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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Nfatc3

Z-value: 1.28

Motif logo

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Transcription factors associated with Nfatc3

Gene Symbol Gene ID Gene Info
ENSMUSG00000031902.9 Nfatc3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

GenePromoterDistanceAssociation probabilityPearson corr. coef.P-valuePlot
Nfatc3chr8_106060353_1060605047950.476272-0.777.4e-02Click!
Nfatc3chr8_106059327_1060595092150.8839950.621.9e-01Click!
Nfatc3chr8_106074066_106074226145130.1052360.572.4e-01Click!
Nfatc3chr8_106059647_1060603413610.7779770.443.8e-01Click!
Nfatc3chr8_106069760_106069911102020.109261-0.355.0e-01Click!

Activity of the Nfatc3 motif across conditions

Conditions sorted by the z-value of the Nfatc3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_46140539_46140690 1.05 Pitx3
paired-like homeodomain transcription factor 3
369
0.79
chr18_46720026_46720377 0.98 Cdo1
cysteine dioxygenase 1, cytosolic
7828
0.13
chr4_144956318_144956685 0.96 Gm38074
predicted gene, 38074
2347
0.3
chr9_43225133_43225294 0.94 Oaf
out at first homolog
121
0.95
chr19_42601924_42602199 0.80 Loxl4
lysyl oxidase-like 4
1260
0.45
chr13_93625401_93625555 0.80 Gm15622
predicted gene 15622
96
0.96
chr10_8089089_8089240 0.80 Gm48614
predicted gene, 48614
67872
0.11
chr15_89377019_89377232 0.76 Tymp
thymidine phosphorylase
86
0.89
chr1_72145974_72146125 0.67 Gm4319
predicted gene 4319
24048
0.15
chr2_153656760_153657071 0.64 Dnmt3bos
DNA methyltransferase 3B, opposite strand
6629
0.16
chr3_83006212_83006467 0.64 Fgg
fibrinogen gamma chain
1385
0.32
chr2_33274814_33274965 0.64 Gm13537
predicted gene 13537
48282
0.11
chr16_76242740_76242921 0.63 Nrip1
nuclear receptor interacting protein 1
80828
0.08
chr11_75211079_75211230 0.60 Rtn4rl1
reticulon 4 receptor-like 1
17371
0.1
chr15_97019476_97019938 0.58 Slc38a4
solute carrier family 38, member 4
244
0.95
chr19_42610535_42610705 0.58 Loxl4
lysyl oxidase-like 4
2089
0.31
chr19_42891636_42891940 0.58 Hps1
HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
111810
0.06
chr1_133257148_133257349 0.55 Gm19461
predicted gene, 19461
130
0.89
chr3_37934934_37935257 0.54 Gm7799
predicted gene 7799
24992
0.14
chr12_52442391_52442588 0.53 Gm47431
predicted gene, 47431
5636
0.23
chr9_43467603_43467754 0.53 Gm28215
predicted gene 28215
1744
0.35
chr7_87222899_87223055 0.51 Gm6230
predicted gene 6230
19908
0.21
chr1_131969813_131969968 0.50 Slc45a3
solute carrier family 45, member 3
719
0.55
chr3_132917768_132917922 0.50 Npnt
nephronectin
11486
0.16
chr10_121428648_121428803 0.49 Gm18730
predicted gene, 18730
28012
0.1
chr12_80107632_80107989 0.49 Zfp36l1
zinc finger protein 36, C3H type-like 1
5184
0.14
chr9_65288876_65289027 0.49 Clpx
caseinolytic mitochondrial matrix peptidase chaperone subunit
5309
0.12
chr5_64712724_64712894 0.49 Gm20033
predicted gene, 20033
1640
0.32
chr8_105820252_105820414 0.49 Ranbp10
RAN binding protein 10
6872
0.09
chr2_103844031_103844275 0.49 Gm13879
predicted gene 13879
497
0.45
chr17_29496086_29496540 0.49 Pim1
proviral integration site 1
2906
0.15
chr5_105112436_105112587 0.48 Gbp9
guanylate-binding protein 9
2234
0.28
chr8_35417280_35417458 0.47 Gm45301
predicted gene 45301
7863
0.17
chr12_109988784_109988986 0.47 Gm34667
predicted gene, 34667
34988
0.09
chr12_21143230_21143533 0.47 Asap2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
31427
0.16
chr8_10968601_10968792 0.47 Gm44956
predicted gene 44956
2118
0.2
chr5_8962552_8962757 0.46 Abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
4102
0.15
chr10_68355501_68355861 0.46 4930545H06Rik
RIKEN cDNA 4930545H06 gene
34539
0.17
chr10_122384642_122385270 0.45 Gm36041
predicted gene, 36041
1936
0.39
chr18_75180173_75180522 0.45 Gm8807
predicted gene 8807
2467
0.32
chr4_33257682_33258147 0.45 Pnrc1
proline-rich nuclear receptor coactivator 1
9404
0.17
chr5_139872154_139872313 0.44 Gm42423
predicted gene 42423
23576
0.12
chr4_141826031_141826198 0.44 Cela2a
chymotrypsin-like elastase family, member 2A
46
0.95
chr3_118507933_118508602 0.44 Gm37773
predicted gene, 37773
17884
0.14
chr5_121858862_121859046 0.44 Cux2
cut-like homeobox 2
7109
0.11
chr13_98595769_98595925 0.43 Gm4815
predicted gene 4815
17654
0.12
chr12_4583826_4584201 0.42 Gm48610
predicted gene, 48610
7257
0.13
chr16_4029500_4029663 0.42 Dnase1
deoxyribonuclease I
7361
0.1
chr19_41449775_41450079 0.41 Gm9788
predicted pseudogene 9788
9886
0.21
chr10_95583008_95583178 0.41 Nudt4
nudix (nucleoside diphosphate linked moiety X)-type motif 4
18947
0.12
chr11_19962395_19962565 0.41 Spred2
sprouty-related EVH1 domain containing 2
7910
0.28
chr17_23675280_23675431 0.41 Tnfrsf12a
tumor necrosis factor receptor superfamily, member 12a
1198
0.16
chr6_126035696_126035896 0.41 Ntf3
neurotrophin 3
129164
0.05
chr18_20938375_20938560 0.41 Rnf125
ring finger protein 125
6158
0.22
chr16_91762844_91763094 0.41 Itsn1
intersectin 1 (SH3 domain protein 1A)
6870
0.17
chr9_21807212_21807383 0.40 Mir7083
microRNA 7083
2703
0.15
chr19_46639707_46639916 0.40 Wbp1l
WW domain binding protein 1 like
16410
0.12
chr4_44985654_44986028 0.40 Grhpr
glyoxylate reductase/hydroxypyruvate reductase
4341
0.13
chrX_166475078_166475249 0.40 Rab9
RAB9, member RAS oncogene family
272
0.87
chr2_38378853_38379004 0.39 Gm13584
predicted gene 13584
14948
0.14
chr10_63248712_63248888 0.39 Gm19337
predicted gene, 19337
2132
0.19
chr12_85748786_85748937 0.39 Flvcr2
feline leukemia virus subgroup C cellular receptor 2
2322
0.22
chr9_103064909_103065087 0.39 Gm47468
predicted gene, 47468
20528
0.14
chr7_112202260_112202451 0.39 Mical2
microtubule associated monooxygenase, calponin and LIM domain containing 2
23501
0.22
chr13_102877226_102877399 0.39 Mast4
microtubule associated serine/threonine kinase family member 4
28474
0.23
chr13_73730823_73730977 0.39 Slc12a7
solute carrier family 12, member 7
2194
0.26
chr15_10248990_10249545 0.39 Prlr
prolactin receptor
293
0.94
chr15_66951818_66951981 0.39 Ndrg1
N-myc downstream regulated gene 1
3420
0.21
chr3_69120460_69120611 0.39 Gm37558
predicted gene, 37558
2189
0.22
chr1_58475966_58476117 0.38 Orc2
origin recognition complex, subunit 2
5408
0.13
chr6_121874198_121874349 0.38 Mug1
murinoglobulin 1
11304
0.19
chr1_39192739_39192927 0.38 Npas2
neuronal PAS domain protein 2
898
0.59
chr14_70338039_70338256 0.38 Slc39a14
solute carrier family 39 (zinc transporter), member 14
3949
0.15
chrX_164458611_164458785 0.38 Gm15211
predicted gene 15211
4518
0.2
chr2_173173528_173173681 0.38 Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic
20522
0.15
chr9_65308324_65308479 0.38 Clpx
caseinolytic mitochondrial matrix peptidase chaperone subunit
1751
0.2
chr4_115597096_115597440 0.37 Cyp4a32
cytochrome P450, family 4, subfamily a, polypeptide 32
3701
0.15
chr5_66144764_66145044 0.37 Rbm47
RNA binding motif protein 47
6052
0.12
chr2_145855907_145856101 0.37 Rin2
Ras and Rab interactor 2
6640
0.18
chr9_26993230_26993422 0.37 Acad8
acyl-Coenzyme A dehydrogenase family, member 8
2273
0.21
chr19_57167572_57167907 0.37 Ablim1
actin-binding LIM protein 1
14569
0.25
chr11_75291251_75291649 0.37 Gm47300
predicted gene, 47300
27158
0.12
chr13_93629048_93629199 0.37 Gm15622
predicted gene 15622
3741
0.19
chr11_86977739_86978000 0.37 Ypel2
yippee like 2
5845
0.19
chrX_139089884_139090056 0.37 4930513O06Rik
RIKEN cDNA 4930513O06 gene
3727
0.24
chr1_72827270_72827421 0.37 Igfbp2
insulin-like growth factor binding protein 2
2023
0.37
chr16_21646037_21646193 0.36 Vps8
VPS8 CORVET complex subunit
18484
0.2
chr15_67023830_67023981 0.36 Gm31342
predicted gene, 31342
16153
0.2
chr11_78117521_78117672 0.36 Fam222b
family with sequence similarity 222, member B
1990
0.15
chr18_23805749_23805916 0.36 Mapre2
microtubule-associated protein, RP/EB family, member 2
1729
0.33
chr4_144980895_144981087 0.36 Vps13d
vacuolar protein sorting 13D
2970
0.28
chr16_22683871_22684054 0.36 Gm8118
predicted gene 8118
2232
0.29
chr19_47317600_47317752 0.36 Sh3pxd2a
SH3 and PX domains 2A
2925
0.24
chr8_36723231_36723557 0.36 Dlc1
deleted in liver cancer 1
9660
0.29
chr17_9033629_9033816 0.36 1700010I14Rik
RIKEN cDNA 1700010I14 gene
45339
0.15
chr5_65621209_65621360 0.36 Pds5a
PDS5 cohesin associated factor A
684
0.49
chr10_61440496_61440798 0.36 Gm48086
predicted gene, 48086
10070
0.1
chr17_29431614_29431765 0.36 Gm36199
predicted gene, 36199
1146
0.35
chr11_49088297_49088883 0.36 Gm12188
predicted gene 12188
47
0.79
chr1_72726316_72726507 0.36 Rpl37a
ribosomal protein L37a
14630
0.15
chr15_67062566_67062733 0.36 Gm31342
predicted gene, 31342
22591
0.2
chr17_9663030_9663198 0.36 Pabpc6
poly(A) binding protein, cytoplasmic 6
6603
0.26
chr15_3498119_3498275 0.36 Ghr
growth hormone receptor
26553
0.24
chr12_111454567_111454858 0.35 Tnfaip2
tumor necrosis factor, alpha-induced protein 2
4193
0.14
chr5_145977613_145977764 0.35 Gm43115
predicted gene 43115
9278
0.13
chr1_72828894_72829045 0.35 Igfbp2
insulin-like growth factor binding protein 2
3647
0.27
chr4_144895225_144895561 0.35 Dhrs3
dehydrogenase/reductase (SDR family) member 3
2174
0.34
chr8_10899350_10899661 0.35 4833411C07Rik
RIKEN cDNA 4833411C07 gene
417
0.64
chr7_71311560_71311861 0.35 Gm45066
predicted gene 45066
19783
0.16
chr10_18072976_18073270 0.34 Reps1
RalBP1 associated Eps domain containing protein
17119
0.19
chr10_8086797_8087175 0.34 Gm48614
predicted gene, 48614
65694
0.11
chr15_41232850_41233023 0.34 Gm49529
predicted gene, 49529
10222
0.28
chr11_95350469_95350629 0.34 Fam117a
family with sequence similarity 117, member A
10587
0.12
chr2_38379337_38379528 0.34 Gm13584
predicted gene 13584
15452
0.14
chr11_3404843_3404996 0.34 Limk2
LIM motif-containing protein kinase 2
4255
0.14
chr4_107002621_107002790 0.34 Gm12786
predicted gene 12786
19794
0.15
chr6_4927171_4927352 0.34 Gm26814
predicted gene, 26814
14886
0.13
chr1_171228435_171228593 0.34 Apoa2
apolipoprotein A-II
3423
0.09
chr9_78027220_78027380 0.34 Gm47829
predicted gene, 47829
645
0.57
chr18_20974383_20974578 0.34 Rnf125
ring finger protein 125
13008
0.2
chr11_50087465_50087659 0.34 Rnf130
ring finger protein 130
6112
0.15
chr7_39358524_39358687 0.33 Gm9271
predicted gene 9271
7793
0.16
chr13_49198886_49199037 0.33 Card19
caspase recruitment domain family, member 19
5155
0.19
chr2_167559600_167559755 0.33 Gm11476
predicted gene 11476
6363
0.13
chr14_76875854_76876258 0.33 Gm48969
predicted gene, 48969
14485
0.21
chr7_29271214_29271369 0.33 Spint2
serine protease inhibitor, Kunitz type 2
6101
0.1
chr11_109817537_109817705 0.33 1700012B07Rik
RIKEN cDNA 1700012B07 gene
3547
0.21
chr11_98750923_98751087 0.32 Thra
thyroid hormone receptor alpha
2581
0.15
chr5_135233586_135233737 0.32 Baz1b
bromodomain adjacent to zinc finger domain, 1B
8728
0.12
chr16_15890915_15891119 0.32 Cebpd
CCAAT/enhancer binding protein (C/EBP), delta
2601
0.27
chr5_146115373_146115524 0.32 Cyp3a59
cytochrome P450, family 3, subfamily a, polypeptide 59
36181
0.09
chr8_12779654_12779811 0.32 Atp11a
ATPase, class VI, type 11A
22663
0.14
chr11_72309248_72309399 0.32 Fbxo39
F-box protein 39
5121
0.13
chr15_60911513_60911694 0.32 4930402D18Rik
RIKEN cDNA 4930402D18 gene
1371
0.4
chr4_55408726_55408877 0.32 Gm12513
predicted gene 12513
506
0.73
chr6_90756323_90756474 0.32 Iqsec1
IQ motif and Sec7 domain 1
1152
0.48
chr4_55249775_55249998 0.32 Gm12508
predicted gene 12508
4854
0.19
chr11_22804223_22804377 0.32 Gm12058
predicted gene 12058
17053
0.12
chr6_97320890_97321051 0.31 Frmd4b
FERM domain containing 4B
3170
0.3
chr4_99178772_99179088 0.31 Atg4c
autophagy related 4C, cysteine peptidase
15004
0.16
chr5_120514188_120514356 0.31 Slc8b1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
1129
0.34
chr15_67423761_67424241 0.31 1700012I11Rik
RIKEN cDNA 1700012I11 gene
197232
0.03
chr11_112779929_112780096 0.31 BC006965
cDNA sequence BC006965
1964
0.28
chr2_3657810_3658181 0.31 Gm13183
predicted gene 13183
22595
0.15
chr15_66742693_66742844 0.31 Gm17140
predicted gene 17140
1559
0.4
chr1_67194458_67194637 0.31 Gm15668
predicted gene 15668
54653
0.12
chr1_181008197_181008537 0.31 Ephx1
epoxide hydrolase 1, microsomal
9202
0.09
chr8_11149308_11149679 0.31 Gm44717
predicted gene 44717
247
0.91
chr6_116128576_116129001 0.31 Tmcc1
transmembrane and coiled coil domains 1
5115
0.17
chr2_151943059_151943241 0.30 Gm14154
predicted gene 14154
7491
0.14
chr19_36731711_36732011 0.30 Ppp1r3c
protein phosphatase 1, regulatory subunit 3C
4792
0.24
chr4_86844668_86844856 0.30 Rps6
ribosomal protein S6
12570
0.18
chr11_88897701_88897852 0.30 Gm23507
predicted gene, 23507
7345
0.13
chr16_8581750_8581949 0.30 Abat
4-aminobutyrate aminotransferase
1778
0.28
chr19_12488282_12488454 0.30 Dtx4
deltex 4, E3 ubiquitin ligase
13086
0.1
chr6_47533521_47533999 0.30 Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
1365
0.42
chr13_28416267_28416437 0.30 Gm40841
predicted gene, 40841
3511
0.31
chr8_117344375_117344531 0.30 Cmip
c-Maf inducing protein
4717
0.29
chr7_113219820_113219971 0.30 Arntl
aryl hydrocarbon receptor nuclear translocator-like
12338
0.21
chr8_126838870_126839021 0.30 A630001O12Rik
RIKEN cDNA A630001O12 gene
288
0.92
chr15_25647828_25647998 0.30 Gm48996
predicted gene, 48996
13286
0.18
chr2_69401026_69401177 0.30 Dhrs9
dehydrogenase/reductase (SDR family) member 9
20656
0.19
chr12_8003138_8004354 0.30 Apob
apolipoprotein B
8613
0.24
chr10_47642098_47642249 0.30 Gm47571
predicted gene, 47571
2050
0.49
chr8_21810141_21810292 0.30 Gm15316
predicted gene 15316
7168
0.1
chr15_55252499_55252656 0.30 Gm26296
predicted gene, 26296
10026
0.23
chr10_19990685_19990873 0.30 Map3k5
mitogen-activated protein kinase kinase kinase 5
39724
0.16
chr9_78501386_78501557 0.29 Eef1a1
eukaryotic translation elongation factor 1 alpha 1
12320
0.11
chr11_21398793_21399367 0.29 Ugp2
UDP-glucose pyrophosphorylase 2
27879
0.12
chr1_182412889_182413225 0.29 Trp53bp2
transformation related protein 53 binding protein 2
3885
0.17
chr14_101771874_101772042 0.29 Lmo7
LIM domain only 7
42001
0.13
chrX_42112143_42112724 0.29 Gm14615
predicted gene 14615
18290
0.16
chr5_72366169_72366592 0.29 Corin
corin, serine peptidase
5681
0.18
chr11_74895444_74895692 0.29 Sgsm2
small G protein signaling modulator 2
1492
0.22
chr3_65527351_65527507 0.29 4931440P22Rik
RIKEN cDNA 4931440P22 gene
755
0.39
chr13_70831157_70831325 0.29 Gm36529
predicted gene, 36529
9210
0.2
chr14_30579376_30579527 0.29 Mir3076
microRNA 3076
7302
0.14
chr15_34493251_34493646 0.29 Rida
reactive intermediate imine deaminase A homolog
1723
0.21
chr5_134440233_134440384 0.29 Gm26340
predicted gene, 26340
8266
0.11
chr14_103099863_103100150 0.29 Fbxl3
F-box and leucine-rich repeat protein 3
440
0.8
chr11_81488827_81488995 0.29 1700071K01Rik
RIKEN cDNA 1700071K01 gene
84562
0.09
chr7_139416534_139416685 0.29 Inpp5a
inositol polyphosphate-5-phosphatase A
16120
0.23
chr8_4335762_4335913 0.29 Ccl25
chemokine (C-C motif) ligand 25
3578
0.14
chr1_13103635_13103786 0.29 Prdm14
PR domain containing 14
23453
0.13
chr19_23032874_23033121 0.29 Gm50136
predicted gene, 50136
28457
0.18
chr14_93075636_93076058 0.28 Gm23509
predicted gene, 23509
62342
0.14
chr9_61422608_61422759 0.28 Tle3
transducin-like enhancer of split 3
12746
0.17
chr10_3920682_3920833 0.28 Gm23023
predicted gene, 23023
14120
0.15
chr6_133960296_133960447 0.28 Gm8956
predicted gene 8956
27962
0.17
chr15_82147771_82148080 0.28 Srebf2
sterol regulatory element binding factor 2
88
0.94
chr12_110381296_110381622 0.28 Gm47195
predicted gene, 47195
56074
0.08
chr13_32405059_32405228 0.28 Gm11381
predicted gene 11381
21455
0.21
chr4_140636700_140636879 0.28 Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
11961
0.16
chr6_8416975_8417147 0.28 Umad1
UMAP1-MVP12 associated (UMA) domain containing 1
2617
0.24
chr14_22269831_22270192 0.28 Lrmda
leucine rich melanocyte differentiation associated
40154
0.2
chr7_135609185_135609546 0.28 Ptpre
protein tyrosine phosphatase, receptor type, E
3537
0.23
chr11_100836746_100836921 0.28 Stat5b
signal transducer and activator of transcription 5B
13705
0.12
chr3_81061801_81061984 0.28 Gm16000
predicted gene 16000
21455
0.16
chr6_121878156_121878361 0.28 Mug1
murinoglobulin 1
7319
0.2
chr8_10857392_10857567 0.28 Gm32540
predicted gene, 32540
8707
0.12

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Nfatc3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0046439 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.2 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.6 GO:0009115 xanthine catabolic process(GO:0009115)
0.1 0.5 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 0.9 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.1 0.3 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.2 GO:0045472 response to ether(GO:0045472)
0.1 0.2 GO:0006203 dGTP catabolic process(GO:0006203)
0.1 0.2 GO:0030242 pexophagy(GO:0030242)
0.1 0.2 GO:0018992 germ-line sex determination(GO:0018992)
0.1 0.3 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.3 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 0.8 GO:0006577 amino-acid betaine metabolic process(GO:0006577)
0.1 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.2 GO:0032763 regulation of mast cell cytokine production(GO:0032763)
0.1 0.5 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.1 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.3 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.1 0.3 GO:2001171 positive regulation of ATP biosynthetic process(GO:2001171)
0.1 0.1 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
0.1 0.2 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.3 GO:0072675 osteoclast fusion(GO:0072675)
0.1 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.1 GO:1904754 positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
0.1 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.2 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.1 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.2 GO:0032348 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0 0.2 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 0.2 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.2 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.2 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0071332 cellular response to fructose stimulus(GO:0071332)
0.0 0.0 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.0 0.1 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.2 GO:0046499 S-adenosylmethioninamine metabolic process(GO:0046499)
0.0 0.3 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.2 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.2 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.0 0.1 GO:1903626 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.1 GO:0044838 cell quiescence(GO:0044838)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.1 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443)
0.0 0.2 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.2 GO:0030913 paranodal junction assembly(GO:0030913)
0.0 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.1 GO:2000667 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0 0.0 GO:0015744 succinate transport(GO:0015744)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.1 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.2 GO:0002488 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.0 0.1 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.0 0.0 GO:1903660 regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.2 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.9 GO:0006213 pyrimidine nucleoside metabolic process(GO:0006213)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.1 GO:0006113 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0072095 regulation of branch elongation involved in ureteric bud branching(GO:0072095)
0.0 0.1 GO:1902744 negative regulation of lamellipodium organization(GO:1902744)
0.0 0.1 GO:0070587 negative regulation of heterotypic cell-cell adhesion(GO:0034115) regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.0 0.0 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.2 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.1 GO:0036394 amylase secretion(GO:0036394)
0.0 0.2 GO:0019401 alditol biosynthetic process(GO:0019401)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.3 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0043312 neutrophil degranulation(GO:0043312)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.1 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.0 0.1 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.1 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.1 GO:0001998 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
0.0 0.2 GO:1902033 regulation of hematopoietic stem cell proliferation(GO:1902033)
0.0 0.1 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 0.2 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.0 0.2 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.0 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.3 GO:0006544 glycine metabolic process(GO:0006544)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.1 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.3 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.1 GO:2000169 regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.0 GO:0061687 detoxification of copper ion(GO:0010273) detoxification of inorganic compound(GO:0061687) stress response to copper ion(GO:1990169)
0.0 0.1 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.1 GO:1903887 motile primary cilium assembly(GO:1903887)
0.0 0.0 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.0 GO:0002432 granuloma formation(GO:0002432)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.2 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.0 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.0 0.0 GO:0006901 vesicle coating(GO:0006901)
0.0 0.0 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:1901679 pyrimidine-containing compound transmembrane transport(GO:0072531) nucleotide transmembrane transport(GO:1901679)
0.0 0.0 GO:1990791 dorsal root ganglion development(GO:1990791)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.2 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.0 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0 0.2 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.1 GO:0042559 pteridine-containing compound biosynthetic process(GO:0042559)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.0 GO:0052200 response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.0 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.1 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.2 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.1 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.0 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031)
0.0 0.0 GO:0002930 trabecular meshwork development(GO:0002930)
0.0 0.1 GO:0051031 tRNA transport(GO:0051031)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.0 GO:0018904 ether metabolic process(GO:0018904)
0.0 0.1 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.0 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0 0.0 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.1 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.0 GO:0061643 chemorepulsion of axon(GO:0061643)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.0 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.0 0.1 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.1 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.0 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.0 GO:2000041 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.0 0.1 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0018202 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.0 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.0 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.0 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:0097421 liver regeneration(GO:0097421)
0.0 0.3 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.1 GO:0060051 negative regulation of protein glycosylation(GO:0060051)
0.0 0.0 GO:0060847 endothelial cell fate specification(GO:0060847)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.0 GO:0036258 multivesicular body assembly(GO:0036258)
0.0 0.0 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.0 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.0 GO:2000564 regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.0 GO:0072282 metanephric nephron tubule morphogenesis(GO:0072282)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.0 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.1 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.1 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 0.1 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.0 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0002525 acute inflammatory response to non-antigenic stimulus(GO:0002525)
0.0 0.0 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.0 GO:0019086 late viral transcription(GO:0019086)
0.0 0.0 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 0.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.0 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.0 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:1902430 negative regulation of beta-amyloid formation(GO:1902430)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.0 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 0.0 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.0 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0 0.0 GO:0021648 vestibulocochlear nerve morphogenesis(GO:0021648)
0.0 0.1 GO:0043102 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.0 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.0 GO:0015817 histidine transport(GO:0015817)
0.0 0.2 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.0 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.0 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.0 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.0 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 0.0 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.0 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.1 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.0 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.0 GO:1903261 regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.0 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.0 0.1 GO:0009992 cellular water homeostasis(GO:0009992)
0.0 0.0 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0003097 renal water transport(GO:0003097)
0.0 0.1 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.0 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015)
0.0 0.1 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.0 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.0 GO:0046066 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.0 0.0 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.0 GO:0061110 dense core granule biogenesis(GO:0061110)
0.0 0.0 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0070627 ferrous iron import(GO:0070627) ferrous iron import into cell(GO:0097460)
0.0 0.1 GO:0070431 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0 0.0 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.0 GO:0071107 response to parathyroid hormone(GO:0071107)
0.0 0.0 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.0 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.1 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0014041 regulation of neuron maturation(GO:0014041)
0.0 0.0 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.0 0.0 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.0 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.0 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.0 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0 0.0 GO:1904415 regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.0 GO:0043309 regulation of eosinophil degranulation(GO:0043309)
0.0 0.0 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.0 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.0 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:0042635 positive regulation of hair cycle(GO:0042635)
0.0 0.0 GO:0002835 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.0 0.0 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.0 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.0 0.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.0 GO:0061511 centriole elongation(GO:0061511)
0.0 0.3 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.1 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 0.1 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.1 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.0 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.0 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.0 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.0 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.0 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.0 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
0.0 0.1 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.0 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0 0.0 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.0 0.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.0 GO:0072053 renal inner medulla development(GO:0072053)
0.0 0.1 GO:1904353 regulation of telomere capping(GO:1904353)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:0043302 positive regulation of leukocyte degranulation(GO:0043302)
0.0 0.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.0 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.0 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.0 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.0 0.0 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.0 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.0 GO:0071725 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.2 GO:0060337 type I interferon signaling pathway(GO:0060337)
0.0 0.0 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0 0.0 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0014733 regulation of skeletal muscle adaptation(GO:0014733)
0.0 0.0 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0 0.0 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.0 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.0 GO:0010916 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 0.0 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.1 GO:1903867 chorion development(GO:0060717) extraembryonic membrane development(GO:1903867)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.0 GO:0002434 immune complex clearance(GO:0002434)
0.0 0.0 GO:1902992 negative regulation of amyloid precursor protein catabolic process(GO:1902992)
0.0 0.0 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.0 GO:0060375 regulation of mast cell differentiation(GO:0060375)
0.0 0.0 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 0.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.7 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.4 GO:0044462 cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.1 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.1 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.1 0.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0038201 TOR complex(GO:0038201)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.0 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.1 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.0 0.2 GO:0031231 intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.0 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0043203 axon hillock(GO:0043203)
0.0 0.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.0 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.0 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.0 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.0 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.0 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.0 GO:1990923 PET complex(GO:1990923)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.0 GO:0035838 growing cell tip(GO:0035838)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.0 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.0 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.0 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.7 GO:0004645 phosphorylase activity(GO:0004645)
0.1 0.6 GO:0016726 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.1 0.4 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 0.6 GO:0035473 lipase binding(GO:0035473)
0.1 0.3 GO:0015154 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.6 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.5 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.2 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1 0.5 GO:0034560 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.1 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.1 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.2 GO:0042895 antibiotic transporter activity(GO:0042895)
0.1 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.1 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.0 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.1 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0 0.1 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.0 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.0 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.0 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0 0.1 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0052759 4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.3 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.0 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.0 0.1 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.0 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0031711 bradykinin receptor binding(GO:0031711)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0 0.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.0 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.5 GO:0016414 O-octanoyltransferase activity(GO:0016414)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.0 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.1 GO:0031432 titin binding(GO:0031432)
0.0 0.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.0 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0018585 fluorene oxygenase activity(GO:0018585)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.0 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.0 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.0 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.0 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.0 0.0 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.0 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0045340 mercury ion binding(GO:0045340)
0.0 0.0 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.0 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.2 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.0 GO:0019767 IgE receptor activity(GO:0019767)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.0 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.1 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.0 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.0 0.3 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.1 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.0 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.0 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.0 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.0 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.0 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.0 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.0 0.0 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.0 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0 0.0 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.0 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.0 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.0 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.0 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0015298 solute:cation antiporter activity(GO:0015298)
0.0 0.0 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.0 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.0 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.0 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.0 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.0 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.1 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.8 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 0.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.0 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.1 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.4 REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.5 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.0 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 0.1 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.1 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.0 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates