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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Nr2e1

Z-value: 0.89

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Transcription factors associated with Nr2e1

Gene Symbol	Gene ID	Gene Info
Nr2e1 Ensembl NCBI MGI UniProt	ENSMUSG00000019803.5	Nr2e1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Nr2e1	chr10_42538714_42538885	30029	0.145705	0.80	5.4e-02	Click!

Activity of the Nr2e1 motif across conditions

Conditions sorted by the z-value of the Nr2e1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_146107597_146107748	1.37	Cyp3a59	cytochrome P450, family 3, subfamily a, polypeptide 59	28405	0.11
chr5_118292276_118292427	0.98	Gm25076	predicted gene, 25076	25902	0.16
chr5_145982849_145983558	0.94	Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	8440	0.13
chr3_88628445_88628599	0.93	Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2	920	0.37
chr10_115348229_115348396	0.83	Tmem19	transmembrane protein 19	752	0.58
chr10_122408778_122408952	0.82	Gm36041	predicted gene, 36041	21973	0.18
chr9_78022696_78022864	0.74	Gm47829	predicted gene, 47829	5165	0.12
chr14_19839858_19840045	0.61	D14Ertd670e	DNA segment, Chr 14, ERATO Doi 670, expressed	1026	0.48
chr8_73114845_73115014	0.60	Large1	LARGE xylosyl- and glucuronyltransferase 1	16016	0.24
chr10_28078586_28078966	0.59	Ptprk	protein tyrosine phosphatase, receptor type, K	3766	0.28
chr4_118129721_118129877	0.58	St3gal3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	5083	0.18
chr11_107109633_107109941	0.58	Bptf	bromodomain PHD finger transcription factor	22135	0.14
chr15_8968437_8968609	0.56	Ranbp3l	RAN binding protein 3-like	97	0.97
chr5_98996002_98996174	0.54	Gm3470	predicted gene 3470	26134	0.2
chr3_101953485_101953642	0.49	Slc22a15	solute carrier family 22 (organic anion/cation transporter), member 15	29110	0.17
chr17_24797110_24797261	0.48	Meiob	meiosis specific with OB domains	7104	0.09
chr7_101491003_101491309	0.46	Pde2a	phosphodiesterase 2A, cGMP-stimulated	9871	0.14
chr19_41838995_41839153	0.46	Frat2	frequently rearranged in advanced T cell lymphomas 2	9058	0.14
chr12_84939464_84939615	0.45	Arel1	apoptosis resistant E3 ubiquitin protein ligase 1	3839	0.15
chr9_66327050_66327224	0.45	Herc1	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1	23313	0.17
chr11_50733265_50733435	0.45	Gm12200	predicted gene 12200	7806	0.16
chr6_30286706_30286895	0.44	Ube2h	ubiquitin-conjugating enzyme E2H	17722	0.14
chr19_33094946_33095121	0.44	Gm29863	predicted gene, 29863	24961	0.18
chr14_60636670_60636838	0.43	Spata13	spermatogenesis associated 13	1999	0.38
chr5_62037605_62037780	0.43	Gm42430	predicted gene 42430	33472	0.23
chr15_90400394_90400702	0.41	Gm36480	predicted gene, 36480	46842	0.18
chr15_54923012_54923175	0.41	Enpp2	ectonucleotide pyrophosphatase/phosphodiesterase 2	480	0.81
chr11_83271635_83271942	0.41	Gm23444	predicted gene, 23444	290	0.8
chr8_94217878_94218059	0.40	Nup93	nucleoporin 93	3362	0.14
chr2_67957572_67957902	0.40	Gm37964	predicted gene, 37964	59141	0.14
chr11_70748249_70748424	0.39	Gm12320	predicted gene 12320	6815	0.09
chr14_74733504_74733933	0.39	Esd	esterase D/formylglutathione hydrolase	1334	0.47
chr2_119318398_119318585	0.38	Gm14207	predicted gene 14207	7052	0.12
chr6_73513110_73513275	0.38	Gm4374	predicted gene 4374	16046	0.19
chr7_84135967_84136134	0.38	Abhd17c	abhydrolase domain containing 17C	11765	0.15
chr9_80777245_80777426	0.38	Gm27224	predicted gene 27224	25316	0.22
chr10_34136560_34136736	0.37	Calhm6	calcium homeostasis modulator family member 6	8664	0.13
chr9_110573946_110574097	0.37	Setd2	SET domain containing 2	137	0.94
chr16_24223745_24224269	0.37	Gm31814	predicted gene, 31814	7483	0.23
chr7_49765686_49765845	0.37	Htatip2	HIV-1 Tat interactive protein 2	6612	0.22
chr11_109734187_109734610	0.37	Fam20a	family with sequence similarity 20, member A	12119	0.17
chr1_95590205_95590368	0.36	Gm37642	predicted gene, 37642	58222	0.13
chr10_84055512_84055676	0.36	Gm37908	predicted gene, 37908	6164	0.21
chr9_53315738_53315899	0.36	Exph5	exophilin 5	14148	0.18
chr8_117720839_117721024	0.36	Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	5	0.97
chr6_92922025_92922180	0.36	9530026P05Rik	RIKEN cDNA 9530026P05 gene	18227	0.19
chr7_98537643_98537832	0.36	A630091E08Rik	RIKEN cDNA A630091E08 gene	25253	0.12
chr7_126230828_126230994	0.35	Gm44703	predicted gene 44703	11716	0.12
chr11_87735822_87735981	0.35	Supt4a	SPT4A, DSIF elongation factor subunit	1651	0.19
chr16_93325022_93325192	0.34	1810053B23Rik	RIKEN cDNA 1810053B23 gene	28082	0.17
chr10_61137486_61137750	0.33	Sgpl1	sphingosine phosphate lyase 1	9280	0.15
chr16_33837321_33837485	0.32	Itgb5	integrin beta 5	7726	0.17
chr12_103820890_103821429	0.32	Gm8893	predicted gene 8893	1084	0.34
chr16_96943868_96944022	0.31	Gm32432	predicted gene, 32432	25188	0.26
chr13_37638048_37638218	0.30	Gm40916	predicted gene, 40916	10103	0.12
chr15_82788288_82788464	0.30	Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	5846	0.1
chr6_31453844_31454029	0.29	Mkln1	muskelin 1, intracellular mediator containing kelch motifs	14184	0.19
chr8_122318051_122318212	0.29	Zfpm1	zinc finger protein, multitype 1	10811	0.13
chr2_3579492_3579678	0.29	Fam107b	family with sequence similarity 107, member B	9097	0.15
chr11_29532358_29532531	0.28	Mtif2	mitochondrial translational initiation factor 2	846	0.45
chr13_45262109_45262392	0.28	Gm34466	predicted gene, 34466	5461	0.23
chr18_4827364_4827665	0.28	Gm10556	predicted gene 10556	15028	0.25
chr2_22587937_22588311	0.27	Gm13341	predicted gene 13341	162	0.91
chr7_123125696_123126050	0.27	Tnrc6a	trinucleotide repeat containing 6a	1617	0.43
chr3_121904528_121904954	0.27	Gm42593	predicted gene 42593	41899	0.12
chr1_88386138_88386312	0.27	Spp2	secreted phosphoprotein 2	20736	0.14
chr3_155090080_155090231	0.27	Fpgt	fucose-1-phosphate guanylyltransferase	364	0.84
chr11_53418376_53418584	0.27	Leap2	liver-expressed antimicrobial peptide 2	4690	0.09
chr18_60748821_60749236	0.26	Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	378	0.77
chr1_72809182_72809347	0.26	Igfbp2	insulin-like growth factor binding protein 2	15239	0.21
chrX_168959751_168959918	0.26	Arhgap6	Rho GTPase activating protein 6	76777	0.11
chr15_46625156_46625324	0.26	4930548G14Rik	RIKEN cDNA 4930548G14 gene	216	0.97
chr14_56746132_56746283	0.26	Pspc1	paraspeckle protein 1	15660	0.12
chr15_82668190_82668753	0.25	Cyp2d35-ps	cytochrome P450, family 2, subfamily d, member 35, pseudogene	13760	0.07
chr15_11394872_11395043	0.25	Tars	threonyl-tRNA synthetase	2687	0.35
chr16_32728387_32728559	0.25	Gm9556	predicted gene 9556	1807	0.27
chr16_29988549_29988737	0.25	Gm1968	predicted gene 1968	9459	0.16
chr6_128538055_128538238	0.25	A2ml1	alpha-2-macroglobulin like 1	5348	0.1
chr14_25751185_25751350	0.25	Zcchc24	zinc finger, CCHC domain containing 24	17772	0.14
chr17_48959982_48960147	0.25	Lrfn2	leucine rich repeat and fibronectin type III domain containing 2	27685	0.23
chr16_24370710_24370861	0.25	Gm41434	predicted gene, 41434	553	0.74
chr7_80340519_80340853	0.25	Unc45a	unc-45 myosin chaperone A	467	0.64
chr12_3912062_3912221	0.25	Dnmt3a	DNA methyltransferase 3A	5325	0.17
chr6_119139630_119139800	0.24	Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	31142	0.19
chr5_130044523_130044702	0.24	Crcp	calcitonin gene-related peptide-receptor component protein	2408	0.2
chr9_48618198_48618386	0.24	Nnmt	nicotinamide N-methyltransferase	13139	0.24
chr2_156175837_156176038	0.24	Rbm39	RNA binding motif protein 39	1446	0.28
chr4_26470101_26470279	0.24	Gm11903	predicted gene 11903	27729	0.19
chr15_25069819_25069985	0.24	Gm2824	predicted gene 2824	42544	0.15
chrX_101953397_101953559	0.24	Nhsl2	NHS-like 2	8319	0.18
chr19_5810333_5810765	0.24	Malat1	metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)	7877	0.08
chr16_21474778_21474944	0.24	Vps8	VPS8 CORVET complex subunit	4674	0.3
chr19_41302182_41302348	0.23	Tm9sf3	transmembrane 9 superfamily member 3	38268	0.17
chr10_110707462_110707627	0.23	E2f7	E2F transcription factor 7	37895	0.16
chr4_141513828_141514048	0.23	Spen	spen family transcription repressor	2971	0.19
chr18_74624820_74624979	0.23	Myo5b	myosin VB	8278	0.25
chr11_102742268_102742437	0.23	Gm16342	predicted gene 16342	9947	0.11
chr11_22443828_22443986	0.23	Gm12050	predicted gene 12050	4132	0.24
chr15_59373722_59374046	0.23	Washc5	WASH complex subunit 5	283	0.57
chr14_51063014_51063572	0.23	Rnase12	ribonuclease, RNase A family, 12 (non-active)	5632	0.09
chr18_11858447_11858616	0.22	Cables1	CDK5 and Abl enzyme substrate 1	14231	0.16
chr3_65660431_65660599	0.22	Mir8120	microRNA 8120	1227	0.38
chr15_63364555_63364706	0.22	Gm41335	predicted gene, 41335	7611	0.27
chr15_89477372_89477550	0.22	Arsa	arylsulfatase A	36	0.77
chr13_58058115_58058280	0.22	Mir874	microRNA 874	34997	0.13
chr14_20830071_20830269	0.22	Plau	plasminogen activator, urokinase	6490	0.15
chr16_22683678_22683832	0.22	Gm8118	predicted gene 8118	2439	0.27
chr10_127937077_127937501	0.21	Gm15900	predicted gene 15900	11271	0.09
chr13_69583732_69583897	0.21	Srd5a1	steroid 5 alpha-reductase 1	11015	0.12
chr17_51852545_51852696	0.21	Gm37266	predicted gene, 37266	2381	0.17
chr1_160730069_160730244	0.21	Gm38329	predicted gene, 38329	1996	0.22
chr3_97631636_97631799	0.21	Fmo5	flavin containing monooxygenase 5	2834	0.19
chr18_46630413_46630795	0.21	Gm3734	predicted gene 3734	203	0.92
chr4_61777961_61778274	0.21	Mup19	major urinary protein 19	4107	0.15
chr8_103468201_103468434	0.21	Gm45277	predicted gene 45277	95306	0.08
chr1_15118618_15118800	0.21	Gm26345	predicted gene, 26345	99550	0.08
chr9_45030162_45030366	0.21	Mpzl2	myelin protein zero-like 2	9535	0.08
chr5_70735708_70735881	0.20	Gabrg1	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	106410	0.07
chr8_33885103_33885396	0.20	Gm26978	predicted gene, 26978	498	0.78
chr2_48539799_48539950	0.20	Gm13481	predicted gene 13481	82629	0.1
chr3_95653729_95653883	0.20	Mcl1	myeloid cell leukemia sequence 1	4982	0.11
chr9_116947417_116947569	0.20	Gm18489	predicted gene, 18489	111665	0.07
chr15_66074244_66074502	0.20	Gm27153	predicted gene 27153	179	0.96
chr4_3829069_3829220	0.20	Gm24016	predicted gene, 24016	6002	0.13
chr4_32607361_32607706	0.20	Gm11933	predicted gene 11933	3818	0.16
chr11_85618066_85618217	0.20	Bcas3	breast carcinoma amplified sequence 3	22563	0.21
chr5_87087250_87087541	0.20	Ugt2b36	UDP glucuronosyltransferase 2 family, polypeptide B36	3762	0.14
chr10_94080899_94081055	0.20	Fgd6	FYVE, RhoGEF and PH domain containing 6	8435	0.13
chr8_112018421_112018578	0.20	Gm6793	predicted gene 6793	3491	0.17
chr15_62067048_62067348	0.20	Pvt1	Pvt1 oncogene	27941	0.22
chr2_168955956_168956111	0.19	Zfp64	zinc finger protein 64	446	0.81
chr2_115093304_115093458	0.19	Gm28493	predicted gene 28493	42169	0.17
chr7_19797036_19797215	0.19	Cblc	Casitas B-lineage lymphoma c	316	0.74
chr11_112720588_112720957	0.19	BC006965	cDNA sequence BC006965	9409	0.26
chr4_104530164_104530485	0.19	Dab1	disabled 1	18251	0.29
chr4_60497810_60497972	0.19	Mup1	major urinary protein 1	1441	0.3
chr5_139338482_139338648	0.19	Cox19	cytochrome c oxidase assembly protein 19	1010	0.41
chr17_13802909_13803139	0.19	Tcte2	t-complex-associated testis expressed 2	41199	0.11
chr11_117242878_117243030	0.18	Septin9	septin 9	10669	0.18
chr9_21799040_21799201	0.18	Kank2	KN motif and ankyrin repeat domains 2	376	0.76
chr11_62568400_62568605	0.18	Gm12280	predicted gene 12280	2119	0.14
chr1_24615703_24615868	0.18	Gm28661	predicted gene 28661	220	0.62
chr7_140748467_140748790	0.18	Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	15111	0.09
chr8_119824884_119825204	0.18	Cotl1	coactosin-like 1 (Dictyostelium)	2327	0.27
chr2_169634592_169634925	0.18	Tshz2	teashirt zinc finger family member 2	1082	0.55
chr4_60135275_60135767	0.18	Mup2	major urinary protein 2	4336	0.2
chr16_77329783_77330099	0.18	Mir99ahg	Mir99a and Mirlet7c-1 host gene (non-protein coding)	437	0.81
chr11_83743719_83744166	0.18	Wfdc21	WAP four-disulfide core domain 21	2998	0.13
chr9_54738475_54738626	0.17	Wdr61	WD repeat domain 61	4031	0.17
chr3_125754703_125754854	0.17	Ndst4	N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4	44692	0.2
chr12_86324285_86324473	0.17	4732487G21Rik	RIKEN cDNA 4732487G21 gene	18373	0.17
chr3_133765600_133766533	0.17	Gm6135	prediticted gene 6135	25438	0.2
chr1_167381535_167381702	0.17	Mgst3	microsomal glutathione S-transferase 3	12223	0.14
chr19_23142829_23142995	0.17	Klf9	Kruppel-like factor 9	732	0.62
chr17_43418663_43418829	0.17	Adgrf5	adhesion G protein-coupled receptor F5	8266	0.22
chr10_78266639_78266790	0.17	Gm47976	predicted gene, 47976	639	0.52
chr15_10901196_10901355	0.17	Gm29742	predicted gene, 29742	16162	0.17
chr1_86630817_86630968	0.17	Gm22955	predicted gene, 22955	6716	0.13
chr17_88050390_88050623	0.17	Fbxo11	F-box protein 11	14381	0.19
chr8_126615919_126616193	0.17	Irf2bp2	interferon regulatory factor 2 binding protein 2	22070	0.21
chr8_115719843_115720129	0.17	Maf	avian musculoaponeurotic fibrosarcoma oncogene homolog	12192	0.23
chr10_83244234_83244393	0.17	Slc41a2	solute carrier family 41, member 2	60062	0.11
chr1_179836517_179836707	0.17	Ahctf1	AT hook containing transcription factor 1	32932	0.16
chr16_23337603_23337782	0.17	St6gal1	beta galactoside alpha 2,6 sialyltransferase 1	47222	0.11
chr16_93808092_93808456	0.17	Dop1b	DOP1 leucine zipper like protein B	1160	0.4
chr2_135693224_135693399	0.17	Gm14211	predicted gene 14211	157	0.96
chr8_10939998_10940171	0.17	Gm44955	predicted gene 44955	7806	0.11
chr2_75563293_75563456	0.17	Gm13655	predicted gene 13655	70008	0.08
chr14_73253316_73253480	0.16	Rb1	RB transcriptional corepressor 1	10923	0.17
chr9_77927047_77927209	0.16	Elovl5	ELOVL family member 5, elongation of long chain fatty acids (yeast)	5196	0.17
chr2_91794631_91794782	0.16	Ambra1	autophagy/beclin 1 regulator 1	16962	0.17
chr11_120624046_120624203	0.16	Mir6936	microRNA 6936	752	0.26
chr18_35704126_35704282	0.16	1700066B19Rik	RIKEN cDNA 1700066B19 gene	979	0.28
chr7_81230207_81230362	0.16	Gm7180	predicted pseudogene 7180	7410	0.16
chr4_60737134_60737406	0.16	Mup12	major urinary protein 12	4056	0.21
chr3_104541230_104541625	0.16	Lrig2	leucine-rich repeats and immunoglobulin-like domains 2	29509	0.1
chr10_99555138_99555310	0.16	Gm48085	predicted gene, 48085	17155	0.18
chr13_10445800_10445958	0.16	Gm47407	predicted gene, 47407	71808	0.1
chr8_36712891_36713250	0.16	Dlc1	deleted in liver cancer 1	19984	0.26
chr10_63373741_63373935	0.16	Sirt1	sirtuin 1	7866	0.13
chr7_49475399_49475550	0.16	Gm38059	predicted gene, 38059	5762	0.25
chr11_88059290_88059457	0.16	Gm15892	predicted gene 15892	307	0.84
chr3_85821987_85822152	0.16	Fam160a1	family with sequence similarity 160, member A1	4778	0.2
chr4_62087229_62087597	0.16	Mup3	major urinary protein 3	71	0.93
chr5_16316197_16316406	0.16	Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	9684	0.24
chr6_72212736_72212914	0.16	Atoh8	atonal bHLH transcription factor 8	21712	0.14
chr11_102543825_102543998	0.16	Mdk-ps1	midkine pseudogene 1	1791	0.21
chr3_146581553_146581772	0.16	Uox	urate oxidase	11236	0.13
chr9_66285727_66286140	0.16	Dapk2	death-associated protein kinase 2	17559	0.2
chr6_99206656_99206831	0.16	Foxp1	forkhead box P1	41593	0.2
chr1_89516107_89516298	0.16	Gm37297	predicted gene, 37297	32764	0.15
chr8_128387567_128387718	0.16	Nrp1	neuropilin 1	28245	0.19
chr5_102481207_102481593	0.16	Arhgap24	Rho GTPase activating protein 24	9	0.97
chr17_28279592_28279743	0.15	Ppard	peroxisome proliferator activator receptor delta	7548	0.11
chr4_60066252_60066431	0.15	Mup7	major urinary protein 7	4070	0.21
chr2_174672606_174672877	0.15	Zfp831	zinc finger protein 831	29207	0.18
chr9_20803282_20803448	0.15	Col5a3	collagen, type V, alpha 3	11702	0.11
chr7_80024172_80024601	0.15	Zfp710	zinc finger protein 710	428	0.76
chr5_145191503_145191838	0.15	Atp5j2	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2	78	0.94
chr11_113610401_113610567	0.15	Sstr2	somatostatin receptor 2	8858	0.17

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2e1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.1	0.3	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
0.1	0.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.4	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	0.2	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.0	0.1	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.2	GO:0046292	formaldehyde metabolic process(GO:0046292)
0.0	0.2	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.2	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0002125	maternal aggressive behavior(GO:0002125)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.5	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.1	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.1	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0	0.1	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0	0.3	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.1	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.1	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.0	0.1	GO:0032439	endosome localization(GO:0032439)
0.0	0.1	GO:0035973	aggrephagy(GO:0035973)
0.0	0.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	0.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.0	GO:0060375	regulation of mast cell differentiation(GO:0060375)
0.0	0.1	GO:0071873	response to norepinephrine(GO:0071873)
0.0	0.1	GO:0060018	astrocyte fate commitment(GO:0060018)
0.0	0.1	GO:0031508	pericentric heterochromatin assembly(GO:0031508)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.0	0.0	GO:0036023	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0	0.1	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0	0.1	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.0	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.0	0.0	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0	0.0	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.0	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.1	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.1	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.0	0.0	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.0	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0	0.0	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.1	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636)
0.0	0.0	GO:0052203	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.1	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.1	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	0.0	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0	0.1	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0	0.0	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.1	GO:0014745	negative regulation of muscle adaptation(GO:0014745)
0.0	0.0	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.0	0.0	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.1	GO:0098911	regulation of ventricular cardiac muscle cell action potential(GO:0098911)
0.0	0.0	GO:0010273	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0	0.0	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0	0.0	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.0	0.0	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.0	0.0	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.0	0.0	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.0	0.0	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.0	GO:0061626	pharyngeal arch artery morphogenesis(GO:0061626)
0.0	0.0	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.1	GO:0033263	CORVET complex(GO:0033263)
0.1	GO:0005726	perichromatin fibrils(GO:0005726)
0.1	GO:0016589	NURF complex(GO:0016589)
0.0	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.1	GO:0071986	Ragulator complex(GO:0071986)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.4	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.3	GO:0008390	testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.1	0.3	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.4	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.6	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.5	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0	0.1	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.1	GO:0043338	CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.0	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.0	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.0	GO:0070698	type I activin receptor binding(GO:0070698)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.0	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0	0.0	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.1	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.5	PID RAC1 REG PATHWAY	Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis