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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Mga

Z-value: 1.21

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Transcription factors associated with Mga

Gene Symbol	Gene ID	Gene Info
Mga Ensembl NCBI MGI UniProt	ENSMUSG00000033943.9	Mga

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Mga	chr2_119897434_119897605	214	0.922854	-0.88	2.0e-02	Click!
Mga	chr2_119898035_119898287	856	0.554990	0.88	2.2e-02	Click!
Mga	chr2_119897133_119897292	16	0.972614	-0.83	4.2e-02	Click!
Mga	chr2_119902218_119902387	4997	0.175261	-0.80	5.6e-02	Click!
Mga	chr2_119887854_119888033	9285	0.150912	0.75	8.6e-02	Click!

Activity of the Mga motif across conditions

Conditions sorted by the z-value of the Mga motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_125526040_125526191	1.71	Tmem132b	transmembrane protein 132B	5659	0.17
chr6_145866005_145866307	1.60	Bhlhe41	basic helix-loop-helix family, member e41	598	0.7
chr11_7816093_7816451	1.11	Gm27393	predicted gene, 27393	70233	0.13
chr18_38856344_38856590	0.98	Fgf1	fibroblast growth factor 1	2281	0.33
chr14_56617767_56617918	0.95	Gm16573	predicted gene 16573	2655	0.22
chr1_21248997_21249314	0.90	Gsta3	glutathione S-transferase, alpha 3	4366	0.13
chr9_119299844_119299995	0.84	Gm22729	predicted gene, 22729	6838	0.14
chr3_18146058_18146209	0.81	Gm23686	predicted gene, 23686	31492	0.18
chr8_93193292_93193577	0.79	Gm45909	predicted gene 45909	2076	0.23
chr9_21837693_21838006	0.79	Angptl8	angiopoietin-like 8	2339	0.17
chr3_95864904_95865315	0.74	Mrps21	mitochondrial ribosomal protein S21	1802	0.16
chr2_31501565_31501761	0.74	Ass1	argininosuccinate synthetase 1	937	0.56
chr4_76942367_76942518	0.72	Gm11246	predicted gene 11246	15131	0.21
chr10_87865511_87865999	0.70	Igf1os	insulin-like growth factor 1, opposite strand	2374	0.3
chr9_106234809_106235123	0.67	Alas1	aminolevulinic acid synthase 1	2118	0.17
chr2_70838613_70839186	0.67	Tlk1	tousled-like kinase 1	13171	0.18
chr5_125524109_125525122	0.67	Tmem132b	transmembrane protein 132B	7159	0.16
chr3_97653036_97653209	0.65	Prkab2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	5071	0.15
chr2_177470070_177470297	0.65	Zfp970	zinc finger protein 970	5337	0.17
chr15_97032998_97033149	0.65	Slc38a4	solute carrier family 38, member 4	1862	0.46
chr1_67104802_67105196	0.65	Cps1	carbamoyl-phosphate synthetase 1	18027	0.21
chr2_77503355_77503533	0.64	Zfp385b	zinc finger protein 385B	16091	0.23
chr18_75504426_75504613	0.63	Gm10532	predicted gene 10532	10126	0.27
chr11_16821774_16821942	0.63	Egfros	epidermal growth factor receptor, opposite strand	8844	0.22
chr7_70346773_70346973	0.62	Gm44948	predicted gene 44948	823	0.39
chr2_177901070_177901508	0.61	Gm14327	predicted gene 14327	2996	0.19
chr3_97632897_97633210	0.60	Fmo5	flavin containing monooxygenase 5	4170	0.16
chr6_35256147_35256298	0.59	1810058I24Rik	RIKEN cDNA 1810058I24 gene	3490	0.19
chrX_142478453_142478626	0.59	Gm25915	predicted gene, 25915	6908	0.19
chr2_148034677_148034980	0.59	9030622O22Rik	RIKEN cDNA 9030622O22 gene	3442	0.21
chr2_85071327_85071510	0.58	Tnks1bp1	tankyrase 1 binding protein 1	10454	0.12
chr9_48724021_48724519	0.56	Zbtb16	zinc finger and BTB domain containing 16	111675	0.06
chr1_88055038_88055189	0.55	Ugt1a10	UDP glycosyltransferase 1 family, polypeptide A10	275	0.78
chr9_106231818_106232229	0.54	Alas1	aminolevulinic acid synthase 1	5061	0.11
chr2_158413370_158413558	0.54	Ralgapb	Ral GTPase activating protein, beta subunit (non-catalytic)	3362	0.12
chr11_16797325_16797505	0.53	Egfros	epidermal growth factor receptor, opposite strand	33287	0.16
chr11_60205379_60205543	0.53	Srebf1	sterol regulatory element binding transcription factor 1	651	0.56
chr1_92944221_92944381	0.53	Capn10	calpain 10	1597	0.22
chr1_153742082_153742457	0.52	Rgs16	regulator of G-protein signaling 16	1920	0.18
chr7_133011265_133011604	0.51	Ctbp2	C-terminal binding protein 2	3814	0.2
chr6_37542487_37542638	0.50	Gm7463	predicted gene 7463	1148	0.52
chr5_122292884_122293053	0.50	Pptc7	PTC7 protein phosphatase homolog	2804	0.16
chr1_91440412_91440614	0.49	Per2	period circadian clock 2	9352	0.11
chr4_46832518_46832720	0.49	Gabbr2	gamma-aminobutyric acid (GABA) B receptor, 2	27283	0.22
chr6_91580636_91580787	0.49	Gm45215	predicted gene 45215	14047	0.13
chr7_114463119_114463303	0.49	Pde3b	phosphodiesterase 3B, cGMP-inhibited	42967	0.15
chr19_18148360_18148511	0.48	Gm18610	predicted gene, 18610	57360	0.15
chr12_17450888_17451065	0.48	Gm36752	predicted gene, 36752	14358	0.19
chr9_55125183_55125348	0.47	Ube2q2	ubiquitin-conjugating enzyme E2Q family member 2	23589	0.13
chr8_84841387_84841538	0.47	Rad23a	RAD23 homolog A, nucleotide excision repair protein	797	0.35
chr10_68129785_68130007	0.47	Arid5b	AT rich interactive domain 5B (MRF1-like)	6730	0.27
chr11_98295864_98296043	0.46	Gm20644	predicted gene 20644	10571	0.09
chr17_84734402_84734930	0.46	Lrpprc	leucine-rich PPR-motif containing	3482	0.21
chr10_61138290_61138447	0.46	Sgpl1	sphingosine phosphate lyase 1	8530	0.15
chr4_6274068_6274223	0.46	Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	1486	0.41
chr10_87891898_87892303	0.45	Igf1os	insulin-like growth factor 1, opposite strand	28719	0.16
chr4_109105267_109105418	0.45	Osbpl9	oxysterol binding protein-like 9	2689	0.29
chr3_152189220_152189460	0.45	Dnajb4	DnaJ heat shock protein family (Hsp40) member B4	4505	0.14
chr18_56413923_56414074	0.45	Gramd3	GRAM domain containing 3	5172	0.22
chr8_40271252_40271403	0.44	Fgf20	fibroblast growth factor 20	15626	0.2
chr11_28689224_28689493	0.44	2810471M01Rik	RIKEN cDNA 2810471M01 gene	7794	0.19
chr11_3387371_3387539	0.44	Limk2	LIM motif-containing protein kinase 2	16079	0.11
chr14_21422563_21422878	0.43	Gm25864	predicted gene, 25864	27754	0.17
chr7_141373770_141373967	0.43	B230206H07Rik	RIKEN cDNA B230206H07 gene	8758	0.07
chr9_90166671_90167004	0.43	Adamts7	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7	3611	0.19
chr3_129444766_129445057	0.42	Gm5712	predicted gene 5712	11238	0.17
chr19_10060762_10061072	0.42	Fads3	fatty acid desaturase 3	4665	0.15
chr7_90141326_90141489	0.41	Gm45222	predicted gene 45222	4541	0.13
chr9_30906121_30906748	0.41	Adamts15	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15	3223	0.28
chr12_12271220_12271371	0.41	Fam49a	family with sequence similarity 49, member A	9106	0.29
chr1_51815647_51815823	0.41	Myo1b	myosin IB	4811	0.21
chr3_116520495_116520697	0.41	Dbt	dihydrolipoamide branched chain transacylase E2	268	0.83
chr1_9742772_9742949	0.40	1700034P13Rik	RIKEN cDNA 1700034P13 gene	4788	0.16
chr10_96107868_96108070	0.40	Gm49817	predicted gene, 49817	11964	0.16
chr19_40223143_40223322	0.40	Pdlim1	PDZ and LIM domain 1 (elfin)	124	0.95
chr8_93173439_93173590	0.40	Ces1d	carboxylesterase 1D	1775	0.27
chr10_111329724_111329924	0.40	Gm40761	predicted gene, 40761	7300	0.21
chr8_67923947_67924108	0.39	Psd3	pleckstrin and Sec7 domain containing 3	13095	0.23
chr5_124353121_124353272	0.39	Cdk2ap1	CDK2 (cyclin-dependent kinase 2)-associated protein 1	963	0.41
chr16_45924599_45924776	0.38	Gm15640	predicted gene 15640	11636	0.17
chr13_69640079_69640317	0.38	Nsun2	NOL1/NOP2/Sun domain family member 2	9458	0.1
chr6_116056575_116057222	0.38	Tmcc1	transmembrane and coiled coil domains 1	57	0.97
chr1_124069161_124069328	0.38	Dpp10	dipeptidylpeptidase 10	23685	0.27
chr17_64740276_64740464	0.38	Gm17133	predicted gene 17133	13726	0.19
chr11_98563759_98564290	0.37	Zpbp2	zona pellucida binding protein 2	8581	0.11
chrY_90798307_90798477	0.37	Gm47283	predicted gene, 47283	7941	0.18
chr17_5261920_5262119	0.37	Gm29050	predicted gene 29050	126744	0.05
chr5_124234244_124234932	0.37	Gm42425	predicted gene 42425	3136	0.14
chr5_102010547_102010959	0.37	Wdfy3	WD repeat and FYVE domain containing 3	29195	0.16
chr6_52009095_52009246	0.37	Skap2	src family associated phosphoprotein 2	3345	0.2
chr17_81386388_81386573	0.36	Gm50044	predicted gene, 50044	15647	0.24
chr7_99132344_99132620	0.36	Uvrag	UV radiation resistance associated gene	8636	0.13
chr11_11960671_11960874	0.36	Grb10	growth factor receptor bound protein 10	4748	0.24
chr8_122047070_122047266	0.36	Banp	BTG3 associated nuclear protein	46321	0.11
chr6_116208623_116208898	0.36	Washc2	WASH complex subunit 2`	244	0.79
chr18_39437876_39438027	0.36	Gm15337	predicted gene 15337	48526	0.13
chr13_9057691_9057882	0.35	Gm36264	predicted gene, 36264	18665	0.13
chr5_9108773_9108929	0.35	Tmem243	transmembrane protein 243, mitochondrial	4397	0.19
chr7_19701985_19702180	0.35	Tomm40	translocase of outer mitochondrial membrane 40	1058	0.26
chr4_76485956_76486132	0.35	Gm42303	predicted gene, 42303	34813	0.18
chr10_87523673_87523889	0.35	Pah	phenylalanine hydroxylase	1754	0.37
chr3_152407292_152407443	0.34	Zzz3	zinc finger, ZZ domain containing 3	10673	0.11
chr6_108290766_108291042	0.34	Itpr1	inositol 1,4,5-trisphosphate receptor 1	37946	0.19
chr12_84328286_84328437	0.34	Zfp410	zinc finger protein 410	921	0.43
chr15_38068899_38069087	0.34	Ubr5	ubiquitin protein ligase E3 component n-recognin 5	9432	0.15
chr4_99046002_99046218	0.34	Dock7	dedicator of cytokinesis 7	9223	0.18
chr9_122849425_122849576	0.34	Gm47140	predicted gene, 47140	1082	0.34
chr2_92424553_92424704	0.34	Cry2	cryptochrome 2 (photolyase-like)	7764	0.11
chr9_65748739_65748890	0.34	Zfp609	zinc finger protein 609	47670	0.11
chr6_24210867_24211018	0.33	Slc13a1	solute carrier family 13 (sodium/sulfate symporters), member 1	42850	0.16
chr15_68363065_68363728	0.33	Gm20732	predicted gene 20732	220	0.9
chr1_88024764_88024940	0.33	Gm15375	predicted gene 15375	359	0.71
chr12_32822209_32822364	0.33	Nampt	nicotinamide phosphoribosyltransferase	1485	0.44
chrX_77496822_77496989	0.33	Tbl1x	transducin (beta)-like 1 X-linked	14108	0.22
chr1_190171694_190171885	0.33	Prox1	prospero homeobox 1	1075	0.41
chr13_52979915_52980103	0.33	Nfil3	nuclear factor, interleukin 3, regulated	1064	0.5
chr1_67192197_67192413	0.33	Gm15668	predicted gene 15668	56895	0.12
chr10_93884020_93884171	0.33	Metap2	methionine aminopeptidase 2	3391	0.17
chr6_82053565_82053903	0.33	Gm15864	predicted gene 15864	1153	0.38
chr16_20715133_20715551	0.33	Clcn2	chloride channel, voltage-sensitive 2	769	0.38
chr5_36621044_36621360	0.32	D5Ertd579e	DNA segment, Chr 5, ERATO Doi 579, expressed	53	0.96
chr1_9744946_9745115	0.32	1700034P13Rik	RIKEN cDNA 1700034P13 gene	2618	0.2
chr17_28429327_28429723	0.32	Fkbp5	FK506 binding protein 5	896	0.41
chr2_146555306_146555646	0.32	4933406D12Rik	RIKEN cDNA 4933406D12 gene	12545	0.25
chr17_26589554_26589705	0.32	Ergic1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	5247	0.13
chr3_130059270_130059430	0.32	Sec24b	Sec24 related gene family, member B (S. cerevisiae)	1557	0.34
chr8_77199905_77200064	0.32	Gm23260	predicted gene, 23260	5289	0.24
chr2_63925859_63926184	0.32	Fign	fidgetin	171967	0.04
chr13_44430370_44430571	0.32	1700029N11Rik	RIKEN cDNA 1700029N11 gene	9242	0.15
chr13_64205035_64205186	0.31	Cdc14b	CDC14 cell division cycle 14B	4072	0.13
chr9_106235366_106235517	0.31	Alas1	aminolevulinic acid synthase 1	1643	0.22
chr15_25714947_25715172	0.31	Myo10	myosin X	1188	0.53
chr18_64484966_64485209	0.31	Fech	ferrochelatase	3854	0.19
chr3_89113405_89113607	0.31	Gm29704	predicted gene, 29704	3218	0.1
chr11_11845100_11845416	0.30	Ddc	dopa decarboxylase	8978	0.18
chr8_93258499_93258650	0.30	Ces1f	carboxylesterase 1F	165	0.94
chr3_52011173_52011324	0.30	Gm37465	predicted gene, 37465	7223	0.13
chr19_8735955_8736119	0.30	Wdr74	WD repeat domain 74	155	0.8
chr14_48058567_48058745	0.30	Gm49306	predicted gene, 49306	11645	0.15
chr6_51578097_51578258	0.30	Snx10	sorting nexin 10	33611	0.16
chr14_59084522_59084678	0.30	Gm48453	predicted gene, 48453	2518	0.26
chr5_130019586_130019737	0.30	Asl	argininosuccinate lyase	4639	0.13
chr15_59032105_59032256	0.29	Mtss1	MTSS I-BAR domain containing 1	8416	0.21
chr2_52576598_52576771	0.29	Cacnb4	calcium channel, voltage-dependent, beta 4 subunit	18117	0.18
chr13_44445691_44446120	0.29	Gm27036	predicted gene, 27036	6092	0.16
chr2_31477347_31478122	0.29	Ass1	argininosuccinate synthetase 1	7527	0.19
chr5_23418501_23419033	0.29	5031425E22Rik	RIKEN cDNA 5031425E22 gene	14542	0.12
chr5_139362838_139363176	0.29	Mir339	microRNA 339	6738	0.11
chr7_29247733_29248167	0.29	2200002D01Rik	RIKEN cDNA 2200002D01 gene	388	0.72
chr5_125513670_125513845	0.29	Aacs	acetoacetyl-CoA synthetase	440	0.79
chr4_117125610_117126073	0.29	Btbd19	BTB (POZ) domain containing 19	116	0.86
chr18_25554784_25554942	0.29	Gm3227	predicted gene 3227	42627	0.17
chr3_15201420_15201600	0.29	Gm33819	predicted gene, 33819	30068	0.23
chr3_145560024_145560207	0.29	Col24a1	collagen, type XXIV, alpha 1	15142	0.19
chr4_104846208_104846359	0.29	C8a	complement component 8, alpha polypeptide	10240	0.19
chr4_116703446_116704003	0.28	Mmachc	methylmalonic aciduria cblC type, with homocystinuria	4564	0.12
chr10_50657463_50657625	0.28	Ascc3	activating signal cointegrator 1 complex subunit 3	8489	0.23
chr13_95828416_95828713	0.28	Iqgap2	IQ motif containing GTPase activating protein 2	63193	0.1
chr14_32162147_32162298	0.28	Ncoa4	nuclear receptor coactivator 4	2241	0.18
chr5_104471233_104471571	0.28	Pkd2	polycystin 2, transient receptor potential cation channel	11832	0.16
chr15_79074715_79074866	0.28	Eif3l	eukaryotic translation initiation factor 3, subunit L	389	0.68
chr11_16819865_16820197	0.28	Egfros	epidermal growth factor receptor, opposite strand	10671	0.22
chr14_11801019_11801346	0.28	Gm48602	predicted gene, 48602	33239	0.19
chr9_64281484_64281643	0.28	Tipin	timeless interacting protein	18	0.96
chr7_19664934_19665237	0.28	Clptm1	cleft lip and palate associated transmembrane protein 1	52	0.93
chr12_71368459_71368708	0.27	Gm40438	predicted gene, 40438	13142	0.15
chr1_30940456_30940607	0.27	Ptp4a1	protein tyrosine phosphatase 4a1	3773	0.2
chr19_10077162_10077329	0.27	Fads2	fatty acid desaturase 2	6058	0.15
chr11_87702293_87702667	0.27	1110028F11Rik	RIKEN cDNA 1110028F11 gene	357	0.76
chr17_26719114_26719268	0.27	Crebrf	CREB3 regulatory factor	3467	0.2
chr18_62095425_62095728	0.27	Gm41750	predicted gene, 41750	47042	0.14
chr2_58785851_58786309	0.27	Upp2	uridine phosphorylase 2	20755	0.19
chr18_74931662_74931813	0.27	Gm18786	predicted gene, 18786	4543	0.12
chr11_77788021_77788193	0.27	Gm10277	predicted gene 10277	360	0.83
chr1_74028158_74028331	0.27	Tns1	tensin 1	8889	0.23
chr4_141559216_141559981	0.26	B330016D10Rik	RIKEN cDNA B330016D10 gene	13409	0.12
chr4_106580992_106581506	0.26	Gm12744	predicted gene 12744	7859	0.11
chr9_21688894_21689087	0.26	Gm26511	predicted gene, 26511	34460	0.09
chr7_89404848_89405054	0.26	Fzd4	frizzled class receptor 4	596	0.47
chr14_45378763_45379131	0.26	Gnpnat1	glucosamine-phosphate N-acetyltransferase 1	4496	0.14
chr7_45615310_45615638	0.26	Fgf21	fibroblast growth factor 21	16	0.91
chr5_24931562_24931772	0.26	Prkag2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	22690	0.15
chr17_56051343_56051500	0.26	Chaf1a	chromatin assembly factor 1, subunit A (p150)	4607	0.1
chr9_121677553_121677957	0.26	Vipr1	vasoactive intestinal peptide receptor 1	9042	0.11
chr2_3335831_3335993	0.25	Acbd7	acyl-Coenzyme A binding domain containing 7	256	0.87
chr2_58758962_58759113	0.25	Upp2	uridine phosphorylase 2	3825	0.24
chr2_162989615_162989976	0.25	Sgk2	serum/glucocorticoid regulated kinase 2	2293	0.2
chr2_72157539_72157839	0.25	Rapgef4os1	Rap guanine nucleotide exchange factor (GEF) 4, opposite strand 1	8893	0.2
chr17_28702072_28702269	0.25	Mapk14	mitogen-activated protein kinase 14	9602	0.12
chr15_85742021_85742427	0.25	Ppara	peroxisome proliferator activated receptor alpha	6093	0.16
chr19_60589967_60590189	0.25	Cacul1	CDK2 associated, cullin domain 1	9053	0.18
chr11_43170710_43170884	0.25	Atp10b	ATPase, class V, type 10B	15126	0.2
chr16_32896347_32896498	0.25	Fyttd1	forty-two-three domain containing 1	1331	0.34
chr13_81332008_81332361	0.25	Adgrv1	adhesion G protein-coupled receptor V1	10652	0.27
chr4_116450268_116450448	0.25	Gm12950	predicted gene 12950	1570	0.34
chr2_30981826_30982365	0.25	BC005624	cDNA sequence BC005624	106	0.61
chr4_102557092_102557428	0.25	Pde4b	phosphodiesterase 4B, cAMP specific	12835	0.29
chr13_41199632_41199844	0.25	Elovl2	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2	20424	0.11
chr16_41258426_41258587	0.25	Gm47276	predicted gene, 47276	40729	0.18
chr1_84826270_84826425	0.25	Gm37738	predicted gene, 37738	1664	0.29

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Mga

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.2	0.5	GO:0010046	response to mycotoxin(GO:0010046)
0.1	1.2	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1	0.3	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.1	0.3	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.1	0.4	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.2	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1	0.2	GO:0060178	regulation of exocyst localization(GO:0060178)
0.1	0.2	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.1	0.3	GO:0048478	replication fork protection(GO:0048478)
0.1	0.5	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.1	0.2	GO:0060375	regulation of mast cell differentiation(GO:0060375)
0.0	0.4	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857)
0.0	0.2	GO:0070535	histone H2A K63-linked ubiquitination(GO:0070535)
0.0	0.4	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.1	GO:0072361	regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0	0.1	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0	0.2	GO:0070126	mitochondrial translational termination(GO:0070126)
0.0	0.2	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.2	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.0	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.2	GO:0060613	fat pad development(GO:0060613)
0.0	0.1	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.1	GO:0035973	aggrephagy(GO:0035973)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:1901162	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0	0.1	GO:0034287	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.2	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.1	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0	0.1	GO:1902226	regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.0	0.1	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.0	0.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.1	GO:0021603	cranial nerve formation(GO:0021603)
0.0	0.0	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
0.0	0.2	GO:0021540	corpus callosum morphogenesis(GO:0021540)
0.0	0.1	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.1	GO:0001827	inner cell mass cell fate commitment(GO:0001827)
0.0	0.1	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	0.1	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.1	GO:1990168	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	0.1	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.1	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.0	0.1	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.1	GO:0048769	sarcomerogenesis(GO:0048769)
0.0	0.2	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0	0.1	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0	0.1	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.0	0.1	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.2	GO:0099515	actin filament-based transport(GO:0099515)
0.0	0.1	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.0	0.2	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.0	0.1	GO:2000468	regulation of peroxidase activity(GO:2000468)
0.0	0.1	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0	0.1	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.1	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.0	0.1	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.0	0.1	GO:0042723	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0	0.1	GO:0010424	DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776)
0.0	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.1	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	0.1	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.0	0.1	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.1	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0	0.0	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.0	0.1	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.1	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.0	0.1	GO:0003186	tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195)
0.0	0.1	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0	0.1	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0045196	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0	0.1	GO:0097343	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0	0.1	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.0	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.1	GO:0034756	regulation of iron ion transport(GO:0034756)
0.0	0.1	GO:0038171	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0	0.1	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
0.0	0.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.1	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.1	GO:1903797	positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0	0.1	GO:0045046	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0	0.1	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.1	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.1	GO:0072566	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0	0.1	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.0	0.1	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.1	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.0	0.1	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.6	GO:0070542	response to fatty acid(GO:0070542)
0.0	0.1	GO:0036233	glycine import(GO:0036233)
0.0	0.1	GO:0098535	de novo centriole assembly(GO:0098535)
0.0	0.0	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0	0.1	GO:0042148	strand invasion(GO:0042148)
0.0	0.1	GO:0046984	regulation of hemoglobin biosynthetic process(GO:0046984)
0.0	0.0	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.0	0.0	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.0	GO:0035459	cargo loading into vesicle(GO:0035459)
0.0	0.3	GO:0017144	drug metabolic process(GO:0017144)
0.0	0.0	GO:0009212	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0	0.0	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.1	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.4	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.0	GO:0002159	desmosome assembly(GO:0002159)
0.0	0.0	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.1	GO:0061032	visceral serous pericardium development(GO:0061032)
0.0	0.1	GO:1903242	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0	0.2	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.0	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.0	0.1	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.0	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.0	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.0	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336)
0.0	0.1	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.0	0.1	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.2	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.0	GO:0021553	olfactory nerve development(GO:0021553)
0.0	0.0	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.0	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.0	0.0	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
0.0	0.1	GO:0046146	tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.0	0.0	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
0.0	0.0	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.0	GO:0046271	phenylpropanoid metabolic process(GO:0009698) phenylpropanoid catabolic process(GO:0046271)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
0.0	0.0	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
0.0	0.0	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0	0.1	GO:0010992	ubiquitin homeostasis(GO:0010992)
0.0	0.0	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.1	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.0	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.1	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.2	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.0	GO:2000847	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0	0.0	GO:0060331	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.1	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.0	GO:0044821	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.1	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.0	GO:0090135	actin filament branching(GO:0090135)
0.0	0.1	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.0	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	0.0	GO:1990928	response to amino acid starvation(GO:1990928)
0.0	0.1	GO:0052696	flavonoid biosynthetic process(GO:0009813) flavonoid glucuronidation(GO:0052696)
0.0	0.1	GO:0000059	protein import into nucleus, docking(GO:0000059)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.4	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.6	GO:0070852	cell body fiber(GO:0070852)
0.1	0.2	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.2	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.3	GO:0001650	fibrillar center(GO:0001650)
0.0	0.1	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.2	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0097413	Lewy body(GO:0097413)
0.0	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.0	0.2	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.1	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.1	GO:0031417	NatC complex(GO:0031417)
0.0	0.2	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0098536	deuterosome(GO:0098536)
0.0	0.1	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	1.3	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.0	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.0	0.1	GO:0031209	SCAR complex(GO:0031209)
0.0	0.1	GO:0045180	basal cortex(GO:0045180)
0.0	0.1	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.0	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
0.0	0.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.0	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.6	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.0	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.1	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.1	GO:0046930	pore complex(GO:0046930)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520)
0.0	0.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.0	0.1	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.0	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.0	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.3	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.0	GO:1990635	proximal dendrite(GO:1990635)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.1	GO:0043426	MRF binding(GO:0043426)
0.1	0.6	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.1	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.2	GO:0004771	sterol esterase activity(GO:0004771)
0.1	0.2	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.6	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.2	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.7	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.0	0.2	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.2	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.0	0.3	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.1	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.2	GO:0045322	unmethylated CpG binding(GO:0045322)
0.0	0.0	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.7	GO:0010296	prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	0.1	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0	0.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.2	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.2	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.1	GO:0000150	recombinase activity(GO:0000150)
0.0	0.0	GO:0045503	dynein light chain binding(GO:0045503)
0.0	0.1	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.3	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0	0.1	GO:0035671	enone reductase activity(GO:0035671)
0.0	0.1	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.2	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.0	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.0	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.3	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.0	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.0	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.0	GO:0035939	microsatellite binding(GO:0035939)
0.0	0.0	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.0	0.0	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.2	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.0	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.6	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.0	0.0	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.0	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.0	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.2	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.3	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.0	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.0	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.0	0.0	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.1	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.4	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.5	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.2	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.7	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	1.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.5	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.4	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.1	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.3	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.1	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts