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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Msx3

Z-value: 1.66

Motif logo

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Transcription factors associated with Msx3

Gene Symbol Gene ID Gene Info
Msx3
ENSMUSG00000025469.9 msh homeobox 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_140049374_140049526Msx33610.740301-0.552.5e-01Click!
chr7_140058149_140058300Msx391350.087534-0.226.8e-01Click!
chr7_140063217_140063374Msx3142060.081201-0.128.2e-01Click!
chr7_140061314_140061474Msx3123050.0833910.078.9e-01Click!

Activity of the Msx3 motif across conditions

Conditions sorted by the z-value of the Msx3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr9_20730600_20730850 1.56 Olfm2
 olfactomedin 2
 2496
 0.23
chr11_83271635_83271942 1.52 Gm23444
 predicted gene, 23444
 290
 0.8
chr8_24445565_24445716 1.44 Gm44620
 predicted gene 44620
 1457
 0.34
chr11_109733399_109733703 1.22 Fam20a
 family with sequence similarity 20, member A
 11272
 0.17
chr18_7847563_7847725 1.17 Gm50027
 predicted gene, 50027
 2709
 0.23
chr6_35874026_35874908 1.10 Gm43442
 predicted gene 43442
 52244
 0.17
chr17_83938813_83938978 1.09 Gm23905
 predicted gene, 23905
 8693
 0.12
chr6_126033747_126033913 1.06 Ntf3
 neurotrophin 3
 131130
 0.05
chr18_8939044_8939213 1.00 Gm37148
 predicted gene, 37148
 10893
 0.24
chr10_108350464_108350766 0.95 Gm23105
 predicted gene, 23105
 13050
 0.19
chr19_44027305_44027461 0.95 Cyp2c23
 cytochrome P450, family 2, subfamily c, polypeptide 23
 1816
 0.28
chr13_106525577_106525787 0.94 Gm48216
 predicted gene, 48216
 6135
 0.23
chr10_52294294_52294477 0.92 Gm6627
 predicted gene 6627
 49272
 0.09
chr12_118887325_118887612 0.90 Abcb5
 ATP-binding cassette, sub-family B (MDR/TAP), member 5
 3291
 0.3
chr9_33001470_33001748 0.89 Gm27166
 predicted gene 27166
 30182
 0.17
chr13_101967419_101967852 0.87 Gm17832
 predicted gene, 17832
 47215
 0.17
chr5_43157097_43157384 0.84 Gm42552
 predicted gene 42552
 8913
 0.21
chr14_69628830_69628981 0.83 Gm27177
 predicted gene 27177
 11369
 0.11
chr4_132129267_132129447 0.80 Oprd1
 opioid receptor, delta 1
 15129
 0.1
chr17_5012388_5012845 0.79 Arid1b
 AT rich interactive domain 1B (SWI-like)
 16187
 0.23
chr15_38661347_38661720 0.79 Atp6v1c1
 ATPase, H+ transporting, lysosomal V1 subunit C1
 400
 0.79
chr2_22589828_22590052 0.78 Gm13340
 predicted gene 13340
 293
 0.68
chr5_110596813_110596964 0.77 Galnt9
 polypeptide N-acetylgalactosaminyltransferase 9
 6633
 0.15
chr11_111605518_111605669 0.76 Gm11676
 predicted gene 11676
 7713
 0.32
chr9_66414274_66414486 0.76 Gm28379
 predicted gene 28379
 6261
 0.21
chr18_64325483_64325793 0.75 St8sia3os
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3, opposite strand
 8068
 0.16
chr7_45264516_45264678 0.74 Slc6a16
 solute carrier family 6, member 16
 3553
 0.09
chr12_69759378_69759543 0.74 Mir681
 microRNA 681
 4484
 0.15
chr1_4859119_4859327 0.73 Tcea1
 transcription elongation factor A (SII) 1
 1185
 0.36
chr2_178711802_178711999 0.72 Cdh26
 cadherin-like 26
 251270
 0.02
chr11_108782497_108782676 0.71 Cep112
 centrosomal protein 112
 30381
 0.16
chr1_34439675_34439854 0.71 Imp4
 IMP4, U3 small nucleolar ribonucleoprotein
 87
 0.49
chr8_76913299_76913495 0.71 Nr3c2
 nuclear receptor subfamily 3, group C, member 2
 5125
 0.24
chr15_31279226_31279377 0.70 Gm49296
 predicted gene, 49296
 2788
 0.19
chrX_140387482_140387633 0.70 Frmpd3
 FERM and PDZ domain containing 3
 5586
 0.23
chr3_116409014_116409188 0.70 Cdc14a
 CDC14 cell division cycle 14A
 3613
 0.2
chr15_99865164_99865320 0.70 Lima1
 LIM domain and actin binding 1
 9429
 0.08
chr13_92533605_92533774 0.69 Zfyve16
 zinc finger, FYVE domain containing 16
 2821
 0.27
chr6_17255791_17255960 0.69 Cav2
 caveolin 2
 25310
 0.17
chr7_66740464_66740653 0.69 Gm10623
 predicted gene 10623
 2754
 0.19
chr4_142088876_142089143 0.68 Tmem51os1
 Tmem51 opposite strand 1
 4153
 0.16
chr3_28736802_28736989 0.67 1700112D23Rik
 RIKEN cDNA 1700112D23 gene
 5345
 0.16
chr15_77773367_77773546 0.66 Myh9
 myosin, heavy polypeptide 9, non-muscle
 3677
 0.15
chr15_82290409_82290560 0.66 Septin3
 septin 3
 6054
 0.09
chr13_58058115_58058280 0.65 Mir874
 microRNA 874
 34997
 0.13
chr5_105830536_105830687 0.65 Lrrc8d
 leucine rich repeat containing 8D
 6100
 0.14
chr8_81366726_81366902 0.64 Inpp4b
 inositol polyphosphate-4-phosphatase, type II
 24252
 0.21
chr3_58894660_58894811 0.64 Clrn1
 clarin 1
 9395
 0.2
chr19_27411429_27411595 0.64 Pum3
 pumilio RNA-binding family member 3
 752
 0.7
chr12_35294499_35294705 0.63 Gm44396
 predicted gene, 44396
 14289
 0.25
chr12_85818362_85818513 0.63 Erg28
 ergosterol biosynthesis 28
 3813
 0.2
chr9_90303778_90304052 0.63 Gm30849
 predicted gene, 30849
 115
 0.96
chr3_65357881_65358061 0.63 Kcnab1
 potassium voltage-gated channel, shaker-related subfamily, beta member 1
 4204
 0.18
chr2_69061493_69062160 0.62 Gm38377
 predicted gene, 38377
 43730
 0.11
chr11_87449212_87449363 0.62 Rnu3b3
 U3B small nuclear RNA 3
 660
 0.48
chr2_75202592_75202875 0.62 Gm13653
 predicted gene 13653
 10456
 0.15
chr2_169634592_169634925 0.61 Tshz2
 teashirt zinc finger family member 2
 1082
 0.55
chr5_90465676_90466047 0.61 Alb
 albumin
 3161
 0.2
chr14_61361356_61361514 0.61 Ebpl
 emopamil binding protein-like
 996
 0.42
chr4_97099326_97100044 0.60 Gm27521
 predicted gene, 27521
 182665
 0.03
chr1_174921018_174921617 0.60 Grem2
 gremlin 2, DAN family BMP antagonist
 502
 0.88
chr9_123530850_123531001 0.60 Sacm1l
 SAC1 suppressor of actin mutations 1-like (yeast)
 1043
 0.5
chr1_52597389_52597548 0.60 Gm5527
 predicted gene 5527
 12950
 0.13
chr12_73584095_73584268 0.60 Prkch
 protein kinase C, eta
 615
 0.73
chrX_100447058_100447240 0.59 Awat2
 acyl-CoA wax alcohol acyltransferase 2
 4432
 0.18
chr11_86361937_86362118 0.59 Med13
 mediator complex subunit 13
 4425
 0.24
chr18_37949922_37950073 0.58 Hdac3
 histone deacetylase 3
 4433
 0.1
chr11_100330372_100330542 0.56 Gast
 gastrin
 3950
 0.09
chr4_35148195_35148566 0.56 Ifnk
 interferon kappa
 3676
 0.22
chr1_65186286_65186491 0.56 Idh1
 isocitrate dehydrogenase 1 (NADP+), soluble
 50
 0.79
chr1_60862632_60862783 0.56 Gm38137
 predicted gene, 38137
 17631
 0.12
chr14_121469692_121469843 0.55 Gm33299
 predicted gene, 33299
 14005
 0.17
chr10_127355627_127355790 0.55 Inhbe
 inhibin beta-E
 1297
 0.23
chr17_55749906_55750061 0.55 Adgre4
 adhesion G protein-coupled receptor E4
 1
 0.97
chr2_132595408_132595654 0.54 AU019990
 expressed sequence AU019990
 2664
 0.22
chr12_26976640_26976824 0.54 Gm9866
 predicted gene 9866
 138263
 0.05
chr4_141718181_141718503 0.54 Ddi2
 DNA-damage inducible protein 2
 5077
 0.14
chr18_35681549_35681863 0.54 Dnajc18
 DnaJ heat shock protein family (Hsp40) member C18
 5037
 0.1
chr19_26754124_26754675 0.53 Smarca2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
 799
 0.69
chr9_61370295_61371248 0.53 Gm10655
 predicted gene 10655
 856
 0.53
chr5_114985285_114985436 0.52 1810017P11Rik
 RIKEN cDNA 1810017P11 gene
 9904
 0.09
chr12_106477969_106478140 0.52 Gm3191
 predicted gene 3191
 18904
 0.17
chr3_133765600_133766533 0.52 Gm6135
 prediticted gene 6135
 25438
 0.2
chr11_94370063_94370224 0.51 Abcc3
 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
 2220
 0.26
chr14_19839858_19840045 0.51 D14Ertd670e
 DNA segment, Chr 14, ERATO Doi 670, expressed
 1026
 0.48
chr19_23024753_23025259 0.51 Gm50136
 predicted gene, 50136
 36448
 0.17
chr3_85550361_85550689 0.51 Gm42812
 predicted gene 42812
 2864
 0.24
chr8_128687947_128688299 0.51 Itgb1
 integrin beta 1 (fibronectin receptor beta)
 2253
 0.29
chr7_145056434_145056606 0.50 Gm45181
 predicted gene 45181
 106476
 0.05
chr2_120170818_120170979 0.50 Ehd4
 EH-domain containing 4
 16292
 0.15
chr18_46336206_46336490 0.50 4930415P13Rik
 RIKEN cDNA 4930415P13 gene
 4081
 0.17
chr13_115595390_115595557 0.50 Gm6035
 predicted gene 6035
 65701
 0.14
chr11_70713419_70713657 0.49 Mir6925
 microRNA 6925
 7548
 0.08
chr1_185836743_185836921 0.49 Gm9722
 predicted gene 9722
 42053
 0.18
chr17_63343186_63343351 0.49 Gm17228
 predicted gene 17228
 4142
 0.22
chr8_93154464_93154622 0.48 Gm45910
 predicted gene 45910
 427
 0.78
chr14_45453135_45453314 0.48 Gm34250
 predicted gene, 34250
 6151
 0.13
chr1_73931861_73932066 0.48 Tns1
 tensin 1
 1152
 0.54
chr13_58999542_58999699 0.48 Gm34245
 predicted gene, 34245
 78676
 0.08
chr17_8343197_8343376 0.48 Prr18
 proline rich 18
 2547
 0.17
chr15_64334950_64335143 0.48 Gm10926
 predicted gene 10926
 6029
 0.2
chr18_20187452_20187603 0.48 Dsg1c
 desmoglein 1 gamma
 59813
 0.12
chr18_56607212_56607383 0.48 Gm50283
 predicted gene, 50283
 6362
 0.14
chr1_24042012_24042182 0.48 Fam135a
 family with sequence similarity 135, member A
 13011
 0.18
chr2_132134128_132134319 0.48 Gm14051
 predicted gene 14051
 10310
 0.16
chr13_14192509_14192814 0.47 Arid4b
 AT rich interactive domain 4B (RBP1-like)
 1484
 0.37
chr10_115337191_115337351 0.47 Tmem19
 transmembrane protein 19
 11793
 0.14
chr14_60635934_60636102 0.47 Spata13
 spermatogenesis associated 13
 1263
 0.52
chr3_149170339_149170514 0.47 Gm42647
 predicted gene 42647
 39845
 0.16
chr15_61562347_61562502 0.47 Gm49498
 predicted gene, 49498
 18241
 0.28
chr14_30351980_30352170 0.47 Cacna1d
 calcium channel, voltage-dependent, L type, alpha 1D subunit
 889
 0.57
chr2_131180305_131180466 0.47 Cenpb
 centromere protein B
 318
 0.78
chr6_4009646_4009797 0.47 Gng11
 guanine nucleotide binding protein (G protein), gamma 11
 5817
 0.17
chr4_149453846_149453997 0.47 Rbp7
 retinol binding protein 7, cellular
 497
 0.65
chr9_55233053_55233204 0.46 Nrg4
 neuregulin 4
 9333
 0.17
chr7_46767478_46767782 0.46 Hps5
 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
 833
 0.4
chr3_41465297_41465458 0.46 Gm40040
 predicted gene, 40040
 16508
 0.13
chr9_8003099_8003325 0.46 Yap1
 yes-associated protein 1
 545
 0.68
chr9_119341051_119341435 0.46 Acaa1a
 acetyl-Coenzyme A acyltransferase 1A
 51
 0.65
chr7_84112155_84112947 0.45 Cemip
 cell migration inducing protein, hyaluronan binding
 26049
 0.14
chr18_10251145_10251313 0.44 Gm5686
 predicted gene 5686
 10978
 0.14
chr10_53753298_53753451 0.44 Fam184a
 family with sequence similarity 184, member A
 2251
 0.35
chr16_70563529_70563695 0.44 Gbe1
 glucan (1,4-alpha-), branching enzyme 1
 2618
 0.36
chr11_34998043_34998214 0.44 Gm25799
 predicted gene, 25799
 99111
 0.07
chr2_82446048_82446229 0.44 A130030D18Rik
 RIKEN cDNA A130030D18 gene
 53936
 0.14
chr13_16269739_16270144 0.43 Gm48491
 predicted gene, 48491
 7897
 0.23
chr6_31148929_31149080 0.43 Gm37728
 predicted gene, 37728
 1585
 0.28
chr2_48816834_48817005 0.43 Acvr2a
 activin receptor IIA
 2810
 0.3
chr19_43511120_43511314 0.43 Got1
 glutamic-oxaloacetic transaminase 1, soluble
 4648
 0.14
chr16_27391982_27392165 0.43 Ccdc50
 coiled-coil domain containing 50
 2105
 0.33
chr16_26248335_26248499 0.42 Cldn1
 claudin 1
 112377
 0.07
chr17_36032663_36032990 0.42 H2-T23
 histocompatibility 2, T region locus 23
 29
 0.92
chr2_132143179_132143352 0.42 Gm14051
 predicted gene 14051
 1268
 0.37
chr10_68248229_68248529 0.42 Arid5b
 AT rich interactive domain 5B (MRF1-like)
 30342
 0.19
chr3_118507933_118508602 0.42 Gm37773
 predicted gene, 37773
 17884
 0.14
chr10_9902050_9902213 0.42 Gm46210
 predicted gene, 46210
 818
 0.46
chr13_78124273_78124441 0.42 Gm18990
 predicted gene, 18990
 3287
 0.19
chr10_41627379_41627538 0.41 Ccdc162
 coiled-coil domain containing 162
 14621
 0.15
chr15_34493251_34493646 0.41 Rida
 reactive intermediate imine deaminase A homolog
 1723
 0.21
chr9_122814663_122814835 0.41 Tcaim
 T cell activation inhibitor, mitochondrial
 9146
 0.12
chr3_138231897_138232387 0.41 Adh7
 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
 4091
 0.14
chr16_25351479_25351642 0.41 Tprg
 transformation related protein 63 regulated
 64739
 0.14
chr3_116967199_116967673 0.41 4930455H04Rik
 RIKEN cDNA 4930455H04 gene
 831
 0.45
chr10_70924491_70924642 0.41 Bicc1
 BicC family RNA binding protein 1
 23923
 0.12
chr5_34380236_34380602 0.41 Fam193a
 family with sequence homology 193, member A
 10486
 0.14
chr2_77563772_77563946 0.41 Zfp385b
 zinc finger protein 385B
 1879
 0.47
chr2_122081842_122082023 0.40 Spg11
 SPG11, spatacsin vesicle trafficking associated
 36364
 0.11
chr12_3811591_3811763 0.40 Dnmt3a
 DNA methyltransferase 3A
 4517
 0.2
chr19_43767883_43768034 0.40 Cutc
 cutC copper transporter
 3085
 0.18
chr7_123124873_123125354 0.40 Tnrc6a
 trinucleotide repeat containing 6a
 857
 0.66
chr17_26024045_26024196 0.40 Rab11fip3
 RAB11 family interacting protein 3 (class II)
 2260
 0.16
chr1_72145974_72146125 0.39 Gm4319
 predicted gene 4319
 24048
 0.15
chr11_16883025_16883203 0.39 Egfr
 epidermal growth factor receptor
 4964
 0.23
chr9_64457749_64457913 0.39 Megf11
 multiple EGF-like-domains 11
 43505
 0.16
chr19_12005901_12006348 0.39 Olfr1421-ps1
 olfactory receptor 1421, pseudogene 1
 14051
 0.08
chr3_94338287_94338715 0.39 Gm43743
 predicted gene 43743
 3169
 0.1
chr6_71823720_71824038 0.38 Mrpl35
 mitochondrial ribosomal protein L35
 69
 0.95
chr3_61217316_61217479 0.38 Gm37719
 predicted gene, 37719
 74049
 0.1
chr19_36735506_36735662 0.38 Ppp1r3c
 protein phosphatase 1, regulatory subunit 3C
 1069
 0.56
chr2_63580816_63581021 0.38 Gm23503
 predicted gene, 23503
 148724
 0.05
chr4_105215829_105216004 0.38 Plpp3
 phospholipid phosphatase 3
 58569
 0.15
chr7_111726929_111727297 0.38 Galnt18
 polypeptide N-acetylgalactosaminyltransferase 18
 52864
 0.15
chr12_35294940_35295100 0.38 Gm44396
 predicted gene, 44396
 13871
 0.25
chr17_84385788_84385950 0.38 Gm24722
 predicted gene, 24722
 5560
 0.22
chr1_136229022_136229181 0.37 Inava
 innate immunity activator
 918
 0.4
chr1_133251724_133252043 0.37 Gm19461
 predicted gene, 19461
 2409
 0.23
chr11_83703751_83703986 0.37 Wfdc17
 WAP four-disulfide core domain 17
 123
 0.9
chr1_43066043_43066369 0.37 Tgfbrap1
 transforming growth factor, beta receptor associated protein 1
 5273
 0.14
chr4_65532386_65532616 0.37 Trim32
 tripartite motif-containing 32
 72485
 0.14
chr6_41044443_41044618 0.37 2210010C04Rik
 RIKEN cDNA 2210010C04 gene
 9021
 0.07
chr11_102040134_102040466 0.37 Cd300lg
 CD300 molecule like family member G
 1209
 0.28
chr17_8974900_8975051 0.37 1700010I14Rik
 RIKEN cDNA 1700010I14 gene
 13358
 0.23
chr12_57514709_57514889 0.37 Gm2568
 predicted gene 2568
 5825
 0.17
chr2_142767278_142767429 0.37 Gm22310
 predicted gene, 22310
 19543
 0.24
chr3_145621208_145621546 0.37 Znhit6
 zinc finger, HIT type 6
 25509
 0.15
chr11_7153168_7153348 0.37 Adcy1
 adenylate cyclase 1
 6624
 0.21
chr4_11865116_11865283 0.36 Gm25002
 predicted gene, 25002
 83688
 0.07
chr7_49397440_49397604 0.36 Nav2
 neuron navigator 2
 32801
 0.18
chr9_79213455_79213848 0.36 Gm47499
 predicted gene, 47499
 11644
 0.17
chrX_74270256_74270420 0.36 Rpl10
 ribosomal protein L10
 474
 0.52
chr4_116689870_116690150 0.36 Prdx1
 peroxiredoxin 1
 2698
 0.15
chr9_77662986_77663137 0.36 Klhl31
 kelch-like 31
 26561
 0.14
chr11_29719333_29719653 0.36 Rtn4
 reticulon 4
 930
 0.53
chr10_108074024_108074345 0.36 Gm47999
 predicted gene, 47999
 68248
 0.12
chr15_97031052_97031203 0.36 Slc38a4
 solute carrier family 38, member 4
 84
 0.98
chr15_10273020_10273171 0.36 Prlr
 prolactin receptor
 23535
 0.21
chr11_60537500_60537667 0.36 Alkbh5
 alkB homolog 5, RNA demethylase
 395
 0.72
chr12_14302401_14302552 0.36 Gm16497
 predicted gene 16497
 40920
 0.19
chr15_77208076_77208227 0.36 Rbfox2
 RNA binding protein, fox-1 homolog (C. elegans) 2
 4715
 0.18
chr3_138426007_138426180 0.36 Adh4
 alcohol dehydrogenase 4 (class II), pi polypeptide
 10598
 0.13
chr5_9056138_9056296 0.36 Gm40264
 predicted gene, 40264
 21093
 0.14
chr6_50176334_50176508 0.36 Mpp6
 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
 3879
 0.27
chr15_61398964_61399115 0.36 Gm24696
 predicted gene, 24696
 41035
 0.19
chr6_121963215_121963471 0.36 Mug2
 murinoglobulin 2
 43418
 0.12
chr8_115984246_115984444 0.35 Gm45733
 predicted gene 45733
 12274
 0.31
chr14_64331778_64331949 0.35 Msra
 methionine sulfoxide reductase A
 85085
 0.09
chr1_24612181_24612351 0.35 Gm28439
 predicted gene 28439
 144
 0.72
chr6_94814990_94815159 0.35 Gm7833
 predicted gene 7833
 5456
 0.15
chr8_123032866_123033108 0.35 Ankrd11
 ankyrin repeat domain 11
 9033
 0.11
chr4_8361870_8362071 0.35 Gm37386
 predicted gene, 37386
 92277
 0.08

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Msx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 0.4 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1 0.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.4 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.1 0.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.5 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.1 0.1 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.3 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.2 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 0.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.2 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.2 GO:0043134 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.1 0.3 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.1 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.1 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.1 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.2 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.1 0.3 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.2 GO:0072566 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0 0.0 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:0035811 negative regulation of urine volume(GO:0035811)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.3 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.0 0.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.6 GO:0035278 miRNA mediated inhibition of translation(GO:0035278)
0.0 0.3 GO:0002591 positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591)
0.0 0.1 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0 0.1 GO:2000173 negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.4 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.2 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.1 GO:0097503 sialylation(GO:0097503)
0.0 0.1 GO:0001907 killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0 0.1 GO:0003213 cardiac right atrium morphogenesis(GO:0003213)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0007403 glial cell fate determination(GO:0007403)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.1 GO:0071926 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0 0.1 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0034627 'de novo' NAD biosynthetic process(GO:0034627)
0.0 0.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 0.1 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.1 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0 0.4 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.2 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.0 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.3 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838)
0.0 0.0 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
0.0 0.1 GO:0046499 S-adenosylmethioninamine metabolic process(GO:0046499)
0.0 0.1 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0090230 regulation of centromere complex assembly(GO:0090230)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.1 GO:0061144 alveolar secondary septum development(GO:0061144)
0.0 0.0 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.4 GO:0044783 G1 DNA damage checkpoint(GO:0044783)
0.0 0.1 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.2 GO:0046040 IMP metabolic process(GO:0046040)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.3 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.0 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0 0.1 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.1 GO:0015817 histidine transport(GO:0015817)
0.0 0.1 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.0 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.0 0.1 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.0 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.0 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.0 GO:0061643 chemorepulsion of axon(GO:0061643)
0.0 0.0 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.0 0.0 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.0 GO:0040033 negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.0 GO:0042504 tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519)
0.0 0.0 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.0 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0010663 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.0 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.0 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.0 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.0 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 0.0 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.0 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.0 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.1 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.0 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0099515 actin filament-based transport(GO:0099515)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0071404 cellular response to low-density lipoprotein particle stimulus(GO:0071404)
0.0 0.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.0 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:1990168 protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0 0.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.0 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077)
0.0 0.1 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.0 0.0 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.0 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.0 0.0 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.0 GO:0001997 positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.0 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.1 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.1 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.4 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.4 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.0 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.0 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.0 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.3 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.0 GO:1903525 regulation of membrane tubulation(GO:1903525)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.0 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.0 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.0 0.3 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.0 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.0 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.0 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.0 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.0 GO:1903116 positive regulation of actin filament-based movement(GO:1903116)
0.0 0.0 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.2 GO:0033269 internode region of axon(GO:0033269)
0.1 0.2 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.1 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.3 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.4 GO:0031941 filamentous actin(GO:0031941)
0.0 0.0 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.0 GO:0071203 WASH complex(GO:0071203)
0.0 0.0 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.0 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.3 GO:0030519 snoRNP binding(GO:0030519)
0.1 0.4 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 0.3 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.4 GO:0003696 satellite DNA binding(GO:0003696)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.5 GO:0036122 BMP binding(GO:0036122)
0.1 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.2 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.0 0.2 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.2 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.0 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0 0.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:1901474 L-histidine transmembrane transporter activity(GO:0005290) azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.0 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.3 GO:0019825 oxygen binding(GO:0019825)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.0 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.0 GO:0052827 inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity(GO:0030351) inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity(GO:0030352) inositol pentakisphosphate phosphatase activity(GO:0052827)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.8 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.0 REACTOME SIGNALLING BY NGF Genes involved in Signalling by NGF
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling