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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Klf3

Z-value: 1.32

Motif logo

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Transcription factors associated with Klf3

Gene Symbol Gene ID Gene Info
Klf3
ENSMUSG00000029178.8 Kruppel-like factor 3 (basic)

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr5_64811771_64811965Klf34710.766893-0.984.1e-04Click!
chr5_64840100_64840327Klf3134040.1512700.971.2e-03Click!
chr5_64795807_64795970Klf375000.1534580.862.7e-02Click!
chr5_64812184_64812344Klf3750.9647280.863.0e-02Click!
chr5_64809339_64809781Klf327790.2068980.834.2e-02Click!

Activity of the Klf3 motif across conditions

Conditions sorted by the z-value of the Klf3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_8778168_8778353 0.90 Sdc1
 syndecan 1
 6457
 0.19
chr13_100577098_100577269 0.87 Gm8847
 predicted gene 8847
 17151
 0.1
chr8_104101509_104101690 0.82 Cdh5
 cadherin 5
 26
 0.97
chr8_121591389_121591573 0.82 Map1lc3b
 microtubule-associated protein 1 light chain 3 beta
 769
 0.5
chr13_9431614_9431799 0.81 Gm48871
 predicted gene, 48871
 14194
 0.17
chr18_56437222_56437386 0.79 Gramd3
 GRAM domain containing 3
 5172
 0.22
chr12_69299371_69299530 0.78 Klhdc2
 kelch domain containing 2
 2695
 0.15
chr6_48595408_48595586 0.77 Repin1
 replication initiator 1
 1178
 0.2
chr15_31344240_31344565 0.77 Ankrd33b
 ankyrin repeat domain 33B
 19153
 0.14
chr10_82623685_82624011 0.76 1190007I07Rik
 RIKEN cDNA 1190007I07 gene
 620
 0.65
chr10_68355501_68355861 0.75 4930545H06Rik
 RIKEN cDNA 4930545H06 gene
 34539
 0.17
chr11_98770256_98770457 0.75 Nr1d1
 nuclear receptor subfamily 1, group D, member 1
 70
 0.94
chr16_20674169_20674320 0.73 Eif4g1
 eukaryotic translation initiation factor 4, gamma 1
 133
 0.89
chr3_105893960_105894139 0.72 Adora3
 adenosine A3 receptor
 10372
 0.12
chr12_21227287_21227746 0.70 AC156032.1
19807
 0.14
chr1_165617606_165617906 0.67 Mpzl1
 myelin protein zero-like 1
 3777
 0.14
chr12_12320785_12320940 0.66 Fam49a
 family with sequence similarity 49, member A
 58673
 0.14
chr12_73300604_73300762 0.66 Slc38a6
 solute carrier family 38, member 6
 13623
 0.17
chr1_133296542_133296715 0.63 Plekha6
 pleckstrin homology domain containing, family A member 6
 1323
 0.33
chr17_78249106_78249271 0.62 Crim1
 cysteine rich transmembrane BMP regulator 1 (chordin like)
 11416
 0.18
chr3_22076000_22076172 0.60 Gm43672
 predicted gene 43672
 56
 0.91
chr10_80647071_80647222 0.60 Btbd2
 BTB (POZ) domain containing 2
 564
 0.54
chr9_44398704_44398895 0.60 Slc37a4
 solute carrier family 37 (glucose-6-phosphate transporter), member 4
 325
 0.63
chr3_81102286_81102462 0.59 Gm16000
 predicted gene 16000
 61937
 0.11
chr4_128804978_128805273 0.57 Zfp362
 zinc finger protein 362
 920
 0.55
chr1_180279676_180280012 0.57 Psen2
 presenilin 2
 16406
 0.13
chr4_140787577_140787739 0.57 Padi4
 peptidyl arginine deiminase, type IV
 13422
 0.12
chr9_44551273_44551431 0.57 Cxcr5
 chemokine (C-X-C motif) receptor 5
 4934
 0.09
chr11_69073830_69074123 0.55 Gm12306
 predicted gene 12306
 514
 0.33
chr10_51455905_51456056 0.55 Gm46189
 predicted gene, 46189
 0
 0.97
chr13_111957222_111957419 0.54 Gm15322
 predicted gene 15322
 34146
 0.14
chr1_164788357_164788561 0.54 Dpt
 dermatopontin
 8185
 0.18
chr6_3346058_3346227 0.52 Gm20559
 predicted gene, 20559
 14
 0.96
chr17_36019112_36019264 0.52 H2-T24
 histocompatibility 2, T region locus 24
 1337
 0.17
chr3_121276958_121277317 0.51 Gm30517
 predicted gene, 30517
 387
 0.81
chr6_3399444_3399625 0.51 Samd9l
 sterile alpha motif domain containing 9-like
 38
 0.97
chr3_89887959_89888297 0.49 Gm42809
 predicted gene 42809
 24788
 0.1
chr4_35098657_35098808 0.49 Ifnk
 interferon kappa
 53324
 0.12
chr8_116993108_116993270 0.47 Gcsh
 glycine cleavage system protein H (aminomethyl carrier)
 348
 0.84
chr13_3260533_3260700 0.47 Gm40653
 predicted gene, 40653
 12619
 0.17
chr1_134406120_134406612 0.47 Cyb5r1
 cytochrome b5 reductase 1
 53
 0.95
chr7_46839028_46839384 0.47 Ldha
 lactate dehydrogenase A
 2269
 0.15
chr5_139382284_139382462 0.47 Gpr146
 G protein-coupled receptor 146
 1792
 0.22
chr19_23150997_23151148 0.46 Mir1192
 microRNA 1192
 1641
 0.33
chr5_105698740_105698909 0.46 Lrrc8d
 leucine rich repeat containing 8D
 1145
 0.57
chr11_78550155_78550328 0.45 Tmem97
 transmembrane protein 97
 536
 0.54
chr1_66895610_66896410 0.45 Gm25832
 predicted gene, 25832
 29213
 0.09
chr7_35119039_35119269 0.44 Cebpa
 CCAAT/enhancer binding protein (C/EBP), alpha
 139
 0.78
chr4_139978986_139979192 0.43 Klhdc7a
 kelch domain containing 7A
 11063
 0.16
chr17_24443544_24443715 0.43 Dnase1l2
 deoxyribonuclease 1-like 2
 524
 0.46
chr7_44819003_44819183 0.43 Nup62
 nucleoporin 62
 656
 0.42
chr10_116297940_116298100 0.42 Ptprb
 protein tyrosine phosphatase, receptor type, B
 3352
 0.23
chr4_155162532_155162683 0.42 Ski
 ski sarcoma viral oncogene homolog (avian)
 25689
 0.14
chr13_111861024_111861186 0.41 Gm15324
 predicted gene 15324
 4109
 0.15
chr16_94546158_94546496 0.41 Vps26c
 VPS26 endosomal protein sorting factor C
 19497
 0.16
chr6_124694855_124695031 0.40 Lpcat3
 lysophosphatidylcholine acyltransferase 3
 6476
 0.07
chr4_98508428_98508827 0.40 Patj
 PATJ, crumbs cell polarity complex component
 10344
 0.22
chr9_43231970_43232132 0.40 Oaf
 out at first homolog
 6959
 0.15
chr2_29426777_29426974 0.40 Gm13402
 predicted gene 13402
 30416
 0.13
chr1_88765371_88765522 0.39 Platr5
 pluripotency associated transcript 5
 10492
 0.2
chr15_75892571_75892918 0.38 Naprt
 nicotinate phosphoribosyltransferase
 176
 0.87
chr17_34722831_34722982 0.38 Cyp21a2-ps
 cytochrome P450, family 21, subfamily a, polypeptide 2 pseudogene
 654
 0.44
chr7_105770059_105770232 0.38 Gm15645
 predicted gene 15645
 7824
 0.09
chr3_32495485_32495636 0.38 Kcnmb3
 potassium large conductance calcium-activated channel, subfamily M, beta member 3
 3329
 0.17
chr7_144014599_144014780 0.38 Mir3105
 microRNA 3105
 5435
 0.21
chr18_60619666_60619817 0.37 Synpo
 synaptopodin
 3584
 0.21
chr3_9947781_9947953 0.37 Gm17877
 predicted gene, 17877
 24134
 0.16
chr3_106545726_106545888 0.36 Cept1
 choline/ethanolaminephosphotransferase 1
 1775
 0.22
chr9_106452941_106453115 0.35 Gm28959
 predicted gene 28959
 110
 0.68
chr11_20396557_20396740 0.35 Gm12034
 predicted gene 12034
 49764
 0.12
chr2_84650666_84651104 0.35 Ctnnd1
 catenin (cadherin associated protein), delta 1
 120
 0.92
chr10_93488942_93489116 0.35 Hal
 histidine ammonia lyase
 226
 0.91
chr13_34742265_34742434 0.34 Fam50b
 family with sequence similarity 50, member B
 2737
 0.19
chr7_45132163_45132314 0.33 Flt3l
 FMS-like tyrosine kinase 3 ligand
 369
 0.53
chr12_100527851_100528010 0.33 Ttc7b
 tetratricopeptide repeat domain 7B
 7104
 0.18
chr5_142440544_142440746 0.33 Ap5z1
 adaptor-related protein complex 5, zeta 1 subunit
 23299
 0.17
chr15_67102477_67102648 0.33 St3gal1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 11430
 0.24
chr15_75270297_75270448 0.33 Ly6f
 lymphocyte antigen 6 complex, locus F
 1670
 0.23
chr7_141096744_141096936 0.32 Sigirr
 single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
 101
 0.92
chr13_112751580_112751773 0.32 Gm47850
 predicted gene, 47850
 13172
 0.14
chr5_124007295_124007675 0.32 Gm37939
 predicted gene, 37939
 2837
 0.13
chr5_64806228_64806550 0.32 Gm20033
 predicted gene, 20033
 2272
 0.21
chr1_181228977_181229128 0.32 A430110L20Rik
 RIKEN cDNA A430110L20 gene
 2976
 0.19
chr7_80232137_80232317 0.32 Cib1
 calcium and integrin binding 1 (calmyrin)
 268
 0.69
chr12_21136203_21136399 0.31 Asap2
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
 24347
 0.18
chr18_64265864_64266047 0.31 St8sia3
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
 31
 0.97
chr15_102177432_102177780 0.31 Csad
 cysteine sulfinic acid decarboxylase
 1413
 0.26
chr8_84984897_84985063 0.31 Hook2
 hook microtubule tethering protein 2
 5623
 0.06
chr11_120005928_120006087 0.31 Aatk
 apoptosis-associated tyrosine kinase
 6401
 0.11
chr15_100674641_100674912 0.31 Cela1
 chymotrypsin-like elastase family, member 1
 4086
 0.11
chr10_80033033_80033205 0.31 Polr2e
 polymerase (RNA) II (DNA directed) polypeptide E
 4066
 0.1
chr10_61328072_61328223 0.30 Pald1
 phosphatase domain containing, paladin 1
 14180
 0.12
chr8_106138653_106138804 0.30 1810019D21Rik
 RIKEN cDNA 1810019D21 gene
 1663
 0.21
chr16_80273340_80273491 0.30 Gm23083
 predicted gene, 23083
 136063
 0.05
chr8_104375548_104375738 0.30 Gm45877
 predicted gene 45877
 11975
 0.09
chr13_41253417_41253699 0.30 Smim13
 small integral membrane protein 13
 3714
 0.15
chr17_73826207_73826394 0.30 Ehd3
 EH-domain containing 3
 21459
 0.18
chr2_158121562_158121714 0.29 Gm20412
 predicted gene 20412
 4484
 0.17
chr1_133863573_133863878 0.29 Gm28441
 predicted gene 28441
 28536
 0.11
chr11_55126402_55126555 0.29 Mup-ps22
 major urinary protein, pseudogene 22
 2783
 0.16
chr6_35494062_35494219 0.29 Gm23053
 predicted gene, 23053
 30498
 0.19
chr11_86985069_86985237 0.29 Ypel2
 yippee like 2
 8554
 0.17
chr16_94537265_94537456 0.29 Vps26c
 VPS26 endosomal protein sorting factor C
 10530
 0.18
chr1_160791931_160792321 0.29 Rabgap1l
 RAB GTPase activating protein 1-like
 812
 0.5
chr12_82915523_82915797 0.29 1700085C21Rik
 RIKEN cDNA 1700085C21 gene
 23495
 0.21
chr11_100935486_100935649 0.29 Stat3
 signal transducer and activator of transcription 3
 3813
 0.17
chr11_100623827_100624107 0.28 Nkiras2
 NFKB inhibitor interacting Ras-like protein 2
 956
 0.37
chr7_98500649_98500827 0.28 Gm23040
 predicted gene, 23040
 6216
 0.13
chr1_88954676_88954892 0.28 Gm4753
 predicted gene 4753
 22465
 0.19
chr7_28969946_28970152 0.28 Eif3k
 eukaryotic translation initiation factor 3, subunit K
 4787
 0.11
chr15_85675723_85675883 0.28 Lncppara
 long noncoding RNA near Ppara
 22187
 0.12
chr13_64153328_64153492 0.28 Zfp367
 zinc finger protein 367
 208
 0.83
chr8_34442687_34442913 0.28 Gm45349
 predicted gene 45349
 30195
 0.14
chr1_87764802_87764962 0.28 Atg16l1
 autophagy related 16-like 1 (S. cerevisiae)
 2019
 0.23
chr1_105354986_105355137 0.28 Gm17634
 predicted gene, 17634
 946
 0.48
chr17_46004571_46004735 0.27 Vegfa
 vascular endothelial growth factor A
 16719
 0.16
chr3_88146112_88146278 0.27 Mef2d
 myocyte enhancer factor 2D
 3621
 0.13
chr8_23192641_23192801 0.27 Gpat4
 glycerol-3-phosphate acyltransferase 4
 1783
 0.23
chr1_88654880_88655031 0.27 Gm29336
 predicted gene 29336
 1353
 0.35
chr11_120507725_120507906 0.27 Slc25a10
 solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
 10090
 0.06
chr11_98750923_98751087 0.27 Thra
 thyroid hormone receptor alpha
 2581
 0.15
chr9_70933007_70933160 0.27 Lipc
 lipase, hepatic
 1530
 0.39
chr4_102505805_102505983 0.27 Pde4b
 phosphodiesterase 4B, cAMP specific
 35497
 0.23
chr2_28525746_28525944 0.26 Ralgds
 ral guanine nucleotide dissociation stimulator
 2005
 0.19
chr5_145873496_145873886 0.26 Cyp3a11
 cytochrome P450, family 3, subfamily a, polypeptide 11
 3000
 0.22
chr2_179292597_179292961 0.26 Gm14293
 predicted gene 14293
 52289
 0.14
chr18_46631846_46631997 0.26 Gm3734
 predicted gene 3734
 1114
 0.44
chr17_29050362_29051086 0.26 Gm41556
 predicted gene, 41556
 2612
 0.13
chr7_143501066_143501235 0.26 Phlda2
 pleckstrin homology like domain, family A, member 2
 1391
 0.29
chr14_66636173_66636515 0.26 Adra1a
 adrenergic receptor, alpha 1a
 788
 0.71
chr1_120075577_120075750 0.26 Tmem37
 transmembrane protein 37
 1589
 0.37
chr19_5100696_5100847 0.26 Cnih2
 cornichon family AMPA receptor auxiliary protein 2
 2250
 0.11
chr1_132384418_132384569 0.26 Gm15849
 predicted gene 15849
 3364
 0.17
chr9_32833494_32833645 0.26 Gm37167
 predicted gene, 37167
 6353
 0.22
chr5_99994836_99995114 0.26 Gm17092
 predicted gene 17092
 15914
 0.13
chr6_128650063_128650348 0.25 Gm44420
 predicted gene, 44420
 1140
 0.26
chr10_93519889_93520065 0.25 Hal
 histidine ammonia lyase
 18852
 0.12
chrX_120050578_120050737 0.25 Gm16420
 predicted gene 16420
 64317
 0.12
chr4_144981227_144981590 0.25 Vps13d
 vacuolar protein sorting 13D
 2553
 0.3
chr7_4150769_4150950 0.25 Leng9
 leukocyte receptor cluster (LRC) member 9
 485
 0.61
chr18_38521952_38522103 0.25 Gm50349
 predicted gene, 50349
 40724
 0.12
chr1_4496427_4496626 0.25 Gm37587
 predicted gene, 37587
 25
 0.59
chr4_144901641_144901842 0.25 Dhrs3
 dehydrogenase/reductase (SDR family) member 3
 8522
 0.21
chr2_163468579_163468765 0.25 2310001K24Rik
 RIKEN cDNA 2310001K24 gene
 3285
 0.14
chr1_39869838_39870141 0.25 1700066B17Rik
 RIKEN cDNA 1700066B17 gene
 22655
 0.18
chr10_85193452_85193650 0.24 Cry1
 cryptochrome 1 (photolyase-like)
 8487
 0.2
chr1_89467714_89468048 0.24 Agap1
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
 12625
 0.19
chr2_152338389_152338546 0.24 Trib3
 tribbles pseudokinase 3
 5503
 0.1
chr14_54431415_54431610 0.24 Mmp14
 matrix metallopeptidase 14 (membrane-inserted)
 100
 0.92
chr9_33101315_33101483 0.24 Gm32171
 predicted gene, 32171
 49893
 0.13
chr14_7990964_7991352 0.24 Dnase1l3
 deoxyribonuclease 1-like 3
 3415
 0.22
chr12_52376859_52377022 0.24 Gm47431
 predicted gene, 47431
 71185
 0.11
chr6_28876568_28876734 0.24 Snd1
 staphylococcal nuclease and tudor domain containing 1
 3392
 0.27
chr3_89843106_89843448 0.24 She
 src homology 2 domain-containing transforming protein E
 5388
 0.14
chr1_36636614_36636765 0.23 Gm24133
 predicted gene, 24133
 27276
 0.09
chr7_141266376_141266537 0.23 Irf7
 interferon regulatory factor 7
 25
 0.94
chr5_121189338_121189507 0.23 Ptpn11
 protein tyrosine phosphatase, non-receptor type 11
 1907
 0.24
chr8_11340394_11340565 0.23 Col4a1
 collagen, type IV, alpha 1
 27653
 0.13
chr1_151346486_151346783 0.23 Gm10138
 predicted gene 10138
 1403
 0.31
chr12_113141120_113141303 0.23 Crip2
 cysteine rich protein 2
 639
 0.55
chr12_54313077_54313237 0.22 Gm47552
 predicted gene, 47552
 3858
 0.22
chr1_119290301_119290473 0.22 Gm29456
 predicted gene 29456
 36446
 0.14
chr15_81896525_81896724 0.22 Aco2
 aconitase 2, mitochondrial
 1318
 0.26
chr19_36629854_36630038 0.22 Hectd2os
 Hectd2, opposite strand
 3922
 0.26
chr14_121129398_121129725 0.22 Farp1
 FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
 27482
 0.23
chr8_89015607_89015979 0.22 Mir8110
 microRNA 8110
 8942
 0.24
chr6_91659872_91660034 0.22 Gm45217
 predicted gene 45217
 19270
 0.12
chr7_112187893_112188109 0.22 Dkk3
 dickkopf WNT signaling pathway inhibitor 3
 28944
 0.2
chr19_24017522_24017784 0.22 Gm50305
 predicted gene, 50305
 12873
 0.17
chr5_73103744_73103903 0.22 Fryl
 FRY like transcription coactivator
 5444
 0.18
chr3_38155310_38155488 0.22 Gm43821
 predicted gene 43821
 25208
 0.16
chr5_92822938_92823090 0.22 Shroom3
 shroom family member 3
 13544
 0.2
chr19_21106934_21107106 0.22 4930554I06Rik
 RIKEN cDNA 4930554I06 gene
 2310
 0.37
chr2_25095172_25095346 0.22 Noxa1
 NADPH oxidase activator 1
 110
 0.92
chr5_73647707_73647869 0.21 Sgcb
 sarcoglycan, beta (dystrophin-associated glycoprotein)
 2
 0.72
chr14_73374673_73374886 0.21 Itm2b
 integral membrane protein 2B
 1166
 0.51
chr10_77126560_77126749 0.21 Gm7775
 predicted gene 7775
 10446
 0.17
chr8_80880650_80880819 0.21 Gab1
 growth factor receptor bound protein 2-associated protein 1
 215
 0.85
chr9_108306051_108306209 0.21 Rhoa
 ras homolog family member A
 1
 0.5
chr11_50159467_50159635 0.21 Tbc1d9b
 TBC1 domain family, member 9B
 2112
 0.2
chr14_20082742_20082925 0.21 Saysd1
 SAYSVFN motif domain containing 1
 350
 0.87
chr1_170639090_170639313 0.21 Olfml2b
 olfactomedin-like 2B
 5331
 0.2
chrX_48343770_48343921 0.21 Bcorl1
 BCL6 co-repressor-like 1
 75
 0.97
chr7_27159930_27160235 0.20 Egln2
 egl-9 family hypoxia-inducible factor 2
 789
 0.36
chr18_38269268_38269419 0.20 Pcdh12
 protocadherin 12
 8616
 0.1
chr4_139577114_139577275 0.20 Iffo2
 intermediate filament family orphan 2
 2474
 0.23
chr12_21143230_21143533 0.20 Asap2
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
 31427
 0.16
chr11_60845341_60845511 0.20 Dhrs7b
 dehydrogenase/reductase (SDR family) member 7B
 14747
 0.09
chr4_150065927_150066095 0.20 Mir34a
 microRNA 34a
 2443
 0.16
chr8_35377910_35378565 0.20 Ppp1r3b
 protein phosphatase 1, regulatory subunit 3B
 1577
 0.3
chr4_144905236_144905418 0.20 Dhrs3
 dehydrogenase/reductase (SDR family) member 3
 12108
 0.2
chr2_118547575_118547732 0.20 Bmf
 BCL2 modifying factor
 54
 0.97
chr1_130661373_130661552 0.20 C4bp
 complement component 4 binding protein
 148
 0.93
chr17_36023597_36023890 0.19 H2-T24
 histocompatibility 2, T region locus 24
 3183
 0.08
chr7_127841086_127841237 0.19 Stx4a
 syntaxin 4A (placental)
 603
 0.48
chr6_72624193_72624362 0.19 Gm15401
 predicted gene 15401
 5011
 0.09
chr1_132329567_132329732 0.19 Nuak2
 NUAK family, SNF1-like kinase, 2
 2053
 0.21
chr19_3363639_3363796 0.19 Cpt1a
 carnitine palmitoyltransferase 1a, liver
 2613
 0.2
chr9_56949772_56949935 0.19 Snupn
 snurportin 1
 1025
 0.37
chr11_100523646_100523797 0.19 Acly
 ATP citrate lyase
 123
 0.93

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.4 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.8 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.1 0.3 GO:0097503 sialylation(GO:0097503)
0.1 0.3 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.4 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.4 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.4 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.1 0.2 GO:0097195 pilomotor reflex(GO:0097195)
0.1 0.2 GO:0090289 regulation of osteoclast proliferation(GO:0090289) positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.2 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.2 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:2000847 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0 0.1 GO:0030167 proteoglycan catabolic process(GO:0030167)
0.0 0.3 GO:0043173 nucleotide salvage(GO:0043173)
0.0 0.1 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101)
0.0 0.2 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.1 GO:0043366 beta selection(GO:0043366)
0.0 0.1 GO:0019448 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.2 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.1 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.0 0.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.1 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.4 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0043309 regulation of eosinophil degranulation(GO:0043309)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.2 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.1 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.1 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.2 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.0 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.2 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.0 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990)
0.0 0.0 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:0015817 histidine transport(GO:0015817)
0.0 0.0 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 0.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0060137 maternal process involved in parturition(GO:0060137)
0.0 0.0 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.2 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.1 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.1 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.0 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.0 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.0 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.0 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.1 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.1 GO:0046110 xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.0 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.0 GO:0015744 succinate transport(GO:0015744)
0.0 0.0 GO:0071926 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.0 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.0 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 0.1 GO:1903867 chorion development(GO:0060717) extraembryonic membrane development(GO:1903867)
0.0 0.6 GO:0001662 behavioral fear response(GO:0001662)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.0 GO:0070340 detection of bacterial lipopeptide(GO:0070340)
0.0 0.2 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.0 GO:0060336 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0 0.0 GO:0019249 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.0 0.0 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0 0.0 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
0.0 0.0 GO:0032345 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0 0.2 GO:2001273 glucose import in response to insulin stimulus(GO:0044381) regulation of glucose import in response to insulin stimulus(GO:2001273)
0.0 0.0 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.0 GO:0045472 response to ether(GO:0045472)
0.0 0.0 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.0 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.0 0.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.0 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.1 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.2 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.0 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.0 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.4 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 0.4 GO:0005915 zonula adherens(GO:0005915)
0.1 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0097651 phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.0 GO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.0 0.0 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.0 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 1.3 GO:0043296 apical junction complex(GO:0043296)
0.0 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.0 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.0 GO:0043293 apoptosome(GO:0043293)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.0 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.4 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 0.2 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.0 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.0 0.1 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004854 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0 0.1 GO:0032557 pyrimidine ribonucleotide binding(GO:0032557)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0018646 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.0 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.0 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0 0.0 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.9 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.0 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.0 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.1 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.0 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation