein-like 1A	24	0.98
chr14_51884664_51884952	0.17	Mettl17	methyltransferase like 17	34	0.94
chr17_55956278_55956439	0.17	Yju2	YJU2 splicing factor	2741	0.11
chr2_34897940_34898106	0.17	Phf19	PHD finger protein 19	6129	0.11
chr3_9038418_9038576	0.17	Gm37616	predicted gene, 37616	8995	0.17
chr4_123686928_123687079	0.17	Macf1	microtubule-actin crosslinking factor 1	2643	0.2
chr4_43442956_43443142	0.17	Tesk1	testis specific protein kinase 1	272	0.82
chr15_88837187_88837359	0.17	Gm23144	predicted gene, 23144	1973	0.24
chr15_12248377_12248536	0.17	Mtmr12	myotubularin related protein 12	25102	0.12
chr5_113219993_113220303	0.17	2900026A02Rik	RIKEN cDNA 2900026A02 gene	1088	0.42
chr1_136008248_136008409	0.17	Tmem9	transmembrane protein 9	178	0.92
chr1_42474261_42474413	0.17	Gm37047	predicted gene, 37047	17476	0.25
chr9_44327277_44327612	0.16	Dpagt1	dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)	539	0.46
chr15_67110643_67110805	0.16	St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	3268	0.32
chr4_134796652_134796803	0.16	Maco1	macoilin 1	14486	0.18
chr2_163308491_163308647	0.16	Tox2	TOX high mobility group box family member 2	11809	0.2
chr8_84707765_84707923	0.16	Nfix	nuclear factor I/X	128	0.92
chr4_43040334_43040495	0.16	Fam214b	family with sequence similarity 214, member B	119	0.93
chr7_45714696_45714867	0.16	Sphk2	sphingosine kinase 2	426	0.47
chr16_30512503_30512806	0.16	Tmem44	transmembrane protein 44	28255	0.16
chr12_100958810_100958969	0.15	Ccdc88c	coiled-coil domain containing 88C	13716	0.12
chr19_5118250_5118577	0.15	Klc2	kinesin light chain 2	113	0.76
chr11_59787617_59787784	0.15	Pld6	phospholipase D family, member 6	55	0.95
chr1_184732600_184732772	0.15	Hlx	H2.0-like homeobox	67	0.96
chr12_52314917_52315090	0.15	Gm47431	predicted gene, 47431	133122	0.04
chr14_47189631_47189815	0.15	Gch1	GTP cyclohydrolase 1	310	0.8
chr15_62203372_62203523	0.15	Pvt1	Pvt1 oncogene	14776	0.23
chrX_150813018_150813184	0.14	Maged2	melanoma antigen, family D, 2	23	0.97
chr9_21265122_21265283	0.14	Atg4d	autophagy related 4D, cysteine peptidase	91	0.93
chr10_24830554_24830712	0.14	Enpp3	ectonucleotide pyrophosphatase/phosphodiesterase 3	1173	0.49
chr13_49216001_49216172	0.14	Card19	caspase recruitment domain family, member 19	49	0.97
chr7_19811188_19811394	0.14	Bcl3	B cell leukemia/lymphoma 3	598	0.46
chr11_119238465_119238619	0.14	Ccdc40	coiled-coil domain containing 40	176	0.92
chr2_167538011_167538171	0.14	Snai1	snail family zinc finger 1	104	0.94
chr17_47438043_47438256	0.14	1700001C19Rik	RIKEN cDNA 1700001C19 gene	773	0.44
chr17_87282754_87282914	0.14	4833418N02Rik	RIKEN cDNA 4833418N02 gene	20	0.52
chr5_138280001_138280359	0.14	Stag3	stromal antigen 3	60	0.52
chr7_25619112_25619443	0.14	Dmac2	distal membrane arm assembly complex 2	137	0.9
chr4_156197972_156198140	0.14	Agrn	agrin	568	0.56
chr10_61492177_61492335	0.14	Gm47595	predicted gene, 47595	4034	0.12
chr8_72239914_72240076	0.13	Ap1m1	adaptor-related protein complex AP-1, mu subunit 1	23	0.95
chr9_119100530_119100792	0.13	Dlec1	deleted in lung and esophageal cancer 1	1817	0.25
chr11_5445001_5445157	0.13	Znrf3	zinc and ring finger 3	232	0.93
chr8_125199868_125200019	0.13	Gm16237	predicted gene 16237	27380	0.22
chr7_16313428_16313735	0.13	Bbc3	BCL2 binding component 3	64	0.96
chr11_67025097_67025255	0.13	Tmem220	transmembrane protein 220	22	0.97
chr14_30916422_30916581	0.13	Itih3	inter-alpha trypsin inhibitor, heavy chain 3	1114	0.35
chr10_40257637_40257797	0.13	Gtf3c6	general transcription factor IIIC, polypeptide 6, alpha	41	0.92
chr12_4874314_4874496	0.12	Mfsd2b	major facilitator superfamily domain containing 2B	46	0.96
chr4_152108046_152108214	0.12	Plekhg5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5	401	0.76
chr2_172826555_172826706	0.12	Gm22773	predicted gene, 22773	37711	0.18
chr8_57488604_57488764	0.12	2500002B13Rik	RIKEN cDNA 2500002B13 gene	630	0.45
chr8_94876193_94876353	0.12	Dok4	docking protein 4	57	0.95
chr11_75247267_75247439	0.12	Rtn4rl1	reticulon 4 receptor-like 1	53570	0.07
chr19_29325385_29325550	0.12	Insl6	insulin-like 6	111	0.95
chr7_19228690_19228852	0.12	Opa3	optic atrophy 3	388	0.68
chr7_19118353_19118670	0.12	Gm4969	predicted gene 4969	143	0.87
chr11_23254748_23254899	0.12	Xpo1	exportin 1	1218	0.51
chr10_76531437_76531608	0.12	Lss	lanosterol synthase	66	0.96
chr8_94183220_94183416	0.12	Gm39228	predicted gene, 39228	29	0.95
chr12_8921530_8921697	0.12	Laptm4a	lysosomal-associated protein transmembrane 4A	51	0.97
chr7_44858030_44858203	0.12	Pnkp	polynucleotide kinase 3'- phosphatase	380	0.64
chr9_44515546_44515772	0.11	Cxcr5	chemokine (C-X-C motif) receptor 5	10762	0.07
chr15_9072830_9073005	0.11	Nadk2	NAD kinase 2, mitochondrial	1230	0.52
chr3_145556330_145556492	0.11	Col24a1	collagen, type XXIV, alpha 1	11438	0.2
chr8_36377048_36377257	0.11	Gm5787	predicted gene 5787	3519	0.25
chr17_65951168_65951335	0.11	Twsg1	twisted gastrulation BMP signaling modulator 1	25	0.97
chr13_94177289_94177442	0.11	Lhfpl2	lipoma HMGIC fusion partner-like 2	3373	0.25
chr2_32751402_32751562	0.11	Tor2a	torsin family 2, member A	5752	0.08
chr11_75047480_75047670	0.11	Gm12333	predicted gene 12333	8227	0.13
chr11_113684528_113684688	0.11	D11Wsu47e	DNA segment, Chr 11, Wayne State University 47, expressed	161	0.77
chr13_13954579_13954776	0.11	B3galnt2	UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2	3	0.96
chr8_64946983_64947186	0.11	Tmem192	transmembrane protein 192	101	0.88
chr2_35336999_35337164	0.11	Stom	stomatin	105	0.95
chr14_46832037_46832198	0.11	Cgrrf1	cell growth regulator with ring finger domain 1	8	0.56
chr17_56627213_56627375	0.11	Lonp1	lon peptidase 1, mitochondrial	407	0.62
chr15_10675955_10676106	0.11	Rai14	retinoic acid induced 14	37510	0.14
chr9_18473377_18473557	0.11	Zfp558	zinc finger protein 558	45	0.96
chr8_95293260_95293422	0.11	Cngb1	cyclic nucleotide gated channel beta 1	328	0.85
chr9_21918187_21918359	0.11	Rab3d	RAB3D, member RAS oncogene family	81	0.93
chrX_73967268_73967441	0.11	Hcfc1	host cell factor C1	997	0.39
chr10_21420912_21421063	0.11	1700021A07Rik	RIKEN cDNA 1700021A07 gene	1510	0.3
chr10_59951771_59951950	0.10	Ddit4	DNA-damage-inducible transcript 4	26	0.98
chr14_122105762_122105950	0.10	A330035P11Rik	RIKEN cDNA A330035P11 gene	1097	0.31
chr4_155469018_155469192	0.10	Tmem52	transmembrane protein 52	9	0.96
chr14_63164949_63165115	0.10	Fdft1	farnesyl diphosphate farnesyl transferase 1	107	0.96
chr16_22899718_22899927	0.10	Ahsg	alpha-2-HS-glycoprotein	4958	0.13
chr10_80577406_80577585	0.10	Klf16	Kruppel-like factor 16	174	0.87
chr11_51856076_51856454	0.10	Jade2	jade family PHD finger 2	860	0.59
chr3_90509502_90509661	0.10	Chtop	chromatin target of PRMT1	83	0.92
chr13_95894500_95894710	0.10	Iqgap2	IQ motif containing GTPase activating protein 2	2122	0.3
chr15_79774430_79774597	0.10	Dnal4	dynein, axonemal, light chain 4	46	0.95
chr16_57167289_57167444	0.10	Nit2	nitrilase family, member 2	25	0.5
chr1_74721665_74721828	0.10	Cyp27a1	cytochrome P450, family 27, subfamily a, polypeptide 1	8172	0.13
chr7_115948051_115948232	0.10	Sox6	SRY (sex determining region Y)-box 6	46945	0.13
chr17_56079134_56079310	0.09	Hdgfl2	HDGF like 2	412	0.69
chr4_132329477_132329639	0.09	Trnau1ap	tRNA selenocysteine 1 associated protein 1	20	0.92
chr8_83608021_83608180	0.09	Dnajb1	DnaJ heat shock protein family (Hsp40) member B1	93	0.54
chr9_57295766_57295926	0.09	1700017B05Rik	RIKEN cDNA 1700017B05 gene	33234	0.11
chr12_21286198_21286361	0.09	Itgb1bp1	integrin beta 1 binding protein 1	5	0.55
chr1_105990177_105990357	0.09	Gm7160	predicted gene 7160	15	0.64
chr4_104975117_104975442	0.09	Gm12721	predicted gene 12721	5150	0.27
chr11_59191846_59192317	0.09	Guk1	guanylate kinase 1	129	0.91
chr2_11535513_11535687	0.09	Gm37975	predicted gene, 37975	906	0.49
chr10_119614856_119615049	0.09	Gm47027	predicted gene, 47027	2768	0.28
chr10_81320325_81320502	0.09	Cactin	cactin, spliceosome C complex subunit	690	0.37
chr7_29170009_29170256	0.09	Ggn	gametogenetin	78	0.73
chr3_108467871_108468033	0.09	5330417C22Rik	RIKEN cDNA 5330417C22 gene	2129	0.16
chr5_144358410_144358608	0.09	Dmrt1i	Dmrt1 interacting ncRNA	16	0.87
chr8_125133982_125134146	0.09	Disc1	disrupted in schizophrenia 1	46077	0.14
chr8_126516634_126516823	0.09	Gm6091	predicted pseudogene 6091	40316	0.14
chr11_16803990_16804532	0.09	Egfros	epidermal growth factor receptor, opposite strand	26441	0.18
chr6_90395849_90396012	0.09	C030015A19Rik	RIKEN cDNA C030015A19 gene	9123	0.12
chr12_86825129_86825313	0.09	Gm10095	predicted gene 10095	21246	0.17
chr17_25474786_25474993	0.09	Tekt4	tektin 4	585	0.6
chr7_30626129_30626287	0.09	Cox6b1	cytochrome c oxidase, subunit 6B1	57	0.91
chr17_84875170_84875325	0.09	Gm9400	predicted gene 9400	22709	0.14
chr17_80004938_80005095	0.09	Gm41625	predicted gene, 41625	23354	0.13
chr1_195092267_195092425	0.09	Cd46	CD46 antigen, complement regulatory protein	97	0.95
chr7_99828286_99828448	0.09	Neu3	neuraminidase 3	50	0.96
chr4_133085038_133085232	0.09	Ahdc1	AT hook, DNA binding motif, containing 1	18886	0.17
chr14_31641238_31641408	0.09	Hacl1	2-hydroxyacyl-CoA lyase 1	37	0.72
chr9_26923072_26923237	0.08	Gm1110	predicted gene 1110	43	0.97

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf13

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.1	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0	0.1	GO:0042167	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.1	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	0.2	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.2	GO:0044351	macropinocytosis(GO:0044351)
0.0	0.2	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.0	0.1	GO:0051697	protein delipidation(GO:0051697)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.2	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0	0.1	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
0.0	0.3	GO:0030836	positive regulation of actin filament depolymerization(GO:0030836)
0.0	0.1	GO:0034436	glycoprotein transport(GO:0034436)
0.0	0.1	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0	0.1	GO:0043382	positive regulation of memory T cell differentiation(GO:0043382)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.2	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.0	0.1	GO:0072061	inner medullary collecting duct development(GO:0072061)
0.0	0.1	GO:1903121	regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121)
0.0	0.1	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.2	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.1	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.0	0.2	GO:0032906	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0	0.1	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0002071	glandular epithelial cell maturation(GO:0002071)
0.0	0.3	GO:0002082	regulation of oxidative phosphorylation(GO:0002082)
0.0	0.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.1	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.0	0.3	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.2	GO:0035646	endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0	0.1	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0007066	female meiosis sister chromatid cohesion(GO:0007066)
0.0	0.1	GO:1903273	regulation of sodium ion export(GO:1903273) regulation of sodium ion export from cell(GO:1903276)
0.0	0.1	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.1	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.0	0.0	GO:2000409	positive regulation of T cell extravasation(GO:2000409)
0.0	0.2	GO:0002070	epithelial cell maturation(GO:0002070)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.1	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0	0.0	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.1	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.1	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.0	GO:0019042	viral latency(GO:0019042)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.0	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.0	0.0	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.0	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.0	0.2	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.0	GO:0006848	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0	0.0	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.0	0.1	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.0	0.1	GO:0045820	negative regulation of glycolytic process(GO:0045820)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.0	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.1	GO:0072015	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0	0.4	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0044539	long-chain fatty acid import(GO:0044539)
0.0	0.1	GO:0009437	carnitine metabolic process(GO:0009437)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0000836	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1	0.2	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.2	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.0	0.1	GO:1990393	3M complex(GO:1990393)
0.0	0.1	GO:0000802	transverse filament(GO:0000802)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.1	GO:0002079	inner acrosomal membrane(GO:0002079)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.2	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.1	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.0	GO:0033647	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0	0.0	GO:0097543	ciliary inversin compartment(GO:0097543)
0.0	0.0	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.0	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0019145	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.1	0.2	GO:1904288	BAT3 complex binding(GO:1904288)
0.0	0.1	GO:0008808	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0	0.2	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0	0.1	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.1	GO:0003933	GTP cyclohydrolase activity(GO:0003933)
0.0	0.1	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0052796	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	0.2	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.3	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.0	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	0.1	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.0	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.1	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.0	0.2	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.1	GO:0031559	oxidosqualene cyclase activity(GO:0031559)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.0	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.0	GO:0089720	death effector domain binding(GO:0035877) caspase binding(GO:0089720)
0.0	0.0	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.0	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.0	GO:0016018	cyclosporin A binding(GO:0016018)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.3	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	REACTOME FRS2 MEDIATED CASCADE	Genes involved in FRS2-mediated cascade
0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins