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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Mef2b

Z-value: 2.20

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Transcription factors associated with Mef2b

Gene Symbol	Gene ID	Gene Info
Mef2b Ensembl NCBI MGI UniProt	ENSMUSG00000079033.3	Mef2b

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Mef2b	chr8_70152603_70152770	92	0.927902	-0.63	1.8e-01	Click!
Mef2b	chr8_70158443_70158608	5744	0.092534	-0.41	4.2e-01	Click!

Activity of the Mef2b motif across conditions

Conditions sorted by the z-value of the Mef2b motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_14045065_14045224	2.36	1700019J19Rik	RIKEN cDNA 1700019J19 gene	44476	0.14
chr12_109521275_109521426	1.56	Gm34081	predicted gene, 34081	4610	0.06
chr7_140776294_140776445	1.54	Gm29799	predicted gene, 29799	8146	0.09
chrX_38422575_38423072	1.41	Lamp2	lysosomal-associated membrane protein 2	20327	0.15
chr4_131939568_131939730	1.39	Epb41	erythrocyte membrane protein band 4.1	2262	0.18
chr16_41161594_41161767	1.31	Gm26381	predicted gene, 26381	56065	0.15
chr12_104346091_104346278	1.27	Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	7698	0.12
chr3_148981923_148982092	1.20	Gm43573	predicted gene 43573	7145	0.19
chr17_29323966_29324117	1.15	Gm46603	predicted gene, 46603	1492	0.24
chr17_8283278_8283446	1.10	Mpc1	mitochondrial pyruvate carrier 1	400	0.78
chr5_134275072_134275253	1.09	Gtf2i	general transcription factor II I	119	0.94
chr5_86078864_86079015	1.08	Gm24524	predicted gene, 24524	827	0.55
chr13_69029464_69029651	1.06	Gm37122	predicted gene, 37122	12935	0.17
chr3_18131799_18132081	1.02	Gm23686	predicted gene, 23686	45685	0.14
chr9_74889692_74889843	1.02	Onecut1	one cut domain, family member 1	23283	0.14
chr15_97720259_97720503	1.01	Endou	endonuclease, polyU-specific	769	0.57
chr5_75490980_75491142	0.99	Gm24502	predicted gene, 24502	70089	0.09
chr19_40241408_40241559	0.97	Pdlim1	PDZ and LIM domain 1 (elfin)	10678	0.15
chr6_145745302_145745496	0.96	Gm15704	predicted gene 15704	874	0.51
chr7_123405689_123405849	0.95	Lcmt1	leucine carboxyl methyltransferase 1	2411	0.28
chr12_51848413_51848587	0.94	Gm19309	predicted gene, 19309	7879	0.19
chr9_118646031_118646185	0.92	Itga9	integrin alpha 9	39418	0.14
chr7_71872986_71873347	0.92	4930441H08Rik	RIKEN cDNA 4930441H08 gene	36527	0.18
chr16_95439908_95440073	0.90	Erg	ETS transcription factor	19255	0.24
chr16_8843944_8844115	0.90	1810013L24Rik	RIKEN cDNA 1810013L24 gene	12708	0.17
chr16_52071915_52072078	0.90	Cblb	Casitas B-lineage lymphoma b	22343	0.21
chr18_67738121_67738272	0.89	Ptpn2	protein tyrosine phosphatase, non-receptor type 2	13601	0.16
chr14_105803498_105803761	0.89	Gm22406	predicted gene, 22406	13279	0.23
chrX_102187134_102187366	0.88	Rps4x	ribosomal protein S4, X-linked	513	0.68
chr15_88839321_88839531	0.88	Gm23144	predicted gene, 23144	4126	0.16
chr7_116200646_116200810	0.88	Plekha7	pleckstrin homology domain containing, family A member 7	2167	0.34
chr10_80260218_80260407	0.88	Gamt	guanidinoacetate methyltransferase	606	0.42
chr11_110551681_110551869	0.88	Gm11682	predicted gene 11682	7268	0.3
chr6_122826334_122826673	0.87	Foxj2	forkhead box J2	172	0.9
chr7_145111866_145112053	0.86	Gm45181	predicted gene 45181	51037	0.14
chr5_66067292_66067466	0.86	Gm43775	predicted gene 43775	5516	0.14
chr7_145025998_145026178	0.86	Ccnd1	cyclin D1	86163	0.07
chr3_116801818_116802023	0.85	Agl	amylo-1,6-glucosidase, 4-alpha-glucanotransferase	5497	0.14
chr10_34513055_34513206	0.85	Frk	fyn-related kinase	29598	0.2
chr14_100750255_100750445	0.85	Gm23538	predicted gene, 23538	9918	0.23
chr13_101718024_101718189	0.84	Pik3r1	phosphoinositide-3-kinase regulatory subunit 1	16002	0.21
chr8_126807290_126807464	0.83	A630001O12Rik	RIKEN cDNA A630001O12 gene	31856	0.17
chr9_33001470_33001748	0.83	Gm27166	predicted gene 27166	30182	0.17
chr10_25365835_25365986	0.83	Epb41l2	erythrocyte membrane protein band 4.1 like 2	6054	0.21
chr8_80811587_80811961	0.83	Gab1	growth factor receptor bound protein 2-associated protein 1	19110	0.18
chr10_57727739_57727910	0.83	Pkib	protein kinase inhibitor beta, cAMP dependent, testis specific	157	0.96
chr5_98992026_98992185	0.83	Prkg2	protein kinase, cGMP-dependent, type II	25349	0.2
chr9_74327099_74327334	0.81	Gm24141	predicted gene, 24141	35394	0.17
chr9_94615362_94615542	0.81	Gm39404	predicted gene, 39404	23256	0.15
chr2_163685840_163686012	0.81	Gm16316	predicted gene 16316	6353	0.15
chr6_31544399_31544550	0.81	Podxl	podocalyxin-like	19507	0.17
chr4_63229865_63230144	0.81	Col27a1	collagen, type XXVII, alpha 1	4282	0.2
chr15_97462722_97462873	0.81	Gm49506	predicted gene, 49506	95493	0.07
chr15_25940308_25940999	0.81	Retreg1	reticulophagy regulator 1	49	0.98
chr6_116004145_116004296	0.78	Plxnd1	plexin D1	9215	0.16
chr13_93989307_93989458	0.78	Gm47216	predicted gene, 47216	2386	0.28
chr18_46273693_46273856	0.78	Pggt1b	protein geranylgeranyltransferase type I, beta subunit	2155	0.27
chr13_85127287_85127439	0.77	Gm4076	predicted gene 4076	151	0.96
chrX_168832355_168832554	0.77	Arhgap6	Rho GTPase activating protein 6	37355	0.19
chr11_79718866_79719052	0.77	Mir193a	microRNA 193a	6990	0.13
chr1_170623064_170623228	0.77	Gm7299	predicted gene 7299	7775	0.19
chr2_51716857_51717035	0.77	Gm13490	predicted gene 13490	15063	0.23
chr8_47461739_47461890	0.76	Stox2	storkhead box 2	15452	0.16
chr7_80451948_80452113	0.75	Blm	Bloom syndrome, RecQ like helicase	5342	0.14
chr16_48765285_48765461	0.75	Trat1	T cell receptor associated transmembrane adaptor 1	6583	0.2
chr3_72659248_72659399	0.75	Gm37901	predicted gene, 37901	54975	0.16
chr16_95995234_95995402	0.74	Psmg1	proteasome (prosome, macropain) assembly chaperone 1	4358	0.17
chr11_63827631_63827816	0.74	Gm12288	predicted gene 12288	9423	0.22
chr14_117750473_117750636	0.73	Mir6239	microRNA 6239	203293	0.03
chr14_33687746_33687969	0.73	Gm26228	predicted gene, 26228	43362	0.14
chr19_27178438_27178739	0.73	Gm35438	predicted gene, 35438	13421	0.22
chr4_149868069_149868231	0.73	Gm13070	predicted gene 13070	35856	0.09
chr7_19952685_19952933	0.73	Rpl7a-ps8	ribosomal protein L7A, pseudogene 8	974	0.29
chr3_98067419_98067570	0.72	Gm42819	predicted gene 42819	36807	0.13
chr5_121612131_121612311	0.71	Acad12	acyl-Coenzyme A dehydrogenase family, member 12	6592	0.11
chr2_121193827_121193979	0.71	Tubgcp4	tubulin, gamma complex associated protein 4	1956	0.22
chr3_116799201_116799358	0.70	Agl	amylo-1,6-glucosidase, 4-alpha-glucanotransferase	8138	0.13
chr10_84968958_84969109	0.70	Ric8b	RIC8 guanine nucleotide exchange factor B	31640	0.19
chr9_42512108_42512263	0.70	Tbcel	tubulin folding cofactor E-like	4376	0.25
chr5_39219850_39220015	0.70	Gm40293	predicted gene, 40293	87152	0.08
chr12_24615310_24615477	0.70	Gm6969	predicted pseudogene 6969	23617	0.13
chr4_9657208_9657376	0.69	Asph	aspartate-beta-hydroxylase	11794	0.19
chr8_71312491_71313043	0.69	Myo9b	myosin IXb	21050	0.11
chr4_37093076_37093227	0.69	Taf9-ps	TATA-box binding protein associated factor 9, pseudogene	46723	0.17
chr2_158702228_158702379	0.69	Ppp1r16b	protein phosphatase 1, regulatory subunit 16B	6168	0.17
chr12_79598601_79598900	0.68	Rad51b	RAD51 paralog B	271397	0.01
chr11_117574902_117575083	0.68	2900041M22Rik	RIKEN cDNA 2900041M22 gene	36255	0.13
chr2_134872444_134872595	0.68	Gm14036	predicted gene 14036	68570	0.12
chr9_32906282_32906466	0.68	Gm27162	predicted gene 27162	22592	0.19
chr5_75961858_75962064	0.67	Kdr	kinase insert domain protein receptor	16497	0.17
chr18_39855902_39856245	0.67	Gm41708	predicted gene, 41708	73301	0.1
chr7_120151008_120151184	0.66	4930505K13Rik	RIKEN cDNA 4930505K13 gene	5019	0.14
chr17_86302890_86303043	0.66	2010106C02Rik	RIKEN cDNA 2010106C02 gene	15788	0.26
chr4_55042640_55042808	0.65	Zfp462	zinc finger protein 462	31244	0.19
chr4_105261100_105261481	0.65	Plpp3	phospholipid phosphatase 3	103943	0.07
chr4_141324590_141325156	0.65	Epha2	Eph receptor A2	7960	0.1
chr4_95212952_95213103	0.65	Gm12708	predicted gene 12708	19665	0.2
chr11_79453041_79453205	0.65	Gm11199	predicted gene 11199	676	0.61
chr9_32874453_32874604	0.65	Gm37167	predicted gene, 37167	34606	0.16
chr19_29470771_29470965	0.64	Pdcd1lg2	programmed cell death 1 ligand 2	48809	0.1
chr3_18343267_18343427	0.64	Gm43834	predicted gene 43834	44037	0.16
chr5_66745601_66745788	0.64	Limch1	LIM and calponin homology domains 1	133	0.96
chr19_40187264_40187454	0.64	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	26	0.97
chr19_24251878_24252123	0.64	Fxn	frataxin	26171	0.14
chr11_68956181_68956371	0.64	Arhgef15	Rho guanine nucleotide exchange factor (GEF) 15	1202	0.27
chr16_49533485_49533653	0.64	Gm6931	predicted gene 6931	108763	0.06
chr2_20445457_20445703	0.64	Gm13335	predicted gene 13335	12646	0.25
chr2_124741001_124741334	0.63	Gm13994	predicted gene 13994	32512	0.23
chr2_38917032_38917193	0.63	Nr6a1	nuclear receptor subfamily 6, group A, member 1	9105	0.11
chr13_52067119_52067403	0.63	Gm48190	predicted gene, 48190	29381	0.16
chr18_69690243_69690422	0.63	Tcf4	transcription factor 4	7952	0.3
chr3_32668496_32668692	0.63	Actl6a	actin-like 6A	37704	0.11
chr2_5867590_5867753	0.63	Gm13199	predicted gene 13199	4737	0.15
chr10_42082409_42082576	0.63	Tdg-ps2	thymine DNA glycosylase, pseudogene 2	27186	0.19
chr16_10689840_10690031	0.63	Gm15558	predicted gene 15558	6396	0.18
chr18_12295901_12296052	0.63	Ankrd29	ankyrin repeat domain 29	15	0.97
chr17_25067483_25067858	0.62	Tmem204	transmembrane protein 204	10554	0.11
chr8_106718179_106718330	0.62	Tango6	transport and golgi organization 6	35108	0.16
chr13_77045502_77045657	0.62	Slf1	SMC5-SMC6 complex localization factor 1	1818	0.46
chr14_26441614_26441800	0.62	Slmap	sarcolemma associated protein	948	0.52
chr15_59051293_59051444	0.62	Mtss1	MTSS I-BAR domain containing 1	4096	0.26
chr13_81368031_81368195	0.62	Adgrv1	adhesion G protein-coupled receptor V1	16487	0.26
chr11_21225073_21225224	0.62	Gm12041	predicted gene 12041	2507	0.2
chr7_71708283_71708442	0.61	Gm44688	predicted gene 44688	2286	0.26
chr11_77776189_77776355	0.61	Myo18a	myosin XVIIIA	993	0.46
chr17_32935365_32935709	0.61	Cyp4f13	cytochrome P450, family 4, subfamily f, polypeptide 13	4529	0.11
chr2_92424812_92425012	0.61	Cry2	cryptochrome 2 (photolyase-like)	7480	0.11
chr5_124989850_124990034	0.61	Rflna	refilin A	13279	0.18
chr2_145232861_145233023	0.61	Slc24a3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	9669	0.28
chr8_24546361_24546522	0.60	Ido2	indoleamine 2,3-dioxygenase 2	5645	0.19
chr4_142179591_142179879	0.60	Gm13062	predicted gene 13062	867	0.62
chr7_107574446_107574681	0.60	Olfml1	olfactomedin-like 1	6797	0.16
chr7_49393023_49393262	0.60	Nav2	neuron navigator 2	28421	0.19
chr4_130715456_130715632	0.60	Snord85	small nucleolar RNA, C/D box 85	34090	0.11
chr4_129572692_129572886	0.60	Lck	lymphocyte protein tyrosine kinase	852	0.37
chr17_5324481_5324860	0.60	Gm29050	predicted gene 29050	64093	0.11
chr19_34553030_34553190	0.60	Ifit2	interferon-induced protein with tetratricopeptide repeats 2	2400	0.18
chr11_107264737_107265072	0.60	Gm11719	predicted gene 11719	65804	0.07
chr9_65196417_65196590	0.59	Gm25313	predicted gene, 25313	184	0.88
chr7_70972135_70972318	0.59	Gm34783	predicted gene, 34783	59406	0.13
chr17_10040936_10041349	0.59	Gm49809	predicted gene, 49809	93305	0.08
chr9_121435320_121435493	0.59	Trak1	trafficking protein, kinesin binding 1	18890	0.17
chr8_94550090_94550250	0.58	Cpne2	copine II	5344	0.14
chr15_41447157_41447458	0.58	Oxr1	oxidation resistance 1	175	0.97
chr7_90146413_90146603	0.58	Gm45222	predicted gene 45222	560	0.64
chr5_147226195_147226362	0.58	Gm24556	predicted gene, 24556	26025	0.11
chr10_116261258_116261409	0.58	Ptprb	protein tyrosine phosphatase, receptor type, B	14190	0.19
chr17_73067512_73067678	0.58	Gm30420	predicted gene, 30420	38517	0.15
chr4_136466236_136466405	0.58	Luzp1	leucine zipper protein 1	3441	0.19
chr11_88201344_88201495	0.57	Mrps23	mitochondrial ribosomal protein S23	2969	0.23
chr4_102486880_102487056	0.57	Pde4b	phosphodiesterase 4B, cAMP specific	16571	0.29
chr7_38225087_38225250	0.57	Plekhf1	pleckstrin homology domain containing, family F (with FYVE domain) member 1	2848	0.19
chr14_32861212_32861363	0.57	Vstm4	V-set and transmembrane domain containing 4	4531	0.21
chr2_84387502_84387656	0.57	Calcrl	calcitonin receptor-like	12221	0.2
chr5_32446427_32446736	0.57	Ppp1cb	protein phosphatase 1 catalytic subunit beta	12262	0.11
chr19_37501431_37501810	0.57	Exoc6	exocyst complex component 6	19259	0.14
chr2_32969446_32969597	0.56	Snora65	small nucleolar RNA, H/ACA box 65	6230	0.11
chr19_8987926_8988110	0.56	Ahnak	AHNAK nucleoprotein (desmoyokin)	1266	0.26
chr2_71867523_71867680	0.56	Pdk1	pyruvate dehydrogenase kinase, isoenzyme 1	5623	0.2
chr1_68501656_68501817	0.55	Gm19335	predicted gene, 19335	91950	0.08
chr14_26162589_26162740	0.55	Gm2274	predicted gene 2274	6628	0.13
chr5_32328252_32328418	0.55	Gm15615	predicted gene 15615	16216	0.14
chr2_134825894_134826247	0.55	Gm14036	predicted gene 14036	22121	0.2
chr13_9445564_9445785	0.55	Gm48871	predicted gene, 48871	226	0.93
chr16_89830199_89830569	0.55	Tiam1	T cell lymphoma invasion and metastasis 1	7491	0.3
chr4_52815809_52815985	0.55	Olfr275	olfactory receptor 275	1293	0.37
chr1_21829923_21830095	0.55	Gm38243	predicted gene, 38243	10505	0.24
chr14_25883204_25883355	0.55	Anxa11os	annexin A11, opposite strand	13013	0.12
chr18_11327208_11327359	0.55	Gata6	GATA binding protein 6	268236	0.01
chr1_35759768_35759937	0.55	Gm25634	predicted gene, 25634	1750	0.42
chr19_41837838_41838023	0.55	Frat1	frequently rearranged in advanced T cell lymphomas	7960	0.14
chr13_99794055_99794213	0.55	Gm24471	predicted gene, 24471	101605	0.06
chr1_13384478_13384660	0.54	Gm29570	predicted gene 29570	8499	0.13
chr10_84774729_84774903	0.54	Rfx4	regulatory factor X, 4 (influences HLA class II expression)	12578	0.21
chr12_85825843_85826036	0.54	Ttll5	tubulin tyrosine ligase-like family, member 5	545	0.68
chr1_61143547_61143729	0.54	Gm11590	predicted gene 11590	19634	0.19
chr3_101804015_101804166	0.54	Mab21l3	mab-21-like 3	32133	0.17
chr16_23976333_23976484	0.53	Bcl6	B cell leukemia/lymphoma 6	4028	0.2
chr13_101316368_101316712	0.53	Gm2534	predicted gene 2534	32212	0.18
chr1_176823956_176824133	0.53	Sdccag8	serologically defined colon cancer antigen 8	9384	0.11
chr11_87423004_87423313	0.53	Rnu1a1	U1a1 small nuclear RNA	291	0.79
chr5_28060446_28060778	0.53	Gm26608	predicted gene, 26608	5153	0.18
chr4_67124974_67125163	0.52	Gm11403	predicted gene 11403	40411	0.23
chr5_36620793_36620967	0.52	D5Ertd579e	DNA segment, Chr 5, ERATO Doi 579, expressed	375	0.78
chr19_21274268_21274440	0.52	Zfand5	zinc finger, AN1-type domain 5	1108	0.47
chr7_132786130_132786291	0.52	Fam53b	family with sequence similarity 53, member B	709	0.69
chr9_7858246_7858397	0.52	Birc3	baculoviral IAP repeat-containing 3	2005	0.3
chr10_68168093_68168385	0.52	Arid5b	AT rich interactive domain 5B (MRF1-like)	31613	0.21
chr4_65947314_65947465	0.52	Trim32	tripartite motif-containing 32	342140	0.01
chr18_34868711_34868905	0.52	Egr1	early growth response 1	7601	0.14
chr1_131090290_131090446	0.52	Gm37084	predicted gene, 37084	1781	0.26
chr15_101266552_101266884	0.52	Nr4a1	nuclear receptor subfamily 4, group A, member 1	128	0.93
chr13_44409176_44409378	0.52	Gm33958	predicted gene, 33958	18160	0.15
chr7_71411542_71411776	0.52	Gm29328	predicted gene 29328	41326	0.15
chr7_29179325_29179528	0.52	Psmd8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	405	0.65
chr10_68842447_68842629	0.52	1700048P04Rik	RIKEN cDNA 1700048P04 gene	61962	0.13
chr5_143492763_143492920	0.51	Daglb	diacylglycerol lipase, beta	6163	0.13
chr10_99314465_99314820	0.51	B530045E10Rik	RIKEN cDNA B530045E10 gene	15476	0.14
chr1_67201067_67201218	0.51	Gm15668	predicted gene 15668	48058	0.14
chr8_33709174_33709335	0.51	Gm24727	predicted gene, 24727	17453	0.12

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Mef2b

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.2	0.5	GO:1902988	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.1	0.4	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.1	0.5	GO:0090427	activation of meiosis(GO:0090427)
0.1	0.5	GO:0035864	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.1	0.9	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	0.3	GO:0045218	zonula adherens maintenance(GO:0045218)
0.1	0.3	GO:0006481	C-terminal protein methylation(GO:0006481)
0.1	0.3	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.1	0.3	GO:0071288	cellular response to mercury ion(GO:0071288)
0.1	0.3	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1	0.4	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.4	GO:0071376	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1	0.3	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1	0.3	GO:1903969	regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.1	0.3	GO:0021564	vagus nerve development(GO:0021564)
0.1	0.3	GO:0050883	musculoskeletal movement, spinal reflex action(GO:0050883)
0.1	0.6	GO:0048194	Golgi vesicle budding(GO:0048194)
0.1	0.4	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.1	0.4	GO:0003105	negative regulation of glomerular filtration(GO:0003105)
0.1	0.4	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.1	0.1	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.1	0.2	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.1	0.2	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.1	0.3	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.1	0.2	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	1.0	GO:0014733	regulation of skeletal muscle adaptation(GO:0014733)
0.1	0.3	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1	0.3	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.1	0.1	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.1	0.2	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.1	0.5	GO:0018095	protein polyglutamylation(GO:0018095)
0.1	0.2	GO:0019287	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1	0.3	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.1	0.2	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.1	0.3	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.1	0.1	GO:0003162	atrioventricular node development(GO:0003162)
0.1	0.2	GO:0001692	histamine metabolic process(GO:0001692)
0.1	0.2	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.1	0.2	GO:1903977	positive regulation of glial cell migration(GO:1903977)
0.0	0.1	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.1	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.1	GO:0034436	glycoprotein transport(GO:0034436)
0.0	0.0	GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0	0.2	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.1	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.0	GO:0046084	adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.2	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.5	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	0.5	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.3	GO:1901841	regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0	0.2	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.0	0.1	GO:1904017	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.1	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.2	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.1	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0	0.2	GO:0014022	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.3	GO:0060613	fat pad development(GO:0060613)
0.0	0.1	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.1	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.2	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.0	0.2	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	1.1	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.0	GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.0	0.1	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.0	0.1	GO:0034197	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.1	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.0	0.3	GO:0097341	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0	0.1	GO:0048320	axial mesoderm formation(GO:0048320)
0.0	0.1	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0	0.1	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0	0.1	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0	0.1	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.1	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.0	0.2	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.1	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.3	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.1	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.1	GO:0072203	cell proliferation involved in metanephros development(GO:0072203)
0.0	0.1	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.0	0.1	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.1	GO:1905065	positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.0	0.1	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.0	0.0	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.1	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.1	GO:0046881	positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.1	GO:0008355	olfactory learning(GO:0008355)
0.0	0.1	GO:0006533	aspartate catabolic process(GO:0006533)
0.0	0.1	GO:0051890	regulation of cardioblast differentiation(GO:0051890)
0.0	0.0	GO:0021888	cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) sensory neuron axon guidance(GO:0097374) facioacoustic ganglion development(GO:1903375)
0.0	0.1	GO:1900377	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0	0.1	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.2	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.1	GO:0002249	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0	0.2	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.1	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.0	0.1	GO:1904970	brush border assembly(GO:1904970)
0.0	0.2	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0061577	calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.0	0.4	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0	0.1	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.2	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.1	GO:1903626	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0	0.2	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.0	0.2	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.0	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.2	GO:0061042	vascular wound healing(GO:0061042)
0.0	0.1	GO:0014042	positive regulation of neuron maturation(GO:0014042)
0.0	0.2	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.2	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.6	GO:0048745	smooth muscle tissue development(GO:0048745)
0.0	0.1	GO:0002568	somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0	0.2	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0	0.0	GO:0061346	non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0	0.1	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0	0.1	GO:0060058	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0030578	PML body organization(GO:0030578)
0.0	0.1	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.1	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	0.1	GO:0072223	metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.0	0.1	GO:0051594	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0090365	regulation of mRNA modification(GO:0090365)
0.0	0.1	GO:0002636	positive regulation of germinal center formation(GO:0002636)
0.0	0.1	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	0.0	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.1	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.0	0.0	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0	0.1	GO:0015755	fructose transport(GO:0015755)
0.0	0.1	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
0.0	0.2	GO:0070474	positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0	0.0	GO:1903416	response to glycoside(GO:1903416)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0002666	positive regulation of T cell tolerance induction(GO:0002666)
0.0	0.1	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.0	0.0	GO:0021764	amygdala development(GO:0021764)
0.0	0.1	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.1	GO:0045915	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0	0.1	GO:0003289	septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
0.0	0.0	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0	0.1	GO:0019230	proprioception(GO:0019230)
0.0	0.1	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.0	0.0	GO:0009756	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.1	GO:1901894	regulation of calcium-transporting ATPase activity(GO:1901894)
0.0	0.1	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0	0.1	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373)
0.0	0.2	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.0	GO:0002645	positive regulation of tolerance induction(GO:0002645)
0.0	0.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.1	GO:0015817	histidine transport(GO:0015817)
0.0	0.1	GO:0002071	glandular epithelial cell maturation(GO:0002071)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.5	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.0	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.1	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.0	0.1	GO:0060178	regulation of exocyst localization(GO:0060178)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.2	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.2	GO:1902400	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.0	0.1	GO:1904251	regulation of bile acid metabolic process(GO:1904251)
0.0	0.1	GO:0009597	detection of virus(GO:0009597)
0.0	0.1	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
0.0	0.0	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.1	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0	0.1	GO:0035878	nail development(GO:0035878)
0.0	0.1	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.2	GO:1901409	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.0	GO:0046103	inosine biosynthetic process(GO:0046103)
0.0	0.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.0	GO:0019660	fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0	0.1	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.0	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0	0.1	GO:0032308	positive regulation of prostaglandin secretion(GO:0032308)
0.0	0.0	GO:0055099	response to high density lipoprotein particle(GO:0055099)
0.0	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.1	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.0	0.0	GO:0071866	regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
0.0	0.3	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.1	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0	0.1	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.1	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.1	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0	0.0	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.2	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:1904322	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0	0.1	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.1	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0	0.1	GO:0009436	glyoxylate catabolic process(GO:0009436)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	0.1	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.0	0.1	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0	0.1	GO:1900044	regulation of protein K63-linked ubiquitination(GO:1900044)
0.0	0.0	GO:0070343	white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.0	0.1	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.0	0.1	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0	0.1	GO:0030836	positive regulation of actin filament depolymerization(GO:0030836)
0.0	0.0	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.0	GO:1904751	regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.0	0.1	GO:0002934	desmosome organization(GO:0002934)
0.0	0.0	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.0	0.0	GO:0070858	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0	0.1	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0	0.0	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0	0.0	GO:0010847	regulation of chromatin assembly(GO:0010847)
0.0	0.1	GO:0070166	enamel mineralization(GO:0070166)
0.0	0.0	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.0	GO:0009804	coumarin metabolic process(GO:0009804)
0.0	0.1	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.0	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0	0.0	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725)
0.0	0.0	GO:0046208	spermine catabolic process(GO:0046208)
0.0	0.0	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0	0.0	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.0	GO:0009233	menaquinone metabolic process(GO:0009233)
0.0	0.1	GO:0072592	oxygen metabolic process(GO:0072592)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.0	0.1	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.0	GO:0052203	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.0	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0	0.1	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.1	GO:0072602	interleukin-4 secretion(GO:0072602)
0.0	0.1	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.0	0.0	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.0	0.1	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0	0.0	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.1	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.0	GO:1902369	negative regulation of RNA catabolic process(GO:1902369)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.3	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.0	GO:0032278	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of luteinizing hormone secretion(GO:0033686)
0.0	0.1	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.0	0.1	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.1	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.1	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.0	0.0	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.0	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.0	0.0	GO:0042374	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0	0.0	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.0	GO:0065001	specification of axis polarity(GO:0065001)
0.0	0.0	GO:1903599	positive regulation of mitophagy(GO:1903599)
0.0	0.1	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.0	GO:0035795	negative regulation of mitochondrial membrane permeability(GO:0035795)
0.0	0.1	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.1	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0	0.1	GO:0044351	macropinocytosis(GO:0044351)
0.0	0.4	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	0.1	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
0.0	0.1	GO:0032596	protein transport into membrane raft(GO:0032596)
0.0	0.0	GO:0090069	regulation of ribosome biogenesis(GO:0090069) negative regulation of ribosome biogenesis(GO:0090071)
0.0	0.0	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.0	0.0	GO:0061198	fungiform papilla formation(GO:0061198)
0.0	0.0	GO:1900736	regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.0	0.1	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.0	GO:0030916	otic vesicle formation(GO:0030916)
0.0	0.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.1	GO:0045046	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0	0.0	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.0	0.0	GO:0032377	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0	0.1	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.0	GO:0015884	folic acid transport(GO:0015884)
0.0	0.0	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0	0.0	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0	0.1	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.0	0.0	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.0	GO:0060066	oviduct development(GO:0060066)
0.0	0.0	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.1	GO:0033182	regulation of histone ubiquitination(GO:0033182)
0.0	0.0	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.0	GO:0000087	mitotic M phase(GO:0000087)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.0	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.0	0.0	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
0.0	0.0	GO:0035995	detection of muscle stretch(GO:0035995)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.0	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.0	0.0	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.1	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0	0.0	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.0	0.0	GO:0009177	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0043305	negative regulation of mast cell degranulation(GO:0043305)
0.0	0.1	GO:1903358	regulation of Golgi organization(GO:1903358)
0.0	0.0	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.1	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.0	GO:0033602	negative regulation of dopamine secretion(GO:0033602)
0.0	0.1	GO:0098764	meiotic prophase I(GO:0007128) prophase(GO:0051324) meiotic cell cycle phase(GO:0098762) meiosis I cell cycle phase(GO:0098764)
0.0	0.0	GO:2000619	negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0	0.0	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.0	0.1	GO:0098739	import across plasma membrane(GO:0098739)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0097418	neurofibrillary tangle(GO:0097418)
0.1	0.3	GO:0032127	dense core granule membrane(GO:0032127)
0.1	0.3	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.4	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	0.3	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.1	0.1	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.1	0.2	GO:1990696	USH2 complex(GO:1990696)
0.1	0.4	GO:0005915	zonula adherens(GO:0005915)
0.1	0.3	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.2	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.2	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.4	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.2	GO:0000923	equatorial microtubule organizing center(GO:0000923)
0.0	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.8	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0046691	intracellular canaliculus(GO:0046691)
0.0	0.2	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0031523	Myb complex(GO:0031523)
0.0	0.1	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.1	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.2	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.2	GO:0060091	kinocilium(GO:0060091)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0005775	vacuolar lumen(GO:0005775)
0.0	0.4	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0	0.3	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.1	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.1	GO:0097255	R2TP complex(GO:0097255)
0.0	0.0	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.0	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.1	GO:0002081	outer acrosomal membrane(GO:0002081)
0.0	0.1	GO:0000938	GARP complex(GO:0000938)
0.0	0.1	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.4	GO:0032809	neuronal cell body membrane(GO:0032809)
0.0	0.0	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:0071006	U2-type catalytic step 1 spliceosome(GO:0071006)
0.0	0.1	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	0.2	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.2	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.2	GO:0001741	XY body(GO:0001741)
0.0	0.3	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.6	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	0.1	GO:0031415	NatA complex(GO:0031415)
0.0	0.0	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.0	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.0	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520)
0.0	0.5	GO:0005844	polysome(GO:0005844)
0.0	0.1	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.1	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.0	GO:0000811	GINS complex(GO:0000811)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.1	0.4	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.9	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.3	GO:0015182	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.1	0.3	GO:0042731	PH domain binding(GO:0042731)
0.1	0.3	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1	0.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.4	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.2	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.1	GO:0005290	L-histidine transmembrane transporter activity(GO:0005290)
0.1	0.2	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.1	0.4	GO:0018654	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.1	0.2	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.2	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1	0.2	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1	0.4	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.4	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.0	0.3	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.3	GO:1990459	transferrin receptor binding(GO:1990459)
0.0	0.5	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.2	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.2	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.3	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.7	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0033142	progesterone receptor binding(GO:0033142)
0.0	0.1	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0	0.4	GO:0005536	glucose binding(GO:0005536)
0.0	0.2	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0	0.1	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0	0.2	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.3	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.2	GO:0050051	leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.0	0.3	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.5	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	0.3	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.2	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.7	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0070905	serine binding(GO:0070905)
0.0	0.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.0	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0031686	A1 adenosine receptor binding(GO:0031686)
0.0	0.0	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.1	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.3	GO:0071949	FAD binding(GO:0071949)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.1	GO:0008251	tRNA-specific adenosine deaminase activity(GO:0008251)
0.0	0.1	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.1	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.0	GO:0045503	dynein light chain binding(GO:0045503)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.1	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0	0.1	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.2	GO:0030553	cGMP binding(GO:0030553)
0.0	0.1	GO:0097108	hedgehog family protein binding(GO:0097108)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.5	GO:0043531	ADP binding(GO:0043531)
0.0	0.1	GO:0004556	alpha-amylase activity(GO:0004556)
0.0	0.1	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.5	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.2	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.2	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.0	GO:0070698	type I activin receptor binding(GO:0070698)
0.0	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.2	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.1	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.2	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.4	GO:0030507	spectrin binding(GO:0030507)
0.0	0.0	GO:0031433	telethonin binding(GO:0031433)
0.0	0.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.0	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.0	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	0.0	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.0	0.2	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.0	0.1	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.0	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	0.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.2	GO:0030552	cAMP binding(GO:0030552)
0.0	0.0	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.0	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.0	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.1	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.5	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.1	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.0	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.6	GO:0008392	arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.0	0.1	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:1990932	5.8S rRNA binding(GO:1990932)
0.0	0.0	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.0	0.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.0	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0034847	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.2	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.0	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0	0.0	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.0	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.0	0.0	GO:0019145	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0	0.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.0	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.0	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.0	0.1	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.0	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.1	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.0	0.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.0	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.0	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	0.0	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.0	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.0	0.0	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	0.1	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.1	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	1.4	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.4	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.0	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.5	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.3	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.4	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.2	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.3	ST ADRENERGIC	Adrenergic Pathway
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.5	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.5	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.5	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.1	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.2	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.1	PID S1P S1P2 PATHWAY	S1P2 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.1	0.2	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.0	0.4	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.5	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.2	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.0	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.3	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.7	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.3	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.3	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.1	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.3	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.0	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.1	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.4	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels