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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Nkx6-2

Z-value: 2.08

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Transcription factors associated with Nkx6-2

Gene Symbol	Gene ID	Gene Info
Nkx6-2 Ensembl NCBI MGI UniProt	ENSMUSG00000041309.11	NK6 homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr7_139559759_139559933	Nkx6-2	22944	0.166341	0.68	1.4e-01	Click!
chr7_139557259_139557436	Nkx6-2	25443	0.161011	0.65	1.6e-01	Click!

Activity of the Nkx6-2 motif across conditions

Conditions sorted by the z-value of the Nkx6-2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr13_20205112_20205287	1.75	Elmo1	engulfment and cell motility 1	19992	0.25
chr12_21190031_21190182	1.60	AC156032.1		57217	0.09
chr12_9173565_9173884	1.44	Ttc32	tetratricopeptide repeat domain 32	143696	0.04
chr2_33444795_33444946	1.44	Gm13536	predicted gene 13536	1932	0.27
chr5_110596813_110596964	1.43	Galnt9	polypeptide N-acetylgalactosaminyltransferase 9	6633	0.15
chr4_123576766_123577231	1.34	Macf1	microtubule-actin crosslinking factor 1	3938	0.22
chr19_26731899_26732052	1.32	Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	1976	0.4
chr2_22587937_22588311	1.31	Gm13341	predicted gene 13341	162	0.91
chr9_33052418_33052986	1.19	Gm27166	predicted gene 27166	20911	0.22
chr4_118129721_118129877	1.15	St3gal3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	5083	0.18
chr12_118887325_118887612	1.14	Abcb5	ATP-binding cassette, sub-family B (MDR/TAP), member 5	3291	0.3
chr6_72624193_72624362	1.12	Gm15401	predicted gene 15401	5011	0.09
chr17_86710487_86710973	1.12	Gm22235	predicted gene, 22235	7323	0.19
chr9_35196767_35196923	1.09	Tirap	toll-interleukin 1 receptor (TIR) domain-containing adaptor protein	2654	0.14
chr9_80172684_80172835	1.08	Myo6	myosin VI	7532	0.2
chr14_70338039_70338256	1.04	Slc39a14	solute carrier family 39 (zinc transporter), member 14	3949	0.15
chr3_121272792_121272948	1.04	Gm30517	predicted gene, 30517	4654	0.16
chr3_116409014_116409188	1.02	Cdc14a	CDC14 cell division cycle 14A	3613	0.2
chr17_83938813_83938978	1.01	Gm23905	predicted gene, 23905	8693	0.12
chr18_34868711_34868905	1.00	Egr1	early growth response 1	7601	0.14
chr7_122666197_122666401	1.00	Cacng3	calcium channel, voltage-dependent, gamma subunit 3	4193	0.22
chr12_41451963_41452119	1.00	Lrrn3	leucine rich repeat protein 3, neuronal	34390	0.15
chr4_120986544_120986936	1.00	Smap2	small ArfGAP 2	11032	0.12
chr1_24612849_24613004	0.99	Gm28438	predicted gene 28438	193	0.45
chr18_8939044_8939213	0.99	Gm37148	predicted gene, 37148	10893	0.24
chr2_158859600_158859775	0.96	Dhx35	DEAH (Asp-Glu-Ala-His) box polypeptide 35	9058	0.25
chr19_37540374_37540594	0.94	Exoc6	exocyst complex component 6	9934	0.2
chr10_43245095_43245284	0.94	Pdss2	prenyl (solanesyl) diphosphate synthase, subunit 2	23453	0.16
chr1_72226614_72226900	0.92	Gm25360	predicted gene, 25360	517	0.69
chr13_52976525_52976676	0.91	Nfil3	nuclear factor, interleukin 3, regulated	4473	0.2
chr12_109991265_109991416	0.91	Gm34667	predicted gene, 34667	32533	0.1
chr6_38920215_38920417	0.89	Tbxas1	thromboxane A synthase 1, platelet	1292	0.48
chr8_108706681_108707155	0.89	Zfhx3	zinc finger homeobox 3	3818	0.29
chr13_102858710_102858861	0.89	Mast4	microtubule associated serine/threonine kinase family member 4	47001	0.17
chr1_66895610_66896410	0.89	Gm25832	predicted gene, 25832	29213	0.09
chr13_3635068_3635349	0.88	Asb13	ankyrin repeat and SOCS box-containing 13	1109	0.45
chr18_80934281_80934433	0.87	Atp9b	ATPase, class II, type 9B	297	0.88
chr19_53554531_53554692	0.87	Gm50394	predicted gene, 50394	24956	0.11
chr15_57926003_57926154	0.86	Tbc1d31	TBC1 domain family, member 31	10065	0.19
chr10_128072013_128072177	0.86	Ptges3	prostaglandin E synthase 3	2823	0.11
chr6_59032854_59033027	0.86	Gm19165	predicted gene, 19165	3949	0.2
chr13_80895235_80895839	0.84	Arrdc3	arrestin domain containing 3	5019	0.18
chr16_95709296_95709447	0.83	Ets2	E26 avian leukemia oncogene 2, 3' domain	3032	0.28
chr6_85823511_85823680	0.83	Nat8f5	N-acetyltransferase 8 (GCN5-related) family member 5	2623	0.13
chr2_48442189_48442365	0.82	Gm13481	predicted gene 13481	14968	0.23
chr11_109733399_109733703	0.82	Fam20a	family with sequence similarity 20, member A	11272	0.17
chr6_52725129_52725352	0.82	Gm43967	predicted gene, 43967	2310	0.24
chr7_140112202_140112371	0.81	Paox	polyamine oxidase (exo-N4-amino)	3513	0.11
chr9_123530850_123531001	0.80	Sacm1l	SAC1 suppressor of actin mutations 1-like (yeast)	1043	0.5
chr3_83048126_83048370	0.79	Fgb	fibrinogen beta chain	1615	0.3
chr19_23024753_23025259	0.78	Gm50136	predicted gene, 50136	36448	0.17
chr2_131180305_131180466	0.78	Cenpb	centromere protein B	318	0.78
chr15_4561546_4561984	0.76	C6	complement component 6	165410	0.03
chr10_19991304_19991477	0.76	Map3k5	mitogen-activated protein kinase kinase kinase 5	40335	0.16
chr8_124483410_124483561	0.76	Cog2	component of oligomeric golgi complex 2	37282	0.13
chr16_91565059_91565210	0.76	Ifngr2	interferon gamma receptor 2	3811	0.13
chr16_30953629_30953810	0.75	Gm46565	predicted gene, 46565	18090	0.15
chr9_54941980_54942143	0.74	Psma4	proteasome subunit alpha 4	8729	0.13
chr13_64244809_64244979	0.74	Cdc14b	CDC14 cell division cycle 14B	3748	0.13
chr3_10284727_10284890	0.74	Fabp12	fatty acid binding protein 12	16366	0.09
chr3_132917768_132917922	0.74	Npnt	nephronectin	11486	0.16
chr4_149453846_149453997	0.74	Rbp7	retinol binding protein 7, cellular	497	0.65
chr19_28520868_28521034	0.74	Glis3	GLIS family zinc finger 3	19469	0.24
chr14_19709778_19709943	0.73	Gm49341	predicted gene, 49341	12651	0.13
chr6_95819185_95819380	0.73	Suclg2	succinate-Coenzyme A ligase, GDP-forming, beta subunit	100482	0.08
chr7_34197763_34198034	0.73	Pdcd2l	programmed cell death 2-like	1237	0.27
chr19_46111005_46111156	0.73	Gm50306	predicted gene, 50306	13850	0.11
chr1_4859119_4859327	0.72	Tcea1	transcription elongation factor A (SII) 1	1185	0.36
chr15_77822103_77822481	0.72	Myh9	myosin, heavy polypeptide 9, non-muscle	9061	0.15
chr13_31440719_31440893	0.72	Gm23351	predicted gene, 23351	13551	0.17
chr12_80760650_80760809	0.72	Ccdc177	coiled-coil domain containing 177	42	0.96
chr2_155059266_155059435	0.71	a	nonagouti	11735	0.13
chr14_116308331_116308711	0.71	Gm20713	predicted gene 20713	437243	0.01
chr13_46630725_46630884	0.70	Cap2	CAP, adenylate cyclase-associated protein, 2 (yeast)	9254	0.17
chr5_140812966_140813117	0.70	Gna12	guanine nucleotide binding protein, alpha 12	17116	0.2
chr3_133765600_133766533	0.70	Gm6135	prediticted gene 6135	25438	0.2
chr7_28411283_28411456	0.69	Samd4b	sterile alpha motif domain containing 4B	2538	0.12
chr4_80004164_80004316	0.69	Gm11410	predicted gene 11410	251	0.57
chr3_101430854_101431043	0.69	Gm42538	predicted gene 42538	4012	0.19
chr5_130193066_130193248	0.69	Ndufa12-ps	NADH:ubiquinone oxidoreductase subunit A12, pseudogene	4762	0.11
chr3_14723573_14723829	0.68	Gm5843	predicted gene 5843	1285	0.47
chr15_3278636_3279064	0.68	Selenop	selenoprotein P	6765	0.22
chr17_72896357_72896515	0.67	Lbh	limb-bud and heart	21869	0.21
chr9_110531506_110531683	0.67	Setd2	SET domain containing 2	1003	0.46
chr12_40561876_40562268	0.67	Dock4	dedicator of cytokinesis 4	115736	0.06
chr4_80003665_80003823	0.66	Gm11408	predicted gene 11408	170	0.59
chr8_71405347_71405498	0.66	Ankle1	ankyrin repeat and LEM domain containing 1	588	0.54
chr11_20165820_20166001	0.66	Gm12031	predicted gene 12031	19566	0.14
chr10_108350464_108350766	0.65	Gm23105	predicted gene, 23105	13050	0.19
chr9_72530347_72530501	0.65	4930509E16Rik	RIKEN cDNA 4930509E16 gene	1434	0.22
chr13_10447671_10447864	0.65	Gm47407	predicted gene, 47407	69920	0.1
chr4_117230931_117231159	0.65	1700012C08Rik	RIKEN cDNA 1700012C08 gene	17263	0.07
chr18_54990868_54991280	0.65	Gm4221	predicted gene 4221	764	0.47
chr2_48816834_48817005	0.65	Acvr2a	activin receptor IIA	2810	0.3
chr15_59046761_59047065	0.64	Mtss1	MTSS I-BAR domain containing 1	6316	0.23
chr14_22269831_22270192	0.64	Lrmda	leucine rich melanocyte differentiation associated	40154	0.2
chr7_112324378_112324529	0.64	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	8424	0.29
chr12_111588664_111589225	0.64	Mark3	MAP/microtubule affinity regulating kinase 3	794	0.49
chr7_84112155_84112947	0.64	Cemip	cell migration inducing protein, hyaluronan binding	26049	0.14
chr15_29829703_29829875	0.64	Gm23033	predicted gene, 23033	58685	0.14
chr5_9056138_9056296	0.63	Gm40264	predicted gene, 40264	21093	0.14
chr5_12476907_12477068	0.63	Gm8925	predicted gene 8925	2641	0.3
chr7_45264516_45264678	0.63	Slc6a16	solute carrier family 6, member 16	3553	0.09
chr5_75961858_75962064	0.63	Kdr	kinase insert domain protein receptor	16497	0.17
chr1_157505070_157505337	0.63	Sec16b	SEC16 homolog B (S. cerevisiae)	1525	0.34
chr2_165015545_165015729	0.63	Ncoa5	nuclear receptor coactivator 5	7576	0.14
chr13_58999542_58999699	0.62	Gm34245	predicted gene, 34245	78676	0.08
chr13_24945328_24945479	0.62	Gpld1	glycosylphosphatidylinositol specific phospholipase D1	2251	0.21
chr6_129526737_129526938	0.62	Gm44120	predicted gene, 44120	4275	0.09
chr1_59399079_59399261	0.62	Gm29016	predicted gene 29016	20240	0.17
chr2_12899219_12899529	0.62	Pter	phosphotriesterase related	24667	0.21
chr17_13819245_13819528	0.61	Afdn	afadin, adherens junction formation factor	31576	0.13
chr19_29268750_29269067	0.61	Jak2	Janus kinase 2	16467	0.17
chr9_70651277_70651437	0.61	Gm10642	predicted gene 10642	4894	0.18
chrX_36126402_36126763	0.61	Il13ra1	interleukin 13 receptor, alpha 1	14472	0.2
chr2_156145846_156146301	0.60	Romo1	reactive oxygen species modulator 1	1833	0.18
chr4_116695063_116695819	0.60	Prdx1	peroxiredoxin 1	8129	0.1
chr11_113725344_113725520	0.60	Cdc42ep4	CDC42 effector protein (Rho GTPase binding) 4	13890	0.12
chr9_66285727_66286140	0.60	Dapk2	death-associated protein kinase 2	17559	0.2
chr10_68269443_68270351	0.60	Arid5b	AT rich interactive domain 5B (MRF1-like)	8824	0.23
chr5_135741186_135741337	0.60	Tmem120a	transmembrane protein 120A	1138	0.32
chr2_50331434_50331615	0.60	Gm13483	predicted gene 13483	34619	0.15
chr7_14430420_14431121	0.60	Sult2a8	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8	5677	0.17
chr10_79969116_79969470	0.59	Grin3b	glutamate receptor, ionotropic, NMDA3B	1422	0.17
chr16_30827849_30828032	0.59	Gm26295	predicted gene, 26295	13778	0.14
chr2_84650666_84651104	0.59	Ctnnd1	catenin (cadherin associated protein), delta 1	120	0.92
chr2_172690322_172690473	0.59	Tfap2c	transcription factor AP-2, gamma	138281	0.04
chr14_27301985_27302171	0.58	Arhgef3	Rho guanine nucleotide exchange factor (GEF) 3	33988	0.16
chr1_118595487_118595650	0.58	Clasp1	CLIP associating protein 1	9159	0.17
chr6_134486269_134486420	0.58	Lrp6	low density lipoprotein receptor-related protein 6	15051	0.19
chr2_69061493_69062160	0.58	Gm38377	predicted gene, 38377	43730	0.11
chr17_29493598_29493749	0.58	Pim1	proviral integration site 1	266	0.83
chr10_28648331_28648493	0.58	Themis	thymocyte selection associated	19948	0.24
chr8_24445565_24445716	0.57	Gm44620	predicted gene 44620	1457	0.34
chr10_61486909_61487060	0.57	Gm47595	predicted gene, 47595	9306	0.1
chr15_79327440_79327599	0.57	Pla2g6	phospholipase A2, group VI	445	0.7
chr4_75260081_75260473	0.57	Dmac1	distal membrane arm assembly complex 1	18028	0.19
chr5_21053272_21053655	0.57	Ptpn12	protein tyrosine phosphatase, non-receptor type 12	2262	0.26
chr12_80956924_80957266	0.57	Srsf5	serine and arginine-rich splicing factor 5	10719	0.13
chr1_86606018_86606363	0.57	Cops7b	COP9 signalosome subunit 7B	9450	0.12
chr9_79213455_79213848	0.57	Gm47499	predicted gene, 47499	11644	0.17
chr8_117718576_117718739	0.57	Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	2279	0.22
chr18_38431542_38431707	0.56	Ndfip1	Nedd4 family interacting protein 1	12640	0.15
chr19_10188246_10188628	0.56	Mir6993	microRNA 6993	2938	0.13
chr6_121872993_121873786	0.56	Mug1	murinoglobulin 1	12188	0.19
chr1_58144709_58145117	0.56	Gm24548	predicted gene, 24548	10175	0.19
chr4_101217357_101217554	0.56	Gm12785	predicted gene 12785	6868	0.16
chr2_62386509_62386700	0.55	Dpp4	dipeptidylpeptidase 4	8356	0.19
chr11_115832980_115833291	0.55	Llgl2	LLGL2 scribble cell polarity complex component	790	0.45
chr2_145855907_145856101	0.55	Rin2	Ras and Rab interactor 2	6640	0.18
chr15_82399716_82400045	0.55	Cyp2d11	cytochrome P450, family 2, subfamily d, polypeptide 11	5858	0.06
chr11_83922736_83922899	0.55	Ddx52	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52	19245	0.16
chr6_115856128_115856300	0.55	Ift122	intraflagellar transport 122	2569	0.15
chr5_117293923_117294074	0.55	Gm3786	predicted gene 3786	408	0.73
chr13_119709262_119709436	0.55	Gm48342	predicted gene, 48342	4800	0.13
chrX_42112143_42112724	0.54	Gm14615	predicted gene 14615	18290	0.16
chr8_95802952_95803118	0.54	4930513N10Rik	RIKEN cDNA 4930513N10 gene	3709	0.11
chr5_9038233_9038384	0.54	Gm40264	predicted gene, 40264	3184	0.2
chr12_106478851_106479125	0.53	Gm3191	predicted gene 3191	19838	0.16
chr1_86700604_86700771	0.53	Dis3l2	DIS3 like 3'-5' exoribonuclease 2	3121	0.19
chrX_11018346_11018497	0.53	Gm14485	predicted gene 14485	2586	0.39
chr4_86654136_86654503	0.53	Plin2	perilipin 2	4325	0.19
chr19_46304529_46304702	0.52	Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100	129	0.88
chr5_145975985_145976140	0.52	Gm43115	predicted gene 43115	7652	0.13
chr6_124687352_124687512	0.52	Lpcat3	lysophosphatidylcholine acyltransferase 3	13987	0.06
chr13_23746567_23746739	0.52	H2bc3	H2B clustered histone 3	81	0.52
chr8_107396318_107396469	0.52	Nqo1	NAD(P)H dehydrogenase, quinone 1	6813	0.15
chr3_69120460_69120611	0.52	Gm37558	predicted gene, 37558	2189	0.22
chr8_94549535_94549827	0.52	Cpne2	copine II	5833	0.14
chr4_98923398_98923571	0.52	Usp1	ubiquitin specific peptidase 1	326	0.89
chr8_87478323_87478484	0.51	Gm2694	predicted gene 2694	5009	0.13
chr19_7802461_7802861	0.51	Slc22a26	solute carrier family 22 (organic cation transporter), member 26	6	0.98
chr13_100577098_100577269	0.51	Gm8847	predicted gene 8847	17151	0.1
chr3_85974229_85974402	0.51	Sh3d19	SH3 domain protein D19	3206	0.14
chr6_143482695_143483407	0.51	Gm23272	predicted gene, 23272	17654	0.24
chr10_63121597_63121800	0.50	Mypn	myopalladin	986	0.43
chr11_88852680_88852905	0.50	4930556N13Rik	RIKEN cDNA 4930556N13 gene	1188	0.33
chr2_71739293_71739468	0.50	Gm13647	predicted gene 13647	1565	0.27
chr13_107600306_107600483	0.50	Gm32090	predicted gene, 32090	12455	0.22
chr10_122434762_122434913	0.50	Avpr1a	arginine vasopressin receptor 1A	13662	0.19
chr13_100543031_100543362	0.50	Ocln	occludin	9264	0.12
chr2_161108035_161108225	0.50	Chd6	chromodomain helicase DNA binding protein 6	874	0.49
chr6_34728924_34729082	0.50	Npn2	neoplastic progression 2	2097	0.23
chr19_30195816_30196018	0.50	Gldc	glycine decarboxylase	20488	0.17
chr7_19965081_19965263	0.50	Ceacam20	carcinoembryonic antigen-related cell adhesion molecule 20	240	0.83
chr11_54339986_54340211	0.49	Acsl6	acyl-CoA synthetase long-chain family member 6	4601	0.16
chr5_24696900_24697051	0.49	Gm26648	predicted gene, 26648	7715	0.13
chr18_12202319_12202472	0.49	Npc1	NPC intracellular cholesterol transporter 1	6988	0.14
chr5_103659682_103659843	0.49	Gm25721	predicted gene, 25721	1525	0.29
chr6_94259180_94259540	0.49	Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	23665	0.22
chr11_101395003_101395405	0.49	Gm25475	predicted gene, 25475	2564	0.09
chr16_23319629_23319807	0.49	St6gal1	beta galactoside alpha 2,6 sialyltransferase 1	29248	0.15
chr10_115312586_115313221	0.49	Rab21	RAB21, member RAS oncogene family	2688	0.2
chr17_30139008_30139298	0.49	Zfand3	zinc finger, AN1-type domain 3	2963	0.25
chr17_32327137_32327293	0.48	Akap8l	A kinase (PRKA) anchor protein 8-like	5684	0.13
chr13_111856965_111857371	0.48	Gm15324	predicted gene 15324	172	0.93
chr12_83921974_83922149	0.48	Numb	NUMB endocytic adaptor protein	127	0.94
chr4_11865116_11865283	0.48	Gm25002	predicted gene, 25002	83688	0.07
chr5_92858921_92859073	0.48	Shroom3	shroom family member 3	2526	0.33
chr10_13869899_13870050	0.48	Aig1	androgen-induced 1	994	0.37

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx6-2

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.1	0.4	GO:0060300	regulation of cytokine activity(GO:0060300)
0.1	0.7	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.1	0.4	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1	0.3	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.1	0.3	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.1	0.4	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1	0.5	GO:0046133	pyrimidine ribonucleoside catabolic process(GO:0046133)
0.1	0.3	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.1	0.3	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.1	0.3	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1	0.2	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.1	0.2	GO:0036015	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1	0.4	GO:0015722	canalicular bile acid transport(GO:0015722)
0.1	0.2	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1	0.3	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1	0.2	GO:0006172	ADP biosynthetic process(GO:0006172)
0.1	0.5	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.1	0.3	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.1	0.3	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1	0.3	GO:0072015	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1	0.2	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	0.3	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1	0.2	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.1	0.2	GO:0014858	positive regulation of skeletal muscle cell proliferation(GO:0014858)
0.1	0.2	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.9	GO:0072673	lamellipodium morphogenesis(GO:0072673)
0.1	0.2	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1	0.3	GO:0009115	xanthine catabolic process(GO:0009115)
0.1	0.1	GO:0043134	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.1	0.5	GO:0021873	forebrain neuroblast division(GO:0021873)
0.1	0.3	GO:0042713	sperm ejaculation(GO:0042713)
0.1	0.2	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.1	0.7	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
0.1	0.1	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.1	0.2	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1	0.4	GO:0002591	positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591)
0.1	0.2	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1	0.5	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.1	0.2	GO:2000321	positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.1	0.2	GO:0072566	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.1	0.2	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.1	0.4	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.1	0.4	GO:0097012	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1	0.3	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.1	0.2	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1	0.2	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.3	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.3	GO:0044539	long-chain fatty acid import(GO:0044539)
0.0	0.1	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.2	GO:0072095	regulation of branch elongation involved in ureteric bud branching(GO:0072095)
0.0	0.1	GO:0002017	regulation of blood volume by renal aldosterone(GO:0002017)
0.0	0.1	GO:0035513	oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0	0.4	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.0	0.1	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0	0.1	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.1	GO:0072223	metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.0	0.4	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.0	0.1	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.1	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.0	0.3	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.1	GO:0007227	signal transduction downstream of smoothened(GO:0007227)
0.0	0.1	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.2	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0	0.1	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.4	GO:0010744	positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.0	0.2	GO:0090166	Golgi disassembly(GO:0090166)
0.0	0.1	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.1	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.0	0.1	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.1	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.0	0.1	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.2	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0	0.2	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.0	0.5	GO:0002467	germinal center formation(GO:0002467)
0.0	0.2	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.1	GO:0038109	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0	0.1	GO:0060268	negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.0	0.1	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.0	0.2	GO:0051256	mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.2	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.1	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.0	0.2	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.3	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.0	0.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0	0.0	GO:0040038	polar body extrusion after meiotic divisions(GO:0040038)
0.0	0.1	GO:0019244	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.1	GO:0071332	cellular response to fructose stimulus(GO:0071332)
0.0	0.1	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.2	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.1	GO:0097503	sialylation(GO:0097503)
0.0	0.2	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.1	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.1	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.1	GO:0035963	response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0	0.1	GO:0046208	spermine catabolic process(GO:0046208)
0.0	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.4	GO:0035278	miRNA mediated inhibition of translation(GO:0035278)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.1	GO:0071476	cellular hypotonic response(GO:0071476)
0.0	0.1	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0	0.1	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0	0.1	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0	0.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.1	GO:0031392	regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.0	0.1	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0	0.1	GO:0002317	plasma cell differentiation(GO:0002317)
0.0	0.2	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.2	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.2	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.1	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.3	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.1	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.1	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0	0.2	GO:0097264	self proteolysis(GO:0097264)
0.0	0.0	GO:0021943	formation of radial glial scaffolds(GO:0021943)
0.0	0.1	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.0	0.1	GO:0090148	membrane fission(GO:0090148)
0.0	0.0	GO:2000481	positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0	0.1	GO:1904668	positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0	0.1	GO:0045915	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.1	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.1	GO:0008595	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.1	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.4	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0071073	positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0	0.2	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:1903054	negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.2	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.1	GO:1904705	regulation of vascular smooth muscle cell proliferation(GO:1904705) vascular smooth muscle cell proliferation(GO:1990874)
0.0	0.1	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.0	0.1	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.0	0.1	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.0	0.4	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.1	GO:0034116	positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0	0.0	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
0.0	0.1	GO:0097070	ductus arteriosus closure(GO:0097070)
0.0	0.0	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242)
0.0	0.1	GO:0070889	platelet alpha granule organization(GO:0070889)
0.0	0.1	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:0060332	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.0	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.2	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.0	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.0	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.0	0.1	GO:0090365	regulation of mRNA modification(GO:0090365)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.2	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.1	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0	0.2	GO:0021702	cerebellar Purkinje cell differentiation(GO:0021702)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.0	0.1	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.1	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0	0.1	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.1	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0	0.0	GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.0	0.1	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0	0.1	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0030576	Cajal body organization(GO:0030576)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0015766	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.1	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.1	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0	0.2	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.1	GO:0097384	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.2	GO:0042635	positive regulation of hair cycle(GO:0042635)
0.0	0.3	GO:0060337	type I interferon signaling pathway(GO:0060337)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.0	GO:0061092	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0	0.1	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0	0.1	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0	0.2	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.0	GO:0007403	glial cell fate determination(GO:0007403)
0.0	0.1	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.1	GO:0001907	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.1	GO:0030035	microspike assembly(GO:0030035)
0.0	0.1	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.0	0.1	GO:1904219	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.1	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.3	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0	0.0	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.0	0.0	GO:1902416	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0	0.0	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0	0.3	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.2	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0002756	MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0	0.1	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.1	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.1	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	0.1	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838)
0.0	0.4	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.4	GO:0090662	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.0	GO:0046098	guanine metabolic process(GO:0046098)
0.0	0.1	GO:1901026	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0	0.1	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.2	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.0	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.0	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.0	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.0	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.3	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.0	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.0	GO:0015888	thiamine transport(GO:0015888)
0.0	0.1	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0	0.3	GO:0031571	mitotic G1 DNA damage checkpoint(GO:0031571) mitotic G1/S transition checkpoint(GO:0044819)
0.0	0.0	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.0	0.1	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0	0.0	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.0	GO:1900221	regulation of beta-amyloid clearance(GO:1900221)
0.0	0.0	GO:0002838	negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.0	0.0	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0	0.1	GO:0071404	cellular response to low-density lipoprotein particle stimulus(GO:0071404)
0.0	0.1	GO:0070126	mitochondrial translational termination(GO:0070126)
0.0	0.1	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0	0.0	GO:0000087	mitotic M phase(GO:0000087)
0.0	0.1	GO:0031269	pseudopodium assembly(GO:0031269)
0.0	0.0	GO:0045415	negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.0	0.0	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.0	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.1	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.0	GO:1903753	negative regulation of p38MAPK cascade(GO:1903753)
0.0	0.0	GO:0006533	aspartate catabolic process(GO:0006533)
0.0	0.0	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.1	GO:0032070	regulation of deoxyribonuclease activity(GO:0032070)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.0	GO:0000710	meiotic mismatch repair(GO:0000710)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.0	GO:2000327	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0	0.2	GO:0044144	regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0	0.1	GO:0045332	phospholipid translocation(GO:0045332)
0.0	0.1	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.0	GO:1903116	positive regulation of actin filament-based movement(GO:1903116)
0.0	0.0	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.0	GO:0001983	baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0	0.0	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0	0.1	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.0	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.0	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.0	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0	0.0	GO:0044778	meiotic DNA integrity checkpoint(GO:0044778)
0.0	0.0	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.0	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.0	0.0	GO:0044857	plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
0.0	0.0	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.0	0.2	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.1	GO:0090037	positive regulation of protein kinase C signaling(GO:0090037)
0.0	0.3	GO:0046627	negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0	0.0	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.0	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0	0.0	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.0	GO:0002175	protein localization to paranode region of axon(GO:0002175) paranodal junction assembly(GO:0030913)
0.0	0.1	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.1	GO:1900746	regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.0	0.0	GO:0010992	ubiquitin homeostasis(GO:0010992)
0.0	0.0	GO:0009436	glyoxylate catabolic process(GO:0009436)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0060751	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0	0.1	GO:0033127	regulation of histone phosphorylation(GO:0033127)
0.0	0.0	GO:0051383	kinetochore organization(GO:0051383)
0.0	0.0	GO:0010749	regulation of nitric oxide mediated signal transduction(GO:0010749)
0.0	0.1	GO:0098734	protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0	0.0	GO:0010612	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0	0.1	GO:0071501	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.0	GO:2000259	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0	0.0	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.0	0.2	GO:0001702	gastrulation with mouth forming second(GO:0001702)
0.0	0.0	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.0	GO:0034653	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0	0.0	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.0	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.0	0.0	GO:0046061	dATP catabolic process(GO:0046061)
0.0	0.0	GO:0052055	modulation by symbiont of host molecular function(GO:0052055)
0.0	0.1	GO:1901663	quinone biosynthetic process(GO:1901663)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.0	GO:1902226	regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0	0.1	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0051410	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0	0.0	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.0	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.0	0.1	GO:0043383	negative T cell selection(GO:0043383)
0.0	0.0	GO:0009750	response to fructose(GO:0009750)
0.0	0.1	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.0	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.0	GO:0000032	cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
0.0	0.0	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.0	0.0	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.3	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0035061	interchromatin granule(GO:0035061)
0.1	0.6	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.5	GO:0005915	zonula adherens(GO:0005915)
0.1	0.5	GO:0031209	SCAR complex(GO:0031209)
0.1	0.3	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1	0.4	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.1	0.3	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1	0.5	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.6	GO:0071564	npBAF complex(GO:0071564)
0.1	1.1	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.3	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.3	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.1	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.2	GO:0061574	ASAP complex(GO:0061574)
0.0	0.2	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.1	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.1	GO:0097513	myosin II filament(GO:0097513)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.1	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0	0.2	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.3	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.2	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.0	0.2	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.2	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.1	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.1	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.0	0.6	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.1	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.0	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.3	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.0	0.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.2	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.1	GO:0042627	chylomicron(GO:0042627)
0.0	0.1	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	0.1	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.2	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.1	GO:0045180	basal cortex(GO:0045180)
0.0	0.3	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.0	GO:0097413	Lewy body(GO:0097413)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.2	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.1	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.4	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.0	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:0035363	histone locus body(GO:0035363)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0090543	Flemming body(GO:0090543)
0.0	0.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.0	GO:1990923	PET complex(GO:1990923)
0.0	0.2	GO:1902562	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.0	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.0	0.0	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0	0.0	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.0	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.0	0.2	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.2	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.0	GO:0070876	SOSS complex(GO:0070876)
0.0	0.0	GO:0071437	invadopodium(GO:0071437)
0.0	0.0	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.4	GO:0000152	nuclear ubiquitin ligase complex(GO:0000152)
0.0	0.1	GO:0070847	core mediator complex(GO:0070847)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0003696	satellite DNA binding(GO:0003696)
0.1	0.4	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.1	0.4	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.1	1.1	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.3	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.1	0.3	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.4	GO:0004630	phospholipase D activity(GO:0004630)
0.1	0.4	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1	0.3	GO:0016726	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.1	0.2	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.1	0.2	GO:0031893	vasopressin receptor binding(GO:0031893)
0.1	0.3	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1	0.2	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.1	0.2	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.1	0.3	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1	0.4	GO:0036122	BMP binding(GO:0036122)
0.1	0.2	GO:0019961	interferon binding(GO:0019961)
0.0	0.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.3	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.4	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.1	GO:0030519	snoRNP binding(GO:0030519)
0.0	0.1	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.1	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.0	0.3	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.0	0.5	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.2	GO:0005534	galactose binding(GO:0005534)
0.0	0.5	GO:0019841	retinol binding(GO:0019841)
0.0	0.1	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0	0.2	GO:0031749	D2 dopamine receptor binding(GO:0031749)
0.0	0.3	GO:0015321	sodium:phosphate symporter activity(GO:0005436) sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.4	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0	0.3	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.1	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.2	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	1.0	GO:0045296	cadherin binding(GO:0045296)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.0	0.2	GO:0035473	lipase binding(GO:0035473)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.3	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.6	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.2	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.2	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.2	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.3	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.2	GO:0031432	titin binding(GO:0031432)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0	0.1	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.1	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.2	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.0	0.1	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.1	GO:0031782	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.2	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.0	GO:1901612	cardiolipin binding(GO:1901612)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.2	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.0	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.1	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0	0.1	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.0	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.2	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.2	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.7	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.0	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0015157	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.0	GO:0051373	FATZ binding(GO:0051373)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.3	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.1	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.2	GO:0031690	adrenergic receptor binding(GO:0031690)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.3	GO:0001614	purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.2	GO:0016594	glycine binding(GO:0016594)
0.0	0.2	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0071253	connexin binding(GO:0071253)
0.0	0.0	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.9	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.0	GO:0030984	kininogen binding(GO:0030984)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.3	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:1990254	keratin filament binding(GO:1990254)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.2	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.2	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.0	0.1	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.1	GO:0016936	galactoside binding(GO:0016936)
0.0	0.1	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
0.0	0.1	GO:0070061	fructose binding(GO:0070061)
0.0	0.1	GO:0018651	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0	0.1	GO:0052832	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.0	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0001013	RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0	0.1	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.2	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0032183	SUMO binding(GO:0032183)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.4	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.0	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.2	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.0	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.0	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.2	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.0	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0015266	protein channel activity(GO:0015266)
0.0	0.1	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.0	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.0	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0	0.1	GO:0000150	recombinase activity(GO:0000150)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.0	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.1	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	0.1	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.3	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.9	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.0	GO:0070698	type I activin receptor binding(GO:0070698)
0.0	0.5	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.0	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.2	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.0	GO:0019776	Atg8 ligase activity(GO:0019776)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	0.3	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.3	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.8	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.2	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	1.1	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.7	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.1	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.1	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	PID FOXO PATHWAY	FoxO family signaling
0.0	0.3	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.0	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.3	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.7	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.8	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.1	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.5	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.2	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.2	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.3	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.4	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.2	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.1	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.3	PID INSULIN PATHWAY	Insulin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	0.5	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	0.4	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.7	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.1	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.0	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.6	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	1.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.4	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.4	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.4	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.1	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.4	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.6	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.5	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.3	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.0	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.2	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.2	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.0	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.3	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport

Results for Nkx6-2

Z-value: 2.08

Motif logo

Transcription factors associated with Nkx6-2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Nkx6-2 motif across conditions

Conditions sorted by the z-value of the Nkx6-2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx6-2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: