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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Mafa

Z-value: 0.93

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Transcription factors associated with Mafa

Gene Symbol Gene ID Gene Info
Mafa
ENSMUSG00000047591.4 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr15_75748699_75748884Mafa5630.657377-0.768.1e-02Click!
chr15_75748359_75748528Mafa2150.899459-0.572.4e-01Click!
chr15_75748161_75748312Mafa80.964253-0.522.9e-01Click!

Activity of the Mafa motif across conditions

Conditions sorted by the z-value of the Mafa motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr15_27466172_27467167 0.52 Ank
 progressive ankylosis
 8
 0.97
chr11_4378478_4378660 0.51 Hormad2
 HORMA domain containing 2
 48693
 0.1
chr17_46052256_46052407 0.48 Vegfa
 vascular endothelial growth factor A
 19962
 0.13
chr13_45717276_45717427 0.42 Gm47460
 predicted gene, 47460
 32221
 0.22
chr19_40155227_40155577 0.38 Cyp2c70
 cytochrome P450, family 2, subfamily c, polypeptide 70
 31884
 0.13
chr3_52649145_52649332 0.37 Gm10293
 predicted pseudogene 10293
 36403
 0.17
chr8_69090324_69090475 0.37 Slc18a1
 solute carrier family 18 (vesicular monoamine), member 1
 1164
 0.38
chr2_44113422_44113573 0.36 Arhgap15os
 Rho GTPase activating protein 15, opposite strand
 48173
 0.17
chr17_28761439_28761590 0.35 Mapk13
 mitogen-activated protein kinase 13
 7783
 0.12
chr11_82527093_82527250 0.34 Gm24612
 predicted gene, 24612
 69008
 0.09
chr11_83721035_83721187 0.34 Wfdc18
 WAP four-disulfide core domain 18
 11986
 0.08
chr5_53278040_53278387 0.34 Smim20
 small integral membrane protein 20
 1095
 0.48
chr2_153444307_153444698 0.33 Nol4l
 nucleolar protein 4-like
 23
 0.98
chr19_4493105_4493260 0.33 2010003K11Rik
 RIKEN cDNA 2010003K11 gene
 5401
 0.13
chr7_90099485_90099651 0.32 Gm5341
 predicted pseudogene 5341
 8400
 0.13
chrX_36823954_36824173 0.32 Gm14549
 predicted gene 14549
 9292
 0.12
chr5_122320451_122320627 0.32 Gm15842
 predicted gene 15842
 18117
 0.09
chr17_8769269_8769442 0.31 Gm15426
 predicted gene 15426
 3428
 0.29
chr17_25127135_25127453 0.31 Clcn7
 chloride channel, voltage-sensitive 7
 6097
 0.1
chr19_16437834_16438025 0.30 Gna14
 guanine nucleotide binding protein, alpha 14
 1371
 0.4
chr3_52531720_52531871 0.30 Gm30173
 predicted gene, 30173
 14831
 0.23
chr13_63293654_63293805 0.28 Aopep
 aminopeptidase O
 5064
 0.09
chr6_51325666_51325826 0.28 Gm32479
 predicted gene, 32479
 37891
 0.14
chr6_90568297_90568448 0.27 Aldh1l1
 aldehyde dehydrogenase 1 family, member L1
 666
 0.63
chr4_108362975_108363166 0.27 Shisal2a
 shisa like 2A
 20279
 0.11
chr13_112331307_112331468 0.27 Ankrd55
 ankyrin repeat domain 55
 12933
 0.17
chr15_61098917_61099257 0.27 Gm38563
 predicted gene, 38563
 58782
 0.13
chr6_144709069_144709350 0.26 Sox5os4
 SRY (sex determining region Y)-box 5, opposite strand 4
 11702
 0.16
chr2_165442563_165442717 0.26 Gm14437
 predicted gene 14437
 376
 0.82
chr1_131278227_131278383 0.26 Ikbke
 inhibitor of kappaB kinase epsilon
 1301
 0.32
chr5_129846397_129846548 0.24 Sumf2
 sulfatase modifying factor 2
 514
 0.59
chr9_94705415_94705619 0.24 Gm16262
 predicted gene 16262
 3198
 0.23
chr17_81389463_81389664 0.23 Gm50044
 predicted gene, 50044
 18730
 0.23
chr3_51251932_51252083 0.23 Elf2
 E74-like factor 2
 8234
 0.13
chr7_27452561_27452934 0.23 Blvrb
 biliverdin reductase B (flavin reductase (NADPH))
 303
 0.79
chr1_88702033_88702468 0.22 Arl4c
 ADP-ribosylation factor-like 4C
 29
 0.97
chr1_21247881_21248070 0.22 Gsta3
 glutathione S-transferase, alpha 3
 5546
 0.12
chr2_52580732_52580891 0.22 Cacnb4
 calcium channel, voltage-dependent, beta 4 subunit
 22244
 0.17
chr3_51231004_51231169 0.22 Gm38357
 predicted gene, 38357
 831
 0.53
chr14_86346221_86346400 0.22 Gm4350
 predicted gene 4350
 26025
 0.13
chr3_27562067_27562227 0.22 Gm43344
 predicted gene 43344
 15506
 0.22
chr8_126928052_126928350 0.21 Gm26397
 predicted gene, 26397
 16779
 0.14
chr18_32271671_32271889 0.21 Ercc3
 excision repair cross-complementing rodent repair deficiency, complementation group 3
 14511
 0.2
chr11_120817696_120817936 0.21 Fasn
 fatty acid synthase
 2361
 0.15
chrY_90792035_90792186 0.21 Gm47283
 predicted gene, 47283
 1659
 0.36
chr6_28755592_28755775 0.21 Snd1
 staphylococcal nuclease and tudor domain containing 1
 9007
 0.22
chrX_170017443_170017594 0.21 Erdr1
 erythroid differentiation regulator 1
 6774
 0.18
chr11_115898937_115899098 0.21 Smim5
 small integral membrane protein 5
 949
 0.35
chr3_52985515_52985857 0.21 Cog6
 component of oligomeric golgi complex 6
 8999
 0.16
chr9_106238560_106238771 0.20 Alas1
 aminolevulinic acid synthase 1
 65
 0.95
chr11_64842929_64843090 0.20 Gm12292
 predicted gene 12292
 744
 0.76
chr3_51230122_51230437 0.20 Gm38357
 predicted gene, 38357
 1638
 0.29
chrX_12792421_12792582 0.19 Gm14634
 predicted gene 14634
 29957
 0.15
chr16_30968839_30969241 0.19 Gm15742
 predicted gene 15742
 4478
 0.21
chr2_44106392_44106564 0.19 Arhgap15os
 Rho GTPase activating protein 15, opposite strand
 41154
 0.18
chr9_44087034_44087185 0.19 Usp2
 ubiquitin specific peptidase 2
 81
 0.91
chr10_5424273_5424447 0.19 Syne1
 spectrin repeat containing, nuclear envelope 1
 55874
 0.14
chr9_122027805_122027998 0.19 Gm47117
 predicted gene, 47117
 15761
 0.1
chr1_151243904_151244075 0.19 Gm24402
 predicted gene, 24402
 16925
 0.12
chr1_162891657_162891835 0.19 Fmo2
 flavin containing monooxygenase 2
 5231
 0.19
chr1_133370822_133370973 0.19 Etnk2
 ethanolamine kinase 2
 3610
 0.17
chr7_52391946_52392105 0.18 Gm20074
 predicted gene, 20074
 19428
 0.28
chr10_4599676_4599928 0.18 Esr1
 estrogen receptor 1 (alpha)
 11791
 0.21
chr9_61911741_61911892 0.18 Rplp1
 ribosomal protein, large, P1
 2726
 0.27
chr5_115515109_115515270 0.18 Gm13840
 predicted gene 13840
 74
 0.92
chr3_117078252_117078413 0.18 1700061I17Rik
 RIKEN cDNA 1700061I17 gene
 567
 0.75
chr14_25312206_25312357 0.18 Gm26660
 predicted gene, 26660
 66354
 0.1
chr6_83797123_83797297 0.18 Nagk
 N-acetylglucosamine kinase
 178
 0.88
chr13_107469451_107469885 0.18 AI197445
 expressed sequence AI197445
 154
 0.97
chr5_120481198_120481714 0.18 Gm15690
 predicted gene 15690
 553
 0.54
chr17_14988060_14988226 0.17 9030025P20Rik
 RIKEN cDNA 9030025P20 gene
 8644
 0.11
chr6_90746922_90747105 0.17 Iqsec1
 IQ motif and Sec7 domain 1
 10326
 0.17
chr1_21166525_21166783 0.17 Gm2693
 predicted gene 2693
 12334
 0.16
chr16_90283788_90283943 0.17 Scaf4
 SR-related CTD-associated factor 4
 443
 0.8
chr11_16900676_16901084 0.17 Egfr
 epidermal growth factor receptor
 4305
 0.23
chr8_25636930_25637092 0.17 Nsd3
 nuclear receptor binding SET domain protein 3
 3273
 0.13
chr17_87302277_87302563 0.17 Ttc7
 tetratricopeptide repeat domain 7
 6912
 0.15
chr12_31499269_31499433 0.17 Cbll1
 Casitas B-lineage lymphoma-like 1
 204
 0.88
chr5_121564754_121565431 0.17 Aldh2
 aldehyde dehydrogenase 2, mitochondrial
 6095
 0.1
chr11_120568518_120568669 0.16 P4hb
 prolyl 4-hydroxylase, beta polypeptide
 4248
 0.07
chr13_44735230_44735426 0.16 Jarid2
 jumonji, AT rich interactive domain 2
 1288
 0.56
chr17_5849675_5849852 0.16 Snx9
 sorting nexin 9
 8411
 0.15
chr9_61348025_61348190 0.16 Gm10655
 predicted gene 10655
 23520
 0.16
chr8_84842789_84843130 0.16 Calr
 calreticulin
 1957
 0.13
chr17_47976252_47976712 0.16 Gm14871
 predicted gene 14871
 27090
 0.11
chr13_8865143_8865294 0.16 Wdr37
 WD repeat domain 37
 3993
 0.12
chr11_6026043_6026414 0.16 Camk2b
 calcium/calmodulin-dependent protein kinase II, beta
 25780
 0.15
chr8_121973410_121973561 0.16 Gm17709
 predicted gene, 17709
 337
 0.72
chr11_67142292_67142463 0.16 2310065F04Rik
 RIKEN cDNA 2310065F04 gene
 22297
 0.12
chr8_109969231_109969458 0.16 Gm45795
 predicted gene 45795
 5008
 0.14
chr15_58927649_58927810 0.16 Tatdn1
 TatD DNase domain containing 1
 5639
 0.14
chr1_52631028_52631204 0.16 Nemp2
 nuclear envelope integral membrane protein 2
 319
 0.86
chr17_48598725_48598879 0.16 Gm24071
 predicted gene, 24071
 19021
 0.19
chr4_143021381_143021546 0.16 6330411D24Rik
 RIKEN cDNA 6330411D24 gene
 52303
 0.14
chr6_15828886_15829037 0.16 Gm43990
 predicted gene, 43990
 7128
 0.25
chr3_18251077_18251277 0.16 Cyp7b1
 cytochrome P450, family 7, subfamily b, polypeptide 1
 7839
 0.24
chr5_36390576_36390854 0.16 Sorcs2
 sortilin-related VPS10 domain containing receptor 2
 7392
 0.21
chr4_36014169_36014515 0.16 Gm12369
 predicted gene 12369
 10163
 0.27
chr11_5524215_5524690 0.16 Xbp1
 X-box binding protein 1
 2529
 0.2
chr9_121555731_121555882 0.15 Gm47095
 predicted gene, 47095
 19655
 0.13
chr10_87880307_87880601 0.15 Igf1os
 insulin-like growth factor 1, opposite strand
 17073
 0.18
chr5_123907365_123907778 0.15 Denr
 density-regulated protein
 82
 0.95
chr1_186250377_186250604 0.15 Gm37272
 predicted gene, 37272
 68233
 0.1
chr17_28010581_28010732 0.15 Anks1
 ankyrin repeat and SAM domain containing 1
 3311
 0.15
chr7_126932811_126932965 0.15 Kctd13
 potassium channel tetramerisation domain containing 13
 2967
 0.08
chr5_77309423_77309744 0.15 Noa1
 nitric oxide associated 1
 476
 0.48
chr15_59016273_59016565 0.15 Mtss1
 MTSS I-BAR domain containing 1
 24177
 0.16
chr11_120820263_120820477 0.15 Fasn
 fatty acid synthase
 3410
 0.12
chr3_41614429_41614618 0.15 Jade1
 jade family PHD finger 1
 12093
 0.16
chr15_27585587_27585755 0.15 Mir7117
 microRNA 7117
 14177
 0.15
chr18_12671580_12671783 0.15 Ttc39c
 tetratricopeptide repeat domain 39C
 18047
 0.13
chr19_38015663_38015814 0.15 Myof
 myoferlin
 27613
 0.14
chr11_97363051_97363241 0.15 Socs7
 suppressor of cytokine signaling 7
 595
 0.66
chr15_100228265_100228661 0.15 Atf1
 activating transcription factor 1
 200
 0.92
chr17_46139458_46139771 0.14 Rsph9
 radial spoke head 9 homolog (Chlamydomonas)
 2784
 0.15
chr9_44478965_44479362 0.14 C030014I23Rik
 RIKEN cDNA C030014I23 gene
 385
 0.49
chr10_81408031_81408226 0.14 Nfic
 nuclear factor I/C
 487
 0.49
chr6_142788740_142788928 0.14 Sult6b2
 sulfotransferase family 6B, member 2
 15632
 0.16
chr8_93108415_93108795 0.14 Ces1c
 carboxylesterase 1C
 15924
 0.14
chr2_134534653_134534804 0.14 Hao1
 hydroxyacid oxidase 1, liver
 19579
 0.27
chr7_122066462_122066699 0.14 Ears2
 glutamyl-tRNA synthetase 2, mitochondrial
 431
 0.53
chr2_34777307_34777554 0.14 Hspa5
 heat shock protein 5
 2583
 0.19
chr18_76305906_76306080 0.14 Gm50360
 predicted gene, 50360
 15831
 0.21
chr3_97635501_97635936 0.14 Fmo5
 flavin containing monooxygenase 5
 6835
 0.14
chr4_117126763_117126969 0.14 Tctex1d4
 Tctex1 domain containing 4
 53
 0.9
chr14_65759139_65759314 0.14 Pbk
 PDZ binding kinase
 46611
 0.13
chr2_58786750_58786901 0.14 Upp2
 uridine phosphorylase 2
 21500
 0.19
chr5_4918481_4918656 0.14 Cdk14
 cyclin-dependent kinase 14
 29656
 0.14
chr6_29815607_29815784 0.14 Ahcyl2
 S-adenosylhomocysteine hydrolase-like 2
 13836
 0.18
chr5_123022889_123023101 0.14 Orai1
 ORAI calcium release-activated calcium modulator 1
 7657
 0.09
chr6_134517015_134517190 0.14 Lrp6
 low density lipoprotein receptor-related protein 6
 24612
 0.17
chr1_162892140_162892544 0.14 Fmo2
 flavin containing monooxygenase 2
 5827
 0.19
chr3_94697991_94698327 0.14 Selenbp2
 selenium binding protein 2
 4500
 0.13
chr2_20666086_20666239 0.14 Gm13362
 predicted gene 13362
 47072
 0.16
chr3_21371390_21371542 0.14 Gm29137
 predicted gene 29137
 102376
 0.08
chr13_109536856_109537007 0.14 Pde4d
 phosphodiesterase 4D, cAMP specific
 44474
 0.21
chr11_28698214_28698534 0.14 2810471M01Rik
 RIKEN cDNA 2810471M01 gene
 16810
 0.16
chr11_60256374_60256525 0.14 Tom1l2
 target of myb1-like 2 (chicken)
 10780
 0.12
chr11_87456055_87456225 0.14 Rnu3b4
 U3B small nuclear RNA 4
 6146
 0.09
chr15_76208375_76208737 0.14 Plec
 plectin
 97
 0.92
chr3_94937900_94938079 0.14 Selenbp1
 selenium binding protein 1
 4830
 0.1
chr13_37831757_37832025 0.14 Rreb1
 ras responsive element binding protein 1
 4498
 0.22
chr13_84221796_84222007 0.13 A230107N01Rik
 RIKEN cDNA A230107N01 gene
 199
 0.71
chr13_63520249_63520412 0.13 Ptch1
 patched 1
 8301
 0.15
chr12_104087488_104087669 0.13 Serpina4-ps1
 serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1
 6929
 0.1
chr3_89140809_89141081 0.13 Pklr
 pyruvate kinase liver and red blood cell
 4322
 0.08
chr12_28629267_28629434 0.13 Rps7
 ribosomal protein S7
 2567
 0.2
chr7_80030553_80030704 0.13 Zfp710
 zinc finger protein 710
 2814
 0.17
chr7_34226952_34227127 0.13 Gpi1
 glucose-6-phosphate isomerase 1
 1958
 0.17
chr4_63251381_63251799 0.13 Mir455
 microRNA 455
 5261
 0.19
chr9_92350909_92351360 0.13 1700057G04Rik
 RIKEN cDNA 1700057G04 gene
 49
 0.97
chr11_104441511_104441826 0.13 Kansl1
 KAT8 regulatory NSL complex subunit 1
 34
 0.97
chr2_181044162_181044343 0.13 Chrna4
 cholinergic receptor, nicotinic, alpha polypeptide 4
 706
 0.59
chr17_71215570_71215721 0.13 Lpin2
 lipin 2
 10969
 0.16
chr1_58382672_58382837 0.13 Gm37607
 predicted gene, 37607
 3380
 0.17
chr9_45095657_45095825 0.13 Jaml
 junction adhesion molecule like
 7053
 0.09
chr10_21678793_21678948 0.13 Gm5420
 predicted gene 5420
 7541
 0.23
chr6_72360494_72360859 0.13 Rnf181
 ring finger protein 181
 391
 0.72
chr13_48972078_48972229 0.13 Fam120a
 family with sequence similarity 120, member A
 4136
 0.28
chr19_10046514_10046840 0.13 Fads3
 fatty acid desaturase 3
 4945
 0.14
chr2_160249478_160249680 0.12 Gm826
 predicted gene 826
 64037
 0.13
chr8_84723357_84723534 0.12 G430095P16Rik
 RIKEN cDNA G430095P16 gene
 438
 0.7
chr9_45205284_45205435 0.12 Tmprss4
 transmembrane protease, serine 4
 1267
 0.29
chr13_55211103_55211935 0.12 Nsd1
 nuclear receptor-binding SET-domain protein 1
 22
 0.97
chr13_44291297_44291488 0.12 Gm29676
 predicted gene, 29676
 10943
 0.21
chr3_116162254_116162405 0.12 Gm26544
 predicted gene, 26544
 11850
 0.13
chr4_3937763_3937914 0.12 Plag1
 pleiomorphic adenoma gene 1
 544
 0.59
chr2_70798855_70799007 0.12 Tlk1
 tousled-like kinase 1
 26297
 0.18
chr16_95605411_95605586 0.12 Erg
 ETS transcription factor
 18905
 0.24
chr6_13677230_13677408 0.12 Bmt2
 base methyltransferase of 25S rRNA 2
 619
 0.8
chr18_60217937_60218088 0.12 Gm5970
 predicted gene 5970
 2831
 0.21
chr5_118649962_118650113 0.12 Gm43274
 predicted gene 43274
 5664
 0.18
chr13_93710471_93710659 0.12 Dmgdh
 dimethylglycine dehydrogenase precursor
 974
 0.45
chr10_39209250_39209435 0.12 Gm6477
 predicted gene 6477
 10804
 0.16
chr17_15019435_15019586 0.12 Gm3435
 predicted gene 3435
 9175
 0.12
chr15_85720937_85721131 0.12 Mirlet7b
 microRNA let7b
 13715
 0.13
chr6_71458715_71458866 0.12 Gm44172
 predicted gene, 44172
 6798
 0.11
chr19_30092253_30092507 0.12 Uhrf2
 ubiquitin-like, containing PHD and RING finger domains 2
 419
 0.86
chr7_139703566_139703726 0.12 Rpl21-ps13
 ribosomal protein L21-ps13
 15753
 0.15
chr8_126876394_126876573 0.12 Gm31718
 predicted gene, 31718
 45
 0.98
chr11_60251360_60251526 0.12 Tom1l2
 target of myb1-like 2 (chicken)
 5774
 0.13
chr11_102404567_102404909 0.12 Slc25a39
 solute carrier family 25, member 39
 245
 0.47
chrX_60013443_60013609 0.12 F9
 coagulation factor IX
 14062
 0.2
chr19_21599131_21599282 0.12 1110059E24Rik
 RIKEN cDNA 1110059E24 gene
 5113
 0.24
chr17_33932704_33933052 0.12 Rgl2
 ral guanine nucleotide dissociation stimulator-like 2
 747
 0.27
chr17_29431315_29431488 0.12 Gm36199
 predicted gene, 36199
 1434
 0.29
chr13_55212302_55212785 0.12 Nsd1
 nuclear receptor-binding SET-domain protein 1
 157
 0.94
chr3_94399233_94399394 0.12 Lingo4
 leucine rich repeat and Ig domain containing 4
 796
 0.33
chr13_97138128_97138479 0.12 Gfm2
 G elongation factor, mitochondrial 2
 263
 0.59
chr8_105084813_105085337 0.12 Ces3b
 carboxylesterase 3B
 1312
 0.28
chr9_121799708_121799875 0.12 Hhatl
 hedgehog acyltransferase-like
 7284
 0.09
chr1_134764237_134764440 0.11 Ppp1r12b
 protein phosphatase 1, regulatory subunit 12B
 3985
 0.18
chr19_30229320_30229513 0.11 Mbl2
 mannose-binding lectin (protein C) 2
 3526
 0.25
chr5_24502879_24503079 0.11 Agap3
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
 22807
 0.08
chr6_29523600_29523797 0.11 Irf5
 interferon regulatory factor 5
 2927
 0.15
chr17_28436263_28436419 0.11 Fkbp5
 FK506 binding protein 5
 4669
 0.12
chr1_82158565_82158766 0.11 Mir6344
 microRNA 6344
 26749
 0.19
chr9_48604518_48604682 0.11 Nnmt
 nicotinamide N-methyltransferase
 477
 0.86
chr12_80231463_80231884 0.11 Gm47767
 predicted gene, 47767
 22430
 0.13
chr8_36265736_36265923 0.11 Lonrf1
 LON peptidase N-terminal domain and ring finger 1
 16313
 0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Mafa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.2 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.3 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.2 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.1 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0097195 pilomotor reflex(GO:0097195)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0 0.1 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0 0.1 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.0 0.1 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.1 GO:0000101 sulfur amino acid transport(GO:0000101)
0.0 0.1 GO:0010046 response to mycotoxin(GO:0010046)
0.0 0.1 GO:0036166 phenotypic switching(GO:0036166)
0.0 0.1 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.0 0.1 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.1 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.0 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.1 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.0 0.1 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.0 GO:0048290 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.2 GO:0061032 visceral serous pericardium development(GO:0061032)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.1 GO:0051031 tRNA transport(GO:0051031)
0.0 0.1 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.1 GO:2001260 regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.0 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.0 GO:0033122 negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.1 GO:0006407 rRNA export from nucleus(GO:0006407)
0.0 0.0 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.0 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0006573 valine metabolic process(GO:0006573)
0.0 0.0 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.0 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.0 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.0 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
0.0 0.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.0 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.0 0.0 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.0 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.0 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.0 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.0 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.0 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.0 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.0 GO:0030167 proteoglycan catabolic process(GO:0030167)
0.0 0.0 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.0 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.0 GO:0000087 mitotic M phase(GO:0000087)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.0 GO:0061043 regulation of vascular wound healing(GO:0061043)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.0 GO:0046469 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.0 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.0 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.0 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.3 GO:0019145 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0032564 dATP binding(GO:0032564)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.0 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.0 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.1 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.0 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.0 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.0 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters