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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Nfatc3

Z-value: 1.28

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Transcription factors associated with Nfatc3

Gene Symbol	Gene ID	Gene Info
Nfatc3 Ensembl NCBI MGI UniProt	ENSMUSG00000031902.9	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr8_106060353_106060504	Nfatc3	795	0.476272	-0.77	7.4e-02	Click!
chr8_106059327_106059509	Nfatc3	215	0.883995	0.62	1.9e-01	Click!
chr8_106074066_106074226	Nfatc3	14513	0.105236	0.57	2.4e-01	Click!
chr8_106059647_106060341	Nfatc3	361	0.777977	0.44	3.8e-01	Click!
chr8_106069760_106069911	Nfatc3	10202	0.109261	-0.35	5.0e-01	Click!

Activity of the Nfatc3 motif across conditions

Conditions sorted by the z-value of the Nfatc3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr19_46140539_46140690	1.05	Pitx3	paired-like homeodomain transcription factor 3	369	0.79
chr18_46720026_46720377	0.98	Cdo1	cysteine dioxygenase 1, cytosolic	7828	0.13
chr4_144956318_144956685	0.96	Gm38074	predicted gene, 38074	2347	0.3
chr9_43225133_43225294	0.94	Oaf	out at first homolog	121	0.95
chr19_42601924_42602199	0.80	Loxl4	lysyl oxidase-like 4	1260	0.45
chr13_93625401_93625555	0.80	Gm15622	predicted gene 15622	96	0.96
chr10_8089089_8089240	0.80	Gm48614	predicted gene, 48614	67872	0.11
chr15_89377019_89377232	0.76	Tymp	thymidine phosphorylase	86	0.89
chr1_72145974_72146125	0.67	Gm4319	predicted gene 4319	24048	0.15
chr2_153656760_153657071	0.64	Dnmt3bos	DNA methyltransferase 3B, opposite strand	6629	0.16
chr3_83006212_83006467	0.64	Fgg	fibrinogen gamma chain	1385	0.32
chr2_33274814_33274965	0.64	Gm13537	predicted gene 13537	48282	0.11
chr16_76242740_76242921	0.63	Nrip1	nuclear receptor interacting protein 1	80828	0.08
chr11_75211079_75211230	0.60	Rtn4rl1	reticulon 4 receptor-like 1	17371	0.1
chr15_97019476_97019938	0.58	Slc38a4	solute carrier family 38, member 4	244	0.95
chr19_42610535_42610705	0.58	Loxl4	lysyl oxidase-like 4	2089	0.31
chr19_42891636_42891940	0.58	Hps1	HPS1, biogenesis of lysosomal organelles complex 3 subunit 1	111810	0.06
chr1_133257148_133257349	0.55	Gm19461	predicted gene, 19461	130	0.89
chr3_37934934_37935257	0.54	Gm7799	predicted gene 7799	24992	0.14
chr12_52442391_52442588	0.53	Gm47431	predicted gene, 47431	5636	0.23
chr9_43467603_43467754	0.53	Gm28215	predicted gene 28215	1744	0.35
chr7_87222899_87223055	0.51	Gm6230	predicted gene 6230	19908	0.21
chr1_131969813_131969968	0.50	Slc45a3	solute carrier family 45, member 3	719	0.55
chr3_132917768_132917922	0.50	Npnt	nephronectin	11486	0.16
chr10_121428648_121428803	0.49	Gm18730	predicted gene, 18730	28012	0.1
chr12_80107632_80107989	0.49	Zfp36l1	zinc finger protein 36, C3H type-like 1	5184	0.14
chr9_65288876_65289027	0.49	Clpx	caseinolytic mitochondrial matrix peptidase chaperone subunit	5309	0.12
chr5_64712724_64712894	0.49	Gm20033	predicted gene, 20033	1640	0.32
chr8_105820252_105820414	0.49	Ranbp10	RAN binding protein 10	6872	0.09
chr2_103844031_103844275	0.49	Gm13879	predicted gene 13879	497	0.45
chr17_29496086_29496540	0.49	Pim1	proviral integration site 1	2906	0.15
chr5_105112436_105112587	0.48	Gbp9	guanylate-binding protein 9	2234	0.28
chr8_35417280_35417458	0.47	Gm45301	predicted gene 45301	7863	0.17
chr12_109988784_109988986	0.47	Gm34667	predicted gene, 34667	34988	0.09
chr12_21143230_21143533	0.47	Asap2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	31427	0.16
chr8_10968601_10968792	0.47	Gm44956	predicted gene 44956	2118	0.2
chr5_8962552_8962757	0.46	Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	4102	0.15
chr10_68355501_68355861	0.46	4930545H06Rik	RIKEN cDNA 4930545H06 gene	34539	0.17
chr10_122384642_122385270	0.45	Gm36041	predicted gene, 36041	1936	0.39
chr18_75180173_75180522	0.45	Gm8807	predicted gene 8807	2467	0.32
chr4_33257682_33258147	0.45	Pnrc1	proline-rich nuclear receptor coactivator 1	9404	0.17
chr5_139872154_139872313	0.44	Gm42423	predicted gene 42423	23576	0.12
chr4_141826031_141826198	0.44	Cela2a	chymotrypsin-like elastase family, member 2A	46	0.95
chr3_118507933_118508602	0.44	Gm37773	predicted gene, 37773	17884	0.14
chr5_121858862_121859046	0.44	Cux2	cut-like homeobox 2	7109	0.11
chr13_98595769_98595925	0.43	Gm4815	predicted gene 4815	17654	0.12
chr12_4583826_4584201	0.42	Gm48610	predicted gene, 48610	7257	0.13
chr16_4029500_4029663	0.42	Dnase1	deoxyribonuclease I	7361	0.1
chr19_41449775_41450079	0.41	Gm9788	predicted pseudogene 9788	9886	0.21
chr10_95583008_95583178	0.41	Nudt4	nudix (nucleoside diphosphate linked moiety X)-type motif 4	18947	0.12
chr11_19962395_19962565	0.41	Spred2	sprouty-related EVH1 domain containing 2	7910	0.28
chr17_23675280_23675431	0.41	Tnfrsf12a	tumor necrosis factor receptor superfamily, member 12a	1198	0.16
chr6_126035696_126035896	0.41	Ntf3	neurotrophin 3	129164	0.05
chr18_20938375_20938560	0.41	Rnf125	ring finger protein 125	6158	0.22
chr16_91762844_91763094	0.41	Itsn1	intersectin 1 (SH3 domain protein 1A)	6870	0.17
chr9_21807212_21807383	0.40	Mir7083	microRNA 7083	2703	0.15
chr19_46639707_46639916	0.40	Wbp1l	WW domain binding protein 1 like	16410	0.12
chr4_44985654_44986028	0.40	Grhpr	glyoxylate reductase/hydroxypyruvate reductase	4341	0.13
chrX_166475078_166475249	0.40	Rab9	RAB9, member RAS oncogene family	272	0.87
chr2_38378853_38379004	0.39	Gm13584	predicted gene 13584	14948	0.14
chr10_63248712_63248888	0.39	Gm19337	predicted gene, 19337	2132	0.19
chr12_85748786_85748937	0.39	Flvcr2	feline leukemia virus subgroup C cellular receptor 2	2322	0.22
chr9_103064909_103065087	0.39	Gm47468	predicted gene, 47468	20528	0.14
chr7_112202260_112202451	0.39	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	23501	0.22
chr13_102877226_102877399	0.39	Mast4	microtubule associated serine/threonine kinase family member 4	28474	0.23
chr13_73730823_73730977	0.39	Slc12a7	solute carrier family 12, member 7	2194	0.26
chr15_10248990_10249545	0.39	Prlr	prolactin receptor	293	0.94
chr15_66951818_66951981	0.39	Ndrg1	N-myc downstream regulated gene 1	3420	0.21
chr3_69120460_69120611	0.39	Gm37558	predicted gene, 37558	2189	0.22
chr1_58475966_58476117	0.38	Orc2	origin recognition complex, subunit 2	5408	0.13
chr6_121874198_121874349	0.38	Mug1	murinoglobulin 1	11304	0.19
chr1_39192739_39192927	0.38	Npas2	neuronal PAS domain protein 2	898	0.59
chr14_70338039_70338256	0.38	Slc39a14	solute carrier family 39 (zinc transporter), member 14	3949	0.15
chrX_164458611_164458785	0.38	Gm15211	predicted gene 15211	4518	0.2
chr2_173173528_173173681	0.38	Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	20522	0.15
chr9_65308324_65308479	0.38	Clpx	caseinolytic mitochondrial matrix peptidase chaperone subunit	1751	0.2
chr4_115597096_115597440	0.37	Cyp4a32	cytochrome P450, family 4, subfamily a, polypeptide 32	3701	0.15
chr5_66144764_66145044	0.37	Rbm47	RNA binding motif protein 47	6052	0.12
chr2_145855907_145856101	0.37	Rin2	Ras and Rab interactor 2	6640	0.18
chr9_26993230_26993422	0.37	Acad8	acyl-Coenzyme A dehydrogenase family, member 8	2273	0.21
chr19_57167572_57167907	0.37	Ablim1	actin-binding LIM protein 1	14569	0.25
chr11_75291251_75291649	0.37	Gm47300	predicted gene, 47300	27158	0.12
chr13_93629048_93629199	0.37	Gm15622	predicted gene 15622	3741	0.19
chr11_86977739_86978000	0.37	Ypel2	yippee like 2	5845	0.19
chrX_139089884_139090056	0.37	4930513O06Rik	RIKEN cDNA 4930513O06 gene	3727	0.24
chr1_72827270_72827421	0.37	Igfbp2	insulin-like growth factor binding protein 2	2023	0.37
chr16_21646037_21646193	0.36	Vps8	VPS8 CORVET complex subunit	18484	0.2
chr15_67023830_67023981	0.36	Gm31342	predicted gene, 31342	16153	0.2
chr11_78117521_78117672	0.36	Fam222b	family with sequence similarity 222, member B	1990	0.15
chr18_23805749_23805916	0.36	Mapre2	microtubule-associated protein, RP/EB family, member 2	1729	0.33
chr4_144980895_144981087	0.36	Vps13d	vacuolar protein sorting 13D	2970	0.28
chr16_22683871_22684054	0.36	Gm8118	predicted gene 8118	2232	0.29
chr19_47317600_47317752	0.36	Sh3pxd2a	SH3 and PX domains 2A	2925	0.24
chr8_36723231_36723557	0.36	Dlc1	deleted in liver cancer 1	9660	0.29
chr17_9033629_9033816	0.36	1700010I14Rik	RIKEN cDNA 1700010I14 gene	45339	0.15
chr5_65621209_65621360	0.36	Pds5a	PDS5 cohesin associated factor A	684	0.49
chr10_61440496_61440798	0.36	Gm48086	predicted gene, 48086	10070	0.1
chr17_29431614_29431765	0.36	Gm36199	predicted gene, 36199	1146	0.35
chr11_49088297_49088883	0.36	Gm12188	predicted gene 12188	47	0.79
chr1_72726316_72726507	0.36	Rpl37a	ribosomal protein L37a	14630	0.15
chr15_67062566_67062733	0.36	Gm31342	predicted gene, 31342	22591	0.2
chr17_9663030_9663198	0.36	Pabpc6	poly(A) binding protein, cytoplasmic 6	6603	0.26
chr15_3498119_3498275	0.36	Ghr	growth hormone receptor	26553	0.24
chr12_111454567_111454858	0.35	Tnfaip2	tumor necrosis factor, alpha-induced protein 2	4193	0.14
chr5_145977613_145977764	0.35	Gm43115	predicted gene 43115	9278	0.13
chr1_72828894_72829045	0.35	Igfbp2	insulin-like growth factor binding protein 2	3647	0.27
chr4_144895225_144895561	0.35	Dhrs3	dehydrogenase/reductase (SDR family) member 3	2174	0.34
chr8_10899350_10899661	0.35	4833411C07Rik	RIKEN cDNA 4833411C07 gene	417	0.64
chr7_71311560_71311861	0.35	Gm45066	predicted gene 45066	19783	0.16
chr10_18072976_18073270	0.34	Reps1	RalBP1 associated Eps domain containing protein	17119	0.19
chr10_8086797_8087175	0.34	Gm48614	predicted gene, 48614	65694	0.11
chr15_41232850_41233023	0.34	Gm49529	predicted gene, 49529	10222	0.28
chr11_95350469_95350629	0.34	Fam117a	family with sequence similarity 117, member A	10587	0.12
chr2_38379337_38379528	0.34	Gm13584	predicted gene 13584	15452	0.14
chr11_3404843_3404996	0.34	Limk2	LIM motif-containing protein kinase 2	4255	0.14
chr4_107002621_107002790	0.34	Gm12786	predicted gene 12786	19794	0.15
chr6_4927171_4927352	0.34	Gm26814	predicted gene, 26814	14886	0.13
chr1_171228435_171228593	0.34	Apoa2	apolipoprotein A-II	3423	0.09
chr9_78027220_78027380	0.34	Gm47829	predicted gene, 47829	645	0.57
chr18_20974383_20974578	0.34	Rnf125	ring finger protein 125	13008	0.2
chr11_50087465_50087659	0.34	Rnf130	ring finger protein 130	6112	0.15
chr7_39358524_39358687	0.33	Gm9271	predicted gene 9271	7793	0.16
chr13_49198886_49199037	0.33	Card19	caspase recruitment domain family, member 19	5155	0.19
chr2_167559600_167559755	0.33	Gm11476	predicted gene 11476	6363	0.13
chr14_76875854_76876258	0.33	Gm48969	predicted gene, 48969	14485	0.21
chr7_29271214_29271369	0.33	Spint2	serine protease inhibitor, Kunitz type 2	6101	0.1
chr11_109817537_109817705	0.33	1700012B07Rik	RIKEN cDNA 1700012B07 gene	3547	0.21
chr11_98750923_98751087	0.32	Thra	thyroid hormone receptor alpha	2581	0.15
chr5_135233586_135233737	0.32	Baz1b	bromodomain adjacent to zinc finger domain, 1B	8728	0.12
chr16_15890915_15891119	0.32	Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	2601	0.27
chr5_146115373_146115524	0.32	Cyp3a59	cytochrome P450, family 3, subfamily a, polypeptide 59	36181	0.09
chr8_12779654_12779811	0.32	Atp11a	ATPase, class VI, type 11A	22663	0.14
chr11_72309248_72309399	0.32	Fbxo39	F-box protein 39	5121	0.13
chr15_60911513_60911694	0.32	4930402D18Rik	RIKEN cDNA 4930402D18 gene	1371	0.4
chr4_55408726_55408877	0.32	Gm12513	predicted gene 12513	506	0.73
chr6_90756323_90756474	0.32	Iqsec1	IQ motif and Sec7 domain 1	1152	0.48
chr4_55249775_55249998	0.32	Gm12508	predicted gene 12508	4854	0.19
chr11_22804223_22804377	0.32	Gm12058	predicted gene 12058	17053	0.12
chr6_97320890_97321051	0.31	Frmd4b	FERM domain containing 4B	3170	0.3
chr4_99178772_99179088	0.31	Atg4c	autophagy related 4C, cysteine peptidase	15004	0.16
chr5_120514188_120514356	0.31	Slc8b1	solute carrier family 8 (sodium/lithium/calcium exchanger), member B1	1129	0.34
chr15_67423761_67424241	0.31	1700012I11Rik	RIKEN cDNA 1700012I11 gene	197232	0.03
chr11_112779929_112780096	0.31	BC006965	cDNA sequence BC006965	1964	0.28
chr2_3657810_3658181	0.31	Gm13183	predicted gene 13183	22595	0.15
chr15_66742693_66742844	0.31	Gm17140	predicted gene 17140	1559	0.4
chr1_67194458_67194637	0.31	Gm15668	predicted gene 15668	54653	0.12
chr1_181008197_181008537	0.31	Ephx1	epoxide hydrolase 1, microsomal	9202	0.09
chr8_11149308_11149679	0.31	Gm44717	predicted gene 44717	247	0.91
chr6_116128576_116129001	0.31	Tmcc1	transmembrane and coiled coil domains 1	5115	0.17
chr2_151943059_151943241	0.30	Gm14154	predicted gene 14154	7491	0.14
chr19_36731711_36732011	0.30	Ppp1r3c	protein phosphatase 1, regulatory subunit 3C	4792	0.24
chr4_86844668_86844856	0.30	Rps6	ribosomal protein S6	12570	0.18
chr11_88897701_88897852	0.30	Gm23507	predicted gene, 23507	7345	0.13
chr16_8581750_8581949	0.30	Abat	4-aminobutyrate aminotransferase	1778	0.28
chr19_12488282_12488454	0.30	Dtx4	deltex 4, E3 ubiquitin ligase	13086	0.1
chr6_47533521_47533999	0.30	Ezh2	enhancer of zeste 2 polycomb repressive complex 2 subunit	1365	0.42
chr13_28416267_28416437	0.30	Gm40841	predicted gene, 40841	3511	0.31
chr8_117344375_117344531	0.30	Cmip	c-Maf inducing protein	4717	0.29
chr7_113219820_113219971	0.30	Arntl	aryl hydrocarbon receptor nuclear translocator-like	12338	0.21
chr8_126838870_126839021	0.30	A630001O12Rik	RIKEN cDNA A630001O12 gene	288	0.92
chr15_25647828_25647998	0.30	Gm48996	predicted gene, 48996	13286	0.18
chr2_69401026_69401177	0.30	Dhrs9	dehydrogenase/reductase (SDR family) member 9	20656	0.19
chr12_8003138_8004354	0.30	Apob	apolipoprotein B	8613	0.24
chr10_47642098_47642249	0.30	Gm47571	predicted gene, 47571	2050	0.49
chr8_21810141_21810292	0.30	Gm15316	predicted gene 15316	7168	0.1
chr15_55252499_55252656	0.30	Gm26296	predicted gene, 26296	10026	0.23
chr10_19990685_19990873	0.30	Map3k5	mitogen-activated protein kinase kinase kinase 5	39724	0.16
chr9_78501386_78501557	0.29	Eef1a1	eukaryotic translation elongation factor 1 alpha 1	12320	0.11
chr11_21398793_21399367	0.29	Ugp2	UDP-glucose pyrophosphorylase 2	27879	0.12
chr1_182412889_182413225	0.29	Trp53bp2	transformation related protein 53 binding protein 2	3885	0.17
chr14_101771874_101772042	0.29	Lmo7	LIM domain only 7	42001	0.13
chrX_42112143_42112724	0.29	Gm14615	predicted gene 14615	18290	0.16
chr5_72366169_72366592	0.29	Corin	corin, serine peptidase	5681	0.18
chr11_74895444_74895692	0.29	Sgsm2	small G protein signaling modulator 2	1492	0.22
chr3_65527351_65527507	0.29	4931440P22Rik	RIKEN cDNA 4931440P22 gene	755	0.39
chr13_70831157_70831325	0.29	Gm36529	predicted gene, 36529	9210	0.2
chr14_30579376_30579527	0.29	Mir3076	microRNA 3076	7302	0.14
chr15_34493251_34493646	0.29	Rida	reactive intermediate imine deaminase A homolog	1723	0.21
chr5_134440233_134440384	0.29	Gm26340	predicted gene, 26340	8266	0.11
chr14_103099863_103100150	0.29	Fbxl3	F-box and leucine-rich repeat protein 3	440	0.8
chr11_81488827_81488995	0.29	1700071K01Rik	RIKEN cDNA 1700071K01 gene	84562	0.09
chr7_139416534_139416685	0.29	Inpp5a	inositol polyphosphate-5-phosphatase A	16120	0.23
chr8_4335762_4335913	0.29	Ccl25	chemokine (C-C motif) ligand 25	3578	0.14
chr1_13103635_13103786	0.29	Prdm14	PR domain containing 14	23453	0.13
chr19_23032874_23033121	0.29	Gm50136	predicted gene, 50136	28457	0.18
chr14_93075636_93076058	0.28	Gm23509	predicted gene, 23509	62342	0.14
chr9_61422608_61422759	0.28	Tle3	transducin-like enhancer of split 3	12746	0.17
chr10_3920682_3920833	0.28	Gm23023	predicted gene, 23023	14120	0.15
chr6_133960296_133960447	0.28	Gm8956	predicted gene 8956	27962	0.17
chr15_82147771_82148080	0.28	Srebf2	sterol regulatory element binding factor 2	88	0.94
chr12_110381296_110381622	0.28	Gm47195	predicted gene, 47195	56074	0.08
chr13_32405059_32405228	0.28	Gm11381	predicted gene 11381	21455	0.21
chr4_140636700_140636879	0.28	Arhgef10l	Rho guanine nucleotide exchange factor (GEF) 10-like	11961	0.16
chr6_8416975_8417147	0.28	Umad1	UMAP1-MVP12 associated (UMA) domain containing 1	2617	0.24
chr14_22269831_22270192	0.28	Lrmda	leucine rich melanocyte differentiation associated	40154	0.2
chr7_135609185_135609546	0.28	Ptpre	protein tyrosine phosphatase, receptor type, E	3537	0.23
chr11_100836746_100836921	0.28	Stat5b	signal transducer and activator of transcription 5B	13705	0.12
chr3_81061801_81061984	0.28	Gm16000	predicted gene 16000	21455	0.16
chr6_121878156_121878361	0.28	Mug1	murinoglobulin 1	7319	0.2
chr8_10857392_10857567	0.28	Gm32540	predicted gene, 32540	8707	0.12

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc3

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0046439	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.2	0.5	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.2	0.5	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.1	0.6	GO:0009115	xanthine catabolic process(GO:0009115)
0.1	0.5	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1	0.9	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.1	0.3	GO:0015766	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1	0.5	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.3	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1	0.3	GO:0038161	prolactin signaling pathway(GO:0038161)
0.1	0.2	GO:0001543	ovarian follicle rupture(GO:0001543)
0.1	0.2	GO:0045472	response to ether(GO:0045472)
0.1	0.2	GO:0006203	dGTP catabolic process(GO:0006203)
0.1	0.2	GO:0030242	pexophagy(GO:0030242)
0.1	0.2	GO:0018992	germ-line sex determination(GO:0018992)
0.1	0.3	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.1	0.3	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.1	0.3	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.1	0.2	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.1	0.8	GO:0006577	amino-acid betaine metabolic process(GO:0006577)
0.1	0.2	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1	0.2	GO:0032763	regulation of mast cell cytokine production(GO:0032763)
0.1	0.5	GO:0006991	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1	0.1	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.1	0.4	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.3	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.1	0.3	GO:2001171	positive regulation of ATP biosynthetic process(GO:2001171)
0.1	0.1	GO:0045608	negative regulation of auditory receptor cell differentiation(GO:0045608)
0.1	0.2	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1	0.3	GO:0072675	osteoclast fusion(GO:0072675)
0.1	0.2	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.1	GO:1904754	positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
0.1	0.2	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1	0.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.2	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.0	0.1	GO:0010909	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0	0.1	GO:1904217	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:0003162	atrioventricular node development(GO:0003162)
0.0	0.1	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.2	GO:0032348	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0	0.2	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.0	0.2	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.0	0.2	GO:0072015	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0	0.2	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0071332	cellular response to fructose stimulus(GO:0071332)
0.0	0.0	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.0	0.1	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0	0.2	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.0	0.3	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	0.1	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.0	0.1	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0	0.2	GO:0060332	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.2	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.0	0.2	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.1	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0	0.2	GO:1902548	negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.0	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.1	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.3	GO:0051775	response to redox state(GO:0051775)
0.0	0.1	GO:0033566	gamma-tubulin complex localization(GO:0033566)
0.0	0.1	GO:1903626	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0	0.1	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.0	0.1	GO:0044838	cell quiescence(GO:0044838)
0.0	0.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.1	GO:0070889	platelet alpha granule organization(GO:0070889)
0.0	0.1	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.0	0.1	GO:0016095	polyprenol catabolic process(GO:0016095)
0.0	0.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0034443	negative regulation of lipoprotein oxidation(GO:0034443)
0.0	0.2	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	0.2	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.1	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.2	GO:0030913	paranodal junction assembly(GO:0030913)
0.0	0.3	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.1	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0	0.1	GO:0065001	specification of axis polarity(GO:0065001)
0.0	0.1	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.2	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.0	0.1	GO:2000667	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0	0.0	GO:0015744	succinate transport(GO:0015744)
0.0	0.3	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	0.2	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.1	GO:0002740	negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0	0.0	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.0	0.1	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.2	GO:0002488	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.0	0.1	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.1	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.0	0.0	GO:1903660	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.2	GO:0034144	negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0	0.1	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.9	GO:0006213	pyrimidine nucleoside metabolic process(GO:0006213)
0.0	0.1	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	0.1	GO:0006113	fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.1	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.1	GO:0072095	regulation of branch elongation involved in ureteric bud branching(GO:0072095)
0.0	0.1	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.0	0.1	GO:0070587	negative regulation of heterotypic cell-cell adhesion(GO:0034115) regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.0	0.0	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.2	GO:0090232	positive regulation of spindle checkpoint(GO:0090232)
0.0	0.2	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.1	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.2	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.1	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.0	0.1	GO:0036394	amylase secretion(GO:0036394)
0.0	0.2	GO:0019401	alditol biosynthetic process(GO:0019401)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.3	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.2	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.2	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.2	GO:0043312	neutrophil degranulation(GO:0043312)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.1	GO:0031508	pericentric heterochromatin assembly(GO:0031508)
0.0	0.1	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.0	0.1	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.1	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.1	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.1	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.1	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.1	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
0.0	0.2	GO:1902033	regulation of hematopoietic stem cell proliferation(GO:1902033)
0.0	0.1	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	0.1	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.0	0.1	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.1	GO:0035513	oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0	0.1	GO:0008050	female courtship behavior(GO:0008050)
0.0	0.6	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.1	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.2	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0046077	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.0	0.2	GO:0071361	cellular response to ethanol(GO:0071361)
0.0	0.0	GO:0006183	GTP biosynthetic process(GO:0006183)
0.0	0.3	GO:0051601	exocyst localization(GO:0051601)
0.0	0.1	GO:0002309	T cell proliferation involved in immune response(GO:0002309)
0.0	0.3	GO:0006544	glycine metabolic process(GO:0006544)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.5	GO:0061436	establishment of skin barrier(GO:0061436)
0.0	0.1	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0	0.1	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0	0.3	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.1	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.2	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.0	0.1	GO:0034372	very-low-density lipoprotein particle remodeling(GO:0034372)
0.0	0.1	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.1	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.1	GO:1902534	single-organism membrane invagination(GO:1902534)
0.0	0.1	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0	0.1	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.0	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	0.1	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.2	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.0	GO:0061687	detoxification of copper ion(GO:0010273) detoxification of inorganic compound(GO:0061687) stress response to copper ion(GO:1990169)
0.0	0.1	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0	0.1	GO:1903887	motile primary cilium assembly(GO:1903887)
0.0	0.0	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0	0.0	GO:0002432	granuloma formation(GO:0002432)
0.0	0.2	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.0	0.2	GO:0006662	glycerol ether metabolic process(GO:0006662)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.0	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.0	0.1	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.1	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0	0.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.1	GO:1904936	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0	0.1	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.0	0.0	GO:0006901	vesicle coating(GO:0006901)
0.0	0.0	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0	0.1	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0	0.1	GO:1902093	positive regulation of sperm motility(GO:1902093)
0.0	0.1	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0	0.1	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.1	GO:1901679	pyrimidine-containing compound transmembrane transport(GO:0072531) nucleotide transmembrane transport(GO:1901679)
0.0	0.0	GO:1990791	dorsal root ganglion development(GO:1990791)
0.0	0.1	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.0	0.1	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.1	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0	0.2	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0	0.2	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.1	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.1	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.1	GO:0044539	long-chain fatty acid import(GO:0044539)
0.0	0.0	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0	0.1	GO:0032484	Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0	0.2	GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0	0.2	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.1	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.1	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0	0.0	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0	0.1	GO:0016139	glycoside catabolic process(GO:0016139)
0.0	0.1	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.0	0.1	GO:0042559	pteridine-containing compound biosynthetic process(GO:0042559)
0.0	0.1	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.0	GO:0052200	response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.0	GO:1904430	negative regulation of t-circle formation(GO:1904430)
0.0	0.1	GO:0021593	rhombomere morphogenesis(GO:0021593)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.2	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.1	GO:0060018	astrocyte fate commitment(GO:0060018)
0.0	0.1	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.0	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.0	0.1	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.4	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.1	GO:0040031	snRNA modification(GO:0040031)
0.0	0.0	GO:0002930	trabecular meshwork development(GO:0002930)
0.0	0.1	GO:0051031	tRNA transport(GO:0051031)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.0	GO:0018904	ether metabolic process(GO:0018904)
0.0	0.1	GO:0016102	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.0	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0	0.0	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.0	0.1	GO:0010825	positive regulation of centrosome duplication(GO:0010825)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0	0.1	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.0	0.1	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.1	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.0	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.1	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.0	0.2	GO:0030575	nuclear body organization(GO:0030575)
0.0	0.1	GO:0030070	insulin processing(GO:0030070)
0.0	0.0	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.1	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.0	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.1	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.0	0.1	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.0	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.0	GO:2000041	regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.0	0.1	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.1	GO:0018202	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0	0.1	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.0	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.0	0.0	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0	0.0	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0	0.1	GO:0097421	liver regeneration(GO:0097421)
0.0	0.3	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.1	GO:0060051	negative regulation of protein glycosylation(GO:0060051)
0.0	0.0	GO:0060847	endothelial cell fate specification(GO:0060847)
0.0	0.1	GO:0098535	de novo centriole assembly(GO:0098535)
0.0	0.0	GO:0036258	multivesicular body assembly(GO:0036258)
0.0	0.0	GO:0033023	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.0	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0	0.0	GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0	0.1	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.0	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282)
0.0	0.1	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.0	0.1	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.0	0.0	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.1	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.3	GO:0046470	phosphatidylcholine metabolic process(GO:0046470)
0.0	0.1	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.0	0.1	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
0.0	0.1	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	0.1	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
0.0	0.1	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112)
0.0	0.0	GO:0045918	negative regulation of cytolysis(GO:0045918)
0.0	0.5	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.2	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0002525	acute inflammatory response to non-antigenic stimulus(GO:0002525)
0.0	0.0	GO:0051799	negative regulation of hair follicle development(GO:0051799)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.0	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
0.0	0.0	GO:0019086	late viral transcription(GO:0019086)
0.0	0.0	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0	0.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.0	GO:0090310	negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0	0.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.0	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.0	GO:1902430	negative regulation of beta-amyloid formation(GO:1902430)
0.0	0.1	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.0	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
0.0	0.1	GO:0007288	sperm axoneme assembly(GO:0007288)
0.0	0.1	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.0	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.0	GO:0035290	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0	0.0	GO:0021648	vestibulocochlear nerve morphogenesis(GO:0021648)
0.0	0.1	GO:0043102	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.0	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.0	GO:0015817	histidine transport(GO:0015817)
0.0	0.2	GO:0030497	fatty acid elongation(GO:0030497)
0.0	0.0	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.1	GO:1900118	negative regulation of execution phase of apoptosis(GO:1900118)
0.0	0.1	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.0	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0	0.0	GO:1901856	negative regulation of cellular respiration(GO:1901856)
0.0	0.0	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.0	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.0	0.1	GO:0002082	regulation of oxidative phosphorylation(GO:0002082)
0.0	0.0	GO:0009240	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.1	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0	0.0	GO:0051661	maintenance of centrosome location(GO:0051661)
0.0	0.0	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.0	0.3	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:1902895	positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0	0.1	GO:0021764	amygdala development(GO:0021764)
0.0	0.1	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.0	GO:0071677	positive regulation of mononuclear cell migration(GO:0071677)
0.0	0.1	GO:0009992	cellular water homeostasis(GO:0009992)
0.0	0.0	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
0.0	0.0	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.1	GO:0003097	renal water transport(GO:0003097)
0.0	0.1	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.0	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015)
0.0	0.1	GO:0035630	bone mineralization involved in bone maturation(GO:0035630)
0.0	0.2	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.1	GO:0070234	positive regulation of T cell apoptotic process(GO:0070234)
0.0	0.0	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.1	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.1	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.0	GO:0046066	purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.0	0.0	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.0	0.0	GO:0061110	dense core granule biogenesis(GO:0061110)
0.0	0.0	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.2	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.0	0.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.0	GO:0070627	ferrous iron import(GO:0070627) ferrous iron import into cell(GO:0097460)
0.0	0.1	GO:0070431	nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0	0.0	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.0	GO:0071107	response to parathyroid hormone(GO:0071107)
0.0	0.0	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0	0.0	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.0	0.1	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.1	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0	0.1	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	0.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.1	GO:0042701	progesterone secretion(GO:0042701)
0.0	0.1	GO:1900121	negative regulation of receptor binding(GO:1900121)
0.0	0.1	GO:0014041	regulation of neuron maturation(GO:0014041)
0.0	0.0	GO:0038094	Fc-gamma receptor signaling pathway(GO:0038094)
0.0	0.0	GO:1904995	negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.0	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.0	0.1	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.1	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
0.0	0.1	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.1	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.1	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.0	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
0.0	0.0	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.0	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.0	GO:1904415	regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.0	0.2	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.0	GO:0043309	regulation of eosinophil degranulation(GO:0043309)
0.0	0.0	GO:1901529	positive regulation of anion channel activity(GO:1901529)
0.0	0.0	GO:0044375	regulation of peroxisome size(GO:0044375)
0.0	0.0	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0	0.0	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.1	GO:0042635	positive regulation of hair cycle(GO:0042635)
0.0	0.0	GO:0002835	negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.0	0.0	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.0	GO:0003347	epicardial cell to mesenchymal cell transition(GO:0003347)
0.0	0.1	GO:0031017	exocrine pancreas development(GO:0031017)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.0	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0048241	epinephrine transport(GO:0048241)
0.0	0.0	GO:0061511	centriole elongation(GO:0061511)
0.0	0.3	GO:0030318	melanocyte differentiation(GO:0030318)
0.0	0.1	GO:1904816	positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0	0.1	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.1	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.2	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.0	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.0	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.0	0.0	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.0	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.0	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.0	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.0	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.0	0.0	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.0	0.1	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0	0.0	GO:0046645	positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0	0.0	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.0	0.0	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.0	GO:0072053	renal inner medulla development(GO:0072053)
0.0	0.1	GO:1904353	regulation of telomere capping(GO:1904353)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.0	GO:0043302	positive regulation of leukocyte degranulation(GO:0043302)
0.0	0.1	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.0	0.0	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.0	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.0	GO:0043545	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.0	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.0	0.0	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.0	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.0	0.1	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.1	GO:0002035	brain renin-angiotensin system(GO:0002035)
0.0	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.0	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.0	GO:0071725	response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0	0.2	GO:0060337	type I interferon signaling pathway(GO:0060337)
0.0	0.0	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0	0.0	GO:0030222	eosinophil differentiation(GO:0030222)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0014733	regulation of skeletal muscle adaptation(GO:0014733)
0.0	0.0	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0	0.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.0	GO:2000313	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0	0.0	GO:0006772	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0	0.0	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.0	0.0	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.0	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.0	GO:0002572	pro-T cell differentiation(GO:0002572)
0.0	0.1	GO:1903867	chorion development(GO:0060717) extraembryonic membrane development(GO:1903867)
0.0	0.0	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.0	GO:0002434	immune complex clearance(GO:0002434)
0.0	0.0	GO:1902992	negative regulation of amyloid precursor protein catabolic process(GO:1902992)
0.0	0.0	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.0	GO:0060375	regulation of mast cell differentiation(GO:0060375)
0.0	0.0	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.2	0.6	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.1	0.7	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.4	GO:0044462	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.1	0.2	GO:0031084	BLOC-2 complex(GO:0031084)
0.1	0.1	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.1	0.2	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.1	0.1	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.1	0.2	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.2	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.3	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.4	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.3	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.1	GO:0000811	GINS complex(GO:0000811)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.2	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.1	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.1	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0097255	R2TP complex(GO:0097255)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0044326	dendritic spine neck(GO:0044326)
0.0	0.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.1	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.3	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.2	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.1	GO:0035363	histone locus body(GO:0035363)
0.0	0.2	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.3	GO:0038201	TOR complex(GO:0038201)
0.0	0.1	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.1	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.1	GO:0042583	chromaffin granule(GO:0042583)
0.0	0.1	GO:0097512	cardiac myofibril(GO:0097512)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.1	GO:0098536	deuterosome(GO:0098536)
0.0	0.1	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.1	GO:1990246	uniplex complex(GO:1990246)
0.0	0.3	GO:0001741	XY body(GO:0001741)
0.0	0.3	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.0	GO:0032010	phagolysosome(GO:0032010)
0.0	0.1	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.1	GO:0033061	DNA recombinase mediator complex(GO:0033061)
0.0	0.2	GO:0031231	intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.0	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.3	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.3	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0000938	GARP complex(GO:0000938)
0.0	0.1	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0043203	axon hillock(GO:0043203)
0.0	0.0	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.0	GO:0097454	Schwann cell microvillus(GO:0097454)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.0	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.0	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.0	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.2	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.2	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.0	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.2	GO:0036038	MKS complex(GO:0036038)
0.0	0.0	GO:1990923	PET complex(GO:1990923)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.0	GO:0035838	growing cell tip(GO:0035838)
0.0	0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.0	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.2	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.2	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.0	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.1	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.1	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.0	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)
0.0	0.0	GO:0071953	elastic fiber(GO:0071953)
0.0	0.1	GO:1990023	mitotic spindle midzone(GO:1990023)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.7	GO:0004645	phosphorylase activity(GO:0004645)
0.1	0.6	GO:0016726	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.1	0.4	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1	0.6	GO:0035473	lipase binding(GO:0035473)
0.1	0.3	GO:0015154	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1	0.6	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1	0.5	GO:0050051	leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.1	0.7	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.2	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1	0.5	GO:0034560	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.1	0.3	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.2	GO:0019776	Atg8 ligase activity(GO:0019776)
0.1	0.2	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.1	0.2	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.1	0.2	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.4	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.1	0.2	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	0.2	GO:0042895	antibiotic transporter activity(GO:0042895)
0.1	0.2	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.1	GO:0019961	interferon binding(GO:0019961)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.2	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0	0.1	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.2	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.2	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.2	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.2	GO:0008390	testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.0	0.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.3	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.3	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.0	GO:0015141	succinate transmembrane transporter activity(GO:0015141)
0.0	0.0	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.1	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.1	GO:0018741	alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0	0.3	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0	0.1	GO:0047751	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0	0.1	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0	0.1	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	0.2	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.0	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.2	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.2	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0019959	interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.3	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0030984	kininogen binding(GO:0030984)
0.0	0.1	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.1	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.2	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.4	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.4	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.0	GO:0009041	uridylate kinase activity(GO:0009041)
0.0	0.1	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.0	GO:0070698	type I activin receptor binding(GO:0070698)
0.0	0.1	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0	0.1	GO:0042731	PH domain binding(GO:0042731)
0.0	0.1	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.0	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.0	0.0	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0	0.1	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.1	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.0	0.1	GO:0052759	4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.3	GO:0015299	solute:proton antiporter activity(GO:0015299)
0.0	0.3	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.1	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.0	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.1	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0032554	purine deoxyribonucleotide binding(GO:0032554)
0.0	0.1	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0	0.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.0	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.0	0.5	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0	0.1	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.4	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.2	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.2	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.2	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.0	GO:0005415	nucleoside:sodium symporter activity(GO:0005415)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.5	GO:0016414	O-octanoyltransferase activity(GO:0016414)
0.0	0.3	GO:0008483	transaminase activity(GO:0008483)
0.0	0.1	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.1	GO:0031432	titin binding(GO:0031432)
0.0	0.0	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.0	0.1	GO:0102345	3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0	0.1	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.0	GO:0005290	L-histidine transmembrane transporter activity(GO:0005290)
0.0	0.3	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0018585	fluorene oxygenase activity(GO:0018585)
0.0	0.2	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.0	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.0	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.0	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
0.0	0.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.3	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.0	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0016803	ether hydrolase activity(GO:0016803)
0.0	0.2	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.0	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
0.0	0.0	GO:0042910	xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.0	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.0	0.0	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.1	GO:0045340	mercury ion binding(GO:0045340)
0.0	0.0	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.2	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.0	GO:0019767	IgE receptor activity(GO:0019767)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.0	GO:0005350	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.1	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.0	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0005542	folic acid binding(GO:0005542)
0.0	0.1	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.2	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.1	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.0	GO:0023029	MHC class Ib protein binding(GO:0023029)
0.0	0.3	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	0.1	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.0	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.0	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0	0.0	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	0.0	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.0	0.0	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0	0.0	GO:0071209	U7 snRNA binding(GO:0071209)
0.0	0.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.0	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.0	0.0	GO:0005329	dopamine transmembrane transporter activity(GO:0005329)
0.0	0.0	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.0	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.0	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.0	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.0	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.1	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.0	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0	0.0	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0	0.0	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.1	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.0	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.3	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.1	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0	0.0	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.0	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.1	GO:0015298	solute:cation antiporter activity(GO:0015298)
0.0	0.0	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.0	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	0.0	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.0	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.0	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.0	0.2	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.0	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0	0.0	GO:0070878	primary miRNA binding(GO:0070878)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.2	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.1	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	1.0	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.8	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.8	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.2	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.0	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.2	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.2	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.8	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.4	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.1	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.0	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.3	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.1	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.0	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.0	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.2	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.2	PID MYC PATHWAY	C-MYC pathway
0.0	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.1	PID ERBB4 PATHWAY	ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	0.8	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1	0.8	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.9	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.0	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.7	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.1	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.2	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.1	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.1	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.1	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.2	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.0	0.2	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.0	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.4	REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.3	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.0	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.2	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.5	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.0	0.0	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.1	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.0	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.2	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates

Results for Nfatc3

Z-value: 1.28

Motif logo

Transcription factors associated with Nfatc3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Nfatc3 motif across conditions

Conditions sorted by the z-value of the Nfatc3 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: