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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Neurod2_Bhlha15_Bhlhe22_Olig1

Z-value: 1.58

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Transcription factors associated with Neurod2_Bhlha15_Bhlhe22_Olig1

Gene Symbol	Gene ID	Gene Info
Neurod2 Ensembl NCBI MGI UniProt	ENSMUSG00000038255.6	neurogenic differentiation 2
Bhlha15 Ensembl NCBI MGI UniProt	ENSMUSG00000052271.7	basic helix-loop-helix family, member a15
Bhlhe22 Ensembl NCBI MGI UniProt	ENSMUSG00000025128.6	basic helix-loop-helix family, member e22
Olig1 Ensembl NCBI MGI UniProt	ENSMUSG00000046160.5	oligodendrocyte transcription factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr5_144189963_144190114	Bhlha15	248	0.891254	0.80	5.8e-02	Click!
chr5_144154672_144154827	Bhlha15	35537	0.100296	0.63	1.8e-01	Click!
chr5_144190161_144190333	Bhlha15	39	0.965803	0.51	3.0e-01	Click!
chr5_144190434_144190585	Bhlha15	223	0.904533	-0.38	4.6e-01	Click!
chr5_144158770_144158928	Bhlha15	31437	0.107537	0.03	9.5e-01	Click!
chr3_18051799_18052012	Bhlhe22	2269	0.304085	-0.81	5.0e-02	Click!
chr3_18051607_18051776	Bhlhe22	2483	0.287481	-0.78	6.5e-02	Click!
chr3_18052084_18052235	Bhlhe22	2015	0.329400	0.75	8.5e-02	Click!
chr3_18049898_18050087	Bhlhe22	4182	0.226329	0.73	1.0e-01	Click!
chr3_18049697_18049855	Bhlhe22	4398	0.222763	0.67	1.5e-01	Click!
chr11_98314182_98314345	Neurod2	15385	0.087744	0.62	1.9e-01	Click!
chr11_98338773_98338928	Neurod2	9202	0.087901	0.01	9.8e-01	Click!
chr16_91271040_91271639	Olig1	1567	0.281306	0.58	2.2e-01	Click!
chr16_91269537_91269705	Olig1	151	0.932505	-0.52	2.9e-01	Click!
chr16_91271709_91272039	Olig1	2102	0.219028	-0.50	3.1e-01	Click!
chr16_91270541_91270908	Olig1	952	0.447466	0.24	6.5e-01	Click!
chr16_91277504_91277668	Olig1	7814	0.129603	-0.22	6.7e-01	Click!

Activity of the Neurod2_Bhlha15_Bhlhe22_Olig1 motif across conditions

Conditions sorted by the z-value of the Neurod2_Bhlha15_Bhlhe22_Olig1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_112192603_112192792	2.54	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	33159	0.18
chr16_77467204_77467401	2.53	Gm37063	predicted gene, 37063	9632	0.12
chr7_13005790_13006506	2.33	Zbtb45	zinc finger and BTB domain containing 45	3652	0.09
chr2_126424829_126424981	2.15	Atp8b4	ATPase, class I, type 8B, member 4	66648	0.12
chr3_105773852_105774003	2.12	Gm43329	predicted gene 43329	3730	0.13
chr6_17477757_17477945	1.90	Met	met proto-oncogene	13390	0.21
chr7_118127356_118127544	1.87	Arl6ip1	ADP-ribosylation factor-like 6 interacting protein 1	1660	0.32
chr15_3465269_3465491	1.82	Ghr	growth hormone receptor	6264	0.31
chr16_43237255_43237440	1.71	Zbtb20	zinc finger and BTB domain containing 20	1308	0.49
chr10_24835038_24835256	1.71	Enpp3	ectonucleotide pyrophosphatase/phosphodiesterase 3	966	0.55
chr9_89704113_89704278	1.70	Tmed3	transmembrane p24 trafficking protein 3	628	0.68
chr11_105235813_105236112	1.69	Tlk2	tousled-like kinase 2 (Arabidopsis)	10796	0.19
chr5_134427782_134427997	1.66	n-R5s178	nuclear encoded rRNA 5S 178	11650	0.11
chr2_178676885_178677036	1.64	Cdh26	cadherin-like 26	216330	0.02
chr1_67167545_67167748	1.57	Cps1	carbamoyl-phosphate synthetase 1	44620	0.15
chr10_71177574_71177846	1.52	1700113B09Rik	RIKEN cDNA 1700113B09 gene	3326	0.15
chr1_58653433_58653690	1.51	Gm20257	predicted gene, 20257	920	0.43
chr15_76091943_76092118	1.50	Nrbp2	nuclear receptor binding protein 2	403	0.65
chr4_48133092_48133331	1.48	Stx17	syntaxin 17	8276	0.23
chr11_120280886_120281046	1.47	Gm47297	predicted gene, 47297	6479	0.11
chr17_28513542_28513712	1.46	Fkbp5	FK506 binding protein 5	2270	0.13
chr4_154222608_154222801	1.46	Gm13132	predicted gene 13132	2163	0.25
chr1_13587485_13587657	1.44	Tram1	translocating chain-associating membrane protein 1	2304	0.32
chr10_87896571_87896873	1.43	Igf1os	insulin-like growth factor 1, opposite strand	33341	0.15
chr5_145855582_145856014	1.43	Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	20893	0.14
chr8_47707326_47707477	1.43	E030037K01Rik	RIKEN cDNA E030037K01 gene	5865	0.11
chr15_10637284_10637520	1.42	Gm10389	predicted gene 10389	37065	0.13
chr10_75502043_75502210	1.37	Gm48148	predicted gene, 48148	6065	0.12
chr13_49581593_49581758	1.36	Omd	osteomodulin	787	0.57
chr2_43592382_43592533	1.31	Kynu	kynureninase	7158	0.3
chr13_18759751_18760140	1.31	Vps41	VPS41 HOPS complex subunit	19898	0.25
chr13_95862241_95862392	1.27	Iqgap2	IQ motif containing GTPase activating protein 2	29441	0.17
chr16_32670450_32670601	1.27	Tnk2	tyrosine kinase, non-receptor, 2	1132	0.39
chr6_135011218_135011382	1.27	Ddx47	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47	312	0.87
chr7_90045659_90045810	1.26	Gm44861	predicted gene 44861	3037	0.18
chr14_70332418_70332599	1.24	Slc39a14	solute carrier family 39 (zinc transporter), member 14	990	0.42
chr2_122206384_122206535	1.24	Gm14050	predicted gene 14050	1461	0.25
chr2_160865219_160865594	1.23	Zhx3	zinc fingers and homeoboxes 3	5775	0.14
chr10_89747270_89747592	1.21	Uhrf1bp1l	UHRF1 (ICBP90) binding protein 1-like	2193	0.3
chr3_18461158_18461350	1.21	Gm30667	predicted gene, 30667	0	0.98
chr9_104036465_104036618	1.20	Nphp3	nephronophthisis 3 (adolescent)	693	0.51
chr11_20136381_20136565	1.18	Gm12030	predicted gene 12030	6095	0.17
chr10_54034976_54035145	1.18	Gm47917	predicted gene, 47917	28751	0.17
chr11_7148395_7148569	1.18	Adcy1	adenylate cyclase 1	11400	0.2
chr3_36532798_36533054	1.16	Gm11549	predicted gene 11549	542	0.65
chr5_124228161_124228330	1.15	Pitpnm2os1	phosphatidylinositol transfer protein, membrane-associated 2, opposite strand 1	1480	0.26
chr1_98733707_98733870	1.15	Gm29460	predicted gene 29460	31053	0.24
chr2_18071958_18072154	1.15	Mllt10	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10	7215	0.12
chr18_46603564_46603715	1.13	Eif1a	eukaryotic translation initiation factor 1A	5625	0.15
chr9_94053316_94053467	1.12	Gm5369	predicted gene 5369	86071	0.11
chr17_83841749_83842226	1.09	Haao	3-hydroxyanthranilate 3,4-dioxygenase	4762	0.19
chr4_109867603_109867790	1.09	Faf1	Fas-associated factor 1	26911	0.21
chr15_103274624_103274786	1.09	Copz1	coatomer protein complex, subunit zeta 1	1793	0.2
chr1_130679036_130679484	1.08	C4bp-ps1	complement component 4 binding protein, pseudogene 1	4811	0.12
chr10_20165191_20165424	1.08	Map7	microtubule-associated protein 7	5473	0.19
chr4_105100779_105100973	1.08	Prkaa2	protein kinase, AMP-activated, alpha 2 catalytic subunit	9014	0.27
chr6_94669947_94670290	1.07	Lrig1	leucine-rich repeats and immunoglobulin-like domains 1	8747	0.23
chr14_57936391_57936569	1.07	Micu2	mitochondrial calcium uptake 2	16548	0.17
chr14_117447795_117448102	1.07	Mir6239	microRNA 6239	505899	0.0
chr2_110302325_110302952	1.06	Bbox1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)	3103	0.29
chr13_9106316_9106467	1.06	Larp4b	La ribonucleoprotein domain family, member 4B	12409	0.15
chr13_23861435_23861629	1.05	Slc17a1	solute carrier family 17 (sodium phosphate), member 1	6218	0.1
chr8_122984437_122984588	1.05	Gm24445	predicted gene, 24445	1569	0.3
chr8_45731419_45731570	1.05	Sorbs2	sorbin and SH3 domain containing 2	11687	0.2
chr4_143186426_143186604	1.01	Prdm2	PR domain containing 2, with ZNF domain	8220	0.14
chr1_43942899_43943057	1.01	Tpp2	tripeptidyl peptidase II	8933	0.14
chr5_71830651_71830802	1.01	Gabrb1	gamma-aminobutyric acid (GABA) A receptor, subunit beta 1	130794	0.05
chr13_75730593_75731025	1.00	Gm48302	predicted gene, 48302	3530	0.17
chr9_115401508_115401659	1.00	Gm9487	predicted gene 9487	3566	0.16
chr8_42311184_42311349	1.00	Gm6180	predicted pseudogene 6180	64355	0.15
chr7_13046054_13046374	0.99	Mzf1	myeloid zinc finger 1	6166	0.08
chr7_134169898_134170246	0.99	Adam12	a disintegrin and metallopeptidase domain 12 (meltrin alpha)	2872	0.33
chr7_114362001_114362175	0.98	4933406I18Rik	RIKEN cDNA 4933406I18 gene	52933	0.12
chr7_115858582_115858733	0.97	Sox6	SRY (sex determining region Y)-box 6	1195	0.62
chr5_49328925_49329076	0.96	Kcnip4	Kv channel interacting protein 4	43341	0.13
chr13_93654093_93654261	0.96	Bhmt	betaine-homocysteine methyltransferase	16216	0.13
chr9_95578142_95578303	0.96	Paqr9	progestin and adipoQ receptor family member IX	18565	0.12
chr12_75472201_75472538	0.96	Gm47690	predicted gene, 47690	36376	0.16
chr11_32225384_32225575	0.96	Mpg	N-methylpurine-DNA glycosylase	1026	0.36
chr11_32689574_32689725	0.96	Fbxw11	F-box and WD-40 domain protein 11	46745	0.14
chr10_119231276_119231451	0.95	Cand1	cullin associated and neddylation disassociated 1	7940	0.21
chr12_100520010_100520216	0.95	Ttc7b	tetratricopeptide repeat domain 7B	578	0.73
chr18_3830693_3830853	0.94	Rpl7a-ps6	ribosomal protein L7A, pseudogene 6	27807	0.21
chr5_143676708_143676859	0.93	Cyth3	cytohesin 3	25542	0.15
chr6_59988893_59989044	0.92	Gm5570	predicted gene 5570	42999	0.16
chr8_124257183_124257380	0.91	Galnt2	polypeptide N-acetylgalactosaminyltransferase 2	25773	0.15
chr11_78204838_78204989	0.91	Proca1	protein interacting with cyclin A1	10167	0.06
chr2_132694471_132694624	0.90	Shld1	shieldin complex subunit 1	3572	0.14
chr7_80971648_80971827	0.90	Gm18782	predicted gene, 18782	8156	0.11
chr12_71049910_71050272	0.89	Arid4a	AT rich interactive domain 4A (RBP1-like)	1750	0.33
chr9_79730657_79730882	0.88	Col12a1	collagen, type XII, alpha 1	11938	0.16
chr2_48981052_48981464	0.88	Orc4	origin recognition complex, subunit 4	30981	0.18
chr13_67830741_67831099	0.88	4930525G20Rik	RIKEN cDNA 4930525G20 gene	65	0.66
chr12_78245635_78245786	0.87	Gm18899	predicted gene, 18899	10725	0.14
chr7_98380899_98381253	0.87	Tsku	tsukushi, small leucine rich proteoglycan	19748	0.14
chr10_87904063_87904214	0.87	Igf1os	insulin-like growth factor 1, opposite strand	40757	0.13
chr2_34903026_34903177	0.86	Phf19	PHD finger protein 19	1051	0.36
chr1_93476240_93476477	0.85	Hdlbp	high density lipoprotein (HDL) binding protein	2019	0.22
chr2_179261314_179261512	0.85	Gm14293	predicted gene 14293	20923	0.24
chr4_150703102_150703286	0.85	Gm16079	predicted gene 16079	24402	0.18
chr8_105051388_105051952	0.85	Gm45724	predicted gene 45724	202	0.87
chr5_140113147_140113315	0.84	Mad1l1	MAD1 mitotic arrest deficient 1-like 1	2235	0.25
chr4_126764112_126764263	0.84	AU040320	expressed sequence AU040320	10361	0.13
chr6_72898393_72898822	0.84	Kcmf1	potassium channel modulatory factor 1	476	0.76
chr5_86903628_86904406	0.84	Ugt2b34	UDP glucuronosyltransferase 2 family, polypeptide B34	2920	0.15
chr3_144285992_144286165	0.84	Gm43446	predicted gene 43446	2267	0.32
chr8_117674685_117674877	0.84	Sdr42e1	short chain dehydrogenase/reductase family 42E, member 1	1092	0.39
chr9_48760428_48760825	0.83	Zbtb16	zinc finger and BTB domain containing 16	75319	0.1
chr9_14215776_14216011	0.83	Gm47564	predicted gene, 47564	11810	0.17
chr14_21088324_21088564	0.83	Adk	adenosine kinase	12292	0.21
chr11_97822613_97823289	0.82	Lasp1	LIM and SH3 protein 1	7703	0.09
chr9_70421753_70421981	0.82	Ccnb2	cyclin B2	320	0.87
chr4_84637543_84637754	0.81	Bnc2	basonuclin 2	37348	0.19
chr3_135468547_135468720	0.81	Ube2d3	ubiquitin-conjugating enzyme E2D 3	6175	0.11
chr2_71498544_71498972	0.80	Gm23253	predicted gene, 23253	3487	0.17
chr7_27048742_27048893	0.80	Gm50480	predicted gene, 50480	221	0.87
chr12_104076433_104076597	0.80	Serpina4-ps1	serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1	4134	0.12
chr5_125332469_125332873	0.80	Scarb1	scavenger receptor class B, member 1	4952	0.15
chr13_93922310_93922490	0.79	Gm25534	predicted gene, 25534	911	0.6
chr3_121852936_121853213	0.79	Gm42593	predicted gene 42593	9768	0.15
chrX_106011307_106011645	0.79	Magt1	magnesium transporter 1	304	0.88
chrX_168795419_168795570	0.79	Arhgap6	Rho GTPase activating protein 6	395	0.89
chr12_98734159_98734532	0.79	Ptpn21	protein tyrosine phosphatase, non-receptor type 21	300	0.85
chr15_58982379_58982687	0.78	4930544F09Rik	RIKEN cDNA 4930544F09 gene	1603	0.34
chr7_143077201_143077361	0.78	Trpm5	transient receptor potential cation channel, subfamily M, member 5	2428	0.17
chr19_5568591_5568830	0.78	Ap5b1	adaptor-related protein complex 5, beta 1 subunit	636	0.46
chr16_43552061_43552212	0.78	Zbtb20	zinc finger and BTB domain containing 20	41828	0.16
chr3_149643434_149643585	0.77	Gm31121	predicted gene, 31121	16887	0.29
chr11_106267873_106268160	0.77	Smarcd2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2	217	0.85
chr3_96564338_96564527	0.77	Gm15441	predicted gene 15441	2369	0.11
chr1_67192197_67192413	0.76	Gm15668	predicted gene 15668	56895	0.12
chr9_74964831_74965084	0.76	Fam214a	family with sequence similarity 214, member A	11154	0.2
chr4_6452906_6453286	0.76	Nsmaf	neutral sphingomyelinase (N-SMase) activation associated factor	483	0.83
chr1_191153205_191153369	0.75	Fam71a	family with sequence similarity 71, member A	11530	0.12
chr4_19634612_19634775	0.75	Gm12353	predicted gene 12353	29242	0.16
chr5_87127647_87127925	0.75	Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	12532	0.11
chr13_58213548_58213699	0.74	Ubqln1	ubiquilin 1	1996	0.19
chr2_121450176_121450594	0.74	Gm22953	predicted gene, 22953	385	0.59
chr16_23518092_23518474	0.74	Gm45338	predicted gene 45338	1927	0.21
chr2_156153048_156153199	0.73	Romo1	reactive oxygen species modulator 1	8883	0.1
chr15_59066617_59066768	0.73	Mtss1	MTSS I-BAR domain containing 1	11228	0.23
chr12_86024555_86024706	0.73	Gm37804	predicted gene, 37804	44543	0.1
chr15_76574810_76574994	0.72	Adck5	aarF domain containing kinase 5	1456	0.18
chr7_30320817_30320974	0.72	E130208F15Rik	RIKEN cDNA E130208F15 gene	845	0.3
chr2_127586881_127587044	0.72	Zfp661	zinc finger protein 661	132	0.67
chr4_144896845_144896996	0.72	Dhrs3	dehydrogenase/reductase (SDR family) member 3	3701	0.26
chr15_50360598_50361185	0.72	Gm49198	predicted gene, 49198	73993	0.13
chr6_8032057_8032219	0.71	Col28a1	collagen, type XXVIII, alpha 1	9372	0.23
chr18_46718542_46718894	0.71	Cdo1	cysteine dioxygenase 1, cytosolic	9311	0.13
chr4_133554483_133554637	0.71	Nr0b2	nuclear receptor subfamily 0, group B, member 2	1184	0.29
chr17_55904335_55904551	0.70	Rpl21-ps6	ribosomal protein L21, pseudogene 6	11427	0.1
chr3_106496243_106496679	0.70	Dennd2d	DENN/MADD domain containing 2D	3286	0.17
chr15_58946705_58946856	0.70	Mtss1	MTSS I-BAR domain containing 1	6800	0.14
chr10_29362116_29362818	0.69	Rnf146	ring finger protein 146	25	0.81
chr4_19970512_19970663	0.69	4930480G23Rik	RIKEN cDNA 4930480G23 gene	27649	0.17
chr6_35873017_35873173	0.69	Gm43442	predicted gene 43442	53616	0.16
chr10_20331124_20331275	0.69	Bclaf1	BCL2-associated transcription factor 1	2055	0.21
chr8_126498607_126498804	0.68	Gm6091	predicted pseudogene 6091	22293	0.18
chr13_75226827_75226978	0.67	Gm19095	predicted gene, 19095	27688	0.23
chr10_56107193_56107362	0.67	Msl3l2	MSL3 like 2	360	0.89
chr5_66031695_66031902	0.67	Rbm47	RNA binding motif protein 47	22754	0.1
chr5_88929027_88929326	0.67	Slc4a4	solute carrier family 4 (anion exchanger), member 4	5356	0.28
chr2_55410377_55410533	0.67	Gm14033	predicted gene 14033	1335	0.54
chr4_155234884_155235204	0.66	Ski	ski sarcoma viral oncogene homolog (avian)	12452	0.15
chr15_4678179_4678596	0.66	C6	complement component 6	48788	0.17
chr19_39212535_39212719	0.66	Cyp2c53-ps	cytochrome P450, family 2, subfamily c, polypeptide 53-ps	16627	0.22
chr7_109519795_109520433	0.65	Snora3	small nucleolar RNA, H/ACA box 3	6	0.9
chr4_139336597_139336796	0.65	AL807811.1	aldo-keto reductase family 7 member A2 (AKR7A2) pseudogene	484	0.54
chr14_41167952_41168199	0.65	Sftpd	surfactant associated protein D	15060	0.1
chr12_76405211_76405366	0.65	Hspa2	heat shock protein 2	879	0.36
chr2_104815840_104816064	0.65	Qser1	glutamine and serine rich 1	744	0.58
chr14_27662763_27662934	0.63	Erc2	ELKS/RAB6-interacting/CAST family member 2	10021	0.24
chr9_106730790_106730941	0.63	Rad54l2	RAD54 like 2 (S. cerevisiae)	7994	0.17
chr2_31463851_31464156	0.63	Ass1	argininosuccinate synthetase 1	6204	0.2
chr2_26913986_26914201	0.62	Surf1	surfeit gene 1	666	0.34
chr5_145877597_145877748	0.62	Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	981	0.52
chr17_56103653_56104012	0.62	Hdgfl2	HDGF like 2	4270	0.1
chr19_37437507_37437930	0.62	Hhex	hematopoietically expressed homeobox	979	0.41
chr5_125174585_125174752	0.61	Ncor2	nuclear receptor co-repressor 2	4385	0.25
chr3_144255664_144255844	0.61	Gm43446	predicted gene 43446	28057	0.16
chr18_12751849_12752025	0.61	Gm7599	predicted gene 7599	8678	0.14
chr15_96687965_96688281	0.61	Slc38a2	solute carrier family 38, member 2	10568	0.16
chr1_40235625_40236062	0.60	Gm38070	predicted gene, 38070	2177	0.32
chr17_56373428_56373598	0.60	Kdm4b	lysine (K)-specific demethylase 4B	1218	0.38
chr9_48820069_48820230	0.60	Zbtb16	zinc finger and BTB domain containing 16	15796	0.23
chr11_45892755_45892939	0.59	Clint1	clathrin interactor 1	10450	0.16
chr12_75475018_75475336	0.59	Gm47690	predicted gene, 47690	33568	0.17
chr14_31614956_31615107	0.59	Hacl1	2-hydroxyacyl-CoA lyase 1	720	0.6
chr10_97000683_97000900	0.59	4930556N09Rik	RIKEN cDNA 4930556N09 gene	34977	0.17
chr3_60858982_60859155	0.59	Gm36985	predicted gene, 36985	1639	0.4
chr16_36988421_36988616	0.59	Fbxo40	F-box protein 40	1949	0.24
chr7_63899068_63899509	0.58	Gm27252	predicted gene 27252	1314	0.37
chr4_97900129_97900314	0.58	Nfia	nuclear factor I/A	10812	0.29
chr5_140818496_140818894	0.58	Gna12	guanine nucleotide binding protein, alpha 12	11462	0.21
chr9_63748321_63748554	0.58	Smad3	SMAD family member 3	2640	0.32
chr7_100475037_100475212	0.58	Gm10603	predicted gene 10603	278	0.81
chr11_120693498_120694122	0.58	Aspscr1	alveolar soft part sarcoma chromosome region, candidate 1 (human)	4500	0.07
chr4_33033624_33033916	0.58	Ube2j1	ubiquitin-conjugating enzyme E2J 1	2242	0.18
chr11_109771773_109771962	0.58	Gm11684	predicted gene 11684	3381	0.21
chr9_104071823_104071974	0.58	Acad11	acyl-Coenzyme A dehydrogenase family, member 11	8165	0.1

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Neurod2_Bhlha15_Bhlhe22_Olig1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.2	0.7	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.2	0.6	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.2	0.8	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.2	0.8	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.1	0.4	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.1	0.6	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1	1.0	GO:0019530	taurine metabolic process(GO:0019530)
0.1	0.4	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	0.5	GO:0032348	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.1	0.8	GO:0006526	arginine biosynthetic process(GO:0006526)
0.1	0.4	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1	0.4	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.1	0.6	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.1	0.3	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.1	0.4	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.2	GO:0046874	quinolinate metabolic process(GO:0046874)
0.1	0.4	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.1	0.3	GO:0032474	otolith morphogenesis(GO:0032474)
0.1	0.3	GO:0035865	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.1	0.3	GO:1901536	regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.1	0.4	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.1	0.3	GO:0061010	gall bladder development(GO:0061010)
0.1	0.3	GO:0061113	pancreas morphogenesis(GO:0061113)
0.1	0.4	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.1	0.3	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.1	0.3	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.2	GO:1902416	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.1	0.2	GO:0032910	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.1	0.4	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.1	0.5	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.4	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.4	GO:0042078	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1	0.6	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.1	0.2	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.1	0.3	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.1	0.3	GO:1903964	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1	0.2	GO:0061511	centriole elongation(GO:0061511)
0.1	0.2	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.1	0.3	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.1	0.2	GO:0015747	urate transport(GO:0015747)
0.1	0.9	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.1	0.2	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)
0.1	0.1	GO:0060128	corticotropin hormone secreting cell differentiation(GO:0060128)
0.1	0.4	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.1	0.1	GO:0018879	biphenyl metabolic process(GO:0018879)
0.1	0.2	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	1.4	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.1	0.1	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.1	0.3	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.1	0.2	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.1	0.2	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.1	0.2	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.1	0.7	GO:0032986	nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.1	0.2	GO:0071896	protein localization to adherens junction(GO:0071896)
0.1	0.3	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.1	0.2	GO:1905005	regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005)
0.1	0.1	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
0.1	0.1	GO:2000259	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1	0.3	GO:0042737	drug catabolic process(GO:0042737)
0.1	0.2	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1	0.3	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.1	0.2	GO:0048162	preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1	0.7	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.1	0.2	GO:0034140	negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.1	0.2	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.3	GO:0043102	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.2	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0	0.1	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.0	0.1	GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.0	0.6	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.1	GO:0002071	glandular epithelial cell maturation(GO:0002071)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.7	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.2	GO:0046836	glycolipid transport(GO:0046836)
0.0	0.7	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.0	0.0	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.0	0.4	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.2	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.2	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0	0.2	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0	0.2	GO:0002155	regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0	0.7	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.3	GO:0042795	snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0	0.1	GO:0015819	lysine transport(GO:0015819)
0.0	0.2	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.3	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.0	0.4	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.0	0.1	GO:1900045	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.1	GO:0071351	cellular response to interleukin-18(GO:0071351)
0.0	0.2	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0	0.2	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0	0.1	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.0	0.2	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	0.5	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.1	GO:0006068	ethanol catabolic process(GO:0006068)
0.0	0.2	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.2	GO:0097460	ferrous iron import into cell(GO:0097460)
0.0	0.1	GO:2000409	positive regulation of T cell extravasation(GO:2000409)
0.0	0.1	GO:0007403	glial cell fate determination(GO:0007403)
0.0	0.1	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.0	0.1	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:1902534	single-organism membrane invagination(GO:1902534)
0.0	0.3	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.1	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0	0.1	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0	0.1	GO:0035523	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.0	0.1	GO:0035459	cargo loading into vesicle(GO:0035459)
0.0	0.1	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.2	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.0	0.1	GO:1900864	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0	0.4	GO:0060294	cilium movement involved in cell motility(GO:0060294)
0.0	0.2	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.2	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.1	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.1	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.3	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0	0.1	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.0	0.1	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.1	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0	0.1	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.0	0.1	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	0.3	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.1	GO:0032849	positive regulation of cellular pH reduction(GO:0032849)
0.0	0.1	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.1	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.1	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0	0.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.4	GO:0038092	nodal signaling pathway(GO:0038092)
0.0	0.1	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0	0.1	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.0	0.1	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.1	GO:0070168	negative regulation of biomineral tissue development(GO:0070168)
0.0	0.0	GO:0097360	chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	1.2	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.1	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.0	GO:2000780	negative regulation of double-strand break repair(GO:2000780)
0.0	0.1	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.1	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.0	GO:0009155	purine deoxyribonucleotide catabolic process(GO:0009155)
0.0	0.1	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.0	0.1	GO:0016321	female meiosis chromosome segregation(GO:0016321)
0.0	0.2	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.2	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.0	0.1	GO:0016139	glycoside catabolic process(GO:0016139)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.5	GO:0060074	synapse maturation(GO:0060074)
0.0	0.1	GO:0090259	regulation of retinal ganglion cell axon guidance(GO:0090259)
0.0	0.2	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.1	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	0.0	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.1	GO:0019720	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.2	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.6	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.2	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.0	0.0	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0	0.1	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	0.1	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
0.0	0.0	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0	0.2	GO:0071420	cellular response to histamine(GO:0071420)
0.0	0.4	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.0	0.0	GO:0036215	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0	0.0	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0	0.1	GO:0090385	phagosome-lysosome fusion(GO:0090385)
0.0	0.1	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.2	GO:0051561	positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0	0.1	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.1	GO:0046098	guanine metabolic process(GO:0046098)
0.0	0.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.0	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0	0.0	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.0	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0	0.1	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.0	0.0	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.0	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	0.1	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.0	0.0	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.0	0.0	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.1	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	0.1	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.0	0.1	GO:0042713	sperm ejaculation(GO:0042713)
0.0	0.1	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0060005	vestibular reflex(GO:0060005)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.1	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.1	GO:0060178	regulation of exocyst localization(GO:0060178)
0.0	0.1	GO:0010624	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.2	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0	0.0	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.1	GO:0019086	late viral transcription(GO:0019086)
0.0	0.1	GO:0035425	autocrine signaling(GO:0035425)
0.0	0.0	GO:1903061	positive regulation of protein lipidation(GO:1903061)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.2	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.0	GO:0070814	hydrogen sulfide biosynthetic process(GO:0070814)
0.0	0.7	GO:0043029	T cell homeostasis(GO:0043029)
0.0	0.1	GO:0070889	platelet alpha granule organization(GO:0070889)
0.0	0.3	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.1	GO:0097623	potassium ion export across plasma membrane(GO:0097623)
0.0	0.1	GO:0010915	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	1.0	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.0	0.0	GO:0061042	vascular wound healing(GO:0061042)
0.0	0.0	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.0	0.0	GO:1902965	regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.2	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.4	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.0	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0	0.0	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0	0.1	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	0.4	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.0	GO:0002840	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0	0.1	GO:0044821	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.1	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.2	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.4	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.1	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.1	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.0	0.0	GO:0051006	positive regulation of lipoprotein lipase activity(GO:0051006)
0.0	0.1	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.0	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.0	GO:0061043	regulation of vascular wound healing(GO:0061043)
0.0	0.3	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.0	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.0	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.0	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.0	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.0	0.1	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.1	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0	0.0	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.1	GO:0060055	angiogenesis involved in wound healing(GO:0060055)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.0	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.0	0.1	GO:0030638	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.1	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.1	GO:0015838	amino-acid betaine transport(GO:0015838)
0.0	0.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.0	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
0.0	0.0	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.0	0.0	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.0	0.1	GO:0006152	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0	0.1	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.0	0.0	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.0	0.1	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.0	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.2	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.0	GO:0006059	hexitol metabolic process(GO:0006059)
0.0	0.4	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.1	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0046886	positive regulation of hormone biosynthetic process(GO:0046886)
0.0	0.2	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.0	GO:0052490	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0	0.1	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.0	GO:0070368	positive regulation of hepatocyte differentiation(GO:0070368)
0.0	0.1	GO:0032754	positive regulation of interleukin-5 production(GO:0032754)
0.0	0.1	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.0	0.1	GO:0010873	positive regulation of cholesterol esterification(GO:0010873)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.0	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.0	GO:2000481	positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0	0.1	GO:1901339	regulation of store-operated calcium channel activity(GO:1901339)
0.0	0.0	GO:0060126	somatotropin secreting cell differentiation(GO:0060126)
0.0	0.1	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	0.3	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.1	GO:0060278	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0	0.1	GO:0007288	sperm axoneme assembly(GO:0007288)
0.0	0.0	GO:0032596	protein transport into membrane raft(GO:0032596)
0.0	0.0	GO:0015884	folic acid transport(GO:0015884)
0.0	0.1	GO:0042659	regulation of cell fate specification(GO:0042659)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0071830	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.0	GO:0035482	gastric motility(GO:0035482)
0.0	0.0	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.0	0.0	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.7	GO:0030500	regulation of bone mineralization(GO:0030500)
0.0	0.0	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.0	0.1	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.0	0.0	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.1	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.1	GO:0006450	regulation of translational fidelity(GO:0006450)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.1	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.1	GO:0021523	somatic motor neuron differentiation(GO:0021523)
0.0	0.1	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.0	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.1	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0	0.0	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.0	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.1	GO:0035337	fatty-acyl-CoA metabolic process(GO:0035337)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.0	0.1	GO:0035357	peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.0	0.1	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.0	0.0	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0	0.1	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.0	0.0	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.0	GO:0090310	negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0	0.2	GO:0099514	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0	0.0	GO:0052405	modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0	0.0	GO:0072061	inner medullary collecting duct development(GO:0072061)
0.0	0.0	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0	0.1	GO:1990845	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0	0.0	GO:0014042	positive regulation of neuron maturation(GO:0014042)
0.0	0.1	GO:0060252	positive regulation of glial cell proliferation(GO:0060252)
0.0	0.1	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
0.0	0.0	GO:0001927	exocyst assembly(GO:0001927)
0.0	0.0	GO:0014056	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056)
0.0	0.1	GO:1904152	regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.0	0.4	GO:0006284	base-excision repair(GO:0006284)
0.0	0.0	GO:0050883	musculoskeletal movement, spinal reflex action(GO:0050883)
0.0	0.0	GO:0046208	spermine catabolic process(GO:0046208)
0.0	0.1	GO:0003416	endochondral bone growth(GO:0003416)
0.0	0.6	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0	0.1	GO:0009813	flavonoid biosynthetic process(GO:0009813) flavonoid glucuronidation(GO:0052696)
0.0	0.0	GO:0009177	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.0	0.0	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.0	0.1	GO:0007097	nuclear migration(GO:0007097)
0.0	0.0	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.0	GO:0032817	regulation of natural killer cell proliferation(GO:0032817)
0.0	0.0	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.0	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.0	GO:0051031	tRNA transport(GO:0051031)
0.0	0.1	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0060384	innervation(GO:0060384)
0.0	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0	0.0	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.3	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.0	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.0	0.0	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.1	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.0	0.0	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
0.0	0.0	GO:0030576	Cajal body organization(GO:0030576)
0.0	0.1	GO:0006622	protein targeting to lysosome(GO:0006622)
0.0	0.0	GO:0045047	protein targeting to ER(GO:0045047)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.0	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.0	GO:0060290	transdifferentiation(GO:0060290)
0.0	0.0	GO:0015888	thiamine transport(GO:0015888)
0.0	0.0	GO:0035330	regulation of hippo signaling(GO:0035330)
0.0	0.1	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.0	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.0	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.0	0.1	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.0	0.0	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.0	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.0	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.0	0.0	GO:0008355	olfactory learning(GO:0008355)
0.0	0.0	GO:0031055	chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.0	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.1	GO:0042095	interferon-gamma biosynthetic process(GO:0042095)
0.0	0.0	GO:0033227	dsRNA transport(GO:0033227)
0.0	0.0	GO:0060956	endocardial cell differentiation(GO:0060956)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0097543	ciliary inversin compartment(GO:0097543)
0.2	0.6	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1	0.4	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	1.4	GO:0030126	COPI vesicle coat(GO:0030126)
0.1	0.4	GO:0034457	Mpp10 complex(GO:0034457)
0.1	0.3	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.1	0.8	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	0.4	GO:0097433	dense body(GO:0097433)
0.1	0.3	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1	0.3	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	0.3	GO:0005642	annulate lamellae(GO:0005642)
0.1	0.7	GO:0030897	HOPS complex(GO:0030897)
0.1	0.3	GO:0071141	SMAD protein complex(GO:0071141)
0.1	0.3	GO:0005579	membrane attack complex(GO:0005579)
0.1	0.4	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1	0.4	GO:0000243	commitment complex(GO:0000243)
0.1	0.2	GO:1990246	uniplex complex(GO:1990246)
0.0	0.8	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.0	0.7	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.1	GO:0030478	actin cap(GO:0030478)
0.0	0.4	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.3	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0005610	laminin-5 complex(GO:0005610)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.2	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0036449	microtubule minus-end(GO:0036449)
0.0	0.3	GO:0070852	cell body fiber(GO:0070852)
0.0	0.4	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.2	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.0	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.1	GO:0005712	chiasma(GO:0005712)
0.0	0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
0.0	0.1	GO:1990111	spermatoproteasome complex(GO:1990111)
0.0	0.2	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.2	GO:0036128	CatSper complex(GO:0036128)
0.0	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0043511	inhibin complex(GO:0043511)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	0.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.1	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.1	GO:0000938	GARP complex(GO:0000938)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0097413	Lewy body(GO:0097413)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.3	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.3	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.6	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.1	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.0	0.0	GO:1990393	3M complex(GO:1990393)
0.0	0.1	GO:1990357	terminal web(GO:1990357)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0045180	basal cortex(GO:0045180)
0.0	1.0	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.1	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.1	GO:0044217	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.2	GO:0010369	chromocenter(GO:0010369)
0.0	0.4	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.8	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.7	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.0	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.2	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.0	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	0.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.1	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.1	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.1	GO:0031298	replication fork protection complex(GO:0031298)
0.0	0.3	GO:0045120	pronucleus(GO:0045120)
0.0	0.3	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0	0.1	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.0	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0	0.0	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.0	0.1	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.4	GO:0031941	filamentous actin(GO:0031941)
0.0	0.9	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	0.1	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	0.0	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.0	GO:0033263	CORVET complex(GO:0033263)
0.0	0.3	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.5	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.6	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.0	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.0	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.0	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0	0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.0	GO:1990423	RZZ complex(GO:1990423)
0.0	0.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.1	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.0	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.0	0.0	GO:1990923	PET complex(GO:1990923)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.2	0.5	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.2	1.4	GO:0016004	phospholipase activator activity(GO:0016004)
0.1	0.4	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1	0.4	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.5	GO:0017040	ceramidase activity(GO:0017040)
0.1	0.3	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.5	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.5	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.1	0.4	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.3	GO:0004046	aminoacylase activity(GO:0004046)
0.1	0.4	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.1	0.2	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	0.3	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.1	0.2	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1	0.2	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	0.2	GO:0019862	IgA binding(GO:0019862)
0.1	0.2	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.1	0.5	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.3	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1	0.4	GO:0031849	olfactory receptor binding(GO:0031849)
0.1	0.5	GO:0035174	histone serine kinase activity(GO:0035174)
0.1	0.2	GO:1990715	mRNA CDS binding(GO:1990715)
0.1	0.2	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	0.3	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.2	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	0.2	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.1	0.2	GO:0071209	U7 snRNA binding(GO:0071209)
0.1	0.2	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1	0.5	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1	0.3	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.4	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	0.3	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.2	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.2	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.6	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.4	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.0	0.7	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.4	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.2	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.3	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0031686	A1 adenosine receptor binding(GO:0031686)
0.0	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.3	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.4	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.7	GO:0032451	demethylase activity(GO:0032451)
0.0	1.1	GO:0043914	NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0	0.1	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0	0.2	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.3	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.2	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.6	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.2	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.3	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.7	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.6	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.4	GO:0043733	alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
0.0	0.1	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.0	0.1	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.3	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.4	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.2	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.1	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.2	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.3	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.0	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.1	GO:0015189	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0	0.4	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0036374	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.0	0.2	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.2	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.2	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.3	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.2	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.0	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.7	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.3	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0045340	mercury ion binding(GO:0045340)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.0	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0	0.1	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0	0.2	GO:0070097	delta-catenin binding(GO:0070097)
0.0	1.3	GO:0008186	ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0	0.3	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.3	GO:0017069	snRNA binding(GO:0017069)
0.0	0.4	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.4	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.0	0.4	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.7	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.3	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.2	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.1	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.5	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	0.1	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.1	GO:0034845	4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.0	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.1	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.2	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.1	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	0.2	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0	0.3	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.0	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.0	GO:0098847	sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.3	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.0	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.0	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.0	0.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.1	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.2	GO:0051861	glycolipid binding(GO:0051861)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.0	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.1	GO:0031720	haptoglobin binding(GO:0031720)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.0	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.0	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.3	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.0	GO:0051765	inositol tetrakisphosphate kinase activity(GO:0051765)
0.0	0.0	GO:0008413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.0	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.0	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.1	GO:0015266	protein channel activity(GO:0015266)
0.0	0.1	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.2	GO:0016662	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662)
0.0	0.0	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.2	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.0	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.0	0.0	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.0	GO:0032190	acrosin binding(GO:0032190)
0.0	0.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.0	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.0	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.0	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0	0.0	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.2	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.0	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.0	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.0	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.0	0.0	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.1	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.0	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.3	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.0	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:1990459	transferrin receptor binding(GO:1990459)
0.0	0.3	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.4	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.0	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.0	0.0	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.0	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.0	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.3	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.2	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.0	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.0	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.1	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.0	0.0	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.0	GO:0042030	ATPase inhibitor activity(GO:0042030)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.9	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.4	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	1.1	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.6	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.2	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.5	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.2	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.5	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.1	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.7	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.2	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	1.0	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.8	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.7	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.9	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.0	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.2	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	0.4	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.3	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.2	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.1	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.3	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.3	PID ATM PATHWAY	ATM pathway
0.0	0.0	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	0.5	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	0.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	0.8	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	1.0	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.5	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.4	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.4	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.3	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.3	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.2	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.4	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.2	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.6	REACTOME ION CHANNEL TRANSPORT	Genes involved in Ion channel transport
0.0	0.4	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.1	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.2	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.1	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.0	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.6	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.2	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.2	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.0	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.3	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.2	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation

Results for Neurod2_Bhlha15_Bhlhe22_Olig1

Z-value: 1.58

Motif logo

Transcription factors associated with Neurod2_Bhlha15_Bhlhe22_Olig1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Neurod2_Bhlha15_Bhlhe22_Olig1 motif across conditions

Conditions sorted by the z-value of the Neurod2_Bhlha15_Bhlhe22_Olig1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Neurod2_Bhlha15_Bhlhe22_Olig1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: