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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Mnx1_Lhx6_Lmx1a

Z-value: 1.38

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Transcription factors associated with Mnx1_Lhx6_Lmx1a

Gene Symbol	Gene ID	Gene Info
Mnx1 Ensembl NCBI MGI UniProt	ENSMUSG00000001566.8	motor neuron and pancreas homeobox 1
Lhx6 Ensembl NCBI MGI UniProt	ENSMUSG00000026890.13	LIM homeobox protein 6
Lmx1a Ensembl NCBI MGI UniProt	ENSMUSG00000026686.8	LIM homeobox transcription factor 1 alpha

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_36091025_36091199	Lhx6	3161	0.170709	-0.90	1.3e-02	Click!
chr2_36091235_36091637	Lhx6	2837	0.181193	-0.87	2.6e-02	Click!
chr2_36092832_36093004	Lhx6	1355	0.326939	-0.82	4.5e-02	Click!
chr2_36082178_36082681	Lhx6	11844	0.122244	-0.81	5.3e-02	Click!
chr2_36084858_36085009	Lhx6	9340	0.126705	-0.63	1.8e-01	Click!
chr1_167755293_167755461	Lmx1a	65820	0.133270	0.86	2.9e-02	Click!
chr1_167760424_167760606	Lmx1a	70958	0.122781	-0.71	1.1e-01	Click!
chr1_167687774_167687925	Lmx1a	1388	0.552637	0.41	4.2e-01	Click!
chr1_167669885_167670043	Lmx1a	19273	0.237195	-0.24	6.5e-01	Click!
chr1_167746804_167746963	Lmx1a	57326	0.152713	0.13	8.0e-01	Click!

Activity of the Mnx1_Lhx6_Lmx1a motif across conditions

Conditions sorted by the z-value of the Mnx1_Lhx6_Lmx1a motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_125526040_125526191	2.95	Tmem132b	transmembrane protein 132B	5659	0.17
chr11_16883025_16883203	2.38	Egfr	epidermal growth factor receptor	4964	0.23
chr19_40153747_40153898	2.29	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	33464	0.13
chr17_80022007_80022158	2.14	Gm22215	predicted gene, 22215	11432	0.14
chr12_51274477_51274668	2.08	Rps11-ps4	ribosomal protein S11, pseudogene 4	22915	0.22
chr17_46054574_46054727	2.07	Vegfa	vascular endothelial growth factor A	22281	0.12
chr1_100298746_100298897	2.00	Gm29667	predicted gene 29667	16030	0.18
chr3_18151456_18151607	1.95	Gm23686	predicted gene, 23686	26094	0.2
chr11_16854059_16854210	1.91	Egfros	epidermal growth factor receptor, opposite strand	23432	0.17
chr7_140722780_140722931	1.84	Olfr542-ps1	olfactory receptor 542, pseudogene 1	1573	0.22
chr1_21252081_21252232	1.79	Gsta3	glutathione S-transferase, alpha 3	1365	0.29
chr19_44400352_44400581	1.78	Scd1	stearoyl-Coenzyme A desaturase 1	6224	0.15
chr12_57537784_57538085	1.77	Foxa1	forkhead box A1	8187	0.15
chr2_14596063_14596214	1.70	Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	6950	0.13
chr9_74885383_74885534	1.61	Onecut1	one cut domain, family member 1	18974	0.14
chr16_87627804_87628113	1.57	Gm22808	predicted gene, 22808	6838	0.21
chr16_18071409_18071560	1.56	Dgcr6	DiGeorge syndrome critical region gene 6	2004	0.23
chr19_44401346_44401497	1.54	Scd1	stearoyl-Coenzyme A desaturase 1	5269	0.16
chr4_44777019_44777170	1.53	Zcchc7	zinc finger, CCHC domain containing 7	16650	0.16
chr2_4895477_4895652	1.48	Sephs1	selenophosphate synthetase 1	11180	0.15
chr10_87932167_87932318	1.47	Tyms-ps	thymidylate synthase, pseudogene	34605	0.14
chr10_62592617_62592774	1.45	Ddx21	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21	1724	0.23
chr9_74328635_74328791	1.40	Gm24141	predicted gene, 24141	33897	0.17
chr10_4618620_4618773	1.37	Esr1	estrogen receptor 1 (alpha)	6675	0.25
chr2_58787332_58787483	1.34	Upp2	uridine phosphorylase 2	22082	0.19
chr9_106264996_106265377	1.32	Poc1a	POC1 centriolar protein A	15875	0.1
chr2_18048778_18049088	1.31	Skida1	SKI/DACH domain containing 1	98	0.94
chr19_56521472_56521623	1.29	Dclre1a	DNA cross-link repair 1A	15835	0.17
chr19_44401904_44402310	1.29	Scd1	stearoyl-Coenzyme A desaturase 1	4583	0.17
chr12_104341895_104342090	1.27	Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	3506	0.14
chr2_73628966_73629117	1.27	Chn1	chimerin 1	3301	0.21
chr10_24362567_24362800	1.27	Gm15271	predicted gene 15271	84807	0.08
chr3_18164974_18165125	1.27	Gm23686	predicted gene, 23686	12576	0.23
chr3_18163689_18163955	1.26	Gm23686	predicted gene, 23686	13803	0.23
chr14_30530847_30531018	1.23	Dcp1a	decapping mRNA 1A	7225	0.15
chr11_16843001_16843162	1.22	Egfros	epidermal growth factor receptor, opposite strand	12379	0.2
chr4_109104769_109104920	1.20	Osbpl9	oxysterol binding protein-like 9	3187	0.27
chr2_107628721_107628872	1.20	Gm9864	predicted gene 9864	28257	0.26
chr8_105090981_105091315	1.19	Ces3b	carboxylesterase 3B	2529	0.16
chr9_74884431_74884582	1.18	Onecut1	one cut domain, family member 1	18022	0.15
chr1_124069161_124069328	1.17	Dpp10	dipeptidylpeptidase 10	23685	0.27
chr7_68285442_68285612	1.15	Gm16157	predicted gene 16157	8933	0.14
chr16_42947764_42948084	1.14	Ndufs5-ps	NADH:ubiquinone oxidoreductase core subunit S5, pseudogene	7707	0.21
chr8_94394237_94394701	1.12	Herpud1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	938	0.39
chr4_40698726_40698877	1.12	Aptx	aprataxin	3915	0.15
chr19_37507552_37507703	1.11	Exoc6	exocyst complex component 6	13252	0.16
chr3_133759501_133760150	1.10	Gm6135	prediticted gene 6135	31679	0.18
chr7_115858420_115858571	1.09	Sox6	SRY (sex determining region Y)-box 6	1357	0.57
chr17_64607771_64607970	1.05	Man2a1	mannosidase 2, alpha 1	7134	0.26
chr4_123990393_123990580	1.04	Gm12902	predicted gene 12902	64252	0.08
chr14_20116129_20116316	1.04	Saysd1	SAYSVFN motif domain containing 1	22312	0.14
chr8_93190868_93191185	1.03	Gm45909	predicted gene 45909	332	0.84
chr6_51695515_51695666	1.03	Gm38811	predicted gene, 38811	15491	0.23
chr9_74791015_74791321	1.01	Gm22315	predicted gene, 22315	9098	0.19
chr1_67162712_67162908	0.99	Cps1	carbamoyl-phosphate synthetase 1	39784	0.16
chr9_122118490_122118656	0.97	Gm47122	predicted gene, 47122	572	0.49
chr7_135720125_135720308	0.97	Mki67	antigen identified by monoclonal antibody Ki 67	3855	0.2
chr10_87870357_87870520	0.97	Igf1os	insulin-like growth factor 1, opposite strand	7057	0.21
chr9_60982764_60983106	0.96	Gm5122	predicted gene 5122	30546	0.14
chr5_86919547_86919811	0.96	Gm25211	predicted gene, 25211	3357	0.13
chr1_84993315_84993466	0.96	Gm29284	predicted gene 29284	358	0.79
chr12_33285610_33285770	0.95	Atxn7l1	ataxin 7-like 1	16825	0.2
chr3_138282244_138282429	0.95	Adh1	alcohol dehydrogenase 1 (class I)	4685	0.14
chr8_38604147_38604298	0.94	Gm40493	predicted gene, 40493	55541	0.14
chr3_118592277_118592428	0.94	Dpyd	dihydropyrimidine dehydrogenase	30166	0.17
chr8_110644559_110644860	0.94	Vac14	Vac14 homolog (S. cerevisiae)	871	0.63
chr13_44437957_44438156	0.93	1700029N11Rik	RIKEN cDNA 1700029N11 gene	1656	0.27
chr2_13522226_13522421	0.93	Trdmt1	tRNA aspartic acid methyltransferase 1	22327	0.19
chr16_65665507_65665824	0.92	Gm49633	predicted gene, 49633	52246	0.14
chr2_64093669_64093820	0.91	Fign	fidgetin	4244	0.37
chr1_88055296_88055515	0.90	Ugt1a10	UDP glycosyltransferase 1 family, polypeptide A10	6	0.94
chr19_55110942_55111169	0.90	Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	7964	0.2
chr7_132953914_132954065	0.89	Zranb1	zinc finger, RAN-binding domain containing 1	4405	0.17
chr7_65902304_65902456	0.89	Pcsk6	proprotein convertase subtilisin/kexin type 6	39948	0.14
chr4_19713524_19713754	0.88	Wwp1	WW domain containing E3 ubiquitin protein ligase 1	4646	0.23
chr11_32651005_32651314	0.88	Fbxw11	F-box and WD-40 domain protein 11	8255	0.23
chrX_72953520_72953708	0.88	Nsdhl	NAD(P) dependent steroid dehydrogenase-like	23862	0.1
chr11_16761103_16761540	0.87	Egfr	epidermal growth factor receptor	9091	0.2
chr15_3721208_3721477	0.87	Gm4823	predicted gene 4823	25533	0.23
chr12_83926450_83926603	0.86	Numb	NUMB endocytic adaptor protein	4592	0.13
chr7_67648192_67648343	0.86	Ttc23	tetratricopeptide repeat domain 23	807	0.52
chr5_92607049_92607221	0.86	Stbd1	starch binding domain 1	4067	0.19
chr4_126764112_126764263	0.85	AU040320	expressed sequence AU040320	10361	0.13
chr19_31886956_31887132	0.85	A1cf	APOBEC1 complementation factor	18263	0.2
chr2_38823684_38823849	0.85	Nr6a1os	nuclear receptor subfamily 6, group A, member 1, opposite strand	425	0.74
chr8_114156887_114157038	0.85	Nudt7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	23320	0.23
chr4_101198122_101198415	0.84	Gm24468	predicted gene, 24468	11504	0.14
chr13_24360335_24360523	0.84	Gm11342	predicted gene 11342	15521	0.12
chr6_37870282_37871066	0.84	Trim24	tripartite motif-containing 24	137	0.96
chr16_78470224_78470428	0.83	Gm49603	predicted gene, 49603	10213	0.17
chr14_21095037_21095192	0.83	Adk	adenosine kinase	18962	0.21
chr9_46479855_46480133	0.83	Gm47144	predicted gene, 47144	25079	0.15
chr3_69280240_69280391	0.83	Ppm1l	protein phosphatase 1 (formerly 2C)-like	36546	0.13
chr16_13359323_13359477	0.82	Mrtfb	myocardin related transcription factor B	979	0.59
chr2_72210584_72210735	0.82	Rapgef4	Rap guanine nucleotide exchange factor (GEF) 4	11860	0.17
chr8_90953750_90953901	0.82	Chd9	chromodomain helicase DNA binding protein 9	1133	0.47
chr3_60525375_60525543	0.82	Mbnl1	muscleblind like splicing factor 1	2669	0.31
chr13_52979672_52979858	0.82	Nfil3	nuclear factor, interleukin 3, regulated	1308	0.43
chr18_75498893_75499229	0.82	Gm10532	predicted gene 10532	15584	0.25
chr13_63665698_63665976	0.82	Gm47387	predicted gene, 47387	4040	0.18
chr14_18369164_18369315	0.81	Ube2e1	ubiquitin-conjugating enzyme E2E 1	37380	0.15
chr18_51150358_51150691	0.81	Prr16	proline rich 16	32786	0.23
chr12_83905337_83905488	0.80	Numb	NUMB endocytic adaptor protein	16321	0.11
chr18_55794167_55794318	0.80	Gm8614	predicted gene 8614	44707	0.14
chr15_59002495_59002896	0.80	4930544F09Rik	RIKEN cDNA 4930544F09 gene	18559	0.16
chr12_73341772_73342027	0.80	Slc38a6	solute carrier family 38, member 6	2468	0.25
chr15_53238274_53238425	0.80	Ext1	exostosin glycosyltransferase 1	42094	0.21
chr4_136470355_136470864	0.80	Luzp1	leucine zipper protein 1	759	0.6
chr14_21295488_21295639	0.79	Adk	adenosine kinase	22562	0.24
chr6_52610697_52610915	0.79	Gm44434	predicted gene, 44434	7561	0.15
chr10_54072535_54072686	0.79	Man1a	mannosidase 1, alpha	3099	0.23
chr10_116968969_116969126	0.79	D630029K05Rik	RIKEN cDNA D630029K05 gene	2773	0.15
chr9_64175252_64175472	0.79	Snord16a	small nucleolar RNA, C/D box 16A	61	0.7
chr4_15212980_15213172	0.79	Tmem64	transmembrane protein 64	52755	0.13
chr17_17375909_17376093	0.78	Riok2	RIO kinase 2	1411	0.29
chr2_24040580_24040761	0.78	Hnmt	histamine N-methyltransferase	8196	0.23
chr7_67578755_67579151	0.77	Lrrc28	leucine rich repeat containing 28	797	0.57
chr1_51740463_51740849	0.77	Gm28055	predicted gene 28055	6287	0.22
chr11_120810774_120811098	0.77	Fasn	fatty acid synthase	1235	0.26
chr9_80672553_80672726	0.76	Gm39380	predicted gene, 39380	37356	0.19
chr10_8642393_8642547	0.76	Gm24374	predicted gene, 24374	464	0.87
chr2_28618402_28618756	0.76	Gfi1b	growth factor independent 1B	3174	0.15
chr4_135255267_135255418	0.76	Clic4	chloride intracellular channel 4 (mitochondrial)	17472	0.14
chr16_10675930_10676129	0.76	Gm15558	predicted gene 15558	7510	0.18
chr4_134814659_134814853	0.76	Maco1	macoilin 1	3543	0.24
chr2_18063532_18063683	0.76	Mllt10	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10	787	0.48
chr5_99976807_99976958	0.76	Hnrnpd	heterogeneous nuclear ribonucleoprotein D	331	0.73
chr3_131485378_131485553	0.74	Sgms2	sphingomyelin synthase 2	5014	0.28
chr2_73608857_73609047	0.74	Chn1os3	chimerin 1, opposite strand 3	12128	0.14
chr4_123990670_123991070	0.74	Gm12902	predicted gene 12902	64636	0.08
chr1_63136268_63136443	0.74	Ndufs1	NADH:ubiquinone oxidoreductase core subunit S1	8606	0.09
chr19_38339776_38339993	0.73	Gm50150	predicted gene, 50150	2730	0.22
chr1_127775248_127775429	0.73	Ccnt2	cyclin T2	1174	0.34
chr12_75531904_75532183	0.72	Ppp2r5e	protein phosphatase 2, regulatory subunit B', epsilon	17631	0.18
chr8_46908148_46908299	0.72	1700011L03Rik	RIKEN cDNA 1700011L03 gene	40576	0.13
chr6_144895356_144895507	0.71	Gm22792	predicted gene, 22792	91799	0.07
chr2_122251200_122251358	0.71	Sord	sorbitol dehydrogenase	16530	0.1
chr4_53221393_53221544	0.71	4930412L05Rik	RIKEN cDNA 4930412L05 gene	3611	0.22
chr13_96667373_96667613	0.71	Hmgcr	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	730	0.61
chr16_11109338_11109489	0.70	Txndc11	thioredoxin domain containing 11	13324	0.1
chr10_19464719_19464880	0.70	Gm33104	predicted gene, 33104	21916	0.2
chr4_45461496_45461674	0.70	Shb	src homology 2 domain-containing transforming protein B	21217	0.14
chr6_42370505_42370669	0.70	2010310C07Rik	RIKEN cDNA 2010310C07 gene	84	0.93
chr15_53169203_53169532	0.70	Ext1	exostosin glycosyltransferase 1	26888	0.27
chr15_59040377_59040733	0.70	Mtss1	MTSS I-BAR domain containing 1	41	0.98
chr13_37854787_37854958	0.69	Rreb1	ras responsive element binding protein 1	3062	0.27
chr18_33351785_33351948	0.69	Gm5503	predicted gene 5503	33089	0.21
chrX_38400123_38400274	0.69	Gm4853	predicted pseudogene 4853	3263	0.22
chr8_114153359_114153564	0.69	Nudt7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	19819	0.24
chr2_158341832_158341983	0.68	Gm24411	predicted gene, 24411	14647	0.08
chr11_61270260_61270411	0.68	Aldh3a2	aldehyde dehydrogenase family 3, subfamily A2	2871	0.23
chr3_144446211_144446394	0.67	Gm5857	predicted gene 5857	18630	0.18
chr1_67227292_67227476	0.67	Gm15668	predicted gene 15668	21816	0.2
chr1_102517589_102517767	0.67	Gm20281	predicted gene, 20281	58756	0.14
chr15_64267279_64267461	0.67	Asap1	ArfGAP with SH3 domain, ankyrin repeat and PH domain1	44319	0.14
chr5_33465562_33465766	0.67	Gm43851	predicted gene 43851	28200	0.15
chr2_154827673_154827835	0.66	Raly	hnRNP-associated with lethal yellow	36039	0.12
chr3_118443694_118443845	0.66	Gm9916	predicted gene 9916	8999	0.15
chr11_118508000_118508168	0.66	Rbfox3	RNA binding protein, fox-1 homolog (C. elegans) 3	731	0.62
chr5_122876895_122877046	0.66	Kdm2b	lysine (K)-specific demethylase 2B	4115	0.16
chr2_160865219_160865594	0.66	Zhx3	zinc fingers and homeoboxes 3	5775	0.14
chr8_44955232_44955417	0.65	Fat1	FAT atypical cadherin 1	5110	0.23
chr9_9194559_9194710	0.65	Gm16833	predicted gene, 16833	41654	0.17
chr19_10087853_10088030	0.64	Fads2	fatty acid desaturase 2	775	0.57
chr4_40729981_40730352	0.64	Dnaja1	DnaJ heat shock protein family (Hsp40) member A1	6117	0.12
chr5_62761138_62761503	0.64	Arap2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	4800	0.29
chr2_34049474_34049625	0.64	C230014O12Rik	RIKEN cDNA C230014O12 gene	58180	0.11
chr7_70481551_70481951	0.64	Gm7656	predicted gene 7656	9097	0.15
chr7_43672420_43672601	0.64	Ctu1	cytosolic thiouridylase subunit 1	494	0.54
chr17_89646332_89646522	0.64	Gm50061	predicted gene, 50061	106099	0.08
chr14_21221949_21222133	0.63	Adk	adenosine kinase	96084	0.08
chr12_99371949_99372100	0.63	Gm47138	predicted gene, 47138	2111	0.22
chr6_67441579_67441755	0.63	Gm44083	predicted gene, 44083	23616	0.11
chr10_20723719_20723889	0.63	Pde7b	phosphodiesterase 7B	892	0.65
chr10_42230294_42230483	0.63	Foxo3	forkhead box O3	27978	0.22
chr10_87872347_87872727	0.62	Igf1os	insulin-like growth factor 1, opposite strand	9156	0.2
chr10_89563955_89564134	0.62	Gm48087	predicted gene, 48087	8325	0.2
chr11_58614498_58614839	0.62	2210407C18Rik	RIKEN cDNA 2210407C18 gene	1176	0.25
chr18_39438249_39438499	0.62	Nr3c1	nuclear receptor subfamily 3, group C, member 1	48858	0.13
chr16_72808058_72808236	0.62	Robo1	roundabout guidance receptor 1	144943	0.05
chr3_69115488_69115663	0.62	Gm37558	predicted gene, 37558	7149	0.14
chr6_72120521_72121047	0.62	4933431G14Rik	RIKEN cDNA 4933431G14 gene	2156	0.2
chr19_53904567_53904727	0.62	Pdcd4	programmed cell death 4	1231	0.39
chr3_18250842_18251072	0.61	Cyp7b1	cytochrome P450, family 7, subfamily b, polypeptide 1	7619	0.24
chr5_150918259_150918412	0.61	Kl	klotho	34272	0.15
chr11_22844106_22844418	0.61	Gm23772	predicted gene, 23772	2606	0.17
chr11_16758574_16758725	0.61	Egfr	epidermal growth factor receptor	6419	0.21
chr14_61687453_61687640	0.61	Gm37820	predicted gene, 37820	4036	0.12
chr17_74255165_74255351	0.61	Memo1	mediator of cell motility 1	727	0.62
chr5_90440158_90440365	0.60	Alb	albumin	20636	0.14
chr3_149234408_149234559	0.60	Gm10287	predicted gene 10287	8738	0.21
chr14_21435070_21435221	0.60	Gm25864	predicted gene, 25864	15329	0.19
chr4_108370151_108370302	0.60	Shisal2a	shisa like 2A	13123	0.13
chr17_81386211_81386362	0.60	Gm50044	predicted gene, 50044	15453	0.24
chr2_113578462_113578613	0.60	Gm13964	predicted gene 13964	74503	0.09
chr18_65154932_65155123	0.60	Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	707	0.74
chr9_41328613_41328764	0.59	Mir100hg	Mir100 Mirlet7a-2 Mir125b-1 cluster host gene	78	0.97
chr1_67222842_67222998	0.59	Gm15668	predicted gene 15668	26280	0.19
chr1_21250942_21251436	0.59	Gsta3	glutathione S-transferase, alpha 3	2332	0.18
chr15_38105734_38106027	0.58	Gm49312	predicted gene, 49312	26778	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Mnx1_Lhx6_Lmx1a

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.0	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.3	1.2	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.3	1.2	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.3	0.8	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.3	0.8	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.2	0.9	GO:0046449	creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.2	0.9	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2	0.7	GO:0006068	ethanol catabolic process(GO:0006068)
0.2	0.4	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.2	0.6	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2	0.6	GO:0097167	circadian regulation of translation(GO:0097167)
0.2	1.0	GO:0006526	arginine biosynthetic process(GO:0006526)
0.2	0.5	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2	0.7	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.2	0.5	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.2	0.5	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.1	0.6	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1	0.4	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	0.8	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1	0.4	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1	0.9	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.1	1.0	GO:0051657	maintenance of organelle location(GO:0051657)
0.1	0.3	GO:0006741	NADP biosynthetic process(GO:0006741)
0.1	0.1	GO:0018879	biphenyl metabolic process(GO:0018879)
0.1	0.4	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1	0.3	GO:0001827	inner cell mass cell fate commitment(GO:0001827)
0.1	0.3	GO:0019086	late viral transcription(GO:0019086)
0.1	0.3	GO:1905206	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1	0.4	GO:0090168	Golgi reassembly(GO:0090168)
0.1	0.3	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.1	0.3	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.1	0.3	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.1	0.3	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1	0.4	GO:0003099	positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1	0.3	GO:0070340	detection of bacterial lipopeptide(GO:0070340)
0.1	0.3	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.1	0.3	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1	0.6	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.1	0.1	GO:0032741	positive regulation of interleukin-18 production(GO:0032741)
0.1	0.9	GO:0009404	toxin metabolic process(GO:0009404)
0.1	0.2	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1	0.4	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.1	0.7	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.1	0.2	GO:0046552	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1	0.2	GO:0046104	thymidine metabolic process(GO:0046104)
0.1	0.3	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	0.3	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.1	0.2	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1	0.5	GO:0045908	negative regulation of vasodilation(GO:0045908)
0.1	0.2	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1	0.2	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	0.1	GO:1903232	melanosome assembly(GO:1903232)
0.1	0.2	GO:0032383	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1	0.4	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	0.2	GO:0071233	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.1	0.1	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.1	0.4	GO:0034227	tRNA thio-modification(GO:0034227)
0.1	0.2	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.1	0.2	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1	0.5	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.1	0.4	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1	0.6	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1	0.2	GO:0006562	proline catabolic process(GO:0006562)
0.1	0.2	GO:0003383	apical constriction(GO:0003383)
0.1	0.2	GO:0034436	glycoprotein transport(GO:0034436)
0.1	0.3	GO:1901524	regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.1	0.8	GO:0003334	keratinocyte development(GO:0003334)
0.1	0.2	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.1	0.2	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.1	0.1	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.1	0.5	GO:0046130	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.1	0.1	GO:1904339	negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1	0.2	GO:0006041	glucosamine metabolic process(GO:0006041)
0.1	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.1	GO:0035973	aggrephagy(GO:0035973)
0.1	0.3	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1	0.2	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1	0.2	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.1	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.1	GO:0009446	putrescine biosynthetic process(GO:0009446)
0.0	0.1	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.2	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	1.4	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.3	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0	0.1	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.2	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.3	GO:0006559	L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	0.3	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.1	GO:0030210	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0	0.0	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0	0.4	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.2	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.0	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	0.3	GO:0061042	vascular wound healing(GO:0061042)
0.0	0.4	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.3	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.3	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.1	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0	0.1	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.4	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.2	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.2	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.2	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.2	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.2	GO:0042737	drug catabolic process(GO:0042737)
0.0	0.3	GO:0001842	neural fold formation(GO:0001842)
0.0	0.1	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.1	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0	0.2	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.2	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.0	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.1	GO:0001907	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.3	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.1	GO:0090427	activation of meiosis(GO:0090427)
0.0	0.2	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.3	GO:0006266	DNA ligation(GO:0006266)
0.0	0.3	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
0.0	0.1	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.0	0.1	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.1	GO:0023041	neuronal signal transduction(GO:0023041)
0.0	0.7	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.0	0.1	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.1	GO:0072025	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0	0.0	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
0.0	0.1	GO:0044597	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.2	GO:1902969	mitotic DNA replication(GO:1902969)
0.0	0.1	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.2	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0	0.4	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.1	GO:0000430	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0	0.1	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.0	0.0	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.0	0.1	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.1	GO:0061010	gall bladder development(GO:0061010)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.3	GO:0006098	pentose-phosphate shunt(GO:0006098)
0.0	0.1	GO:0061144	alveolar secondary septum development(GO:0061144)
0.0	0.1	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.0	0.2	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.0	0.1	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0	0.2	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0	0.2	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.1	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0	0.1	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.2	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.1	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.0	0.4	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.2	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.1	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0	0.2	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.0	0.2	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.1	GO:0072592	oxygen metabolic process(GO:0072592)
0.0	0.1	GO:0006407	rRNA export from nucleus(GO:0006407)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.0	GO:0046084	adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.9	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.3	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.1	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.0	GO:0072361	regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0	0.1	GO:0048341	paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.0	0.1	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.2	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.1	GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.0	0.1	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.0	0.1	GO:0042045	epithelial fluid transport(GO:0042045)
0.0	0.1	GO:0038171	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.0	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.0	GO:0060751	branch elongation involved in mammary gland duct branching(GO:0060751)
0.0	0.3	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.3	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.2	GO:0048617	embryonic foregut morphogenesis(GO:0048617)
0.0	0.3	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.3	GO:0006353	DNA-templated transcription, termination(GO:0006353)
0.0	0.1	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0035977	protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0	0.1	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.1	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0	0.0	GO:0014016	neuroblast differentiation(GO:0014016)
0.0	0.3	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	0.1	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0	0.6	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.4	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.1	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	0.1	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.0	0.2	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.5	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.0	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.1	GO:0045852	pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0	0.1	GO:0019740	nitrogen utilization(GO:0019740)
0.0	0.3	GO:0043482	cellular pigment accumulation(GO:0043482)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:1900044	regulation of protein K63-linked ubiquitination(GO:1900044)
0.0	0.2	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0	0.1	GO:0061589	calcium activated phosphatidylserine scrambling(GO:0061589)
0.0	0.2	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	0.1	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.0	0.1	GO:1902369	negative regulation of RNA catabolic process(GO:1902369) negative regulation of mRNA catabolic process(GO:1902373)
0.0	0.2	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.1	GO:0035754	B cell chemotaxis(GO:0035754)
0.0	0.2	GO:0001845	phagolysosome assembly(GO:0001845)
0.0	0.2	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	0.0	GO:0090214	spongiotrophoblast layer developmental growth(GO:0090214)
0.0	0.3	GO:0045116	protein neddylation(GO:0045116)
0.0	0.0	GO:2000224	regulation of testosterone biosynthetic process(GO:2000224)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.1	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0	0.4	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0	0.1	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.0	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.2	GO:0035810	positive regulation of urine volume(GO:0035810)
0.0	0.1	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0	0.0	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.0	GO:0061218	negative regulation of mesonephros development(GO:0061218)
0.0	0.0	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.1	GO:0072092	ureteric bud invasion(GO:0072092)
0.0	0.1	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0	0.0	GO:0035963	response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0	0.1	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.7	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.0	0.1	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0	0.0	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336)
0.0	0.1	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0	0.0	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.1	GO:0090045	positive regulation of deacetylase activity(GO:0090045)
0.0	0.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.0	GO:0003130	BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) embryonic heart tube anterior/posterior pattern specification(GO:0035054) cell proliferation involved in mesonephros development(GO:0061209)
0.0	0.2	GO:0017144	drug metabolic process(GO:0017144)
0.0	0.0	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.0	GO:0097212	lysosomal membrane organization(GO:0097212)
0.0	0.1	GO:0070900	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0	0.0	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0	0.1	GO:0030575	nuclear body organization(GO:0030575)
0.0	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.0	GO:0033092	positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.0	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.0	0.1	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0	0.3	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.0	0.2	GO:0031063	regulation of histone deacetylation(GO:0031063)
0.0	0.1	GO:0061072	iris morphogenesis(GO:0061072)
0.0	0.1	GO:0030432	peristalsis(GO:0030432)
0.0	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.0	GO:0034756	regulation of iron ion transport(GO:0034756)
0.0	0.0	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.0	0.0	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.5	GO:0010799	regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.0	0.2	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.0	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.5	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.1	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.0	0.0	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.1	GO:1902414	protein localization to cell junction(GO:1902414)
0.0	0.2	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.0	0.2	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
0.0	0.3	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:2000172	regulation of branching morphogenesis of a nerve(GO:2000172)
0.0	0.1	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.0	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.0	0.3	GO:0003416	endochondral bone growth(GO:0003416)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.0	0.0	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.0	0.5	GO:0031018	endocrine pancreas development(GO:0031018)
0.0	0.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.1	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.0	GO:1900368	regulation of RNA interference(GO:1900368)
0.0	0.1	GO:1990001	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0	0.0	GO:0009629	response to gravity(GO:0009629)
0.0	0.0	GO:0060126	somatotropin secreting cell differentiation(GO:0060126)
0.0	0.0	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.0	0.1	GO:0031017	exocrine pancreas development(GO:0031017)
0.0	0.0	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.1	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.0	0.1	GO:0034398	telomere tethering at nuclear periphery(GO:0034398)
0.0	0.0	GO:0010159	specification of organ position(GO:0010159)
0.0	0.0	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0	0.1	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	0.1	GO:0042448	progesterone metabolic process(GO:0042448)
0.0	0.1	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.2	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0071420	cellular response to histamine(GO:0071420)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0	0.2	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.0	GO:0072203	cell proliferation involved in metanephros development(GO:0072203)
0.0	0.0	GO:0003415	chondrocyte hypertrophy(GO:0003415)
0.0	0.0	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0	0.0	GO:0060681	ureteric bud elongation(GO:0060677) branch elongation involved in ureteric bud branching(GO:0060681)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0	0.0	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.0	0.0	GO:2000389	regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.0	0.2	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.0	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.0	0.0	GO:1904749	regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0046416	D-amino acid metabolic process(GO:0046416)
0.0	0.0	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	0.1	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.0	GO:0048793	pronephros development(GO:0048793)
0.0	0.0	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.0	0.2	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.0	0.1	GO:1902965	regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0	0.1	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.1	GO:1904293	negative regulation of ERAD pathway(GO:1904293)
0.0	0.0	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.0	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.1	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0	0.0	GO:0015770	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.1	GO:0035865	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0	0.0	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.0	0.0	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0	0.1	GO:0002176	male germ cell proliferation(GO:0002176)
0.0	0.0	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0	0.0	GO:0072711	response to hydroxyurea(GO:0072710) cellular response to hydroxyurea(GO:0072711)
0.0	0.2	GO:0048821	erythrocyte development(GO:0048821)
0.0	0.0	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.0	0.0	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0	0.1	GO:0046033	AMP metabolic process(GO:0046033)
0.0	0.0	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	0.0	GO:0006382	adenosine to inosine editing(GO:0006382)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.2	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.0	GO:1903999	negative regulation of eating behavior(GO:1903999)
0.0	0.2	GO:0055070	copper ion homeostasis(GO:0055070)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.0	GO:0071455	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0	0.1	GO:0043486	histone exchange(GO:0043486)
0.0	0.0	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0	0.1	GO:0097264	self proteolysis(GO:0097264)
0.0	0.0	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.2	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.0	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
0.0	0.0	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.0	0.2	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.0	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.0	GO:2000680	regulation of rubidium ion transport(GO:2000680) regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.0	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.0	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
0.0	0.1	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.1	GO:1990173	protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0	0.0	GO:2000303	regulation of ceramide biosynthetic process(GO:2000303)
0.0	0.0	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0	0.0	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.0	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.0	GO:0051940	regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.0	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	0.1	GO:0051923	sulfation(GO:0051923)
0.0	0.0	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.0	GO:0009137	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0	0.5	GO:0043330	response to exogenous dsRNA(GO:0043330)
0.0	0.0	GO:0009113	purine nucleobase biosynthetic process(GO:0009113)
0.0	0.0	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:0061157	mRNA destabilization(GO:0061157)
0.0	0.0	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.1	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.0	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.0	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.0	GO:0071223	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0	0.0	GO:0060051	negative regulation of protein glycosylation(GO:0060051)
0.0	0.0	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.0	0.2	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.1	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.0	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.2	0.6	GO:0097413	Lewy body(GO:0097413)
0.2	0.7	GO:0005726	perichromatin fibrils(GO:0005726)
0.2	0.6	GO:0044316	cone cell pedicle(GO:0044316)
0.1	0.7	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.5	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1	0.6	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1	0.3	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.1	0.3	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.1	0.2	GO:0000811	GINS complex(GO:0000811)
0.1	0.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.5	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1	0.2	GO:0097451	glial limiting end-foot(GO:0097451)
0.1	0.3	GO:0031094	platelet dense tubular network(GO:0031094)
0.1	0.4	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1	0.6	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.2	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.9	GO:0043034	costamere(GO:0043034)
0.0	0.4	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.2	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.4	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.2	GO:0045293	mRNA editing complex(GO:0045293)
0.0	0.2	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0	0.2	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.7	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.4	GO:0070852	cell body fiber(GO:0070852)
0.0	0.3	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.1	GO:0031298	replication fork protection complex(GO:0031298)
0.0	0.2	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.2	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:1990696	USH2 complex(GO:1990696)
0.0	0.1	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	0.2	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.2	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.2	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
0.0	0.1	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.0	0.1	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.2	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0000805	X chromosome(GO:0000805)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.1	GO:0033647	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0	0.4	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.3	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0016011	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.9	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.5	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	0.4	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.2	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.1	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.0	0.0	GO:1990075	periciliary membrane compartment(GO:1990075)
0.0	0.6	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.3	GO:0000145	exocyst(GO:0000145)
0.0	0.0	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0061617	MICOS complex(GO:0061617)
0.0	1.6	GO:0031227	intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.1	GO:0045180	basal cortex(GO:0045180)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.8	GO:0005811	lipid particle(GO:0005811)
0.0	0.3	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.4	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.1	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.0	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.0	0.0	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520)
0.0	0.5	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.1	GO:1990111	spermatoproteasome complex(GO:1990111)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.1	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.0	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.0	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.0	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.1	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533)
0.0	0.0	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.0	GO:0048408	epidermal growth factor binding(GO:0048408)
0.4	1.5	GO:0034056	estrogen response element binding(GO:0034056)
0.3	1.2	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.2	0.7	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2	0.6	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.2	0.6	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2	0.5	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	0.4	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	0.4	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1	0.4	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.3	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.1	0.4	GO:0038181	bile acid receptor activity(GO:0038181)
0.1	0.8	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.1	0.8	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1	0.4	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	0.7	GO:0097322	7SK snRNA binding(GO:0097322)
0.1	0.4	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.3	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.5	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.9	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1	0.3	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.1	0.3	GO:0008384	IkappaB kinase activity(GO:0008384)
0.1	0.3	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1	0.3	GO:0055100	adiponectin binding(GO:0055100)
0.1	0.4	GO:0070728	leucine binding(GO:0070728)
0.1	0.2	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1	0.3	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.1	0.6	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	0.3	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1	0.2	GO:0070538	oleic acid binding(GO:0070538)
0.1	0.5	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.2	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.2	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	0.2	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1	0.3	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.1	0.3	GO:0052630	CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.1	0.3	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.2	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.1	0.2	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.0	0.2	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.1	GO:2001069	glycogen binding(GO:2001069)
0.0	0.5	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.2	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.3	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.2	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.9	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.3	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.2	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.4	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.4	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.2	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.5	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.2	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.2	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.5	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.9	GO:0052713	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0	0.2	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.2	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.0	0.8	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.2	GO:1990405	protein antigen binding(GO:1990405)
0.0	0.4	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313)
0.0	0.2	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.4	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.2	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.2	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0031779	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.5	GO:0030552	cAMP binding(GO:0030552)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.2	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.0	GO:0030351	inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity(GO:0030351) inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity(GO:0030352) inositol pentakisphosphate phosphatase activity(GO:0052827)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.1	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.1	GO:0004556	alpha-amylase activity(GO:0004556)
0.0	0.3	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.3	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.1	GO:0070061	fructose binding(GO:0070061)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.0	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.4	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.2	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.2	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.2	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	1.1	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.4	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.0	0.1	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	0.1	GO:0032564	dATP binding(GO:0032564)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	1.3	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	0.2	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.2	GO:0048185	activin binding(GO:0048185)
0.0	0.0	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.1	GO:0004936	alpha-adrenergic receptor activity(GO:0004936)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.0	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0035514	DNA demethylase activity(GO:0035514)
0.0	0.1	GO:0001602	pancreatic polypeptide receptor activity(GO:0001602)
0.0	0.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0018571	2,3-dihydroxy DDT 1,2-dioxygenase activity(GO:0018542) phenanthrene dioxygenase activity(GO:0018555) 2,2',3-trihydroxybiphenyl dioxygenase activity(GO:0018556) 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity(GO:0018557) 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity(GO:0018558) 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity(GO:0018559) protocatechuate 3,4-dioxygenase type II activity(GO:0018560) 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity(GO:0018561) 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity(GO:0018562) 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity(GO:0018563) carbazole 1,9a-dioxygenase activity(GO:0018564) dihydroxydibenzothiophene dioxygenase activity(GO:0018565) 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity(GO:0018566) styrene dioxygenase activity(GO:0018567) 3,4-dihydroxyphenanthrene dioxygenase activity(GO:0018568) hydroquinone 1,2-dioxygenase activity(GO:0018569) p-cumate 2,3-dioxygenase activity(GO:0018570) 2,3-dihydroxy-p-cumate dioxygenase activity(GO:0018571) 3,5-dichlorocatechol 1,2-dioxygenase activity(GO:0018572) 2-aminophenol 1,6-dioxygenase activity(GO:0018573) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity(GO:0018574) chlorocatechol 1,2-dioxygenase activity(GO:0018575) catechol dioxygenase activity(GO:0019114) dihydroxyfluorene dioxygenase activity(GO:0019117) 5-aminosalicylate dioxygenase activity(GO:0034543) 3-hydroxy-2-naphthoate 2,3-dioxygenase activity(GO:0034803) benzo(a)pyrene 11,12-dioxygenase activity(GO:0034806) benzo(a)pyrene 4,5-dioxygenase activity(GO:0034808) 4,5-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034810) benzo(a)pyrene 9,10-dioxygenase activity(GO:0034811) 9,10-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034812) benzo(a)pyrene 7,8-dioxygenase activity(GO:0034813) 7,8-dihydroxy benzo(a)pyrene dioxygenase activity(GO:0034814) 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity(GO:0034827) 2-mercaptobenzothiazole dioxygenase activity(GO:0034834) pyridine-3,4-diol dioxygenase activity(GO:0034895) pyrene dioxygenase activity(GO:0034920) 4,5-dihydroxypyrene dioxygenase activity(GO:0034922) phenanthrene-4-carboxylate dioxygenase activity(GO:0034934) tetrachlorobenzene dioxygenase activity(GO:0034935) 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity(GO:0034936) 2,3-dihydroxydiphenyl ether dioxygenase activity(GO:0034955) diphenyl ether 1,2-dioxygenase activity(GO:0034956) arachidonate 8(S)-lipoxygenase activity(GO:0036403) 4-hydroxycatechol 1,2-dioxygenase activity(GO:0047074)
0.0	0.1	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.1	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.2	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.9	GO:0005080	protein kinase C binding(GO:0005080)
0.0	0.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.0	GO:0032557	pyrimidine ribonucleotide binding(GO:0032557)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.2	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.0	0.1	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.0	0.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.1	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.1	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.0	0.1	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.5	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0	0.1	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.0	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.0	0.0	GO:0008297	single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0	0.6	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.3	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.4	GO:0034594	phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.0	0.1	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.0	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.5	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.0	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.0	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.0	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.1	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.0	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.0	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
0.0	0.0	GO:0015154	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.3	GO:0001221	transcription cofactor binding(GO:0001221)
0.0	0.4	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0033142	progesterone receptor binding(GO:0033142)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.0	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.0	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0005123	death receptor binding(GO:0005123)
0.0	0.0	GO:0008808	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0	0.0	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.0	0.0	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.0	0.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.0	GO:0016531	copper chaperone activity(GO:0016531) superoxide dismutase copper chaperone activity(GO:0016532)
0.0	0.0	GO:0019770	IgG receptor activity(GO:0019770)
0.0	0.0	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.0	GO:0004470	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.0	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.0	0.2	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.1	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.2	GO:0004629	phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0	0.1	GO:0019841	retinol binding(GO:0019841)
0.0	0.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.0	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	1.2	PID IGF1 PATHWAY	IGF1 pathway
0.0	1.7	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.6	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.7	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	1.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.4	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.5	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.2	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.5	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.8	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.0	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.1	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.8	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.3	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.3	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.2	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.2	PID IL27 PATHWAY	IL27-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	0.9	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	0.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	0.5	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	0.9	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	0.9	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.1	0.6	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	0.7	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	0.6	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	0.5	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	0.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	0.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.5	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.7	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.1	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.1	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.6	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.6	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.7	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.3	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.3	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.7	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.4	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.0	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.1	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.0	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.3	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.6	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.4	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.1	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.3	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.0	REACTOME MEMBRANE TRAFFICKING	Genes involved in Membrane Trafficking
0.0	0.1	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.6	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.2	REACTOME FRS2 MEDIATED CASCADE	Genes involved in FRS2-mediated cascade
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.4	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.9	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.3	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.6	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.2	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.2	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.2	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.2	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.2	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.0	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.0	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.0	REACTOME SIGNALING BY FGFR IN DISEASE	Genes involved in Signaling by FGFR in disease
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.2	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.0	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.1	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.2	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.1	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity

Results for Mnx1_Lhx6_Lmx1a

Z-value: 1.38

Motif logo

Transcription factors associated with Mnx1_Lhx6_Lmx1a

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Mnx1_Lhx6_Lmx1a motif across conditions

Conditions sorted by the z-value of the Mnx1_Lhx6_Lmx1a motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Mnx1_Lhx6_Lmx1a

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: