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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Msx1_Lhx9_Barx1_Rax_Dlx6

Z-value: 0.05

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Transcription factors associated with Msx1_Lhx9_Barx1_Rax_Dlx6

Gene Symbol Gene ID Gene Info
ENSMUSG00000048450.10 Msx1
ENSMUSG00000019230.8 Lhx9
ENSMUSG00000021381.4 Barx1
ENSMUSG00000024518.3 Rax
ENSMUSG00000029754.7 Dlx6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

GenePromoterDistanceAssociation probabilityPearson corr. coef.P-valuePlot
Barx1chr13_48659009_4865916039140.2051270.443.8e-01Click!
Barx1chr13_48653912_4865407590050.1650570.374.7e-01Click!
Barx1chr13_48655742_4865590571750.172819-0.246.5e-01Click!
Lhx9chr1_138831356_13883167521440.2616490.834.1e-02Click!
Lhx9chr1_138826941_13882726065590.1686840.108.5e-01Click!
Lhx9chr1_138835461_13883562118820.2819970.049.4e-01Click!
Msx1chr5_37823370_3782352711340.5155570.661.6e-01Click!
Msx1chr5_37818319_3781850161720.2072350.621.9e-01Click!
Msx1chr5_37824534_37824701340.9786960.443.9e-01Click!
Msx1chr5_37849248_37849752249170.1688810.394.5e-01Click!
Msx1chr5_37848731_37849060243120.1702610.256.3e-01Click!

Activity of the Msx1_Lhx9_Barx1_Rax_Dlx6 motif across conditions

Conditions sorted by the z-value of the Msx1_Lhx9_Barx1_Rax_Dlx6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_59786230_59786381 0.01 Gm17059
predicted gene 17059
13949
0.14
chr8_122697244_122697412 0.01 Gm10612
predicted gene 10612
532
0.59
chr7_143068403_143068570 0.00 Tssc4
tumor-suppressing subchromosomal transferable fragment 4
763
0.46
chr4_33248900_33249090 0.00 Pnrc1
proline-rich nuclear receptor coactivator 1
485
0.78
chr1_165766009_165766175 0.00 Creg1
cellular repressor of E1A-stimulated genes 1
2346
0.15
chr6_94273521_94273693 0.00 Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
9418
0.24
chr1_23146038_23146850 0.00 Ppp1r14bl
protein phosphatase 1, regulatory inhibitor subunit 14B like
44191
0.14
chr2_115888561_115888772 0.00 Meis2
Meis homeobox 2
15704
0.28
chr13_114348449_114348600 0.00 Ndufs4
NADH:ubiquinone oxidoreductase core subunit S4
39525
0.14
chr5_137981657_137981816 0.00 Azgp1
alpha-2-glycoprotein 1, zinc
168
0.89
chr15_102999275_102999447 0.00 Hoxc6
homeobox C6
1104
0.28
chr2_153584454_153584637 0.00 Commd7
COMM domain containing 7
48186
0.1
chr15_10685820_10685975 0.00 Rai14
retinoic acid induced 14
27643
0.16
chr14_70530138_70530323 0.00 Lgi3
leucine-rich repeat LGI family, member 3
455
0.68
chr12_7987781_7988288 0.00 Apob
apolipoprotein B
10255
0.22
chr11_76908664_76908965 0.00 Tmigd1
transmembrane and immunoglobulin domain containing 1
4252
0.2
chr5_117089265_117089549 0.00 Suds3
suppressor of defective silencing 3 homolog (S. cerevisiae)
9404
0.15
chr8_70528786_70528992 0.00 Fkbp8
FK506 binding protein 8
73
0.91
chr15_25623849_25624065 0.00 Myo10
myosin X
1408
0.41
chr3_127005234_127005396 0.00 Gm25501
predicted gene, 25501
54
0.96
chr18_84858118_84858492 0.00 Gm16146
predicted gene 16146
1242
0.4
chr3_132835072_132835238 0.00 Gm9403
predicted gene 9403
7241
0.15
chr4_123652088_123652262 0.00 Macf1
microtubule-actin crosslinking factor 1
12577
0.13
chr6_120579907_120580085 0.00 Gm44124
predicted gene, 44124
180
0.92
chr19_55855694_55855845 0.00 Ppnr
per-pentamer repeat gene
14097
0.24
chr11_107337882_107338046 0.00 Gm11716
predicted gene 11716
86
0.79
chr11_120819707_120820136 0.00 Fasn
fatty acid synthase
3859
0.11
chr7_101896586_101896755 0.00 Anapc15
anaphase promoting complex C subunit 15
193
0.86
chr4_59292456_59292607 0.00 Susd1
sushi domain containing 1
23435
0.17
chr5_89416345_89416742 0.00 Gc
vitamin D binding protein
19085
0.24
chr17_27907441_27908078 0.00 Taf11
TATA-box binding protein associated factor 11
24
0.5
chr14_20245752_20245947 0.00 Gm2048
predicted gene 2048
15083
0.11

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Msx1_Lhx9_Barx1_Rax_Dlx6

PNG image of the network

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Gene Ontology Analysis