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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Nfat5

Z-value: 2.85

Motif logo

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Transcription factors associated with Nfat5

Gene Symbol Gene ID Gene Info
ENSMUSG00000003847.10 Nfat5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

GenePromoterDistanceAssociation probabilityPearson corr. coef.P-valuePlot
Nfat5chr8_107323979_107324174144320.186556-0.971.4e-03Click!
Nfat5chr8_107293311_107293486720.9745620.843.8e-02Click!
Nfat5chr8_107295535_10729573220740.325021-0.786.6e-02Click!
Nfat5chr8_107311781_107311960183110.178749-0.786.9e-02Click!
Nfat5chr8_107323816_107323969146160.186204-0.731.0e-01Click!

Activity of the Nfat5 motif across conditions

Conditions sorted by the z-value of the Nfat5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr16_4029500_4029663 2.02 Dnase1
deoxyribonuclease I
7361
0.1
chr6_28681979_28682177 1.98 Snd1
staphylococcal nuclease and tudor domain containing 1
22831
0.21
chrX_166475078_166475249 1.71 Rab9
RAB9, member RAS oncogene family
272
0.87
chr2_114007839_114008018 1.60 A530058N18Rik
RIKEN cDNA A530058N18 gene
5635
0.18
chr12_73739917_73740079 1.54 Gm8075
predicted gene 8075
53485
0.12
chr18_31581248_31581399 1.49 B930094E09Rik
RIKEN cDNA B930094E09 gene
28189
0.14
chr15_27560020_27560329 1.46 Ank
progressive ankylosis
11273
0.16
chr17_34693534_34693687 1.41 Gm24389
predicted gene, 24389
5808
0.07
chr17_84269883_84270034 1.39 Gm24492
predicted gene, 24492
17789
0.18
chr15_97055930_97056081 1.37 Slc38a4
solute carrier family 38, member 4
49
0.99
chr4_57694908_57695066 1.37 Pakap
paralemmin A kinase anchor protein
22670
0.21
chr4_86655537_86655697 1.37 Plin2
perilipin 2
3027
0.23
chr12_8336736_8336921 1.35 Gm48071
predicted gene, 48071
111
0.96
chr5_65731676_65731850 1.34 N4bp2os
NEDD4 binding protein 2, opposite strand
31594
0.08
chr8_10857392_10857567 1.33 Gm32540
predicted gene, 32540
8707
0.12
chr6_5496841_5497314 1.33 Pdk4
pyruvate dehydrogenase kinase, isoenzyme 4
768
0.76
chr7_109729230_109729394 1.29 Ascl3
achaete-scute family bHLH transcription factor 3
2414
0.16
chr4_141540912_141541063 1.29 Spen
spen family transcription repressor
2390
0.2
chr8_116867427_116867600 1.28 Cmc2
COX assembly mitochondrial protein 2
27011
0.17
chr12_21143230_21143533 1.24 Asap2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
31427
0.16
chr15_97184306_97184490 1.24 Gm32885
predicted gene, 32885
17154
0.22
chr1_127014601_127014752 1.23 Gm5261
predicted gene 5261
36020
0.21
chr5_75320369_75320658 1.23 Gm18345
predicted gene, 18345
21930
0.17
chr4_134483768_134483942 1.23 Gm13250
predicted gene 13250
9367
0.1
chr9_83575574_83575734 1.21 Sh3bgrl2
SH3 domain binding glutamic acid-rich protein like 2
1177
0.44
chr4_129102568_129102940 1.21 Tmem54
transmembrane protein 54
2794
0.17
chr2_7245751_7245902 1.21 Gm24340
predicted gene, 24340
104271
0.08
chr17_49225348_49225539 1.20 Gm9586
predicted gene 9586
59685
0.11
chr11_58225731_58226335 1.14 Gm5038
predicted gene 5038
5417
0.12
chr12_69451221_69451390 1.13 5830428M24Rik
RIKEN cDNA 5830428M24 gene
16087
0.15
chr6_121880488_121880790 1.11 Mug1
murinoglobulin 1
4938
0.21
chr14_30011884_30012221 1.11 Chdh
choline dehydrogenase
2881
0.15
chr6_142451263_142451444 1.10 Gys2
glycogen synthase 2
21756
0.15
chr11_107373329_107373545 1.09 Gm11712
predicted gene 11712
13546
0.13
chr3_152208280_152208431 1.08 Dnajb4
DnaJ heat shock protein family (Hsp40) member B4
1664
0.24
chr19_7040189_7040358 1.08 Stip1
stress-induced phosphoprotein 1
306
0.79
chr10_59786429_59786610 1.07 Gm17059
predicted gene 17059
13735
0.14
chr15_41232850_41233023 1.07 Gm49529
predicted gene, 49529
10222
0.28
chr11_89999415_89999783 1.07 Pctp
phosphatidylcholine transfer protein
3295
0.3
chr10_40103741_40104111 1.04 Gm25613
predicted gene, 25613
5536
0.16
chr10_17411654_17411805 1.04 Gm47760
predicted gene, 47760
78852
0.09
chr16_50752281_50752456 1.04 Dubr
Dppa2 upstream binding RNA
19595
0.17
chr4_107307141_107307306 1.03 Dio1
deiodinase, iodothyronine, type I
54
0.96
chr10_99285837_99286030 1.03 Gm48089
predicted gene, 48089
11137
0.12
chr7_73720957_73721108 1.02 Gm45007
predicted gene 45007
14492
0.09
chr12_52442391_52442588 1.02 Gm47431
predicted gene, 47431
5636
0.23
chr16_23993594_23993884 1.02 Bcl6
B cell leukemia/lymphoma 6
4887
0.18
chr10_87524634_87525254 1.02 Pah
phenylalanine hydroxylase
2917
0.27
chr14_18963381_18963542 1.02 Gm6785
predicted gene 6785
52476
0.09
chr13_93890136_93890314 1.02 Gm25534
predicted gene, 25534
33086
0.15
chr19_60970416_60970579 1.00 Gm9529
predicted gene 9529
3245
0.25
chr6_147064387_147064568 1.00 Mrps35
mitochondrial ribosomal protein S35
3226
0.17
chr14_47354165_47354327 0.98 Lgals3
lectin, galactose binding, soluble 3
13505
0.1
chr5_77135206_77135376 0.98 Chaer1
cardiac hypertrophy associated epigenetic regulator 1
4961
0.15
chr14_48715168_48715320 0.97 Gm49153
predicted gene, 49153
11060
0.1
chr11_49754996_49755172 0.97 Gm23813
predicted gene, 23813
16749
0.12
chr10_127915625_127915914 0.97 Gm15905
predicted gene 15905
5300
0.1
chr10_111060737_111060938 0.96 Gm48851
predicted gene, 48851
42034
0.12
chr17_31401280_31401456 0.96 Pde9a
phosphodiesterase 9A
12788
0.13
chr13_36324738_36325087 0.96 Fars2
phenylalanine-tRNA synthetase 2 (mitochondrial)
2046
0.39
chr1_23484410_23484576 0.96 Gm7784
predicted gene 7784
4954
0.27
chr5_90441310_90441504 0.96 Alb
albumin
19490
0.15
chr6_99153668_99154006 0.95 Foxp1
forkhead box P1
9181
0.29
chr18_84038085_84038236 0.95 Tshz1
teashirt zinc finger family member 1
46915
0.11
chr2_156451427_156451737 0.95 Gm14225
predicted gene 14225
3974
0.13
chr9_48618198_48618386 0.95 Nnmt
nicotinamide N-methyltransferase
13139
0.24
chr15_38914094_38914399 0.94 Baalc
brain and acute leukemia, cytoplasmic
18898
0.16
chr10_18066229_18066412 0.93 Reps1
RalBP1 associated Eps domain containing protein
10316
0.2
chr1_184060517_184060686 0.93 Dusp10
dual specificity phosphatase 10
26220
0.19
chrX_60288366_60288543 0.92 Atp11c
ATPase, class VI, type 11C
21624
0.19
chr13_45475320_45475484 0.91 Gm23387
predicted gene, 23387
10928
0.21
chr2_90503158_90503454 0.91 4933423P22Rik
RIKEN cDNA 4933423P22 gene
24056
0.16
chr6_31100129_31100294 0.90 Gm13833
predicted gene 13833
2635
0.17
chr12_8217539_8217881 0.90 Gm33037
predicted gene, 33037
8545
0.19
chr14_8030613_8030794 0.89 Abhd6
abhydrolase domain containing 6
27737
0.14
chr7_112217221_112217373 0.88 Mical2
microtubule associated monooxygenase, calponin and LIM domain containing 2
8559
0.27
chr2_46521470_46521692 0.88 Gm13470
predicted gene 13470
78871
0.1
chr17_5822578_5822749 0.88 Gm26595
predicted gene, 26595
5191
0.15
chr14_103796960_103797130 0.88 Ednrb
endothelin receptor type B
46650
0.16
chr1_93444863_93445044 0.88 Hdlbp
high density lipoprotein (HDL) binding protein
479
0.73
chr19_24140621_24140924 0.88 Tjp2
tight junction protein 2
2310
0.26
chr17_31075588_31075765 0.87 Gm25447
predicted gene, 25447
16072
0.12
chr5_122541967_122542146 0.87 Ift81
intraflagellar transport 81
18785
0.1
chr12_84165735_84165922 0.87 Elmsan1
ELM2 and Myb/SANT-like domain containing 1
5690
0.11
chr10_8881801_8881995 0.87 Gm26674
predicted gene, 26674
2739
0.21
chr10_95726009_95726178 0.86 1110019B22Rik
RIKEN cDNA 1110019B22 gene
3593
0.14
chr2_133533395_133533563 0.86 Bmp2
bone morphogenetic protein 2
18680
0.18
chr15_67146457_67146648 0.86 St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
17529
0.24
chr11_118132374_118132525 0.86 Dnah17
dynein, axonemal, heavy chain 17
1815
0.31
chr7_140971847_140972117 0.86 Ifitm1
interferon induced transmembrane protein 1
3942
0.09
chr13_81314862_81315034 0.85 Adgrv1
adhesion G protein-coupled receptor V1
27888
0.21
chr4_82506086_82506263 0.85 Nfib
nuclear factor I/B
395
0.83
chr16_24403826_24403991 0.85 Gm24440
predicted gene, 24440
2509
0.25
chr7_45494671_45494867 0.84 Nucb1
nucleobindin 1
4069
0.07
chr6_121303535_121303719 0.84 Slc6a13
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
2845
0.19
chr4_134632478_134632661 0.84 Mir6403
microRNA 6403
64718
0.08
chr2_114775678_114775838 0.84 Gm13975
predicted gene 13975
67646
0.11
chr1_119293927_119294093 0.84 Gm29456
predicted gene 29456
32823
0.15
chr4_76460810_76460979 0.83 Gm42303
predicted gene, 42303
9663
0.22
chr10_75121130_75121291 0.83 Bcr
BCR activator of RhoGEF and GTPase
39150
0.15
chr14_58511744_58511934 0.83 Gm25614
predicted gene, 25614
138561
0.05
chr12_25222158_25222309 0.83 Gm47705
predicted gene, 47705
40465
0.13
chr12_57538421_57538660 0.82 Foxa1
forkhead box A1
7581
0.15
chr2_162975863_162976054 0.82 Gm11453
predicted gene 11453
7303
0.13
chr9_62560095_62560276 0.81 Coro2b
coronin, actin binding protein, 2B
23141
0.2
chr5_137673193_137673366 0.80 Agfg2
ArfGAP with FG repeats 2
8963
0.08
chr6_88254247_88254414 0.80 1700031F10Rik
RIKEN cDNA 1700031F10 gene
28652
0.12
chr15_97019476_97019938 0.80 Slc38a4
solute carrier family 38, member 4
244
0.95
chr6_92874895_92875055 0.80 Gm15737
predicted gene 15737
5618
0.21
chr1_190044023_190044190 0.78 Smyd2
SET and MYND domain containing 2
121743
0.05
chr1_84399988_84400148 0.78 Gm37959
predicted gene, 37959
4669
0.28
chr9_96413135_96413443 0.78 BC043934
cDNA sequence BC043934
24145
0.14
chr16_32570471_32570637 0.78 Gm34680
predicted gene, 34680
18812
0.13
chr13_45662593_45662744 0.77 Gm47460
predicted gene, 47460
86904
0.09
chr11_8525657_8525830 0.77 Tns3
tensin 3
19608
0.28
chr4_109138749_109138940 0.77 Osbpl9
oxysterol binding protein-like 9
17766
0.2
chr3_102678642_102678802 0.77 Gm19202
predicted gene, 19202
7995
0.15
chr4_140421599_140421768 0.77 Gm13021
predicted gene 13021
841
0.54
chr13_81334264_81334446 0.77 Adgrv1
adhesion G protein-coupled receptor V1
8481
0.28
chr18_20663466_20663626 0.77 Gm16090
predicted gene 16090
1714
0.28
chr6_145759082_145759277 0.76 Rassf8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
8608
0.2
chr10_99215027_99215178 0.76 Gm34574
predicted gene, 34574
7964
0.12
chr13_60417568_60417726 0.75 Gm35333
predicted gene, 35333
9551
0.2
chr4_138065715_138066098 0.75 Eif4g3
eukaryotic translation initiation factor 4 gamma, 3
61154
0.1
chr5_136966368_136966667 0.75 Cldn15
claudin 15
99
0.93
chr16_25963962_25964122 0.75 Gm4524
predicted gene 4524
7567
0.24
chr1_5084443_5084619 0.75 Atp6v1h
ATPase, H+ transporting, lysosomal V1 subunit H
1367
0.41
chr11_7190101_7190311 0.75 Ccdc201
coiled coil domain 201
1637
0.34
chr16_22898238_22898714 0.75 Ahsg
alpha-2-HS-glycoprotein
3612
0.14
chr11_86870593_86870759 0.74 Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
62930
0.1
chr1_180248872_180249054 0.73 Psen2
presenilin 2
813
0.55
chr2_90497646_90497817 0.73 4933423P22Rik
RIKEN cDNA 4933423P22 gene
18481
0.17
chr12_8676206_8676575 0.73 Pum2
pumilio RNA-binding family member 2
1144
0.56
chr1_103762005_103762338 0.72 Gm37789
predicted gene, 37789
37826
0.24
chr18_4335718_4335869 0.72 Map3k8
mitogen-activated protein kinase kinase kinase 8
502
0.73
chr15_73535706_73535919 0.71 Dennd3
DENN/MADD domain containing 3
11678
0.18
chr19_42018681_42018835 0.71 Ubtd1
ubiquitin domain containing 1
1609
0.24
chr1_105361150_105361318 0.71 Gm17634
predicted gene, 17634
4085
0.21
chr7_46839028_46839384 0.71 Ldha
lactate dehydrogenase A
2269
0.15
chr6_17497396_17497805 0.71 Met
met proto-oncogene
6359
0.25
chr1_46908404_46908555 0.71 Gm28527
predicted gene 28527
11600
0.18
chr17_24646006_24646165 0.71 Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
1095
0.25
chr7_3145518_3145669 0.71 Gm29708
predicted gene, 29708
4398
0.09
chr12_99187779_99187941 0.71 4930474N09Rik
RIKEN cDNA 4930474N09 gene
25052
0.17
chr5_8877204_8877378 0.70 Abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
16426
0.14
chr11_50354656_50355246 0.70 Cby3
chibby family member 3
489
0.68
chr14_48503805_48503964 0.69 Tmem260
transmembrane protein 260
2102
0.24
chr15_99416114_99416265 0.69 Gm49483
predicted gene, 49483
2715
0.14
chr7_48998714_48998914 0.69 Nav2
neuron navigator 2
39717
0.13
chr12_111450305_111450614 0.68 Tnfaip2
tumor necrosis factor, alpha-induced protein 2
60
0.96
chr17_67989309_67989497 0.68 Arhgap28
Rho GTPase activating protein 28
14717
0.27
chr18_15491588_15491739 0.68 Aqp4
aquaporin 4
80681
0.09
chr13_112189619_112189791 0.68 Gm48802
predicted gene, 48802
17637
0.17
chr1_77233176_77233341 0.68 Gm38265
predicted gene, 38265
86266
0.09
chr6_56765406_56765619 0.68 Avl9
AVL9 cell migration associated
24599
0.13
chr11_67579194_67579345 0.67 Gm12301
predicted gene 12301
1803
0.38
chr4_144956318_144956685 0.67 Gm38074
predicted gene, 38074
2347
0.3
chr11_98586121_98586288 0.66 Ormdl3
ORM1-like 3 (S. cerevisiae)
1164
0.32
chr8_105820252_105820414 0.66 Ranbp10
RAN binding protein 10
6872
0.09
chr15_78448062_78448253 0.66 Tmprss6
transmembrane serine protease 6
3778
0.12
chr6_13052374_13052732 0.66 Gm5300
predicted gene 5300
4044
0.25
chr9_78027220_78027380 0.65 Gm47829
predicted gene, 47829
645
0.57
chr8_114563440_114563727 0.65 Gm16116
predicted gene 16116
31317
0.18
chr19_3361014_3361165 0.65 Cpt1a
carnitine palmitoyltransferase 1a, liver
5241
0.15
chr1_156751907_156752178 0.65 Fam20b
family with sequence similarity 20, member B
32956
0.12
chr10_12781594_12781823 0.65 Gm23044
predicted gene, 23044
12266
0.22
chr5_120643717_120643868 0.65 Gm42657
predicted gene 42657
2171
0.14
chr1_131473746_131474085 0.65 Gm24273
predicted gene, 24273
24887
0.12
chr2_34963005_34963156 0.65 Traf1
TNF receptor-associated factor 1
1308
0.28
chr19_29470771_29470965 0.64 Pdcd1lg2
programmed cell death 1 ligand 2
48809
0.1
chr4_48196773_48196961 0.64 Erp44
endoplasmic reticulum protein 44
157
0.96
chr6_122921546_122921699 0.64 Clec4a1
C-type lectin domain family 4, member a1
226
0.9
chr14_41160885_41161053 0.63 Mbl1
mannose-binding lectin (protein A) 1
9468
0.11
chr11_98750923_98751087 0.63 Thra
thyroid hormone receptor alpha
2581
0.15
chr3_94512708_94512862 0.62 Snx27
sorting nexin family member 27
6306
0.09
chr5_139371537_139372089 0.62 Mir339
microRNA 339
2068
0.2
chr19_5815107_5815391 0.62 Gm27702
predicted gene, 27702
9458
0.07
chr16_27390173_27390573 0.62 Ccdc50
coiled-coil domain containing 50
405
0.86
chr5_139343215_139343377 0.62 Cox19
cytochrome c oxidase assembly protein 19
1829
0.23
chr13_112192610_112192944 0.62 Gm48802
predicted gene, 48802
20709
0.16
chr4_34566308_34566519 0.61 Orc3
origin recognition complex, subunit 3
10483
0.17
chr2_29664156_29664347 0.61 Rapgef1
Rap guanine nucleotide exchange factor (GEF) 1
20436
0.17
chrX_100470864_100471043 0.61 Igbp1
immunoglobulin (CD79A) binding protein 1
23338
0.13
chr7_112369157_112369454 0.61 Mical2
microtubule associated monooxygenase, calponin and LIM domain containing 2
997
0.66
chr12_82333304_82333465 0.61 Sipa1l1
signal-induced proliferation-associated 1 like 1
8883
0.29
chr18_56451778_56452171 0.61 Gramd3
GRAM domain containing 3
17293
0.18
chr17_11460661_11461013 0.61 Gm28118
predicted gene 28118
84961
0.1
chr6_39191456_39191621 0.61 Kdm7a
lysine (K)-specific demethylase 7A
15251
0.14
chr16_23135545_23135714 0.60 Gm49624
predicted gene, 49624
1309
0.19
chr5_110795558_110795763 0.60 Ulk1
unc-51 like kinase 1
137
0.93
chr12_91637193_91637441 0.60 Gm47804
predicted gene, 47804
19640
0.15
chr10_78351630_78352005 0.59 Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
48
0.9
chr5_65157811_65158257 0.59 Klhl5
kelch-like 5
1964
0.29
chr14_105941342_105941672 0.59 Spry2
sprouty RTK signaling antagonist 2
44688
0.16
chr9_45085678_45085847 0.59 Jaml
junction adhesion molecule like
727
0.46
chr16_72734333_72734499 0.59 Robo1
roundabout guidance receptor 1
71212
0.14
chr8_117344375_117344531 0.59 Cmip
c-Maf inducing protein
4717
0.29
chr1_74012711_74012960 0.59 Tns1
tensin 1
3587
0.28
chr5_98719262_98719413 0.59 Bmp3
bone morphogenetic protein 3
135078
0.05
chr7_138868386_138868561 0.58 Ppp2r2d
protein phosphatase 2, regulatory subunit B, delta
63
0.96

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Nfat5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.3 1.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2 0.6 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 0.7 GO:0060486 Clara cell differentiation(GO:0060486)
0.1 0.4 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.1 0.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.6 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.5 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.2 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.4 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 0.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 2.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.2 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.2 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.1 0.3 GO:0032345 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.1 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.2 GO:0015744 succinate transport(GO:0015744)
0.1 0.2 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.2 GO:1902564 negative regulation of neutrophil activation(GO:1902564)
0.1 0.5 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.1 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.2 GO:0019086 late viral transcription(GO:0019086)
0.1 0.2 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.2 GO:0019249 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.1 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.2 GO:1903011 negative regulation of bone development(GO:1903011)
0.1 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.3 GO:1902222 L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.2 GO:1903061 positive regulation of protein lipidation(GO:1903061)
0.1 0.2 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.2 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 0.6 GO:0051601 exocyst localization(GO:0051601)
0.1 0.1 GO:1901859 negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.1 0.2 GO:2000667 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0 0.2 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.0 0.1 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.0 0.1 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0048320 axial mesoderm formation(GO:0048320)
0.0 0.1 GO:0002434 immune complex clearance(GO:0002434)
0.0 0.2 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.1 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0 0.1 GO:0038171 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0061144 alveolar secondary septum development(GO:0061144)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.0 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.1 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.1 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0 0.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.1 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:0036394 amylase secretion(GO:0036394)
0.0 0.1 GO:0046016 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.0 0.4 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.1 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.2 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.0 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.1 GO:2000977 regulation of forebrain neuron differentiation(GO:2000977)
0.0 0.1 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.0 0.2 GO:0030913 paranodal junction assembly(GO:0030913)
0.0 0.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.0 0.4 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.0 GO:2000019 negative regulation of male gonad development(GO:2000019)
0.0 0.1 GO:0061643 chemorepulsion of axon(GO:0061643)
0.0 0.1 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:0090148 membrane fission(GO:0090148)
0.0 0.1 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.0 0.2 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.1 GO:0046075 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.9 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0002461 tolerance induction dependent upon immune response(GO:0002461)
0.0 0.1 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.1 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.0 0.0 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.0 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.0 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0018904 ether metabolic process(GO:0018904)
0.0 0.0 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.4 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.0 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.0 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0071351 cellular response to interleukin-18(GO:0071351)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.0 GO:0060268 negative regulation of respiratory burst(GO:0060268)
0.0 0.1 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.0 0.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0071332 cellular response to fructose stimulus(GO:0071332)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.2 GO:0033572 transferrin transport(GO:0033572)
0.0 0.1 GO:0045472 response to ether(GO:0045472)
0.0 0.0 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.0 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.0 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.0 0.0 GO:0072053 renal inner medulla development(GO:0072053)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.0 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.0 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.0 0.1 GO:1990036 calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0 0.2 GO:0036035 osteoclast development(GO:0036035)
0.0 0.0 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
0.0 0.0 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.0 GO:0071899 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.0 GO:0048819 regulation of hair follicle maturation(GO:0048819)
0.0 0.8 GO:0042446 hormone biosynthetic process(GO:0042446)
0.0 0.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.0 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.0 GO:0006714 sesquiterpenoid metabolic process(GO:0006714)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.1 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.0 0.1 GO:0046040 IMP metabolic process(GO:0046040)
0.0 0.0 GO:0033058 directional locomotion(GO:0033058)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:0033505 floor plate morphogenesis(GO:0033505)
0.0 0.0 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.1 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 0.1 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.0 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.0 GO:2000040 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.0 0.1 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.1 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.1 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.0 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.1 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.1 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.0 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.0 GO:1990168 protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0 0.0 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.1 GO:0009092 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
0.0 0.0 GO:1902308 regulation of peptidyl-serine dephosphorylation(GO:1902308)
0.0 0.0 GO:0009756 carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.0 0.0 GO:0001907 killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0 0.0 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.0 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.1 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0 0.0 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.0 GO:0032789 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0 0.0 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.1 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.0 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.1 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.0 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.0 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.0 GO:0090335 regulation of brown fat cell differentiation(GO:0090335)
0.0 0.0 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0070431 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0 0.1 GO:0038202 TORC1 signaling(GO:0038202) regulation of TORC1 signaling(GO:1903432) negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.0 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.8 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.0 GO:0006553 lysine metabolic process(GO:0006553)
0.0 0.0 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.0 GO:0060323 head morphogenesis(GO:0060323)
0.0 0.0 GO:2000338 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0 0.1 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.1 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.0 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.0 GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.2 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.0 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.2 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.0 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.2 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.0 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.0 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.0 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.4 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.0 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.0 0.1 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.0 0.0 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.1 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.0 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.0 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.0 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 0.0 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.0 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0 0.0 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.0 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.0 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.0 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0 0.0 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.0 GO:0032570 response to progesterone(GO:0032570)
0.0 0.0 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.0 GO:0071873 response to norepinephrine(GO:0071873)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.0 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.0 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.0 0.1 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.0 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.0 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.0 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.0 GO:1903525 regulation of membrane tubulation(GO:1903525)
0.0 0.0 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.0 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.1 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.0 GO:0097503 sialylation(GO:0097503)
0.0 0.3 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.0 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.0 0.4 GO:0019915 lipid storage(GO:0019915)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.0 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.1 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.0 GO:0099624 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0 0.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.0 GO:2000520 regulation of immunological synapse formation(GO:2000520)
0.0 0.2 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.0 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.0 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.0 GO:1901679 nucleotide transmembrane transport(GO:1901679)
0.0 0.1 GO:0033866 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0032691 negative regulation of interleukin-1 beta production(GO:0032691)
0.0 0.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.0 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.0 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.0 GO:0061724 lipophagy(GO:0061724)
0.0 0.0 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.0 GO:1901660 calcium ion export(GO:1901660)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.0 GO:0015819 lysine transport(GO:0015819)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.1 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.4 GO:0097433 dense body(GO:0097433)
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.4 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.1 0.2 GO:1990246 uniplex complex(GO:1990246)
0.1 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0044299 C-fiber(GO:0044299)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.0 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.0 0.1 GO:1990462 omegasome(GO:1990462)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.0 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.0 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.1 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.0 0.0 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.0 GO:0031523 Myb complex(GO:0031523)
0.0 0.0 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 1.4 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.0 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.0 GO:0042627 chylomicron(GO:0042627)
0.0 0.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.0 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.0 GO:0035838 growing cell tip(GO:0035838)
0.0 0.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.0 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.3 1.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.5 GO:0070573 metallodipeptidase activity(GO:0070573)
0.2 0.5 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.3 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.2 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.1 0.2 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.1 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.3 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.5 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.1 0.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.2 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.1 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.0 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 1.7 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0004854 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.2 GO:0018634 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.0 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.0 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.0 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0004942 anaphylatoxin receptor activity(GO:0004942)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.0 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.0 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.0 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.1 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.0 0.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0 0.1 GO:0004779 sulfate adenylyltransferase activity(GO:0004779)
0.0 0.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.0 0.0 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.0 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.0 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0015250 water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.0 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.0 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.3 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0032557 pyrimidine ribonucleotide binding(GO:0032557)
0.0 0.1 GO:0034869 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.0 0.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.0 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.0 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.0 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.0 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0034573 protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.0 0.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.5 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.0 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.0 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 0.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.1 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.0 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.1 PID FOXO PATHWAY FoxO family signaling
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.0 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.3 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 PID EPHB FWD PATHWAY EPHB forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.1 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.0 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.5 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.0 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling