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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Lhx8

Z-value: 1.95

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Transcription factors associated with Lhx8

Gene Symbol	Gene ID	Gene Info
Lhx8 Ensembl NCBI MGI UniProt	ENSMUSG00000096225.2	LIM homeobox protein 8

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr3_154297576_154297741	Lhx8	27225	0.151037	-0.25	6.3e-01	Click!

Activity of the Lhx8 motif across conditions

Conditions sorted by the z-value of the Lhx8 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_74893395_74893777	2.28	Onecut1	one cut domain, family member 1	27102	0.13
chr7_63922331_63923024	1.48	Klf13	Kruppel-like factor 13	2193	0.22
chr1_67169083_67169234	1.44	Cps1	carbamoyl-phosphate synthetase 1	46132	0.15
chr7_72323573_72323742	1.35	Mctp2	multiple C2 domains, transmembrane 2	17049	0.28
chr8_93176962_93177159	1.33	Ces1d	carboxylesterase 1D	1771	0.27
chr1_107939897_107940125	1.32	D830032E09Rik	RIKEN cDNA D830032E09 gene	3302	0.23
chr2_42022364_42022535	1.30	Gm13461	predicted gene 13461	33620	0.23
chr11_16805061_16805227	1.27	Egfros	epidermal growth factor receptor, opposite strand	25558	0.18
chr2_81270139_81270299	1.25	Gm23900	predicted gene, 23900	273123	0.01
chr8_105095555_105095947	1.22	Ces3b	carboxylesterase 3B	7132	0.11
chr9_109966945_109967106	1.21	Map4	microtubule-associated protein 4	1992	0.21
chr11_16589661_16589834	1.18	Gm12663	predicted gene 12663	46319	0.12
chr1_21261382_21261702	1.15	Gsta3	glutathione S-transferase, alpha 3	8021	0.11
chr6_149344317_149344633	1.14	Gm15782	predicted gene 15782	9351	0.14
chr16_43408501_43408652	1.11	Gm15713	predicted gene 15713	11620	0.2
chr5_150362303_150362454	1.04	Fry	FRY microtubule binding protein	37275	0.13
chr5_87254769_87254962	1.03	Ugt2b37	UDP glucuronosyltransferase 2 family, polypeptide B37	61	0.96
chr19_20695080_20695252	1.02	Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7	32396	0.2
chr9_64383785_64383941	1.01	Megf11	multiple EGF-like-domains 11	1763	0.37
chr18_38370754_38370932	1.00	Gm4949	predicted gene 4949	10305	0.12
chr16_19655438_19655589	1.00	Gm49596	predicted gene, 49596	23611	0.13
chr8_114151087_114151399	0.98	Nudt7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	17601	0.25
chr8_114155044_114155305	0.98	Nudt7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	21532	0.24
chr9_94704515_94704673	0.98	Gm16262	predicted gene 16262	2275	0.28
chr5_100419251_100419681	0.95	Sec31a	Sec31 homolog A (S. cerevisiae)	3232	0.18
chr3_60408325_60408501	0.93	Mbnl1	muscleblind like splicing factor 1	64417	0.12
chr1_21264707_21265188	0.92	Gm28836	predicted gene 28836	6646	0.11
chr8_114147681_114147946	0.91	Nudt7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	14171	0.26
chr2_177470070_177470297	0.90	Zfp970	zinc finger protein 970	5337	0.17
chr3_100189024_100189191	0.90	Gdap2	ganglioside-induced differentiation-associated-protein 2	5473	0.23
chr11_16811935_16812291	0.90	Egfros	epidermal growth factor receptor, opposite strand	18589	0.2
chr17_81368572_81368728	0.88	Gm50044	predicted gene, 50044	2183	0.4
chr14_8034997_8035230	0.88	Abhd6	abhydrolase domain containing 6	32147	0.13
chr4_103933550_103933744	0.87	Gm12719	predicted gene 12719	5894	0.25
chr12_104339796_104339996	0.86	Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	1410	0.24
chr8_26351792_26351988	0.86	Gm31784	predicted gene, 31784	39556	0.12
chr3_18210346_18210497	0.85	Gm23686	predicted gene, 23686	32796	0.17
chr13_93719775_93719928	0.85	AW495222	expressed sequence AW495222	676	0.6
chr4_80920883_80921053	0.83	Lurap1l	leucine rich adaptor protein 1-like	10322	0.26
chr9_57711329_57711506	0.81	Edc3	enhancer of mRNA decapping 3	2850	0.18
chr2_113790326_113790491	0.79	Grem1	gremlin 1, DAN family BMP antagonist	31762	0.15
chr3_115819747_115820078	0.79	Dph5	diphthamide biosynthesis 5	67925	0.08
chr13_115653702_115653853	0.79	Gm47892	predicted gene, 47892	65722	0.13
chr9_74695756_74695907	0.78	Gm27233	predicted gene 27233	13431	0.23
chr19_44394517_44394772	0.75	Scd1	stearoyl-Coenzyme A desaturase 1	12046	0.14
chr15_58961550_58961701	0.75	Mtss1	MTSS I-BAR domain containing 1	4785	0.16
chr6_72155996_72156358	0.74	Gm38832	predicted gene, 38832	6672	0.15
chr6_144709069_144709350	0.74	Sox5os4	SRY (sex determining region Y)-box 5, opposite strand 4	11702	0.16
chr15_55117700_55118060	0.73	Gm9920	predicted gene 9920	4203	0.17
chr9_122357372_122357607	0.73	Abhd5	abhydrolase domain containing 5	5700	0.15
chr6_149089096_149089247	0.73	Dennd5b	DENN/MADD domain containing 5B	3808	0.13
chr18_9832346_9832497	0.72	Gm23637	predicted gene, 23637	5302	0.16
chr19_40180796_40180958	0.72	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	6409	0.16
chr13_63665698_63665976	0.71	Gm47387	predicted gene, 47387	4040	0.18
chr18_33299657_33299808	0.71	Gm5503	predicted gene 5503	85223	0.09
chr2_34775525_34776380	0.71	Hspa5	heat shock protein 5	1105	0.4
chr15_73408554_73408705	0.71	Gm7908	predicted gene 7908	390	0.81
chr19_12685349_12685500	0.71	Gm49772	predicted gene, 49772	3653	0.11
chr1_67192772_67192960	0.70	Gm15668	predicted gene 15668	56334	0.12
chr14_17728323_17728474	0.70	Gm48320	predicted gene, 48320	42724	0.19
chr8_57653465_57653731	0.70	Galnt7	polypeptide N-acetylgalactosaminyltransferase 7	566	0.41
chr4_44920931_44921086	0.70	Zcchc7	zinc finger, CCHC domain containing 7	2110	0.25
chr7_118146005_118146156	0.70	Smg1	SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)	4281	0.18
chr16_42998647_42998825	0.69	Ndufs5-ps	NADH:ubiquinone oxidoreductase core subunit S5, pseudogene	43105	0.16
chr13_115067681_115067870	0.68	Gm10734	predicted gene 10734	21726	0.14
chr18_44453653_44453866	0.68	Mcc	mutated in colorectal cancers	65757	0.11
chr10_28228240_28228413	0.68	Gm22370	predicted gene, 22370	14205	0.29
chr6_119108994_119109155	0.68	Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	501	0.86
chr1_67215139_67215608	0.68	Gm15668	predicted gene 15668	33827	0.17
chr2_134539298_134539479	0.67	Hao1	hydroxyacid oxidase 1, liver	14919	0.28
chr9_106261948_106262435	0.67	Alas1	aminolevulinic acid synthase 1	13537	0.1
chr13_115096076_115096227	0.67	Gm49395	predicted gene, 49395	5473	0.14
chr4_109458656_109458807	0.66	Rnf11	ring finger protein 11	17944	0.15
chr9_103118235_103118386	0.66	Gm37166	predicted gene, 37166	2058	0.27
chr4_148616552_148616759	0.66	Tardbp	TAR DNA binding protein	325	0.81
chr11_86599706_86599919	0.66	Vmp1	vacuole membrane protein 1	2451	0.23
chr11_60199358_60199583	0.66	Mir6921	microRNA 6921	1147	0.3
chr9_122857713_122857864	0.65	Zfp445	zinc finger protein 445	288	0.82
chr16_42908893_42909236	0.65	Zbtb20	zinc finger and BTB domain containing 20	1412	0.39
chr1_172168265_172168469	0.65	Dcaf8	DDB1 and CUL4 associated factor 8	5587	0.11
chr4_6056446_6056603	0.65	Gm11797	predicted gene 11797	13350	0.28
chr5_40690611_40690784	0.65	Gm23022	predicted gene, 23022	284768	0.01
chr6_37510078_37510463	0.64	Akr1d1	aldo-keto reductase family 1, member D1	19903	0.21
chr11_50324646_50324797	0.64	Canx	calnexin	952	0.43
chr8_22888536_22888711	0.64	Gm45555	predicted gene 45555	15034	0.15
chr19_10181326_10181635	0.64	Fads1	fatty acid desaturase 1	1408	0.26
chr4_3321136_3321319	0.64	Gm11786	predicted gene 11786	5948	0.22
chr3_141967234_141967427	0.64	Bmpr1b	bone morphogenetic protein receptor, type 1B	14934	0.29
chr5_33465562_33465766	0.63	Gm43851	predicted gene 43851	28200	0.15
chr13_9060425_9060705	0.63	Gm36264	predicted gene, 36264	15886	0.13
chr7_39841684_39841835	0.63	4930558N11Rik	RIKEN cDNA 4930558N11 gene	44017	0.11
chr1_51914046_51914411	0.63	Myo1b	myosin IB	1684	0.29
chr6_136906748_136907166	0.63	Erp27	endoplasmic reticulum protein 27	15183	0.11
chr5_101742329_101742522	0.62	Cds1	CDP-diacylglycerol synthase 1	22705	0.14
chr10_42232281_42232611	0.62	Foxo3	forkhead box O3	25920	0.22
chr6_16551146_16551546	0.62	Gm36503	predicted gene, 36503	959	0.7
chr3_121643612_121643813	0.62	A730020M07Rik	RIKEN cDNA A730020M07 gene	227	0.92
chr3_32562720_32562907	0.61	Mfn1	mitofusin 1	95	0.96
chr4_22498530_22498747	0.61	Gm30731	predicted gene, 30731	8090	0.16
chr17_24236940_24237256	0.61	Mir5134	microRNA 5134	2494	0.12
chr3_48846432_48846591	0.60	Gm37190	predicted gene, 37190	85562	0.1
chr17_83843520_83843705	0.60	Haao	3-hydroxyanthranilate 3,4-dioxygenase	3137	0.22
chrX_42223380_42223551	0.60	Stag2	stromal antigen 2	71285	0.1
chr12_73861884_73862127	0.59	Gm15283	predicted gene 15283	7607	0.18
chr1_164543147_164543444	0.59	D630023O14Rik	RIKEN cDNA D630023O14 gene	32160	0.13
chr18_33436230_33436484	0.59	Nrep	neuronal regeneration related protein	27078	0.18
chr11_16761103_16761540	0.59	Egfr	epidermal growth factor receptor	9091	0.2
chr12_91560214_91560422	0.57	Gm25776	predicted gene, 25776	13254	0.16
chr1_21240946_21241097	0.57	Gsta3	glutathione S-transferase, alpha 3	392	0.76
chr18_39237141_39237343	0.57	Arhgap26	Rho GTPase activating protein 26	9874	0.26
chr5_89352355_89352713	0.57	Gc	vitamin D binding protein	83094	0.1
chr4_135787434_135787634	0.57	Myom3	myomesin family, member 3	10656	0.14
chr6_146125298_146125516	0.56	Itpr2	inositol 1,4,5-triphosphate receptor 2	21801	0.23
chr16_11135224_11135513	0.56	Txndc11	thioredoxin domain containing 11	718	0.49
chr15_67925007_67925168	0.56	Gm49409	predicted gene, 49409	17717	0.25
chr6_143857220_143857571	0.55	Sox5	SRY (sex determining region Y)-box 5	89693	0.09
chr7_134372608_134372831	0.55	D7Ertd443e	DNA segment, Chr 7, ERATO Doi 443, expressed	4106	0.34
chr14_88463900_88464058	0.54	Pcdh20	protocadherin 20	7367	0.23
chr13_20403622_20403794	0.54	Elmo1	engulfment and cell motility 1	69018	0.1
chr3_146260064_146260215	0.54	Lpar3	lysophosphatidic acid receptor 3	39176	0.13
chr10_68327935_68328096	0.54	4930545H06Rik	RIKEN cDNA 4930545H06 gene	6873	0.22
chr10_99222701_99222877	0.53	Gm34574	predicted gene, 34574	277	0.85
chr18_38923142_38923385	0.53	Fgf1	fibroblast growth factor 1	4492	0.24
chr13_4077186_4077340	0.53	Akr1c14	aldo-keto reductase family 1, member C14	991	0.44
chr2_122206384_122206535	0.53	Gm14050	predicted gene 14050	1461	0.25
chr2_177839201_177839672	0.53	Gm14325	predicted gene 14325	882	0.56
chr6_31453535_31453686	0.52	Mkln1	muskelin 1, intracellular mediator containing kelch motifs	14510	0.19
chr4_76366772_76366969	0.52	Ptprd	protein tyrosine phosphatase, receptor type, D	22627	0.21
chr6_119584715_119585189	0.52	Gm44317	predicted gene, 44317	14011	0.2
chr15_99038783_99039270	0.52	Tuba1c	tubulin, alpha 1C	8705	0.09
chr11_106667727_106667890	0.52	Pecam1	platelet/endothelial cell adhesion molecule 1	4482	0.2
chr13_94803722_94803937	0.51	Tbca	tubulin cofactor A	13905	0.18
chr8_84761164_84761339	0.51	Nfix	nuclear factor I/X	12145	0.11
chr2_71212098_71212533	0.51	Dync1i2	dynein cytoplasmic 1 intermediate chain 2	311	0.92
chr8_85504540_85504770	0.51	Gpt2	glutamic pyruvate transaminase (alanine aminotransferase) 2	11322	0.16
chr11_28702228_28702389	0.51	2810471M01Rik	RIKEN cDNA 2810471M01 gene	20744	0.15
chr2_42039612_42039773	0.51	Gm13461	predicted gene 13461	50863	0.18
chr13_28877494_28877645	0.50	2610307P16Rik	RIKEN cDNA 2610307P16 gene	5887	0.2
chr12_34997914_34998088	0.50	Prps1l1	phosphoribosyl pyrophosphate synthetase 1-like 1	13240	0.2
chr3_79845512_79845692	0.50	Tmem144	transmembrane protein 144	2690	0.24
chr11_16779721_16779963	0.50	Egfr	epidermal growth factor receptor	27612	0.17
chr6_141633750_141633901	0.50	Slco1b2	solute carrier organic anion transporter family, member 1b2	633	0.81
chr2_77522021_77522181	0.49	Zfp385b	zinc finger protein 385B	2483	0.38
chr10_34326839_34326990	0.49	Nt5dc1	5'-nucleotidase domain containing 1	13231	0.13
chr6_22341838_22341989	0.49	Fam3c	family with sequence similarity 3, member C	2000	0.42
chr11_120238015_120238347	0.49	Bahcc1	BAH domain and coiled-coil containing 1	1482	0.22
chr10_68131050_68131381	0.49	Arid5b	AT rich interactive domain 5B (MRF1-like)	5411	0.28
chr8_104787830_104787982	0.48	Gm45782	predicted gene 45782	2078	0.17
chr19_44386173_44386338	0.48	Scd1	stearoyl-Coenzyme A desaturase 1	20435	0.13
chr4_121168042_121168205	0.48	Rlf	rearranged L-myc fusion sequence	20411	0.12
chr11_67359982_67360339	0.48	Myh13	myosin, heavy polypeptide 13, skeletal muscle	4625	0.26
chr3_30609113_30609310	0.48	Mynn	myoneurin	4300	0.13
chr15_77307896_77308074	0.48	Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	981	0.5
chr6_124455872_124456023	0.48	Clstn3	calsyntenin 3	1938	0.2
chr13_4230959_4231234	0.48	Akr1c19	aldo-keto reductase family 1, member C19	2396	0.22
chr3_18877514_18877665	0.47	Gm30341	predicted gene, 30341	124512	0.06
chr2_32254540_32254691	0.47	Uck1	uridine-cytidine kinase 1	2054	0.14
chr13_43548363_43548529	0.47	Mcur1	mitochondrial calcium uniporter regulator 1	2326	0.24
chr2_58766481_58766674	0.47	Upp2	uridine phosphorylase 2	1252	0.49
chr7_84417589_84417755	0.47	Arnt2	aryl hydrocarbon receptor nuclear translocator 2	7496	0.17
chr2_72178406_72178610	0.47	Rapgef4	Rap guanine nucleotide exchange factor (GEF) 4	1185	0.5
chr16_43234125_43234650	0.47	Zbtb20	zinc finger and BTB domain containing 20	1493	0.45
chr9_53359307_53359484	0.47	Exph5	exophilin 5	18206	0.15
chr18_39459109_39459298	0.47	Nr3c1	nuclear receptor subfamily 3, group C, member 1	28029	0.2
chr6_28118749_28118957	0.46	Grm8	glutamate receptor, metabotropic 8	7272	0.25
chr5_87499331_87499512	0.46	Ugt2a1	UDP glucuronosyltransferase 2 family, polypeptide A1	8550	0.12
chr8_34157897_34158198	0.46	Saraf	store-operated calcium entry-associated regulatory factor	434	0.71
chr10_95413803_95413974	0.46	Socs2	suppressor of cytokine signaling 2	779	0.53
chr11_86614634_86614813	0.46	Vmp1	vacuole membrane protein 1	12428	0.15
chr13_112486027_112486262	0.46	Il6st	interleukin 6 signal transducer	11098	0.17
chr4_53596359_53596666	0.46	Slc44a1	solute carrier family 44, member 1	407	0.85
chr10_3109374_3109527	0.46	Gm30674	predicted gene, 30674	5331	0.15
chr11_80974682_80974867	0.46	Gm11416	predicted gene 11416	72020	0.1
chr13_46058970_46059151	0.45	Gm45949	predicted gene, 45949	1537	0.49
chr15_42717783_42717947	0.45	Angpt1	angiopoietin 1	40888	0.18
chr4_33310735_33311130	0.45	Rngtt	RNA guanylyltransferase and 5'-phosphatase	604	0.51
chr18_37761572_37761738	0.45	Pcdhgb8	protocadherin gamma subfamily B, 8	146	0.83
chr2_177397223_177397387	0.45	Gm14418	predicted gene 14418	1014	0.51
chr9_70446864_70447026	0.45	Rnf111	ring finger 111	6901	0.16
chr2_4895477_4895652	0.45	Sephs1	selenophosphate synthetase 1	11180	0.15
chr18_12668617_12668967	0.45	Gm41668	predicted gene, 41668	20373	0.13
chr17_5261920_5262119	0.45	Gm29050	predicted gene 29050	126744	0.05
chr8_77199905_77200064	0.45	Gm23260	predicted gene, 23260	5289	0.24
chr1_67204437_67204883	0.45	Gm15668	predicted gene 15668	44540	0.15
chr11_106468981_106469217	0.45	Ern1	endoplasmic reticulum (ER) to nucleus signalling 1	18697	0.14
chr1_67136982_67137399	0.45	Cps1	carbamoyl-phosphate synthetase 1	14164	0.23
chr15_51796404_51796577	0.45	Eif3h	eukaryotic translation initiation factor 3, subunit H	5941	0.26
chr11_51595976_51596127	0.45	Phykpl	5-phosphohydroxy-L-lysine phospholyase	3216	0.16
chr3_118487666_118487837	0.44	Gm26871	predicted gene, 26871	30092	0.12
chr9_42259997_42260195	0.44	Sc5d	sterol-C5-desaturase	4104	0.2
chr2_176635310_176635480	0.44	Gm14308	predicted gene 14308	923	0.55
chr13_112331091_112331250	0.44	Ankrd55	ankyrin repeat domain 55	12716	0.17
chr3_143103418_143103577	0.44	Gm43614	predicted gene 43614	4451	0.28
chr2_175738745_175738952	0.44	Gm2007	predicted gene 2007	2689	0.22
chr3_133348031_133348200	0.44	Ppa2	pyrophosphatase (inorganic) 2	39	0.98
chr9_79762117_79762289	0.44	Cox7a2	cytochrome c oxidase subunit 7A2	2325	0.25
chr11_89613753_89613946	0.43	Ankfn1	ankyrin-repeat and fibronectin type III domain containing 1	75293	0.12
chr11_111998446_111998808	0.43	Gm11679	predicted gene 11679	44951	0.19
chr1_136629198_136629381	0.43	Zfp281	zinc finger protein 281	4388	0.14
chr17_15050243_15050467	0.43	Ermard	ER membrane associated RNA degradation	10	0.97

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Lhx8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2	0.6	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.2	1.0	GO:0006526	arginine biosynthetic process(GO:0006526)
0.1	0.6	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
0.1	0.3	GO:0006768	biotin metabolic process(GO:0006768)
0.1	0.6	GO:0071763	nuclear membrane organization(GO:0071763)
0.1	0.3	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1	0.3	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.1	0.3	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.3	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.1	0.9	GO:0009404	toxin metabolic process(GO:0009404)
0.1	0.5	GO:0015871	choline transport(GO:0015871)
0.1	0.2	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.1	0.5	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.1	0.3	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1	0.3	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1	0.3	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	0.2	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.1	0.3	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1	0.9	GO:0009109	coenzyme catabolic process(GO:0009109)
0.1	0.3	GO:0032364	oxygen homeostasis(GO:0032364)
0.1	0.1	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.1	0.1	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
0.1	0.2	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1	0.2	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1	0.3	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.1	0.2	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.1	0.4	GO:1902222	L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1	0.2	GO:0003383	apical constriction(GO:0003383)
0.1	0.2	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.1	0.2	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1	0.3	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.1	0.3	GO:1900094	nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry(GO:1900094) nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900164)
0.1	0.2	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.1	0.4	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	1.1	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.3	GO:0046874	quinolinate metabolic process(GO:0046874)
0.0	0.1	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.0	0.1	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.0	0.1	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0	0.1	GO:0015770	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.2	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0	0.2	GO:0018214	protein carboxylation(GO:0018214)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.2	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.2	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.1	GO:0008050	female courtship behavior(GO:0008050)
0.0	0.3	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	0.1	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0	0.5	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.3	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.2	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.1	GO:0042126	nitrate metabolic process(GO:0042126)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.1	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.1	GO:0052695	cellular glucuronidation(GO:0052695)
0.0	0.1	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.4	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.1	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0	0.1	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.0	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	1.0	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.1	GO:0035910	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0	0.2	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.2	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.1	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.1	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0	0.1	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.3	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.1	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.1	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	0.3	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.0	0.1	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.2	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.1	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0	0.2	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655)
0.0	0.1	GO:0061010	gall bladder development(GO:0061010)
0.0	0.3	GO:0006622	protein targeting to lysosome(GO:0006622)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.6	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.2	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.1	GO:1900135	positive regulation of renin secretion into blood stream(GO:1900135)
0.0	0.2	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	0.1	GO:0061072	iris morphogenesis(GO:0061072)
0.0	0.0	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.0	0.2	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.1	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0	0.1	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.0	GO:1903999	negative regulation of eating behavior(GO:1903999)
0.0	0.1	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.2	GO:1902855	regulation of nonmotile primary cilium assembly(GO:1902855)
0.0	0.1	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.0	0.1	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.0	0.1	GO:0050904	diapedesis(GO:0050904)
0.0	0.0	GO:1904251	regulation of bile acid metabolic process(GO:1904251)
0.0	0.1	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.1	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.0	0.1	GO:0035627	ceramide transport(GO:0035627)
0.0	0.1	GO:0048633	positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0	0.0	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
0.0	0.1	GO:0072602	interleukin-4 secretion(GO:0072602)
0.0	0.1	GO:0015747	urate transport(GO:0015747)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:1900378	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.2	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.1	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.3	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:1900133	regulation of renin secretion into blood stream(GO:1900133)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0034756	regulation of iron ion transport(GO:0034756)
0.0	0.1	GO:0072092	ureteric bud invasion(GO:0072092)
0.0	0.2	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.0	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0	0.1	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0	0.1	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.1	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0	0.1	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.0	0.0	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0	0.3	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.1	GO:0010612	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0	0.2	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.1	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.1	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.0	0.0	GO:0014732	skeletal muscle atrophy(GO:0014732)
0.0	0.0	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.0	0.1	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.0	0.1	GO:0072643	interferon-gamma secretion(GO:0072643)
0.0	0.1	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.0	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
0.0	0.1	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.2	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0	0.1	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.0	0.1	GO:0018211	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.1	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.0	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.0	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.0	GO:0006172	ADP biosynthetic process(GO:0006172)
0.0	0.1	GO:1903069	regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.0	0.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.0	GO:0003162	atrioventricular node development(GO:0003162)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.0	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.0	0.1	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.2	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.2	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.0	GO:0072361	regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0	0.0	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0	0.1	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
0.0	0.0	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.0	GO:0050883	musculoskeletal movement, spinal reflex action(GO:0050883)
0.0	0.0	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.0	GO:0060005	vestibular reflex(GO:0060005)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.0	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.0	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.0	GO:0000087	mitotic M phase(GO:0000087)
0.0	0.1	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	0.0	GO:0009188	ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.1	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.0	GO:0040031	snRNA modification(GO:0040031)
0.0	0.0	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.0	0.0	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.0	GO:0071494	cellular response to UV-C(GO:0071494)
0.0	0.2	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.0	GO:0060336	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.1	GO:0071361	cellular response to ethanol(GO:0071361)
0.0	0.1	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.0	0.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0048382	mesendoderm development(GO:0048382)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0	0.1	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.2	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.0	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0	0.0	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0	0.1	GO:0015867	ATP transport(GO:0015867)
0.0	0.0	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.0	0.2	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.1	GO:0046606	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.1	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.1	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.1	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	0.0	GO:0070197	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.1	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.0	GO:0060353	regulation of cell adhesion molecule production(GO:0060353)
0.0	0.1	GO:0007135	meiosis II(GO:0007135)
0.0	0.0	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.2	GO:0019430	removal of superoxide radicals(GO:0019430)
0.0	0.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.0	GO:0043974	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0	0.0	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.0	GO:1903423	positive regulation of synaptic vesicle recycling(GO:1903423)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.2	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.1	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.3	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.1	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.0	0.1	GO:0002024	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0	0.1	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.0	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.0	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0	0.1	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.0	0.0	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.0	GO:0086017	Purkinje myocyte action potential(GO:0086017)
0.0	0.0	GO:0006971	hypotonic response(GO:0006971)
0.0	0.1	GO:0031269	pseudopodium assembly(GO:0031269)
0.0	0.0	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.0	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.0	GO:0006063	uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.6	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.6	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.1	0.2	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	0.2	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	0.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.2	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.2	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.2	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.3	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.2	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.6	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.4	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.3	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.0	0.3	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	1.0	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.2	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0033648	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0	0.1	GO:0044308	axonal spine(GO:0044308)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.4	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0033263	CORVET complex(GO:0033263)
0.0	0.2	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.3	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.0	GO:0097413	Lewy body(GO:0097413)
0.0	0.1	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.2	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533)
0.0	0.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.1	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.3	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.0	GO:0031502	dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0	0.0	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
0.0	0.2	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.1	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.1	GO:0005610	laminin-5 complex(GO:0005610)
0.0	0.2	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.2	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	0.1	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.0	0.0	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.0	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.3	0.9	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.2	0.7	GO:0048408	epidermal growth factor binding(GO:0048408)
0.2	0.6	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1	0.4	GO:0004771	sterol esterase activity(GO:0004771)
0.1	0.4	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.1	0.4	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.4	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.5	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.1	0.2	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1	0.2	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1	0.3	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1	0.3	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.1	0.3	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1	0.1	GO:0000009	alpha-1,6-mannosyltransferase activity(GO:0000009)
0.1	0.2	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	0.2	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1	0.2	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.1	0.2	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.1	0.2	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.1	0.6	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.2	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.2	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0	0.1	GO:0008515	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.2	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.2	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.3	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.2	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.2	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.3	GO:0034796	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0	0.2	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.2	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
0.0	0.2	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0035671	enone reductase activity(GO:0035671)
0.0	1.0	GO:0080031	prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.1	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.0	GO:0051723	protein methylesterase activity(GO:0051723)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0030572	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.0	0.1	GO:0097001	ceramide binding(GO:0097001)
0.0	0.4	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.2	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.0	0.2	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.1	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0070191	methionine-R-sulfoxide reductase activity(GO:0070191)
0.0	0.4	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.6	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.1	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.0	0.1	GO:0016015	morphogen activity(GO:0016015)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.3	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.2	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.6	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.3	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.0	0.2	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.1	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.0	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.1	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0004556	alpha-amylase activity(GO:0004556)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.0	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0018573	2,3-dihydroxy DDT 1,2-dioxygenase activity(GO:0018542) phenanthrene dioxygenase activity(GO:0018555) 2,2',3-trihydroxybiphenyl dioxygenase activity(GO:0018556) 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity(GO:0018557) 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity(GO:0018558) 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity(GO:0018559) protocatechuate 3,4-dioxygenase type II activity(GO:0018560) 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity(GO:0018561) 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity(GO:0018562) 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity(GO:0018563) carbazole 1,9a-dioxygenase activity(GO:0018564) dihydroxydibenzothiophene dioxygenase activity(GO:0018565) 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity(GO:0018566) styrene dioxygenase activity(GO:0018567) 3,4-dihydroxyphenanthrene dioxygenase activity(GO:0018568) hydroquinone 1,2-dioxygenase activity(GO:0018569) p-cumate 2,3-dioxygenase activity(GO:0018570) 2,3-dihydroxy-p-cumate dioxygenase activity(GO:0018571) 3,5-dichlorocatechol 1,2-dioxygenase activity(GO:0018572) 2-aminophenol 1,6-dioxygenase activity(GO:0018573) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity(GO:0018574) chlorocatechol 1,2-dioxygenase activity(GO:0018575) catechol dioxygenase activity(GO:0019114) dihydroxyfluorene dioxygenase activity(GO:0019117) 5-aminosalicylate dioxygenase activity(GO:0034543) 3-hydroxy-2-naphthoate 2,3-dioxygenase activity(GO:0034803) benzo(a)pyrene 11,12-dioxygenase activity(GO:0034806) benzo(a)pyrene 4,5-dioxygenase activity(GO:0034808) 4,5-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034810) benzo(a)pyrene 9,10-dioxygenase activity(GO:0034811) 9,10-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034812) benzo(a)pyrene 7,8-dioxygenase activity(GO:0034813) 7,8-dihydroxy benzo(a)pyrene dioxygenase activity(GO:0034814) 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity(GO:0034827) 2-mercaptobenzothiazole dioxygenase activity(GO:0034834) pyridine-3,4-diol dioxygenase activity(GO:0034895) pyrene dioxygenase activity(GO:0034920) 4,5-dihydroxypyrene dioxygenase activity(GO:0034922) phenanthrene-4-carboxylate dioxygenase activity(GO:0034934) tetrachlorobenzene dioxygenase activity(GO:0034935) 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity(GO:0034936) 2,3-dihydroxydiphenyl ether dioxygenase activity(GO:0034955) diphenyl ether 1,2-dioxygenase activity(GO:0034956) arachidonate 8(S)-lipoxygenase activity(GO:0036403) 4-hydroxycatechol 1,2-dioxygenase activity(GO:0047074)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.1	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.0	0.1	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0	0.1	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.2	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0	0.1	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	1.4	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.0	GO:0070538	oleic acid binding(GO:0070538)
0.0	0.2	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.2	GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters(GO:0016893)
0.0	0.1	GO:0047105	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0	0.0	GO:0016880	acid-ammonia (or amide) ligase activity(GO:0016880)
0.0	0.1	GO:0032557	pyrimidine ribonucleotide binding(GO:0032557)
0.0	0.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.0	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.0	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.0	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.1	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.0	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	0.0	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.1	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.1	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.2	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.0	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.0	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.0	0.0	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.0	0.0	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.5	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.0	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.1	GO:0070728	leucine binding(GO:0070728)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.1	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.0	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.1	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.0	GO:0042171	lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0	0.1	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.0	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.0	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.4	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.4	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.4	PID BMP PATHWAY	BMP receptor signaling
0.0	0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.4	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.3	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.2	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.7	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.6	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.7	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.3	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.6	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.0	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.0	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.4	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.3	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.3	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.2	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.3	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.1	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling

Results for Lhx8

Z-value: 1.95

Motif logo

Transcription factors associated with Lhx8

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Lhx8 motif across conditions

Conditions sorted by the z-value of the Lhx8 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Lhx8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: