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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Meox2

Z-value: 1.90

Motif logo

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Transcription factors associated with Meox2

Gene Symbol Gene ID Gene Info
ENSMUSG00000036144.5 Meox2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

GenePromoterDistanceAssociation probabilityPearson corr. coef.P-valuePlot
Meox2chr12_37167805_37167956593400.112105-0.414.2e-01Click!

Activity of the Meox2 motif across conditions

Conditions sorted by the z-value of the Meox2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_21250942_21251436 1.04 Gsta3
glutathione S-transferase, alpha 3
2332
0.18
chr3_97635501_97635936 0.99 Fmo5
flavin containing monooxygenase 5
6835
0.14
chr3_81955296_81955447 0.99 Ctso
cathepsin O
4434
0.18
chr18_86383968_86384119 0.89 Neto1
neuropilin (NRP) and tolloid (TLL)-like 1
10909
0.24
chr9_122148667_122148818 0.84 Gm47121
predicted gene, 47121
6293
0.13
chr1_140421414_140421565 0.84 Kcnt2
potassium channel, subfamily T, member 2
21447
0.27
chr1_80244319_80244685 0.84 Gm37932
predicted gene, 37932
11695
0.13
chr14_30542112_30542288 0.76 Tkt
transketolase
6159
0.16
chr10_69208679_69208830 0.76 Rhobtb1
Rho-related BTB domain containing 1
202
0.94
chr1_97770980_97771325 0.73 Ppip5k2
diphosphoinositol pentakisphosphate kinase 2
741
0.49
chr8_93185394_93185584 0.73 Gm45909
predicted gene 45909
5869
0.14
chr8_109981175_109981347 0.73 Gm45795
predicted gene 45795
6909
0.13
chr5_87589802_87589979 0.72 Sult1e1
sulfotransferase family 1E, member 1
1704
0.22
chr1_23237656_23237879 0.70 Gm29506
predicted gene 29506
2094
0.23
chr4_88893074_88893256 0.69 Ifne
interferon epsilon
12964
0.08
chr6_108836766_108836917 0.64 Edem1
ER degradation enhancer, mannosidase alpha-like 1
431
0.86
chr13_93719775_93719928 0.64 AW495222
expressed sequence AW495222
676
0.6
chr11_28689224_28689493 0.64 2810471M01Rik
RIKEN cDNA 2810471M01 gene
7794
0.19
chr1_156978437_156978634 0.63 4930439D14Rik
RIKEN cDNA 4930439D14 gene
38697
0.12
chr13_104044189_104044340 0.63 Nln
neurolysin (metallopeptidase M3 family)
6622
0.22
chr1_67162712_67162908 0.63 Cps1
carbamoyl-phosphate synthetase 1
39784
0.16
chr1_67165771_67165961 0.62 Cps1
carbamoyl-phosphate synthetase 1
42840
0.16
chr16_42998647_42998825 0.61 Ndufs5-ps
NADH:ubiquinone oxidoreductase core subunit S5, pseudogene
43105
0.16
chr1_160781397_160781614 0.61 Rabgap1l
RAB GTPase activating protein 1-like
11433
0.12
chr6_58611375_58611579 0.60 Abcg2
ATP binding cassette subfamily G member 2 (Junior blood group)
14806
0.19
chr3_112120839_112120990 0.60 Gm25519
predicted gene, 25519
78127
0.1
chr7_114361745_114361949 0.59 4933406I18Rik
RIKEN cDNA 4933406I18 gene
53174
0.12
chr13_4077186_4077340 0.59 Akr1c14
aldo-keto reductase family 1, member C14
991
0.44
chr2_93821900_93822368 0.59 Ext2
exostosin glycosyltransferase 2
411
0.82
chr4_15029409_15029632 0.59 Gm11844
predicted gene 11844
6938
0.27
chr11_52374066_52374363 0.56 Vdac1
voltage-dependent anion channel 1
49
0.97
chr4_108060521_108060686 0.56 Scp2
sterol carrier protein 2, liver
10760
0.13
chr17_80022007_80022158 0.56 Gm22215
predicted gene, 22215
11432
0.14
chr11_28694681_28694832 0.55 2810471M01Rik
RIKEN cDNA 2810471M01 gene
13192
0.17
chr13_93623443_93623622 0.54 Gm15622
predicted gene 15622
1850
0.3
chr2_160805166_160805505 0.54 Gm11447
predicted gene 11447
40278
0.11
chr16_7049906_7050057 0.54 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
19865
0.3
chr14_45659577_45659728 0.54 Ddhd1
DDHD domain containing 1
1509
0.23
chr12_80336463_80336614 0.54 Dcaf5
DDB1 and CUL4 associated factor 5
40154
0.1
chr6_120318643_120318978 0.54 B4galnt3
beta-1,4-N-acetyl-galactosaminyl transferase 3
24251
0.15
chr3_107690573_107690757 0.54 Ahcyl1
S-adenosylhomocysteine hydrolase-like 1
5298
0.18
chr18_75675824_75676322 0.53 Ctif
CBP80/20-dependent translation initiation factor
21481
0.23
chr17_43672210_43672361 0.53 Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
4760
0.18
chr16_26694594_26694745 0.53 Il1rap
interleukin 1 receptor accessory protein
27765
0.23
chr8_109995374_109995556 0.53 Tat
tyrosine aminotransferase
4959
0.13
chr3_144110488_144110677 0.52 Gm34078
predicted gene, 34078
25172
0.2
chr6_4820679_4820851 0.52 Gm20714
predicted gene 20714
4436
0.18
chr19_21158185_21158336 0.52 AC106834.1
novel transcript
12581
0.21
chr11_88618341_88618520 0.51 Msi2
musashi RNA-binding protein 2
28283
0.2
chr12_73861884_73862127 0.51 Gm15283
predicted gene 15283
7607
0.18
chr8_56345237_56345388 0.51 Gm45540
predicted gene 45540
34008
0.18
chr18_38176274_38176683 0.51 Pcdh1
protocadherin 1
26685
0.12
chr3_5425056_5425268 0.51 4930555M17Rik
RIKEN cDNA 4930555M17 gene
90171
0.09
chr17_45879729_45879910 0.50 4930542M03Rik
RIKEN cDNA 4930542M03 gene
1633
0.33
chr13_89583759_89583911 0.50 Hapln1
hyaluronan and proteoglycan link protein 1
676
0.73
chr8_86599602_86599753 0.50 Gm44348
predicted gene, 44348
12715
0.16
chr2_84379041_84379217 0.50 Calcrl
calcitonin receptor-like
3771
0.25
chr16_37874310_37874496 0.50 Lrrc58
leucine rich repeat containing 58
6014
0.14
chr3_51204305_51204466 0.49 Noct
nocturnin
20062
0.14
chr9_47348407_47348558 0.49 Gm31816
predicted gene, 31816
14268
0.26
chr13_52771924_52772129 0.49 BB123696
expressed sequence BB123696
14821
0.27
chr3_111102424_111102592 0.48 Gm43407
predicted gene 43407
5992
0.34
chr7_118146005_118146156 0.48 Smg1
SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
4281
0.18
chr8_104787830_104787982 0.47 Gm45782
predicted gene 45782
2078
0.17
chr2_64094972_64095229 0.47 Fign
fidgetin
2888
0.42
chr4_139111685_139111987 0.47 Micos10
mitochondrial contact site and cristae organizing system subunit 10
593
0.66
chr3_12608407_12608567 0.47 Gm2429
predicted gene 2429
22773
0.28
chr11_31875210_31875374 0.46 Cpeb4
cytoplasmic polyadenylation element binding protein 4
2017
0.35
chr4_53395599_53395871 0.46 Gm12496
predicted gene 12496
8295
0.23
chr2_10369756_10369912 0.46 Sfmbt2
Scm-like with four mbt domains 2
676
0.33
chr10_87040962_87041138 0.46 1700113H08Rik
RIKEN cDNA 1700113H08 gene
16995
0.16
chr4_82355326_82355477 0.46 n-R5s188
nuclear encoded rRNA 5S 188
84009
0.1
chr18_61841168_61841343 0.46 Afap1l1
actin filament associated protein 1-like 1
54553
0.1
chr1_180179778_180180226 0.46 Coq8a
coenzyme Q8A
1080
0.44
chr19_44401346_44401497 0.45 Scd1
stearoyl-Coenzyme A desaturase 1
5269
0.16
chr17_32493567_32493723 0.45 Cyp4f39
cytochrome P450, family 4, subfamily f, polypeptide 39
1487
0.3
chr8_100855820_100856252 0.45 Gm39232
predicted gene, 39232
129681
0.06
chr13_108346244_108346395 0.45 Depdc1b
DEP domain containing 1B
11107
0.19
chr13_93626581_93626763 0.45 Gm15622
predicted gene 15622
1290
0.4
chr1_97603062_97603228 0.45 AC099860.1
proline rich protein BstNI subfamily 4 (PRB4), pseudogene
57686
0.11
chr10_89492629_89492900 0.44 Nr1h4
nuclear receptor subfamily 1, group H, member 4
13885
0.21
chr7_139684440_139684595 0.44 Cfap46
cilia and flagella associated protein 46
700
0.66
chr1_65167472_65167777 0.44 Idh1
isocitrate dehydrogenase 1 (NADP+), soluble
7940
0.14
chr9_107853667_107853838 0.44 Rbm6
RNA binding motif protein 6
2319
0.17
chr2_19659363_19659514 0.44 Otud1
OTU domain containing 1
1686
0.26
chr3_35169015_35169202 0.44 1700017M07Rik
RIKEN cDNA 1700017M07 gene
107023
0.07
chr3_131638032_131638214 0.44 Gm42881
predicted gene 42881
24343
0.22
chr3_51437862_51438013 0.44 Naa15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
2980
0.14
chr14_21161568_21161719 0.44 Adk
adenosine kinase
85491
0.09
chr11_17745312_17745477 0.44 Gm12016
predicted gene 12016
106211
0.07
chr18_39483316_39483539 0.44 Nr3c1
nuclear receptor subfamily 3, group C, member 1
3805
0.31
chr10_13985883_13986077 0.44 Hivep2
human immunodeficiency virus type I enhancer binding protein 2
18956
0.19
chr15_62121397_62121548 0.44 Pvt1
Pvt1 oncogene
22443
0.25
chr10_10843070_10843258 0.43 4930567K20Rik
RIKEN cDNA 4930567K20 gene
92084
0.07
chr10_61139154_61139351 0.43 Sgpl1
sphingosine phosphate lyase 1
7646
0.15
chr15_50404034_50404185 0.43 Gm49198
predicted gene, 49198
117211
0.07
chr7_75852856_75853007 0.43 Klhl25
kelch-like 25
4490
0.26
chr18_12799044_12799195 0.43 Osbpl1a
oxysterol binding protein-like 1A
20479
0.15
chr6_29772335_29772499 0.43 Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
3889
0.2
chr14_8003834_8004016 0.43 Abhd6
abhydrolase domain containing 6
959
0.54
chr3_95435996_95436155 0.43 Arnt
aryl hydrocarbon receptor nuclear translocator
1556
0.21
chr1_69108268_69108432 0.42 Erbb4
erb-b2 receptor tyrosine kinase 4
291
0.88
chr4_101198122_101198415 0.42 Gm24468
predicted gene, 24468
11504
0.14
chr5_54000014_54000256 0.42 Stim2
stromal interaction molecule 2
1570
0.48
chr3_133740753_133740929 0.42 Gm6135
prediticted gene 6135
50663
0.13
chr19_12685171_12685322 0.42 Gm49772
predicted gene, 49772
3475
0.12
chr6_51695515_51695666 0.42 Gm38811
predicted gene, 38811
15491
0.23
chr8_24524982_24525133 0.42 Ido2
indoleamine 2,3-dioxygenase 2
15739
0.16
chr8_72420483_72420634 0.42 Eps15l1
epidermal growth factor receptor pathway substrate 15-like 1
880
0.31
chr16_85704612_85704964 0.42 Gm6278
predicted gene 6278
60536
0.13
chr8_84773010_84773167 0.42 Nfix
nuclear factor I/X
308
0.82
chr19_31898515_31898680 0.42 Gm19241
predicted gene, 19241
15047
0.2
chr19_34523065_34523384 0.41 Lipa
lysosomal acid lipase A
4187
0.15
chr9_46036951_46037323 0.41 Sik3
SIK family kinase 3
24137
0.13
chr9_9228799_9229183 0.41 Gm16833
predicted gene, 16833
7297
0.23
chr13_51093099_51093344 0.41 Spin1
spindlin 1
7659
0.25
chr1_163817675_163817827 0.41 Kifap3
kinesin-associated protein 3
38168
0.16
chr8_110644559_110644860 0.41 Vac14
Vac14 homolog (S. cerevisiae)
871
0.63
chr12_99351809_99352026 0.41 Foxn3
forkhead box N3
5102
0.14
chr1_155896484_155896645 0.41 Cep350
centrosomal protein 350
1967
0.24
chr19_44394517_44394772 0.41 Scd1
stearoyl-Coenzyme A desaturase 1
12046
0.14
chr17_49304784_49304935 0.41 Gm17830
predicted gene, 17830
7382
0.19
chr2_84359341_84359492 0.41 Calcrl
calcitonin receptor-like
15942
0.19
chr17_15372349_15372526 0.40 Dll1
delta like canonical Notch ligand 1
606
0.69
chr10_61135528_61135708 0.40 Gm44308
predicted gene, 44308
10383
0.14
chr7_134192391_134192592 0.40 Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
19547
0.21
chr1_48446424_48446607 0.40 Gm23240
predicted gene, 23240
15778
0.27
chr1_191945292_191945694 0.40 Rd3
retinal degeneration 3
31877
0.1
chr2_31513022_31513372 0.40 Ass1
argininosuccinate synthetase 1
5293
0.19
chrX_142477976_142478290 0.40 Gm25915
predicted gene, 25915
7314
0.19
chrX_164281566_164281717 0.40 Gm22023
predicted gene, 22023
1455
0.35
chr16_76432143_76432294 0.40 Gm9843
predicted gene 9843
28566
0.17
chr7_102310929_102311109 0.40 Stim1
stromal interaction molecule 1
42692
0.09
chr15_59067650_59068255 0.40 Mtss1
MTSS I-BAR domain containing 1
12488
0.22
chr1_67214555_67214706 0.40 Gm15668
predicted gene 15668
34570
0.17
chr11_116211852_116212160 0.39 Ten1
TEN1 telomerase capping complex subunit
1072
0.32
chr1_67227292_67227476 0.39 Gm15668
predicted gene 15668
21816
0.2
chr19_42540662_42540829 0.39 R3hcc1l
R3H domain and coiled-coil containing 1 like
21923
0.17
chr12_100795519_100795676 0.39 Dglucy
D-glutamate cyclase
9455
0.15
chr11_14186035_14186200 0.39 4930554G24Rik
RIKEN cDNA 4930554G24 gene
7076
0.27
chr19_30093178_30093359 0.39 Uhrf2
ubiquitin-like, containing PHD and RING finger domains 2
1307
0.48
chr17_84997546_84997697 0.39 Ppm1b
protein phosphatase 1B, magnesium dependent, beta isoform
3941
0.22
chr17_46059620_46059782 0.39 Gm36200
predicted gene, 36200
24565
0.11
chr3_70400102_70400273 0.39 Gm6631
predicted gene 6631
13132
0.29
chr17_83310756_83310907 0.39 Rpl21-ps7
ribosomal protein L21, pseudogene 7
22285
0.18
chr5_45474015_45474198 0.39 Lap3
leucine aminopeptidase 3
19268
0.11
chr3_57743459_57743610 0.38 Rnf13
ring finger protein 13
7414
0.14
chr6_116120008_116120203 0.38 Tmcc1
transmembrane and coiled coil domains 1
9711
0.15
chr8_33384837_33385055 0.38 Wrn
Werner syndrome RecQ like helicase
526
0.72
chr9_106245058_106245282 0.38 Alas1
aminolevulinic acid synthase 1
1536
0.23
chr4_76942079_76942249 0.38 Gm11246
predicted gene 11246
14853
0.22
chr6_38815502_38815672 0.38 Hipk2
homeodomain interacting protein kinase 2
2759
0.33
chr10_24912717_24913171 0.38 Mir6905
microRNA 6905
2280
0.2
chr5_89342174_89342864 0.38 Gc
vitamin D binding protein
93109
0.09
chr16_42998396_42998547 0.38 Ndufs5-ps
NADH:ubiquinone oxidoreductase core subunit S5, pseudogene
42840
0.16
chr7_128640219_128640376 0.38 Inpp5f
inositol polyphosphate-5-phosphatase F
18711
0.11
chr3_5346748_5346907 0.38 Zfhx4
zinc finger homeodomain 4
105155
0.07
chr13_81333716_81333867 0.38 Adgrv1
adhesion G protein-coupled receptor V1
9045
0.27
chr9_48739787_48740228 0.37 Zbtb16
zinc finger and BTB domain containing 16
95938
0.07
chr1_67227779_67227978 0.37 Gm15668
predicted gene 15668
21322
0.2
chr4_97900129_97900314 0.37 Nfia
nuclear factor I/A
10812
0.29
chr2_116075832_116075983 0.37 2810405F15Rik
RIKEN cDNA 2810405F15 gene
189
0.94
chr14_17864277_17864546 0.37 Gm48320
predicted gene, 48320
93289
0.08
chr7_98384449_98384600 0.37 Tsku
tsukushi, small leucine rich proteoglycan
23196
0.13
chr8_14548995_14549164 0.37 Dlgap2
DLG associated protein 2
167083
0.03
chr12_40016661_40016850 0.37 Arl4a
ADP-ribosylation factor-like 4A
2271
0.3
chr6_50215446_50215627 0.37 Mpp6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
21120
0.2
chr9_23224794_23225147 0.37 Bmper
BMP-binding endothelial regulator
1684
0.55
chr1_21297964_21298132 0.37 Gm4956
predicted gene 4956
79
0.95
chr18_65034546_65034697 0.37 Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
8819
0.23
chr13_119456737_119456888 0.37 4833420G17Rik
RIKEN cDNA 4833420G17 gene
5956
0.14
chr1_72009620_72009955 0.37 4933417E11Rik
RIKEN cDNA 4933417E11 gene
4592
0.18
chr15_66074633_66074784 0.36 Gm27153
predicted gene 27153
156
0.97
chr8_18713888_18714465 0.36 Angpt2
angiopoietin 2
14629
0.17
chr15_3430435_3430588 0.36 Ghr
growth hormone receptor
41133
0.19
chr10_115388269_115388460 0.36 Zfc3h1
zinc finger, C3H1-type containing
3405
0.17
chr1_67170087_67170238 0.36 Cps1
carbamoyl-phosphate synthetase 1
47136
0.14
chr4_97025279_97025435 0.36 Gm27521
predicted gene, 27521
108337
0.07
chr7_66724393_66724565 0.36 Gm45098
predicted gene 45098
1360
0.35
chr9_66590494_66590818 0.36 Usp3
ubiquitin specific peptidase 3
2302
0.3
chr3_52544102_52544286 0.36 Gm30173
predicted gene, 30173
27230
0.2
chr2_144600133_144600679 0.36 Dtd1
D-tyrosyl-tRNA deacylase 1
509
0.71
chr19_40141682_40141833 0.36 Cyp2c70
cytochrome P450, family 2, subfamily c, polypeptide 70
45529
0.11
chr2_18059830_18059981 0.36 Mir7655
microRNA 7655
2059
0.18
chr19_58421573_58421724 0.35 Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
32818
0.19
chr5_77357793_77357964 0.35 Polr2b
polymerase (RNA) II (DNA directed) polypeptide B
17510
0.13
chr12_118313299_118313450 0.35 Sp4
trans-acting transcription factor 4
11934
0.27
chr7_98430701_98430878 0.35 Gm44980
predicted gene 44980
6730
0.13
chr7_104995535_104995703 0.35 Olfr672
olfactory receptor 672
1283
0.2
chr12_7816660_7817001 0.35 Gm32828
predicted gene, 32828
42861
0.14
chr2_155587050_155587219 0.35 Gss
glutathione synthetase
442
0.63
chr2_26593869_26594069 0.35 Egfl7
EGF-like domain 7
1822
0.16
chr10_59549383_59549552 0.35 Gm10322
predicted gene 10322
66596
0.1
chr2_118839517_118839869 0.35 Gm14091
predicted gene 14091
5571
0.14
chr5_5514010_5514339 0.35 Cldn12
claudin 12
275
0.9
chr16_13257585_13257940 0.35 Mrtfb
myocardin related transcription factor B
1256
0.58
chr11_90184166_90184514 0.35 n-R5s72
nuclear encoded rRNA 5S 72
787
0.57
chr19_42118053_42118204 0.35 Pi4k2a
phosphatidylinositol 4-kinase type 2 alpha
3450
0.14
chr13_29774433_29774613 0.35 Cdkal1
CDK5 regulatory subunit associated protein 1-like 1
80908
0.11
chr4_141158698_141158852 0.35 Fbxo42
F-box protein 42
10853
0.12

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Meox2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.2 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 1.0 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.4 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.1 0.3 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.3 GO:0010963 regulation of L-arginine import(GO:0010963)
0.1 0.5 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.3 GO:0001757 somite specification(GO:0001757)
0.1 0.3 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.1 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.2 GO:0015747 urate transport(GO:0015747)
0.1 0.2 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.3 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:0006549 isoleucine metabolic process(GO:0006549)
0.1 0.3 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.1 0.3 GO:0019478 D-amino acid catabolic process(GO:0019478)
0.1 0.1 GO:0048696 regulation of collateral sprouting in absence of injury(GO:0048696)
0.1 0.2 GO:0071727 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.2 GO:0038171 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.1 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.3 GO:1904528 regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.1 0.2 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1 0.2 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 0.1 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.2 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.2 GO:0090296 regulation of mitochondrial DNA replication(GO:0090296)
0.1 0.2 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.5 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.4 GO:0071265 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.1 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.1 0.2 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.1 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.4 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.0 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.0 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.2 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:1902488 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0 0.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.5 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.2 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 0.1 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.1 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0 0.3 GO:0009074 aromatic amino acid family catabolic process(GO:0009074)
0.0 0.0 GO:0032741 positive regulation of interleukin-18 production(GO:0032741)
0.0 0.5 GO:2000010 positive regulation of protein localization to cell surface(GO:2000010)
0.0 0.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.0 0.1 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.2 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 0.1 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 0.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.2 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.0 0.2 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.1 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.0 0.1 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.0 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.1 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.1 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.1 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.0 0.2 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0060696 regulation of phospholipid catabolic process(GO:0060696)
0.0 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.0 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0 0.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.2 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.1 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.1 GO:1903969 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.0 0.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.1 GO:1902047 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.0 0.0 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.4 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.1 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.1 GO:0072602 interleukin-4 secretion(GO:0072602)
0.0 0.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.0 GO:0060375 regulation of mast cell differentiation(GO:0060375)
0.0 0.2 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.0 0.0 GO:0021683 cerebellar granular layer morphogenesis(GO:0021683)
0.0 0.1 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.0 0.0 GO:0009698 phenylpropanoid metabolic process(GO:0009698) phenylpropanoid catabolic process(GO:0046271)
0.0 0.1 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.2 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.3 GO:0035510 DNA dealkylation(GO:0035510)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.1 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.0 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0 0.1 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.2 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.0 GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.2 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.1 GO:0032621 interleukin-18 production(GO:0032621)
0.0 0.0 GO:0075136 response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.0 0.0 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 0.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.0 GO:0048296 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.2 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.0 0.0 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.0 GO:0061317 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:0030638 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.0 GO:0033387 putrescine biosynthetic process(GO:0009446) putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.0 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0 0.2 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 0.0 GO:0099515 actin filament-based transport(GO:0099515)
0.0 0.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.0 GO:1903011 negative regulation of bone development(GO:1903011)
0.0 0.0 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.1 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.0 GO:1903061 positive regulation of protein lipidation(GO:1903061)
0.0 0.0 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.0 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.0 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.0 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.0 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.0 0.0 GO:0021898 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.0 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.0 GO:1990036 calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0 0.1 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.0 GO:0035973 aggrephagy(GO:0035973)
0.0 0.0 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.0 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.0 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.1 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 0.3 GO:0060074 synapse maturation(GO:0060074)
0.0 0.0 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.1 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0 0.1 GO:0018214 protein carboxylation(GO:0018214)
0.0 0.0 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.0 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.0 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 0.2 GO:0043574 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.0 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.0 GO:0015755 fructose transport(GO:0015755)
0.0 0.0 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0 0.3 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.1 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
0.0 0.0 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.0 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.0 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.0 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.1 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.0 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.0 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.0 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
0.0 0.0 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.0 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.0 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.0 GO:0036394 amylase secretion(GO:0036394)
0.0 0.1 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.0 GO:0007567 parturition(GO:0007567)
0.0 0.0 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.0 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.0 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.0 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.0 GO:0070827 chromatin maintenance(GO:0070827)
0.0 0.0 GO:0006868 glutamine transport(GO:0006868)
0.0 0.0 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.0 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.0 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:0046083 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.0 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.0 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.0 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.0 GO:0015888 thiamine transport(GO:0015888)
0.0 0.0 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.0 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.1 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.1 GO:0042359 vitamin D metabolic process(GO:0042359)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.1 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.2 GO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.1 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.2 GO:0032437 cuticular plate(GO:0032437)
0.1 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.7 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.0 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.8 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.0 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.0 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.0 GO:0032010 phagolysosome(GO:0032010)
0.0 0.0 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.0 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.0 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.0 GO:0098536 deuterosome(GO:0098536)
0.0 0.0 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.0 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.0 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.0 GO:0009279 cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.1 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.0 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.2 0.5 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.3 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1 0.6 GO:0015288 porin activity(GO:0015288)
0.1 0.4 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.3 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.2 GO:0038181 bile acid receptor activity(GO:0038181)
0.1 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.4 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.3 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.2 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.1 0.2 GO:0032551 UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.2 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.2 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.3 GO:0005167 neurotrophin TRK receptor binding(GO:0005167)
0.0 0.2 GO:0002046 opsin binding(GO:0002046)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.2 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.4 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.5 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.1 GO:0031782 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0035671 enone reductase activity(GO:0035671)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.5 GO:0004118 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.0 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.0 0.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.0 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.0 GO:2001069 glycogen binding(GO:2001069)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.0 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.0 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.0 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.0 0.0 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.0 GO:0008147 structural constituent of bone(GO:0008147)
0.0 0.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.0 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.0 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0043743 cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.0 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.0 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.0 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.0 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.0 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.0 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.0 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.2 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.0 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
0.0 0.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.0 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 1.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.0 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.0 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.0 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage