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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Mef2d_Mef2a

Z-value: 1.79

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Transcription factors associated with Mef2d_Mef2a

Gene Symbol	Gene ID	Gene Info
Mef2d Ensembl NCBI MGI UniProt	ENSMUSG00000001419.11	myocyte enhancer factor 2D
Mef2a Ensembl NCBI MGI UniProt	ENSMUSG00000030557.10	myocyte enhancer factor 2A

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr7_67259960_67260114	Mef2a	6125	0.173381	-0.92	8.6e-03	Click!
chr7_67380279_67380446	Mef2a	7504	0.193780	0.88	1.9e-02	Click!
chr7_67372813_67372982	Mef2a	39	0.971167	0.88	2.0e-02	Click!
chr7_67342152_67342326	Mef2a	25274	0.161209	0.80	5.4e-02	Click!
chr7_67373368_67373531	Mef2a	591	0.719494	0.80	5.5e-02	Click!
chr3_88138374_88138539	Mef2d	3916	0.127214	0.93	6.4e-03	Click!
chr3_88141898_88142422	Mef2d	212	0.883224	0.91	1.2e-02	Click!
chr3_88131172_88131331	Mef2d	11121	0.101921	0.90	1.4e-02	Click!
chr3_88163993_88164144	Mef2d	1108	0.314058	0.79	6.4e-02	Click!
chr3_88137106_88137267	Mef2d	5186	0.116151	0.77	7.6e-02	Click!

Activity of the Mef2d_Mef2a motif across conditions

Conditions sorted by the z-value of the Mef2d_Mef2a motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_24615310_24615477	2.80	Gm6969	predicted pseudogene 6969	23617	0.13
chr4_149868069_149868231	2.30	Gm13070	predicted gene 13070	35856	0.09
chr10_84803969_84804150	2.14	Gm24226	predicted gene, 24226	7124	0.23
chr5_139343215_139343377	1.80	Cox19	cytochrome c oxidase assembly protein 19	1829	0.23
chr8_11149308_11149679	1.62	Gm44717	predicted gene 44717	247	0.91
chr4_129921550_129921737	1.60	Spocd1	SPOC domain containing 1	7606	0.12
chr6_122826334_122826673	1.58	Foxj2	forkhead box J2	172	0.9
chr2_163411853_163412159	1.46	Oser1	oxidative stress responsive serine rich 1	341	0.82
chr7_38225087_38225250	1.44	Plekhf1	pleckstrin homology domain containing, family F (with FYVE domain) member 1	2848	0.19
chr11_117574902_117575083	1.42	2900041M22Rik	RIKEN cDNA 2900041M22 gene	36255	0.13
chr16_52071915_52072078	1.42	Cblb	Casitas B-lineage lymphoma b	22343	0.21
chr6_145745302_145745496	1.36	Gm15704	predicted gene 15704	874	0.51
chr2_157479977_157480148	1.35	Src	Rous sarcoma oncogene	22977	0.13
chr3_153907883_153908055	1.34	Msh4	mutS homolog 4	1831	0.16
chr1_125458645_125458813	1.32	Gm28706	predicted gene 28706	14162	0.23
chr17_23674735_23674886	1.30	Thoc6	THO complex 6	928	0.22
chr15_89415369_89415535	1.29	Syce3	synaptonemal complex central element protein 3	4949	0.08
chr4_141324590_141325156	1.28	Epha2	Eph receptor A2	7960	0.1
chr10_68168093_68168385	1.28	Arid5b	AT rich interactive domain 5B (MRF1-like)	31613	0.21
chr16_36036164_36036487	1.24	Wdr5b	WD repeat domain 5B	4865	0.12
chr15_89425967_89426167	1.22	Cpt1b	carnitine palmitoyltransferase 1b, muscle	204	0.8
chr7_49386733_49387219	1.21	Nav2	neuron navigator 2	22255	0.21
chr11_77800957_77801108	1.21	Myo18a	myosin XVIIIA	266	0.89
chr11_104270995_104271175	1.19	Mapt	microtubule-associated protein tau	11296	0.14
chr17_51367620_51367791	1.19	C330011F03Rik	RIKEN cDNA C330011F03 gene	68133	0.12
chr17_74544995_74545158	1.18	Birc6	baculoviral IAP repeat-containing 6	1122	0.48
chr10_25365835_25365986	1.16	Epb41l2	erythrocyte membrane protein band 4.1 like 2	6054	0.21
chr2_45514799_45515150	1.15	Gm13478	predicted gene 13478	132217	0.05
chr4_37093076_37093227	1.13	Taf9-ps	TATA-box binding protein associated factor 9, pseudogene	46723	0.17
chr13_74363963_74364122	1.12	Lrrc14b	leucine rich repeat containing 14B	37	0.94
chr2_128338724_128338875	1.11	Morrbid	myeloid RNA regulator of BCL2L11 induced cell death	4931	0.27
chr9_70019001_70019168	1.11	Gtf2a2	general transcription factor II A, 2	36	0.97
chr10_59525038_59525344	1.10	Mcu	mitochondrial calcium uniporter	67031	0.1
chr19_36553654_36554112	1.10	Hectd2	HECT domain E3 ubiquitin protein ligase 2	756	0.72
chr10_95583008_95583178	1.08	Nudt4	nudix (nucleoside diphosphate linked moiety X)-type motif 4	18947	0.12
chr10_61366025_61366176	1.08	Gm48077	predicted gene, 48077	6434	0.13
chr1_176823956_176824133	1.06	Sdccag8	serologically defined colon cancer antigen 8	9384	0.11
chr13_30235169_30235331	1.05	Mboat1	membrane bound O-acyltransferase domain containing 1	3397	0.27
chr4_130715456_130715632	1.04	Snord85	small nucleolar RNA, C/D box 85	34090	0.11
chr14_21053182_21053494	1.04	Adk	adenosine kinase	621	0.53
chr11_60845525_60845703	1.03	Dhrs7b	dehydrogenase/reductase (SDR family) member 7B	14935	0.09
chr14_55080666_55080850	1.02	Zfhx2	zinc finger homeobox 2	306	0.77
chr16_13189863_13190030	1.02	Ercc4	excision repair cross-complementing rodent repair deficiency, complementation group 4	57555	0.13
chr3_95439810_95439972	1.00	Arnt	aryl hydrocarbon receptor nuclear translocator	5372	0.1
chr6_116004145_116004296	0.99	Plxnd1	plexin D1	9215	0.16
chr11_94327853_94328021	0.98	Ankrd40	ankyrin repeat domain 40	64	0.96
chr2_158702228_158702379	0.97	Ppp1r16b	protein phosphatase 1, regulatory subunit 16B	6168	0.17
chr2_79996611_79996783	0.96	Pde1a	phosphodiesterase 1A, calmodulin-dependent	42332	0.2
chr14_100750255_100750445	0.96	Gm23538	predicted gene, 23538	9918	0.23
chr17_47759779_47759961	0.96	Tfeb	transcription factor EB	695	0.57
chr9_32874453_32874604	0.95	Gm37167	predicted gene, 37167	34606	0.16
chr7_84112155_84112947	0.94	Cemip	cell migration inducing protein, hyaluronan binding	26049	0.14
chr10_8912248_8912575	0.93	Gm48727	predicted gene, 48727	8430	0.16
chr14_47192468_47192644	0.92	Gch1	GTP cyclohydrolase 1	3143	0.13
chr18_42089003_42089154	0.91	Sh3rf2	SH3 domain containing ring finger 2	35368	0.15
chr4_54874330_54874547	0.91	Gm12479	predicted gene 12479	21310	0.23
chr14_27368728_27368894	0.91	Arhgef3	Rho guanine nucleotide exchange factor (GEF) 3	7422	0.2
chr10_42491293_42491460	0.91	Snx3	sorting nexin 3	10654	0.18
chr13_23762358_23762521	0.89	H3c1	H3 clustered histone 1	53	0.86
chr2_163685840_163686012	0.89	Gm16316	predicted gene 16316	6353	0.15
chr3_116799201_116799358	0.89	Agl	amylo-1,6-glucosidase, 4-alpha-glucanotransferase	8138	0.13
chr5_64345854_64346014	0.88	Gm43838	predicted gene 43838	14580	0.14
chr13_69029464_69029651	0.87	Gm37122	predicted gene, 37122	12935	0.17
chr7_90146413_90146603	0.87	Gm45222	predicted gene 45222	560	0.64
chr13_22034369_22034538	0.86	Gm44390	predicted gene, 44390	711	0.26
chr10_68218812_68220021	0.86	Arid5b	AT rich interactive domain 5B (MRF1-like)	59305	0.13
chr12_109521275_109521426	0.85	Gm34081	predicted gene, 34081	4610	0.06
chr6_88627459_88627634	0.85	Kbtbd12	kelch repeat and BTB (POZ) domain containing 12	98	0.97
chr4_102734911_102735096	0.85	Gm24869	predicted gene, 24869	1809	0.4
chr13_52067119_52067403	0.84	Gm48190	predicted gene, 48190	29381	0.16
chr5_66067292_66067466	0.84	Gm43775	predicted gene 43775	5516	0.14
chr15_100066644_100066946	0.84	Gm49474	predicted gene, 49474	24962	0.12
chr5_32328252_32328418	0.84	Gm15615	predicted gene 15615	16216	0.14
chr10_84774729_84774903	0.84	Rfx4	regulatory factor X, 4 (influences HLA class II expression)	12578	0.21
chr9_108806919_108807090	0.84	Nckipsd	NCK interacting protein with SH3 domain	1364	0.23
chr5_64598681_64598889	0.84	Gm3716	predicted gene 3716	4375	0.14
chr2_20445457_20445703	0.83	Gm13335	predicted gene 13335	12646	0.25
chr1_170623064_170623228	0.83	Gm7299	predicted gene 7299	7775	0.19
chr2_134872444_134872595	0.83	Gm14036	predicted gene 14036	68570	0.12
chr17_27851204_27851366	0.83	Uhrf1bp1	UHRF1 (ICBP90) binding protein 1	5156	0.12
chr5_121612131_121612311	0.83	Acad12	acyl-Coenzyme A dehydrogenase family, member 12	6592	0.11
chr11_68655654_68655805	0.83	Myh10	myosin, heavy polypeptide 10, non-muscle	35830	0.14
chr1_173802690_173802855	0.80	Ifi203-ps	interferon activated gene 203, pseudogene	4502	0.15
chr10_68842447_68842629	0.80	1700048P04Rik	RIKEN cDNA 1700048P04 gene	61962	0.13
chr6_55336290_55336455	0.80	Aqp1	aquaporin 1	60	0.97
chr11_6442655_6442932	0.80	H2az2	H2A.Z histone variant 2	1559	0.19
chr15_25940308_25940999	0.80	Retreg1	reticulophagy regulator 1	49	0.98
chr11_110551681_110551869	0.79	Gm11682	predicted gene 11682	7268	0.3
chr15_97720259_97720503	0.79	Endou	endonuclease, polyU-specific	769	0.57
chr1_170866990_170867151	0.77	Atf6	activating transcription factor 6	701	0.47
chr1_155059625_155059797	0.76	Gm29282	predicted gene 29282	2532	0.24
chrX_38422575_38423072	0.75	Lamp2	lysosomal-associated membrane protein 2	20327	0.15
chr4_35134987_35135178	0.75	Ifnk	interferon kappa	16974	0.18
chr1_105908084_105908345	0.75	Gm37779	predicted gene, 37779	17202	0.16
chr2_114776001_114776450	0.74	Gm13975	predicted gene 13975	68113	0.11
chr2_170184030_170184313	0.74	Zfp217	zinc finger protein 217	36068	0.2
chr1_72226614_72226900	0.73	Gm25360	predicted gene, 25360	517	0.69
chr17_86710487_86710973	0.73	Gm22235	predicted gene, 22235	7323	0.19
chr11_75172316_75172519	0.73	1700016P03Rik	RIKEN cDNA 1700016P03 gene	143	0.85
chr12_4392126_4392277	0.73	Ncoa1	nuclear receptor coactivator 1	24595	0.16
chr18_34868711_34868905	0.73	Egr1	early growth response 1	7601	0.14
chr6_140750725_140750913	0.73	Rpl38-ps2	ribosomal protein L38, pseudogene 2	3647	0.24
chr6_125527760_125527927	0.72	Vwf	Von Willebrand factor	18931	0.15
chr14_62509443_62509815	0.72	Gm6076	predicted gene 6076	5666	0.14
chr8_11183553_11183933	0.72	Gm15418	predicted gene 15418	4012	0.2
chr15_99724495_99724669	0.70	Gm16537	predicted gene 16537	108	0.88
chr4_95378542_95378947	0.70	Gm29064	predicted gene 29064	24046	0.21
chr15_25269758_25269937	0.69	9230109A22Rik	RIKEN cDNA 9230109A22 gene	31017	0.15
chr7_73579464_73579639	0.69	1810026B05Rik	RIKEN cDNA 1810026B05 gene	21156	0.1
chr7_123405689_123405849	0.68	Lcmt1	leucine carboxyl methyltransferase 1	2411	0.28
chr5_74311717_74311868	0.68	Gm15981	predicted gene 15981	5242	0.18
chr15_81898957_81899245	0.67	Aco2	aconitase 2, mitochondrial	3795	0.11
chr11_31874160_31874327	0.67	Cpeb4	cytoplasmic polyadenylation element binding protein 4	968	0.59
chr14_65968492_65968660	0.67	Clu	clusterin	66	0.97
chr15_41447157_41447458	0.65	Oxr1	oxidation resistance 1	175	0.97
chr7_67372813_67372982	0.65	Mef2a	myocyte enhancer factor 2A	39	0.97
chr5_7955475_7955629	0.64	Gm30835	predicted gene, 30835	4794	0.18
chr15_88839321_88839531	0.64	Gm23144	predicted gene, 23144	4126	0.16
chr16_45644092_45644274	0.63	Gm49585	predicted gene, 49585	1826	0.28
chr6_99485259_99485416	0.63	Gm22328	predicted gene, 22328	635	0.75
chr14_25488157_25488314	0.63	Gm47921	predicted gene, 47921	8181	0.14
chr5_66745601_66745788	0.63	Limch1	LIM and calponin homology domains 1	133	0.96
chr9_110150354_110150580	0.62	Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	18430	0.13
chr17_73970400_73970733	0.62	Xdh	xanthine dehydrogenase	20370	0.15
chr15_97821321_97821590	0.62	Hdac7	histone deacetylase 7	6592	0.16
chr4_141367578_141367729	0.62	Fam131c	family with sequence similarity 131, member C	567	0.57
chr1_184330776_184331172	0.62	Gm37223	predicted gene, 37223	27355	0.2
chr5_96162930_96163161	0.61	Cnot6l	CCR4-NOT transcription complex, subunit 6-like	1055	0.55
chr10_17408358_17408556	0.61	Gm47760	predicted gene, 47760	75580	0.09
chr9_94645734_94645907	0.61	Gm24178	predicted gene, 24178	1801	0.32
chr7_139364341_139364502	0.61	Inpp5a	inositol polyphosphate-5-phosphatase A	24688	0.19
chr15_77251769_77252001	0.61	Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	6299	0.17
chr4_63986335_63986506	0.60	8030451A03Rik	RIKEN cDNA 8030451A03 gene	6460	0.23
chr1_64121612_64121922	0.60	Klf7	Kruppel-like factor 7 (ubiquitous)	276	0.92
chr3_95277083_95277370	0.60	Mindy1	MINDY lysine 48 deubiquitinase 1	4119	0.09
chr5_86078864_86079015	0.60	Gm24524	predicted gene, 24524	827	0.55
chrX_12252686_12252938	0.60	Gm14521	predicted gene 14521	72745	0.1
chr7_132714300_132714476	0.60	Gm15582	predicted gene 15582	54504	0.1
chr16_70329542_70329827	0.59	Gbe1	glucan (1,4-alpha-), branching enzyme 1	15550	0.24
chr10_78255674_78256028	0.59	Gm30122	predicted gene, 30122	260	0.84
chr2_35337487_35337654	0.59	Stom	stomatin	594	0.64
chr11_100837297_100837448	0.59	Stat5b	signal transducer and activator of transcription 5B	13166	0.12
chr3_146778569_146778743	0.58	Prkacb	protein kinase, cAMP dependent, catalytic, beta	2760	0.25
chr12_32856913_32857188	0.58	Gm47948	predicted gene, 47948	21255	0.15
chr7_80451948_80452113	0.58	Blm	Bloom syndrome, RecQ like helicase	5342	0.14
chr1_13305287_13305442	0.57	Ncoa2	nuclear receptor coactivator 2	5642	0.13
chr9_68940674_68941110	0.57	Rora	RAR-related orphan receptor alpha	254649	0.02
chr1_51515055_51515206	0.57	Gm17767	predicted gene, 17767	2801	0.26
chr7_139273450_139273656	0.57	Pwwp2b	PWWP domain containing 2B	7754	0.16
chr10_71282973_71283124	0.56	Ube2d1	ubiquitin-conjugating enzyme E2D 1	2170	0.21
chrX_103732986_103733363	0.56	Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	1015	0.43
chr2_84387502_84387656	0.55	Calcrl	calcitonin receptor-like	12221	0.2
chr4_10964921_10965302	0.55	Rps11-ps3	ribosomal protein S11, pseudogene 3	18503	0.16
chr8_126589572_126589953	0.55	Irf2bp2	interferon regulatory factor 2 binding protein 2	4224	0.26
chr1_131090290_131090446	0.55	Gm37084	predicted gene, 37084	1781	0.26
chr17_13656719_13656900	0.54	2700054A10Rik	RIKEN cDNA 2700054A10 gene	12082	0.15
chr10_117940988_117941175	0.54	4933411E08Rik	RIKEN cDNA 4933411E08 gene	15622	0.18
chr2_115757775_115757975	0.54	Meis2	Meis homeobox 2	110992	0.06
chr12_3781435_3781588	0.54	Dtnb	dystrobrevin, beta	1963	0.3
chr6_86585249_86585412	0.54	Gm44369	predicted gene, 44369	6100	0.12
chr17_10040936_10041349	0.53	Gm49809	predicted gene, 49809	93305	0.08
chr4_109769208_109769368	0.53	Gm12808	predicted gene 12808	14471	0.23
chr3_9817209_9817360	0.53	Gm24786	predicted gene, 24786	12444	0.18
chr18_12786708_12786879	0.53	Osbpl1a	oxysterol binding protein-like 1A	19656	0.15
chr13_97253316_97253595	0.52	Enc1	ectodermal-neural cortex 1	12350	0.16
chr11_75294860_75295147	0.52	Gm47300	predicted gene, 47300	23605	0.12
chr10_57727739_57727910	0.52	Pkib	protein kinase inhibitor beta, cAMP dependent, testis specific	157	0.96
chr3_132707761_132707914	0.52	Aimp1	aminoacyl tRNA synthetase complex-interacting multifunctional protein 1	23467	0.14
chr7_132931708_132932726	0.52	1500002F19Rik	RIKEN cDNA 1500002F19 gene	1020	0.34
chr1_151130201_151130735	0.52	Gm8941	predicted gene 8941	6039	0.13
chr14_32861212_32861363	0.52	Vstm4	V-set and transmembrane domain containing 4	4531	0.21
chr11_84440515_84440675	0.52	Aatf	apoptosis antagonizing transcription factor	8938	0.25
chr4_106262816_106262980	0.51	Gm12731	predicted gene 12731	5867	0.16
chr10_84968958_84969109	0.51	Ric8b	RIC8 guanine nucleotide exchange factor B	31640	0.19
chr1_61143547_61143729	0.50	Gm11590	predicted gene 11590	19634	0.19
chr1_164435096_164435776	0.50	Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	8283	0.15
chr7_145111866_145112053	0.50	Gm45181	predicted gene 45181	51037	0.14
chr12_117657844_117658030	0.50	Rapgef5	Rap guanine nucleotide exchange factor (GEF) 5	97	0.98
chr18_46630827_46631001	0.50	Gm3734	predicted gene 3734	107	0.96
chr7_35335164_35335341	0.50	Rhpn2	rhophilin, Rho GTPase binding protein 2	922	0.49
chrX_38473317_38473492	0.50	Gm7598	predicted gene 7598	3057	0.24
chr1_23187785_23188477	0.50	Gm29506	predicted gene 29506	47542	0.11
chr15_36716195_36716361	0.50	Gm49263	predicted gene, 49263	7369	0.15
chr18_84860562_84860781	0.49	Gm16146	predicted gene 16146	1085	0.46
chr2_151973210_151973373	0.49	Fam110a	family with sequence similarity 110, member A	103	0.95
chr11_75212399_75212559	0.49	Rtn4rl1	reticulon 4 receptor-like 1	18696	0.1
chr10_85162328_85162479	0.49	Cry1	cryptochrome 1 (photolyase-like)	11047	0.18
chrX_18883144_18883317	0.49	Gm6923	predicted pseudogene 6923	37574	0.2
chr15_54869020_54869389	0.49	Enpp2	ectonucleotide pyrophosphatase/phosphodiesterase 2	6518	0.25
chr10_34513055_34513206	0.49	Frk	fyn-related kinase	29598	0.2
chr10_42082409_42082576	0.48	Tdg-ps2	thymine DNA glycosylase, pseudogene 2	27186	0.19
chr5_113137369_113137527	0.48	2900026A02Rik	RIKEN cDNA 2900026A02 gene	538	0.63
chr5_39219850_39220015	0.48	Gm40293	predicted gene, 40293	87152	0.08
chr9_65201617_65201776	0.47	Rnu5g	RNA, U5G small nuclear	145	0.93
chr9_4380683_4380845	0.47	Msantd4	Myb/SANT-like DNA-binding domain containing 4 with coiled-coils	2771	0.26
chr9_67247634_67247813	0.47	Mir190a	microRNA 190a	10997	0.21
chr2_158078108_158078431	0.47	2010009K17Rik	RIKEN cDNA 2010009K17 gene	13528	0.15
chr14_25508874_25509046	0.47	Zmiz1	zinc finger, MIZ-type containing 1	6305	0.16
chr1_156055780_156055931	0.47	Tor1aip2	torsin A interacting protein 2	7358	0.17
chr14_54417904_54418073	0.46	Slc7a7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7	208	0.86

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Mef2d_Mef2a

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.2	0.6	GO:1902996	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.2	0.6	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.2	0.5	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.2	0.6	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.1	0.6	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1	1.0	GO:0048194	Golgi vesicle budding(GO:0048194)
0.1	0.4	GO:0021564	vagus nerve development(GO:0021564)
0.1	0.7	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.1	0.3	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1	0.3	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.1	0.4	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.6	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	0.2	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1	0.3	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1	0.4	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.1	0.2	GO:0006481	C-terminal protein methylation(GO:0006481)
0.1	0.2	GO:0048320	axial mesoderm formation(GO:0048320)
0.1	0.4	GO:0000820	regulation of glutamine family amino acid metabolic process(GO:0000820)
0.1	0.3	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	0.1	GO:0043096	purine nucleobase salvage(GO:0043096)
0.1	0.1	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1	0.2	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1	0.2	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
0.1	0.3	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1	0.2	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
0.1	0.4	GO:0060613	fat pad development(GO:0060613)
0.1	0.4	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.1	0.2	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1	0.2	GO:0072262	metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.1	0.1	GO:0046061	dATP catabolic process(GO:0046061)
0.1	0.2	GO:0070384	Harderian gland development(GO:0070384)
0.1	0.3	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373)
0.0	0.1	GO:2000481	positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.1	GO:1905216	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0	0.1	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.0	0.1	GO:0065001	specification of axis polarity(GO:0065001)
0.0	0.3	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.1	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.1	GO:0003162	atrioventricular node development(GO:0003162)
0.0	0.2	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.1	GO:0006393	termination of mitochondrial transcription(GO:0006393)
0.0	0.1	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.0	0.2	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.0	0.1	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.4	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.1	GO:0071332	cellular response to fructose stimulus(GO:0071332)
0.0	0.1	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.0	0.1	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.0	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.1	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.0	0.2	GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0	0.2	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.2	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.0	0.7	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.1	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.2	GO:0071073	positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0	0.1	GO:1904220	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:2000619	negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0	0.6	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.2	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.0	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:2000832	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0	0.2	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.0	0.1	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.1	GO:0009177	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.3	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0	0.1	GO:1903818	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0	0.3	GO:0002934	desmosome organization(GO:0002934)
0.0	0.1	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.1	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.0	0.1	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.1	GO:0021593	rhombomere morphogenesis(GO:0021593)
0.0	0.1	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.0	0.1	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.1	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.1	GO:1902990	mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0	0.2	GO:0071501	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.1	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.0	0.2	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0	0.2	GO:0048318	axial mesoderm development(GO:0048318)
0.0	0.1	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.1	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.1	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.2	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.3	GO:0051601	exocyst localization(GO:0051601)
0.0	0.1	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.0	0.1	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0	0.1	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.2	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.2	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.1	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.0	0.1	GO:1903288	regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0	0.1	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.0	0.1	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.0	0.0	GO:0002432	granuloma formation(GO:0002432)
0.0	0.1	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.1	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.2	GO:0018904	ether metabolic process(GO:0018904)
0.0	0.2	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.1	GO:1903207	neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.0	0.0	GO:0072053	renal inner medulla development(GO:0072053)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.1	GO:0009597	detection of virus(GO:0009597)
0.0	0.1	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.0	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0	0.1	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.0	0.2	GO:0071361	cellular response to ethanol(GO:0071361)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.2	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.1	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.0	GO:1902302	regulation of potassium ion export(GO:1902302)
0.0	0.2	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.2	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.1	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.1	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.0	0.0	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.2	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.0	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.1	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.3	GO:0099514	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:0045588	positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0	0.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.1	GO:0007403	glial cell fate determination(GO:0007403)
0.0	0.1	GO:0001827	inner cell mass cell fate commitment(GO:0001827)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.8	GO:0015909	long-chain fatty acid transport(GO:0015909)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0	0.1	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0	0.1	GO:0071374	cellular response to parathyroid hormone stimulus(GO:0071374)
0.0	0.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.3	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838)
0.0	0.1	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.1	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.0	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.0	GO:0060978	angiogenesis involved in coronary vascular morphogenesis(GO:0060978)
0.0	1.0	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.0	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0090042	tubulin deacetylation(GO:0090042)
0.0	0.1	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.0	0.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	0.1	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0	0.2	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.0	0.2	GO:0032308	positive regulation of prostaglandin secretion(GO:0032308)
0.0	0.3	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.1	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0	0.2	GO:0090049	regulation of cell migration involved in sprouting angiogenesis(GO:0090049)
0.0	0.1	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.1	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.1	GO:0036506	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0	0.0	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.0	0.0	GO:0036515	serotonergic neuron axon guidance(GO:0036515)
0.0	0.0	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.0	0.0	GO:0046337	phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.1	GO:0035865	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.1	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.0	0.0	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0	0.1	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.0	0.0	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
0.0	0.1	GO:2000402	negative regulation of lymphocyte migration(GO:2000402)
0.0	0.1	GO:1901894	regulation of calcium-transporting ATPase activity(GO:1901894)
0.0	0.0	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.1	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0	0.3	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:2000109	macrophage apoptotic process(GO:0071888) regulation of macrophage apoptotic process(GO:2000109)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.2	GO:0010667	negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.1	GO:1904322	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0	0.0	GO:0032439	endosome localization(GO:0032439)
0.0	0.1	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	0.0	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
0.0	0.0	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.0	0.0	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0	0.0	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.0	0.0	GO:0000059	protein import into nucleus, docking(GO:0000059)
0.0	0.1	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
0.0	0.0	GO:0060618	nipple development(GO:0060618)
0.0	0.1	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.0	GO:0046060	dATP metabolic process(GO:0046060)
0.0	0.0	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress(GO:0036003)
0.0	0.2	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.3	GO:0051642	centrosome localization(GO:0051642)
0.0	0.2	GO:0006907	pinocytosis(GO:0006907)
0.0	0.0	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	0.1	GO:0060056	mammary gland involution(GO:0060056)
0.0	0.0	GO:0030035	microspike assembly(GO:0030035)
0.0	0.1	GO:0032596	protein transport into membrane raft(GO:0032596)
0.0	0.1	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.1	GO:0097461	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.0	GO:1902263	apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0	0.1	GO:2000726	negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.0	0.1	GO:0035728	response to hepatocyte growth factor(GO:0035728) cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0	0.1	GO:0009115	xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
0.0	0.1	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.0	GO:0035622	intrahepatic bile duct development(GO:0035622)
0.0	0.1	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.0	0.0	GO:0010796	regulation of multivesicular body size(GO:0010796)
0.0	0.1	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.0	0.0	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.1	GO:0002786	regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.0	0.0	GO:0032484	Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0	0.2	GO:0006298	mismatch repair(GO:0006298)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.1	GO:0030575	nuclear body organization(GO:0030575)
0.0	0.0	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.0	GO:0006382	adenosine to inosine editing(GO:0006382)
0.0	0.1	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.0	GO:0042126	nitrate metabolic process(GO:0042126)
0.0	0.0	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0	0.0	GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.1	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.0	0.1	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	0.7	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.0	GO:0060029	convergent extension involved in organogenesis(GO:0060029)
0.0	0.0	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.0	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.0	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0	0.0	GO:0002461	tolerance induction dependent upon immune response(GO:0002461)
0.0	0.1	GO:0014041	regulation of neuron maturation(GO:0014041)
0.0	0.0	GO:0001757	somite specification(GO:0001757)
0.0	0.0	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
0.0	0.0	GO:0072235	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0	0.2	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.0	GO:0051122	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.0	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.3	GO:0046627	negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0	0.1	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.0	0.0	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.0	GO:0003383	apical constriction(GO:0003383)
0.0	0.0	GO:1904252	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0	0.0	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.0	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.0	0.0	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0	0.0	GO:0015780	nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.0	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0	0.0	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.3	GO:0035458	cellular response to interferon-beta(GO:0035458)
0.0	0.0	GO:0071798	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.1	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0	0.1	GO:0051013	microtubule severing(GO:0051013)
0.0	0.0	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0	0.1	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.2	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.0	GO:1902534	single-organism membrane invagination(GO:1902534)
0.0	0.1	GO:0036010	protein localization to endosome(GO:0036010)
0.0	0.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.0	GO:1903416	response to glycoside(GO:1903416)
0.0	0.0	GO:2000599	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.0	0.0	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.2	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.0	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0	0.0	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.0	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0	0.0	GO:2000674	regulation of type B pancreatic cell apoptotic process(GO:2000674)
0.0	0.0	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0	0.0	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.0	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.1	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.0	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0	0.0	GO:0015888	thiamine transport(GO:0015888)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0032127	dense core granule membrane(GO:0032127)
0.2	1.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.2	0.6	GO:0097418	neurofibrillary tangle(GO:0097418)
0.1	0.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.3	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
0.0	0.6	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.3	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.3	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.2	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0097513	myosin II filament(GO:0097513)
0.0	0.1	GO:1990246	uniplex complex(GO:1990246)
0.0	0.2	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.3	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.2	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0	0.1	GO:0097512	cardiac myofibril(GO:0097512)
0.0	0.1	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.2	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.2	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.4	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.1	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.0	1.0	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.0	0.2	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0002081	outer acrosomal membrane(GO:0002081)
0.0	0.1	GO:0005587	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0	0.0	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.0	GO:0046691	intracellular canaliculus(GO:0046691)
0.0	0.3	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.0	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0060091	kinocilium(GO:0060091)
0.0	0.1	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0097255	R2TP complex(GO:0097255)
0.0	0.2	GO:0071564	npBAF complex(GO:0071564)
0.0	0.0	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.0	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.1	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.0	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.1	GO:0001651	dense fibrillar component(GO:0001651)
0.0	0.1	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	1.0	GO:0016607	nuclear speck(GO:0016607)
0.0	0.2	GO:0045120	pronucleus(GO:0045120)
0.0	0.0	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0	0.2	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.1	GO:0000243	commitment complex(GO:0000243)
0.0	0.9	GO:0000922	spindle pole(GO:0000922)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.1	0.5	GO:0042731	PH domain binding(GO:0042731)
0.1	0.6	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.8	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.1	0.3	GO:0015186	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.1	0.7	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.2	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.1	0.2	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	0.2	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	0.2	GO:0070905	serine binding(GO:0070905)
0.1	1.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.1	0.6	GO:0035497	cAMP response element binding(GO:0035497)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.2	GO:0004103	choline kinase activity(GO:0004103)
0.1	0.2	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0033142	progesterone receptor binding(GO:0033142)
0.0	0.6	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.5	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
0.0	0.1	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.0	0.1	GO:0070538	oleic acid binding(GO:0070538)
0.0	0.2	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.2	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0	0.1	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.0	0.4	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.3	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	1.3	GO:0043531	ADP binding(GO:0043531)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.3	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.3	GO:0030983	mismatched DNA binding(GO:0030983)
0.0	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.8	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.2	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0	0.1	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.9	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.3	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0003933	GTP cyclohydrolase activity(GO:0003933)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.5	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.0	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.2	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.0	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.0	GO:0032557	pyrimidine ribonucleotide binding(GO:0032557)
0.0	0.0	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.1	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.3	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.2	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.0	0.1	GO:0000182	rDNA binding(GO:0000182)
0.0	0.1	GO:0016936	galactoside binding(GO:0016936)
0.0	0.1	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0070061	fructose binding(GO:0070061)
0.0	0.2	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.1	GO:0032554	purine deoxyribonucleotide binding(GO:0032554)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.0	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.1	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.0	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
0.0	0.1	GO:0070698	type I activin receptor binding(GO:0070698)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.1	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0	0.1	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.1	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0	0.1	GO:0016208	AMP binding(GO:0016208)
0.0	0.2	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.0	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.0	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	0.0	GO:0016726	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.8	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.3	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.5	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.0	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	0.1	GO:0018448	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.0	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.0	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.1	GO:0016453	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0	0.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.2	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.1	GO:1990446	U1 snRNP binding(GO:1990446)
0.0	0.6	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	0.0	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.1	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.1	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.1	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.0	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.1	GO:0048185	activin binding(GO:0048185)
0.0	0.0	GO:0070573	metallodipeptidase activity(GO:0070573)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.0	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0	0.0	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.2	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.0	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.0	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0	0.2	GO:0010857	calcium-dependent protein kinase activity(GO:0010857)
0.0	0.1	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.0	0.1	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	0.0	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.0	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.0	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.0	GO:0008308	voltage-gated anion channel activity(GO:0008308)
0.0	0.0	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.1	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	2.5	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	0.0	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.0	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.0	0.1	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	0.0	GO:0047751	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.0	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0	0.1	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	1.5	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.4	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	1.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.6	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.0	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.4	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.8	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.5	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.3	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.4	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.0	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.1	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.3	PID ATM PATHWAY	ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	1.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	0.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	1.1	REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.0	0.9	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.5	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	1.1	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.0	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.1	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	0.5	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.3	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	1.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.4	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.3	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.0	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.0	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.2	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.4	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.0	0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.0	REACTOME SIGNAL AMPLIFICATION	Genes involved in Signal amplification
0.0	0.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease

Results for Mef2d_Mef2a

Z-value: 1.79

Motif logo

Transcription factors associated with Mef2d_Mef2a

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Mef2d_Mef2a motif across conditions

Conditions sorted by the z-value of the Mef2d_Mef2a motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Mef2d_Mef2a

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: