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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Nr3c2

Z-value: 6.34

Motif logo

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Transcription factors associated with Nr3c2

Gene Symbol Gene ID Gene Info
ENSMUSG00000031618.7 Nr3c2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

GenePromoterDistanceAssociation probabilityPearson corr. coef.P-valuePlot
Nr3c2chr8_76935013_76935165268170.1919900.953.6e-03Click!
Nr3c2chr8_76902033_769022221610.941199-0.944.9e-03Click!
Nr3c2chr8_77057050_77057484707460.1069130.945.7e-03Click!
Nr3c2chr8_76902272_7690243040.973850-0.911.2e-02Click!
Nr3c2chr8_76983976_76984150757910.0989610.911.2e-02Click!

Activity of the Nr3c2 motif across conditions

Conditions sorted by the z-value of the Nr3c2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_25884401_25884651 11.57 Gm6434
predicted gene 6434
2137
0.18
chr1_162891903_162892071 10.98 Fmo2
flavin containing monooxygenase 2
5472
0.19
chr18_54250751_54250951 10.58 Redrum
Redrum, erythroid developmental long intergenic non-protein coding transcript
171444
0.03
chr2_160805166_160805505 10.45 Gm11447
predicted gene 11447
40278
0.11
chr1_174765547_174765725 10.33 Fmn2
formin 2
51310
0.17
chr6_149359539_149359690 10.18 Gm15784
predicted gene 15784
2072
0.23
chr13_82200839_82201017 9.67 Gm48155
predicted gene, 48155
111171
0.07
chr18_84054624_84054776 8.55 Tshz1
teashirt zinc finger family member 1
30375
0.14
chr19_12708659_12708815 8.55 Gm15962
predicted gene 15962
12466
0.09
chr12_83544904_83545068 8.50 Zfyve1
zinc finger, FYVE domain containing 1
6719
0.16
chr1_55509753_55509917 7.68 Gm37382
predicted gene, 37382
49625
0.12
chr7_126932811_126932965 7.23 Kctd13
potassium channel tetramerisation domain containing 13
2967
0.08
chr17_28420256_28420436 7.10 Fkbp5
FK506 binding protein 5
1819
0.21
chr14_88428338_88428489 6.96 Gm48930
predicted gene, 48930
12388
0.18
chr16_42998828_42999221 6.94 Ndufs5-ps
NADH:ubiquinone oxidoreductase core subunit S5, pseudogene
43393
0.16
chr17_28442321_28442494 6.89 Fkbp5
FK506 binding protein 5
685
0.52
chr5_87499011_87499178 6.78 Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
8223
0.12
chr11_16589377_16589551 6.34 Gm12663
predicted gene 12663
46602
0.12
chr16_93335454_93335612 6.29 1810053B23Rik
RIKEN cDNA 1810053B23 gene
17656
0.18
chr4_141176604_141176782 6.21 Fbxo42
F-box protein 42
28771
0.09
chr5_77102713_77103043 6.17 Hopx
HOP homeobox
7601
0.13
chr6_141432376_141432556 6.09 Gm43958
predicted gene, 43958
9894
0.26
chr4_141863008_141863177 5.99 Efhd2
EF hand domain containing 2
11828
0.1
chr14_76149595_76149834 5.97 Nufip1
nuclear fragile X mental retardation protein interacting protein 1
38823
0.15
chr8_105122845_105122996 5.79 Ces4a
carboxylesterase 4A
8880
0.1
chr4_122958854_122959026 5.69 Mfsd2a
major facilitator superfamily domain containing 2A
1050
0.41
chr7_98354672_98354893 5.64 Tsku
tsukushi, small leucine rich proteoglycan
5297
0.19
chr10_66930552_66930719 5.61 Gm26576
predicted gene, 26576
10333
0.16
chr16_36933903_36934054 5.58 Hcls1
hematopoietic cell specific Lyn substrate 1
1005
0.38
chr6_115238722_115238899 5.50 Syn2
synapsin II
184
0.94
chr12_80821404_80821588 5.45 Susd6
sushi domain containing 6
30937
0.11
chr9_106235574_106235761 5.36 Alas1
aminolevulinic acid synthase 1
1417
0.25
chr11_17169395_17169562 5.36 Ppp3r1
protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
10215
0.17
chr15_7039229_7039416 5.31 Gm38282
predicted gene, 38282
43285
0.17
chr5_51537135_51537286 5.27 Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
16661
0.16
chr6_108093306_108093738 4.94 Setmar
SET domain without mariner transposase fusion
28460
0.17
chr1_193926856_193927030 4.82 Gm21362
predicted gene, 21362
59934
0.16
chr17_81385422_81385814 4.78 Gm50044
predicted gene, 50044
14785
0.24
chr4_19632141_19632303 4.61 Gm12353
predicted gene 12353
26771
0.17
chr9_74328406_74328599 4.60 Gm24141
predicted gene, 24141
34108
0.17
chr15_84639552_84639765 4.51 Prr5
proline rich 5 (renal)
29962
0.16
chr19_46908820_46909200 4.51 Nt5c2
5'-nucleotidase, cytosolic II
565
0.74
chr11_38774641_38774792 4.51 Gm23520
predicted gene, 23520
23561
0.29
chr8_105546777_105546967 4.47 Atp6v0d1
ATPase, H+ transporting, lysosomal V0 subunit D1
7396
0.09
chr9_44078939_44079310 4.39 Usp2
ubiquitin specific peptidase 2
5815
0.08
chr3_105758672_105758857 4.36 Rap1a
RAS-related protein 1a
8436
0.11
chr17_28761138_28761314 4.36 Mapk13
mitogen-activated protein kinase 13
8071
0.12
chr14_20148641_20148813 4.32 Kcnk5
potassium channel, subfamily K, member 5
3433
0.19
chr1_82188640_82188847 4.19 Gm9747
predicted gene 9747
44369
0.14
chr1_21258115_21258471 4.18 Gsta3
glutathione S-transferase, alpha 3
4772
0.12
chr1_21324523_21325070 4.10 Gm21909
predicted gene, 21909
8476
0.1
chr1_88166599_88166770 4.06 Ugt1a5
UDP glucuronosyltransferase 1 family, polypeptide A5
672
0.4
chr2_26481863_26482061 3.88 Notch1
notch 1
11464
0.1
chr13_101812017_101812199 3.80 Gm19108
predicted gene, 19108
30198
0.15
chr1_74047431_74047619 3.78 Tns1
tensin 1
10368
0.21
chr8_34975223_34975418 3.76 Gm34368
predicted gene, 34368
4554
0.19
chr10_77440907_77441098 3.76 Gm35920
predicted gene, 35920
16915
0.15
chr4_135337260_135337516 3.63 Srrm1
serine/arginine repetitive matrix 1
685
0.56
chr18_12257686_12257847 3.62 Ankrd29
ankyrin repeat domain 29
13931
0.14
chr8_22875512_22875922 3.52 Gm45555
predicted gene 45555
2128
0.26
chr16_24782017_24782185 3.49 Mir28a
microRNA 28a
45754
0.16
chr4_6239539_6239806 3.46 Gm11798
predicted gene 11798
21293
0.18
chr16_8189232_8189397 3.45 Gm49535
predicted gene, 49535
85526
0.09
chr3_113539787_113539957 3.38 Amy2a1
amylase 2a1
7444
0.22
chr1_106013874_106014051 3.34 Zcchc2
zinc finger, CCHC domain containing 2
2218
0.27
chr4_133008367_133008527 3.31 Ahdc1
AT hook, DNA binding motif, containing 1
2813
0.24
chr4_63355519_63355670 3.29 Orm3
orosomucoid 3
568
0.61
chr10_89467947_89468098 3.29 Gas2l3
growth arrest-specific 2 like 3
24055
0.19
chr16_46879425_46879587 3.26 Gm6912
predicted gene 6912
194692
0.03
chr17_64760017_64760177 3.26 Gm17133
predicted gene 17133
6001
0.2
chr17_43257833_43258015 3.26 Adgrf1
adhesion G protein-coupled receptor F1
12405
0.26
chr13_52736343_52736501 3.11 BB123696
expressed sequence BB123696
814
0.75
chr12_52448577_52448767 3.04 Gm47431
predicted gene, 47431
547
0.79
chr9_24515275_24515451 3.03 Gm47772
predicted gene, 47772
11914
0.21
chr1_75285156_75285327 3.01 Resp18
regulated endocrine-specific protein 18
6826
0.09
chr14_17725379_17725593 2.96 Gm48320
predicted gene, 48320
45636
0.18
chr5_147549154_147549347 2.91 Pan3
PAN3 poly(A) specific ribonuclease subunit
9973
0.2
chr2_181529212_181529615 2.89 Dnajc5
DnaJ heat shock protein family (Hsp40) member C5
8466
0.1
chr7_30969422_30969656 2.87 Lsr
lipolysis stimulated lipoprotein receptor
3783
0.09
chr18_12697874_12698426 2.80 Ttc39c
tetratricopeptide repeat domain 39C
8422
0.15
chr15_102102548_102102719 2.79 Tns2
tensin 2
301
0.83
chr8_122985769_122985939 2.79 Gm24445
predicted gene, 24445
2911
0.19
chr18_74642196_74642355 2.79 Myo5b
myosin VB
9098
0.25
chr12_103947018_103947616 2.75 Serpina1e
serine (or cysteine) peptidase inhibitor, clade A, member 1E
9581
0.11
chr4_63349571_63349895 2.72 Gm11212
predicted gene 11212
678
0.54
chr4_63343966_63344293 2.68 Orm1
orosomucoid 1
431
0.73
chr1_31051365_31051516 2.63 Gm28644
predicted gene 28644
9521
0.17
chr13_31511172_31511336 2.60 Foxq1
forkhead box Q1
44880
0.1
chr14_17699964_17700170 2.60 Thrb
thyroid hormone receptor beta
39171
0.2
chr16_15889632_15889951 2.56 Cebpd
CCAAT/enhancer binding protein (C/EBP), delta
1375
0.43
chr10_44700574_44700725 2.56 Gm47388
predicted gene, 47388
3469
0.15
chr4_6937290_6937452 2.53 Tox
thymocyte selection-associated high mobility group box
53112
0.17
chr2_85047151_85047302 2.52 Tnks1bp1
tankyrase 1 binding protein 1
796
0.47
chr8_95450058_95450271 2.51 Csnk2a2
casein kinase 2, alpha prime polypeptide
10550
0.12
chr19_4493105_4493260 2.51 2010003K11Rik
RIKEN cDNA 2010003K11 gene
5401
0.13
chr11_101448554_101448870 2.51 Ifi35
interferon-induced protein 35
142
0.87
chr3_116271828_116272000 2.49 Gpr88
G-protein coupled receptor 88
18411
0.18
chr15_100466736_100467062 2.47 5330439K02Rik
RIKEN cDNA 5330439K02 gene
1792
0.19
chr3_99984293_99984453 2.47 Rpl36-ps7
ribosomal protein L36, pseudogene 7
23987
0.19
chr7_102310929_102311109 2.46 Stim1
stromal interaction molecule 1
42692
0.09
chr8_105104341_105104511 2.44 Gm8804
predicted gene 8804
6198
0.11
chr1_54912808_54913219 2.43 A130048G24Rik
RIKEN cDNA A130048G24 gene
3581
0.23
chr11_118249114_118249306 2.42 Cyth1
cytohesin 1
618
0.69
chr13_30359952_30360149 2.38 Gm48161
predicted gene, 48161
10309
0.19
chr15_81834409_81834560 2.36 Gm8444
predicted gene 8444
9229
0.09
chr1_140407811_140407986 2.33 Kcnt2
potassium channel, subfamily T, member 2
35038
0.22
chr2_103209491_103209661 2.31 Gm13869
predicted gene 13869
781
0.62
chr13_103589765_103589942 2.26 Gm24870
predicted gene, 24870
52073
0.16
chr9_48723700_48723921 2.25 Zbtb16
zinc finger and BTB domain containing 16
112135
0.06
chr1_164460986_164461180 2.24 Gm32391
predicted gene, 32391
1359
0.33
chr2_30175455_30175643 2.23 Spout1
SPOUT domain containing methyltransferase 1
1956
0.17
chr9_44086416_44086600 2.20 Usp2
ubiquitin specific peptidase 2
682
0.41
chr15_77243081_77243232 2.19 Gm24056
predicted gene, 24056
605
0.67
chr10_59974206_59974563 2.17 Anapc16
anaphase promoting complex subunit 16
15999
0.16
chr2_116984707_116984867 2.11 Gm29340
predicted gene 29340
8359
0.2
chrX_140513451_140513611 2.11 Tsc22d3
TSC22 domain family, member 3
29137
0.16
chr7_30220091_30220286 2.09 Tbcb
tubulin folding cofactor B
6812
0.07
chr2_85071072_85071223 2.08 Tnks1bp1
tankyrase 1 binding protein 1
10183
0.12
chr1_67139611_67139949 2.08 Cps1
carbamoyl-phosphate synthetase 1
16754
0.23
chr8_40919479_40919678 2.07 Pdgfrl
platelet-derived growth factor receptor-like
6634
0.18
chr2_165873335_165873516 2.04 Zmynd8
zinc finger, MYND-type containing 8
2352
0.22
chr5_135368416_135368704 2.03 Nsun5
NOL1/NOP2/Sun domain family, member 5
1393
0.29
chr11_35693250_35693421 2.02 Pank3
pantothenate kinase 3
76149
0.08
chr8_24429693_24429861 2.00 Gm26714
predicted gene, 26714
7373
0.15
chr4_28646265_28646424 1.99 Gm11913
predicted gene 11913
34018
0.16
chr10_60082039_60082224 1.97 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
24088
0.17
chr7_121906959_121907182 1.92 Scnn1b
sodium channel, nonvoltage-gated 1 beta
7842
0.18
chr11_113140051_113140245 1.90 2610035D17Rik
RIKEN cDNA 2610035D17 gene
32929
0.22
chr17_28523067_28523337 1.87 Gm20109
predicted gene, 20109
54
0.53
chr12_79103944_79104118 1.86 9230116L04Rik
RIKEN cDNA 9230116L04 gene
92
0.94
chr10_69104650_69104828 1.82 Gm47107
predicted gene, 47107
6873
0.19
chr10_110716862_110717029 1.80 E2f7
E2F transcription factor 7
28494
0.19
chr19_36749089_36749269 1.78 Ppp1r3c
protein phosphatase 1, regulatory subunit 3C
12526
0.21
chr17_47508103_47508259 1.76 Ccnd3
cyclin D3
2940
0.19
chrX_97748755_97748912 1.71 Gm9062
predicted gene 9062
77546
0.12
chr12_84316137_84316351 1.71 Zfp410
zinc finger protein 410
608
0.47
chr15_75828201_75828376 1.69 Zc3h3
zinc finger CCCH type containing 3
79
0.95
chr18_12734331_12734736 1.69 Ttc39c
tetratricopeptide repeat domain 39C
172
0.93
chr8_123236815_123236966 1.69 Spata2l
spermatogenesis associated 2-like
657
0.4
chr12_40016922_40017297 1.69 Arl4a
ADP-ribosylation factor-like 4A
2625
0.28
chr11_86573938_86574127 1.68 Mir21a
microRNA 21a
10126
0.14
chr4_9846537_9846689 1.67 Gdf6
growth differentiation factor 6
2241
0.36
chr15_3359805_3359999 1.63 Ccdc152
coiled-coil domain containing 152
56376
0.14
chr6_146501770_146501939 1.62 Itpr2
inositol 1,4,5-triphosphate receptor 2
24
0.98
chr6_93150084_93150947 1.62 Gm5313
predicted gene 5313
12525
0.22
chr4_76289707_76290307 1.61 Ptprd
protein tyrosine phosphatase, receptor type, D
35236
0.22
chr7_119560394_119560545 1.60 Acsm2
acyl-CoA synthetase medium-chain family member 2
1024
0.4
chr19_3681085_3681312 1.59 Lrp5
low density lipoprotein receptor-related protein 5
5358
0.13
chr3_81938987_81939181 1.58 Ctso
cathepsin O
6441
0.17
chr13_52180080_52180254 1.57 Gm48199
predicted gene, 48199
244
0.95
chr5_92585719_92585883 1.57 Fam47e
family with sequence similarity 47, member E
14245
0.15
chr19_20650055_20650248 1.57 Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
48190
0.14
chr3_51373567_51373744 1.56 Gm37203
predicted gene, 37203
3433
0.12
chr6_34863513_34863693 1.56 Tmem140
transmembrane protein 140
341
0.81
chr3_138430446_138430657 1.54 Adh5
alcohol dehydrogenase 5 (class III), chi polypeptide
12542
0.12
chr3_97810411_97810572 1.54 Pde4dip
phosphodiesterase 4D interacting protein (myomegalin)
14130
0.2
chr15_31363364_31363533 1.52 Ankrd33b
ankyrin repeat domain 33B
4084
0.18
chr3_118606217_118606485 1.52 Dpyd
dihydropyrimidine dehydrogenase
44165
0.15
chr5_20590310_20590514 1.51 Gm3544
predicted gene 3544
1816
0.41
chr2_163595872_163596256 1.50 Ttpal
tocopherol (alpha) transfer protein-like
6250
0.15
chr1_154117784_154118141 1.50 A830008E24Rik
RIKEN cDNA A830008E24 gene
11
0.98
chr1_130764110_130764467 1.50 Gm28856
predicted gene 28856
2096
0.18
chr15_88875664_88876414 1.49 Pim3
proviral integration site 3
11119
0.13
chr9_55289930_55290101 1.49 Nrg4
neuregulin 4
6390
0.18
chr6_90509178_90509363 1.46 Gm44236
predicted gene, 44236
4032
0.14
chr4_45411492_45411708 1.46 Slc25a51
solute carrier family 25, member 51
2834
0.21
chr18_11144853_11145048 1.46 Gata6
GATA binding protein 6
85903
0.09
chr14_32179471_32179639 1.44 Ncoa4
nuclear receptor coactivator 4
2823
0.15
chr3_116951565_116951725 1.44 Gm42892
predicted gene 42892
7315
0.14
chr12_12910670_12910849 1.42 Rpl36-ps3
ribosomal protein L36, pseudogene 3
1263
0.28
chr4_125419601_125419754 1.42 Grik3
glutamate receptor, ionotropic, kainate 3
71023
0.1
chr18_56446982_56447133 1.40 Gramd3
GRAM domain containing 3
14925
0.19
chr4_57275390_57275611 1.40 Gm12536
predicted gene 12536
24596
0.17
chr16_91785546_91785722 1.40 Itsn1
intersectin 1 (SH3 domain protein 1A)
1529
0.38
chr16_4829305_4829483 1.40 4930562C15Rik
RIKEN cDNA 4930562C15 gene
6022
0.14
chr19_42566701_42566858 1.39 R3hcc1l
R3H domain and coiled-coil containing 1 like
2538
0.25
chr16_37871477_37871675 1.36 Lrrc58
leucine rich repeat containing 58
3187
0.18
chr4_123025711_123025964 1.36 Trit1
tRNA isopentenyltransferase 1
9240
0.15
chr13_94441400_94441551 1.35 Ap3b1
adaptor-related protein complex 3, beta 1 subunit
31388
0.17
chr12_44270303_44270622 1.35 Pnpla8
patatin-like phospholipase domain containing 8
1295
0.31
chr7_122074308_122074464 1.35 Ubfd1
ubiquitin family domain containing 1
5487
0.11
chr1_67184194_67184631 1.34 Cps1
carbamoyl-phosphate synthetase 1
61386
0.11
chr10_43518549_43518719 1.34 Gm47889
predicted gene, 47889
63
0.96
chr13_24144161_24144442 1.33 Carmil1
capping protein regulator and myosin 1 linker 1
10908
0.19
chr7_119961192_119961374 1.33 Dnah3
dynein, axonemal, heavy chain 3
6559
0.16
chr14_89799296_89799771 1.33 Gm25415
predicted gene, 25415
92728
0.09
chr13_101719396_101719571 1.33 Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
17379
0.2
chr6_90464556_90464771 1.32 Klf15
Kruppel-like factor 15
641
0.55
chr4_108348266_108348457 1.31 Coa7
cytochrome c oxidase assembly factor 7
20172
0.11
chr11_28695120_28695290 1.30 2810471M01Rik
RIKEN cDNA 2810471M01 gene
13641
0.17
chr16_37870060_37870244 1.27 Lrrc58
leucine rich repeat containing 58
1763
0.26
chr8_34164335_34164526 1.26 Mir6395
microRNA 6395
2282
0.18
chr7_81110178_81110363 1.25 Slc28a1
solute carrier family 28 (sodium-coupled nucleoside transporter), member 1
4529
0.17
chr16_30964451_30964794 1.21 Gm15742
predicted gene 15742
8896
0.18
chr7_114817644_114817801 1.21 Gm24982
predicted gene, 24982
14792
0.17
chr11_80974682_80974867 1.19 Gm11416
predicted gene 11416
72020
0.1
chr4_59196341_59196952 1.19 Ugcg
UDP-glucose ceramide glucosyltransferase
7088
0.18
chr9_103211099_103211533 1.17 Trf
transferrin
690
0.65
chr19_10167207_10167390 1.16 Gm50359
predicted gene, 50359
8863
0.11
chr18_12667973_12668145 1.16 Gm41668
predicted gene, 41668
19640
0.13

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Nr3c2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.6 3.9 GO:0070995 NADPH oxidation(GO:0070995)
0.3 3.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.3 0.8 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.3 5.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.3 1.6 GO:0042737 drug catabolic process(GO:0042737)
0.3 0.5 GO:0034756 regulation of iron ion transport(GO:0034756)
0.3 1.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 0.5 GO:0009812 flavonoid metabolic process(GO:0009812)
0.2 1.2 GO:0060023 soft palate development(GO:0060023)
0.2 2.1 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.2 0.7 GO:0032439 endosome localization(GO:0032439)
0.2 1.6 GO:0010793 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.2 0.9 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.2 0.9 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 0.6 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.2 0.4 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.2 0.4 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.2 0.6 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.2 0.8 GO:0097460 ferrous iron import into cell(GO:0097460)
0.2 0.9 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.2 0.6 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.2 0.4 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.2 2.2 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.2 0.5 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.2 0.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.2 1.6 GO:0071361 cellular response to ethanol(GO:0071361)
0.2 0.8 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 0.3 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.2 0.7 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 0.5 GO:0006808 regulation of nitrogen utilization(GO:0006808)
0.2 0.6 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.1 2.5 GO:0014850 response to muscle activity(GO:0014850)
0.1 2.2 GO:0045056 transcytosis(GO:0045056)
0.1 1.9 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 1.3 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.1 0.5 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.5 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.4 GO:0032741 positive regulation of interleukin-18 production(GO:0032741)
0.1 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.7 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 0.1 GO:0070627 ferrous iron import(GO:0070627)
0.1 0.9 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.4 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.1 0.5 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 0.7 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.1 0.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.3 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 0.4 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 0.3 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.1 1.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.3 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
0.1 0.4 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.1 0.3 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.4 GO:0006067 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.1 0.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 0.4 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1 0.3 GO:0015819 lysine transport(GO:0015819)
0.1 0.3 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.1 0.3 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1 0.6 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.7 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 1.2 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.6 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.2 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.5 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 0.2 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.2 GO:0016553 base conversion or substitution editing(GO:0016553)
0.1 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.1 GO:0060331 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.1 1.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 0.7 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.5 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.3 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 2.6 GO:0006953 acute-phase response(GO:0006953)
0.1 0.4 GO:0006265 DNA topological change(GO:0006265)
0.1 0.2 GO:0060486 Clara cell differentiation(GO:0060486)
0.1 0.3 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.1 0.2 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.3 GO:0048539 bone marrow development(GO:0048539)
0.1 0.1 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.2 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.1 GO:0002215 defense response to nematode(GO:0002215)
0.1 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.3 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.3 GO:0032532 regulation of microvillus length(GO:0032532)
0.0 0.0 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.4 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.1 GO:0060178 regulation of exocyst localization(GO:0060178)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.0 GO:0072053 renal inner medulla development(GO:0072053)
0.0 0.5 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.4 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.2 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.2 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.5 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 4.9 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.6 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.0 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.2 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.6 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.2 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.2 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.2 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.1 GO:1904238 pericyte cell differentiation(GO:1904238)
0.0 0.0 GO:2000384 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.0 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.0 GO:0052330 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.1 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.0 0.2 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.0 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.1 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.2 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 1.5 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.1 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.0 0.4 GO:0017144 drug metabolic process(GO:0017144)
0.0 0.1 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.2 GO:0042473 outer ear morphogenesis(GO:0042473)
0.0 0.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 1.7 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.1 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.2 GO:0060717 chorion development(GO:0060717) extraembryonic membrane development(GO:1903867)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.1 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.1 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.2 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0 0.0 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.1 GO:0002424 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0 0.3 GO:0002176 male germ cell proliferation(GO:0002176)
0.0 0.1 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0045794 negative regulation of cell volume(GO:0045794)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.1 GO:0006549 isoleucine metabolic process(GO:0006549) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.0 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.5 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.3 GO:0032986 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.1 GO:0031052 programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052)
0.0 0.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.0 0.0 GO:2001182 regulation of interleukin-12 secretion(GO:2001182)
0.0 0.1 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.2 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.1 GO:1990845 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.4 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313)
0.0 0.0 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.3 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.0 GO:0034370 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.2 GO:0071404 cellular response to low-density lipoprotein particle stimulus(GO:0071404)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.0 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:1990168 protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.1 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 1.1 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0036394 amylase secretion(GO:0036394)
0.0 0.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.3 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.2 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 0.1 GO:0001781 neutrophil apoptotic process(GO:0001781)
0.0 0.0 GO:0086068 Purkinje myocyte action potential(GO:0086017) Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.0 0.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.0 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.4 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.0 GO:2000561 regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.2 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.0 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.3 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:1903797 regulation of inorganic anion transmembrane transport(GO:1903795) positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0 0.0 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.2 GO:0051923 sulfation(GO:0051923)
0.0 0.2 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.1 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.0 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.6 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.0 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.3 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.0 GO:1901662 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0 0.0 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.0 GO:1903998 regulation of eating behavior(GO:1903998)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.0 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.0 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.0 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.0 GO:0010988 regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0 0.0 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.6 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.0 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.9 GO:1901216 positive regulation of neuron death(GO:1901216)
0.0 0.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.0 GO:1903525 regulation of membrane tubulation(GO:1903525)
0.0 0.0 GO:0060956 endocardial cell differentiation(GO:0060956)
0.0 0.1 GO:0034398 telomere tethering at nuclear periphery(GO:0034398)
0.0 0.0 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 0.4 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:0032789 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0 0.0 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.0 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0016045 detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0 0.0 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.0 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.2 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.1 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.0 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.0 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.0 GO:0051593 response to folic acid(GO:0051593)
0.0 0.0 GO:0070141 response to UV-A(GO:0070141)
0.0 0.0 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.0 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.5 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.0 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.0 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.4 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.0 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.0 0.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0071435 potassium ion export(GO:0071435)
0.0 0.2 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.1 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.0 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.4 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.1 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.0 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.5 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.9 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.0 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.0 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884)
0.0 0.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.0 GO:0002884 regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884)
0.0 1.8 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.1 GO:0090208 positive regulation of triglyceride metabolic process(GO:0090208)
0.0 0.0 GO:0035483 gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883) positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.0 GO:0003139 secondary heart field specification(GO:0003139) cardiac cell fate determination(GO:0060913)
0.0 0.1 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.1 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.0 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.0 GO:0014735 regulation of muscle atrophy(GO:0014735)
0.0 0.0 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.0 0.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.4 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.0 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0051255 spindle midzone assembly(GO:0051255)
0.0 0.0 GO:0046103 inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.0 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.2 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.0 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.0 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.0 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.0 GO:0061046 regulation of branching involved in lung morphogenesis(GO:0061046)
0.0 0.0 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141) positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.0 GO:0051799 negative regulation of hair follicle development(GO:0051799)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.3 1.3 GO:0005955 calcineurin complex(GO:0005955)
0.2 0.9 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 0.6 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.2 0.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.8 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 5.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.3 GO:0043293 apoptosome(GO:0043293)
0.1 0.6 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.5 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.4 GO:1990716 axonemal central apparatus(GO:1990716)
0.1 0.7 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.0 GO:0071565 nBAF complex(GO:0071565)
0.1 1.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.6 GO:0045179 apical cortex(GO:0045179)
0.1 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.2 GO:0005608 laminin-3 complex(GO:0005608)
0.1 0.5 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.4 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.4 GO:0032009 early phagosome(GO:0032009)
0.1 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 2.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 1.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0002142 stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.0 GO:0044453 nuclear membrane part(GO:0044453)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 1.8 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0005712 chiasma(GO:0005712)
0.0 1.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.4 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 1.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 2.4 GO:0070160 occluding junction(GO:0070160)
0.0 0.1 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.3 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0043194 axon initial segment(GO:0043194)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.0 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.0 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.0 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.9 GO:0043195 terminal bouton(GO:0043195)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 15.9 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 1.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.0 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0043296 apical junction complex(GO:0043296)
0.0 0.0 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0034705 potassium channel complex(GO:0034705)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 0.0 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.0 GO:0009279 cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0 0.2 GO:0008305 integrin complex(GO:0008305)
0.0 0.4 GO:0043679 axon terminus(GO:0043679)
0.0 0.0 GO:0005640 nuclear outer membrane(GO:0005640)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.6 1.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.4 1.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.3 5.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.3 1.7 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.3 3.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 0.7 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.2 0.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 0.6 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.2 0.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 0.9 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 0.5 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.2 0.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 0.2 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
0.1 0.7 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.7 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.4 GO:0031711 bradykinin receptor binding(GO:0031711)
0.1 0.7 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.1 0.4 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.2 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 2.2 GO:0052831 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.1 0.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.8 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.2 GO:2001070 starch binding(GO:2001070)
0.1 0.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.1 5.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.1 GO:0015927 trehalase activity(GO:0015927)
0.1 0.2 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.1 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.4 GO:0043426 MRF binding(GO:0043426)
0.1 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.6 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0009374 biotin binding(GO:0009374)
0.1 0.5 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.2 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.1 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.1 4.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 2.6 GO:0005548 phospholipid transporter activity(GO:0005548)
0.1 1.6 GO:0043883 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.1 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.3 GO:0050733 RS domain binding(GO:0050733)
0.1 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.4 GO:0046030 inositol trisphosphate phosphatase activity(GO:0046030)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.3 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0045340 mercury ion binding(GO:0045340)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0046870 cobalt ion transmembrane transporter activity(GO:0015087) cadmium ion binding(GO:0046870)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.3 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.9 GO:0030515 snoRNA binding(GO:0030515)
0.0 1.1 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 1.1 GO:0043908 prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0 0.2 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.2 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 1.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0 0.6 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.0 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.5 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 2.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.3 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.8 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.0 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0044105 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.3 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0016215 acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0030249 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.0 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.0 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.0 GO:0032190 acrosin binding(GO:0032190)
0.0 1.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.0 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.0 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 0.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.7 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0015266 protein channel activity(GO:0015266)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.0 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.0 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.5 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.0 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.0 0.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.0 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0032183 SUMO binding(GO:0032183)
0.0 0.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0032182 ubiquitin-like protein binding(GO:0032182)
0.0 0.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.3 GO:0045543 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 0.0 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.4 GO:0043022 ribosome binding(GO:0043022)
0.0 0.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.0 GO:0004046 aminoacylase activity(GO:0004046)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 ST ADRENERGIC Adrenergic Pathway
0.1 1.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 4.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 0.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.9 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.1 PID FOXO PATHWAY FoxO family signaling
0.0 0.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.4 3.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 2.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 1.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 1.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 5.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 0.9 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.5 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.1 1.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.7 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 2.2 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.4 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.0 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)