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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Nr2e1

Z-value: 0.89

Motif logo

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Transcription factors associated with Nr2e1

Gene Symbol Gene ID Gene Info
Nr2e1
ENSMUSG00000019803.5 nuclear receptor subfamily 2, group E, member 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr10_42538714_42538885Nr2e1300290.1457050.805.4e-02Click!

Activity of the Nr2e1 motif across conditions

Conditions sorted by the z-value of the Nr2e1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_146107597_146107748 1.37 Cyp3a59
 cytochrome P450, family 3, subfamily a, polypeptide 59
 28405
 0.11
chr5_118292276_118292427 0.98 Gm25076
 predicted gene, 25076
 25902
 0.16
chr5_145982849_145983558 0.94 Cyp3a25
 cytochrome P450, family 3, subfamily a, polypeptide 25
 8440
 0.13
chr3_88628445_88628599 0.93 Arhgef2
 rho/rac guanine nucleotide exchange factor (GEF) 2
 920
 0.37
chr10_115348229_115348396 0.83 Tmem19
 transmembrane protein 19
 752
 0.58
chr10_122408778_122408952 0.82 Gm36041
 predicted gene, 36041
 21973
 0.18
chr9_78022696_78022864 0.74 Gm47829
 predicted gene, 47829
 5165
 0.12
chr14_19839858_19840045 0.61 D14Ertd670e
 DNA segment, Chr 14, ERATO Doi 670, expressed
 1026
 0.48
chr8_73114845_73115014 0.60 Large1
 LARGE xylosyl- and glucuronyltransferase 1
 16016
 0.24
chr10_28078586_28078966 0.59 Ptprk
 protein tyrosine phosphatase, receptor type, K
 3766
 0.28
chr4_118129721_118129877 0.58 St3gal3
 ST3 beta-galactoside alpha-2,3-sialyltransferase 3
 5083
 0.18
chr11_107109633_107109941 0.58 Bptf
 bromodomain PHD finger transcription factor
 22135
 0.14
chr15_8968437_8968609 0.56 Ranbp3l
 RAN binding protein 3-like
 97
 0.97
chr5_98996002_98996174 0.54 Gm3470
 predicted gene 3470
 26134
 0.2
chr3_101953485_101953642 0.49 Slc22a15
 solute carrier family 22 (organic anion/cation transporter), member 15
 29110
 0.17
chr17_24797110_24797261 0.48 Meiob
 meiosis specific with OB domains
 7104
 0.09
chr7_101491003_101491309 0.46 Pde2a
 phosphodiesterase 2A, cGMP-stimulated
 9871
 0.14
chr19_41838995_41839153 0.46 Frat2
 frequently rearranged in advanced T cell lymphomas 2
 9058
 0.14
chr12_84939464_84939615 0.45 Arel1
 apoptosis resistant E3 ubiquitin protein ligase 1
 3839
 0.15
chr9_66327050_66327224 0.45 Herc1
 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
 23313
 0.17
chr11_50733265_50733435 0.45 Gm12200
 predicted gene 12200
 7806
 0.16
chr6_30286706_30286895 0.44 Ube2h
 ubiquitin-conjugating enzyme E2H
 17722
 0.14
chr19_33094946_33095121 0.44 Gm29863
 predicted gene, 29863
 24961
 0.18
chr14_60636670_60636838 0.43 Spata13
 spermatogenesis associated 13
 1999
 0.38
chr5_62037605_62037780 0.43 Gm42430
 predicted gene 42430
 33472
 0.23
chr15_90400394_90400702 0.41 Gm36480
 predicted gene, 36480
 46842
 0.18
chr15_54923012_54923175 0.41 Enpp2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
 480
 0.81
chr11_83271635_83271942 0.41 Gm23444
 predicted gene, 23444
 290
 0.8
chr8_94217878_94218059 0.40 Nup93
 nucleoporin 93
 3362
 0.14
chr2_67957572_67957902 0.40 Gm37964
 predicted gene, 37964
 59141
 0.14
chr11_70748249_70748424 0.39 Gm12320
 predicted gene 12320
 6815
 0.09
chr14_74733504_74733933 0.39 Esd
 esterase D/formylglutathione hydrolase
 1334
 0.47
chr2_119318398_119318585 0.38 Gm14207
 predicted gene 14207
 7052
 0.12
chr6_73513110_73513275 0.38 Gm4374
 predicted gene 4374
 16046
 0.19
chr7_84135967_84136134 0.38 Abhd17c
 abhydrolase domain containing 17C
 11765
 0.15
chr9_80777245_80777426 0.38 Gm27224
 predicted gene 27224
 25316
 0.22
chr10_34136560_34136736 0.37 Calhm6
 calcium homeostasis modulator family member 6
 8664
 0.13
chr9_110573946_110574097 0.37 Setd2
 SET domain containing 2
 137
 0.94
chr16_24223745_24224269 0.37 Gm31814
 predicted gene, 31814
 7483
 0.23
chr7_49765686_49765845 0.37 Htatip2
 HIV-1 Tat interactive protein 2
 6612
 0.22
chr11_109734187_109734610 0.37 Fam20a
 family with sequence similarity 20, member A
 12119
 0.17
chr1_95590205_95590368 0.36 Gm37642
 predicted gene, 37642
 58222
 0.13
chr10_84055512_84055676 0.36 Gm37908
 predicted gene, 37908
 6164
 0.21
chr9_53315738_53315899 0.36 Exph5
 exophilin 5
 14148
 0.18
chr8_117720839_117721024 0.36 Hsd17b2
 hydroxysteroid (17-beta) dehydrogenase 2
 5
 0.97
chr6_92922025_92922180 0.36 9530026P05Rik
 RIKEN cDNA 9530026P05 gene
 18227
 0.19
chr7_98537643_98537832 0.36 A630091E08Rik
 RIKEN cDNA A630091E08 gene
 25253
 0.12
chr7_126230828_126230994 0.35 Gm44703
 predicted gene 44703
 11716
 0.12
chr11_87735822_87735981 0.35 Supt4a
 SPT4A, DSIF elongation factor subunit
 1651
 0.19
chr16_93325022_93325192 0.34 1810053B23Rik
 RIKEN cDNA 1810053B23 gene
 28082
 0.17
chr10_61137486_61137750 0.33 Sgpl1
 sphingosine phosphate lyase 1
 9280
 0.15
chr16_33837321_33837485 0.32 Itgb5
 integrin beta 5
 7726
 0.17
chr12_103820890_103821429 0.32 Gm8893
 predicted gene 8893
 1084
 0.34
chr16_96943868_96944022 0.31 Gm32432
 predicted gene, 32432
 25188
 0.26
chr13_37638048_37638218 0.30 Gm40916
 predicted gene, 40916
 10103
 0.12
chr15_82788288_82788464 0.30 Cyp2d26
 cytochrome P450, family 2, subfamily d, polypeptide 26
 5846
 0.1
chr6_31453844_31454029 0.29 Mkln1
 muskelin 1, intracellular mediator containing kelch motifs
 14184
 0.19
chr8_122318051_122318212 0.29 Zfpm1
 zinc finger protein, multitype 1
 10811
 0.13
chr2_3579492_3579678 0.29 Fam107b
 family with sequence similarity 107, member B
 9097
 0.15
chr11_29532358_29532531 0.28 Mtif2
 mitochondrial translational initiation factor 2
 846
 0.45
chr13_45262109_45262392 0.28 Gm34466
 predicted gene, 34466
 5461
 0.23
chr18_4827364_4827665 0.28 Gm10556
 predicted gene 10556
 15028
 0.25
chr2_22587937_22588311 0.27 Gm13341
 predicted gene 13341
 162
 0.91
chr7_123125696_123126050 0.27 Tnrc6a
 trinucleotide repeat containing 6a
 1617
 0.43
chr3_121904528_121904954 0.27 Gm42593
 predicted gene 42593
 41899
 0.12
chr1_88386138_88386312 0.27 Spp2
 secreted phosphoprotein 2
 20736
 0.14
chr3_155090080_155090231 0.27 Fpgt
 fucose-1-phosphate guanylyltransferase
 364
 0.84
chr11_53418376_53418584 0.27 Leap2
 liver-expressed antimicrobial peptide 2
 4690
 0.09
chr18_60748821_60749236 0.26 Ndst1
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
 378
 0.77
chr1_72809182_72809347 0.26 Igfbp2
 insulin-like growth factor binding protein 2
 15239
 0.21
chrX_168959751_168959918 0.26 Arhgap6
 Rho GTPase activating protein 6
 76777
 0.11
chr15_46625156_46625324 0.26 4930548G14Rik
 RIKEN cDNA 4930548G14 gene
 216
 0.97
chr14_56746132_56746283 0.26 Pspc1
 paraspeckle protein 1
 15660
 0.12
chr15_82668190_82668753 0.25 Cyp2d35-ps
 cytochrome P450, family 2, subfamily d, member 35, pseudogene
 13760
 0.07
chr15_11394872_11395043 0.25 Tars
 threonyl-tRNA synthetase
 2687
 0.35
chr16_32728387_32728559 0.25 Gm9556
 predicted gene 9556
 1807
 0.27
chr16_29988549_29988737 0.25 Gm1968
 predicted gene 1968
 9459
 0.16
chr6_128538055_128538238 0.25 A2ml1
 alpha-2-macroglobulin like 1
 5348
 0.1
chr14_25751185_25751350 0.25 Zcchc24
 zinc finger, CCHC domain containing 24
 17772
 0.14
chr17_48959982_48960147 0.25 Lrfn2
 leucine rich repeat and fibronectin type III domain containing 2
 27685
 0.23
chr16_24370710_24370861 0.25 Gm41434
 predicted gene, 41434
 553
 0.74
chr7_80340519_80340853 0.25 Unc45a
 unc-45 myosin chaperone A
 467
 0.64
chr12_3912062_3912221 0.25 Dnmt3a
 DNA methyltransferase 3A
 5325
 0.17
chr6_119139630_119139800 0.24 Cacna1c
 calcium channel, voltage-dependent, L type, alpha 1C subunit
 31142
 0.19
chr5_130044523_130044702 0.24 Crcp
 calcitonin gene-related peptide-receptor component protein
 2408
 0.2
chr9_48618198_48618386 0.24 Nnmt
 nicotinamide N-methyltransferase
 13139
 0.24
chr2_156175837_156176038 0.24 Rbm39
 RNA binding motif protein 39
 1446
 0.28
chr4_26470101_26470279 0.24 Gm11903
 predicted gene 11903
 27729
 0.19
chr15_25069819_25069985 0.24 Gm2824
 predicted gene 2824
 42544
 0.15
chrX_101953397_101953559 0.24 Nhsl2
 NHS-like 2
 8319
 0.18
chr19_5810333_5810765 0.24 Malat1
 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
 7877
 0.08
chr16_21474778_21474944 0.24 Vps8
 VPS8 CORVET complex subunit
 4674
 0.3
chr19_41302182_41302348 0.23 Tm9sf3
 transmembrane 9 superfamily member 3
 38268
 0.17
chr10_110707462_110707627 0.23 E2f7
 E2F transcription factor 7
 37895
 0.16
chr4_141513828_141514048 0.23 Spen
 spen family transcription repressor
 2971
 0.19
chr18_74624820_74624979 0.23 Myo5b
 myosin VB
 8278
 0.25
chr11_102742268_102742437 0.23 Gm16342
 predicted gene 16342
 9947
 0.11
chr11_22443828_22443986 0.23 Gm12050
 predicted gene 12050
 4132
 0.24
chr15_59373722_59374046 0.23 Washc5
 WASH complex subunit 5
 283
 0.57
chr14_51063014_51063572 0.23 Rnase12
 ribonuclease, RNase A family, 12 (non-active)
 5632
 0.09
chr18_11858447_11858616 0.22 Cables1
 CDK5 and Abl enzyme substrate 1
 14231
 0.16
chr3_65660431_65660599 0.22 Mir8120
 microRNA 8120
 1227
 0.38
chr15_63364555_63364706 0.22 Gm41335
 predicted gene, 41335
 7611
 0.27
chr15_89477372_89477550 0.22 Arsa
 arylsulfatase A
 36
 0.77
chr13_58058115_58058280 0.22 Mir874
 microRNA 874
 34997
 0.13
chr14_20830071_20830269 0.22 Plau
 plasminogen activator, urokinase
 6490
 0.15
chr16_22683678_22683832 0.22 Gm8118
 predicted gene 8118
 2439
 0.27
chr10_127937077_127937501 0.21 Gm15900
 predicted gene 15900
 11271
 0.09
chr13_69583732_69583897 0.21 Srd5a1
 steroid 5 alpha-reductase 1
 11015
 0.12
chr17_51852545_51852696 0.21 Gm37266
 predicted gene, 37266
 2381
 0.17
chr1_160730069_160730244 0.21 Gm38329
 predicted gene, 38329
 1996
 0.22
chr3_97631636_97631799 0.21 Fmo5
 flavin containing monooxygenase 5
 2834
 0.19
chr18_46630413_46630795 0.21 Gm3734
 predicted gene 3734
 203
 0.92
chr4_61777961_61778274 0.21 Mup19
 major urinary protein 19
 4107
 0.15
chr8_103468201_103468434 0.21 Gm45277
 predicted gene 45277
 95306
 0.08
chr1_15118618_15118800 0.21 Gm26345
 predicted gene, 26345
 99550
 0.08
chr9_45030162_45030366 0.21 Mpzl2
 myelin protein zero-like 2
 9535
 0.08
chr5_70735708_70735881 0.20 Gabrg1
 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
 106410
 0.07
chr8_33885103_33885396 0.20 Gm26978
 predicted gene, 26978
 498
 0.78
chr2_48539799_48539950 0.20 Gm13481
 predicted gene 13481
 82629
 0.1
chr3_95653729_95653883 0.20 Mcl1
 myeloid cell leukemia sequence 1
 4982
 0.11
chr9_116947417_116947569 0.20 Gm18489
 predicted gene, 18489
 111665
 0.07
chr15_66074244_66074502 0.20 Gm27153
 predicted gene 27153
 179
 0.96
chr4_3829069_3829220 0.20 Gm24016
 predicted gene, 24016
 6002
 0.13
chr4_32607361_32607706 0.20 Gm11933
 predicted gene 11933
 3818
 0.16
chr11_85618066_85618217 0.20 Bcas3
 breast carcinoma amplified sequence 3
 22563
 0.21
chr5_87087250_87087541 0.20 Ugt2b36
 UDP glucuronosyltransferase 2 family, polypeptide B36
 3762
 0.14
chr10_94080899_94081055 0.20 Fgd6
 FYVE, RhoGEF and PH domain containing 6
 8435
 0.13
chr8_112018421_112018578 0.20 Gm6793
 predicted gene 6793
 3491
 0.17
chr15_62067048_62067348 0.20 Pvt1
 Pvt1 oncogene
 27941
 0.22
chr2_168955956_168956111 0.19 Zfp64
 zinc finger protein 64
 446
 0.81
chr2_115093304_115093458 0.19 Gm28493
 predicted gene 28493
 42169
 0.17
chr7_19797036_19797215 0.19 Cblc
 Casitas B-lineage lymphoma c
 316
 0.74
chr11_112720588_112720957 0.19 BC006965
 cDNA sequence BC006965
 9409
 0.26
chr4_104530164_104530485 0.19 Dab1
 disabled 1
 18251
 0.29
chr4_60497810_60497972 0.19 Mup1
 major urinary protein 1
 1441
 0.3
chr5_139338482_139338648 0.19 Cox19
 cytochrome c oxidase assembly protein 19
 1010
 0.41
chr17_13802909_13803139 0.19 Tcte2
 t-complex-associated testis expressed 2
 41199
 0.11
chr11_117242878_117243030 0.18 Septin9
 septin 9
 10669
 0.18
chr9_21799040_21799201 0.18 Kank2
 KN motif and ankyrin repeat domains 2
 376
 0.76
chr11_62568400_62568605 0.18 Gm12280
 predicted gene 12280
 2119
 0.14
chr1_24615703_24615868 0.18 Gm28661
 predicted gene 28661
 220
 0.62
chr7_140748467_140748790 0.18 Cyp2e1
 cytochrome P450, family 2, subfamily e, polypeptide 1
 15111
 0.09
chr8_119824884_119825204 0.18 Cotl1
 coactosin-like 1 (Dictyostelium)
 2327
 0.27
chr2_169634592_169634925 0.18 Tshz2
 teashirt zinc finger family member 2
 1082
 0.55
chr4_60135275_60135767 0.18 Mup2
 major urinary protein 2
 4336
 0.2
chr16_77329783_77330099 0.18 Mir99ahg
 Mir99a and Mirlet7c-1 host gene (non-protein coding)
 437
 0.81
chr11_83743719_83744166 0.18 Wfdc21
 WAP four-disulfide core domain 21
 2998
 0.13
chr9_54738475_54738626 0.17 Wdr61
 WD repeat domain 61
 4031
 0.17
chr3_125754703_125754854 0.17 Ndst4
 N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
 44692
 0.2
chr12_86324285_86324473 0.17 4732487G21Rik
 RIKEN cDNA 4732487G21 gene
 18373
 0.17
chr3_133765600_133766533 0.17 Gm6135
 prediticted gene 6135
 25438
 0.2
chr1_167381535_167381702 0.17 Mgst3
 microsomal glutathione S-transferase 3
 12223
 0.14
chr19_23142829_23142995 0.17 Klf9
 Kruppel-like factor 9
 732
 0.62
chr17_43418663_43418829 0.17 Adgrf5
 adhesion G protein-coupled receptor F5
 8266
 0.22
chr10_78266639_78266790 0.17 Gm47976
 predicted gene, 47976
 639
 0.52
chr15_10901196_10901355 0.17 Gm29742
 predicted gene, 29742
 16162
 0.17
chr1_86630817_86630968 0.17 Gm22955
 predicted gene, 22955
 6716
 0.13
chr17_88050390_88050623 0.17 Fbxo11
 F-box protein 11
 14381
 0.19
chr8_126615919_126616193 0.17 Irf2bp2
 interferon regulatory factor 2 binding protein 2
 22070
 0.21
chr8_115719843_115720129 0.17 Maf
 avian musculoaponeurotic fibrosarcoma oncogene homolog
 12192
 0.23
chr10_83244234_83244393 0.17 Slc41a2
 solute carrier family 41, member 2
 60062
 0.11
chr1_179836517_179836707 0.17 Ahctf1
 AT hook containing transcription factor 1
 32932
 0.16
chr16_23337603_23337782 0.17 St6gal1
 beta galactoside alpha 2,6 sialyltransferase 1
 47222
 0.11
chr16_93808092_93808456 0.17 Dop1b
 DOP1 leucine zipper like protein B
 1160
 0.4
chr2_135693224_135693399 0.17 Gm14211
 predicted gene 14211
 157
 0.96
chr8_10939998_10940171 0.17 Gm44955
 predicted gene 44955
 7806
 0.11
chr2_75563293_75563456 0.17 Gm13655
 predicted gene 13655
 70008
 0.08
chr14_73253316_73253480 0.16 Rb1
 RB transcriptional corepressor 1
 10923
 0.17
chr9_77927047_77927209 0.16 Elovl5
 ELOVL family member 5, elongation of long chain fatty acids (yeast)
 5196
 0.17
chr2_91794631_91794782 0.16 Ambra1
 autophagy/beclin 1 regulator 1
 16962
 0.17
chr11_120624046_120624203 0.16 Mir6936
 microRNA 6936
 752
 0.26
chr18_35704126_35704282 0.16 1700066B19Rik
 RIKEN cDNA 1700066B19 gene
 979
 0.28
chr7_81230207_81230362 0.16 Gm7180
 predicted pseudogene 7180
 7410
 0.16
chr4_60737134_60737406 0.16 Mup12
 major urinary protein 12
 4056
 0.21
chr3_104541230_104541625 0.16 Lrig2
 leucine-rich repeats and immunoglobulin-like domains 2
 29509
 0.1
chr10_99555138_99555310 0.16 Gm48085
 predicted gene, 48085
 17155
 0.18
chr13_10445800_10445958 0.16 Gm47407
 predicted gene, 47407
 71808
 0.1
chr8_36712891_36713250 0.16 Dlc1
 deleted in liver cancer 1
 19984
 0.26
chr10_63373741_63373935 0.16 Sirt1
 sirtuin 1
 7866
 0.13
chr7_49475399_49475550 0.16 Gm38059
 predicted gene, 38059
 5762
 0.25
chr11_88059290_88059457 0.16 Gm15892
 predicted gene 15892
 307
 0.84
chr3_85821987_85822152 0.16 Fam160a1
 family with sequence similarity 160, member A1
 4778
 0.2
chr4_62087229_62087597 0.16 Mup3
 major urinary protein 3
 71
 0.93
chr5_16316197_16316406 0.16 Cacna2d1
 calcium channel, voltage-dependent, alpha2/delta subunit 1
 9684
 0.24
chr6_72212736_72212914 0.16 Atoh8
 atonal bHLH transcription factor 8
 21712
 0.14
chr11_102543825_102543998 0.16 Mdk-ps1
 midkine pseudogene 1
 1791
 0.21
chr3_146581553_146581772 0.16 Uox
 urate oxidase
 11236
 0.13
chr9_66285727_66286140 0.16 Dapk2
 death-associated protein kinase 2
 17559
 0.2
chr6_99206656_99206831 0.16 Foxp1
 forkhead box P1
 41593
 0.2
chr1_89516107_89516298 0.16 Gm37297
 predicted gene, 37297
 32764
 0.15
chr8_128387567_128387718 0.16 Nrp1
 neuropilin 1
 28245
 0.19
chr5_102481207_102481593 0.16 Arhgap24
 Rho GTPase activating protein 24
 9
 0.97
chr17_28279592_28279743 0.15 Ppard
 peroxisome proliferator activator receptor delta
 7548
 0.11
chr4_60066252_60066431 0.15 Mup7
 major urinary protein 7
 4070
 0.21
chr2_174672606_174672877 0.15 Zfp831
 zinc finger protein 831
 29207
 0.18
chr9_20803282_20803448 0.15 Col5a3
 collagen, type V, alpha 3
 11702
 0.11
chr7_80024172_80024601 0.15 Zfp710
 zinc finger protein 710
 428
 0.76
chr5_145191503_145191838 0.15 Atp5j2
 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2
 78
 0.94
chr11_113610401_113610567 0.15 Sstr2
 somatostatin receptor 2
 8858
 0.17

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2e1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.1 0.3 GO:0071225 cellular response to muramyl dipeptide(GO:0071225)
0.1 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.2 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 0.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:0046499 S-adenosylmethioninamine metabolic process(GO:0046499)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.0 GO:0060375 regulation of mast cell differentiation(GO:0060375)
0.0 0.1 GO:0071873 response to norepinephrine(GO:0071873)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.0 0.0 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.0 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.0 0.0 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0 0.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.0 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.0 0.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.0 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.0 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.0 GO:0052203 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.0 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.0 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0014745 negative regulation of muscle adaptation(GO:0014745)
0.0 0.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.0 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0098911 regulation of ventricular cardiac muscle cell action potential(GO:0098911)
0.0 0.0 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.0 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.0 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.0 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0061684 chaperone-mediated autophagy(GO:0061684)
0.0 0.0 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.0 GO:0061626 pharyngeal arch artery morphogenesis(GO:0061626)
0.0 0.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.0 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.0 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.3 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.1 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.4 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0043338 CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.0 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.0 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.0 GO:0034584 piRNA binding(GO:0034584)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis