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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Nfat5

Z-value: 2.85

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Transcription factors associated with Nfat5

Gene Symbol	Gene ID	Gene Info
Nfat5 Ensembl NCBI MGI UniProt	ENSMUSG00000003847.10	nuclear factor of activated T cells 5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr8_107323979_107324174	Nfat5	14432	0.186556	-0.97	1.4e-03	Click!
chr8_107293311_107293486	Nfat5	72	0.974562	0.84	3.8e-02	Click!
chr8_107295535_107295732	Nfat5	2074	0.325021	-0.78	6.6e-02	Click!
chr8_107311781_107311960	Nfat5	18311	0.178749	-0.78	6.9e-02	Click!
chr8_107323816_107323969	Nfat5	14616	0.186204	-0.73	1.0e-01	Click!

Activity of the Nfat5 motif across conditions

Conditions sorted by the z-value of the Nfat5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr16_4029500_4029663	2.02	Dnase1	deoxyribonuclease I	7361	0.1
chr6_28681979_28682177	1.98	Snd1	staphylococcal nuclease and tudor domain containing 1	22831	0.21
chrX_166475078_166475249	1.71	Rab9	RAB9, member RAS oncogene family	272	0.87
chr2_114007839_114008018	1.60	A530058N18Rik	RIKEN cDNA A530058N18 gene	5635	0.18
chr12_73739917_73740079	1.54	Gm8075	predicted gene 8075	53485	0.12
chr18_31581248_31581399	1.49	B930094E09Rik	RIKEN cDNA B930094E09 gene	28189	0.14
chr15_27560020_27560329	1.46	Ank	progressive ankylosis	11273	0.16
chr17_34693534_34693687	1.41	Gm24389	predicted gene, 24389	5808	0.07
chr17_84269883_84270034	1.39	Gm24492	predicted gene, 24492	17789	0.18
chr15_97055930_97056081	1.37	Slc38a4	solute carrier family 38, member 4	49	0.99
chr4_57694908_57695066	1.37	Pakap	paralemmin A kinase anchor protein	22670	0.21
chr4_86655537_86655697	1.37	Plin2	perilipin 2	3027	0.23
chr12_8336736_8336921	1.35	Gm48071	predicted gene, 48071	111	0.96
chr5_65731676_65731850	1.34	N4bp2os	NEDD4 binding protein 2, opposite strand	31594	0.08
chr8_10857392_10857567	1.33	Gm32540	predicted gene, 32540	8707	0.12
chr6_5496841_5497314	1.33	Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	768	0.76
chr7_109729230_109729394	1.29	Ascl3	achaete-scute family bHLH transcription factor 3	2414	0.16
chr4_141540912_141541063	1.29	Spen	spen family transcription repressor	2390	0.2
chr8_116867427_116867600	1.28	Cmc2	COX assembly mitochondrial protein 2	27011	0.17
chr12_21143230_21143533	1.24	Asap2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	31427	0.16
chr15_97184306_97184490	1.24	Gm32885	predicted gene, 32885	17154	0.22
chr1_127014601_127014752	1.23	Gm5261	predicted gene 5261	36020	0.21
chr5_75320369_75320658	1.23	Gm18345	predicted gene, 18345	21930	0.17
chr4_134483768_134483942	1.23	Gm13250	predicted gene 13250	9367	0.1
chr9_83575574_83575734	1.21	Sh3bgrl2	SH3 domain binding glutamic acid-rich protein like 2	1177	0.44
chr4_129102568_129102940	1.21	Tmem54	transmembrane protein 54	2794	0.17
chr2_7245751_7245902	1.21	Gm24340	predicted gene, 24340	104271	0.08
chr17_49225348_49225539	1.20	Gm9586	predicted gene 9586	59685	0.11
chr11_58225731_58226335	1.14	Gm5038	predicted gene 5038	5417	0.12
chr12_69451221_69451390	1.13	5830428M24Rik	RIKEN cDNA 5830428M24 gene	16087	0.15
chr6_121880488_121880790	1.11	Mug1	murinoglobulin 1	4938	0.21
chr14_30011884_30012221	1.11	Chdh	choline dehydrogenase	2881	0.15
chr6_142451263_142451444	1.10	Gys2	glycogen synthase 2	21756	0.15
chr11_107373329_107373545	1.09	Gm11712	predicted gene 11712	13546	0.13
chr3_152208280_152208431	1.08	Dnajb4	DnaJ heat shock protein family (Hsp40) member B4	1664	0.24
chr19_7040189_7040358	1.08	Stip1	stress-induced phosphoprotein 1	306	0.79
chr10_59786429_59786610	1.07	Gm17059	predicted gene 17059	13735	0.14
chr15_41232850_41233023	1.07	Gm49529	predicted gene, 49529	10222	0.28
chr11_89999415_89999783	1.07	Pctp	phosphatidylcholine transfer protein	3295	0.3
chr10_40103741_40104111	1.04	Gm25613	predicted gene, 25613	5536	0.16
chr10_17411654_17411805	1.04	Gm47760	predicted gene, 47760	78852	0.09
chr16_50752281_50752456	1.04	Dubr	Dppa2 upstream binding RNA	19595	0.17
chr4_107307141_107307306	1.03	Dio1	deiodinase, iodothyronine, type I	54	0.96
chr10_99285837_99286030	1.03	Gm48089	predicted gene, 48089	11137	0.12
chr7_73720957_73721108	1.02	Gm45007	predicted gene 45007	14492	0.09
chr12_52442391_52442588	1.02	Gm47431	predicted gene, 47431	5636	0.23
chr16_23993594_23993884	1.02	Bcl6	B cell leukemia/lymphoma 6	4887	0.18
chr10_87524634_87525254	1.02	Pah	phenylalanine hydroxylase	2917	0.27
chr14_18963381_18963542	1.02	Gm6785	predicted gene 6785	52476	0.09
chr13_93890136_93890314	1.02	Gm25534	predicted gene, 25534	33086	0.15
chr19_60970416_60970579	1.00	Gm9529	predicted gene 9529	3245	0.25
chr6_147064387_147064568	1.00	Mrps35	mitochondrial ribosomal protein S35	3226	0.17
chr14_47354165_47354327	0.98	Lgals3	lectin, galactose binding, soluble 3	13505	0.1
chr5_77135206_77135376	0.98	Chaer1	cardiac hypertrophy associated epigenetic regulator 1	4961	0.15
chr14_48715168_48715320	0.97	Gm49153	predicted gene, 49153	11060	0.1
chr11_49754996_49755172	0.97	Gm23813	predicted gene, 23813	16749	0.12
chr10_127915625_127915914	0.97	Gm15905	predicted gene 15905	5300	0.1
chr10_111060737_111060938	0.96	Gm48851	predicted gene, 48851	42034	0.12
chr17_31401280_31401456	0.96	Pde9a	phosphodiesterase 9A	12788	0.13
chr13_36324738_36325087	0.96	Fars2	phenylalanine-tRNA synthetase 2 (mitochondrial)	2046	0.39
chr1_23484410_23484576	0.96	Gm7784	predicted gene 7784	4954	0.27
chr5_90441310_90441504	0.96	Alb	albumin	19490	0.15
chr6_99153668_99154006	0.95	Foxp1	forkhead box P1	9181	0.29
chr18_84038085_84038236	0.95	Tshz1	teashirt zinc finger family member 1	46915	0.11
chr2_156451427_156451737	0.95	Gm14225	predicted gene 14225	3974	0.13
chr9_48618198_48618386	0.95	Nnmt	nicotinamide N-methyltransferase	13139	0.24
chr15_38914094_38914399	0.94	Baalc	brain and acute leukemia, cytoplasmic	18898	0.16
chr10_18066229_18066412	0.93	Reps1	RalBP1 associated Eps domain containing protein	10316	0.2
chr1_184060517_184060686	0.93	Dusp10	dual specificity phosphatase 10	26220	0.19
chrX_60288366_60288543	0.92	Atp11c	ATPase, class VI, type 11C	21624	0.19
chr13_45475320_45475484	0.91	Gm23387	predicted gene, 23387	10928	0.21
chr2_90503158_90503454	0.91	4933423P22Rik	RIKEN cDNA 4933423P22 gene	24056	0.16
chr6_31100129_31100294	0.90	Gm13833	predicted gene 13833	2635	0.17
chr12_8217539_8217881	0.90	Gm33037	predicted gene, 33037	8545	0.19
chr14_8030613_8030794	0.89	Abhd6	abhydrolase domain containing 6	27737	0.14
chr7_112217221_112217373	0.88	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	8559	0.27
chr2_46521470_46521692	0.88	Gm13470	predicted gene 13470	78871	0.1
chr17_5822578_5822749	0.88	Gm26595	predicted gene, 26595	5191	0.15
chr14_103796960_103797130	0.88	Ednrb	endothelin receptor type B	46650	0.16
chr1_93444863_93445044	0.88	Hdlbp	high density lipoprotein (HDL) binding protein	479	0.73
chr19_24140621_24140924	0.88	Tjp2	tight junction protein 2	2310	0.26
chr17_31075588_31075765	0.87	Gm25447	predicted gene, 25447	16072	0.12
chr5_122541967_122542146	0.87	Ift81	intraflagellar transport 81	18785	0.1
chr12_84165735_84165922	0.87	Elmsan1	ELM2 and Myb/SANT-like domain containing 1	5690	0.11
chr10_8881801_8881995	0.87	Gm26674	predicted gene, 26674	2739	0.21
chr10_95726009_95726178	0.86	1110019B22Rik	RIKEN cDNA 1110019B22 gene	3593	0.14
chr2_133533395_133533563	0.86	Bmp2	bone morphogenetic protein 2	18680	0.18
chr15_67146457_67146648	0.86	St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	17529	0.24
chr11_118132374_118132525	0.86	Dnah17	dynein, axonemal, heavy chain 17	1815	0.31
chr7_140971847_140972117	0.86	Ifitm1	interferon induced transmembrane protein 1	3942	0.09
chr13_81314862_81315034	0.85	Adgrv1	adhesion G protein-coupled receptor V1	27888	0.21
chr4_82506086_82506263	0.85	Nfib	nuclear factor I/B	395	0.83
chr16_24403826_24403991	0.85	Gm24440	predicted gene, 24440	2509	0.25
chr7_45494671_45494867	0.84	Nucb1	nucleobindin 1	4069	0.07
chr6_121303535_121303719	0.84	Slc6a13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13	2845	0.19
chr4_134632478_134632661	0.84	Mir6403	microRNA 6403	64718	0.08
chr2_114775678_114775838	0.84	Gm13975	predicted gene 13975	67646	0.11
chr1_119293927_119294093	0.84	Gm29456	predicted gene 29456	32823	0.15
chr4_76460810_76460979	0.83	Gm42303	predicted gene, 42303	9663	0.22
chr10_75121130_75121291	0.83	Bcr	BCR activator of RhoGEF and GTPase	39150	0.15
chr14_58511744_58511934	0.83	Gm25614	predicted gene, 25614	138561	0.05
chr12_25222158_25222309	0.83	Gm47705	predicted gene, 47705	40465	0.13
chr12_57538421_57538660	0.82	Foxa1	forkhead box A1	7581	0.15
chr2_162975863_162976054	0.82	Gm11453	predicted gene 11453	7303	0.13
chr9_62560095_62560276	0.81	Coro2b	coronin, actin binding protein, 2B	23141	0.2
chr5_137673193_137673366	0.80	Agfg2	ArfGAP with FG repeats 2	8963	0.08
chr6_88254247_88254414	0.80	1700031F10Rik	RIKEN cDNA 1700031F10 gene	28652	0.12
chr15_97019476_97019938	0.80	Slc38a4	solute carrier family 38, member 4	244	0.95
chr6_92874895_92875055	0.80	Gm15737	predicted gene 15737	5618	0.21
chr1_190044023_190044190	0.78	Smyd2	SET and MYND domain containing 2	121743	0.05
chr1_84399988_84400148	0.78	Gm37959	predicted gene, 37959	4669	0.28
chr9_96413135_96413443	0.78	BC043934	cDNA sequence BC043934	24145	0.14
chr16_32570471_32570637	0.78	Gm34680	predicted gene, 34680	18812	0.13
chr13_45662593_45662744	0.77	Gm47460	predicted gene, 47460	86904	0.09
chr11_8525657_8525830	0.77	Tns3	tensin 3	19608	0.28
chr4_109138749_109138940	0.77	Osbpl9	oxysterol binding protein-like 9	17766	0.2
chr3_102678642_102678802	0.77	Gm19202	predicted gene, 19202	7995	0.15
chr4_140421599_140421768	0.77	Gm13021	predicted gene 13021	841	0.54
chr13_81334264_81334446	0.77	Adgrv1	adhesion G protein-coupled receptor V1	8481	0.28
chr18_20663466_20663626	0.77	Gm16090	predicted gene 16090	1714	0.28
chr6_145759082_145759277	0.76	Rassf8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8	8608	0.2
chr10_99215027_99215178	0.76	Gm34574	predicted gene, 34574	7964	0.12
chr13_60417568_60417726	0.75	Gm35333	predicted gene, 35333	9551	0.2
chr4_138065715_138066098	0.75	Eif4g3	eukaryotic translation initiation factor 4 gamma, 3	61154	0.1
chr5_136966368_136966667	0.75	Cldn15	claudin 15	99	0.93
chr16_25963962_25964122	0.75	Gm4524	predicted gene 4524	7567	0.24
chr1_5084443_5084619	0.75	Atp6v1h	ATPase, H+ transporting, lysosomal V1 subunit H	1367	0.41
chr11_7190101_7190311	0.75	Ccdc201	coiled coil domain 201	1637	0.34
chr16_22898238_22898714	0.75	Ahsg	alpha-2-HS-glycoprotein	3612	0.14
chr11_86870593_86870759	0.74	Dhx40	DEAH (Asp-Glu-Ala-His) box polypeptide 40	62930	0.1
chr1_180248872_180249054	0.73	Psen2	presenilin 2	813	0.55
chr2_90497646_90497817	0.73	4933423P22Rik	RIKEN cDNA 4933423P22 gene	18481	0.17
chr12_8676206_8676575	0.73	Pum2	pumilio RNA-binding family member 2	1144	0.56
chr1_103762005_103762338	0.72	Gm37789	predicted gene, 37789	37826	0.24
chr18_4335718_4335869	0.72	Map3k8	mitogen-activated protein kinase kinase kinase 8	502	0.73
chr15_73535706_73535919	0.71	Dennd3	DENN/MADD domain containing 3	11678	0.18
chr19_42018681_42018835	0.71	Ubtd1	ubiquitin domain containing 1	1609	0.24
chr1_105361150_105361318	0.71	Gm17634	predicted gene, 17634	4085	0.21
chr7_46839028_46839384	0.71	Ldha	lactate dehydrogenase A	2269	0.15
chr6_17497396_17497805	0.71	Met	met proto-oncogene	6359	0.25
chr1_46908404_46908555	0.71	Gm28527	predicted gene 28527	11600	0.18
chr17_24646006_24646165	0.71	Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	1095	0.25
chr7_3145518_3145669	0.71	Gm29708	predicted gene, 29708	4398	0.09
chr12_99187779_99187941	0.71	4930474N09Rik	RIKEN cDNA 4930474N09 gene	25052	0.17
chr5_8877204_8877378	0.70	Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	16426	0.14
chr11_50354656_50355246	0.70	Cby3	chibby family member 3	489	0.68
chr14_48503805_48503964	0.69	Tmem260	transmembrane protein 260	2102	0.24
chr15_99416114_99416265	0.69	Gm49483	predicted gene, 49483	2715	0.14
chr7_48998714_48998914	0.69	Nav2	neuron navigator 2	39717	0.13
chr12_111450305_111450614	0.68	Tnfaip2	tumor necrosis factor, alpha-induced protein 2	60	0.96
chr17_67989309_67989497	0.68	Arhgap28	Rho GTPase activating protein 28	14717	0.27
chr18_15491588_15491739	0.68	Aqp4	aquaporin 4	80681	0.09
chr13_112189619_112189791	0.68	Gm48802	predicted gene, 48802	17637	0.17
chr1_77233176_77233341	0.68	Gm38265	predicted gene, 38265	86266	0.09
chr6_56765406_56765619	0.68	Avl9	AVL9 cell migration associated	24599	0.13
chr11_67579194_67579345	0.67	Gm12301	predicted gene 12301	1803	0.38
chr4_144956318_144956685	0.67	Gm38074	predicted gene, 38074	2347	0.3
chr11_98586121_98586288	0.66	Ormdl3	ORM1-like 3 (S. cerevisiae)	1164	0.32
chr8_105820252_105820414	0.66	Ranbp10	RAN binding protein 10	6872	0.09
chr15_78448062_78448253	0.66	Tmprss6	transmembrane serine protease 6	3778	0.12
chr6_13052374_13052732	0.66	Gm5300	predicted gene 5300	4044	0.25
chr9_78027220_78027380	0.65	Gm47829	predicted gene, 47829	645	0.57
chr8_114563440_114563727	0.65	Gm16116	predicted gene 16116	31317	0.18
chr19_3361014_3361165	0.65	Cpt1a	carnitine palmitoyltransferase 1a, liver	5241	0.15
chr1_156751907_156752178	0.65	Fam20b	family with sequence similarity 20, member B	32956	0.12
chr10_12781594_12781823	0.65	Gm23044	predicted gene, 23044	12266	0.22
chr5_120643717_120643868	0.65	Gm42657	predicted gene 42657	2171	0.14
chr1_131473746_131474085	0.65	Gm24273	predicted gene, 24273	24887	0.12
chr2_34963005_34963156	0.65	Traf1	TNF receptor-associated factor 1	1308	0.28
chr19_29470771_29470965	0.64	Pdcd1lg2	programmed cell death 1 ligand 2	48809	0.1
chr4_48196773_48196961	0.64	Erp44	endoplasmic reticulum protein 44	157	0.96
chr6_122921546_122921699	0.64	Clec4a1	C-type lectin domain family 4, member a1	226	0.9
chr14_41160885_41161053	0.63	Mbl1	mannose-binding lectin (protein A) 1	9468	0.11
chr11_98750923_98751087	0.63	Thra	thyroid hormone receptor alpha	2581	0.15
chr3_94512708_94512862	0.62	Snx27	sorting nexin family member 27	6306	0.09
chr5_139371537_139372089	0.62	Mir339	microRNA 339	2068	0.2
chr19_5815107_5815391	0.62	Gm27702	predicted gene, 27702	9458	0.07
chr16_27390173_27390573	0.62	Ccdc50	coiled-coil domain containing 50	405	0.86
chr5_139343215_139343377	0.62	Cox19	cytochrome c oxidase assembly protein 19	1829	0.23
chr13_112192610_112192944	0.62	Gm48802	predicted gene, 48802	20709	0.16
chr4_34566308_34566519	0.61	Orc3	origin recognition complex, subunit 3	10483	0.17
chr2_29664156_29664347	0.61	Rapgef1	Rap guanine nucleotide exchange factor (GEF) 1	20436	0.17
chrX_100470864_100471043	0.61	Igbp1	immunoglobulin (CD79A) binding protein 1	23338	0.13
chr7_112369157_112369454	0.61	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	997	0.66
chr12_82333304_82333465	0.61	Sipa1l1	signal-induced proliferation-associated 1 like 1	8883	0.29
chr18_56451778_56452171	0.61	Gramd3	GRAM domain containing 3	17293	0.18
chr17_11460661_11461013	0.61	Gm28118	predicted gene 28118	84961	0.1
chr6_39191456_39191621	0.61	Kdm7a	lysine (K)-specific demethylase 7A	15251	0.14
chr16_23135545_23135714	0.60	Gm49624	predicted gene, 49624	1309	0.19
chr5_110795558_110795763	0.60	Ulk1	unc-51 like kinase 1	137	0.93
chr12_91637193_91637441	0.60	Gm47804	predicted gene, 47804	19640	0.15
chr10_78351630_78352005	0.59	Agpat3	1-acylglycerol-3-phosphate O-acyltransferase 3	48	0.9
chr5_65157811_65158257	0.59	Klhl5	kelch-like 5	1964	0.29
chr14_105941342_105941672	0.59	Spry2	sprouty RTK signaling antagonist 2	44688	0.16
chr9_45085678_45085847	0.59	Jaml	junction adhesion molecule like	727	0.46
chr16_72734333_72734499	0.59	Robo1	roundabout guidance receptor 1	71212	0.14
chr8_117344375_117344531	0.59	Cmip	c-Maf inducing protein	4717	0.29
chr1_74012711_74012960	0.59	Tns1	tensin 1	3587	0.28
chr5_98719262_98719413	0.59	Bmp3	bone morphogenetic protein 3	135078	0.05
chr7_138868386_138868561	0.58	Ppp2r2d	protein phosphatase 2, regulatory subunit B, delta	63	0.96

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfat5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.6	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.3	1.0	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2	0.6	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.2	0.7	GO:0060486	Clara cell differentiation(GO:0060486)
0.1	0.4	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.1	0.2	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1	0.6	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.5	GO:0048496	maintenance of organ identity(GO:0048496)
0.1	0.2	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.1	0.4	GO:0007296	vitellogenesis(GO:0007296)
0.1	0.4	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.3	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.1	0.3	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.1	2.6	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.1	0.2	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.1	0.2	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
0.1	0.2	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1	0.2	GO:1901856	negative regulation of cellular respiration(GO:1901856)
0.1	0.3	GO:0032345	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.1	0.3	GO:0051661	maintenance of centrosome location(GO:0051661)
0.1	0.2	GO:0015744	succinate transport(GO:0015744)
0.1	0.2	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1	0.2	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.1	0.5	GO:0021707	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1	0.1	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.1	0.3	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.1	0.4	GO:0007220	Notch receptor processing(GO:0007220)
0.1	0.2	GO:0019086	late viral transcription(GO:0019086)
0.1	0.2	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1	0.2	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.1	0.3	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	0.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.2	GO:1903011	negative regulation of bone development(GO:1903011)
0.1	0.3	GO:0042118	endothelial cell activation(GO:0042118)
0.1	0.2	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1	0.3	GO:1902222	L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1	0.3	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.2	GO:0007525	somatic muscle development(GO:0007525)
0.1	0.3	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.1	0.2	GO:1903061	positive regulation of protein lipidation(GO:1903061)
0.1	0.2	GO:0072402	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1	0.2	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1	0.6	GO:0051601	exocyst localization(GO:0051601)
0.1	0.1	GO:1901859	negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.1	0.2	GO:2000667	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0	0.2	GO:0014063	negative regulation of serotonin secretion(GO:0014063)
0.0	0.1	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.3	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.1	GO:0048320	axial mesoderm formation(GO:0048320)
0.0	0.1	GO:0002434	immune complex clearance(GO:0002434)
0.0	0.2	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0	0.1	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0	0.1	GO:0038171	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.3	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0061144	alveolar secondary septum development(GO:0061144)
0.0	0.4	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.0	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.3	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.0	0.0	GO:0051795	positive regulation of catagen(GO:0051795)
0.0	0.1	GO:0061535	glutamate secretion, neurotransmission(GO:0061535)
0.0	0.2	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.6	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.3	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.1	GO:1902512	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0	0.1	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.1	GO:0034436	glycoprotein transport(GO:0034436)
0.0	0.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.1	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.1	GO:0008050	female courtship behavior(GO:0008050)
0.0	0.1	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.1	GO:0036394	amylase secretion(GO:0036394)
0.0	0.1	GO:0046016	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.0	0.4	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.1	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.0	0.1	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0	0.2	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.0	0.1	GO:0036233	glycine import(GO:0036233)
0.0	0.2	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.1	GO:0010025	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0	0.0	GO:0070460	thyroid-stimulating hormone secretion(GO:0070460) negative regulation of response to alcohol(GO:1901420)
0.0	0.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.1	GO:2000977	regulation of forebrain neuron differentiation(GO:2000977)
0.0	0.1	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210)
0.0	0.2	GO:0030913	paranodal junction assembly(GO:0030913)
0.0	0.2	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0	0.2	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.1	GO:0070295	renal water absorption(GO:0070295)
0.0	0.1	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.0	0.4	GO:0006144	purine nucleobase metabolic process(GO:0006144)
0.0	0.2	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.0	0.0	GO:2000019	negative regulation of male gonad development(GO:2000019)
0.0	0.1	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.1	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.1	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.1	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.1	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.0	0.1	GO:0090148	membrane fission(GO:0090148)
0.0	0.1	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
0.0	0.2	GO:1901841	regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0	0.2	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.0	0.2	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.0	0.1	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636)
0.0	0.1	GO:0046075	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.4	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.1	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.0	0.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.9	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.1	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0	0.5	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0002461	tolerance induction dependent upon immune response(GO:0002461)
0.0	0.1	GO:2000327	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0	0.1	GO:0051025	negative regulation of immunoglobulin secretion(GO:0051025)
0.0	0.0	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0	0.1	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.0	0.0	GO:0060166	olfactory pit development(GO:0060166)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.2	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.0	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.2	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.1	GO:0018904	ether metabolic process(GO:0018904)
0.0	0.0	GO:0046881	positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.4	GO:0003351	epithelial cilium movement(GO:0003351)
0.0	0.0	GO:0034770	histone H4-K20 methylation(GO:0034770)
0.0	0.1	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.1	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0071351	cellular response to interleukin-18(GO:0071351)
0.0	0.1	GO:0001692	histamine metabolic process(GO:0001692)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.2	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.0	0.0	GO:0060268	negative regulation of respiratory burst(GO:0060268)
0.0	0.1	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045)
0.0	0.1	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.0	0.1	GO:0071332	cellular response to fructose stimulus(GO:0071332)
0.0	0.1	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.2	GO:0033572	transferrin transport(GO:0033572)
0.0	0.1	GO:0045472	response to ether(GO:0045472)
0.0	0.0	GO:0021943	formation of radial glial scaffolds(GO:0021943)
0.0	0.0	GO:0021776	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0	0.1	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.0	GO:0060128	corticotropin hormone secreting cell differentiation(GO:0060128)
0.0	0.0	GO:0072053	renal inner medulla development(GO:0072053)
0.0	0.1	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.0	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.0	0.1	GO:0060613	fat pad development(GO:0060613)
0.0	0.2	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.0	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.0	0.1	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0	0.2	GO:0036035	osteoclast development(GO:0036035)
0.0	0.0	GO:0097694	establishment of RNA localization to telomere(GO:0097694)
0.0	0.0	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0	0.3	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.0	GO:0071899	regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.3	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.0	GO:0048819	regulation of hair follicle maturation(GO:0048819)
0.0	0.8	GO:0042446	hormone biosynthetic process(GO:0042446)
0.0	0.2	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0071918	urea transmembrane transport(GO:0071918)
0.0	0.2	GO:0002329	pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0042706	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0	0.0	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	0.0	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.0	0.1	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.1	GO:1903999	negative regulation of eating behavior(GO:1903999)
0.0	0.1	GO:0046040	IMP metabolic process(GO:0046040)
0.0	0.0	GO:0033058	directional locomotion(GO:0033058)
0.0	0.2	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.1	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.0	GO:0033505	floor plate morphogenesis(GO:0033505)
0.0	0.0	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0	0.1	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.3	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.1	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.1	GO:2000291	regulation of myoblast proliferation(GO:2000291)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.0	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.0	0.0	GO:2000040	regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.0	0.1	GO:0009436	glyoxylate catabolic process(GO:0009436)
0.0	0.1	GO:0006532	aspartate biosynthetic process(GO:0006532)
0.0	0.1	GO:0090232	positive regulation of spindle checkpoint(GO:0090232)
0.0	0.0	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.0	0.1	GO:0090238	positive regulation of arachidonic acid secretion(GO:0090238)
0.0	0.1	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0	0.1	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.0	GO:0015766	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.0	GO:1990168	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	0.0	GO:0046136	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0	0.1	GO:0009092	homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
0.0	0.0	GO:1902308	regulation of peptidyl-serine dephosphorylation(GO:1902308)
0.0	0.0	GO:0009756	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.0	0.0	GO:0001907	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.0	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.0	GO:0035992	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0	0.1	GO:0070474	positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0	0.0	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242)
0.0	0.0	GO:0032789	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.0	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
0.0	0.1	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0	0.0	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.0	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
0.0	0.1	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.0	0.0	GO:0035928	rRNA import into mitochondrion(GO:0035928)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.0	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
0.0	0.0	GO:0090335	regulation of brown fat cell differentiation(GO:0090335)
0.0	0.0	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0	0.1	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.1	GO:0070431	nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0	0.1	GO:0038202	TORC1 signaling(GO:0038202) regulation of TORC1 signaling(GO:1903432) negative regulation of TORC1 signaling(GO:1904262)
0.0	0.1	GO:0050915	sensory perception of sour taste(GO:0050915)
0.0	0.0	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.8	GO:0030500	regulation of bone mineralization(GO:0030500)
0.0	0.1	GO:0097264	self proteolysis(GO:0097264)
0.0	0.2	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.1	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.0	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.0	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.2	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.0	GO:0060323	head morphogenesis(GO:0060323)
0.0	0.0	GO:2000338	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0	0.1	GO:0009437	carnitine metabolic process(GO:0009437)
0.0	0.1	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.0	0.0	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.0	0.2	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.0	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	0.2	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0035995	detection of muscle stretch(GO:0035995)
0.0	0.0	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0	0.2	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.0	0.0	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533)
0.0	0.2	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.0	GO:2000402	negative regulation of lymphocyte migration(GO:2000402)
0.0	0.1	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.0	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0	0.1	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0030953	astral microtubule organization(GO:0030953)
0.0	0.0	GO:0003162	atrioventricular node development(GO:0003162)
0.0	0.1	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.0	0.4	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.1	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.0	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.1	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
0.0	0.1	GO:0060763	mammary duct terminal end bud growth(GO:0060763)
0.0	0.0	GO:0006285	base-excision repair, AP site formation(GO:0006285)
0.0	0.1	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.0	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.0	GO:0097527	necroptotic signaling pathway(GO:0097527)
0.0	0.0	GO:0035262	gonad morphogenesis(GO:0035262)
0.0	0.0	GO:2000409	positive regulation of T cell extravasation(GO:2000409)
0.0	0.0	GO:1990169	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0	0.0	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0	0.0	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.0	GO:0060988	lipid tube assembly(GO:0060988)
0.0	0.0	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.0	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.0	GO:0032570	response to progesterone(GO:0032570)
0.0	0.0	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.0	0.0	GO:0071873	response to norepinephrine(GO:0071873)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.0	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0	0.0	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.1	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.0	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.0	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.0	0.0	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.1	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	0.0	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.0	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.0	0.0	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0	0.0	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.0	0.1	GO:0045724	positive regulation of cilium assembly(GO:0045724)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.0	GO:0097503	sialylation(GO:0097503)
0.0	0.3	GO:0061001	regulation of dendritic spine morphogenesis(GO:0061001)
0.0	0.0	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.0	0.4	GO:0019915	lipid storage(GO:0019915)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0042953	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0	0.0	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
0.0	0.1	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.0	GO:0099624	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0	0.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.0	GO:2000520	regulation of immunological synapse formation(GO:2000520)
0.0	0.2	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.0	GO:0060455	negative regulation of gastric acid secretion(GO:0060455)
0.0	0.0	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.0	GO:1901679	nucleotide transmembrane transport(GO:1901679)
0.0	0.1	GO:0033866	coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0	0.0	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.0	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.1	GO:0032691	negative regulation of interleukin-1 beta production(GO:0032691)
0.0	0.1	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.0	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0	0.0	GO:0061152	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0	0.1	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.0	0.0	GO:0061724	lipophagy(GO:0061724)
0.0	0.0	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.0	GO:1901660	calcium ion export(GO:1901660)
0.0	0.0	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.0	GO:0015819	lysine transport(GO:0015819)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.1	0.4	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.4	GO:0097433	dense body(GO:0097433)
0.1	0.2	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.1	0.5	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.1	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.1	0.4	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1	0.4	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.1	0.2	GO:1990246	uniplex complex(GO:1990246)
0.1	0.2	GO:0035339	SPOTS complex(GO:0035339)
0.0	0.1	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
0.0	0.4	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.2	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.6	GO:0000145	exocyst(GO:0000145)
0.0	0.3	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.2	GO:0000243	commitment complex(GO:0000243)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.3	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.6	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.1	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.0	0.2	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.2	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.3	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0044299	C-fiber(GO:0044299)
0.0	0.3	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	1.1	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.1	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.4	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.1	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.1	GO:0031261	DNA replication preinitiation complex(GO:0031261)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.0	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.1	GO:1990462	omegasome(GO:1990462)
0.0	0.1	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.1	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0	0.1	GO:0002177	manchette(GO:0002177)
0.0	0.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.6	GO:0005921	gap junction(GO:0005921)
0.0	0.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.7	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.2	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.0	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.0	GO:0032127	dense core granule membrane(GO:0032127)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.7	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.1	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.1	GO:0020003	symbiont-containing vacuole(GO:0020003)
0.0	0.0	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.1	GO:0097255	R2TP complex(GO:0097255)
0.0	0.0	GO:0031523	Myb complex(GO:0031523)
0.0	0.0	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	1.4	GO:0072562	blood microparticle(GO:0072562)
0.0	0.2	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.2	GO:0031011	Ino80 complex(GO:0031011)
0.0	0.0	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.0	GO:0042627	chylomicron(GO:0042627)
0.0	0.0	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.0	0.0	GO:0005879	axonemal microtubule(GO:0005879)
0.0	0.0	GO:0035838	growing cell tip(GO:0035838)
0.0	0.0	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.4	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.0	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.1	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.1	GO:0097542	ciliary tip(GO:0097542)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.3	1.0	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2	0.5	GO:0070573	metallodipeptidase activity(GO:0070573)
0.2	0.5	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	0.4	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	0.3	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1	0.3	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.1	0.4	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	0.3	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.1	0.4	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.2	GO:0015141	succinate transmembrane transporter activity(GO:0015141)
0.1	0.5	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1	0.2	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.1	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.1	0.2	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.1	0.2	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.1	0.2	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1	0.3	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.6	GO:0004016	adenylate cyclase activity(GO:0004016)
0.1	0.3	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.4	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1	0.5	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.1	0.2	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1	0.4	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.2	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.0	0.1	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.2	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.4	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.3	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.0	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.4	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
0.0	0.1	GO:0048030	disaccharide binding(GO:0048030)
0.0	0.2	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.3	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	0.3	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.5	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.9	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.2	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.2	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	1.7	GO:0019003	GDP binding(GO:0019003)
0.0	0.4	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.2	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0004854	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.2	GO:0018634	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0	0.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.2	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.2	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.2	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.3	GO:0017166	vinculin binding(GO:0017166)
0.0	0.6	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.6	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0015265	urea channel activity(GO:0015265)
0.0	0.3	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.0	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.0	0.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	0.1	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0000182	rDNA binding(GO:0000182)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0071209	U7 snRNA binding(GO:0071209)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.3	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.9	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.1	GO:0009041	uridylate kinase activity(GO:0009041)
0.0	0.5	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.2	GO:0044213	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.4	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.0	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:1990932	5.8S rRNA binding(GO:1990932)
0.0	0.1	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	0.0	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.4	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.2	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
0.0	0.1	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.3	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.2	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.0	GO:0008515	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.2	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	0.3	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0001013	RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.0	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.0	0.0	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.3	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.3	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.1	GO:0034594	phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.0	0.3	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0016453	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0	0.1	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
0.0	0.0	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.2	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.0	GO:0019959	interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.0	0.0	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.0	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0	0.0	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.0	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0015250	water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.0	0.1	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.0	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.0	GO:0018636	phenanthrene 9,10-monooxygenase activity(GO:0018636)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.3	GO:0061650	ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.0	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.0	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0032557	pyrimidine ribonucleotide binding(GO:0032557)
0.0	0.1	GO:0034869	2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.0	0.2	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:1990405	protein antigen binding(GO:1990405)
0.0	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.0	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.0	0.1	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.0	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.1	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.0	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.3	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.0	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0034573	protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.0	0.0	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0	0.0	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.5	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.0	0.0	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.0	0.1	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.0	0.1	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	0.0	GO:0042731	PH domain binding(GO:0042731)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	0.2	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.6	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.1	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.2	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.2	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	1.4	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.4	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.2	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.0	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.1	PID FOXO PATHWAY	FoxO family signaling
0.0	0.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.1	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.0	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.4	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.1	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	0.7	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.7	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.4	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.2	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.4	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.0	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.3	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.1	PID EPHB FWD PATHWAY	EPHB forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	0.9	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.4	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.1	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.2	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.9	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.6	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.5	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.4	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.1	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.2	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.1	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.1	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.3	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.2	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.5	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.0	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.1	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.2	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling

Results for Nfat5

Z-value: 2.85

Motif logo

Transcription factors associated with Nfat5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Nfat5 motif across conditions

Conditions sorted by the z-value of the Nfat5 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfat5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: